Mus musculus

120 known processes

Cacna1c

calcium channel, voltage-dependent, L type, alpha 1C subunit

(Aliases: Cav1.2,Cchl1a1)

Cacna1c biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transmembrane transport GO:0055085 412 0.910
regulation of membrane potential GO:0042391 192 0.839
Mouse
regulation of ion transmembrane transport GO:0034765 119 0.826
cation transmembrane transport GO:0098655 266 0.793
ion transmembrane transport GO:0034220 361 0.732
calcium ion transmembrane transport GO:0070588 85 0.696
divalent metal ion transport GO:0070838 172 0.688
inorganic ion transmembrane transport GO:0098660 234 0.667
inorganic cation transmembrane transport GO:0098662 207 0.657
blood circulation GO:0008015 195 0.638
muscle system process GO:0003012 141 0.636
regulation of metal ion transport GO:0010959 106 0.633
Mouse
regulation of system process GO:0044057 200 0.583
circulatory system process GO:0003013 197 0.572
chemotaxis GO:0006935 247 0.539
regulation of heart contraction GO:0008016 77 0.538
Zebrafish Mouse
divalent inorganic cation transport GO:0072511 178 0.526
regulation of blood circulation GO:1903522 93 0.486
single organismal cell cell adhesion GO:0016337 131 0.450
angiogenesis GO:0001525 201 0.444
regulation of calcium ion transport GO:0051924 69 0.438
Mouse
second messenger mediated signaling GO:0019932 73 0.414
cation transport GO:0006812 399 0.406
locomotory behavior GO:0007626 195 0.385
purine containing compound metabolic process GO:0072521 311 0.374
heart morphogenesis GO:0003007 178 0.367
Zebrafish
actin filament based movement GO:0030048 23 0.366
axonogenesis GO:0007409 274 0.365
Mouse
transmission of nerve impulse GO:0019226 76 0.354
Mouse
calcium ion transport GO:0006816 159 0.353
regulation of cell motility GO:2000145 236 0.346
muscle contraction GO:0006936 101 0.342
cation homeostasis GO:0055080 212 0.337
regulation of muscle system process GO:0090257 80 0.327
synaptic transmission GO:0007268 329 0.325
potassium ion transmembrane transport GO:0071805 43 0.321
Mouse
ventricular cardiac muscle cell action potential GO:0086005 4 0.320
axon guidance GO:0007411 141 0.319
cardiac muscle cell contraction GO:0086003 7 0.311
regulation of cation channel activity GO:2001257 22 0.296
cellular ketone metabolic process GO:0042180 84 0.288
divalent inorganic cation homeostasis GO:0072507 138 0.283
blood vessel morphogenesis GO:0048514 285 0.283
cellular homeostasis GO:0019725 240 0.273
calcium mediated signaling using intracellular calcium source GO:0035584 3 0.272
regulation of striated muscle contraction GO:0006942 25 0.262
cellular calcium ion homeostasis GO:0006874 119 0.262
cellular amino acid metabolic process GO:0006520 103 0.257
Mouse
bone development GO:0060348 120 0.255
cell adhesion GO:0007155 329 0.252
regulation of ion transport GO:0043269 215 0.250
sa node cell action potential GO:0086015 4 0.245
Mouse
potassium ion homeostasis GO:0055075 4 0.223
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.221
calcium mediated signaling GO:0019722 46 0.220
striated muscle cell development GO:0055002 125 0.219
Mouse
metal ion homeostasis GO:0055065 189 0.217
stem cell development GO:0048864 219 0.215
muscle cell development GO:0055001 133 0.212
Mouse
muscle tissue development GO:0060537 308 0.208
Mouse
striated muscle tissue development GO:0014706 293 0.205
Mouse
developmental maturation GO:0021700 193 0.205
Mouse
regulation of hormone levels GO:0010817 211 0.202
camera type eye development GO:0043010 266 0.201
Mouse
negative regulation of cell development GO:0010721 169 0.201
ossification GO:0001503 216 0.198
single organism cell adhesion GO:0098602 156 0.198
cardiocyte differentiation GO:0035051 87 0.197
sensory perception GO:0007600 245 0.190
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.189
embryonic organ morphogenesis GO:0048562 276 0.188
Zebrafish
lung development GO:0030324 164 0.188
response to radiation GO:0009314 165 0.184
epithelial tube morphogenesis GO:0060562 303 0.184
muscle cell differentiation GO:0042692 261 0.181
Mouse
cellular chemical homeostasis GO:0055082 215 0.178
adult behavior GO:0030534 135 0.178
cardiac conduction GO:0061337 17 0.173
Mouse
adult locomotory behavior GO:0008344 91 0.171
leukocyte migration GO:0050900 124 0.170
positive regulation of ion transport GO:0043270 65 0.170
purine nucleoside metabolic process GO:0042278 241 0.168
anatomical structure homeostasis GO:0060249 145 0.166
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014808 12 0.166
tissue homeostasis GO:0001894 115 0.163
skeletal system development GO:0001501 356 0.163
Zebrafish Mouse
sympathetic neuron projection extension GO:0097490 4 0.161
establishment or maintenance of cell polarity GO:0007163 86 0.159
regulation of cellular catabolic process GO:0031329 242 0.156
cell type specific apoptotic process GO:0097285 268 0.148
Mouse
cardiac chamber development GO:0003205 108 0.146
amino acid transport GO:0006865 61 0.146
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.146
multicellular organismal homeostasis GO:0048871 164 0.144
fat cell differentiation GO:0045444 160 0.143
cell chemotaxis GO:0060326 81 0.141
urogenital system development GO:0001655 261 0.140
striated muscle contraction GO:0006941 45 0.137
Mouse
respiratory system development GO:0060541 190 0.134
activation of mapk activity involved in innate immune response GO:0035419 2 0.131
nitrogen compound transport GO:0071705 271 0.131
sympathetic neuron projection guidance GO:0097491 4 0.130
positive regulation of calcium ion transport GO:0051928 27 0.130
regulation of transmembrane transport GO:0034762 128 0.125
mitotic cell cycle GO:0000278 195 0.124
retina development in camera type eye GO:0060041 119 0.123
Mouse
protein catabolic process GO:0030163 221 0.123
amide transport GO:0042886 138 0.123
ribose phosphate metabolic process GO:0019693 291 0.122
rhythmic process GO:0048511 174 0.121
response to light stimulus GO:0009416 135 0.120
multicellular organismal signaling GO:0035637 91 0.120
Mouse
neuronal action potential GO:0019228 54 0.119
gonadotrophin releasing hormone neuronal migration to the hypothalamus GO:0021828 3 0.117
axonal fasciculation GO:0007413 15 0.116
apoptotic signaling pathway GO:0097190 306 0.115
positive regulation of ion transmembrane transport GO:0034767 24 0.114
ventral trunk neural crest cell migration GO:0036486 4 0.112
muscle fiber development GO:0048747 76 0.111
Mouse
ribonucleotide metabolic process GO:0009259 291 0.110
neuron projection guidance GO:0097485 141 0.110
regulation of ion transmembrane transporter activity GO:0032412 54 0.108
Mouse
detection of stimulus GO:0051606 84 0.108
organic anion transport GO:0015711 137 0.108
Mouse
response to organonitrogen compound GO:0010243 246 0.107
g protein coupled receptor signaling pathway GO:0007186 243 0.106
Mouse
actin mediated cell contraction GO:0070252 15 0.105
regulation of neuron projection development GO:0010975 169 0.104
Mouse
neuron migration GO:0001764 122 0.103
regulation of cell adhesion GO:0030155 154 0.102
positive regulation of protein modification process GO:0031401 299 0.102
stem cell differentiation GO:0048863 268 0.101
sensory organ morphogenesis GO:0090596 242 0.101
mesenchyme development GO:0060485 152 0.100
carboxylic acid transport GO:0046942 100 0.099
Mouse
anion transport GO:0006820 177 0.099
Mouse
nucleoside catabolic process GO:0009164 206 0.098
potassium ion transport GO:0006813 52 0.098
Mouse
regulation of cardiac muscle contraction by calcium ion signaling GO:0010882 9 0.097
nucleobase containing small molecule metabolic process GO:0055086 352 0.095
negative regulation of nervous system development GO:0051961 156 0.095
regulation of actin filament based process GO:0032970 99 0.094
glycosyl compound metabolic process GO:1901657 246 0.093
purine nucleotide metabolic process GO:0006163 302 0.093
myeloid cell homeostasis GO:0002262 114 0.093
compound eye development GO:0048749 1 0.089
axon ensheathment GO:0008366 76 0.089
organic cyclic compound catabolic process GO:1901361 295 0.089
asymmetric neuroblast division GO:0055059 1 0.088
heart contraction GO:0060047 93 0.088
Zebrafish Mouse
visual perception GO:0007601 52 0.088
Mouse
trunk neural crest cell migration GO:0036484 4 0.086
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.085
calcium ion homeostasis GO:0055074 127 0.082
peptidyl tyrosine phosphorylation GO:0018108 143 0.082
establishment of spindle localization GO:0051293 19 0.081
regulation of cell migration GO:0030334 219 0.081
peptidyl amino acid modification GO:0018193 336 0.081
cytosolic calcium ion homeostasis GO:0051480 70 0.081
Mouse
cellular response to cytokine stimulus GO:0071345 189 0.081
immune response activating signal transduction GO:0002757 116 0.080
maintenance of location GO:0051235 89 0.080
regulation of ion homeostasis GO:2000021 64 0.079
nucleotide metabolic process GO:0009117 332 0.079
regionalization GO:0003002 337 0.078
regulation of anatomical structure size GO:0090066 178 0.077
renal system development GO:0072001 225 0.077
regulation of chemotaxis GO:0050920 53 0.077
myeloid leukocyte migration GO:0097529 57 0.076
regulation of inward rectifier potassium channel activity GO:1901979 1 0.075
epithelial cell development GO:0002064 159 0.075
positive regulation of cell motility GO:2000147 116 0.075
regulation of striated muscle cell differentiation GO:0051153 81 0.074
substrate dependent cell migration GO:0006929 18 0.074
spinal cord development GO:0021510 81 0.073
Mouse
purine ribonucleoside metabolic process GO:0046128 241 0.073
regulation of g protein activated inward rectifier potassium channel activity GO:1900128 1 0.072
adult walking behavior GO:0007628 41 0.072
cerebral cortex tangential migration using cell axon interactions GO:0021824 3 0.072
heart valve morphogenesis GO:0003179 21 0.071
positive chemotaxis GO:0050918 18 0.070
organic hydroxy compound metabolic process GO:1901615 203 0.070
Mouse
organonitrogen compound catabolic process GO:1901565 264 0.070
cellular potassium ion transport GO:0071804 43 0.070
Mouse
response to organic cyclic compound GO:0014070 198 0.070
developmental cell growth GO:0048588 84 0.070
morphogenesis of a branching structure GO:0001763 203 0.069
regulation of nucleoside metabolic process GO:0009118 130 0.069
response to lipopolysaccharide GO:0032496 128 0.068
cardiac muscle contraction GO:0060048 32 0.067
kidney development GO:0001822 213 0.067
microtubule based process GO:0007017 236 0.067
regulation of cellular amino acid metabolic process GO:0006521 5 0.067
branching morphogenesis of an epithelial tube GO:0048754 159 0.066
leukocyte chemotaxis GO:0030595 69 0.066
nucleoside phosphate metabolic process GO:0006753 338 0.066
purine ribonucleotide metabolic process GO:0009150 290 0.066
organophosphate catabolic process GO:0046434 232 0.065
regulation of nucleotide metabolic process GO:0006140 169 0.065
cardiac muscle tissue development GO:0048738 130 0.064
positive regulation of programmed cell death GO:0043068 218 0.064
regulation of myotube differentiation GO:0010830 62 0.063
macromolecule methylation GO:0043414 120 0.063
regulation of transporter activity GO:0032409 57 0.063
Mouse
cellular ion homeostasis GO:0006873 165 0.063
macromolecule catabolic process GO:0009057 281 0.062
cellular amine metabolic process GO:0044106 44 0.062
nucleoside metabolic process GO:0009116 246 0.062
spleen development GO:0048536 39 0.062
heterocycle catabolic process GO:0046700 280 0.062
sequestering of calcium ion GO:0051208 18 0.062
hypothalamic tangential migration using cell axon interactions GO:0021856 3 0.061
smooth muscle cell chemotaxis GO:0071670 2 0.061
mesenchymal cell development GO:0014031 93 0.061
ossification involved in bone maturation GO:0043931 12 0.061
sensory perception of light stimulus GO:0050953 54 0.061
Mouse
detection of external stimulus GO:0009581 61 0.060
epidermis development GO:0008544 187 0.060
innate immune response GO:0045087 157 0.060
actin cytoskeleton organization GO:0030036 220 0.060
regulation of cardiac muscle contraction GO:0055117 21 0.060
purine ribonucleotide catabolic process GO:0009154 208 0.059
response to hypoxia GO:0001666 58 0.059
appendage morphogenesis GO:0035107 149 0.059
negative regulation of neuron projection development GO:0010977 50 0.058
negative regulation of cell proliferation GO:0008285 296 0.058
purine containing compound catabolic process GO:0072523 213 0.058
potassium ion import GO:0010107 1 0.057
cellular response to abiotic stimulus GO:0071214 56 0.057
protein oligomerization GO:0051259 67 0.056
calcium ion transport from endoplasmic reticulum to cytosol GO:1903514 12 0.056
sodium ion transport GO:0006814 73 0.056
multicellular organism growth GO:0035264 161 0.056
positive regulation of cardiac muscle contraction GO:0060452 2 0.056
ensheathment of neurons GO:0007272 76 0.055
cell growth GO:0016049 130 0.055
Mouse
regulation of g protein coupled receptor protein signaling pathway GO:0008277 37 0.054
phenol containing compound metabolic process GO:0018958 60 0.054
Mouse
skin development GO:0043588 220 0.054
regulation of muscle contraction GO:0006937 49 0.054
positive regulation of cellular amine metabolic process GO:0033240 5 0.054
purine nucleoside catabolic process GO:0006152 205 0.054
outflow tract morphogenesis GO:0003151 53 0.053
synapse organization GO:0050808 125 0.052
Mouse
myotube differentiation GO:0014902 105 0.052
Mouse
regulation of angiogenesis GO:0045765 81 0.052
t cell activation GO:0042110 289 0.052
nucleoside triphosphate catabolic process GO:0009143 205 0.051
positive regulation of thymocyte migration GO:2000412 2 0.050
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.050
fibronectin dependent thymocyte migration GO:0072681 1 0.050
protein autophosphorylation GO:0046777 61 0.050
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.050
regulation of apoptotic signaling pathway GO:2001233 197 0.050
regulation of calcium ion transmembrane transporter activity GO:1901019 20 0.050
cellular response to growth factor stimulus GO:0071363 197 0.049
semaphorin plexin signaling pathway GO:0071526 21 0.049
oligodendrocyte differentiation GO:0048709 53 0.049
regulation of cellular response to growth factor stimulus GO:0090287 82 0.049
amine metabolic process GO:0009308 45 0.049
mitotic cell cycle process GO:1903047 159 0.048
glial cell development GO:0021782 54 0.048
cellular metal ion homeostasis GO:0006875 151 0.047
homeostasis of number of cells GO:0048872 210 0.046
gland development GO:0048732 330 0.046
organic acid transport GO:0015849 101 0.046
Mouse
myeloid cell differentiation GO:0030099 233 0.046
positive regulation of ion transmembrane transporter activity GO:0032414 15 0.046
cell maturation GO:0048469 127 0.046
positive regulation of homeostatic process GO:0032846 64 0.046
appendage development GO:0048736 166 0.045
ribonucleoside triphosphate metabolic process GO:0009199 220 0.045
organ growth GO:0035265 117 0.045
regulation of axon extension GO:0030516 43 0.045
cardiac chamber morphogenesis GO:0003206 93 0.045
l glutamate uptake involved in synaptic transmission GO:0051935 3 0.045
positive regulation of metanephric mesenchymal cell migration GO:2000591 1 0.045
ribonucleotide catabolic process GO:0009261 208 0.045
regulation of nucleotide catabolic process GO:0030811 122 0.045
positive regulation of behavior GO:0048520 40 0.044
regulation of vasculature development GO:1901342 88 0.044
positive regulation of map kinase activity GO:0043406 84 0.044
purine ribonucleoside catabolic process GO:0046130 205 0.044
vascular process in circulatory system GO:0003018 62 0.043
eye photoreceptor cell differentiation GO:0001754 41 0.043
development of primary sexual characteristics GO:0045137 143 0.043
Worm
endochondral bone morphogenesis GO:0060350 50 0.043
cellular nitrogen compound catabolic process GO:0044270 280 0.043
nucleotide catabolic process GO:0009166 217 0.043
morphogenesis of embryonic epithelium GO:0016331 159 0.042
body morphogenesis GO:0010171 45 0.042
cerebral cortex development GO:0021987 86 0.042
response to oxidative stress GO:0006979 123 0.042
granulocyte migration GO:0097530 43 0.042
lung alveolus development GO:0048286 45 0.042
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.042
multi organism reproductive behavior GO:0044705 29 0.042
Worm
spindle localization GO:0051653 22 0.041
response to inorganic substance GO:0010035 96 0.041
neural tube formation GO:0001841 108 0.041
regulation of dendritic spine morphogenesis GO:0061001 17 0.041
cellular modified amino acid metabolic process GO:0006575 63 0.040
Mouse
purine nucleoside triphosphate catabolic process GO:0009146 203 0.040
cytosolic calcium ion transport GO:0060401 48 0.040
photoreceptor cell differentiation GO:0046530 52 0.040
negative regulation of cellular component organization GO:0051129 194 0.040
positive regulation of long term neuronal synaptic plasticity GO:0048170 3 0.040
cell division GO:0051301 120 0.040
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.040
cardiac cell development GO:0055006 41 0.040
asymmetric stem cell division GO:0098722 3 0.039
branchiomotor neuron axon guidance GO:0021785 7 0.039
ear development GO:0043583 200 0.039
organelle fission GO:0048285 170 0.039
morphogenesis of a branching epithelium GO:0061138 193 0.039
monovalent inorganic cation homeostasis GO:0055067 33 0.039
activation of immune response GO:0002253 138 0.039
regulation of homeostatic process GO:0032844 182 0.039
Mouse
myelination GO:0042552 74 0.038
ribonucleoside catabolic process GO:0042454 206 0.038
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0010880 10 0.038
detection of abiotic stimulus GO:0009582 60 0.038
regulation of potassium ion transport GO:0043266 16 0.038
Mouse
gliogenesis GO:0042063 141 0.038
cardiac muscle cell action potential GO:0086001 11 0.038
Mouse
response to molecule of bacterial origin GO:0002237 143 0.038
thymocyte migration GO:0072679 2 0.037
regulation of calcium ion transport into cytosol GO:0010522 31 0.037
central nervous system projection neuron axonogenesis GO:0021952 21 0.037
protein polymerization GO:0051258 57 0.037
rac protein signal transduction GO:0016601 13 0.037
response to insulin GO:0032868 100 0.037
retina morphogenesis in camera type eye GO:0060042 45 0.036
epithelial cell migration GO:0010631 63 0.036
bone morphogenesis GO:0060349 78 0.036
positive regulation of protein kinase activity GO:0045860 144 0.036
calcium ion transport into cytosol GO:0060402 48 0.036
aromatic compound catabolic process GO:0019439 286 0.036
organonitrogen compound biosynthetic process GO:1901566 192 0.036
regulation of positive chemotaxis GO:0050926 7 0.036
activation of mapk activity GO:0000187 59 0.036
action potential GO:0001508 78 0.036
Mouse
cardiac ventricle development GO:0003231 83 0.036
lipid biosynthetic process GO:0008610 179 0.035
organelle assembly GO:0070925 177 0.035
neuron projection extension GO:1990138 64 0.035
heart process GO:0003015 94 0.035
Zebrafish Mouse
negative regulation of phosphorus metabolic process GO:0010563 184 0.035
regulation of secretion GO:0051046 274 0.035
Mouse
regulation of intracellular transport GO:0032386 159 0.035
nucleoside phosphate biosynthetic process GO:1901293 79 0.035
ribonucleoside triphosphate catabolic process GO:0009203 199 0.035
regulation of voltage gated calcium channel activity GO:1901385 4 0.034
regulation of fat cell differentiation GO:0045598 81 0.034
positive regulation of chemotaxis GO:0050921 38 0.034
purine nucleotide catabolic process GO:0006195 211 0.034
glial cell differentiation GO:0010001 131 0.034
positive regulation of cellular catabolic process GO:0031331 148 0.034
mitral valve development GO:0003174 4 0.034
notch signaling pathway GO:0007219 71 0.034
regulation of map kinase activity GO:0043405 120 0.033
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion GO:0010881 7 0.033
regulation of organelle organization GO:0033043 289 0.033
placenta development GO:0001890 140 0.033
regulation of cell substrate adhesion GO:0010810 73 0.033
lateral inhibition GO:0046331 1 0.033
learning or memory GO:0007611 148 0.032
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.032
Mouse
sequestering of metal ion GO:0051238 19 0.032
ear morphogenesis GO:0042471 118 0.032
heart valve development GO:0003170 23 0.032
microtubule cytoskeleton organization GO:0000226 157 0.032
regulation of mapk cascade GO:0043408 248 0.032
digestive tract morphogenesis GO:0048546 147 0.032
developmental growth involved in morphogenesis GO:0060560 138 0.032
endoplasmic reticulum to cytosol transport GO:1903513 12 0.032
erythrocyte differentiation GO:0030218 88 0.032
cellular divalent inorganic cation homeostasis GO:0072503 127 0.032
substrate adhesion dependent cell spreading GO:0034446 30 0.032
canonical wnt signaling pathway GO:0060070 130 0.031
cell fate commitment GO:0045165 210 0.031
regulation of neuron differentiation GO:0045664 281 0.031
Mouse
neural crest cell development GO:0014032 48 0.031
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.031
purine nucleoside triphosphate metabolic process GO:0009144 226 0.031
lymphocyte differentiation GO:0030098 242 0.031
regulation of tissue remodeling GO:0034103 38 0.031
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.031
sensory perception of mechanical stimulus GO:0050954 107 0.030
Mouse
cytokine mediated signaling pathway GO:0019221 115 0.030
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.030
detection of stimulus involved in sensory perception GO:0050906 44 0.030
organelle localization GO:0051640 179 0.030
lymphocyte apoptotic process GO:0070227 54 0.030
striated muscle hypertrophy GO:0014897 24 0.030
cell substrate adhesion GO:0031589 130 0.030
gtp metabolic process GO:0046039 144 0.030
positive regulation of cell migration GO:0030335 109 0.030
response to peptide GO:1901652 136 0.030
peripheral nervous system development GO:0007422 53 0.030
nucleoside phosphate catabolic process GO:1901292 222 0.030
regulation of cellular component biogenesis GO:0044087 181 0.029
negative regulation of phospholipase activity GO:0010519 4 0.029
negative regulation of homeostatic process GO:0032845 71 0.029
response to peptide hormone GO:0043434 127 0.029
gamma aminobutyric acid transport GO:0015812 7 0.029
Mouse
anatomical structure maturation GO:0071695 49 0.029
Mouse
vegf activated neuropilin signaling pathway involved in axon guidance GO:1902378 1 0.029
positive regulation of calcium ion transmembrane transporter activity GO:1901021 8 0.029
positive regulation of neuron differentiation GO:0045666 141 0.029
cardiac ventricle morphogenesis GO:0003208 50 0.029
regulation of cell cycle process GO:0010564 160 0.029
trabecula morphogenesis GO:0061383 40 0.029
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.029
methylation GO:0032259 134 0.029
salivary gland morphogenesis GO:0007435 33 0.029
negative regulation of axon extension GO:0030517 19 0.029
central nervous system neuron differentiation GO:0021953 162 0.029
Mouse
facioacoustic ganglion development GO:1903375 3 0.029
regulation of reproductive process GO:2000241 66 0.029
leukocyte differentiation GO:0002521 342 0.028
extracellular matrix dependent thymocyte migration GO:0072680 1 0.028
positive regulation of muscle tissue development GO:1901863 32 0.028
regulation of thymocyte migration GO:2000410 2 0.028
response to growth factor GO:0070848 198 0.028
motor neuron axon guidance GO:0008045 26 0.028
hormone secretion GO:0046879 128 0.028
positive regulation of cell development GO:0010720 237 0.028
regulation of erythrocyte differentiation GO:0045646 23 0.028
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.028
response to reactive oxygen species GO:0000302 56 0.028
mesenchymal cell differentiation GO:0048762 107 0.028
regulation of epithelial cell migration GO:0010632 35 0.028
membrane lipid metabolic process GO:0006643 53 0.028
dephosphorylation GO:0016311 129 0.028
cd24 biosynthetic process GO:0035724 1 0.028
genitalia development GO:0048806 37 0.028
Worm
glycoprotein metabolic process GO:0009100 116 0.028
negative regulation of neuron differentiation GO:0045665 101 0.028
protein targeting GO:0006605 143 0.027
positive regulation of striated muscle contraction GO:0045989 3 0.027
fibroblast proliferation GO:0048144 35 0.027
dendrite development GO:0016358 115 0.027
Mouse
renal sodium ion transport GO:0003096 2 0.027
positive regulation of smooth muscle cell migration GO:0014911 4 0.027
regulation of purine nucleotide metabolic process GO:1900542 169 0.027
positive regulation of potassium ion transport GO:0043268 3 0.027
regulation of calcium ion transmembrane transport GO:1903169 20 0.027
cartilage development involved in endochondral bone morphogenesis GO:0060351 24 0.027
rho protein signal transduction GO:0007266 32 0.027
regulation of resting membrane potential GO:0060075 3 0.027
positive regulation of kinase activity GO:0033674 155 0.027
l glutamate import into cell GO:1990123 3 0.026
cardiac epithelial to mesenchymal transition GO:0060317 18 0.026
embryonic heart tube development GO:0035050 65 0.026
bmp signaling pathway GO:0030509 93 0.026
eosinophil migration GO:0072677 3 0.026
hypothalamus gonadotrophin releasing hormone neuron development GO:0021888 4 0.026
regulation of hydrolase activity GO:0051336 246 0.026
hepaticobiliary system development GO:0061008 67 0.026
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.025
positive regulation of muscle cell differentiation GO:0051149 39 0.025
exocrine system development GO:0035272 45 0.025
multi multicellular organism process GO:0044706 109 0.025
Worm
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.025
positive regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathway GO:0035793 1 0.025
positive regulation of potassium ion transmembrane transport GO:1901381 3 0.025
cellular response to lipid GO:0071396 145 0.024
negative regulation of phosphorylation GO:0042326 166 0.024
branching involved in salivary gland morphogenesis GO:0060445 26 0.024
positive regulation of fibronectin dependent thymocyte migration GO:2000415 1 0.024
bone maturation GO:0070977 13 0.024
posttranscriptional regulation of gene expression GO:0010608 155 0.024
ribonucleoside metabolic process GO:0009119 245 0.024
regulation of actin cytoskeleton organization GO:0032956 84 0.024
ameboidal type cell migration GO:0001667 128 0.024
negative regulation of molecular function GO:0044092 258 0.024
regulation of cell cycle GO:0051726 281 0.024
cell communication involved in cardiac conduction GO:0086065 9 0.024
Mouse
tissue migration GO:0090130 68 0.024
negative regulation of cellular amine metabolic process GO:0033239 1 0.024
wnt signaling pathway GO:0016055 188 0.024

Cacna1c disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 0 0.404
brain disease DOID:936 0 0.404
disease of anatomical entity DOID:7 0 0.404
nervous system disease DOID:863 0 0.404
myopathy DOID:423 0 0.169
muscular disease DOID:0080000 0 0.169
musculoskeletal system disease DOID:17 0 0.169
muscle tissue disease DOID:66 0 0.169
epilepsy syndrome DOID:1826 0 0.060
electroclinical syndrome DOID:0050701 0 0.060
heart disease DOID:114 0 0.058
cardiovascular system disease DOID:1287 0 0.058
cardiomyopathy DOID:0050700 0 0.025