Mus musculus

170 known processes

Pkia

protein kinase inhibitor, alpha

(Aliases: AI415001,PKIalpha)

Pkia biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transmembrane transport GO:0055085 412 0.325
cation transport GO:0006812 399 0.197
synaptic transmission GO:0007268 329 0.175
regulation of cell projection organization GO:0031344 206 0.152
nitrogen compound transport GO:0071705 271 0.137
axonogenesis GO:0007409 274 0.135
regulation of neuron projection development GO:0010975 169 0.126
regulation of anatomical structure size GO:0090066 178 0.120
negative regulation of cell projection organization GO:0031345 56 0.117
regulation of neuron differentiation GO:0045664 281 0.114
protein catabolic process GO:0030163 221 0.105
regulation of membrane potential GO:0042391 192 0.100
neuron projection extension GO:1990138 64 0.091
cytoplasmic transport GO:0016482 234 0.091
positive regulation of cellular amine metabolic process GO:0033240 5 0.088
inorganic ion transmembrane transport GO:0098660 234 0.087
muscle cell differentiation GO:0042692 261 0.083
protein modification by small protein conjugation or removal GO:0070647 207 0.082
regulation of cell growth GO:0001558 91 0.080
ion transmembrane transport GO:0034220 361 0.077
regulation of cellular component size GO:0032535 121 0.077
regulation of voltage gated calcium channel activity GO:1901385 4 0.077
striated muscle tissue development GO:0014706 293 0.076
regulation of cellular catabolic process GO:0031329 242 0.072
cellular ketone metabolic process GO:0042180 84 0.071
neurotransmitter transport GO:0006836 76 0.070
positive regulation of programmed cell death GO:0043068 218 0.069
cell growth GO:0016049 130 0.068
negative regulation of cellular component organization GO:0051129 194 0.068
organelle localization GO:0051640 179 0.067
regulation of nucleotide catabolic process GO:0030811 122 0.066
regulation of protein localization GO:0032880 231 0.065
muscle cell development GO:0055001 133 0.065
regulation of neurotransmitter levels GO:0001505 87 0.065
regulation of ion transport GO:0043269 215 0.065
multicellular organismal signaling GO:0035637 91 0.065
olfactory learning GO:0008355 2 0.064
organonitrogen compound catabolic process GO:1901565 264 0.063
cellular amino acid metabolic process GO:0006520 103 0.062
regulation of secretion by cell GO:1903530 249 0.062
intracellular protein transport GO:0006886 204 0.061
regulation of organelle organization GO:0033043 289 0.059
regulation of cellular ketone metabolic process GO:0010565 66 0.058
protein ubiquitination GO:0016567 171 0.057
regulation of system process GO:0044057 200 0.055
negative regulation of neuron differentiation GO:0045665 101 0.053
regulation of cellular amino acid metabolic process GO:0006521 5 0.053
cellular protein complex assembly GO:0043623 116 0.053
actin cytoskeleton organization GO:0030036 220 0.053
nucleoside phosphate metabolic process GO:0006753 338 0.052
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.051
stem cell differentiation GO:0048863 268 0.050
developmental cell growth GO:0048588 84 0.049
muscle tissue development GO:0060537 308 0.047
regulation of kinase activity GO:0043549 249 0.047
purine nucleoside triphosphate metabolic process GO:0009144 226 0.047
synapse organization GO:0050808 125 0.047
cellular amine metabolic process GO:0044106 44 0.047
developmental growth involved in morphogenesis GO:0060560 138 0.046
regulation of apoptotic signaling pathway GO:2001233 197 0.046
epithelial tube morphogenesis GO:0060562 303 0.046
striated muscle cell development GO:0055002 125 0.045
gland development GO:0048732 330 0.045
camera type eye development GO:0043010 266 0.045
dendrite development GO:0016358 115 0.045
regulation of cell size GO:0008361 72 0.045
organelle assembly GO:0070925 177 0.044
regulation of transmembrane transport GO:0034762 128 0.044
dendritic spine development GO:0060996 30 0.044
negative regulation of cell growth GO:0030308 44 0.043
positive regulation of apoptotic signaling pathway GO:2001235 95 0.043
regulation of actin cytoskeleton organization GO:0032956 84 0.043
axon guidance GO:0007411 141 0.043
regulation of axon extension GO:0030516 43 0.042
regulation of secretion GO:0051046 274 0.041
positive regulation of neuron differentiation GO:0045666 141 0.041
heart morphogenesis GO:0003007 178 0.040
cellular response to organonitrogen compound GO:0071417 145 0.040
endomembrane system organization GO:0010256 147 0.040
regulation of dendritic spine development GO:0060998 22 0.040
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.039
mitochondrion transport along microtubule GO:0047497 3 0.039
macromolecule catabolic process GO:0009057 281 0.039
positive regulation of protein modification process GO:0031401 299 0.038
regulation of neurotransmitter transport GO:0051588 35 0.038
positive regulation of neuron projection development GO:0010976 79 0.038
cellular ion homeostasis GO:0006873 165 0.038
regulation of hydrolase activity GO:0051336 246 0.038
response to organonitrogen compound GO:0010243 246 0.037
regulation of actin filament based process GO:0032970 99 0.037
cellular lipid metabolic process GO:0044255 323 0.037
microtubule polymerization or depolymerization GO:0031109 26 0.037
positive regulation of cell death GO:0010942 224 0.037
protein localization to membrane GO:0072657 108 0.037
ventral trunk neural crest cell migration GO:0036486 4 0.036
establishment of organelle localization GO:0051656 122 0.036
regulation of cellular component biogenesis GO:0044087 181 0.036
ribose phosphate metabolic process GO:0019693 291 0.036
negative regulation of neuron projection development GO:0010977 50 0.036
telencephalon development GO:0021537 186 0.036
nucleotide metabolic process GO:0009117 332 0.035
neuronal action potential GO:0019228 54 0.035
associative learning GO:0008306 61 0.035
cellular potassium ion transport GO:0071804 43 0.034
morphogenesis of a branching structure GO:0001763 203 0.034
chemotaxis GO:0006935 247 0.034
lipid biosynthetic process GO:0008610 179 0.034
lipid localization GO:0010876 126 0.034
positive regulation of apoptotic process GO:0043065 217 0.034
sympathetic neuron projection extension GO:0097490 4 0.033
positive regulation of dendritic spine development GO:0060999 12 0.033
regulation of phosphatidylcholine catabolic process GO:0010899 2 0.033
positive regulation of nervous system development GO:0051962 221 0.033
negative regulation of cell proliferation GO:0008285 296 0.033
negative regulation of cell development GO:0010721 169 0.033
positive regulation of cell projection organization GO:0031346 95 0.033
nucleoside metabolic process GO:0009116 246 0.033
asymmetric neuroblast division GO:0055059 1 0.033
regulation of vasculature development GO:1901342 88 0.033
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.032
oxidation reduction process GO:0055114 342 0.032
regulation of cytoskeleton organization GO:0051493 122 0.032
regulation of intracellular transport GO:0032386 159 0.032
negative regulation of nervous system development GO:0051961 156 0.032
inorganic cation transmembrane transport GO:0098662 207 0.032
nucleotide catabolic process GO:0009166 217 0.031
sequestering of calcium ion GO:0051208 18 0.031
morphogenesis of embryonic epithelium GO:0016331 159 0.031
nucleobase containing small molecule metabolic process GO:0055086 352 0.031
neuron projection guidance GO:0097485 141 0.031
ribonucleotide metabolic process GO:0009259 291 0.031
cell cell signaling involved in lung development GO:0060495 1 0.031
regulation of ion transmembrane transport GO:0034765 119 0.030
positive regulation of high voltage gated calcium channel activity GO:1901843 1 0.030
regulation of high voltage gated calcium channel activity GO:1901841 2 0.030
ribonucleoside triphosphate metabolic process GO:0009199 220 0.030
heterocycle catabolic process GO:0046700 280 0.030
nucleoside phosphate catabolic process GO:1901292 222 0.030
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.030
glycosyl compound metabolic process GO:1901657 246 0.029
protein polymerization GO:0051258 57 0.029
purine ribonucleoside metabolic process GO:0046128 241 0.029
angiogenesis GO:0001525 201 0.029
male gamete generation GO:0048232 285 0.029
regulation of neuron apoptotic process GO:0043523 122 0.029
fatty acid biosynthetic process GO:0006633 41 0.029
cell type specific apoptotic process GO:0097285 268 0.029
cellular component assembly involved in morphogenesis GO:0010927 139 0.029
epithelium migration GO:0090132 63 0.028
mapk cascade GO:0000165 281 0.028
blood vessel morphogenesis GO:0048514 285 0.028
purine nucleotide metabolic process GO:0006163 302 0.028
response to growth factor GO:0070848 198 0.028
cognition GO:0050890 149 0.028
nucleoside catabolic process GO:0009164 206 0.028
membrane depolarization GO:0051899 64 0.027
cation transmembrane transport GO:0098655 266 0.027
neuron apoptotic process GO:0051402 142 0.027
aromatic compound catabolic process GO:0019439 286 0.027
purine nucleotide catabolic process GO:0006195 211 0.027
inter male aggressive behavior GO:0002121 3 0.027
transmission of nerve impulse GO:0019226 76 0.027
apoptotic signaling pathway GO:0097190 306 0.026
action potential GO:0001508 78 0.026
tube formation GO:0035148 140 0.026
protein localization to organelle GO:0033365 185 0.026
cellular response to lipopolysaccharide GO:0071222 77 0.026
organophosphate catabolic process GO:0046434 232 0.026
ameboidal type cell migration GO:0001667 128 0.026
striated muscle myosin thick filament assembly GO:0071688 1 0.026
response to host GO:0075136 3 0.026
ribonucleoside metabolic process GO:0009119 245 0.026
calcium ion transport GO:0006816 159 0.026
myosin filament organization GO:0031033 3 0.025
nucleoside triphosphate metabolic process GO:0009141 230 0.025
negative regulation of cytoskeleton organization GO:0051494 36 0.025
white fat cell proliferation GO:0070343 2 0.025
muscle fiber development GO:0048747 76 0.025
energy derivation by oxidation of organic compounds GO:0015980 77 0.025
positive regulation of white fat cell proliferation GO:0070352 1 0.025
neural tube development GO:0021915 160 0.025
cellular homeostasis GO:0019725 240 0.024
monocarboxylic acid metabolic process GO:0032787 191 0.024
regulation of purine nucleotide metabolic process GO:1900542 169 0.024
small gtpase mediated signal transduction GO:0007264 97 0.024
regulation of neurotransmitter secretion GO:0046928 29 0.024
forebrain cell migration GO:0021885 58 0.024
response to lipopolysaccharide GO:0032496 128 0.024
muscle contraction GO:0006936 101 0.024
bone development GO:0060348 120 0.024
regulation of cellular amine metabolic process GO:0033238 20 0.024
atp metabolic process GO:0046034 75 0.024
neuron migration GO:0001764 122 0.024
negative regulation of organelle organization GO:0010639 90 0.024
ribonucleoside catabolic process GO:0042454 206 0.024
negative regulation of growth GO:0045926 99 0.023
regulation of ion transmembrane transporter activity GO:0032412 54 0.023
regulation of protein depolymerization GO:1901879 26 0.023
regulation of mapk cascade GO:0043408 248 0.023
wnt signaling pathway GO:0016055 188 0.023
metal ion homeostasis GO:0055065 189 0.023
organic hydroxy compound transport GO:0015850 93 0.023
maintenance of location GO:0051235 89 0.023
ribonucleoside monophosphate catabolic process GO:0009158 57 0.023
immune effector process GO:0002252 321 0.023
generation of precursor metabolites and energy GO:0006091 103 0.023
regulation of cell motility GO:2000145 236 0.022
neurotransmitter secretion GO:0007269 62 0.022
organ growth GO:0035265 117 0.022
protein modification by small protein conjugation GO:0032446 187 0.022
glial cell differentiation GO:0010001 131 0.022
ras protein signal transduction GO:0007265 77 0.022
learning or memory GO:0007611 148 0.022
regulation of epithelial cell proliferation GO:0050678 141 0.022
epithelial cell migration GO:0010631 63 0.022
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.022
ribonucleoside monophosphate metabolic process GO:0009161 80 0.022
purine containing compound metabolic process GO:0072521 311 0.022
purine nucleoside metabolic process GO:0042278 241 0.022
stem cell development GO:0048864 219 0.022
positive regulation of dendrite development GO:1900006 21 0.022
sterol transmembrane transport GO:0035382 2 0.021
regulation of cell cycle GO:0051726 281 0.021
anion transport GO:0006820 177 0.021
response to extracellular stimulus GO:0009991 127 0.021
ribonucleoside triphosphate catabolic process GO:0009203 199 0.021
purine ribonucleotide catabolic process GO:0009154 208 0.021
regulation of angiogenesis GO:0045765 81 0.021
positive regulation of dendritic spine morphogenesis GO:0061003 8 0.021
cation homeostasis GO:0055080 212 0.021
hematopoietic progenitor cell differentiation GO:0002244 143 0.021
ribonucleotide catabolic process GO:0009261 208 0.021
forebrain development GO:0030900 302 0.021
hippocampus development GO:0021766 52 0.021
purine nucleoside catabolic process GO:0006152 205 0.021
multicellular organism growth GO:0035264 161 0.021
mitochondrion organization GO:0007005 134 0.021
positive regulation of secretion by cell GO:1903532 114 0.021
cellular metal ion homeostasis GO:0006875 151 0.020
skeletal muscle organ development GO:0060538 163 0.020
response to molecule of bacterial origin GO:0002237 143 0.020
sarcomere organization GO:0045214 24 0.020
establishment of mitochondrion localization GO:0051654 4 0.020
nuclear transport GO:0051169 139 0.020
regulation of cytoplasmic transport GO:1903649 112 0.020
leukocyte proliferation GO:0070661 172 0.020
cell adhesion GO:0007155 329 0.020
dna metabolic process GO:0006259 303 0.020
pallium development GO:0021543 120 0.020
compound eye development GO:0048749 1 0.020
fatty acid metabolic process GO:0006631 121 0.020
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.020
peptidyl amino acid modification GO:0018193 336 0.020
i kappab kinase nf kappab signaling GO:0007249 85 0.019
peptide transport GO:0015833 133 0.019
positive regulation of atpase activity GO:0032781 3 0.019
sequestering of metal ion GO:0051238 19 0.019
regulation of protein kinase activity GO:0045859 232 0.019
glycerolipid metabolic process GO:0046486 122 0.019
cellular chemical homeostasis GO:0055082 215 0.019
purine ribonucleotide metabolic process GO:0009150 290 0.019
negative regulation of microtubule polymerization or depolymerization GO:0031111 15 0.019
purine ribonucleoside catabolic process GO:0046130 205 0.019
regulation of protein complex disassembly GO:0043244 28 0.019
amide transport GO:0042886 138 0.019
regulation of purine nucleotide catabolic process GO:0033121 122 0.019
mitotic cell cycle process GO:1903047 159 0.019
positive regulation of secretion GO:0051047 130 0.019
carboxylic acid transport GO:0046942 100 0.019
mitotic cell cycle GO:0000278 195 0.019
regulation of homeostatic process GO:0032844 182 0.019
regulation of cell activation GO:0050865 289 0.019
myosin filament assembly GO:0031034 2 0.019
neuron death GO:0070997 154 0.019
positive regulation of ion transport GO:0043270 65 0.019
calcium ion transmembrane transport GO:0070588 85 0.019
sensory perception of mechanical stimulus GO:0050954 107 0.019
regulation of ion homeostasis GO:2000021 64 0.019
regulation of cell migration GO:0030334 219 0.018
regulation of neuron death GO:1901214 134 0.018
positive regulation of transferase activity GO:0051347 167 0.018
response to organic cyclic compound GO:0014070 198 0.018
embryonic epithelial tube formation GO:0001838 130 0.018
carbohydrate metabolic process GO:0005975 230 0.018
posttranscriptional regulation of gene expression GO:0010608 155 0.018
heart contraction GO:0060047 93 0.018
protein localization to plasma membrane GO:0072659 57 0.018
necrotic cell death GO:0070265 30 0.018
organic anion transport GO:0015711 137 0.018
regulation of extent of cell growth GO:0061387 52 0.018
purine containing compound catabolic process GO:0072523 213 0.018
positive regulation of cell development GO:0010720 237 0.018
salivary gland morphogenesis GO:0007435 33 0.018
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.018
mitochondrion distribution GO:0048311 4 0.018
regulation of cell projection assembly GO:0060491 38 0.018
regulation of transferase activity GO:0051338 263 0.018
microtubule based process GO:0007017 236 0.018
respiratory tube development GO:0030323 167 0.018
sympathetic neuron projection guidance GO:0097491 4 0.018
cellular calcium ion homeostasis GO:0006874 119 0.018
purine nucleoside monophosphate metabolic process GO:0009126 81 0.018
mesenchyme development GO:0060485 152 0.018
protein targeting GO:0006605 143 0.018
regulation of microtubule based process GO:0032886 52 0.018
cerebral cortex radially oriented cell migration GO:0021799 31 0.018
nucleoside monophosphate metabolic process GO:0009123 85 0.018
carboxylic acid biosynthetic process GO:0046394 86 0.017
actomyosin structure organization GO:0031032 56 0.017
regulation of protein transport GO:0051223 163 0.017
atp catabolic process GO:0006200 55 0.017
epithelial cell proliferation GO:0050673 174 0.017
cellular response to lipid GO:0071396 145 0.017
negative regulation of molecular function GO:0044092 258 0.017
response to transforming growth factor beta GO:0071559 88 0.017
oligodendrocyte differentiation GO:0048709 53 0.017
positive regulation of nucleotide metabolic process GO:0045981 114 0.017
cellular glucan metabolic process GO:0006073 32 0.017
cartilage development GO:0051216 140 0.016
regulation of postsynaptic membrane potential GO:0060078 48 0.016
cellular carbohydrate metabolic process GO:0044262 119 0.016
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.016
establishment of protein localization to organelle GO:0072594 118 0.016
organic cyclic compound catabolic process GO:1901361 295 0.016
protein import into nucleus GO:0006606 95 0.016
membrane organization GO:0061024 245 0.016
positive regulation of cellular component biogenesis GO:0044089 94 0.016
carbohydrate transport GO:0008643 62 0.016
sa node cell action potential GO:0086015 4 0.016
rho protein signal transduction GO:0007266 32 0.016
plasma membrane organization GO:0007009 90 0.016
regulation of white fat cell proliferation GO:0070350 2 0.016
organonitrogen compound biosynthetic process GO:1901566 192 0.016
potassium ion transport GO:0006813 52 0.016
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.016
positive regulation of mapk cascade GO:0043410 170 0.016
reactive oxygen species metabolic process GO:0072593 84 0.016
glycosyl compound catabolic process GO:1901658 206 0.016
response to inorganic substance GO:0010035 96 0.016
appendage development GO:0048736 166 0.016
sodium ion transport GO:0006814 73 0.016
cardiac muscle cell development GO:0055013 39 0.015
regulation of nucleotide metabolic process GO:0006140 169 0.015
regulation of establishment of protein localization GO:0070201 181 0.015
cellular macromolecule catabolic process GO:0044265 206 0.015
carbohydrate derivative biosynthetic process GO:1901137 183 0.015
regulation of morphogenesis of a branching structure GO:0060688 53 0.015
neuron neuron synaptic transmission GO:0007270 69 0.015
macromolecular complex disassembly GO:0032984 43 0.015
spermatogenesis GO:0007283 284 0.015
guanosine containing compound metabolic process GO:1901068 144 0.015
male genitalia morphogenesis GO:0048808 4 0.015
protein complex disassembly GO:0043241 40 0.015
trunk segmentation GO:0035290 4 0.015
negative regulation of phosphorylation GO:0042326 166 0.015
relaxation of vascular smooth muscle GO:0060087 7 0.015
homeostasis of number of cells GO:0048872 210 0.015
regulation of atp metabolic process GO:1903578 17 0.015
fat cell proliferation GO:0070341 4 0.015
acetylcholine transport GO:0015870 2 0.015
cerebral cortex radial glia guided migration GO:0021801 17 0.015
potassium ion transmembrane transport GO:0071805 43 0.015
protein kinase b signaling GO:0043491 74 0.015
cellular response to organic cyclic compound GO:0071407 87 0.015
establishment or maintenance of neuroblast polarity GO:0045196 1 0.015
actin filament based movement GO:0030048 23 0.015
cellular response to molecule of bacterial origin GO:0071219 83 0.015
response to immune response of other organism involved in symbiotic interaction GO:0052564 3 0.015
regulation of b cell activation GO:0050864 81 0.015
myeloid leukocyte differentiation GO:0002573 119 0.015
monocarboxylic acid biosynthetic process GO:0072330 61 0.015
cardiac muscle tissue development GO:0048738 130 0.015
organic hydroxy compound metabolic process GO:1901615 203 0.015
regulation of proteolysis GO:0030162 164 0.015
cellular response to acid chemical GO:0071229 68 0.014
organic acid biosynthetic process GO:0016053 86 0.014
serotonin uptake GO:0051610 3 0.014
regulation of heart contraction GO:0008016 77 0.014
response to light stimulus GO:0009416 135 0.014
vacuole organization GO:0007033 38 0.014
dorsal ventral axon guidance GO:0033563 3 0.014
cytokinetic process GO:0032506 2 0.014
positive regulation of protein phosphorylation GO:0001934 242 0.014
regulation of intracellular protein transport GO:0033157 82 0.014
negative regulation of serotonin uptake GO:0051612 2 0.014
positive regulation of cell migration GO:0030335 109 0.014
positive regulation of potassium ion transport GO:0043268 3 0.014
regulation of glucose transport GO:0010827 32 0.014
nucleoside monophosphate catabolic process GO:0009125 59 0.014
metencephalon development GO:0022037 89 0.014
establishment or maintenance of cell polarity GO:0007163 86 0.014
regulation of mitotic cell cycle GO:0007346 126 0.014
blood circulation GO:0008015 195 0.014
acetate ester transport GO:1901374 2 0.014
locomotory behavior GO:0007626 195 0.014
cerebral cortex cell migration GO:0021795 44 0.014
negative regulation of protein metabolic process GO:0051248 282 0.014
regulation of peptide transport GO:0090087 91 0.014
regulation of hormone levels GO:0010817 211 0.014
exocytosis GO:0006887 121 0.014
sensory perception GO:0007600 245 0.014
regionalization GO:0003002 337 0.014
multi multicellular organism process GO:0044706 109 0.014
peptide hormone secretion GO:0030072 109 0.014
cellular response to biotic stimulus GO:0071216 92 0.014
positive regulation of sodium ion transport GO:0010765 13 0.014
regulation of nucleoside metabolic process GO:0009118 130 0.014
syncytium formation by plasma membrane fusion GO:0000768 42 0.014
nucleocytoplasmic transport GO:0006913 139 0.014
lymphocyte homeostasis GO:0002260 64 0.014
negative regulation of immune system process GO:0002683 209 0.014
regulation of cell cycle process GO:0010564 160 0.014
cerebellum morphogenesis GO:0021587 42 0.014
exocrine system development GO:0035272 45 0.014
inflammatory response GO:0006954 244 0.014
semicircular canal fusion GO:0060879 1 0.014
skeletal system development GO:0001501 356 0.014
gtp metabolic process GO:0046039 144 0.014
divalent inorganic cation transport GO:0072511 178 0.013
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.013
multicellular organismal response to stress GO:0033555 62 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.013
adult behavior GO:0030534 135 0.013
amino acid transport GO:0006865 61 0.013
response to amino acid GO:0043200 37 0.013
carbohydrate derivative catabolic process GO:1901136 231 0.013
regulation of transporter activity GO:0032409 57 0.013
regulation of protein localization to nucleus GO:1900180 60 0.013
mesenchymal epithelial cell signaling involved in lung development GO:0060496 1 0.013
regulation of protein serine threonine kinase activity GO:0071900 157 0.013
asymmetric stem cell division GO:0098722 3 0.013
cardiac muscle cell differentiation GO:0055007 69 0.013
negative regulation of apoptotic signaling pathway GO:2001234 104 0.013
regulation of synaptic plasticity GO:0048167 87 0.013
peptidyl serine modification GO:0018209 83 0.013
positive regulation of leukocyte proliferation GO:0070665 73 0.013
defense response to bacterium GO:0042742 119 0.013
defense response to other organism GO:0098542 197 0.013
positive regulation of dna templated transcription elongation GO:0032786 2 0.013
rhodopsin mediated signaling pathway GO:0016056 4 0.013
reactive nitrogen species metabolic process GO:2001057 0 0.013
establishment of vesicle localization GO:0051650 81 0.013
regulation of sarcomere organization GO:0060297 4 0.013
substantia nigra development GO:0021762 2 0.013
cell division GO:0051301 120 0.013
regulation of lipid metabolic process GO:0019216 118 0.013
purine nucleoside monophosphate catabolic process GO:0009128 58 0.013
stem cell proliferation GO:0072089 117 0.013
regulation of cation channel activity GO:2001257 22 0.013
mrna splicing via spliceosome GO:0000398 43 0.013
response to oxidative stress GO:0006979 123 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.013
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.013
regulation of protein complex assembly GO:0043254 83 0.013
retina development in camera type eye GO:0060041 119 0.013
regulation of nucleocytoplasmic transport GO:0046822 73 0.013
mesenchymal cell differentiation GO:0048762 107 0.012
relaxation of muscle GO:0090075 18 0.012
negative regulation of mitotic cell cycle GO:0045930 58 0.012
glucose transport GO:0015758 56 0.012
myelination GO:0042552 74 0.012
bone morphogenesis GO:0060349 78 0.012
harderian gland development GO:0070384 2 0.012
carbohydrate homeostasis GO:0033500 128 0.012
male anatomical structure morphogenesis GO:0090598 4 0.012
circulatory system process GO:0003013 197 0.012
divalent metal ion transport GO:0070838 172 0.012
nucleoside triphosphate catabolic process GO:0009143 205 0.012
response to acid chemical GO:0001101 111 0.012
cellular response to abiotic stimulus GO:0071214 56 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.012
cardiac cell development GO:0055006 41 0.012
positive regulation of protein kinase activity GO:0045860 144 0.012
female genitalia morphogenesis GO:0048807 3 0.012

Pkia disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
muscular disease DOID:0080000 0 0.134
disease of anatomical entity DOID:7 0 0.134
musculoskeletal system disease DOID:17 0 0.134
myopathy DOID:423 0 0.111
muscle tissue disease DOID:66 0 0.111
nervous system disease DOID:863 0 0.088
central nervous system disease DOID:331 0 0.035
muscular dystrophy DOID:9884 0 0.028
cardiovascular system disease DOID:1287 0 0.019
heart disease DOID:114 0 0.019
cardiomyopathy DOID:0050700 0 0.019
disease of mental health DOID:150 0 0.016
non syndromic intellectual disability DOID:0050889 0 0.016
developmental disorder of mental health DOID:0060037 0 0.016
specific developmental disorder DOID:0060038 0 0.016
intellectual disability DOID:1059 0 0.016
intrinsic cardiomyopathy DOID:0060036 0 0.015
sensory system disease DOID:0050155 0 0.014
eye and adnexa disease DOID:1492 0 0.014
brain disease DOID:936 0 0.013
neurodegenerative disease DOID:1289 0 0.012