Mus musculus

0 known processes

Pgcp

plasma glutamate carboxypeptidase

(Aliases: Lal-1,Hls2,1190003P12Rik,2610034C17Rik)

Pgcp biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular ketone metabolic process GO:0010565 66 0.091
amine metabolic process GO:0009308 45 0.089
cellular ketone metabolic process GO:0042180 84 0.079
oxidation reduction process GO:0055114 342 0.076
cellular amine metabolic process GO:0044106 44 0.066
cellular amino acid metabolic process GO:0006520 103 0.064
Rat
regulation of defense response GO:0031347 233 0.053
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.050
regulation of cellular amine metabolic process GO:0033238 20 0.048
protein maturation GO:0051604 176 0.046
organonitrogen compound biosynthetic process GO:1901566 192 0.045
regulation of cellular amino acid metabolic process GO:0006521 5 0.044
response to molecule of bacterial origin GO:0002237 143 0.042
skeletal system development GO:0001501 356 0.040
negative regulation of phosphorus metabolic process GO:0010563 184 0.040
inflammatory response GO:0006954 244 0.039
cytokine production GO:0001816 319 0.039
regulation of peptidase activity GO:0052547 96 0.039
positive regulation of cellular amine metabolic process GO:0033240 5 0.035
protein processing GO:0016485 163 0.034
nucleoside phosphate metabolic process GO:0006753 338 0.034
immune effector process GO:0002252 321 0.032
cation transport GO:0006812 399 0.032
regulation of cytokine production GO:0001817 266 0.032
extracellular structure organization GO:0043062 148 0.032
organic hydroxy compound metabolic process GO:1901615 203 0.031
Rat
response to organic cyclic compound GO:0014070 198 0.031
carbohydrate derivative biosynthetic process GO:1901137 183 0.031
cellular lipid metabolic process GO:0044255 323 0.031
cytoplasmic transport GO:0016482 234 0.030
ribose phosphate metabolic process GO:0019693 291 0.030
regulation of secretion GO:0051046 274 0.030
ear development GO:0043583 200 0.030
aromatic compound catabolic process GO:0019439 286 0.030
regulation of inflammatory response GO:0050727 147 0.029
leukocyte mediated immunity GO:0002443 174 0.029
positive regulation of defense response GO:0031349 124 0.029
reactive oxygen species metabolic process GO:0072593 84 0.029
reactive oxygen species biosynthetic process GO:1903409 8 0.028
lipid biosynthetic process GO:0008610 179 0.028
reactive nitrogen species metabolic process GO:2001057 0 0.028
nucleobase containing small molecule metabolic process GO:0055086 352 0.028
peptidyl amino acid modification GO:0018193 336 0.028
negative regulation of cellular protein metabolic process GO:0032269 247 0.028
negative regulation of protein metabolic process GO:0051248 282 0.028
cation transmembrane transport GO:0098655 266 0.028
response to organonitrogen compound GO:0010243 246 0.028
cellular chemical homeostasis GO:0055082 215 0.027
positive regulation of protein modification process GO:0031401 299 0.027
negative regulation of cell proliferation GO:0008285 296 0.027
cellular homeostasis GO:0019725 240 0.026
positive regulation of protein kinase activity GO:0045860 144 0.026
negative regulation of molecular function GO:0044092 258 0.026
mapk cascade GO:0000165 281 0.025
positive regulation of t cell mediated cytotoxicity GO:0001916 15 0.025
heterocycle catabolic process GO:0046700 280 0.025
multicellular organismal homeostasis GO:0048871 164 0.025
leukocyte differentiation GO:0002521 342 0.025
purine nucleotide metabolic process GO:0006163 302 0.024
response to growth factor GO:0070848 198 0.024
regulation of protein maturation GO:1903317 96 0.024
nitrogen compound transport GO:0071705 271 0.024
monocarboxylic acid metabolic process GO:0032787 191 0.023
negative regulation of phosphate metabolic process GO:0045936 184 0.023
t cell activation GO:0042110 289 0.023
positive regulation of cytokine production GO:0001819 174 0.023
sequestering of calcium ion GO:0051208 18 0.023
carbohydrate derivative catabolic process GO:1901136 231 0.023
male gamete generation GO:0048232 285 0.023
regulation of reactive oxygen species metabolic process GO:2000377 40 0.023
positive regulation of protein phosphorylation GO:0001934 242 0.023
response to extracellular stimulus GO:0009991 127 0.023
nucleotide metabolic process GO:0009117 332 0.022
regulation of membrane potential GO:0042391 192 0.022
regulation of proteolysis GO:0030162 164 0.022
cell type specific apoptotic process GO:0097285 268 0.022
negative regulation of immune system process GO:0002683 209 0.022
glucose homeostasis GO:0042593 128 0.022
small molecule biosynthetic process GO:0044283 132 0.022
nucleoside triphosphate metabolic process GO:0009141 230 0.022
carbohydrate metabolic process GO:0005975 230 0.021
regulation of secretion by cell GO:1903530 249 0.021
cellular ion homeostasis GO:0006873 165 0.021
apoptotic signaling pathway GO:0097190 306 0.021
sulfur compound metabolic process GO:0006790 100 0.021
organic cyclic compound catabolic process GO:1901361 295 0.021
ribonucleotide metabolic process GO:0009259 291 0.021
regulation of apoptotic signaling pathway GO:2001233 197 0.021
ras protein signal transduction GO:0007265 77 0.021
cellular nitrogen compound catabolic process GO:0044270 280 0.021
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.020
extracellular matrix organization GO:0030198 147 0.020
blood circulation GO:0008015 195 0.020
regulation of transferase activity GO:0051338 263 0.020
leukocyte mediated cytotoxicity GO:0001909 62 0.020
innate immune response GO:0045087 157 0.020
regulation of hydrolase activity GO:0051336 246 0.020
extrinsic apoptotic signaling pathway GO:0097191 126 0.020
organonitrogen compound catabolic process GO:1901565 264 0.020
Human
regulation of protein transport GO:0051223 163 0.020
lymphocyte mediated immunity GO:0002449 139 0.019
fatty acid metabolic process GO:0006631 121 0.019
intracellular protein transport GO:0006886 204 0.019
anion transport GO:0006820 177 0.019
regulation of cell motility GO:2000145 236 0.019
cellular response to organonitrogen compound GO:0071417 145 0.019
regulation of endopeptidase activity GO:0052548 89 0.019
cellular response to lipid GO:0071396 145 0.019
positive regulation of apoptotic process GO:0043065 217 0.019
protein catabolic process GO:0030163 221 0.019
response to nutrient levels GO:0031667 109 0.019
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.018
spermatogenesis GO:0007283 284 0.018
response to acid chemical GO:0001101 111 0.018
regulation of response to wounding GO:1903034 189 0.018
isoprenoid metabolic process GO:0006720 29 0.018
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.018
cellular response to growth factor stimulus GO:0071363 197 0.018
regulation of cellular response to growth factor stimulus GO:0090287 82 0.018
macromolecule catabolic process GO:0009057 281 0.018
compound eye development GO:0048749 1 0.018
regulation of establishment of protein localization GO:0070201 181 0.018
cell adhesion GO:0007155 329 0.018
positive regulation of hydrolase activity GO:0051345 148 0.018
cation homeostasis GO:0055080 212 0.018
organophosphate catabolic process GO:0046434 232 0.018
regulation of protein kinase activity GO:0045859 232 0.018
organophosphate biosynthetic process GO:0090407 122 0.018
skeletal system morphogenesis GO:0048705 203 0.018
positive regulation of kinase activity GO:0033674 155 0.018
cell activation involved in immune response GO:0002263 126 0.018
ossification GO:0001503 216 0.018
regulation of lymphocyte activation GO:0051249 240 0.017
response to lipopolysaccharide GO:0032496 128 0.017
regulation of fatty acid oxidation GO:0046320 10 0.017
cellular response to molecule of bacterial origin GO:0071219 83 0.017
nucleoside metabolic process GO:0009116 246 0.017
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.017
regulation of cellular catabolic process GO:0031329 242 0.017
transmembrane transport GO:0055085 412 0.017
response to oxidative stress GO:0006979 123 0.017
sequestering of metal ion GO:0051238 19 0.017
cartilage development GO:0051216 140 0.017
interferon gamma production GO:0032609 67 0.017
protein secretion GO:0009306 111 0.017
synaptic transmission GO:0007268 329 0.017
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.017
myeloid cell differentiation GO:0030099 233 0.017
cellular response to lipopolysaccharide GO:0071222 77 0.017
metal ion homeostasis GO:0055065 189 0.017
positive regulation of secretion by cell GO:1903532 114 0.017
regulation of intracellular transport GO:0032386 159 0.016
respiratory system development GO:0060541 190 0.016
small gtpase mediated signal transduction GO:0007264 97 0.016
regulation of body fluid levels GO:0050878 162 0.016
positive regulation of mapk cascade GO:0043410 170 0.016
lymphocyte differentiation GO:0030098 242 0.016
activation of immune response GO:0002253 138 0.016
purine containing compound metabolic process GO:0072521 311 0.016
membrane organization GO:0061024 245 0.016
lymphocyte activation involved in immune response GO:0002285 93 0.016
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.016
negative regulation of protein phosphorylation GO:0001933 126 0.016
positive regulation of transferase activity GO:0051347 167 0.016
purine ribonucleoside catabolic process GO:0046130 205 0.016
regulation of cell projection organization GO:0031344 206 0.016
small molecule catabolic process GO:0044282 71 0.016
positive regulation of cell development GO:0010720 237 0.016
rho protein signal transduction GO:0007266 32 0.016
production of molecular mediator of immune response GO:0002440 103 0.016
positive regulation of programmed cell death GO:0043068 218 0.016
negative regulation of phosphorylation GO:0042326 166 0.016
wound healing GO:0042060 157 0.015
Rat
regulation of protein processing GO:0070613 96 0.015
regulation of cell adhesion GO:0030155 154 0.015
purine ribonucleoside metabolic process GO:0046128 241 0.015
establishment of blood nerve barrier GO:0008065 3 0.015
positive regulation of apoptotic signaling pathway GO:2001235 95 0.015
regulation of voltage gated calcium channel activity GO:1901385 4 0.015
negative regulation of proteolysis GO:0045861 74 0.015
regulation of mapk cascade GO:0043408 248 0.015
regulation of adaptive immune response GO:0002819 90 0.015
cellular response to biotic stimulus GO:0071216 92 0.015
regulation of neuron projection development GO:0010975 169 0.015
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.015
purine nucleotide catabolic process GO:0006195 211 0.015
response to inorganic substance GO:0010035 96 0.015
negative regulation of protein processing GO:0010955 79 0.014
regulation of kinase activity GO:0043549 249 0.014
ion transmembrane transport GO:0034220 361 0.014
cell substrate adhesion GO:0031589 130 0.014
respiratory tube development GO:0030323 167 0.014
myeloid leukocyte differentiation GO:0002573 119 0.014
lung development GO:0030324 164 0.014
organic anion transport GO:0015711 137 0.014
appendage development GO:0048736 166 0.014
regulation of cytokine secretion GO:0050707 61 0.014
purine ribonucleotide metabolic process GO:0009150 290 0.014
regulation of protein serine threonine kinase activity GO:0071900 157 0.014
ribonucleoside triphosphate metabolic process GO:0009199 220 0.014
regulation of organelle organization GO:0033043 289 0.014
peptide transport GO:0015833 133 0.014
dna metabolic process GO:0006259 303 0.014
nucleocytoplasmic transport GO:0006913 139 0.014
regulation of protein localization GO:0032880 231 0.014
regulation of cell activation GO:0050865 289 0.014
alcohol metabolic process GO:0006066 116 0.014
negative regulation of intracellular signal transduction GO:1902532 167 0.014
regulation of innate immune response GO:0045088 91 0.014
positive regulation of protein transport GO:0051222 93 0.014
divalent inorganic cation transport GO:0072511 178 0.014
wnt signaling pathway GO:0016055 188 0.014
neuron death GO:0070997 154 0.014
regulation of interferon gamma production GO:0032649 57 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.014
regulation of ras protein signal transduction GO:0046578 114 0.014
cellular response to hormone stimulus GO:0032870 150 0.014
negative regulation of hydrolase activity GO:0051346 71 0.014
lymphocyte proliferation GO:0046651 164 0.014
positive regulation of cell death GO:0010942 224 0.014
protein localization to organelle GO:0033365 185 0.013
regulation of cell cycle GO:0051726 281 0.013
endocytosis GO:0006897 168 0.013
regulation of lymphocyte mediated immunity GO:0002706 84 0.013
leukocyte migration GO:0050900 124 0.013
lipid transport GO:0006869 98 0.013
regulation of vesicle mediated transport GO:0060627 139 0.013
cellular macromolecule catabolic process GO:0044265 206 0.013
camera type eye development GO:0043010 266 0.013
cellular metal ion homeostasis GO:0006875 151 0.013
protein localization to membrane GO:0072657 108 0.013
positive regulation of immune effector process GO:0002699 107 0.013
glycosyl compound metabolic process GO:1901657 246 0.013
connective tissue development GO:0061448 179 0.013
cellular response to cytokine stimulus GO:0071345 189 0.013
regulation of lipid metabolic process GO:0019216 118 0.013
lipid catabolic process GO:0016042 69 0.013
peptide metabolic process GO:0006518 46 0.013
Human
glycoprotein biosynthetic process GO:0009101 89 0.013
divalent metal ion transport GO:0070838 172 0.013
terpenoid metabolic process GO:0006721 25 0.013
organ regeneration GO:0031100 2 0.013
positive regulation of nervous system development GO:0051962 221 0.013
endomembrane system organization GO:0010256 147 0.013
t cell proliferation GO:0042098 120 0.012
developmental growth involved in morphogenesis GO:0060560 138 0.012
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.012
blood coagulation GO:0007596 76 0.012
leukocyte activation involved in immune response GO:0002366 126 0.012
adaptive immune response GO:0002250 155 0.012
positive regulation of secretion GO:0051047 130 0.012
response to oxygen levels GO:0070482 62 0.012
alpha beta t cell activation GO:0046631 91 0.012
angiogenesis GO:0001525 201 0.012
multi multicellular organism process GO:0044706 109 0.012
regulation of hormone levels GO:0010817 211 0.012
Rat
purine nucleoside triphosphate metabolic process GO:0009144 226 0.012
organic acid catabolic process GO:0016054 51 0.012
carboxylic acid catabolic process GO:0046395 51 0.012
glycerolipid metabolic process GO:0046486 122 0.012
regulation of neuron differentiation GO:0045664 281 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.012
lipid localization GO:0010876 126 0.012
amide transport GO:0042886 138 0.012
defense response to other organism GO:0098542 197 0.012
embryonic organ morphogenesis GO:0048562 276 0.012
regulation of cytoplasmic transport GO:1903649 112 0.012
glycosyl compound catabolic process GO:1901658 206 0.012
t cell mediated immunity GO:0002456 50 0.012
negative regulation of cellular component organization GO:0051129 194 0.012
gland development GO:0048732 330 0.012
carbohydrate homeostasis GO:0033500 128 0.012
locomotory behavior GO:0007626 195 0.012
nucleoside phosphate catabolic process GO:1901292 222 0.012
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.012
renal system development GO:0072001 225 0.012
chemotaxis GO:0006935 247 0.012
cytokine production involved in immune response GO:0002367 34 0.012
multicellular organism growth GO:0035264 161 0.012
cellular response to dna damage stimulus GO:0006974 207 0.012
morphogenesis of a branching structure GO:0001763 203 0.012
ribonucleoside catabolic process GO:0042454 206 0.012
cellular protein complex assembly GO:0043623 116 0.012
carboxylic acid transport GO:0046942 100 0.011
carboxylic acid biosynthetic process GO:0046394 86 0.011
diterpenoid metabolic process GO:0016101 24 0.011
cytokine secretion GO:0050663 72 0.011
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.011
negative regulation of cellular amine metabolic process GO:0033239 1 0.011
organic hydroxy compound biosynthetic process GO:1901617 77 0.011
purine nucleoside metabolic process GO:0042278 241 0.011
sensory perception GO:0007600 245 0.011
cellular amide metabolic process GO:0043603 58 0.011
Human
nucleotide catabolic process GO:0009166 217 0.011
hemostasis GO:0007599 78 0.011
epithelial cell proliferation GO:0050673 174 0.011
canonical wnt signaling pathway GO:0060070 130 0.011
morphogenesis of a branching epithelium GO:0061138 193 0.011
cellular response to extracellular stimulus GO:0031668 81 0.011
regulation of leukocyte mediated immunity GO:0002703 104 0.011
acute inflammatory response GO:0002526 41 0.011
hormone metabolic process GO:0042445 86 0.011
Rat
coagulation GO:0050817 78 0.011
cellular response to nutrient levels GO:0031669 64 0.011
regulation of blood pressure GO:0008217 93 0.011
purine nucleoside triphosphate catabolic process GO:0009146 203 0.011
organelle localization GO:0051640 179 0.011
cellular response to starvation GO:0009267 57 0.011
inorganic cation transmembrane transport GO:0098662 207 0.011
purine ribonucleotide catabolic process GO:0009154 208 0.011
regulation of protein catabolic process GO:0042176 108 0.011
purine nucleoside catabolic process GO:0006152 205 0.011
organic hydroxy compound transport GO:0015850 93 0.011
bone mineralization GO:0030282 54 0.011
negative regulation of protein maturation GO:1903318 79 0.011
leukocyte proliferation GO:0070661 172 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.011
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.011
maintenance of location GO:0051235 89 0.011
methylation GO:0032259 134 0.011
regulation of protein secretion GO:0050708 82 0.011
defense response to bacterium GO:0042742 119 0.011
vesicle localization GO:0051648 86 0.011
interleukin 8 production GO:0032637 4 0.011
cellular response to oxidative stress GO:0034599 76 0.010
retinoid metabolic process GO:0001523 24 0.010
macromolecule glycosylation GO:0043413 55 0.010
ribonucleotide catabolic process GO:0009261 208 0.010
cellular response to organic cyclic compound GO:0071407 87 0.010
regulation of anatomical structure size GO:0090066 178 0.010
ribonucleoside metabolic process GO:0009119 245 0.010
smoothened signaling pathway GO:0007224 105 0.010
regulation of system process GO:0044057 200 0.010
regulation of ossification GO:0030278 112 0.010
positive regulation of map kinase activity GO:0043406 84 0.010
regulation of interleukin 8 production GO:0032677 3 0.010
positive regulation of endopeptidase activity GO:0010950 43 0.010
cellular lipid catabolic process GO:0044242 52 0.010
bone development GO:0060348 120 0.010
sensory organ morphogenesis GO:0090596 242 0.010
regulation of leukocyte apoptotic process GO:2000106 56 0.010
positive regulation of proteolysis GO:0045862 85 0.010
positive regulation of adaptive immune response GO:0002821 61 0.010
multicellular organismal signaling GO:0035637 91 0.010
regulation of ion transport GO:0043269 215 0.010

Pgcp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.051
inherited metabolic disorder DOID:655 0 0.051
disease of anatomical entity DOID:7 0 0.034
nervous system disease DOID:863 0 0.034
sensory system disease DOID:0050155 0 0.031
eye and adnexa disease DOID:1492 0 0.031
eye disease DOID:5614 0 0.031
immune system disease DOID:2914 0 0.030
hematopoietic system disease DOID:74 0 0.021
retinal disease DOID:5679 0 0.020
musculoskeletal system disease DOID:17 0 0.019
connective tissue disease DOID:65 0 0.019
retinal degeneration DOID:8466 0 0.018
central nervous system disease DOID:331 0 0.012
cardiovascular system disease DOID:1287 0 0.011
hemolytic anemia DOID:583 0 0.011
hemolytic uremic syndrome DOID:12554 0 0.011
normocytic anemia DOID:720 0 0.011
anemia DOID:2355 0 0.011
vascular disease DOID:178 0 0.011