Mus musculus

0 known processes

Mark3

MAP/microtubule affinity-regulating kinase 3

(Aliases: MPK10,C-TAK1,A430080F22Rik,KIAA4230,Emk2,1600015G02Rik,ETK1,ETK-1)

Mark3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of organelle organization GO:0033043 289 0.138
regulation of cell cycle GO:0051726 281 0.124
Mouse
mrna metabolic process GO:0016071 84 0.101
mitotic cell cycle GO:0000278 195 0.097
Mouse
cell division GO:0051301 120 0.092
Worm
organelle fission GO:0048285 170 0.088
regulation of cellular ketone metabolic process GO:0010565 66 0.081
Mouse
cell adhesion GO:0007155 329 0.078
cellular response to dna damage stimulus GO:0006974 207 0.078
rna processing GO:0006396 105 0.074
ras protein signal transduction GO:0007265 77 0.074
cell growth GO:0016049 130 0.072
mitotic cell cycle process GO:1903047 159 0.065
actin cytoskeleton organization GO:0030036 220 0.063
muscle cell differentiation GO:0042692 261 0.061
Mouse
cellular protein catabolic process GO:0044257 155 0.061
negative regulation of molecular function GO:0044092 258 0.061
Mouse
negative regulation of protein metabolic process GO:0051248 282 0.060
nuclear transport GO:0051169 139 0.059
amine metabolic process GO:0009308 45 0.059
regulation of cell cycle process GO:0010564 160 0.057
regulation of mapk cascade GO:0043408 248 0.056
protein modification by small protein conjugation or removal GO:0070647 207 0.054
oocyte axis specification GO:0007309 2 0.052
spermatogenesis GO:0007283 284 0.051
cellular ketone metabolic process GO:0042180 84 0.050
Mouse
apoptotic signaling pathway GO:0097190 306 0.050
regulation of cellular response to stress GO:0080135 159 0.049
mapk cascade GO:0000165 281 0.049
cellular amino acid metabolic process GO:0006520 103 0.048
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.048
regulation of cellular amine metabolic process GO:0033238 20 0.048
heterocycle catabolic process GO:0046700 280 0.048
small gtpase mediated signal transduction GO:0007264 97 0.047
posttranscriptional regulation of gene expression GO:0010608 155 0.047
positive regulation of apoptotic process GO:0043065 217 0.046
nuclear division GO:0000280 158 0.045
regulation of cell growth GO:0001558 91 0.044
cellular nitrogen compound catabolic process GO:0044270 280 0.044
negative regulation of cellular component organization GO:0051129 194 0.043
nucleotide metabolic process GO:0009117 332 0.043
modification dependent protein catabolic process GO:0019941 133 0.042
meiotic cell cycle GO:0051321 122 0.041
nucleoside phosphate metabolic process GO:0006753 338 0.040
positive regulation of programmed cell death GO:0043068 218 0.040
regulation of cell division GO:0051302 76 0.039
positive regulation of cell death GO:0010942 224 0.039
protein localization to organelle GO:0033365 185 0.039
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.038
regulation of protein kinase activity GO:0045859 232 0.038
cation transport GO:0006812 399 0.036
dephosphorylation GO:0016311 129 0.036
mrna processing GO:0006397 63 0.036
regulation of cellular amino acid metabolic process GO:0006521 5 0.035
organelle assembly GO:0070925 177 0.035
nucleocytoplasmic transport GO:0006913 139 0.035
development of primary sexual characteristics GO:0045137 143 0.035
Worm
germ cell development GO:0007281 185 0.035
response to light stimulus GO:0009416 135 0.034
Mouse
nucleobase containing small molecule metabolic process GO:0055086 352 0.034
aromatic compound catabolic process GO:0019439 286 0.034
regulation of apoptotic signaling pathway GO:2001233 197 0.034
regulation of purine nucleotide metabolic process GO:1900542 169 0.034
cytoplasmic transport GO:0016482 234 0.034
endomembrane system organization GO:0010256 147 0.034
positive regulation of cellular amine metabolic process GO:0033240 5 0.033
protein localization to nucleus GO:0034504 121 0.033
nitrogen compound transport GO:0071705 271 0.033
male gamete generation GO:0048232 285 0.033
purine ribonucleoside catabolic process GO:0046130 205 0.033
protein autophosphorylation GO:0046777 61 0.033
microtubule based process GO:0007017 236 0.032
nucleoside phosphate catabolic process GO:1901292 222 0.032
protein modification by small protein conjugation GO:0032446 187 0.032
intracellular protein transport GO:0006886 204 0.032
negative regulation of cellular protein metabolic process GO:0032269 247 0.032
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.031
synapse organization GO:0050808 125 0.031
ribonucleoside triphosphate metabolic process GO:0009199 220 0.031
regulation of protein serine threonine kinase activity GO:0071900 157 0.030
meiotic nuclear division GO:0007126 115 0.030
macromolecule catabolic process GO:0009057 281 0.030
purine containing compound metabolic process GO:0072521 311 0.029
muscle cell development GO:0055001 133 0.029
mitotic nuclear division GO:0007067 48 0.029
regulation of cellular catabolic process GO:0031329 242 0.029
regulation of stress activated mapk cascade GO:0032872 69 0.029
purine nucleoside metabolic process GO:0042278 241 0.029
adult behavior GO:0030534 135 0.028
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.028
regulation of protein localization GO:0032880 231 0.028
Mouse
regulation of cell projection organization GO:0031344 206 0.028
establishment of protein localization to organelle GO:0072594 118 0.028
endocytosis GO:0006897 168 0.028
regulation of transferase activity GO:0051338 263 0.028
pole plasm assembly GO:0007315 2 0.028
regulation of neuron differentiation GO:0045664 281 0.027
positive regulation of mapk cascade GO:0043410 170 0.027
mrna splicing via spliceosome GO:0000398 43 0.027
jnk cascade GO:0007254 72 0.027
positive regulation of kinase activity GO:0033674 155 0.027
nucleoside catabolic process GO:0009164 206 0.027
nucleoside metabolic process GO:0009116 246 0.026
organonitrogen compound catabolic process GO:1901565 264 0.026
axonogenesis GO:0007409 274 0.026
purine ribonucleoside metabolic process GO:0046128 241 0.026
positive regulation of protein phosphorylation GO:0001934 242 0.026
protein import into nucleus GO:0006606 95 0.026
negative regulation of apoptotic signaling pathway GO:2001234 104 0.026
intracellular mrna localization GO:0008298 4 0.026
protein targeting GO:0006605 143 0.026
regulation of hydrolase activity GO:0051336 246 0.026
ribonucleotide catabolic process GO:0009261 208 0.025
cellular amine metabolic process GO:0044106 44 0.025
dna metabolic process GO:0006259 303 0.025
regulation of neuron projection development GO:0010975 169 0.025
negative regulation of phosphate metabolic process GO:0045936 184 0.025
ubiquitin dependent protein catabolic process GO:0006511 129 0.025
gonad development GO:0008406 141 0.025
Worm
cellular macromolecule catabolic process GO:0044265 206 0.025
cellular protein complex assembly GO:0043623 116 0.024
cell type specific apoptotic process GO:0097285 268 0.024
dna repair GO:0006281 107 0.024
regulation of proteolysis GO:0030162 164 0.024
positive regulation of protein modification process GO:0031401 299 0.024
regulation of jnk cascade GO:0046328 62 0.023
stress activated protein kinase signaling cascade GO:0031098 81 0.023
establishment of organelle localization GO:0051656 122 0.023
covalent chromatin modification GO:0016569 163 0.023
negative regulation of intracellular signal transduction GO:1902532 167 0.023
purine nucleoside triphosphate catabolic process GO:0009146 203 0.023
regulation of protein stability GO:0031647 52 0.023
regulation of protein maturation GO:1903317 96 0.022
regulation of ras protein signal transduction GO:0046578 114 0.022
forebrain development GO:0030900 302 0.022
negative regulation of cell proliferation GO:0008285 296 0.022
peptidyl amino acid modification GO:0018193 336 0.022
Worm
nucleoside triphosphate catabolic process GO:0009143 205 0.022
purine ribonucleotide metabolic process GO:0009150 290 0.022
carbohydrate metabolic process GO:0005975 230 0.022
Mouse
organic cyclic compound catabolic process GO:1901361 295 0.022
ribonucleoside metabolic process GO:0009119 245 0.022
purine nucleoside triphosphate metabolic process GO:0009144 226 0.022
membrane organization GO:0061024 245 0.022
regulation of cellular component biogenesis GO:0044087 181 0.022
negative regulation of protein modification process GO:0031400 163 0.022
response to radiation GO:0009314 165 0.022
Mouse
oocyte construction GO:0007308 2 0.022
regulation of mitotic cell cycle GO:0007346 126 0.022
Mouse
nucleoside triphosphate metabolic process GO:0009141 230 0.021
purine nucleoside catabolic process GO:0006152 205 0.021
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.021
regulation of kinase activity GO:0043549 249 0.021
regulation of nuclear division GO:0051783 56 0.021
ribonucleoside triphosphate catabolic process GO:0009203 199 0.021
locomotory behavior GO:0007626 195 0.021
positive regulation of cell development GO:0010720 237 0.021
regulation of cellular component size GO:0032535 121 0.021
regulation of defense response GO:0031347 233 0.021
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.021
Mouse
chromatin organization GO:0006325 206 0.021
gland development GO:0048732 330 0.021
regionalization GO:0003002 337 0.021
stress activated mapk cascade GO:0051403 80 0.021
regulation of response to wounding GO:1903034 189 0.021
positive regulation of protein kinase activity GO:0045860 144 0.020
regulation of intracellular transport GO:0032386 159 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.020
positive regulation of organelle organization GO:0010638 128 0.020
transmembrane transport GO:0055085 412 0.020
mitotic cytokinesis GO:0000281 4 0.020
carbohydrate derivative biosynthetic process GO:1901137 183 0.020
meiotic cell cycle process GO:1903046 77 0.020
organelle localization GO:0051640 179 0.020
regulation of anatomical structure size GO:0090066 178 0.020
regulation of ion transport GO:0043269 215 0.020
chromatin modification GO:0016568 187 0.020
rna splicing GO:0008380 54 0.019
regulation of establishment of protein localization GO:0070201 181 0.019
potassium ion transport GO:0006813 52 0.019
myosin filament organization GO:0031033 3 0.019
protein maturation GO:0051604 176 0.019
ribonucleotide metabolic process GO:0009259 291 0.019
mitochondrion organization GO:0007005 134 0.019
regulation of mitotic cell cycle phase transition GO:1901990 73 0.019
response to extracellular stimulus GO:0009991 127 0.019
regulation of system process GO:0044057 200 0.019
oocyte anterior posterior axis specification GO:0007314 2 0.019
negative regulation of cell cycle GO:0045786 123 0.019
regulation of hormone levels GO:0010817 211 0.019
proteasomal protein catabolic process GO:0010498 98 0.019
maintenance of location GO:0051235 89 0.019
regulation of mrna processing GO:0050684 41 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.018
asymmetric neuroblast division GO:0055059 1 0.018
Worm
cognition GO:0050890 149 0.018
muscle tissue development GO:0060537 308 0.018
Mouse
myeloid cell differentiation GO:0030099 233 0.018
organophosphate catabolic process GO:0046434 232 0.018
regulation of protein transport GO:0051223 163 0.018
purine nucleotide metabolic process GO:0006163 302 0.018
epithelial tube formation GO:0072175 130 0.017
synaptic transmission GO:0007268 329 0.017
nuclear import GO:0051170 95 0.017
nucleotide catabolic process GO:0009166 217 0.017
protein catabolic process GO:0030163 221 0.017
cellular chemical homeostasis GO:0055082 215 0.017
macroautophagy GO:0016236 21 0.017
positive regulation of nervous system development GO:0051962 221 0.017
divalent inorganic cation transport GO:0072511 178 0.017
neuron migration GO:0001764 122 0.017
myosin filament assembly GO:0031034 2 0.017
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.017
cellular carbohydrate metabolic process GO:0044262 119 0.017
Mouse
extrinsic apoptotic signaling pathway GO:0097191 126 0.017
myeloid leukocyte differentiation GO:0002573 119 0.017
glycosyl compound metabolic process GO:1901657 246 0.016
leukocyte differentiation GO:0002521 342 0.016
rna interference GO:0016246 2 0.016
protein processing GO:0016485 163 0.016
inflammatory response GO:0006954 244 0.016
positive regulation of cellular catabolic process GO:0031331 148 0.016
regulation of chromatin organization GO:1902275 57 0.016
ribose phosphate metabolic process GO:0019693 291 0.016
regulation of binding GO:0051098 111 0.016
microtubule cytoskeleton organization GO:0000226 157 0.016
peptidyl tyrosine phosphorylation GO:0018108 143 0.016
lipid localization GO:0010876 126 0.016
spermatid development GO:0007286 108 0.016
regulation of protein complex assembly GO:0043254 83 0.016
positive regulation of nucleotide catabolic process GO:0030813 88 0.016
negative regulation of organelle organization GO:0010639 90 0.016
rhythmic process GO:0048511 174 0.016
Mouse
stem cell differentiation GO:0048863 268 0.015
regulation of cell migration GO:0030334 219 0.015
response to lipopolysaccharide GO:0032496 128 0.015
telencephalon development GO:0021537 186 0.015
regulation of ion transmembrane transport GO:0034765 119 0.015
response to oxidative stress GO:0006979 123 0.015
single organism nuclear import GO:1902593 95 0.015
regulation of purine nucleotide catabolic process GO:0033121 122 0.015
protein localization to membrane GO:0072657 108 0.015
positive regulation of stress activated mapk cascade GO:0032874 48 0.015
protein depolymerization GO:0051261 34 0.015
phagocytosis GO:0006909 66 0.015
blastocyst development GO:0001824 80 0.015
negative regulation of cellular amine metabolic process GO:0033239 1 0.015
cellular response to peptide hormone stimulus GO:0071375 92 0.015
Mouse
microtubule polymerization or depolymerization GO:0031109 26 0.015
dendrite development GO:0016358 115 0.015
immune effector process GO:0002252 321 0.015
regulation of erk1 and erk2 cascade GO:0070372 71 0.015
regulation of homeostatic process GO:0032844 182 0.015
epithelial cell development GO:0002064 159 0.014
embryonic epithelial tube formation GO:0001838 130 0.014
learning or memory GO:0007611 148 0.014
regulation of map kinase activity GO:0043405 120 0.014
inclusion body assembly GO:0070841 3 0.014
t cell activation GO:0042110 289 0.014
negative regulation of cell cycle phase transition GO:1901988 48 0.014
regulation of cytoskeleton organization GO:0051493 122 0.014
regulation of nucleotide metabolic process GO:0006140 169 0.014
negative regulation of response to dna damage stimulus GO:2001021 10 0.014
regulation of cytokine production GO:0001817 266 0.014
positive regulation of neuron differentiation GO:0045666 141 0.014
gtp metabolic process GO:0046039 144 0.014
protein import GO:0017038 101 0.014
response to organic cyclic compound GO:0014070 198 0.014
pallium development GO:0021543 120 0.014
regulation of vesicle mediated transport GO:0060627 139 0.014
neuron apoptotic process GO:0051402 142 0.014
response to insulin GO:0032868 100 0.014
Mouse
regulation of wnt signaling pathway GO:0030111 123 0.014
negative regulation of mitotic cell cycle GO:0045930 58 0.014
cation transmembrane transport GO:0098655 266 0.014
cell substrate adhesion GO:0031589 130 0.014
cellular response to hormone stimulus GO:0032870 150 0.014
Mouse
amide transport GO:0042886 138 0.014
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.014
transmission of nerve impulse GO:0019226 76 0.014
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.013
Mouse
calcium ion homeostasis GO:0055074 127 0.013
epithelial cell proliferation GO:0050673 174 0.013
response to temperature stimulus GO:0009266 55 0.013
regulation of metal ion transport GO:0010959 106 0.013
regulation of histone modification GO:0031056 56 0.013
regulation of membrane potential GO:0042391 192 0.013
regulation of secretion GO:0051046 274 0.013
guanosine containing compound metabolic process GO:1901068 144 0.013
peptidyl serine modification GO:0018209 83 0.013
Worm
metal ion homeostasis GO:0055065 189 0.013
intrinsic apoptotic signaling pathway GO:0097193 132 0.013
cellular response to external stimulus GO:0071496 88 0.013
neuronal action potential GO:0019228 54 0.013
positive regulation of growth GO:0045927 104 0.013
regulation of multi organism process GO:0043900 111 0.013
regulation of cell adhesion GO:0030155 154 0.013
regulation of exit from mitosis GO:0007096 1 0.013
muscle system process GO:0003012 141 0.013
learning GO:0007612 98 0.013
regulation of inflammatory response GO:0050727 147 0.013
regulation of mrna metabolic process GO:1903311 43 0.013
lipid transport GO:0006869 98 0.013
response to organonitrogen compound GO:0010243 246 0.013
Mouse
cerebral cortex development GO:0021987 86 0.013
positive regulation of hydrolase activity GO:0051345 148 0.013
regulation of cell activation GO:0050865 289 0.013
nucleoside monophosphate metabolic process GO:0009123 85 0.013
stem cell development GO:0048864 219 0.012
intermediate filament based process GO:0045103 27 0.012
purine nucleotide catabolic process GO:0006195 211 0.012
inorganic cation transmembrane transport GO:0098662 207 0.012
zygotic determination of anterior posterior axis embryo GO:0007354 3 0.012
negative regulation of proteolysis GO:0045861 74 0.012
receptor mediated endocytosis GO:0006898 51 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.012
compound eye development GO:0048749 1 0.012
retrograde transport endosome to golgi GO:0042147 2 0.012
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 22 0.012
neural precursor cell proliferation GO:0061351 121 0.012
Worm
negative regulation of phosphorus metabolic process GO:0010563 184 0.012
regulation of actin filament based process GO:0032970 99 0.012
peptidyl tyrosine modification GO:0018212 145 0.012
rna splicing via transesterification reactions GO:0000375 43 0.012
spermatid differentiation GO:0048515 115 0.012
peptide transport GO:0015833 133 0.012
ribonucleoside monophosphate catabolic process GO:0009158 57 0.012
urogenital system development GO:0001655 261 0.012
stem cell proliferation GO:0072089 117 0.012
Worm
positive regulation of cell projection organization GO:0031346 95 0.012
divalent metal ion transport GO:0070838 172 0.012
cytokine production GO:0001816 319 0.012
positive regulation of cell adhesion GO:0045785 80 0.012
skeletal muscle organ development GO:0060538 163 0.012
i kappab kinase nf kappab signaling GO:0007249 85 0.012
regulation of nucleocytoplasmic transport GO:0046822 73 0.012
rho protein signal transduction GO:0007266 32 0.012
multicellular organism growth GO:0035264 161 0.012
Mouse
negative regulation of binding GO:0051100 39 0.012
glycosyl compound catabolic process GO:1901658 206 0.012
exocytosis GO:0006887 121 0.012
purine ribonucleotide catabolic process GO:0009154 208 0.012
positive regulation of transferase activity GO:0051347 167 0.012
response to peptide GO:1901652 136 0.011
Mouse
cellular response to nutrient levels GO:0031669 64 0.011
regulation of chromatin modification GO:1903308 57 0.011
positive regulation of nucleotide metabolic process GO:0045981 114 0.011
male meiosis GO:0007140 37 0.011
regulation of cytoplasmic transport GO:1903649 112 0.011
cellular homeostasis GO:0019725 240 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.011
erk1 and erk2 cascade GO:0070371 77 0.011
cellular response to extracellular stimulus GO:0031668 81 0.011
regulation of cell cycle phase transition GO:1901987 77 0.011
developmental growth involved in morphogenesis GO:0060560 138 0.011
ribonucleoprotein complex subunit organization GO:0071826 28 0.011
regulation of mitosis GO:0007088 29 0.011
maternal determination of anterior posterior axis embryo GO:0008358 2 0.011
small molecule biosynthetic process GO:0044283 132 0.011
epithelial tube morphogenesis GO:0060562 303 0.011
actin filament based movement GO:0030048 23 0.011
oxidation reduction process GO:0055114 342 0.011
renal system development GO:0072001 225 0.011
negative regulation of protein maturation GO:1903318 79 0.011
actomyosin structure organization GO:0031032 56 0.011
regulation of microtubule based process GO:0032886 52 0.011
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.011
protein acylation GO:0043543 64 0.011
positive regulation of dna templated transcription elongation GO:0032786 2 0.011
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.011
morphogenesis of embryonic epithelium GO:0016331 159 0.011
multi multicellular organism process GO:0044706 109 0.011
nucleoside monophosphate catabolic process GO:0009125 59 0.011
positive regulation of jnk cascade GO:0046330 46 0.011
skin development GO:0043588 220 0.011
regulation of epithelial cell proliferation GO:0050678 141 0.011
regulation of cellular protein catabolic process GO:1903362 61 0.011
regulation of neuron death GO:1901214 134 0.011
neuron death GO:0070997 154 0.011
negative regulation of cell cycle process GO:0010948 69 0.011
regulation of actin cytoskeleton organization GO:0032956 84 0.011
adult locomotory behavior GO:0008344 91 0.011
regulation of endocytosis GO:0030100 69 0.011
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.011
methylation GO:0032259 134 0.011
regulation of cell motility GO:2000145 236 0.011
cytokinetic process GO:0032506 2 0.011
regulation of neuron apoptotic process GO:0043523 122 0.011
fertilization GO:0009566 127 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.011
microtubule nucleation GO:0007020 2 0.011
multicellular organismal signaling GO:0035637 91 0.011
homeostasis of number of cells GO:0048872 210 0.011
cellular response to lipid GO:0071396 145 0.011
synapse assembly GO:0007416 56 0.011
sequestering of calcium ion GO:0051208 18 0.011
organic hydroxy compound metabolic process GO:1901615 203 0.011
inorganic ion transmembrane transport GO:0098660 234 0.011
positive regulation of protein transport GO:0051222 93 0.010
organonitrogen compound biosynthetic process GO:1901566 192 0.010
epidermis development GO:0008544 187 0.010
single fertilization GO:0007338 82 0.010
positive regulation of cellular component biogenesis GO:0044089 94 0.010
regulation of protein processing GO:0070613 96 0.010
response to nutrient levels GO:0031667 109 0.010
cell junction organization GO:0034330 77 0.010
wnt signaling pathway GO:0016055 188 0.010
negative regulation of cell development GO:0010721 169 0.010
regulation of nucleoside metabolic process GO:0009118 130 0.010
cell cycle checkpoint GO:0000075 47 0.010
wound healing GO:0042060 157 0.010
actin filament organization GO:0007015 113 0.010
cellular divalent inorganic cation homeostasis GO:0072503 127 0.010
response to inorganic substance GO:0010035 96 0.010
cellular response to molecule of bacterial origin GO:0071219 83 0.010
cellular response to oxidative stress GO:0034599 76 0.010
positive regulation of apoptotic signaling pathway GO:2001235 95 0.010

Mark3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.019
musculoskeletal system disease DOID:17 0 0.019
nervous system disease DOID:863 0 0.014
disease of cellular proliferation DOID:14566 0 0.010