Mus musculus

80 known processes

Cacna1s

calcium channel, voltage-dependent, L type, alpha 1S subunit

(Aliases: Cchl1a3,AW493108,Cav1.1,mdg,sj,fmd)

Cacna1s biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
striated muscle contraction GO:0006941 45 0.969
muscle system process GO:0003012 141 0.939
regulation of muscle contraction GO:0006937 49 0.870
regulation of heart contraction GO:0008016 77 0.848
Mouse
myotube differentiation GO:0014902 105 0.848
regulation of system process GO:0044057 200 0.840
Mouse
regulation of muscle system process GO:0090257 80 0.824
actin filament based movement GO:0030048 23 0.816
muscle cell development GO:0055001 133 0.795
myotube cell development GO:0014904 60 0.795
muscle contraction GO:0006936 101 0.795
maintenance of location GO:0051235 89 0.783
heart process GO:0003015 94 0.774
Mouse
cellular metal ion homeostasis GO:0006875 151 0.728
Mouse
regulation of skeletal muscle adaptation GO:0014733 12 0.724
inorganic ion transmembrane transport GO:0098660 234 0.717
cardiac muscle contraction GO:0060048 32 0.712
striated muscle tissue development GO:0014706 293 0.694
calcium ion transport GO:0006816 159 0.691
ventricular cardiac muscle cell action potential GO:0086005 4 0.679
skeletal muscle organ development GO:0060538 163 0.664
heart contraction GO:0060047 93 0.645
Mouse
actin cytoskeleton organization GO:0030036 220 0.634
calcium ion transmembrane transport GO:0070588 85 0.627
striated muscle cell development GO:0055002 125 0.626
inorganic cation transmembrane transport GO:0098662 207 0.597
sequestering of calcium ion GO:0051208 18 0.596
cation homeostasis GO:0055080 212 0.586
Mouse
muscle adaptation GO:0043500 39 0.571
metal ion homeostasis GO:0055065 189 0.560
Mouse
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0010880 10 0.550
actin mediated cell contraction GO:0070252 15 0.546
skeletal muscle fiber development GO:0048741 58 0.542
cellular divalent inorganic cation homeostasis GO:0072503 127 0.517
Mouse
actomyosin structure organization GO:0031032 56 0.511
positive regulation of heart rate GO:0010460 10 0.505
skeletal muscle adaptation GO:0043501 16 0.493
cellular chemical homeostasis GO:0055082 215 0.491
Mouse
sequestering of metal ion GO:0051238 19 0.482
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014808 12 0.469
transmembrane transport GO:0055085 412 0.459
release of sequestered calcium ion into cytosol GO:0051209 42 0.455
cardiac muscle cell contraction GO:0086003 7 0.452
positive regulation of cardiac muscle contraction GO:0060452 2 0.445
cellular component assembly involved in morphogenesis GO:0010927 139 0.440
canonical wnt signaling pathway GO:0060070 130 0.428
calcium ion transport into cytosol GO:0060402 48 0.415
blood circulation GO:0008015 195 0.413
Mouse
positive regulation of blood circulation GO:1903524 22 0.412
muscle tissue development GO:0060537 308 0.408
cation transmembrane transport GO:0098655 266 0.403
skeletal system development GO:0001501 356 0.393
regulation of ion transmembrane transport GO:0034765 119 0.388
positive regulation of ryanodine sensitive calcium release channel activity GO:0060316 1 0.374
transition between fast and slow fiber GO:0014883 9 0.358
response to inactivity GO:0014854 4 0.356
regulation of membrane potential GO:0042391 192 0.355
Mouse
muscle cell differentiation GO:0042692 261 0.350
response to organic cyclic compound GO:0014070 198 0.345
cytoplasmic transport GO:0016482 234 0.341
regulation of striated muscle contraction GO:0006942 25 0.339
regulation of actin filament based process GO:0032970 99 0.331
circulatory system process GO:0003013 197 0.328
Mouse
regulation of ion transport GO:0043269 215 0.321
muscle fiber development GO:0048747 76 0.318
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion GO:0010881 7 0.314
positive regulation of calcium ion transport GO:0051928 27 0.304
regulation of cardiac muscle contraction GO:0055117 21 0.299
organelle assembly GO:0070925 177 0.298
cytosolic calcium ion transport GO:0060401 48 0.296
regulation of cardiac muscle contraction by calcium ion signaling GO:0010882 9 0.289
divalent metal ion transport GO:0070838 172 0.288
endoplasmic reticulum to cytosol transport GO:1903513 12 0.283
actin filament organization GO:0007015 113 0.276
cation transport GO:0006812 399 0.272
cellular response to organic cyclic compound GO:0071407 87 0.271
regulation of ion homeostasis GO:2000021 64 0.271
positive regulation of heart contraction GO:0045823 14 0.266
regulation of intracellular transport GO:0032386 159 0.261
regulation of transmembrane transport GO:0034762 128 0.261
nucleoside phosphate metabolic process GO:0006753 338 0.258
regulation of ryanodine sensitive calcium release channel activity GO:0060314 10 0.246
ribonucleotide catabolic process GO:0009261 208 0.241
synaptic transmission GO:0007268 329 0.238
Mouse
calcium ion transport from endoplasmic reticulum to cytosol GO:1903514 12 0.238
calcium ion homeostasis GO:0055074 127 0.232
Mouse
myosin filament organization GO:0031033 3 0.230
purine containing compound metabolic process GO:0072521 311 0.229
muscle tissue morphogenesis GO:0060415 53 0.224
response to organonitrogen compound GO:0010243 246 0.221
regulation of heart rate GO:0002027 36 0.219
Mouse
divalent inorganic cation homeostasis GO:0072507 138 0.215
Mouse
cell type specific apoptotic process GO:0097285 268 0.213
Mouse
organophosphate catabolic process GO:0046434 232 0.211
cardiac chamber morphogenesis GO:0003206 93 0.211
muscle filament sliding GO:0030049 1 0.209
monocarboxylic acid metabolic process GO:0032787 191 0.207
striated muscle myosin thick filament assembly GO:0071688 1 0.207
regulation of feeding behavior GO:0060259 3 0.206
Worm
regulation of calcium ion transmembrane transporter activity GO:1901019 20 0.206
ribose phosphate metabolic process GO:0019693 291 0.205
regulation of calcium ion transport GO:0051924 69 0.204
Mouse
cardiac muscle tissue morphogenesis GO:0055008 44 0.204
regulation of muscle adaptation GO:0043502 31 0.203
glycosyl compound metabolic process GO:1901657 246 0.201
regulation of purine nucleotide metabolic process GO:1900542 169 0.200
multicellular organismal signaling GO:0035637 91 0.196
Mouse
nucleotide metabolic process GO:0009117 332 0.196
cellular homeostasis GO:0019725 240 0.190
Mouse
positive regulation of striated muscle contraction GO:0045989 3 0.190
g protein coupled receptor signaling pathway involved in heart process GO:0086103 4 0.185
carbohydrate metabolic process GO:0005975 230 0.181
Mouse
cytosolic calcium ion homeostasis GO:0051480 70 0.177
Mouse
heart morphogenesis GO:0003007 178 0.175
ribonucleoside triphosphate catabolic process GO:0009203 199 0.175
regulation of actin cytoskeleton organization GO:0032956 84 0.171
regulation of cation channel activity GO:2001257 22 0.168
skeletal myofibril assembly GO:0014866 4 0.168
syncytium formation by plasma membrane fusion GO:0000768 42 0.167
regulation of cytoskeleton organization GO:0051493 122 0.166
regulation of skeletal muscle contraction GO:0014819 3 0.166
regulation of homeostatic process GO:0032844 182 0.163
Mouse
ribonucleoside catabolic process GO:0042454 206 0.157
adrenergic receptor signaling pathway GO:0071875 13 0.152
regulation of calcium ion transmembrane transport GO:1903169 20 0.152
positive regulation of muscle contraction GO:0045933 10 0.151
atp metabolic process GO:0046034 75 0.151
positive regulation of ion transport GO:0043270 65 0.147
cellular response to lipid GO:0071396 145 0.147
sarcomere organization GO:0045214 24 0.146
cardiac muscle tissue development GO:0048738 130 0.146
cellular ion homeostasis GO:0006873 165 0.143
Mouse
nucleoside metabolic process GO:0009116 246 0.143
action potential GO:0001508 78 0.142
Mouse
response to oxidative stress GO:0006979 123 0.142
cellular calcium ion homeostasis GO:0006874 119 0.142
Mouse
regulation of calcium ion transport into cytosol GO:0010522 31 0.137
purine nucleoside triphosphate metabolic process GO:0009144 226 0.137
bone development GO:0060348 120 0.136
heterocycle catabolic process GO:0046700 280 0.135
skeletal muscle thin filament assembly GO:0030240 2 0.135
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.134
regulation of transporter activity GO:0032409 57 0.132
Mouse
purine nucleotide metabolic process GO:0006163 302 0.130
purine ribonucleoside metabolic process GO:0046128 241 0.130
ion transmembrane transport GO:0034220 361 0.129
myosin filament assembly GO:0031034 2 0.127
second messenger mediated signaling GO:0019932 73 0.125
purine containing compound catabolic process GO:0072523 213 0.125
regulation of cellular catabolic process GO:0031329 242 0.124
purine ribonucleotide metabolic process GO:0009150 290 0.123
regulation of organelle organization GO:0033043 289 0.123
regulation of heart rate by chemical signal GO:0003062 4 0.122
epithelial tube morphogenesis GO:0060562 303 0.121
skeletal muscle myosin thick filament assembly GO:0030241 1 0.121
purine nucleoside catabolic process GO:0006152 205 0.119
bmp signaling pathway GO:0030509 93 0.119
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.117
nucleoside catabolic process GO:0009164 206 0.116
regulation of cytoplasmic transport GO:1903649 112 0.115
ribonucleoside monophosphate metabolic process GO:0009161 80 0.113
regulation of apoptotic signaling pathway GO:2001233 197 0.112
cardiac muscle cell differentiation GO:0055007 69 0.111
divalent inorganic cation transport GO:0072511 178 0.107
cardiac chamber development GO:0003205 108 0.107
cellular amino acid metabolic process GO:0006520 103 0.106
Mouse
organonitrogen compound catabolic process GO:1901565 264 0.105
response to lipopolysaccharide GO:0032496 128 0.102
ossification GO:0001503 216 0.102
nucleoside monophosphate metabolic process GO:0009123 85 0.101
locomotory behavior GO:0007626 195 0.101
Mouse
cardiac muscle cell action potential involved in contraction GO:0086002 6 0.098
peptidyl amino acid modification GO:0018193 336 0.096
regulation of myotube differentiation GO:0010830 62 0.096
regulation of metal ion transport GO:0010959 106 0.095
Mouse
atp catabolic process GO:0006200 55 0.093
response to alkaloid GO:0043279 34 0.093
embryonic organ morphogenesis GO:0048562 276 0.092
feeding behavior GO:0007631 62 0.091
Worm
fatty acid metabolic process GO:0006631 121 0.091
skin development GO:0043588 220 0.091
regulation of striated muscle cell differentiation GO:0051153 81 0.091
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.090
negative regulation of homeostatic process GO:0032845 71 0.090
nucleobase containing small molecule metabolic process GO:0055086 352 0.090
response to molecule of bacterial origin GO:0002237 143 0.090
myotube differentiation involved in skeletal muscle regeneration GO:0014908 2 0.089
purine nucleoside metabolic process GO:0042278 241 0.089
response to activity GO:0014823 13 0.088
mitochondrion organization GO:0007005 134 0.088
regulation of blood circulation GO:1903522 93 0.087
Mouse
regulation of actin filament based movement GO:1903115 12 0.087
aromatic compound catabolic process GO:0019439 286 0.087
cardiac muscle cell development GO:0055013 39 0.086
wnt signaling pathway GO:0016055 188 0.081
protein localization to organelle GO:0033365 185 0.081
carbohydrate derivative catabolic process GO:1901136 231 0.080
cardiac ventricle development GO:0003231 83 0.079
ossification involved in bone maturation GO:0043931 12 0.079
nucleotide catabolic process GO:0009166 217 0.079
nucleoside triphosphate metabolic process GO:0009141 230 0.079
purine ribonucleoside catabolic process GO:0046130 205 0.078
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.078
actin myosin filament sliding GO:0033275 1 0.077
purine nucleotide catabolic process GO:0006195 211 0.077
cartilage development GO:0051216 140 0.076
nucleoside triphosphate catabolic process GO:0009143 205 0.076
response to decreased oxygen levels GO:0036293 59 0.076
purine nucleoside monophosphate catabolic process GO:0009128 58 0.075
ribonucleotide metabolic process GO:0009259 291 0.074
inflammatory response GO:0006954 244 0.074
cell communication involved in cardiac conduction GO:0086065 9 0.074
Mouse
response to temperature stimulus GO:0009266 55 0.072
positive regulation of ion transmembrane transport GO:0034767 24 0.071
fatty acid biosynthetic process GO:0006633 41 0.071
protein catabolic process GO:0030163 221 0.071
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.071
muscle hypertrophy GO:0014896 24 0.070
regulation of the force of heart contraction GO:0002026 17 0.070
regulation of response to wounding GO:1903034 189 0.070
positive regulation of transmembrane transport GO:0034764 29 0.069
macromolecule catabolic process GO:0009057 281 0.068
regulation of atp catabolic process GO:1903289 9 0.068
cardiac ventricle morphogenesis GO:0003208 50 0.067
embryonic heart tube morphogenesis GO:0003143 51 0.067
cellular nitrogen compound catabolic process GO:0044270 280 0.066
lipid localization GO:0010876 126 0.066
positive regulation of calcium ion transmembrane transporter activity GO:1901021 8 0.066
regulation of cell cycle process GO:0010564 160 0.065
cellular amine metabolic process GO:0044106 44 0.064
sensory perception GO:0007600 245 0.064
Mouse
regulation of nucleoside metabolic process GO:0009118 130 0.063
nucleoside monophosphate catabolic process GO:0009125 59 0.063
positive regulation of cell death GO:0010942 224 0.063
learning or memory GO:0007611 148 0.061
Mouse
smooth muscle contraction GO:0006939 44 0.061
Mouse
regulation of cytokine production GO:0001817 266 0.061
organic cyclic compound catabolic process GO:1901361 295 0.061
cardiac muscle fiber development GO:0048739 4 0.061
regulation of reproductive process GO:2000241 66 0.060
myofibril assembly GO:0030239 34 0.060
respiratory tube development GO:0030323 167 0.059
ventricular cardiac muscle tissue morphogenesis GO:0055010 32 0.058
positive regulation of cytokine production GO:0001819 174 0.058
cellular response to hormone stimulus GO:0032870 150 0.058
purine nucleoside triphosphate catabolic process GO:0009146 203 0.058
response to radiation GO:0009314 165 0.058
Mouse
sensory perception of light stimulus GO:0050953 54 0.057
Mouse
regulation of cardiac muscle cell contraction GO:0086004 11 0.057
regulation of interleukin 6 production GO:0032675 55 0.057
regulation of nucleotide catabolic process GO:0030811 122 0.057
nucleoside phosphate catabolic process GO:1901292 222 0.057
neuron death GO:0070997 154 0.056
Mouse
oxidation reduction process GO:0055114 342 0.056
endomembrane system organization GO:0010256 147 0.056
striated muscle hypertrophy GO:0014897 24 0.056
organ maturation GO:0048799 17 0.056
response to hypoxia GO:0001666 58 0.055
ribonucleoside monophosphate catabolic process GO:0009158 57 0.055
regulation of skeletal muscle fiber development GO:0048742 36 0.054
extracellular matrix organization GO:0030198 147 0.054
response to light stimulus GO:0009416 135 0.054
Mouse
positive regulation of cell cycle GO:0045787 92 0.053
sperm motility GO:0030317 47 0.053
Mouse
response to denervation involved in regulation of muscle adaptation GO:0014894 4 0.052
embryonic heart tube development GO:0035050 65 0.051
regulation of sarcomere organization GO:0060297 4 0.051
sodium ion transport GO:0006814 73 0.051
positive regulation of programmed cell death GO:0043068 218 0.051
protein modification by small protein conjugation GO:0032446 187 0.050
leukocyte mediated immunity GO:0002443 174 0.050
left ventricular cardiac muscle tissue morphogenesis GO:0003220 2 0.049
multicellular organismal movement GO:0050879 16 0.049
Mouse
positive regulation of ion transmembrane transporter activity GO:0032414 15 0.049
bone maturation GO:0070977 13 0.049
myeloid cell differentiation GO:0030099 233 0.048
nuclear division GO:0000280 158 0.048
protein oligomerization GO:0051259 67 0.048
regulation of myoblast differentiation GO:0045661 29 0.047
positive regulation of cellular amine metabolic process GO:0033240 5 0.047
cardiac myofibril assembly GO:0055003 12 0.046
glycosyl compound catabolic process GO:1901658 206 0.046
response to muscle inactivity GO:0014870 4 0.046
cell cell signaling involved in cardiac conduction GO:0086019 6 0.046
Mouse
regulation of chemotaxis GO:0050920 53 0.045
striated muscle adaptation GO:0014888 26 0.045
cellular response to growth factor stimulus GO:0071363 197 0.045
purine ribonucleotide catabolic process GO:0009154 208 0.045
regulation of hydrolase activity GO:0051336 246 0.045
negative regulation of cell proliferation GO:0008285 296 0.044
regulation of purine nucleotide catabolic process GO:0033121 122 0.043
calcium mediated signaling GO:0019722 46 0.043
axonal fasciculation GO:0007413 15 0.043
lipid storage GO:0019915 36 0.042
relaxation of muscle GO:0090075 18 0.042
response to muscle inactivity involved in regulation of muscle adaptation GO:0014877 4 0.042
response to growth factor GO:0070848 198 0.042
carboxylic acid biosynthetic process GO:0046394 86 0.042
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.041
musculoskeletal movement GO:0050881 16 0.041
Mouse
muscle atrophy GO:0014889 3 0.041
cardiac left ventricle morphogenesis GO:0003214 9 0.041
cell fate commitment GO:0045165 210 0.041
negative regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061179 4 0.041
regulation of morphogenesis of a branching structure GO:0060688 53 0.041
cellular ketone metabolic process GO:0042180 84 0.040
regulation of cellular component biogenesis GO:0044087 181 0.040
myoblast proliferation GO:0051450 11 0.040
regulation of secretion by cell GO:1903530 249 0.040
Mouse
chemotaxis GO:0006935 247 0.040
regulation of proteolysis GO:0030162 164 0.040
sensory organ morphogenesis GO:0090596 242 0.039
cytokine metabolic process GO:0042107 71 0.039
regulation of nucleotide metabolic process GO:0006140 169 0.039
carboxylic acid transport GO:0046942 100 0.038
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 220 0.038
regulation of neuron death GO:1901214 134 0.037
Mouse
negative regulation of defense response GO:0031348 77 0.037
regulation of cellular amino acid metabolic process GO:0006521 5 0.037
defecation GO:0030421 1 0.036
protein localization to membrane GO:0072657 108 0.036
Mouse
cellular lipid metabolic process GO:0044255 323 0.036
regulation of interferon gamma production GO:0032649 57 0.036
morphogenesis of a branching structure GO:0001763 203 0.035
adult locomotory behavior GO:0008344 91 0.035
Mouse
response to inorganic substance GO:0010035 96 0.035
ribonucleoside metabolic process GO:0009119 245 0.035
visual perception GO:0007601 52 0.035
Mouse
regulation of cellular response to stress GO:0080135 159 0.035
apoptotic signaling pathway GO:0097190 306 0.035
immune effector process GO:0002252 321 0.035
regulation of ion transmembrane transporter activity GO:0032412 54 0.035
Mouse
morphogenesis of a branching epithelium GO:0061138 193 0.035
positive regulation of cation channel activity GO:2001259 8 0.034
cardiocyte differentiation GO:0035051 87 0.034
cytokine production GO:0001816 319 0.034
microtubule based process GO:0007017 236 0.034
nuclear transport GO:0051169 139 0.034
cellular response to biotic stimulus GO:0071216 92 0.034
chromatin organization GO:0006325 206 0.034
cardiac cell development GO:0055006 41 0.034
regulation of defense response GO:0031347 233 0.034
mrna processing GO:0006397 63 0.033
extracellular structure organization GO:0043062 148 0.033
t cell activation GO:0042110 289 0.033
detection of abiotic stimulus GO:0009582 60 0.033
regulation of kinase activity GO:0043549 249 0.033
negative regulation of protein modification process GO:0031400 163 0.033
protein ubiquitination GO:0016567 171 0.033
regulation of cell substrate adhesion GO:0010810 73 0.033
negative regulation of cellular protein metabolic process GO:0032269 247 0.033
purine nucleoside monophosphate metabolic process GO:0009126 81 0.032
ventricular cardiac myofibril assembly GO:0055005 3 0.032
lipoprotein metabolic process GO:0042157 43 0.032
ventricular cardiac muscle tissue development GO:0003229 38 0.032
positive regulation of skeletal muscle tissue regeneration GO:0043415 4 0.032
positive regulation of t cell proliferation GO:0042102 52 0.032
striated muscle atrophy GO:0014891 2 0.032
anion transport GO:0006820 177 0.032
Mouse
cellular response to molecule of bacterial origin GO:0071219 83 0.032
adaptive immune response GO:0002250 155 0.031
posttranscriptional regulation of gene expression GO:0010608 155 0.031
regulation of synaptic activity GO:0060025 1 0.031
gonad development GO:0008406 141 0.031
Worm
response to nutrient levels GO:0031667 109 0.031
polysaccharide metabolic process GO:0005976 39 0.031
regulation of establishment of protein localization GO:0070201 181 0.031
positive regulation of apoptotic process GO:0043065 217 0.031
neural tube development GO:0021915 160 0.031
axon guidance GO:0007411 141 0.031
mature dendritic cell differentiation GO:0097029 3 0.031
gland development GO:0048732 330 0.031
regulation of embryonic development GO:0045995 71 0.030
regulation of atp metabolic process GO:1903578 17 0.030
spleen development GO:0048536 39 0.030
cellular macromolecule catabolic process GO:0044265 206 0.030
nucleocytoplasmic transport GO:0006913 139 0.030
response to stimulus involved in regulation of muscle adaptation GO:0014874 6 0.030
negative regulation of neuron apoptotic process GO:0043524 92 0.030
Mouse
neurotransmitter transport GO:0006836 76 0.029
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.029
cellular protein complex assembly GO:0043623 116 0.029
regulation of protein stability GO:0031647 52 0.029
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.029
Mouse
cytokinetic process GO:0032506 2 0.029
defense response to other organism GO:0098542 197 0.029
male gamete generation GO:0048232 285 0.029
multicellular organismal reproductive behavior GO:0033057 23 0.029
Worm
developmental cell growth GO:0048588 84 0.028
positive regulation of striated muscle cell differentiation GO:0051155 35 0.028
development of primary sexual characteristics GO:0045137 143 0.028
Worm
cerebellum development GO:0021549 77 0.028
Mouse
t cell proliferation GO:0042098 120 0.028
negative regulation of apoptotic signaling pathway GO:2001234 104 0.028
cellular response to steroid hormone stimulus GO:0071383 33 0.028
negative regulation of molecular function GO:0044092 258 0.028
protein processing GO:0016485 163 0.028
protein modification by small protein conjugation or removal GO:0070647 207 0.028
nitrogen compound transport GO:0071705 271 0.028
Mouse
regulation of wnt signaling pathway GO:0030111 123 0.027
regulation of multi organism process GO:0043900 111 0.027
regulation of lymphocyte activation GO:0051249 240 0.027
cellular response to dna damage stimulus GO:0006974 207 0.027
outflow tract morphogenesis GO:0003151 53 0.027
leukocyte chemotaxis GO:0030595 69 0.027
regulation of protein localization GO:0032880 231 0.027
positive regulation of protein modification process GO:0031401 299 0.027
membrane organization GO:0061024 245 0.026
Mouse
glial cell differentiation GO:0010001 131 0.026
mrna splicing via spliceosome GO:0000398 43 0.026
skeletal muscle cell differentiation GO:0035914 66 0.026
protein maturation GO:0051604 176 0.026
carbohydrate catabolic process GO:0016052 32 0.026
meiotic cell cycle GO:0051321 122 0.026
somite development GO:0061053 81 0.026
skeletal system morphogenesis GO:0048705 203 0.026
plasma membrane organization GO:0007009 90 0.026
embryonic epithelial tube formation GO:0001838 130 0.026
response to insulin GO:0032868 100 0.026
positive regulation of muscle adaptation GO:0014744 2 0.026
spermatogenesis GO:0007283 284 0.026
lipid transport GO:0006869 98 0.025
response to purine containing compound GO:0014074 28 0.025
regulation of monocyte chemotaxis GO:0090025 3 0.025
negative regulation of protein metabolic process GO:0051248 282 0.025
positive regulation of leukocyte proliferation GO:0070665 73 0.025
liver development GO:0001889 66 0.025
renal system process GO:0003014 48 0.025
Mouse
endocytosis GO:0006897 168 0.025
muscle cell fate specification GO:0042694 1 0.025
connective tissue development GO:0061448 179 0.025
dephosphorylation GO:0016311 129 0.025
myoblast differentiation GO:0045445 52 0.025
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.025
regulation of body fluid levels GO:0050878 162 0.025
regulation of anatomical structure size GO:0090066 178 0.025
Mouse
positive regulation of mitochondrial calcium ion concentration GO:0051561 3 0.025
phosphatidylethanolamine biosynthetic process GO:0006646 2 0.024
amine metabolic process GO:0009308 45 0.024
generation of precursor metabolites and energy GO:0006091 103 0.024
regulation of cell cycle GO:0051726 281 0.024
regulation of syncytium formation by plasma membrane fusion GO:0060142 23 0.024
fat cell differentiation GO:0045444 160 0.024
positive regulation of protein phosphorylation GO:0001934 242 0.024
regulation of sodium ion transport GO:0002028 29 0.023
regulation of mrna metabolic process GO:1903311 43 0.023
regulation of cellular amine metabolic process GO:0033238 20 0.023
somite specification GO:0001757 4 0.023
positive regulation of secretion by cell GO:1903532 114 0.023
leukocyte activation involved in immune response GO:0002366 126 0.023
positive regulation of muscle cell differentiation GO:0051149 39 0.023
hair follicle development GO:0001942 85 0.023
circadian sleep wake cycle rem sleep GO:0042747 1 0.023
regulation of leukocyte proliferation GO:0070663 121 0.023
peptide transport GO:0015833 133 0.023
Mouse
transmission of nerve impulse GO:0019226 76 0.023
Mouse
positive regulation of hydrolase activity GO:0051345 148 0.023
mitotic cell cycle GO:0000278 195 0.023
negative regulation of cytoskeleton organization GO:0051494 36 0.023
interleukin 12 secretion GO:0072610 3 0.023
detection of stimulus GO:0051606 84 0.022
protein import into nucleus GO:0006606 95 0.022
response to extracellular stimulus GO:0009991 127 0.022
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.022
neural tube closure GO:0001843 90 0.022
regulation of voltage gated calcium channel activity GO:1901385 4 0.022
stem cell differentiation GO:0048863 268 0.022
cytokine biosynthetic process GO:0042089 68 0.022
positive regulation of cell cycle process GO:0090068 61 0.022
negative regulation of organelle organization GO:0010639 90 0.022
regulation of systemic arterial blood pressure GO:0003073 61 0.022
organic acid transport GO:0015849 101 0.022
Mouse
regulation of cell activation GO:0050865 289 0.022
negative regulation of wnt signaling pathway GO:0030178 73 0.022
positive regulation of cell activation GO:0050867 158 0.022
negative regulation of immune system process GO:0002683 209 0.022
substantia nigra development GO:0021762 2 0.022
nuclear import GO:0051170 95 0.022
cell adhesion GO:0007155 329 0.022
ras protein signal transduction GO:0007265 77 0.022
epithelial cell proliferation GO:0050673 174 0.022
positive regulation of skeletal muscle fiber development GO:0048743 3 0.022
regulation of neuron apoptotic process GO:0043523 122 0.022
Mouse

Cacna1s disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
muscular disease DOID:0080000 0 0.969
disease of anatomical entity DOID:7 0 0.969
musculoskeletal system disease DOID:17 0 0.969
muscle tissue disease DOID:66 0 0.969
myopathy DOID:423 0 0.539
distal arthrogryposis DOID:0050646 0 0.395
nervous system disease DOID:863 0 0.093
cardiovascular system disease DOID:1287 0 0.039
retinal disease DOID:5679 0 0.038
sensory system disease DOID:0050155 0 0.038
eye and adnexa disease DOID:1492 0 0.038
eye disease DOID:5614 0 0.038