Mus musculus

0 known processes

Extl3

exostoses (multiple)-like 3

(Aliases: mKIAA0519,2900009G18Rik,KIAA0519,AU040105,Ext1l)

Extl3 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular ketone metabolic process GO:0010565 66 0.359
regulation of cellular amine metabolic process GO:0033238 20 0.224
amine metabolic process GO:0009308 45 0.215
regulation of cellular amino acid metabolic process GO:0006521 5 0.205
positive regulation of protein phosphorylation GO:0001934 242 0.203
peptidyl amino acid modification GO:0018193 336 0.191
cellular amine metabolic process GO:0044106 44 0.187
nucleoside phosphate metabolic process GO:0006753 338 0.183
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.178
cellular ketone metabolic process GO:0042180 84 0.165
regulation of cell size GO:0008361 72 0.157
Zebrafish
cellular amino acid metabolic process GO:0006520 103 0.153
positive regulation of cellular amine metabolic process GO:0033240 5 0.152
chemotaxis GO:0006935 247 0.149
Zebrafish Mouse
positive regulation of nervous system development GO:0051962 221 0.146
forebrain development GO:0030900 302 0.145
Mouse
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.142
regulation of cell projection organization GO:0031344 206 0.137
Zebrafish
regulation of neuron differentiation GO:0045664 281 0.131
Zebrafish
purine ribonucleotide metabolic process GO:0009150 290 0.129
cellular response to growth factor stimulus GO:0071363 197 0.120
Zebrafish
skeletal system development GO:0001501 356 0.114
Mouse
telencephalon development GO:0021537 186 0.113
Mouse
organonitrogen compound catabolic process GO:1901565 264 0.109
ribonucleotide metabolic process GO:0009259 291 0.109
nucleobase containing small molecule metabolic process GO:0055086 352 0.105
neuron projection guidance GO:0097485 141 0.103
Zebrafish Mouse
cartilage development GO:0051216 140 0.101
regulation of cell motility GO:2000145 236 0.101
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.100
Zebrafish
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.098
carbohydrate derivative biosynthetic process GO:1901137 183 0.094
Zebrafish Mouse Worm Fly
membrane organization GO:0061024 245 0.092
negative regulation of synapse assembly GO:0051964 3 0.091
purine containing compound metabolic process GO:0072521 311 0.087
neuronal action potential GO:0019228 54 0.086
regulation of cell growth GO:0001558 91 0.085
Zebrafish
organophosphate catabolic process GO:0046434 232 0.085
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.085
Zebrafish
ribose phosphate metabolic process GO:0019693 291 0.085
rho protein signal transduction GO:0007266 32 0.084
small gtpase mediated signal transduction GO:0007264 97 0.084
action potential GO:0001508 78 0.081
regulation of transferase activity GO:0051338 263 0.080
anatomical structure homeostasis GO:0060249 145 0.080
regulation of neuron projection development GO:0010975 169 0.079
Zebrafish
regulation of nucleotide metabolic process GO:0006140 169 0.079
nucleotide metabolic process GO:0009117 332 0.079
gland development GO:0048732 330 0.079
positive regulation of cell projection organization GO:0031346 95 0.077
positive regulation of cell development GO:0010720 237 0.077
negative regulation of growth GO:0045926 99 0.077
ribonucleoside metabolic process GO:0009119 245 0.076
regulation of hydrolase activity GO:0051336 246 0.075
regulation of apoptotic signaling pathway GO:2001233 197 0.073
glycoprotein biosynthetic process GO:0009101 89 0.073
Zebrafish Mouse Worm Fly
regulation of anatomical structure size GO:0090066 178 0.071
Zebrafish
peptidyl tyrosine phosphorylation GO:0018108 143 0.071
connective tissue development GO:0061448 179 0.071
purine containing compound catabolic process GO:0072523 213 0.071
regulation of cellular component size GO:0032535 121 0.071
Zebrafish
carbohydrate derivative catabolic process GO:1901136 231 0.070
positive regulation of protein modification process GO:0031401 299 0.070
transmission of nerve impulse GO:0019226 76 0.070
nucleoside catabolic process GO:0009164 206 0.070
camera type eye development GO:0043010 266 0.069
regulation of axon extension GO:0030516 43 0.069
Zebrafish
regulation of cell migration GO:0030334 219 0.069
positive regulation of cellular catabolic process GO:0031331 148 0.068
epithelial cell proliferation GO:0050673 174 0.068
ras protein signal transduction GO:0007265 77 0.068
blood vessel morphogenesis GO:0048514 285 0.067
carbohydrate metabolic process GO:0005975 230 0.067
Fly
positive regulation of organelle organization GO:0010638 128 0.067
regulation of extent of cell growth GO:0061387 52 0.066
Zebrafish
regulation of purine nucleotide metabolic process GO:1900542 169 0.066
negative regulation of nervous system development GO:0051961 156 0.065
regulation of organelle organization GO:0033043 289 0.065
epithelial tube morphogenesis GO:0060562 303 0.065
regulation of protein kinase activity GO:0045859 232 0.063
positive regulation of apoptotic process GO:0043065 217 0.063
purine ribonucleoside catabolic process GO:0046130 205 0.062
sensory organ morphogenesis GO:0090596 242 0.061
negative regulation of cellular component organization GO:0051129 194 0.061
cell growth GO:0016049 130 0.060
Zebrafish
ribonucleotide catabolic process GO:0009261 208 0.059
synapse organization GO:0050808 125 0.059
retina morphogenesis in camera type eye GO:0060042 45 0.058
regionalization GO:0003002 337 0.058
germ cell development GO:0007281 185 0.058
heterocycle catabolic process GO:0046700 280 0.057
defecation GO:0030421 1 0.057
glycosyl compound catabolic process GO:1901658 206 0.057
glycoprotein metabolic process GO:0009100 116 0.056
Zebrafish Mouse Worm Fly
regulation of gtp catabolic process GO:0033124 113 0.056
purine ribonucleoside metabolic process GO:0046128 241 0.056
nucleoside triphosphate catabolic process GO:0009143 205 0.055
synapse assembly GO:0007416 56 0.054
nucleotide catabolic process GO:0009166 217 0.054
cellular nitrogen compound catabolic process GO:0044270 280 0.054
protein localization to organelle GO:0033365 185 0.054
regulation of cellular component biogenesis GO:0044087 181 0.054
positive regulation of gtpase activity GO:0043547 85 0.053
regulation of mapk cascade GO:0043408 248 0.053
nucleoside triphosphate metabolic process GO:0009141 230 0.053
microtubule based process GO:0007017 236 0.052
engulfment of apoptotic cell GO:0043652 3 0.052
central nervous system neuron differentiation GO:0021953 162 0.052
aromatic compound catabolic process GO:0019439 286 0.052
ensheathment of neurons GO:0007272 76 0.052
ribonucleoside triphosphate catabolic process GO:0009203 199 0.051
regulation of membrane potential GO:0042391 192 0.050
angiogenesis GO:0001525 201 0.050
myelination in peripheral nervous system GO:0022011 19 0.050
ubiquitin dependent protein catabolic process GO:0006511 129 0.050
wnt signaling pathway GO:0016055 188 0.050
Fly
developmental growth involved in morphogenesis GO:0060560 138 0.049
Zebrafish
synaptic transmission GO:0007268 329 0.049
ion transmembrane transport GO:0034220 361 0.049
positive regulation of neuron differentiation GO:0045666 141 0.048
spermatogenesis GO:0007283 284 0.048
regulation of purine nucleotide catabolic process GO:0033121 122 0.048
mapk cascade GO:0000165 281 0.048
regulation of cell cycle GO:0051726 281 0.047
gliogenesis GO:0042063 141 0.047
morphogenesis of a branching structure GO:0001763 203 0.047
purine nucleoside metabolic process GO:0042278 241 0.047
skeletal system morphogenesis GO:0048705 203 0.047
cell type specific apoptotic process GO:0097285 268 0.047
axonogenesis GO:0007409 274 0.047
Zebrafish Mouse
skin development GO:0043588 220 0.046
response to growth factor GO:0070848 198 0.046
Zebrafish
homeostasis of number of cells GO:0048872 210 0.046
cytoplasmic transport GO:0016482 234 0.046
stem cell development GO:0048864 219 0.045
branching morphogenesis of an epithelial tube GO:0048754 159 0.045
axon ensheathment GO:0008366 76 0.045
photoreceptor cell differentiation GO:0046530 52 0.044
ribonucleoside catabolic process GO:0042454 206 0.044
positive regulation of neuron projection development GO:0010976 79 0.044
regulation of ras gtpase activity GO:0032318 88 0.044
protein localization to nucleus GO:0034504 121 0.043
purine nucleotide metabolic process GO:0006163 302 0.043
cerebral cortex development GO:0021987 86 0.043
single organismal cell cell adhesion GO:0016337 131 0.043
guanosine containing compound catabolic process GO:1901069 144 0.043
ossification GO:0001503 216 0.042
endomembrane system organization GO:0010256 147 0.042
regulation of cell cycle process GO:0010564 160 0.042
positive regulation of cell motility GO:2000147 116 0.042
protein import into nucleus GO:0006606 95 0.042
nucleoside phosphate catabolic process GO:1901292 222 0.041
single organism cell adhesion GO:0098602 156 0.041
negative regulation of protein metabolic process GO:0051248 282 0.041
limb morphogenesis GO:0035108 149 0.041
regulation of protein localization GO:0032880 231 0.041
mucopolysaccharide metabolic process GO:1903510 25 0.041
Fly
organic cyclic compound catabolic process GO:1901361 295 0.041
peptidyl tyrosine modification GO:0018212 145 0.040
regulation of kinase activity GO:0043549 249 0.040
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.040
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.040
Fly
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.039
ribonucleoside triphosphate metabolic process GO:0009199 220 0.039
guanosine containing compound metabolic process GO:1901068 144 0.039
sensory perception of umami taste GO:0050917 4 0.039
regulation of cellular catabolic process GO:0031329 242 0.039
multicellular organismal signaling GO:0035637 91 0.038
regulation of neuron death GO:1901214 134 0.038
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.038
aminoglycan metabolic process GO:0006022 34 0.038
Zebrafish Fly
glycosyl compound metabolic process GO:1901657 246 0.038
single organism nuclear import GO:1902593 95 0.038
multicellular organism growth GO:0035264 161 0.037
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.037
peptidyl serine modification GO:0018209 83 0.037
morphogenesis of embryonic epithelium GO:0016331 159 0.037
digestive system development GO:0055123 200 0.037
Mouse Worm
purine nucleoside triphosphate catabolic process GO:0009146 203 0.037
negative regulation of molecular function GO:0044092 258 0.037
positive regulation of binding GO:0051099 49 0.037
cation transport GO:0006812 399 0.037
bone development GO:0060348 120 0.037
cerebellar granule cell precursor tangential migration GO:0021935 1 0.037
developmental maturation GO:0021700 193 0.037
myeloid cell differentiation GO:0030099 233 0.036
purine ribonucleotide catabolic process GO:0009154 208 0.036
respiratory system development GO:0060541 190 0.036
ameboidal type cell migration GO:0001667 128 0.036
actin filament organization GO:0007015 113 0.036
regulation of cellular protein catabolic process GO:1903362 61 0.036
regulation of cell adhesion GO:0030155 154 0.036
cellular homeostasis GO:0019725 240 0.036
purine nucleoside catabolic process GO:0006152 205 0.036
protein import GO:0017038 101 0.035
multicellular organismal homeostasis GO:0048871 164 0.035
myeloid cell homeostasis GO:0002262 114 0.035
leukocyte differentiation GO:0002521 342 0.035
positive regulation of gtp catabolic process GO:0033126 85 0.035
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.035
modification dependent protein catabolic process GO:0019941 133 0.035
regulation of homeostatic process GO:0032844 182 0.035
g protein coupled receptor signaling pathway GO:0007186 243 0.035
regulation of cytoskeleton organization GO:0051493 122 0.034
cellular lipid metabolic process GO:0044255 323 0.034
respiratory tube development GO:0030323 167 0.034
blood circulation GO:0008015 195 0.033
negative regulation of phosphate metabolic process GO:0045936 184 0.033
rhythmic process GO:0048511 174 0.033
microtubule cytoskeleton organization GO:0000226 157 0.033
organelle fission GO:0048285 170 0.033
heart morphogenesis GO:0003007 178 0.033
intracellular protein transport GO:0006886 204 0.033
male gamete generation GO:0048232 285 0.033
glycosylation GO:0070085 62 0.033
adult behavior GO:0030534 135 0.033
hematopoietic progenitor cell differentiation GO:0002244 143 0.033
tissue homeostasis GO:0001894 115 0.033
cell division GO:0051301 120 0.033
axon guidance GO:0007411 141 0.033
Zebrafish Mouse
immune effector process GO:0002252 321 0.032
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.032
nucleocytoplasmic transport GO:0006913 139 0.032
circulatory system process GO:0003013 197 0.032
appendage development GO:0048736 166 0.032
Zebrafish
peptidyl threonine modification GO:0018210 31 0.032
positive regulation of protein kinase activity GO:0045860 144 0.031
pallium development GO:0021543 120 0.031
regulation of cellular response to stress GO:0080135 159 0.031
extrinsic apoptotic signaling pathway GO:0097191 126 0.031
regulation of intracellular transport GO:0032386 159 0.031
negative regulation of cellular amine metabolic process GO:0033239 1 0.030
purine nucleotide catabolic process GO:0006195 211 0.030
positive regulation of growth GO:0045927 104 0.030
positive regulation of programmed cell death GO:0043068 218 0.030
maintenance of location GO:0051235 89 0.030
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.030
fatty acid transmembrane transport GO:1902001 1 0.030
developmental cell growth GO:0048588 84 0.030
Zebrafish
positive regulation of nucleotide metabolic process GO:0045981 114 0.030
chondrocyte differentiation GO:0002062 72 0.030
regulation of reproductive process GO:2000241 66 0.030
positive regulation of ras gtpase activity GO:0032320 65 0.030
neural tube closure GO:0001843 90 0.030
negative regulation of protein phosphorylation GO:0001933 126 0.029
myelination GO:0042552 74 0.029
erythrocyte differentiation GO:0030218 88 0.029
dendrite development GO:0016358 115 0.029
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.029
positive regulation of hydrolase activity GO:0051345 148 0.029
neuron projection extension GO:1990138 64 0.029
Zebrafish
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.029
tube formation GO:0035148 140 0.029
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.028
dna metabolic process GO:0006259 303 0.028
regulation of ossification GO:0030278 112 0.028
regulation of transmembrane transport GO:0034762 128 0.028
glial cell differentiation GO:0010001 131 0.028
tissue migration GO:0090130 68 0.028
endothelial cell migration GO:0043542 44 0.028
gtp catabolic process GO:0006184 143 0.028
neural precursor cell proliferation GO:0061351 121 0.028
protein localization to plasma membrane GO:0072659 57 0.028
protein autophosphorylation GO:0046777 61 0.028
positive regulation of nucleoside metabolic process GO:0045979 91 0.028
mitotic cell cycle process GO:1903047 159 0.028
negative regulation of cell development GO:0010721 169 0.027
regulation of ras protein signal transduction GO:0046578 114 0.027
digestive tract morphogenesis GO:0048546 147 0.027
Mouse
establishment of vesicle localization GO:0051650 81 0.027
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.027
positive regulation of apoptotic signaling pathway GO:2001235 95 0.027
regulation of system process GO:0044057 200 0.027
cellular macromolecule catabolic process GO:0044265 206 0.027
regulation of body fluid levels GO:0050878 162 0.027
positive regulation of cell growth GO:0030307 33 0.027
posttranscriptional regulation of gene expression GO:0010608 155 0.027
protein processing GO:0016485 163 0.027
cellular response to abiotic stimulus GO:0071214 56 0.026
gtp metabolic process GO:0046039 144 0.026
nucleoside metabolic process GO:0009116 246 0.026
embryonic organ morphogenesis GO:0048562 276 0.026
cellular response to dna damage stimulus GO:0006974 207 0.026
regulation of rho gtpase activity GO:0032319 58 0.026
positive regulation of axon extension GO:0045773 20 0.026
cellular protein complex assembly GO:0043623 116 0.026
adult locomotory behavior GO:0008344 91 0.026
regulation of nucleoside metabolic process GO:0009118 130 0.026
positive regulation of cell migration GO:0030335 109 0.026
regulation of rho protein signal transduction GO:0035023 71 0.025
embryonic limb morphogenesis GO:0030326 126 0.025
nuclear transport GO:0051169 139 0.025
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.025
rhodopsin mediated signaling pathway GO:0016056 4 0.025
regulation of epithelial cell proliferation GO:0050678 141 0.025
purine nucleoside triphosphate metabolic process GO:0009144 226 0.025
protein polymerization GO:0051258 57 0.025
positive regulation of cell death GO:0010942 224 0.025
positive regulation of transferase activity GO:0051347 167 0.025
smoothened signaling pathway GO:0007224 105 0.025
Fly
cytokine production GO:0001816 319 0.025
epithelial cell migration GO:0010631 63 0.025
microtubule based transport GO:0010970 50 0.024
macromolecule catabolic process GO:0009057 281 0.024
apoptotic signaling pathway GO:0097190 306 0.024
protein kinase b signaling GO:0043491 74 0.024
regulation of nucleotide catabolic process GO:0030811 122 0.024
regulation of actin cytoskeleton organization GO:0032956 84 0.024
urogenital system development GO:0001655 261 0.024
reactive oxygen species biosynthetic process GO:1903409 8 0.024
cation homeostasis GO:0055080 212 0.024
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.024
cation transmembrane transport GO:0098655 266 0.024
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 26 0.024
sulfur compound metabolic process GO:0006790 100 0.024
Zebrafish Mouse Worm Fly
retina development in camera type eye GO:0060041 119 0.023
proteasomal protein catabolic process GO:0010498 98 0.023
dephosphorylation GO:0016311 129 0.023
regulation of cell activation GO:0050865 289 0.023
photoreceptor cell development GO:0042461 40 0.023
sequestering of calcium ion GO:0051208 18 0.023
cellular response to epidermal growth factor stimulus GO:0071364 4 0.023
regulation of angiogenesis GO:0045765 81 0.023
positive regulation of rho gtpase activity GO:0032321 41 0.023
t cell differentiation GO:0030217 174 0.023
morphogenesis of a branching epithelium GO:0061138 193 0.023
peptidyl threonine phosphorylation GO:0018107 31 0.023
kidney development GO:0001822 213 0.023
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.022
oxidation reduction process GO:0055114 342 0.022
postganglionic parasympathetic nervous system development GO:0021784 2 0.022
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.022
anion transport GO:0006820 177 0.022
regulation of neuron apoptotic process GO:0043523 122 0.022
lens development in camera type eye GO:0002088 62 0.022
nitrogen compound transport GO:0071705 271 0.022
spermatid differentiation GO:0048515 115 0.022
vesicle localization GO:0051648 86 0.022
compound eye development GO:0048749 1 0.022
regulation of map kinase activity GO:0043405 120 0.022
cell maturation GO:0048469 127 0.022
glycerophospholipid metabolic process GO:0006650 71 0.022
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.022
multi multicellular organism process GO:0044706 109 0.022
primary neural tube formation GO:0014020 95 0.022
response to organonitrogen compound GO:0010243 246 0.022
sulfur compound biosynthetic process GO:0044272 37 0.021
Zebrafish Mouse Worm Fly
muscle cell development GO:0055001 133 0.021
establishment of protein localization to organelle GO:0072594 118 0.021
female gamete generation GO:0007292 74 0.021
positive regulation of protein kinase b signaling GO:0051897 32 0.021
regulation of wnt signaling pathway GO:0030111 123 0.021
olfactory lobe development GO:0021988 32 0.021
Mouse
negative regulation of neuron differentiation GO:0045665 101 0.021
neuron death GO:0070997 154 0.021
negative regulation of blood vessel endothelial cell migration GO:0043537 3 0.021
positive regulation of kinase activity GO:0033674 155 0.021
gastrulation GO:0007369 116 0.021
Mouse
establishment of organelle localization GO:0051656 122 0.021
mitotic cell cycle GO:0000278 195 0.021
negative regulation of cell projection organization GO:0031345 56 0.021
regulation of cellular response to growth factor stimulus GO:0090287 82 0.021
Zebrafish
lipid homeostasis GO:0055088 63 0.021
transmembrane transport GO:0055085 412 0.021
central nervous system neuron development GO:0021954 67 0.021
negative regulation of cell migration GO:0030336 59 0.021
negative regulation of cell motility GO:2000146 61 0.020
neuron apoptotic process GO:0051402 142 0.020
leukocyte migration GO:0050900 124 0.020
regulation of organ morphogenesis GO:2000027 144 0.020
nephron epithelium morphogenesis GO:0072088 68 0.020
learning or memory GO:0007611 148 0.020
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.020
regulation of gliogenesis GO:0014013 50 0.020
multi organism behavior GO:0051705 62 0.020
regulation of ion transport GO:0043269 215 0.020
eye photoreceptor cell development GO:0042462 31 0.020
anion transmembrane transport GO:0098656 71 0.020
actin filament polymerization GO:0030041 44 0.020
protein glycosylation GO:0006486 55 0.020
negative regulation of phosphorus metabolic process GO:0010563 184 0.020
negative regulation of protein modification process GO:0031400 163 0.020
telencephalon cell migration GO:0022029 55 0.020
lung development GO:0030324 164 0.020
white fat cell proliferation GO:0070343 2 0.020
reactive oxygen species metabolic process GO:0072593 84 0.020
positive regulation of mapk cascade GO:0043410 170 0.019
t cell activation GO:0042110 289 0.019
blastocyst development GO:0001824 80 0.019
lymphocyte differentiation GO:0030098 242 0.019
peptide transport GO:0015833 133 0.019
negative regulation of phosphorylation GO:0042326 166 0.019
protein maturation GO:0051604 176 0.019
cerebral cortex cell migration GO:0021795 44 0.019
regulation of vasculature development GO:1901342 88 0.019
regulation of proteolysis GO:0030162 164 0.019
cell activation involved in immune response GO:0002263 126 0.019
epithelium migration GO:0090132 63 0.019
limbic system development GO:0021761 72 0.019
regulation of multi organism process GO:0043900 111 0.019
neural tube formation GO:0001841 108 0.019
regulation of reactive oxygen species metabolic process GO:2000377 40 0.019
phosphatidylinositol mediated signaling GO:0048015 41 0.019
cellular chemical homeostasis GO:0055082 215 0.019
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.019
regulation of lymphocyte mediated immunity GO:0002706 84 0.019
regulation of secretion GO:0051046 274 0.019
forebrain generation of neurons GO:0021872 63 0.019
lymphocyte homeostasis GO:0002260 64 0.019
organelle localization GO:0051640 179 0.019
spermatid development GO:0007286 108 0.019
reproductive behavior GO:0019098 32 0.019
negative regulation of cellular protein metabolic process GO:0032269 247 0.019
organic anion transport GO:0015711 137 0.019
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.019
leukocyte mediated immunity GO:0002443 174 0.019
cellular carbohydrate metabolic process GO:0044262 119 0.018
Fly
peptidyl serine phosphorylation GO:0018105 74 0.018
response to organic cyclic compound GO:0014070 198 0.018
cellular protein catabolic process GO:0044257 155 0.018
response to osmotic stress GO:0006970 21 0.018
protein targeting GO:0006605 143 0.018
eye photoreceptor cell differentiation GO:0001754 41 0.018
organophosphate biosynthetic process GO:0090407 122 0.018
fertilization GO:0009566 127 0.018
vegf activated neuropilin signaling pathway GO:0038190 2 0.018
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.018
response to radiation GO:0009314 165 0.018
positive regulation of intracellular protein transport GO:0090316 42 0.018
production of molecular mediator of immune response GO:0002440 103 0.018
neuron migration GO:0001764 122 0.018
stem cell differentiation GO:0048863 268 0.018
chromatin modification GO:0016568 187 0.018
tube closure GO:0060606 91 0.018
positive regulation of cell cycle process GO:0090068 61 0.018
meiotic cell cycle process GO:1903046 77 0.018
regulation of erk1 and erk2 cascade GO:0070372 71 0.018
proteoglycan metabolic process GO:0006029 38 0.018
Zebrafish Mouse Worm Fly
reactive nitrogen species metabolic process GO:2001057 0 0.018
organ growth GO:0035265 117 0.018
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.018
regulation of defense response GO:0031347 233 0.018
exocytosis GO:0006887 121 0.018
nuclear division GO:0000280 158 0.017
heart contraction GO:0060047 93 0.017
cell chemotaxis GO:0060326 81 0.017
cell recognition GO:0008037 83 0.017
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.017
negative regulation of cell cycle GO:0045786 123 0.017
actin cytoskeleton organization GO:0030036 220 0.017
negative regulation of hydrolase activity GO:0051346 71 0.017
mesonephros development GO:0001823 97 0.017
regulation of ral gtpase activity GO:0032315 4 0.017
regulation of leukocyte differentiation GO:1902105 159 0.017
multi organism reproductive behavior GO:0044705 29 0.017
negative regulation of apoptotic signaling pathway GO:2001234 104 0.017
positive regulation of rac gtpase activity GO:0032855 14 0.017
alcohol metabolic process GO:0006066 116 0.017
bone morphogenesis GO:0060349 78 0.017
carbohydrate homeostasis GO:0033500 128 0.017
neural retina development GO:0003407 41 0.017
oocyte axis specification GO:0007309 2 0.017
positive regulation of cytoskeleton organization GO:0051495 49 0.017
regulation of endothelial cell migration GO:0010594 22 0.017
striated muscle tissue development GO:0014706 293 0.017
negative regulation of organelle organization GO:0010639 90 0.017
fat cell differentiation GO:0045444 160 0.017
regulation of protein binding GO:0043393 60 0.017
steroid metabolic process GO:0008202 119 0.017
lipid biosynthetic process GO:0008610 179 0.017
positive regulation of immune effector process GO:0002699 107 0.017
nucleotide biosynthetic process GO:0009165 78 0.017
mesoderm development GO:0007498 100 0.017
Mouse
regulation of ion transmembrane transport GO:0034765 119 0.017
development of primary sexual characteristics GO:0045137 143 0.016
nuclear import GO:0051170 95 0.016
microtubule based movement GO:0007018 84 0.016
central nervous system neuron axonogenesis GO:0021955 28 0.016
epithelial tube formation GO:0072175 130 0.016
lung alveolus development GO:0048286 45 0.016
muscle tissue development GO:0060537 308 0.016
embryonic epithelial tube formation GO:0001838 130 0.016
positive regulation of chemotaxis GO:0050921 38 0.016
organic hydroxy compound metabolic process GO:1901615 203 0.016
plasma membrane organization GO:0007009 90 0.016
mesenchymal cell development GO:0014031 93 0.016
muscle fiber development GO:0048747 76 0.016
forebrain cell migration GO:0021885 58 0.016
cognition GO:0050890 149 0.016

Extl3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
nervous system disease DOID:863 0 0.028
central nervous system disease DOID:331 0 0.022
disease of cellular proliferation DOID:14566 0 0.022
disease of metabolism DOID:0014667 0 0.020
musculoskeletal system disease DOID:17 0 0.018
cancer DOID:162 0 0.017