Mus musculus

50 known processes

Ikzf3

IKAROS family zinc finger 3

(Aliases: Aiolos,Zfpn1a3,Znfn1a3,5830411O07Rik)

Ikzf3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
b cell proliferation GO:0042100 53 0.941
leukocyte proliferation GO:0070661 172 0.837
immune response activating signal transduction GO:0002757 116 0.817
lymphocyte proliferation GO:0046651 164 0.761
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.754
b cell activation GO:0042113 161 0.725
activation of immune response GO:0002253 138 0.684
antigen receptor mediated signaling pathway GO:0050851 64 0.649
lymphocyte differentiation GO:0030098 242 0.567
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.491
leukocyte differentiation GO:0002521 342 0.446
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.381
t cell differentiation GO:0030217 174 0.381
Mouse
b cell receptor signaling pathway GO:0050853 20 0.340
ribonucleoside catabolic process GO:0042454 206 0.333
t cell proliferation GO:0042098 120 0.320
organonitrogen compound catabolic process GO:1901565 264 0.300
nucleoside triphosphate catabolic process GO:0009143 205 0.297
regulation of b cell activation GO:0050864 81 0.287
release of sequestered calcium ion into cytosol GO:0051209 42 0.284
cellular amine metabolic process GO:0044106 44 0.282
regulation of lymphocyte proliferation GO:0050670 117 0.270
organic cyclic compound catabolic process GO:1901361 295 0.268
positive regulation of leukocyte proliferation GO:0070665 73 0.261
immune effector process GO:0002252 321 0.254
positive regulation of cellular amine metabolic process GO:0033240 5 0.254
positive regulation of gtpase activity GO:0043547 85 0.249
t cell selection GO:0045058 34 0.237
immune response regulating signaling pathway GO:0002764 125 0.235
purine nucleoside catabolic process GO:0006152 205 0.234
negative regulation of phosphorus metabolic process GO:0010563 184 0.232
ribonucleoside triphosphate catabolic process GO:0009203 199 0.227
regulation of leukocyte proliferation GO:0070663 121 0.226
cellular ketone metabolic process GO:0042180 84 0.225
organophosphate catabolic process GO:0046434 232 0.221
glycosyl compound catabolic process GO:1901658 206 0.220
positive regulation of b cell activation GO:0050871 49 0.217
Mouse
gtp catabolic process GO:0006184 143 0.216
regulation of t cell proliferation GO:0042129 92 0.216
regulation of lymphocyte activation GO:0051249 240 0.214
lymphocyte homeostasis GO:0002260 64 0.211
regulation of gtp catabolic process GO:0033124 113 0.210
guanosine containing compound metabolic process GO:1901068 144 0.210
negative regulation of protein metabolic process GO:0051248 282 0.208
regulation of ion transport GO:0043269 215 0.206
purine nucleoside triphosphate catabolic process GO:0009146 203 0.206
t cell activation GO:0042110 289 0.204
Mouse
purine ribonucleotide metabolic process GO:0009150 290 0.201
regulation of b cell proliferation GO:0030888 39 0.198
nucleobase containing small molecule metabolic process GO:0055086 352 0.197
cytosolic calcium ion transport GO:0060401 48 0.196
regulation of cellular amino acid metabolic process GO:0006521 5 0.195
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.194
purine nucleoside triphosphate metabolic process GO:0009144 226 0.191
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.181
nucleoside phosphate metabolic process GO:0006753 338 0.180
b cell homeostasis GO:0001782 34 0.179
t cell differentiation in thymus GO:0033077 77 0.176
purine ribonucleotide catabolic process GO:0009154 208 0.176
gtp metabolic process GO:0046039 144 0.174
positive regulation of b cell proliferation GO:0030890 24 0.172
guanosine containing compound catabolic process GO:1901069 144 0.167
nucleotide metabolic process GO:0009117 332 0.165
regulation of cellular amine metabolic process GO:0033238 20 0.159
nucleoside catabolic process GO:0009164 206 0.158
cellular lipid metabolic process GO:0044255 323 0.157
cellular metal ion homeostasis GO:0006875 151 0.155
cellular chemical homeostasis GO:0055082 215 0.155
positive regulation of nucleotide catabolic process GO:0030813 88 0.153
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.152
cation transport GO:0006812 399 0.152
heterocycle catabolic process GO:0046700 280 0.152
amine metabolic process GO:0009308 45 0.152
positive regulation of cellular catabolic process GO:0031331 148 0.151
negative regulation of cellular amine metabolic process GO:0033239 1 0.151
purine nucleotide metabolic process GO:0006163 302 0.149
positive regulation of t cell activation GO:0050870 101 0.146
Mouse
regulation of t cell activation GO:0050863 170 0.145
Mouse
adaptive immune response GO:0002250 155 0.143
negative regulation of protein phosphorylation GO:0001933 126 0.142
positive regulation of cell migration GO:0030335 109 0.140
sequestering of calcium ion GO:0051208 18 0.140
regulation of nucleoside metabolic process GO:0009118 130 0.138
purine nucleoside metabolic process GO:0042278 241 0.138
ribonucleoside triphosphate metabolic process GO:0009199 220 0.137
positive regulation of mapk cascade GO:0043410 170 0.135
purine nucleotide catabolic process GO:0006195 211 0.134
purine containing compound metabolic process GO:0072521 311 0.133
actin cytoskeleton organization GO:0030036 220 0.132
regulation of cytokine biosynthetic process GO:0042035 59 0.132
rho protein signal transduction GO:0007266 32 0.132
b cell differentiation GO:0030183 78 0.131
leukocyte homeostasis GO:0001776 79 0.130
regulation of purine nucleotide metabolic process GO:1900542 169 0.130
purine containing compound catabolic process GO:0072523 213 0.128
nucleotide catabolic process GO:0009166 217 0.126
sphingolipid metabolic process GO:0006665 45 0.125
carbohydrate derivative catabolic process GO:1901136 231 0.124
cellular amino acid metabolic process GO:0006520 103 0.123
cation homeostasis GO:0055080 212 0.123
t cell receptor signaling pathway GO:0050852 46 0.120
cellular nitrogen compound catabolic process GO:0044270 280 0.119
positive t cell selection GO:0043368 23 0.119
positive regulation of gtp catabolic process GO:0033126 85 0.119
glycosyl compound metabolic process GO:1901657 246 0.118
regulation of establishment of protein localization GO:0070201 181 0.117
cellular response to acid chemical GO:0071229 68 0.117
positive regulation of cytokine biosynthetic process GO:0042108 40 0.116
aromatic compound catabolic process GO:0019439 286 0.116
nucleoside phosphate catabolic process GO:1901292 222 0.115
regulation of cellular ketone metabolic process GO:0010565 66 0.115
calcium ion transport GO:0006816 159 0.115
epithelial tube morphogenesis GO:0060562 303 0.113
ribose phosphate metabolic process GO:0019693 291 0.112
positive regulation of lymphocyte activation GO:0051251 140 0.111
Mouse
positive regulation of cytokine production GO:0001819 174 0.109
regulation of protein localization GO:0032880 231 0.109
cytokine biosynthetic process GO:0042089 68 0.108
small gtpase mediated signal transduction GO:0007264 97 0.108
regulation of interleukin 2 biosynthetic process GO:0045076 13 0.107
positive regulation of lymphocyte proliferation GO:0050671 70 0.107
purine ribonucleoside catabolic process GO:0046130 205 0.106
purine ribonucleoside metabolic process GO:0046128 241 0.105
germ cell development GO:0007281 185 0.102
divalent metal ion transport GO:0070838 172 0.102
cellular calcium ion homeostasis GO:0006874 119 0.101
negative regulation of lymphocyte activation GO:0051250 91 0.101
calcium ion transport into cytosol GO:0060402 48 0.100
interferon gamma production GO:0032609 67 0.099
regulation of membrane potential GO:0042391 192 0.099
organic hydroxy compound metabolic process GO:1901615 203 0.097
positive regulation of nucleoside metabolic process GO:0045979 91 0.096
cellular ion homeostasis GO:0006873 165 0.096
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.094
positive regulation of cell activation GO:0050867 158 0.093
Mouse
ribonucleotide catabolic process GO:0009261 208 0.092
hematopoietic progenitor cell differentiation GO:0002244 143 0.090
retina development in camera type eye GO:0060041 119 0.090
Mouse
regulation of nucleotide catabolic process GO:0030811 122 0.090
innate immune response GO:0045087 157 0.089
maintenance of location GO:0051235 89 0.088
metal ion homeostasis GO:0055065 189 0.087
positive regulation of striated muscle cell differentiation GO:0051155 35 0.087
positive regulation of cell development GO:0010720 237 0.087
regulation of hydrolase activity GO:0051336 246 0.086
positive regulation of hydrolase activity GO:0051345 148 0.086
sequestering of metal ion GO:0051238 19 0.086
negative regulation of cell proliferation GO:0008285 296 0.085
ras protein signal transduction GO:0007265 77 0.085
interleukin 10 secretion GO:0072608 4 0.085
camera type eye development GO:0043010 266 0.084
Mouse
negative regulation of cellular protein metabolic process GO:0032269 247 0.084
negative regulation of growth GO:0045926 99 0.084
negative regulation of homeostatic process GO:0032845 71 0.084
regulation of secretion by cell GO:1903530 249 0.084
response to organic cyclic compound GO:0014070 198 0.083
glial cell apoptotic process GO:0034349 3 0.082
regulation of secretion GO:0051046 274 0.082
nucleoside metabolic process GO:0009116 246 0.081
positive regulation of adaptive immune response GO:0002821 61 0.080
negative regulation of molecular function GO:0044092 258 0.079
endocytosis GO:0006897 168 0.079
ribonucleoside metabolic process GO:0009119 245 0.078
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.077
divalent inorganic cation transport GO:0072511 178 0.077
mapk cascade GO:0000165 281 0.077
nucleoside triphosphate metabolic process GO:0009141 230 0.076
skin development GO:0043588 220 0.075
alpha beta t cell activation GO:0046631 91 0.075
Mouse
regulation of response to wounding GO:1903034 189 0.075
positive regulation of ion transport GO:0043270 65 0.073
lymphocyte apoptotic process GO:0070227 54 0.073
defense response to other organism GO:0098542 197 0.073
glycoprotein biosynthetic process GO:0009101 89 0.072
membrane organization GO:0061024 245 0.072
regulation of lymphocyte anergy GO:0002911 4 0.071
glycoprotein metabolic process GO:0009100 116 0.071
regulation of toll like receptor 4 signaling pathway GO:0034143 4 0.071
response to organonitrogen compound GO:0010243 246 0.071
forebrain development GO:0030900 302 0.071
Mouse
regulation of innate immune response GO:0045088 91 0.071
peptidyl amino acid modification GO:0018193 336 0.070
ribonucleotide metabolic process GO:0009259 291 0.070
regulation of interleukin 2 production GO:0032663 28 0.070
positive regulation of defense response GO:0031349 124 0.070
positive regulation of innate immune response GO:0045089 80 0.069
regulation of b cell differentiation GO:0045577 23 0.069
negative regulation of protein modification process GO:0031400 163 0.068
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.068
negative regulation of t cell activation GO:0050868 65 0.068
regulation of skeletal muscle fiber development GO:0048742 36 0.067
vesicle organization GO:0016050 60 0.067
dephosphorylation GO:0016311 129 0.066
morphogenesis of a branching epithelium GO:0061138 193 0.065
regulation of cell activation GO:0050865 289 0.065
homeostasis of number of cells GO:0048872 210 0.064
posttranscriptional regulation of gene expression GO:0010608 155 0.064
developmental maturation GO:0021700 193 0.064
cellular homeostasis GO:0019725 240 0.063
membrane lipid metabolic process GO:0006643 53 0.063
positive regulation of neuron differentiation GO:0045666 141 0.063
regulation of interferon gamma production GO:0032649 57 0.062
cytokine production GO:0001816 319 0.062
regulation of purine nucleotide catabolic process GO:0033121 122 0.061
epidermis development GO:0008544 187 0.060
protein secretion GO:0009306 111 0.060
negative regulation of b cell activation GO:0050869 27 0.059
humoral immune response GO:0006959 57 0.058
regulation of anatomical structure size GO:0090066 178 0.058
response to molecule of bacterial origin GO:0002237 143 0.058
regulation of cytoplasmic transport GO:1903649 112 0.057
gland development GO:0048732 330 0.057
Mouse
negative regulation of cell growth GO:0030308 44 0.057
positive regulation of t cell proliferation GO:0042102 52 0.056
divalent inorganic cation homeostasis GO:0072507 138 0.056
cytosolic calcium ion homeostasis GO:0051480 70 0.056
anatomical structure homeostasis GO:0060249 145 0.056
negative regulation of b cell receptor signaling pathway GO:0050859 4 0.055
axonogenesis GO:0007409 274 0.055
histamine production involved in inflammatory response GO:0002349 1 0.055
regulation of cytokine production GO:0001817 266 0.055
regulation of b cell apoptotic process GO:0002902 13 0.054
cellular response to lipopolysaccharide GO:0071222 77 0.053
regulation of ion homeostasis GO:2000021 64 0.053
multicellular organism growth GO:0035264 161 0.053
Mouse
regulation of lymphocyte differentiation GO:0045619 107 0.053
protein localization to organelle GO:0033365 185 0.053
negative regulation of protein processing GO:0010955 79 0.053
branching involved in ureteric bud morphogenesis GO:0001658 56 0.053
male gamete generation GO:0048232 285 0.051
type i interferon production GO:0032606 29 0.051
cell type specific apoptotic process GO:0097285 268 0.051
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.050
establishment of protein localization to organelle GO:0072594 118 0.050
positive regulation of smooth muscle cell migration GO:0014911 4 0.050
regulation of defense response GO:0031347 233 0.050
single organism cell adhesion GO:0098602 156 0.049
regulation of germinal center formation GO:0002634 10 0.049
regulation of cell motility GO:2000145 236 0.049
negative regulation of phosphorylation GO:0042326 166 0.049
cerebral cortex development GO:0021987 86 0.049
regulation of nucleotide metabolic process GO:0006140 169 0.048
cytoplasmic transport GO:0016482 234 0.048
response to reactive oxygen species GO:0000302 56 0.048
calcium ion homeostasis GO:0055074 127 0.047
morphogenesis of a branching structure GO:0001763 203 0.047
telencephalon development GO:0021537 186 0.047
membrane fusion GO:0061025 38 0.047
regulation of neuron differentiation GO:0045664 281 0.047
regulation of nitrogen utilization GO:0006808 2 0.047
t cell costimulation GO:0031295 14 0.046
negative regulation of neuron death GO:1901215 98 0.045
extracellular matrix organization GO:0030198 147 0.045
regulation of protein transport GO:0051223 163 0.045
organelle assembly GO:0070925 177 0.044
cytokine secretion GO:0050663 72 0.044
necrotic cell death GO:0070265 30 0.044
mammary gland epithelium development GO:0061180 65 0.044
glycosphingolipid metabolic process GO:0006687 18 0.044
regulation of map kinase activity GO:0043405 120 0.044
lipid transport GO:0006869 98 0.044
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.044
regulation of metal ion transport GO:0010959 106 0.044
negative regulation of anoikis GO:2000811 2 0.044
cellular response to amino acid stimulus GO:0071230 29 0.044
regulation of cellular catabolic process GO:0031329 242 0.044
regulation of protein secretion GO:0050708 82 0.043
inflammatory response GO:0006954 244 0.043
cell adhesion GO:0007155 329 0.043
regulation of protein kinase activity GO:0045859 232 0.043
response to lipopolysaccharide GO:0032496 128 0.043
positive regulation of nucleotide metabolic process GO:0045981 114 0.043
regulation of body fluid levels GO:0050878 162 0.043
lymphocyte mediated immunity GO:0002449 139 0.042
negative regulation of organelle organization GO:0010639 90 0.042
kidney epithelium development GO:0072073 121 0.042
cytokine metabolic process GO:0042107 71 0.041
anion transport GO:0006820 177 0.041
interleukin 5 secretion GO:0072603 2 0.041
cell substrate adhesion GO:0031589 130 0.041
regulation of organelle organization GO:0033043 289 0.041
b cell apoptotic process GO:0001783 19 0.041
positive regulation of interferon gamma biosynthetic process GO:0045078 4 0.041
lipopolysaccharide mediated signaling pathway GO:0031663 25 0.041
regulation of peptide hormone secretion GO:0090276 75 0.041
protein maturation GO:0051604 176 0.041
peptidyl threonine modification GO:0018210 31 0.041
cellular macromolecule catabolic process GO:0044265 206 0.040
tissue remodeling GO:0048771 102 0.040
sensory perception GO:0007600 245 0.040
defense response to gram positive bacterium GO:0050830 50 0.040
positive regulation of interferon alpha production GO:0032727 4 0.039
positive regulation of cell death GO:0010942 224 0.039
negative regulation of cell activation GO:0050866 111 0.039
carbohydrate derivative biosynthetic process GO:1901137 183 0.039
spleen development GO:0048536 39 0.039
regulation of organ morphogenesis GO:2000027 144 0.039
cell division GO:0051301 120 0.039
cd4 positive or cd8 positive alpha beta t cell lineage commitment GO:0043369 8 0.038
coagulation GO:0050817 78 0.038
programmed necrotic cell death GO:0097300 28 0.037
negative regulation of leukocyte differentiation GO:1902106 51 0.037
renal tubule development GO:0061326 87 0.037
positive regulation of homeostatic process GO:0032846 64 0.037
positive regulation of peptidyl serine phosphorylation GO:0033138 25 0.037
regulation of tumor necrosis factor biosynthetic process GO:0042534 10 0.037
female gamete generation GO:0007292 74 0.037
defense response to bacterium GO:0042742 119 0.037
positive regulation of protein modification process GO:0031401 299 0.036
pigment metabolic process GO:0042440 32 0.036
response to growth factor GO:0070848 198 0.036
cell maturation GO:0048469 127 0.036
apoptotic signaling pathway GO:0097190 306 0.036
dendritic cell differentiation GO:0097028 26 0.036
spermatid differentiation GO:0048515 115 0.036
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.036
cellular response to oxidative stress GO:0034599 76 0.036
positive regulation of podosome assembly GO:0071803 3 0.036
myd88 independent toll like receptor signaling pathway GO:0002756 3 0.035
positive regulation of organelle organization GO:0010638 128 0.035
regulation of monocyte extravasation GO:2000437 2 0.035
regulation of leukocyte differentiation GO:1902105 159 0.035
leukocyte mediated immunity GO:0002443 174 0.034
cellular response to gamma radiation GO:0071480 4 0.034
response to amino acid GO:0043200 37 0.034
regulation of intracellular transport GO:0032386 159 0.034
phospholipid metabolic process GO:0006644 87 0.034
cellular response to external stimulus GO:0071496 88 0.034
b cell activation involved in immune response GO:0002312 50 0.034
interleukin 12 production GO:0032615 32 0.034
regulation of dendritic cell chemotaxis GO:2000508 1 0.034
cytokine mediated signaling pathway GO:0019221 115 0.033
secondary metabolic process GO:0019748 18 0.033
regulation of apoptotic signaling pathway GO:2001233 197 0.033
nephron development GO:0072006 109 0.033
positive regulation of nervous system development GO:0051962 221 0.033
response to peptide GO:1901652 136 0.033
wnt signaling pathway GO:0016055 188 0.033
regulation of cell adhesion GO:0030155 154 0.033
t cell homeostatic proliferation GO:0001777 4 0.033
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:0097296 2 0.033
regulation of cell cycle GO:0051726 281 0.033
cell chemotaxis GO:0060326 81 0.033
cellular response to molecule of fungal origin GO:0071226 2 0.033
cellular response to lipid GO:0071396 145 0.033
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.032
lymphocyte anergy GO:0002249 4 0.032
tissue homeostasis GO:0001894 115 0.032
ossification GO:0001503 216 0.032
regulation of t cell receptor signaling pathway GO:0050856 21 0.032
positive regulation of pigment cell differentiation GO:0050942 5 0.032
regulation of leukocyte apoptotic process GO:2000106 56 0.032
regulation of homotypic cell cell adhesion GO:0034110 13 0.032
synaptic transmission GO:0007268 329 0.032
neuron apoptotic process GO:0051402 142 0.031
regulation of cell substrate adhesion GO:0010810 73 0.031
regulation of protein processing GO:0070613 96 0.031
male gonad development GO:0008584 88 0.031
chromatin modification GO:0016568 187 0.031
regulation of protein maturation GO:1903317 96 0.031
mammary gland epithelial cell proliferation GO:0033598 24 0.031
nuclear division GO:0000280 158 0.031
regulation of reactive oxygen species metabolic process GO:2000377 40 0.030
cellular protein catabolic process GO:0044257 155 0.030
regulation of peptidyl serine phosphorylation GO:0033135 39 0.030
organ growth GO:0035265 117 0.030
regulation of striated muscle cell differentiation GO:0051153 81 0.030
cellular response to molecule of bacterial origin GO:0071219 83 0.029
cellular response to extracellular stimulus GO:0031668 81 0.029
g1 s transition of mitotic cell cycle GO:0000082 57 0.029
digestive tract development GO:0048565 190 0.029
regulation of alpha beta t cell activation GO:0046634 53 0.029
Mouse
regulation of lymphocyte apoptotic process GO:0070228 41 0.029
positive regulation of leukocyte apoptotic process GO:2000108 21 0.029
regulation of ras gtpase activity GO:0032318 88 0.029
protein insertion into mitochondrial membrane involved in apoptotic signaling pathway GO:0001844 4 0.029
regulation of homeostatic process GO:0032844 182 0.029
negative regulation of proteolysis GO:0045861 74 0.029
modification dependent protein catabolic process GO:0019941 133 0.029
renal system development GO:0072001 225 0.029
regulation of neuron apoptotic process GO:0043523 122 0.029
response to osmotic stress GO:0006970 21 0.029
positive regulation of ras gtpase activity GO:0032320 65 0.028
extrinsic apoptotic signaling pathway GO:0097191 126 0.028
covalent chromatin modification GO:0016569 163 0.028
muscle cell differentiation GO:0042692 261 0.028
regulation of cell cycle process GO:0010564 160 0.028
skeletal muscle organ development GO:0060538 163 0.028
mitochondrial fusion GO:0008053 9 0.028
nitrogen compound transport GO:0071705 271 0.028
positive regulation of protein phosphorylation GO:0001934 242 0.028
negative regulation of regulatory t cell differentiation GO:0045590 2 0.028
mast cell proliferation GO:0070662 4 0.028
osteoclast differentiation GO:0030316 62 0.028
muscle fiber development GO:0048747 76 0.028
organelle fission GO:0048285 170 0.028
peptidyl lysine modification GO:0018205 77 0.028
cellular response to biotic stimulus GO:0071216 92 0.027
histamine transport GO:0051608 2 0.027
myeloid cell homeostasis GO:0002262 114 0.027
striated muscle cell development GO:0055002 125 0.027
regulation of interleukin 4 biosynthetic process GO:0045402 3 0.027
protein ubiquitination GO:0016567 171 0.027
negative regulation of apoptotic signaling pathway GO:2001234 104 0.027
carbohydrate homeostasis GO:0033500 128 0.027
regulation of alpha beta t cell proliferation GO:0046640 18 0.027
kidney development GO:0001822 213 0.027
renal tubule morphogenesis GO:0061333 72 0.027
protein processing GO:0016485 163 0.027
multicellular organismal homeostasis GO:0048871 164 0.027
endomembrane system organization GO:0010256 147 0.026
positive regulation of interferon gamma production GO:0032729 39 0.026
mitotic cell cycle GO:0000278 195 0.026
male sex differentiation GO:0046661 109 0.026
regulation of myeloid cell differentiation GO:0045637 96 0.026
Mouse
immune response inhibiting signal transduction GO:0002765 4 0.026
regulation of interleukin 8 secretion GO:2000482 2 0.026
positive regulation of rac gtpase activity GO:0032855 14 0.026
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.026
negative regulation of lymphocyte proliferation GO:0050672 45 0.026
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.026
negative regulation of intracellular signal transduction GO:1902532 167 0.026
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.026
branching morphogenesis of an epithelial tube GO:0048754 159 0.026
pallium development GO:0021543 120 0.026
regulation of inflammatory response GO:0050727 147 0.026
interspecies interaction between organisms GO:0044419 83 0.026
t cell apoptotic process GO:0070231 39 0.026
negative regulation of cellular component organization GO:0051129 194 0.026
regulation of transferase activity GO:0051338 263 0.026
regulation of cell projection organization GO:0031344 206 0.026
intracellular protein transport GO:0006886 204 0.025
actin filament polymerization GO:0030041 44 0.025
leukocyte migration GO:0050900 124 0.025
regulation of cell migration GO:0030334 219 0.025
chromatin organization GO:0006325 206 0.025
monosaccharide transport GO:0015749 58 0.025
myeloid cell activation involved in immune response GO:0002275 34 0.025
regulation of actin cytoskeleton organization GO:0032956 84 0.025
lymphocyte costimulation GO:0031294 15 0.025
positive regulation of immune effector process GO:0002699 107 0.025
extracellular structure organization GO:0043062 148 0.025
regulation of stress activated mapk cascade GO:0032872 69 0.025
single organismal cell cell adhesion GO:0016337 131 0.025
digestive system development GO:0055123 200 0.025
developmental programmed cell death GO:0010623 41 0.025
gonad development GO:0008406 141 0.024
negative regulation of protein transport GO:0051224 46 0.024
regulation of cell growth GO:0001558 91 0.024
somatic diversification of immune receptors GO:0002200 53 0.024
protein modification by small protein conjugation GO:0032446 187 0.024
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.024
positive regulation of muscle cell differentiation GO:0051149 39 0.024
negative regulation of retinal cell programmed cell death GO:0046671 2 0.024
histone modification GO:0016570 159 0.024
liposaccharide metabolic process GO:1903509 27 0.024
regulation of cellular component size GO:0032535 121 0.024
negative regulation of cell cycle GO:0045786 123 0.024
toll like receptor signaling pathway GO:0002224 38 0.024
lipid localization GO:0010876 126 0.024
protein localization to membrane GO:0072657 108 0.024
dna metabolic process GO:0006259 303 0.023
regulation of g1 s transition of mitotic cell cycle GO:2000045 35 0.023
thymic t cell selection GO:0045061 22 0.023
protein localization to nucleus GO:0034504 121 0.023
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.023
interleukin 2 production GO:0032623 33 0.023
negative regulation of defense response GO:0031348 77 0.023
cellular response to cytokine stimulus GO:0071345 189 0.023
dendritic cell apoptotic process GO:0097048 3 0.023
cellular protein complex assembly GO:0043623 116 0.023
methylation GO:0032259 134 0.023
positive regulation of kinase activity GO:0033674 155 0.023
regulation of anoikis GO:2000209 2 0.023
kidney morphogenesis GO:0060993 83 0.023
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.023
regulation of interleukin 6 production GO:0032675 55 0.023
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 34 0.023
regulation of dendritic cell apoptotic process GO:2000668 3 0.023
regulation of neuron death GO:1901214 134 0.023
regulation of hormone levels GO:0010817 211 0.023
protein oligomerization GO:0051259 67 0.023
cellular divalent inorganic cation homeostasis GO:0072503 127 0.023
regulation of synapse structural plasticity GO:0051823 4 0.022
metencephalon development GO:0022037 89 0.022
regulation of calcium ion transport GO:0051924 69 0.022
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.022
urogenital system development GO:0001655 261 0.022

Ikzf3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.256
disease of anatomical entity DOID:7 0 0.256
hematopoietic system disease DOID:74 0 0.092
primary immunodeficiency disease DOID:612 0 0.089
b cell deficiency DOID:2115 0 0.089
blood protein disease DOID:620 0 0.087
agammaglobulinemia DOID:2583 0 0.039
common variable immunodeficiency DOID:12177 0 0.035
disease of metabolism DOID:0014667 0 0.032
acquired metabolic disease DOID:0060158 0 0.032
hypersensitivity reaction disease DOID:0060056 0 0.029