Mus musculus

43 known processes

Gss

glutathione synthetase

(Aliases: GS-A/GS-B,AI314904)

Gss biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 103 0.110
transmembrane transport GO:0055085 412 0.084
cation transport GO:0006812 399 0.057
ion transmembrane transport GO:0034220 361 0.056
cellular ketone metabolic process GO:0042180 84 0.054
oxidation reduction process GO:0055114 342 0.050
regulation of cellular ketone metabolic process GO:0010565 66 0.047
cellular lipid metabolic process GO:0044255 323 0.046
amine metabolic process GO:0009308 45 0.044
cellular amine metabolic process GO:0044106 44 0.041
nucleotide metabolic process GO:0009117 332 0.039
regulation of cellular amino acid metabolic process GO:0006521 5 0.039
regulation of cellular amine metabolic process GO:0033238 20 0.039
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.038
anion transport GO:0006820 177 0.037
organic cyclic compound catabolic process GO:1901361 295 0.035
nucleobase containing small molecule metabolic process GO:0055086 352 0.034
apoptotic signaling pathway GO:0097190 306 0.034
nucleoside phosphate metabolic process GO:0006753 338 0.032
male gamete generation GO:0048232 285 0.032
sulfur compound metabolic process GO:0006790 100 0.032
cation transmembrane transport GO:0098655 266 0.032
protein maturation GO:0051604 176 0.031
purine ribonucleoside metabolic process GO:0046128 241 0.031
cellular nitrogen compound catabolic process GO:0044270 280 0.031
membrane organization GO:0061024 245 0.030
positive regulation of cellular amine metabolic process GO:0033240 5 0.030
response to organic cyclic compound GO:0014070 198 0.029
monocarboxylic acid metabolic process GO:0032787 191 0.029
organic anion transport GO:0015711 137 0.029
nitrogen compound transport GO:0071705 271 0.029
purine nucleoside metabolic process GO:0042278 241 0.029
intracellular protein transport GO:0006886 204 0.029
aromatic compound catabolic process GO:0019439 286 0.029
purine containing compound metabolic process GO:0072521 311 0.028
glycosyl compound metabolic process GO:1901657 246 0.028
negative regulation of molecular function GO:0044092 258 0.028
regulation of organelle organization GO:0033043 289 0.027
inflammatory response GO:0006954 244 0.027
carbohydrate metabolic process GO:0005975 230 0.027
carbohydrate derivative catabolic process GO:1901136 231 0.027
organic hydroxy compound metabolic process GO:1901615 203 0.027
organic acid transport GO:0015849 101 0.027
inorganic cation transmembrane transport GO:0098662 207 0.027
carboxylic acid transport GO:0046942 100 0.026
cation homeostasis GO:0055080 212 0.026
mapk cascade GO:0000165 281 0.026
nucleoside metabolic process GO:0009116 246 0.026
cell adhesion GO:0007155 329 0.025
spermatogenesis GO:0007283 284 0.025
purine nucleotide metabolic process GO:0006163 302 0.025
regulation of membrane potential GO:0042391 192 0.025
regulation of protein localization GO:0032880 231 0.024
regulation of mapk cascade GO:0043408 248 0.024
cellular homeostasis GO:0019725 240 0.024
negative regulation of cellular protein metabolic process GO:0032269 247 0.024
cytoplasmic transport GO:0016482 234 0.024
nucleoside phosphate catabolic process GO:1901292 222 0.024
regulation of transferase activity GO:0051338 263 0.024
cellular response to cytokine stimulus GO:0071345 189 0.024
organonitrogen compound catabolic process GO:1901565 264 0.023
regulation of kinase activity GO:0043549 249 0.023
sensory perception GO:0007600 245 0.023
negative regulation of protein metabolic process GO:0051248 282 0.023
positive regulation of cell death GO:0010942 224 0.023
regulation of apoptotic signaling pathway GO:2001233 197 0.023
ribonucleoside metabolic process GO:0009119 245 0.023
ribose phosphate metabolic process GO:0019693 291 0.023
heterocycle catabolic process GO:0046700 280 0.023
inorganic ion transmembrane transport GO:0098660 234 0.023
purine nucleoside catabolic process GO:0006152 205 0.023
carbohydrate derivative biosynthetic process GO:1901137 183 0.023
regulation of cell activation GO:0050865 289 0.023
purine ribonucleoside catabolic process GO:0046130 205 0.023
purine nucleoside triphosphate metabolic process GO:0009144 226 0.023
striated muscle tissue development GO:0014706 293 0.022
ribonucleotide metabolic process GO:0009259 291 0.022
endomembrane system organization GO:0010256 147 0.022
positive regulation of protein modification process GO:0031401 299 0.022
nucleotide catabolic process GO:0009166 217 0.022
cellular chemical homeostasis GO:0055082 215 0.022
cellular ion homeostasis GO:0006873 165 0.022
reactive oxygen species metabolic process GO:0072593 84 0.022
positive regulation of programmed cell death GO:0043068 218 0.021
regulation of hydrolase activity GO:0051336 246 0.021
small gtpase mediated signal transduction GO:0007264 97 0.021
protein targeting GO:0006605 143 0.021
response to organonitrogen compound GO:0010243 246 0.021
glycosyl compound catabolic process GO:1901658 206 0.021
macromolecule catabolic process GO:0009057 281 0.021
leukocyte proliferation GO:0070661 172 0.021
protein processing GO:0016485 163 0.021
regulation of hormone levels GO:0010817 211 0.020
muscle tissue development GO:0060537 308 0.020
regulation of cytokine production GO:0001817 266 0.020
ras protein signal transduction GO:0007265 77 0.020
regulation of ion transport GO:0043269 215 0.020
organic acid biosynthetic process GO:0016053 86 0.020
purine nucleotide catabolic process GO:0006195 211 0.020
ribonucleoside triphosphate metabolic process GO:0009199 220 0.020
immune effector process GO:0002252 321 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.020
nucleoside catabolic process GO:0009164 206 0.020
blood circulation GO:0008015 195 0.020
ribonucleoside catabolic process GO:0042454 206 0.020
regulation of protein serine threonine kinase activity GO:0071900 157 0.020
dna metabolic process GO:0006259 303 0.020
leukocyte differentiation GO:0002521 342 0.020
divalent inorganic cation transport GO:0072511 178 0.020
positive regulation of apoptotic process GO:0043065 217 0.019
microtubule based process GO:0007017 236 0.019
fatty acid metabolic process GO:0006631 121 0.019
alpha amino acid metabolic process GO:1901605 59 0.019
regulation of defense response GO:0031347 233 0.019
cytokine production GO:0001816 319 0.019
protein localization to organelle GO:0033365 185 0.019
regulation of lymphocyte activation GO:0051249 240 0.019
ribonucleotide catabolic process GO:0009261 208 0.019
nucleoside triphosphate metabolic process GO:0009141 230 0.019
cell type specific apoptotic process GO:0097285 268 0.019
cellular amide metabolic process GO:0043603 58 0.019
regulation of secretion GO:0051046 274 0.018
circulatory system process GO:0003013 197 0.018
protein catabolic process GO:0030163 221 0.018
posttranscriptional regulation of gene expression GO:0010608 155 0.018
compound eye development GO:0048749 1 0.018
purine ribonucleotide metabolic process GO:0009150 290 0.018
regulation of anatomical structure size GO:0090066 178 0.018
xenobiotic catabolic process GO:0042178 1 0.018
peptidyl amino acid modification GO:0018193 336 0.018
purine ribonucleotide catabolic process GO:0009154 208 0.018
response to inorganic substance GO:0010035 96 0.018
skin development GO:0043588 220 0.018
neuronal action potential GO:0019228 54 0.018
purine containing compound catabolic process GO:0072523 213 0.018
organonitrogen compound biosynthetic process GO:1901566 192 0.018
regulation of establishment of protein localization GO:0070201 181 0.018
purine nucleoside triphosphate catabolic process GO:0009146 203 0.018
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.018
small molecule biosynthetic process GO:0044283 132 0.018
multicellular organismal signaling GO:0035637 91 0.018
ribonucleoside triphosphate catabolic process GO:0009203 199 0.018
homeostasis of number of cells GO:0048872 210 0.018
myeloid cell differentiation GO:0030099 233 0.018
regulation of cell cycle GO:0051726 281 0.017
cellular modified amino acid metabolic process GO:0006575 63 0.017
germ cell development GO:0007281 185 0.017
response to molecule of bacterial origin GO:0002237 143 0.017
negative regulation of cell proliferation GO:0008285 296 0.017
positive regulation of protein phosphorylation GO:0001934 242 0.017
transmission of nerve impulse GO:0019226 76 0.017
dephosphorylation GO:0016311 129 0.017
leukocyte mediated immunity GO:0002443 174 0.017
positive regulation of hydrolase activity GO:0051345 148 0.017
cellular response to lipid GO:0071396 145 0.017
t cell activation GO:0042110 289 0.017
response to oxidative stress GO:0006979 123 0.017
sensory organ morphogenesis GO:0090596 242 0.017
carboxylic acid biosynthetic process GO:0046394 86 0.017
divalent metal ion transport GO:0070838 172 0.017
negative regulation of phosphorus metabolic process GO:0010563 184 0.017
regulation of homeostatic process GO:0032844 182 0.017
negative regulation of cellular amine metabolic process GO:0033239 1 0.017
muscle cell differentiation GO:0042692 261 0.016
cellular metal ion homeostasis GO:0006875 151 0.016
regulation of reactive oxygen species metabolic process GO:2000377 40 0.016
organophosphate catabolic process GO:0046434 232 0.016
metal ion homeostasis GO:0055065 189 0.016
plasma membrane organization GO:0007009 90 0.016
blood vessel morphogenesis GO:0048514 285 0.016
lymphocyte proliferation GO:0046651 164 0.016
glutathione metabolic process GO:0006749 16 0.016
protein localization to membrane GO:0072657 108 0.016
response to lipopolysaccharide GO:0032496 128 0.016
cellular macromolecule catabolic process GO:0044265 206 0.016
regulation of response to wounding GO:1903034 189 0.016
spermatid development GO:0007286 108 0.016
lateral inhibition GO:0046331 1 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.016
synaptic transmission GO:0007268 329 0.016
actin cytoskeleton organization GO:0030036 220 0.015
regulation of neuron differentiation GO:0045664 281 0.015
regulation of cellular catabolic process GO:0031329 242 0.015
negative regulation of cellular component organization GO:0051129 194 0.015
negative regulation of immune system process GO:0002683 209 0.015
nuclear transport GO:0051169 139 0.015
extrinsic apoptotic signaling pathway GO:0097191 126 0.015
rho protein signal transduction GO:0007266 32 0.015
establishment of protein localization to organelle GO:0072594 118 0.015
nucleoside triphosphate catabolic process GO:0009143 205 0.015
sphingolipid metabolic process GO:0006665 45 0.015
regulation of cellular response to stress GO:0080135 159 0.015
cellular amino acid biosynthetic process GO:0008652 22 0.015
multicellular organismal homeostasis GO:0048871 164 0.015
lipid biosynthetic process GO:0008610 179 0.015
cell substrate adhesion GO:0031589 130 0.015
forebrain development GO:0030900 302 0.015
regulation of protein kinase activity GO:0045859 232 0.015
g protein coupled receptor signaling pathway GO:0007186 243 0.015
negative regulation of phosphate metabolic process GO:0045936 184 0.014
positive regulation of protein kinase activity GO:0045860 144 0.014
maintenance of location GO:0051235 89 0.014
camera type eye development GO:0043010 266 0.014
regulation of cell cycle process GO:0010564 160 0.014
regulation of cell migration GO:0030334 219 0.014
cellular response to dna damage stimulus GO:0006974 207 0.014
muscle system process GO:0003012 141 0.014
negative regulation of intracellular signal transduction GO:1902532 167 0.014
endocytosis GO:0006897 168 0.014
protein modification by small protein conjugation or removal GO:0070647 207 0.014
carboxylic acid catabolic process GO:0046395 51 0.014
myosin filament assembly GO:0031034 2 0.014
regulation of cell adhesion GO:0030155 154 0.014
skeletal system development GO:0001501 356 0.014
mitochondrion organization GO:0007005 134 0.014
small molecule catabolic process GO:0044282 71 0.014
glycerolipid metabolic process GO:0046486 122 0.014
regulation of cell projection organization GO:0031344 206 0.014
regulation of secretion by cell GO:1903530 249 0.014
reactive nitrogen species metabolic process GO:2001057 0 0.014
epidermis development GO:0008544 187 0.014
response to acid chemical GO:0001101 111 0.014
positive regulation of transferase activity GO:0051347 167 0.014
mitotic cell cycle GO:0000278 195 0.013
regulation of protein transport GO:0051223 163 0.013
ear development GO:0043583 200 0.013
negative regulation of protein modification process GO:0031400 163 0.013
steroid metabolic process GO:0008202 119 0.013
regulation of proteolysis GO:0030162 164 0.013
innate immune response GO:0045087 157 0.013
regulation of intracellular transport GO:0032386 159 0.013
carbohydrate homeostasis GO:0033500 128 0.013
locomotory behavior GO:0007626 195 0.013
organic hydroxy compound transport GO:0015850 93 0.013
wound healing GO:0042060 157 0.013
regulation of system process GO:0044057 200 0.013
regulation of cell motility GO:2000145 236 0.013
myeloid leukocyte differentiation GO:0002573 119 0.013
positive regulation of kinase activity GO:0033674 155 0.013
anion transmembrane transport GO:0098656 71 0.013
lipid transport GO:0006869 98 0.013
action potential GO:0001508 78 0.013
epithelial cell development GO:0002064 159 0.013
alcohol metabolic process GO:0006066 116 0.013
single organism cell adhesion GO:0098602 156 0.013
nucleocytoplasmic transport GO:0006913 139 0.013
placenta development GO:0001890 140 0.013
negative regulation of phosphorylation GO:0042326 166 0.013
purine nucleoside monophosphate metabolic process GO:0009126 81 0.013
organic acid catabolic process GO:0016054 51 0.013
response to radiation GO:0009314 165 0.013
positive regulation of organelle organization GO:0010638 128 0.013
protein localization to plasma membrane GO:0072659 57 0.013
spermatid differentiation GO:0048515 115 0.013
nucleoside monophosphate metabolic process GO:0009123 85 0.013
skeletal muscle organ development GO:0060538 163 0.012
neuron death GO:0070997 154 0.012
divalent inorganic cation homeostasis GO:0072507 138 0.012
epithelial tube morphogenesis GO:0060562 303 0.012
cellular response to acid chemical GO:0071229 68 0.012
cofactor metabolic process GO:0051186 80 0.012
cellular alcohol metabolic process GO:0044107 3 0.012
organelle fission GO:0048285 170 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
epithelial cell proliferation GO:0050673 174 0.012
regulation of transmembrane transport GO:0034762 128 0.012
actin filament organization GO:0007015 113 0.012
monosaccharide metabolic process GO:0005996 106 0.012
defense response to other organism GO:0098542 197 0.012
urogenital system development GO:0001655 261 0.012
ribonucleoside monophosphate metabolic process GO:0009161 80 0.012
sequestering of calcium ion GO:0051208 18 0.012
response to oxygen levels GO:0070482 62 0.012
amino acid transport GO:0006865 61 0.012
glycoprotein metabolic process GO:0009100 116 0.012
positive regulation of cell development GO:0010720 237 0.012
adult behavior GO:0030534 135 0.012
membrane lipid metabolic process GO:0006643 53 0.012
response to light stimulus GO:0009416 135 0.012
gland development GO:0048732 330 0.012
regulation of mitotic cell cycle GO:0007346 126 0.012
regulation of t cell activation GO:0050863 170 0.011
intrinsic apoptotic signaling pathway GO:0097193 132 0.011
regulation of ion transmembrane transport GO:0034765 119 0.011
regulation of nucleotide catabolic process GO:0030811 122 0.011
mitotic cell cycle process GO:1903047 159 0.011
regulation of actin filament based process GO:0032970 99 0.011
calcium ion homeostasis GO:0055074 127 0.011
cell growth GO:0016049 130 0.011
organelle assembly GO:0070925 177 0.011
cytokine mediated signaling pathway GO:0019221 115 0.011
lipid localization GO:0010876 126 0.011
regulation of leukocyte differentiation GO:1902105 159 0.011
renal system development GO:0072001 225 0.011
negative regulation of transferase activity GO:0051348 85 0.011
calcium ion transport GO:0006816 159 0.011
regulation of blood pressure GO:0008217 93 0.011
regulation of inflammatory response GO:0050727 147 0.011
activation of immune response GO:0002253 138 0.011
negative regulation of protein phosphorylation GO:0001933 126 0.011
cellular response to extracellular stimulus GO:0031668 81 0.011
positive regulation of cellular catabolic process GO:0031331 148 0.011
protein modification by small protein conjugation GO:0032446 187 0.011
axonogenesis GO:0007409 274 0.011
cellularization GO:0007349 1 0.011
regulation of cytoplasmic transport GO:1903649 112 0.011
anatomical structure homeostasis GO:0060249 145 0.011
negative regulation of defense response GO:0031348 77 0.011
regulation of endopeptidase activity GO:0052548 89 0.011
cellular response to hormone stimulus GO:0032870 150 0.011
lymphocyte mediated immunity GO:0002449 139 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.011
regulation of cytoskeleton organization GO:0051493 122 0.011
protein localization to nucleus GO:0034504 121 0.011
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
neuron apoptotic process GO:0051402 142 0.011
striated muscle myosin thick filament assembly GO:0071688 1 0.011
guanosine containing compound catabolic process GO:1901069 144 0.011
regulation of neuron projection development GO:0010975 169 0.011
glycoprotein biosynthetic process GO:0009101 89 0.011
embryonic organ morphogenesis GO:0048562 276 0.011
hormone metabolic process GO:0042445 86 0.010
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.010
gtp catabolic process GO:0006184 143 0.010
negative regulation of cell development GO:0010721 169 0.010
cellular protein catabolic process GO:0044257 155 0.010
chemotaxis GO:0006935 247 0.010
lymphocyte differentiation GO:0030098 242 0.010
regulation of cellular component size GO:0032535 121 0.010
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.010
ossification GO:0001503 216 0.010
regulation of lymphocyte proliferation GO:0050670 117 0.010
positive regulation of nucleotide metabolic process GO:0045981 114 0.010
angiogenesis GO:0001525 201 0.010
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.010
methylation GO:0032259 134 0.010
cellular response to lipopolysaccharide GO:0071222 77 0.010
engulfment of apoptotic cell GO:0043652 3 0.010
zygotic determination of anterior posterior axis embryo GO:0007354 3 0.010
amide transport GO:0042886 138 0.010
protein ubiquitination GO:0016567 171 0.010
sequestering of metal ion GO:0051238 19 0.010
ameboidal type cell migration GO:0001667 128 0.010
organophosphate biosynthetic process GO:0090407 122 0.010
chromatin organization GO:0006325 206 0.010
regulation of interleukin 8 production GO:0032677 3 0.010
peptide metabolic process GO:0006518 46 0.010
reactive oxygen species biosynthetic process GO:1903409 8 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.010
sodium ion transport GO:0006814 73 0.010
regulation of vesicle mediated transport GO:0060627 139 0.010
cellular alcohol biosynthetic process GO:0044108 3 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.010
exocytosis GO:0006887 121 0.010
response to nutrient levels GO:0031667 109 0.010

Gss disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
nervous system disease DOID:863 0 0.028
disease of metabolism DOID:0014667 0 0.021
inherited metabolic disorder DOID:655 0 0.021
immune system disease DOID:2914 0 0.017
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
organ system cancer DOID:0050686 0 0.016
musculoskeletal system disease DOID:17 0 0.015
sensory system disease DOID:0050155 0 0.014
hematopoietic system disease DOID:74 0 0.013
central nervous system disease DOID:331 0 0.011
eye and adnexa disease DOID:1492 0 0.011
eye disease DOID:5614 0 0.010