Mus musculus

0 known processes

Mark4

MAP/microtubule affinity-regulating kinase 4

(Aliases: Markl1,C79806,2410090P21Rik)

Mark4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regionalization GO:0003002 337 0.928
actin cytoskeleton organization GO:0030036 220 0.883
response to peptide hormone GO:0043434 127 0.854
Mouse
neuron projection guidance GO:0097485 141 0.640
response to insulin GO:0032868 100 0.597
Mouse
response to organonitrogen compound GO:0010243 246 0.579
Mouse
actin filament organization GO:0007015 113 0.515
t cell activation GO:0042110 289 0.512
cellular response to insulin stimulus GO:0032869 78 0.503
Mouse
gtp metabolic process GO:0046039 144 0.492
mitotic cell cycle GO:0000278 195 0.480
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.460
Mouse
gtp catabolic process GO:0006184 143 0.454
positive regulation of gtpase activity GO:0043547 85 0.449
negative regulation of protein metabolic process GO:0051248 282 0.428
axonogenesis GO:0007409 274 0.401
response to peptide GO:1901652 136 0.382
Mouse
guanosine containing compound metabolic process GO:1901068 144 0.369
peptidyl serine modification GO:0018209 83 0.369
Worm
protein localization to membrane GO:0072657 108 0.360
macromolecule catabolic process GO:0009057 281 0.344
regulation of carbohydrate biosynthetic process GO:0043255 40 0.344
Mouse
regulation of neurotransmitter levels GO:0001505 87 0.342
regulation of ras gtpase activity GO:0032318 88 0.337
carbohydrate biosynthetic process GO:0016051 74 0.336
Mouse
cellular response to organonitrogen compound GO:0071417 145 0.319
Mouse
dendrite development GO:0016358 115 0.317
guanosine containing compound catabolic process GO:1901069 144 0.310
germ cell development GO:0007281 185 0.309
aromatic compound catabolic process GO:0019439 286 0.287
purine nucleoside metabolic process GO:0042278 241 0.286
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.285
t cell differentiation GO:0030217 174 0.285
ras protein signal transduction GO:0007265 77 0.265
organelle assembly GO:0070925 177 0.256
nucleoside triphosphate metabolic process GO:0009141 230 0.253
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.252
Mouse
respiratory tube development GO:0030323 167 0.250
positive regulation of cellular amine metabolic process GO:0033240 5 0.250
cell adhesion GO:0007155 329 0.249
cellular ketone metabolic process GO:0042180 84 0.249
Mouse
cell type specific apoptotic process GO:0097285 268 0.245
negative regulation of cellular protein metabolic process GO:0032269 247 0.241
synapse assembly GO:0007416 56 0.241
regulation of cell activation GO:0050865 289 0.239
cellular component assembly involved in morphogenesis GO:0010927 139 0.239
establishment of protein localization to membrane GO:0090150 54 0.230
axon guidance GO:0007411 141 0.229
chemotaxis GO:0006935 247 0.227
carbohydrate derivative catabolic process GO:1901136 231 0.226
lymphocyte differentiation GO:0030098 242 0.225
positive regulation of gtp catabolic process GO:0033126 85 0.203
cell fate commitment GO:0045165 210 0.201
Worm
carbohydrate metabolic process GO:0005975 230 0.200
Mouse
regulation of glutamate receptor signaling pathway GO:1900449 16 0.200
mapk cascade GO:0000165 281 0.196
nucleoside triphosphate catabolic process GO:0009143 205 0.196
nucleobase containing small molecule metabolic process GO:0055086 352 0.196
regulation of t cell activation GO:0050863 170 0.194
small gtpase mediated signal transduction GO:0007264 97 0.192
regulation of system process GO:0044057 200 0.191
hexose biosynthetic process GO:0019319 39 0.191
Mouse
regulation of carbohydrate metabolic process GO:0006109 75 0.190
Mouse
purine ribonucleotide metabolic process GO:0009150 290 0.189
regulation of secretion GO:0051046 274 0.189
development of primary sexual characteristics GO:0045137 143 0.189
Worm
regulation of cardioblast differentiation GO:0051890 3 0.186
embryonic epithelial tube formation GO:0001838 130 0.183
regulation of organelle organization GO:0033043 289 0.179
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.179
synapse organization GO:0050808 125 0.175
monosaccharide metabolic process GO:0005996 106 0.174
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.173
t cell differentiation in thymus GO:0033077 77 0.173
amine metabolic process GO:0009308 45 0.172
negative regulation of protein phosphorylation GO:0001933 126 0.171
peptidyl serine phosphorylation GO:0018105 74 0.170
Worm
regulation of neuron differentiation GO:0045664 281 0.169
rho protein signal transduction GO:0007266 32 0.169
regulation of cellular amine metabolic process GO:0033238 20 0.167
stem cell development GO:0048864 219 0.163
regulation of actin cytoskeleton organization GO:0032956 84 0.162
peptidyl amino acid modification GO:0018193 336 0.161
Worm
negative regulation of cell proliferation GO:0008285 296 0.161
heart induction GO:0003129 2 0.156
forebrain development GO:0030900 302 0.153
neurotransmitter transport GO:0006836 76 0.153
alpha beta t cell differentiation GO:0046632 69 0.152
positive regulation of protein modification process GO:0031401 299 0.152
purine containing compound metabolic process GO:0072521 311 0.152
myeloid cell differentiation GO:0030099 233 0.149
cell matrix adhesion GO:0007160 68 0.149
blood circulation GO:0008015 195 0.148
nucleoside phosphate metabolic process GO:0006753 338 0.148
leukocyte differentiation GO:0002521 342 0.147
multi multicellular organism process GO:0044706 109 0.146
gland development GO:0048732 330 0.145
regulation of cytoskeleton organization GO:0051493 122 0.144
regulation of neuron projection development GO:0010975 169 0.140
endocytosis GO:0006897 168 0.140
cation transport GO:0006812 399 0.140
protein catabolic process GO:0030163 221 0.138
negative regulation of cell motility GO:2000146 61 0.137
purine nucleoside triphosphate catabolic process GO:0009146 203 0.137
neurotransmitter secretion GO:0007269 62 0.137
canonical wnt signaling pathway involved in heart development GO:0061316 3 0.136
lipid biosynthetic process GO:0008610 179 0.135
Mouse
regulation of cellular catabolic process GO:0031329 242 0.135
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.134
Mouse
cellular response to peptide GO:1901653 92 0.133
Mouse
cell substrate adhesion GO:0031589 130 0.132
muscle cell differentiation GO:0042692 261 0.132
Mouse
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.124
positive regulation of cell activation GO:0050867 158 0.124
organophosphate catabolic process GO:0046434 232 0.124
regulation of insulin receptor signaling pathway GO:0046626 21 0.123
Mouse
cellular nitrogen compound catabolic process GO:0044270 280 0.123
cerebral cortex radially oriented cell migration GO:0021799 31 0.122
nucleoside metabolic process GO:0009116 246 0.122
cerebral cortex cell migration GO:0021795 44 0.121
cd4 positive alpha beta t cell activation GO:0035710 45 0.120
nucleoside catabolic process GO:0009164 206 0.120
positive regulation of ras gtpase activity GO:0032320 65 0.119
blood vessel morphogenesis GO:0048514 285 0.119
oogenesis GO:0048477 56 0.118
regulation of lymphocyte activation GO:0051249 240 0.115
female gamete generation GO:0007292 74 0.114
developmental maturation GO:0021700 193 0.114
cellular response to hormone stimulus GO:0032870 150 0.113
Mouse
membrane organization GO:0061024 245 0.111
cellular amino acid metabolic process GO:0006520 103 0.111
fat cell differentiation GO:0045444 160 0.109
central nervous system neuron differentiation GO:0021953 162 0.109
ribonucleoside triphosphate catabolic process GO:0009203 199 0.109
regulation of vesicle mediated transport GO:0060627 139 0.109
phospholipid metabolic process GO:0006644 87 0.108
cellular response to dna damage stimulus GO:0006974 207 0.108
maintenance of location GO:0051235 89 0.108
regulation of fibroblast proliferation GO:0048145 34 0.108
stem cell maintenance GO:0019827 130 0.107
meiotic cell cycle GO:0051321 122 0.106
regulation of cellular amino acid metabolic process GO:0006521 5 0.105
regulation of fat cell differentiation GO:0045598 81 0.105
single organismal cell cell adhesion GO:0016337 131 0.105
regulation of rho gtpase activity GO:0032319 58 0.104
segmentation GO:0035282 93 0.103
stem cell differentiation GO:0048863 268 0.103
regulation of secretion by cell GO:1903530 249 0.102
response to radiation GO:0009314 165 0.101
Mouse
apoptotic signaling pathway GO:0097190 306 0.101
purine ribonucleotide catabolic process GO:0009154 208 0.100
dna metabolic process GO:0006259 303 0.100
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.100
ribonucleoside metabolic process GO:0009119 245 0.099
regulation of leukocyte differentiation GO:1902105 159 0.099
purine nucleotide metabolic process GO:0006163 302 0.099
negative regulation of protein modification process GO:0031400 163 0.099
cardiocyte differentiation GO:0035051 87 0.099
Mouse
telencephalon cell migration GO:0022029 55 0.099
protein localization to plasma membrane GO:0072659 57 0.098
lung development GO:0030324 164 0.097
cellular homeostasis GO:0019725 240 0.097
positive regulation of secretion GO:0051047 130 0.097
urogenital system development GO:0001655 261 0.097
neural precursor cell proliferation GO:0061351 121 0.096
Worm
alpha beta t cell activation GO:0046631 91 0.096
male gamete generation GO:0048232 285 0.096
regulation of myeloid cell differentiation GO:0045637 96 0.095
lipid catabolic process GO:0016042 69 0.095
regulation of transferase activity GO:0051338 263 0.094
organic acid transport GO:0015849 101 0.094
regulation of cell shape GO:0008360 39 0.093
organelle localization GO:0051640 179 0.093
development of primary male sexual characteristics GO:0046546 88 0.093
regulation of reproductive process GO:2000241 66 0.092
regulation of cell migration GO:0030334 219 0.092
glycosyl compound metabolic process GO:1901657 246 0.092
positive regulation of cell development GO:0010720 237 0.091
cellular amine metabolic process GO:0044106 44 0.091
respiratory system development GO:0060541 190 0.091
negative regulation of immune system process GO:0002683 209 0.091
cilium morphogenesis GO:0060271 102 0.089
purine containing compound catabolic process GO:0072523 213 0.089
positive regulation of cellular catabolic process GO:0031331 148 0.089
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.088
organophosphate biosynthetic process GO:0090407 122 0.088
muscle tissue development GO:0060537 308 0.087
Mouse
negative regulation of lipid metabolic process GO:0045833 30 0.087
Mouse
autophagy GO:0006914 45 0.087
primary neural tube formation GO:0014020 95 0.087
morphogenesis of a polarized epithelium GO:0001738 37 0.086
positive regulation of mapk cascade GO:0043410 170 0.085
cell maturation GO:0048469 127 0.084
cellular chemical homeostasis GO:0055082 215 0.084
vesicle organization GO:0016050 60 0.084
methylation GO:0032259 134 0.083
regulation of ras protein signal transduction GO:0046578 114 0.083
endomembrane system organization GO:0010256 147 0.082
regulation of neuron apoptotic process GO:0043523 122 0.082
regulation of cell adhesion GO:0030155 154 0.082
neural tube closure GO:0001843 90 0.082
regulation of synapse assembly GO:0051963 29 0.081
microtubule cytoskeleton organization GO:0000226 157 0.080
Human
regulation of lymphocyte differentiation GO:0045619 107 0.080
regulation of neuron death GO:1901214 134 0.080
compound eye development GO:0048749 1 0.079
male sex differentiation GO:0046661 109 0.079
regulation of protein serine threonine kinase activity GO:0071900 157 0.079
positive regulation of rho gtpase activity GO:0032321 41 0.079
regulation of cell projection organization GO:0031344 206 0.079
fibroblast migration GO:0010761 21 0.078
response to light stimulus GO:0009416 135 0.077
Mouse
ribonucleotide catabolic process GO:0009261 208 0.077
amide transport GO:0042886 138 0.077
gonadotrophin releasing hormone neuronal migration to the hypothalamus GO:0021828 3 0.077
ribose phosphate metabolic process GO:0019693 291 0.076
positive regulation of nervous system development GO:0051962 221 0.075
negative regulation of phosphate metabolic process GO:0045936 184 0.075
oocyte differentiation GO:0009994 35 0.075
positive regulation of growth GO:0045927 104 0.075
positive regulation of cellular component biogenesis GO:0044089 94 0.074
ribonucleoprotein complex disassembly GO:0032988 3 0.074
regulation of peptide hormone secretion GO:0090276 75 0.073
neural crest cell migration involved in sympathetic nervous system development GO:1903045 1 0.073
ribonucleoside triphosphate metabolic process GO:0009199 220 0.072
microtubule based process GO:0007017 236 0.071
Human
regulation of cellular component biogenesis GO:0044087 181 0.071
regulation of gtp catabolic process GO:0033124 113 0.071
purine ribonucleoside catabolic process GO:0046130 205 0.071
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.071
heterocycle catabolic process GO:0046700 280 0.071
organonitrogen compound catabolic process GO:1901565 264 0.070
glycosyl compound catabolic process GO:1901658 206 0.069
pallium development GO:0021543 120 0.069
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.068
regulation of cell cycle GO:0051726 281 0.068
Mouse
oocyte development GO:0048599 33 0.067
morphogenesis of embryonic epithelium GO:0016331 159 0.067
positive regulation of glucose transport GO:0010828 16 0.067
t cell proliferation GO:0042098 120 0.067
positive regulation of organelle organization GO:0010638 128 0.066
positive regulation of nucleotide catabolic process GO:0030813 88 0.065
telencephalon development GO:0021537 186 0.064
engulfment of apoptotic cell GO:0043652 3 0.064
regulation of heart contraction GO:0008016 77 0.064
embryonic organ morphogenesis GO:0048562 276 0.064
regulation of cell motility GO:2000145 236 0.063
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.063
establishment of protein localization to plasma membrane GO:0090002 34 0.063
directional locomotion GO:0033058 3 0.063
negative regulation of cell growth GO:0030308 44 0.063
nucleotide metabolic process GO:0009117 332 0.063
single organism cell adhesion GO:0098602 156 0.062
meiotic nuclear division GO:0007126 115 0.062
ribonucleoside catabolic process GO:0042454 206 0.062
negative regulation of cell migration GO:0030336 59 0.062
posttranscriptional regulation of gene expression GO:0010608 155 0.061
antimicrobial peptide production GO:0002775 2 0.061
cellular lipid metabolic process GO:0044255 323 0.061
Mouse
cytokine production GO:0001816 319 0.060
negative regulation of leukocyte differentiation GO:1902106 51 0.059
angiogenesis GO:0001525 201 0.059
organic hydroxy compound metabolic process GO:1901615 203 0.059
regulation of purine nucleotide metabolic process GO:1900542 169 0.059
appendage development GO:0048736 166 0.059
Mouse
microtubule based movement GO:0007018 84 0.058
carbohydrate derivative biosynthetic process GO:1901137 183 0.058
cerebellar granule cell precursor tangential migration GO:0021935 1 0.058
mitotic cell cycle process GO:1903047 159 0.058
establishment of synaptic vesicle localization GO:0097480 57 0.058
immune effector process GO:0002252 321 0.057
cartilage development GO:0051216 140 0.057
Mouse
mrna transcription from rna polymerase ii promoter GO:0042789 4 0.057
erythrocyte differentiation GO:0030218 88 0.056
regulation of feeding behavior GO:0060259 3 0.056
neuron apoptotic process GO:0051402 142 0.056
cellular response to peptide hormone stimulus GO:0071375 92 0.056
Mouse
regulation of nucleotide metabolic process GO:0006140 169 0.056
negative regulation of phosphorus metabolic process GO:0010563 184 0.056
synaptic vesicle transport GO:0048489 57 0.055
learning GO:0007612 98 0.055
cellular carbohydrate metabolic process GO:0044262 119 0.055
Mouse
regulation of protein kinase activity GO:0045859 232 0.054
trunk neural crest cell migration GO:0036484 4 0.054
cytoplasmic transport GO:0016482 234 0.054
regulation of cd4 positive alpha beta t cell activation GO:2000514 24 0.054
regulation of cytokine production GO:0001817 266 0.054
generation of precursor metabolites and energy GO:0006091 103 0.053
compartment pattern specification GO:0007386 4 0.053
male gonad development GO:0008584 88 0.053
learning or memory GO:0007611 148 0.053
glucose metabolic process GO:0006006 92 0.053
Mouse
lipid localization GO:0010876 126 0.053
regulation of homeostatic process GO:0032844 182 0.053
lung field specification GO:0060424 3 0.053
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.052
actomyosin structure organization GO:0031032 56 0.052
epidermis development GO:0008544 187 0.052
negative regulation of phosphorylation GO:0042326 166 0.052
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.052
myeloid cell homeostasis GO:0002262 114 0.051
protein autophosphorylation GO:0046777 61 0.051
camera type eye development GO:0043010 266 0.051
positive regulation of smooth muscle cell migration GO:0014911 4 0.051
regulation of hydrolase activity GO:0051336 246 0.051
regulation of mapk cascade GO:0043408 248 0.050
glucose homeostasis GO:0042593 128 0.050
positive regulation of transferase activity GO:0051347 167 0.050
filopodium assembly GO:0046847 19 0.050
regulation of antimicrobial humoral response GO:0002759 3 0.050
intracellular protein transport GO:0006886 204 0.049
regulation of gluconeogenesis GO:0006111 30 0.049
Mouse
nucleoside phosphate catabolic process GO:1901292 222 0.049
synaptic transmission GO:0007268 329 0.049
neural tube formation GO:0001841 108 0.049
organic cyclic compound catabolic process GO:1901361 295 0.049
muscle system process GO:0003012 141 0.049
cellular lipid catabolic process GO:0044242 52 0.049
spermatogenesis GO:0007283 284 0.049
gonad development GO:0008406 141 0.048
Worm
glycerolipid biosynthetic process GO:0045017 50 0.048
Mouse
monocarboxylic acid metabolic process GO:0032787 191 0.048
actin filament bundle assembly GO:0051017 40 0.048
purine nucleotide catabolic process GO:0006195 211 0.047
leukocyte mediated immunity GO:0002443 174 0.047
response to nutrient levels GO:0031667 109 0.047
cell cell junction organization GO:0045216 72 0.047
establishment of vesicle localization GO:0051650 81 0.047
regulation of lipid metabolic process GO:0019216 118 0.047
Mouse
positive regulation of leukocyte apoptotic process GO:2000108 21 0.046
oocyte axis specification GO:0007309 2 0.046
cell growth GO:0016049 130 0.046
regulation of peptide secretion GO:0002791 77 0.046
transforming growth factor beta2 production GO:0032906 2 0.046
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.046
positive regulation of cellular carbohydrate metabolic process GO:0010676 29 0.045
leukocyte proliferation GO:0070661 172 0.045
sympathetic neuron projection extension GO:0097490 4 0.045
regulation of mitotic cell cycle GO:0007346 126 0.045
Mouse
digestive system development GO:0055123 200 0.045
nuclear division GO:0000280 158 0.045
cellularization GO:0007349 1 0.045
regulation of neural precursor cell proliferation GO:2000177 70 0.045
protein modification by small protein conjugation GO:0032446 187 0.044
carboxylic acid transport GO:0046942 100 0.044
leukocyte homeostasis GO:0001776 79 0.044
regulation of t cell differentiation GO:0045580 83 0.044
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.044
tube formation GO:0035148 140 0.044
cerebral cortex development GO:0021987 86 0.044
female sex differentiation GO:0046660 84 0.044
positive regulation of secretion by cell GO:1903532 114 0.044
spermatid development GO:0007286 108 0.044
organelle fusion GO:0048284 28 0.044
regulation of actin filament based process GO:0032970 99 0.043
cardiac muscle tissue development GO:0048738 130 0.043
Mouse
positive regulation of carbohydrate metabolic process GO:0045913 30 0.043
negative regulation of neuron apoptotic process GO:0043524 92 0.043
mesenchymal cell development GO:0014031 93 0.043
embryonic placenta development GO:0001892 98 0.043
canonical wnt signaling pathway involved in regulation of cell proliferation GO:0044340 3 0.043
anion transport GO:0006820 177 0.042
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.042
sympathetic neuron projection guidance GO:0097491 4 0.042
response to acid chemical GO:0001101 111 0.042
regulation of body fluid levels GO:0050878 162 0.042
response to inorganic substance GO:0010035 96 0.041
neural tube development GO:0021915 160 0.041
spermatid differentiation GO:0048515 115 0.041
jnk cascade GO:0007254 72 0.041
cognition GO:0050890 149 0.041
positive regulation of posttranscriptional gene silencing GO:0060148 1 0.041
sensory organ morphogenesis GO:0090596 242 0.041
renal system development GO:0072001 225 0.041
regulation of cardiac cell fate specification GO:2000043 1 0.041
positive regulation of cell cycle GO:0045787 92 0.041
positive regulation of protein phosphorylation GO:0001934 242 0.041
response to fibroblast growth factor GO:0071774 47 0.041
regulation of leukocyte proliferation GO:0070663 121 0.041
regulation of antimicrobial peptide biosynthetic process GO:0002805 1 0.041
regulation of cellular response to stress GO:0080135 159 0.041
organelle fission GO:0048285 170 0.040
nucleotide catabolic process GO:0009166 217 0.040
nitrogen compound transport GO:0071705 271 0.040
regulation of muscle system process GO:0090257 80 0.040
immunoglobulin mediated immune response GO:0016064 69 0.040
glycoprotein metabolic process GO:0009100 116 0.040
translation GO:0006412 93 0.040
synaptic vesicle localization GO:0097479 59 0.040
positive regulation of t cell differentiation GO:0045582 52 0.040
response to organic cyclic compound GO:0014070 198 0.040
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.040
positive regulation of autophagy GO:0010508 9 0.039
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.039
purine ribonucleoside metabolic process GO:0046128 241 0.039
microtubule based transport GO:0010970 50 0.039
placenta development GO:0001890 140 0.039
epithelial tube morphogenesis GO:0060562 303 0.038
striated muscle cell development GO:0055002 125 0.038
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.038
lens development in camera type eye GO:0002088 62 0.038
peptide secretion GO:0002790 114 0.038
leukocyte apoptotic process GO:0071887 71 0.038
fatty acid metabolic process GO:0006631 121 0.037
regulation of peptidyl serine phosphorylation GO:0033135 39 0.037
neuron projection extension GO:1990138 64 0.037
circulatory system process GO:0003013 197 0.037
branching morphogenesis of an epithelial tube GO:0048754 159 0.037
negative regulation of intracellular signal transduction GO:1902532 167 0.037
skeletal muscle fiber development GO:0048741 58 0.037
muscle cell development GO:0055001 133 0.037
peptide transport GO:0015833 133 0.037
positive regulation of programmed cell death GO:0043068 218 0.037
sensory perception of touch GO:0050975 2 0.036
response to growth factor GO:0070848 198 0.036
cellular protein catabolic process GO:0044257 155 0.036
intracellular mrna localization GO:0008298 4 0.036
associative learning GO:0008306 61 0.036
negative regulation of cellular component organization GO:0051129 194 0.036
purine nucleoside catabolic process GO:0006152 205 0.036
positive regulation of hydrolase activity GO:0051345 148 0.036
establishment of organelle localization GO:0051656 122 0.036
axonal fasciculation GO:0007413 15 0.035
positive regulation of neuron projection development GO:0010976 79 0.035
macromolecule methylation GO:0043414 120 0.035
positive regulation of cell death GO:0010942 224 0.035
protein transport into membrane raft GO:0032596 4 0.035
negative regulation of synapse assembly GO:0051964 3 0.035
negative regulation of reproductive process GO:2000242 31 0.035
adherens junction organization GO:0034332 28 0.035
developmental cell growth GO:0048588 84 0.034
positive regulation of cell motility GO:2000147 116 0.034
mitral valve development GO:0003174 4 0.034
megakaryocyte differentiation GO:0030219 26 0.034
digestive tract development GO:0048565 190 0.034
regulation of translation GO:0006417 71 0.034
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.034
Mouse
regulation of transporter activity GO:0032409 57 0.034
positive regulation of lymphocyte activation GO:0051251 140 0.034
positive regulation of synapse assembly GO:0051965 18 0.034
multicellular organismal homeostasis GO:0048871 164 0.034
multi organism behavior GO:0051705 62 0.034
regulation of exocytosis GO:0017157 61 0.034
multi organism reproductive behavior GO:0044705 29 0.034
negative regulation of fat cell differentiation GO:0045599 36 0.034
protein modification by small protein conjugation or removal GO:0070647 207 0.034
purine nucleoside triphosphate metabolic process GO:0009144 226 0.033
dephosphorylation GO:0016311 129 0.033
positive regulation of actin filament bundle assembly GO:0032233 11 0.033
hindbrain morphogenesis GO:0021575 46 0.033
response to extracellular stimulus GO:0009991 127 0.033
ventral trunk neural crest cell migration GO:0036486 4 0.033
regulation of cell substrate adhesion GO:0010810 73 0.033
homeostasis of number of cells GO:0048872 210 0.033
monosaccharide transport GO:0015749 58 0.033
establishment of planar polarity GO:0001736 28 0.033
hematopoietic progenitor cell differentiation GO:0002244 143 0.032
response to decreased oxygen levels GO:0036293 59 0.032
tube closure GO:0060606 91 0.032
negative regulation of axon extension GO:0030517 19 0.032
positive regulation of fatty acid oxidation GO:0046321 4 0.032
regulation of metal ion transport GO:0010959 106 0.032
adaptive immune response GO:0002250 155 0.032
regulation of endopeptidase activity GO:0052548 89 0.031
negative regulation of homeostatic process GO:0032845 71 0.031
branchiomotor neuron axon guidance GO:0021785 7 0.031
regulation of binding GO:0051098 111 0.031
regulation of cellular component size GO:0032535 121 0.031
alcohol metabolic process GO:0006066 116 0.031
heart process GO:0003015 94 0.031
establishment of protein localization to organelle GO:0072594 118 0.031
germinal center formation GO:0002467 16 0.031
myotube differentiation GO:0014902 105 0.031
Mouse
organonitrogen compound biosynthetic process GO:1901566 192 0.031
organelle disassembly GO:1903008 2 0.031
regulation of phospholipid biosynthetic process GO:0071071 3 0.031
positive regulation of protein kinase activity GO:0045860 144 0.030
regulation of apoptotic signaling pathway GO:2001233 197 0.030
establishment or maintenance of cell polarity GO:0007163 86 0.030
Worm
regulation of transforming growth factor beta2 production GO:0032909 2 0.030
odontogenesis of dentin containing tooth GO:0042475 66 0.030
regulation of lymphocyte proliferation GO:0050670 117 0.030
regulation of peptide transport GO:0090087 91 0.030
positive regulation of cell adhesion GO:0045785 80 0.030
regulation of dendritic spine development GO:0060998 22 0.030
circadian rhythm GO:0007623 114 0.030
Mouse
histone modification GO:0016570 159 0.030
regulation of hormone levels GO:0010817 211 0.030
cardiac cell fate specification GO:0060912 2 0.029
heart morphogenesis GO:0003007 178 0.029

Mark4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.145
disease of anatomical entity DOID:7 0 0.049
musculoskeletal system disease DOID:17 0 0.049
nervous system disease DOID:863 0 0.042
epilepsy syndrome DOID:1826 0 0.033
central nervous system disease DOID:331 0 0.033
brain disease DOID:936 0 0.033
electroclinical syndrome DOID:0050701 0 0.033
inherited metabolic disorder DOID:655 0 0.030