Mus musculus

0 known processes

Calhm2

calcium homeostasis modulator 2

(Aliases: Fam26b,2810048G17Rik)

Calhm2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of protein metabolic process GO:0051248 282 0.088
cellular amino acid metabolic process GO:0006520 103 0.088
g protein coupled receptor signaling pathway GO:0007186 243 0.084
cytokine production GO:0001816 319 0.070
purine nucleotide metabolic process GO:0006163 302 0.069
negative regulation of cell proliferation GO:0008285 296 0.065
regulation of cellular ketone metabolic process GO:0010565 66 0.059
peptidyl amino acid modification GO:0018193 336 0.058
regulation of cellular amino acid metabolic process GO:0006521 5 0.056
fat cell differentiation GO:0045444 160 0.052
negative regulation of immune system process GO:0002683 209 0.052
nucleotide metabolic process GO:0009117 332 0.052
positive regulation of cell death GO:0010942 224 0.052
regulation of cellular amine metabolic process GO:0033238 20 0.050
purine ribonucleoside metabolic process GO:0046128 241 0.049
carbohydrate metabolic process GO:0005975 230 0.049
negative regulation of protein modification process GO:0031400 163 0.048
regulation of cell cycle GO:0051726 281 0.048
cell adhesion GO:0007155 329 0.047
homeostasis of number of cells GO:0048872 210 0.046
ribose phosphate metabolic process GO:0019693 291 0.045
positive regulation of programmed cell death GO:0043068 218 0.044
activation of immune response GO:0002253 138 0.044
small gtpase mediated signal transduction GO:0007264 97 0.044
negative regulation of cellular amine metabolic process GO:0033239 1 0.043
positive regulation of apoptotic process GO:0043065 217 0.043
positive regulation of cellular catabolic process GO:0031331 148 0.042
negative regulation of cellular protein metabolic process GO:0032269 247 0.042
cellular ketone metabolic process GO:0042180 84 0.042
lymphocyte differentiation GO:0030098 242 0.041
amine metabolic process GO:0009308 45 0.041
negative regulation of protein phosphorylation GO:0001933 126 0.041
regulation of defense response GO:0031347 233 0.040
male gamete generation GO:0048232 285 0.040
oxidation reduction process GO:0055114 342 0.039
leukocyte differentiation GO:0002521 342 0.039
skeletal system development GO:0001501 356 0.039
regulation of nucleotide metabolic process GO:0006140 169 0.038
regulation of cytokine production GO:0001817 266 0.038
microtubule based process GO:0007017 236 0.038
carbohydrate derivative biosynthetic process GO:1901137 183 0.038
cellular amine metabolic process GO:0044106 44 0.038
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.037
apoptotic signaling pathway GO:0097190 306 0.037
extracellular structure organization GO:0043062 148 0.037
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.037
multicellular organism growth GO:0035264 161 0.036
carbohydrate derivative catabolic process GO:1901136 231 0.036
nucleobase containing small molecule metabolic process GO:0055086 352 0.035
purine containing compound metabolic process GO:0072521 311 0.035
nucleoside phosphate metabolic process GO:0006753 338 0.035
glycosyl compound catabolic process GO:1901658 206 0.035
ribonucleoside triphosphate metabolic process GO:0009199 220 0.035
cytokine mediated signaling pathway GO:0019221 115 0.035
regulation of hydrolase activity GO:0051336 246 0.034
multicellular organismal homeostasis GO:0048871 164 0.034
cellular response to cytokine stimulus GO:0071345 189 0.034
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.034
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.034
nucleoside phosphate catabolic process GO:1901292 222 0.033
organonitrogen compound biosynthetic process GO:1901566 192 0.033
blood circulation GO:0008015 195 0.033
positive regulation of apoptotic signaling pathway GO:2001235 95 0.033
regulation of innate immune response GO:0045088 91 0.033
myeloid cell differentiation GO:0030099 233 0.033
ribonucleotide metabolic process GO:0009259 291 0.033
purine ribonucleotide metabolic process GO:0009150 290 0.032
rhythmic process GO:0048511 174 0.032
ribonucleoside metabolic process GO:0009119 245 0.032
immune effector process GO:0002252 321 0.031
hematopoietic progenitor cell differentiation GO:0002244 143 0.031
negative regulation of lymphocyte activation GO:0051250 91 0.031
positive regulation of nervous system development GO:0051962 221 0.030
regulation of purine nucleotide metabolic process GO:1900542 169 0.030
heterocycle catabolic process GO:0046700 280 0.030
stem cell differentiation GO:0048863 268 0.030
regulation of transferase activity GO:0051338 263 0.030
nucleoside catabolic process GO:0009164 206 0.030
positive regulation of hydrolase activity GO:0051345 148 0.030
protein processing GO:0016485 163 0.029
monocarboxylic acid metabolic process GO:0032787 191 0.029
innate immune response GO:0045087 157 0.029
lymphocyte mediated immunity GO:0002449 139 0.029
ras protein signal transduction GO:0007265 77 0.029
purine nucleotide catabolic process GO:0006195 211 0.028
leukocyte mediated immunity GO:0002443 174 0.028
positive regulation of gtp catabolic process GO:0033126 85 0.028
regulation of purine nucleotide catabolic process GO:0033121 122 0.028
regulation of cell activation GO:0050865 289 0.027
glycoprotein metabolic process GO:0009100 116 0.027
extracellular matrix organization GO:0030198 147 0.027
tissue homeostasis GO:0001894 115 0.027
regulation of cellular component biogenesis GO:0044087 181 0.027
nucleoside triphosphate metabolic process GO:0009141 230 0.027
purine ribonucleotide catabolic process GO:0009154 208 0.027
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.026
chromatin modification GO:0016568 187 0.026
t cell activation GO:0042110 289 0.026
macromolecule glycosylation GO:0043413 55 0.026
chromatin organization GO:0006325 206 0.026
negative regulation of molecular function GO:0044092 258 0.026
purine nucleoside metabolic process GO:0042278 241 0.025
muscle tissue development GO:0060537 308 0.025
mitotic cell cycle GO:0000278 195 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.025
myeloid leukocyte differentiation GO:0002573 119 0.025
protein modification by small protein conjugation GO:0032446 187 0.025
anatomical structure homeostasis GO:0060249 145 0.024
positive regulation of protein modification process GO:0031401 299 0.024
circulatory system process GO:0003013 197 0.024
regionalization GO:0003002 337 0.024
carbohydrate homeostasis GO:0033500 128 0.024
spermatogenesis GO:0007283 284 0.024
organ growth GO:0035265 117 0.024
forebrain development GO:0030900 302 0.024
aromatic compound catabolic process GO:0019439 286 0.024
histone modification GO:0016570 159 0.023
chondrocyte differentiation GO:0002062 72 0.023
muscle system process GO:0003012 141 0.023
aortic valve morphogenesis GO:0003180 4 0.023
glycosylation GO:0070085 62 0.023
negative regulation of cellular component organization GO:0051129 194 0.023
organic cyclic compound catabolic process GO:1901361 295 0.023
positive regulation of nucleotide metabolic process GO:0045981 114 0.023
negative regulation of phosphorylation GO:0042326 166 0.023
regulation of apoptotic signaling pathway GO:2001233 197 0.023
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.023
defense response to other organism GO:0098542 197 0.023
intracellular distribution of mitochondria GO:0048312 1 0.022
kidney development GO:0001822 213 0.022
negative regulation of phosphorus metabolic process GO:0010563 184 0.022
positive regulation of gtpase activity GO:0043547 85 0.022
negative regulation of cell cycle GO:0045786 123 0.022
regulation of leukocyte differentiation GO:1902105 159 0.022
defense response to bacterium GO:0042742 119 0.022
regulation of cellular response to stress GO:0080135 159 0.022
regulation of nucleoside metabolic process GO:0009118 130 0.021
rho protein signal transduction GO:0007266 32 0.021
response to organonitrogen compound GO:0010243 246 0.021
nucleotide catabolic process GO:0009166 217 0.021
glycosyl compound metabolic process GO:1901657 246 0.021
nucleoside metabolic process GO:0009116 246 0.021
mapk cascade GO:0000165 281 0.021
purine nucleoside triphosphate metabolic process GO:0009144 226 0.021
glucose homeostasis GO:0042593 128 0.021
regulation of system process GO:0044057 200 0.021
protein ubiquitination GO:0016567 171 0.021
protein modification by small protein conjugation or removal GO:0070647 207 0.021
regulation of t cell activation GO:0050863 170 0.020
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.020
divalent metal ion transport GO:0070838 172 0.020
negative regulation of intracellular signal transduction GO:1902532 167 0.020
regulation of neuron differentiation GO:0045664 281 0.020
ossification GO:0001503 216 0.020
gland development GO:0048732 330 0.020
wnt signaling pathway GO:0016055 188 0.019
regulation of lymphocyte activation GO:0051249 240 0.019
cation transmembrane transport GO:0098655 266 0.019
regulation of kinase activity GO:0043549 249 0.019
cellular nitrogen compound catabolic process GO:0044270 280 0.019
regulation of cell motility GO:2000145 236 0.019
organonitrogen compound catabolic process GO:1901565 264 0.019
organelle localization GO:0051640 179 0.019
macromolecule catabolic process GO:0009057 281 0.019
nucleoside triphosphate catabolic process GO:0009143 205 0.019
cell substrate adhesion GO:0031589 130 0.019
regulation of gtp catabolic process GO:0033124 113 0.019
regulation of mapk cascade GO:0043408 248 0.019
placenta development GO:0001890 140 0.018
negative regulation of cytokine production GO:0001818 84 0.018
purine containing compound catabolic process GO:0072523 213 0.018
lateral inhibition GO:0046331 1 0.018
myeloid cell homeostasis GO:0002262 114 0.018
endomembrane system organization GO:0010256 147 0.018
negative regulation of cell development GO:0010721 169 0.018
positive regulation of protein phosphorylation GO:0001934 242 0.018
protein catabolic process GO:0030163 221 0.018
cell fate commitment GO:0045165 210 0.018
mitochondrion distribution GO:0048311 4 0.018
transmembrane transport GO:0055085 412 0.018
intestinal epithelial structure maintenance GO:0060729 4 0.018
ribonucleoside catabolic process GO:0042454 206 0.018
negative regulation of cell activation GO:0050866 111 0.017
b cell activation GO:0042113 161 0.017
regulation of secretion GO:0051046 274 0.017
protein maturation GO:0051604 176 0.017
cellular lipid metabolic process GO:0044255 323 0.017
neural precursor cell proliferation GO:0061351 121 0.017
respiratory system development GO:0060541 190 0.017
dna metabolic process GO:0006259 303 0.017
ovulation cycle GO:0042698 59 0.017
regulation of vesicle mediated transport GO:0060627 139 0.017
regulation of mast cell differentiation GO:0060375 3 0.017
positive regulation of cytokine production GO:0001819 174 0.017
positive regulation of transferase activity GO:0051347 167 0.017
cell division GO:0051301 120 0.017
ribonucleotide catabolic process GO:0009261 208 0.017
purine ribonucleoside catabolic process GO:0046130 205 0.017
cartilage development GO:0051216 140 0.017
regulation of organelle organization GO:0033043 289 0.016
regulation of myeloid cell differentiation GO:0045637 96 0.016
glycoprotein biosynthetic process GO:0009101 89 0.016
cell differentiation in spinal cord GO:0021515 53 0.016
regulation of neuron projection development GO:0010975 169 0.016
regulation of cell projection organization GO:0031344 206 0.016
monosaccharide metabolic process GO:0005996 106 0.016
cellular response to hormone stimulus GO:0032870 150 0.016
endocytosis GO:0006897 168 0.016
intrinsic apoptotic signaling pathway GO:0097193 132 0.016
positive regulation of neuron differentiation GO:0045666 141 0.016
purine nucleoside catabolic process GO:0006152 205 0.016
positive regulation of defense response GO:0031349 124 0.016
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.016
mitotic cell cycle process GO:1903047 159 0.016
protein hydroxylation GO:0018126 4 0.016
protein glycosylation GO:0006486 55 0.016
response to molecule of bacterial origin GO:0002237 143 0.016
nuclear division GO:0000280 158 0.016
synapse organization GO:0050808 125 0.016
regulation of binding GO:0051098 111 0.016
muscle cell differentiation GO:0042692 261 0.016
regulation of interleukin 6 production GO:0032675 55 0.016
erythrocyte differentiation GO:0030218 88 0.016
purine nucleoside triphosphate catabolic process GO:0009146 203 0.016
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.016
defecation GO:0030421 1 0.015
adaptive immune response GO:0002250 155 0.015
stem cell maintenance GO:0019827 130 0.015
response to lipopolysaccharide GO:0032496 128 0.015
positive regulation of lymphocyte activation GO:0051251 140 0.015
ribonucleoside triphosphate catabolic process GO:0009203 199 0.015
skeletal system morphogenesis GO:0048705 203 0.015
cation transport GO:0006812 399 0.015
cell growth GO:0016049 130 0.015
positive regulation of cellular amine metabolic process GO:0033240 5 0.015
regulation of nucleotide catabolic process GO:0030811 122 0.015
gtp metabolic process GO:0046039 144 0.015
positive regulation of cell development GO:0010720 237 0.015
divalent inorganic cation transport GO:0072511 178 0.015
negative regulation of nervous system development GO:0051961 156 0.015
epidermis development GO:0008544 187 0.015
organophosphate catabolic process GO:0046434 232 0.015
response to oxidative stress GO:0006979 123 0.015
peptidyl lysine modification GO:0018205 77 0.015
positive regulation of nucleoside metabolic process GO:0045979 91 0.015
response to acid chemical GO:0001101 111 0.015
renal system development GO:0072001 225 0.015
respiratory tube development GO:0030323 167 0.015
regulation of cell cycle process GO:0010564 160 0.015
circadian rhythm GO:0007623 114 0.014
regulation of proteolysis GO:0030162 164 0.014
cellular homeostasis GO:0019725 240 0.014
regulation of ossification GO:0030278 112 0.014
epithelial cell proliferation GO:0050673 174 0.014
stem cell proliferation GO:0072089 117 0.014
regulation of lymphocyte differentiation GO:0045619 107 0.014
mitochondrion organization GO:0007005 134 0.014
stem cell development GO:0048864 219 0.014
immune response activating signal transduction GO:0002757 116 0.014
guanosine containing compound catabolic process GO:1901069 144 0.014
embryonic epithelial tube formation GO:0001838 130 0.014
leukocyte proliferation GO:0070661 172 0.014
actin cytoskeleton organization GO:0030036 220 0.014
negative regulation of defense response GO:0031348 77 0.014
antigen receptor mediated signaling pathway GO:0050851 64 0.014
regulation of ras protein signal transduction GO:0046578 114 0.014
t cell differentiation GO:0030217 174 0.014
calcium ion transport GO:0006816 159 0.014
somite development GO:0061053 81 0.013
regulation of fat cell differentiation GO:0045598 81 0.013
ear development GO:0043583 200 0.013
cellular response to acid chemical GO:0071229 68 0.013
response to organic cyclic compound GO:0014070 198 0.013
regulation of homeostatic process GO:0032844 182 0.013
regulation of osteoblast differentiation GO:0045667 67 0.013
odontogenesis of dentin containing tooth GO:0042475 66 0.013
peptidyl proline hydroxylation GO:0019511 3 0.013
leukocyte activation involved in immune response GO:0002366 126 0.013
positive regulation of proteolysis GO:0045862 85 0.013
immune response regulating signaling pathway GO:0002764 125 0.013
blood vessel morphogenesis GO:0048514 285 0.013
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.013
lung development GO:0030324 164 0.013
transdifferentiation GO:0060290 1 0.013
connective tissue development GO:0061448 179 0.013
positive regulation of protein kinase activity GO:0045860 144 0.013
tissue remodeling GO:0048771 102 0.013
organic hydroxy compound metabolic process GO:1901615 203 0.013
cell maturation GO:0048469 127 0.013
microtubule cytoskeleton organization GO:0000226 157 0.013
cell type specific apoptotic process GO:0097285 268 0.013
neural tube development GO:0021915 160 0.013
positive regulation of innate immune response GO:0045089 80 0.013
inflammatory response GO:0006954 244 0.013
response to oxygen levels GO:0070482 62 0.013
negative regulation of phosphate metabolic process GO:0045936 184 0.013
cellular response to dna damage stimulus GO:0006974 207 0.012
organophosphate biosynthetic process GO:0090407 122 0.012
compound eye development GO:0048749 1 0.012
regulation of anatomical structure size GO:0090066 178 0.012
organelle fission GO:0048285 170 0.012
regulation of organ morphogenesis GO:2000027 144 0.012
regulation of map kinase activity GO:0043405 120 0.012
alpha beta t cell activation GO:0046631 91 0.012
nitrogen compound transport GO:0071705 271 0.012
cardiac right ventricle formation GO:0003219 3 0.012
mitral valve morphogenesis GO:0003183 4 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.012
glial cell differentiation GO:0010001 131 0.012
camera type eye development GO:0043010 266 0.012
fertilization GO:0009566 127 0.012
lymphocyte proliferation GO:0046651 164 0.012
epithelial tube morphogenesis GO:0060562 303 0.012
muscle contraction GO:0006936 101 0.012
regulation of cell adhesion GO:0030155 154 0.012
regulation of protein catabolic process GO:0042176 108 0.012
hormone secretion GO:0046879 128 0.012
reactive oxygen species metabolic process GO:0072593 84 0.012
morphogenesis of embryonic epithelium GO:0016331 159 0.012
striated muscle tissue development GO:0014706 293 0.012
regulation of membrane potential GO:0042391 192 0.012
intracellular receptor signaling pathway GO:0030522 74 0.012
gtp catabolic process GO:0006184 143 0.012
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.012
guanosine containing compound metabolic process GO:1901068 144 0.012
determination of left right symmetry GO:0007368 80 0.012
mesoderm formation GO:0001707 62 0.012
regulation of tube size GO:0035150 57 0.012
cd4 positive alpha beta t cell activation GO:0035710 45 0.012
cellular response to lipid GO:0071396 145 0.012
male gonad development GO:0008584 88 0.012
activation of innate immune response GO:0002218 56 0.012
covalent chromatin modification GO:0016569 163 0.012
regulation of interleukin 8 production GO:0032677 3 0.012
gliogenesis GO:0042063 141 0.012
methylation GO:0032259 134 0.012
response to radiation GO:0009314 165 0.012
regulation of circadian rhythm GO:0042752 58 0.012
regulation of blood pressure GO:0008217 93 0.012
midgut development GO:0007494 4 0.011
skin development GO:0043588 220 0.011
development of primary female sexual characteristics GO:0046545 73 0.011
regulation of cellular catabolic process GO:0031329 242 0.011
purinergic nucleotide receptor signaling pathway GO:0035590 3 0.011
skeletal muscle cell differentiation GO:0035914 66 0.011
response to inorganic substance GO:0010035 96 0.011
muscle cell development GO:0055001 133 0.011
negative regulation of growth GO:0045926 99 0.011
cellular response to inorganic substance GO:0071241 37 0.011
protein kinase b signaling GO:0043491 74 0.011
negative regulation of type b pancreatic cell apoptotic process GO:2000675 3 0.011
protein acylation GO:0043543 64 0.011
retrograde transport endosome to golgi GO:0042147 2 0.011
extrinsic apoptotic signaling pathway GO:0097191 126 0.011
cardiac ventricle development GO:0003231 83 0.011
digestive tract development GO:0048565 190 0.011
inorganic ion transmembrane transport GO:0098660 234 0.011
positive regulation of semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:2000764 1 0.011
mesenchyme development GO:0060485 152 0.011
embryonic placenta development GO:0001892 98 0.011
transmission of nerve impulse GO:0019226 76 0.011
regulation of epithelial cell proliferation GO:0050678 141 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
phosphatidylinositol 3 kinase signaling GO:0014065 36 0.011
cell activation involved in immune response GO:0002263 126 0.011
interleukin 8 production GO:0032637 4 0.011
posttranscriptional regulation of gene expression GO:0010608 155 0.011
alpha beta t cell differentiation GO:0046632 69 0.011
regulation of rho protein signal transduction GO:0035023 71 0.011
interleukin 6 production GO:0032635 58 0.011
palate development GO:0060021 76 0.011
regulation of protein localization GO:0032880 231 0.011
ion transmembrane transport GO:0034220 361 0.011
positive regulation of nucleotide catabolic process GO:0030813 88 0.011
skeletal muscle organ development GO:0060538 163 0.011
maintenance of location GO:0051235 89 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.010
cellular response to growth factor stimulus GO:0071363 197 0.010
regulation of transmembrane transport GO:0034762 128 0.010
central nervous system neuron differentiation GO:0021953 162 0.010
regulation of mitotic cell cycle GO:0007346 126 0.010
regulation of t cell differentiation GO:0045580 83 0.010
regulation of wnt signaling pathway GO:0030111 123 0.010
male sex differentiation GO:0046661 109 0.010
defense response to virus GO:0051607 68 0.010
neuroblast proliferation GO:0007405 49 0.010
b cell differentiation GO:0030183 78 0.010
positive regulation of organelle organization GO:0010638 128 0.010
regulation of protein serine threonine kinase activity GO:0071900 157 0.010
regulation of cellular component size GO:0032535 121 0.010
regulation of cell substrate adhesion GO:0010810 73 0.010
response to insulin GO:0032868 100 0.010
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.010
tube formation GO:0035148 140 0.010
response to growth factor GO:0070848 198 0.010
nucleoside phosphate biosynthetic process GO:1901293 79 0.010

Calhm2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.023
nervous system disease DOID:863 0 0.023
central nervous system disease DOID:331 0 0.012
musculoskeletal system disease DOID:17 0 0.011
immune system disease DOID:2914 0 0.011