|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.977
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.935
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.917
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.910
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.844
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.819
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.800
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.784
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.759
|
Zebrafish |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.759
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.758
|
Mouse |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.753
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.748
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.747
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.732
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.717
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.690
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.688
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.670
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.664
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.653
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.648
|
Zebrafish |
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.642
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.639
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.633
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.599
|
Mouse |
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.588
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.580
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.555
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.548
|
|
|
|
mitral valve morphogenesis
|
GO:0003183 |
4 |
0.525
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.496
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.494
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.491
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.486
|
|
|
|
aortic valve morphogenesis
|
GO:0003180 |
4 |
0.479
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.478
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.474
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.473
|
Mouse |
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.471
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.469
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.444
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.444
|
|
|
|
mesenchyme development
|
GO:0060485 |
152 |
0.429
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.429
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.425
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.423
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.412
|
Mouse |
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.406
|
|
|
|
positive regulation of muscle cell differentiation
|
GO:0051149 |
39 |
0.406
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
149 |
0.404
|
|
|
|
endocardial cushion to mesenchymal transition involved in heart valve formation
|
GO:0003199 |
4 |
0.400
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
3 |
0.395
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.390
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.389
|
Mouse |
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.387
|
Mouse |
|
|
forebrain development
|
GO:0030900 |
302 |
0.377
|
Zebrafish Mouse Rat |
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.375
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.374
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.373
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.370
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.365
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.355
|
|
|
|
embryonic appendage morphogenesis
|
GO:0035113 |
126 |
0.351
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.350
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.350
|
Zebrafish |
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.345
|
|
|
|
thymic t cell selection
|
GO:0045061 |
22 |
0.342
|
Mouse |
|
|
syncytium formation
|
GO:0006949 |
43 |
0.338
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.336
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.328
|
Mouse |
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.320
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.320
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.317
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.310
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.305
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.304
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.304
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.293
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.289
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.288
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.286
|
Mouse |
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.285
|
|
|
|
myeloid dendritic cell activation
|
GO:0001773 |
25 |
0.285
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.279
|
Mouse |
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.279
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
93 |
0.278
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.275
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.274
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.273
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.269
|
Mouse |
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.268
|
Mouse |
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.268
|
|
|
|
cardiocyte differentiation
|
GO:0035051 |
87 |
0.267
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.266
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.256
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.249
|
Mouse |
|
|
neuron death
|
GO:0070997 |
154 |
0.247
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
58 |
0.246
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.245
|
|
|
|
positive regulation of striated muscle cell differentiation
|
GO:0051155 |
35 |
0.243
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.240
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
81 |
0.240
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.240
|
Zebrafish |
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.238
|
Mouse |
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.236
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.228
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.226
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.226
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.222
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.220
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.216
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.214
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.213
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.213
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.212
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.211
|
Mouse |
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.211
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.210
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.209
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.208
|
Zebrafish |
|
|
embryonic skeletal system development
|
GO:0048706 |
120 |
0.205
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.204
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.203
|
Mouse |
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.202
|
Mouse |
|
|
immune effector process
|
GO:0002252 |
321 |
0.200
|
Mouse |
|
|
male gamete generation
|
GO:0048232 |
285 |
0.199
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.199
|
Mouse |
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.198
|
|
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
14 |
0.197
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.196
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.194
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.193
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.192
|
|
|
|
negative regulation of leukocyte proliferation
|
GO:0070664 |
46 |
0.191
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.189
|
Zebrafish Mouse |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.186
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.184
|
|
|
|
hematopoietic stem cell migration
|
GO:0035701 |
1 |
0.183
|
Mouse |
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.182
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.182
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.182
|
|
|
|
methylation
|
GO:0032259 |
134 |
0.181
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.181
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.180
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.179
|
|
|
|
endocardial cushion to mesenchymal transition
|
GO:0090500 |
5 |
0.177
|
|
|
|
retinal ganglion cell axon guidance
|
GO:0031290 |
18 |
0.177
|
Zebrafish |
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.175
|
|
|
|
cartilage development
|
GO:0051216 |
140 |
0.175
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
61 |
0.175
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.172
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.170
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.170
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.169
|
Mouse |
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.168
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.167
|
Zebrafish |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.166
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.166
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.166
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
42 |
0.163
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.163
|
|
|
|
developmental cell growth
|
GO:0048588 |
84 |
0.163
|
Zebrafish |
|
|
ossification
|
GO:0001503 |
216 |
0.162
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.161
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.160
|
Mouse |
|
|
cellular response to glucose stimulus
|
GO:0071333 |
45 |
0.159
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.159
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.159
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.155
|
Mouse |
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.154
|
Mouse |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.154
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
107 |
0.153
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.151
|
Mouse Rat |
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.151
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.149
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.148
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.148
|
Mouse |
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.148
|
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.147
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.147
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.147
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.147
|
|
|
|
negative regulation of dendritic spine morphogenesis
|
GO:0061002 |
3 |
0.147
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.146
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.146
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.144
|
Mouse |
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.144
|
|
|
|
neural crest cell differentiation
|
GO:0014033 |
54 |
0.144
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.143
|
Mouse |
|
|
apoptotic cell clearance
|
GO:0043277 |
17 |
0.143
|
|
|
|
endothelial cell migration
|
GO:0043542 |
44 |
0.141
|
Zebrafish |
|
|
photoreceptor cell development
|
GO:0042461 |
40 |
0.141
|
|
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.141
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.140
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.140
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.139
|
|
|
|
negative regulation of neuron projection development
|
GO:0010977 |
50 |
0.139
|
|
|
|
axon target recognition
|
GO:0007412 |
4 |
0.138
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.137
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.137
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
52 |
0.137
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.136
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.136
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.135
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.135
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.135
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.133
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.133
|
|
|
|
neuron projection extension
|
GO:1990138 |
64 |
0.132
|
Zebrafish |
|
|
cellular response to monosaccharide stimulus
|
GO:0071326 |
47 |
0.132
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.132
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.132
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.132
|
Zebrafish Mouse |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.131
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.131
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.131
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.129
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.129
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.128
|
Mouse |
|
|
inflammatory response
|
GO:0006954 |
244 |
0.128
|
Mouse |
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.128
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.128
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.128
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.127
|
Mouse |
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.127
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
59 |
0.127
|
Zebrafish |
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.127
|
|
|
|
regulation of cell size
|
GO:0008361 |
72 |
0.126
|
Zebrafish |
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.126
|
Mouse |
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.125
|
Zebrafish |
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.125
|
Mouse Rat |
|
|
negative regulation of cell motility
|
GO:2000146 |
61 |
0.125
|
Zebrafish |
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.125
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.125
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
83 |
0.124
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.123
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.122
|
Mouse |
|
|
cell division
|
GO:0051301 |
120 |
0.121
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.120
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.120
|
|
|
|
limb development
|
GO:0060173 |
166 |
0.120
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.120
|
Mouse |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.120
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.119
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.119
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.118
|
|
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.118
|
Human |
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
72 |
0.117
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.116
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.116
|
Mouse |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.115
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.115
|
Mouse |
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.113
|
Mouse |
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.113
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.112
|
Mouse |
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.112
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.112
|
Mouse |
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.111
|
Mouse |
|
|
regulation of postsynaptic membrane potential
|
GO:0060078 |
48 |
0.111
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.110
|
Zebrafish |
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.109
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.109
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.109
|
Mouse |
|
|
negative regulation of neuron death
|
GO:1901215 |
98 |
0.109
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
39 |
0.107
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.107
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
53 |
0.107
|
Human Zebrafish Mouse Rat |
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.107
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.106
|
|
|
|
regulation of keratinocyte proliferation
|
GO:0010837 |
15 |
0.105
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.103
|
|
|
|
response to drug
|
GO:0042493 |
75 |
0.103
|
|
|
|
negative regulation of b cell activation
|
GO:0050869 |
27 |
0.103
|
|
|
|
establishment of t cell polarity
|
GO:0001768 |
2 |
0.103
|
|
|
|
smoothened signaling pathway
|
GO:0007224 |
105 |
0.102
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.102
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.102
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.102
|
Human Mouse Rat |
|
|
skeletal system development
|
GO:0001501 |
356 |
0.101
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.101
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.101
|
Mouse |
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.101
|
Mouse |
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.100
|
Mouse |
|
|
negative regulation of neuron differentiation
|
GO:0045665 |
101 |
0.100
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.100
|
Mouse |
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.099
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.099
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
67 |
0.099
|
|
|
|
regulation of b cell differentiation
|
GO:0045577 |
23 |
0.099
|
|
|
|
cellular response to hexose stimulus
|
GO:0071331 |
47 |
0.098
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.098
|
|
|
|
cellular response to carbohydrate stimulus
|
GO:0071322 |
50 |
0.097
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.097
|
Mouse |
|
|
multicellular organismal aging
|
GO:0010259 |
24 |
0.097
|
|
|
|
endochondral bone morphogenesis
|
GO:0060350 |
50 |
0.095
|
|
|
|
regulation of epithelial to mesenchymal transition
|
GO:0010717 |
22 |
0.095
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.094
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.094
|
|
|
|
positive regulation of monocyte chemotaxis
|
GO:0090026 |
2 |
0.094
|
Mouse |
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.094
|
Zebrafish Mouse |
|
|
cellular response to oxidative stress
|
GO:0034599 |
76 |
0.093
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.093
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
41 |
0.093
|
|
|
|
regulation of protein binding
|
GO:0043393 |
60 |
0.093
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.092
|
|
|
|
embryonic skeletal system morphogenesis
|
GO:0048704 |
91 |
0.092
|
|
|
|
regulation of extent of cell growth
|
GO:0061387 |
52 |
0.091
|
Zebrafish |
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.090
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.090
|
Mouse Rat |
|
|
chromatin modification
|
GO:0016568 |
187 |
0.090
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.089
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.089
|
|
|
|
negative regulation of b cell proliferation
|
GO:0030889 |
13 |
0.088
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
42 |
0.087
|
|
|
|
negative chemotaxis
|
GO:0050919 |
14 |
0.087
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.086
|
|
|
|
negative regulation of dna replication
|
GO:0008156 |
4 |
0.086
|
|
|
|
kidney development
|
GO:0001822 |
213 |
0.086
|
|
|
|
response to alcohol
|
GO:0097305 |
48 |
0.086
|
|
|
|
response to monosaccharide
|
GO:0034284 |
67 |
0.085
|
|
|
|
protein acylation
|
GO:0043543 |
64 |
0.085
|
|
|
|
epithelium migration
|
GO:0090132 |
63 |
0.085
|
Zebrafish |
|
|
bone development
|
GO:0060348 |
120 |
0.085
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.085
|
Zebrafish Mouse |
|
|
dna methylation
|
GO:0006306 |
43 |
0.085
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.084
|
|
|
|
limb morphogenesis
|
GO:0035108 |
149 |
0.084
|
|
|
|
regulation of cell growth
|
GO:0001558 |
91 |
0.083
|
Zebrafish |
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.083
|
|
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
82 |
0.083
|
|
|
|
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090100 |
43 |
0.083
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.082
|
|
|
|
granulocyte migration
|
GO:0097530 |
43 |
0.082
|
Zebrafish Mouse |
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.082
|
Mouse |
|
|
dendrite development
|
GO:0016358 |
115 |
0.082
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
88 |
0.082
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.082
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.081
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.081
|
|
|
|
pallium development
|
GO:0021543 |
120 |
0.080
|
Mouse |
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.080
|
|
|
|
dna modification
|
GO:0006304 |
50 |
0.080
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.078
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.077
|
|
|
|
negative regulation of chemotaxis
|
GO:0050922 |
11 |
0.077
|
Zebrafish |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.077
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.076
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
74 |
0.076
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.076
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.076
|
Zebrafish |
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.075
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.075
|
Mouse |
|
|
nuclear division
|
GO:0000280 |
158 |
0.075
|
|
|
|
bone morphogenesis
|
GO:0060349 |
78 |
0.075
|
|
|
|
macrophage differentiation
|
GO:0030225 |
20 |
0.075
|
|
|
|
glial cell development
|
GO:0021782 |
54 |
0.075
|
|
|
|
membrane invagination
|
GO:0010324 |
17 |
0.074
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.074
|
Mouse |
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.074
|
Mouse Rat |
|
|
peptidyl lysine modification
|
GO:0018205 |
77 |
0.073
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
41 |
0.073
|
|
|
|
eye photoreceptor cell development
|
GO:0042462 |
31 |
0.073
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.072
|
Rat |
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.072
|
Zebrafish Mouse |
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
34 |
0.072
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.072
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.071
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.071
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.071
|
|
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
47 |
0.070
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
79 |
0.069
|
|
|
|
megakaryocyte differentiation
|
GO:0030219 |
26 |
0.069
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.069
|
Mouse |
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.068
|
Zebrafish Mouse |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.068
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.068
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.068
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.068
|
Mouse |
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.067
|
|
|
|
nephron development
|
GO:0072006 |
109 |
0.067
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.066
|
Zebrafish |
|
|
neurotransmitter secretion
|
GO:0007269 |
62 |
0.066
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.066
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
38 |
0.066
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.066
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.066
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.065
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.065
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.065
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.064
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.064
|
Mouse |
|
|
neuron migration
|
GO:0001764 |
122 |
0.064
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
139 |
0.064
|
Zebrafish |
|
|
body morphogenesis
|
GO:0010171 |
45 |
0.064
|
|
|
|
regulation of cardiac muscle tissue development
|
GO:0055024 |
31 |
0.064
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
50 |
0.064
|
Mouse |
|
|
kidney morphogenesis
|
GO:0060993 |
83 |
0.063
|
|
|
|
blood vessel remodeling
|
GO:0001974 |
33 |
0.063
|
|
|
|
peptide secretion
|
GO:0002790 |
114 |
0.063
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.063
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.063
|
|
|
|
mesonephric tubule morphogenesis
|
GO:0072171 |
63 |
0.063
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.063
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.063
|
|
|
|
hemostasis
|
GO:0007599 |
78 |
0.062
|
|
|
|
cellular glucose homeostasis
|
GO:0001678 |
52 |
0.062
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.062
|
Human Zebrafish Mouse Rat |
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
88 |
0.062
|
|
|
|
response to sterol
|
GO:0036314 |
4 |
0.061
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.061
|
|
|
|
histone acetylation
|
GO:0016573 |
41 |
0.061
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.060
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.060
|
|
|
|
insulin secretion
|
GO:0030073 |
89 |
0.060
|
|
|
|
glial cell apoptotic process
|
GO:0034349 |
3 |
0.059
|
|
|
|
regulation of erythrocyte differentiation
|
GO:0045646 |
23 |
0.059
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
82 |
0.059
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.059
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
35 |
0.058
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
44 |
0.058
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.058
|
Mouse |
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.058
|
|
|
|
mesonephric epithelium development
|
GO:0072163 |
94 |
0.058
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.058
|
Mouse |
|
|
negative regulation of response to wounding
|
GO:1903035 |
77 |
0.058
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
38 |
0.058
|
Zebrafish Mouse |
|
|
localization within membrane
|
GO:0051668 |
4 |
0.058
|
|
|
|
response to hypoxia
|
GO:0001666 |
58 |
0.058
|
Human |
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.057
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.057
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.057
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.057
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.057
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.057
|
|
|
|
nephron morphogenesis
|
GO:0072028 |
69 |
0.057
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.057
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.056
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.056
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.056
|
Zebrafish |
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.056
|
Mouse |
|
|
histone modification
|
GO:0016570 |
159 |
0.056
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.056
|
Mouse |
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
91 |
0.056
|
|
|
|
cell fate determination
|
GO:0001709 |
32 |
0.055
|
|
|
|
negative regulation of lipopolysaccharide mediated signaling pathway
|
GO:0031665 |
3 |
0.055
|
|
|
|
activation of rac gtpase activity
|
GO:0032863 |
2 |
0.054
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.054
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.054
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
64 |
0.053
|
|
|
|
neural crest cell development
|
GO:0014032 |
48 |
0.053
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.053
|
Mouse |
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.053
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.053
|
Zebrafish |
|
|
cardiac epithelial to mesenchymal transition
|
GO:0060317 |
18 |
0.053
|
|
|
|
release of cytochrome c from mitochondria
|
GO:0001836 |
23 |
0.053
|
|
|
|
tricuspid valve formation
|
GO:0003195 |
2 |
0.052
|
|
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.052
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.052
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
88 |
0.051
|
|
|
|
central nervous system neuron differentiation
|
GO:0021953 |
162 |
0.051
|
|
|
|
establishment of lymphocyte polarity
|
GO:0001767 |
2 |
0.050
|
|
|
|
regulation of peptide hormone secretion
|
GO:0090276 |
75 |
0.050
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.050
|
|
|
|
positive thymic t cell selection
|
GO:0045059 |
13 |
0.050
|
|
|
|
dendritic spine development
|
GO:0060996 |
30 |
0.050
|
|
|
|
regulation of dna methylation
|
GO:0044030 |
12 |
0.050
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
57 |
0.049
|
|
|
|
myeloid dendritic cell activation involved in immune response
|
GO:0002277 |
2 |
0.049
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
60 |
0.049
|
|
|
|
regulation of insulin secretion involved in cellular response to glucose stimulus
|
GO:0061178 |
31 |
0.049
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
95 |
0.049
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.049
|
|
|
|
neutrophil migration
|
GO:1990266 |
37 |
0.049
|
Zebrafish Mouse |
|
|
neural tube closure
|
GO:0001843 |
90 |
0.049
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.049
|
Mouse |
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.049
|
Mouse |
|
|
segmentation
|
GO:0035282 |
93 |
0.049
|
|
|
|
trophoblast giant cell differentiation
|
GO:0060707 |
15 |
0.049
|
|
|
|
chemokine mediated signaling pathway
|
GO:0070098 |
17 |
0.048
|
Mouse Rat |
|
|
regulation of neurotransmitter levels
|
GO:0001505 |
87 |
0.048
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.048
|
Mouse |
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.048
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.048
|
Mouse |
|
|
tube formation
|
GO:0035148 |
140 |
0.047
|
|
|
|
intestinal epithelial structure maintenance
|
GO:0060729 |
4 |
0.047
|
|
|
|
mesonephric tubule development
|
GO:0072164 |
94 |
0.047
|
|
|
|
activation of mapk activity involved in innate immune response
|
GO:0035419 |
2 |
0.047
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.046
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.046
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.046
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.046
|
|
