Mus musculus

21 known processes

Defa4

defensin, alpha, 4

(Aliases: Defcr4,Crp4,Defa28)

Defa4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nucleobase containing small molecule metabolic process GO:0055086 352 0.056
purine containing compound metabolic process GO:0072521 311 0.048
nucleotide metabolic process GO:0009117 332 0.047
cardiac muscle cell contraction GO:0086003 7 0.046
purine nucleotide metabolic process GO:0006163 302 0.046
ion transmembrane transport GO:0034220 361 0.044
positive regulation of cellular amine metabolic process GO:0033240 5 0.044
regulation of nucleotide metabolic process GO:0006140 169 0.043
purine ribonucleotide metabolic process GO:0009150 290 0.041
small gtpase mediated signal transduction GO:0007264 97 0.039
transmembrane transport GO:0055085 412 0.039
nucleoside triphosphate metabolic process GO:0009141 230 0.038
sa node cell action potential GO:0086015 4 0.035
regulation of purine nucleotide metabolic process GO:1900542 169 0.034
regulation of hydrolase activity GO:0051336 246 0.034
regulation of cellular amino acid metabolic process GO:0006521 5 0.033
ribonucleotide metabolic process GO:0009259 291 0.033
cation transmembrane transport GO:0098655 266 0.032
protein processing GO:0016485 163 0.032
actin filament based movement GO:0030048 23 0.031
negative regulation of cellular protein metabolic process GO:0032269 247 0.031
spermatogenesis GO:0007283 284 0.031
regulation of cellular catabolic process GO:0031329 242 0.030
hematopoietic progenitor cell differentiation GO:0002244 143 0.030
muscle system process GO:0003012 141 0.028
oxidation reduction process GO:0055114 342 0.028
regulation of cellular amine metabolic process GO:0033238 20 0.027
purine nucleoside metabolic process GO:0042278 241 0.027
protein ubiquitination GO:0016567 171 0.026
inorganic cation transmembrane transport GO:0098662 207 0.026
posttranscriptional regulation of gene expression GO:0010608 155 0.026
protein maturation GO:0051604 176 0.026
sa node cell to atrial cardiac muscle cell signalling GO:0086018 4 0.026
purine nucleoside triphosphate metabolic process GO:0009144 226 0.025
response to organonitrogen compound GO:0010243 246 0.025
cellular response to lipopolysaccharide GO:0071222 77 0.025
response to organic cyclic compound GO:0014070 198 0.025
cellular ketone metabolic process GO:0042180 84 0.025
nucleoside phosphate metabolic process GO:0006753 338 0.025
purine ribonucleotide catabolic process GO:0009154 208 0.025
ribose phosphate metabolic process GO:0019693 291 0.024
organophosphate catabolic process GO:0046434 232 0.024
carbohydrate derivative catabolic process GO:1901136 231 0.023
regulation of protein kinase activity GO:0045859 232 0.023
ribonucleoside catabolic process GO:0042454 206 0.023
regulation of proteolysis GO:0030162 164 0.022
organonitrogen compound catabolic process GO:1901565 264 0.022
nucleoside phosphate catabolic process GO:1901292 222 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.022
amine metabolic process GO:0009308 45 0.022
ras protein signal transduction GO:0007265 77 0.021
nucleoside metabolic process GO:0009116 246 0.021
carbohydrate metabolic process GO:0005975 230 0.021
positive regulation of transferase activity GO:0051347 167 0.021
regulation of nucleoside metabolic process GO:0009118 130 0.020
multi multicellular organism process GO:0044706 109 0.020
purine ribonucleoside metabolic process GO:0046128 241 0.020
response to lipopolysaccharide GO:0032496 128 0.020
male gamete generation GO:0048232 285 0.020
ribonucleoside metabolic process GO:0009119 245 0.020
negative regulation of proteolysis GO:0045861 74 0.020
regulation of membrane potential GO:0042391 192 0.020
ribonucleoside triphosphate metabolic process GO:0009199 220 0.019
cellular response to biotic stimulus GO:0071216 92 0.019
regulation of cellular ketone metabolic process GO:0010565 66 0.019
regulation of body fluid levels GO:0050878 162 0.019
regulation of blood circulation GO:1903522 93 0.019
blood circulation GO:0008015 195 0.019
intrinsic apoptotic signaling pathway GO:0097193 132 0.019
cellular nitrogen compound catabolic process GO:0044270 280 0.019
nucleotide catabolic process GO:0009166 217 0.019
cellular amine metabolic process GO:0044106 44 0.019
macromolecule methylation GO:0043414 120 0.018
purine ribonucleoside catabolic process GO:0046130 205 0.018
glycosyl compound catabolic process GO:1901658 206 0.018
heterocycle catabolic process GO:0046700 280 0.018
cellular protein catabolic process GO:0044257 155 0.018
nitrogen compound transport GO:0071705 271 0.018
peptidyl amino acid modification GO:0018193 336 0.018
organonitrogen compound biosynthetic process GO:1901566 192 0.018
aromatic compound catabolic process GO:0019439 286 0.018
response to radiation GO:0009314 165 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.018
compound eye development GO:0048749 1 0.018
embryonic placenta development GO:0001892 98 0.018
cellular response to cytokine stimulus GO:0071345 189 0.017
ribonucleoside triphosphate catabolic process GO:0009203 199 0.017
regulation of transferase activity GO:0051338 263 0.017
regulation of cellular component biogenesis GO:0044087 181 0.017
purine nucleoside catabolic process GO:0006152 205 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.017
purine nucleotide catabolic process GO:0006195 211 0.017
glycosyl compound metabolic process GO:1901657 246 0.017
protein catabolic process GO:0030163 221 0.017
negative regulation of molecular function GO:0044092 258 0.017
negative regulation of protein metabolic process GO:0051248 282 0.017
circulatory system process GO:0003013 197 0.017
cellular response to hormone stimulus GO:0032870 150 0.017
negative regulation of endopeptidase activity GO:0010951 44 0.017
protein modification by small protein conjugation or removal GO:0070647 207 0.016
regulation of cell cycle GO:0051726 281 0.016
cell cell junction organization GO:0045216 72 0.016
nucleoside triphosphate catabolic process GO:0009143 205 0.016
cellular amino acid metabolic process GO:0006520 103 0.016
actin mediated cell contraction GO:0070252 15 0.016
rho protein signal transduction GO:0007266 32 0.016
regulation of ion transmembrane transport GO:0034765 119 0.016
milk ejection GO:0060156 1 0.016
cellular response to lipid GO:0071396 145 0.016
cellular response to organonitrogen compound GO:0071417 145 0.016
regulation of organelle organization GO:0033043 289 0.015
regulation of protein catabolic process GO:0042176 108 0.015
ribonucleotide catabolic process GO:0009261 208 0.015
regulation of protein processing GO:0070613 96 0.015
regulation of actin filament based process GO:0032970 99 0.015
organic cyclic compound catabolic process GO:1901361 295 0.015
apoptotic signaling pathway GO:0097190 306 0.015
regulation of kinase activity GO:0043549 249 0.015
generation of precursor metabolites and energy GO:0006091 103 0.015
lipid biosynthetic process GO:0008610 179 0.015
av node cell to bundle of his cell communication GO:0086067 2 0.015
membrane depolarization during sa node cell action potential GO:0086046 2 0.015
response to light stimulus GO:0009416 135 0.015
cellular response to molecule of bacterial origin GO:0071219 83 0.015
protein modification by small protein conjugation GO:0032446 187 0.015
regulation of system process GO:0044057 200 0.015
carboxylic acid transport GO:0046942 100 0.015
heart process GO:0003015 94 0.014
negative regulation of hydrolase activity GO:0051346 71 0.014
cellular protein complex assembly GO:0043623 116 0.014
striated muscle contraction GO:0006941 45 0.014
nuclear division GO:0000280 158 0.014
regulation of muscle system process GO:0090257 80 0.014
regulation of protein maturation GO:1903317 96 0.014
regulation of blood pressure GO:0008217 93 0.014
cation homeostasis GO:0055080 212 0.014
cellular alcohol biosynthetic process GO:0044108 3 0.014
multicellular organismal signaling GO:0035637 91 0.014
negative regulation of protein processing GO:0010955 79 0.014
spermatid differentiation GO:0048515 115 0.014
purine containing compound catabolic process GO:0072523 213 0.013
cellular macromolecule catabolic process GO:0044265 206 0.013
positive regulation of kinase activity GO:0033674 155 0.013
muscle contraction GO:0006936 101 0.013
response to molecule of bacterial origin GO:0002237 143 0.013
positive regulation of protein modification process GO:0031401 299 0.013
cellular carbohydrate metabolic process GO:0044262 119 0.013
negative regulation of phosphorus metabolic process GO:0010563 184 0.013
regulation of purine nucleotide catabolic process GO:0033121 122 0.013
midgut development GO:0007494 4 0.013
carbohydrate derivative biosynthetic process GO:1901137 183 0.013
cellular response to dna damage stimulus GO:0006974 207 0.013
skeletal system development GO:0001501 356 0.013
response to inorganic substance GO:0010035 96 0.013
monocarboxylic acid metabolic process GO:0032787 191 0.013
metal ion homeostasis GO:0055065 189 0.013
macromolecule catabolic process GO:0009057 281 0.013
atp metabolic process GO:0046034 75 0.012
regulation of ion transport GO:0043269 215 0.012
calcitriol biosynthetic process from calciol GO:0036378 3 0.012
divalent inorganic cation homeostasis GO:0072507 138 0.012
regulation of transmembrane transport GO:0034762 128 0.012
reactive nitrogen species metabolic process GO:2001057 0 0.012
regulation of nucleotide catabolic process GO:0030811 122 0.012
regulation of cell cycle process GO:0010564 160 0.012
vitamin d biosynthetic process GO:0042368 3 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.012
negative regulation of protein maturation GO:1903318 79 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.012
organelle fission GO:0048285 170 0.012
negative regulation of cell cycle GO:0045786 123 0.012
negative regulation of peptidase activity GO:0010466 46 0.012
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.012
ubiquitin dependent protein catabolic process GO:0006511 129 0.012
protein localization to organelle GO:0033365 185 0.012
action potential GO:0001508 78 0.012
nucleoside catabolic process GO:0009164 206 0.012
fertilization GO:0009566 127 0.012
placenta development GO:0001890 140 0.012
negative regulation of phosphate metabolic process GO:0045936 184 0.011
cation transport GO:0006812 399 0.011
peptidyl tyrosine phosphorylation GO:0018108 143 0.011
fatty acid metabolic process GO:0006631 121 0.011
regulation of mapk cascade GO:0043408 248 0.011
locomotory behavior GO:0007626 195 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
organophosphate biosynthetic process GO:0090407 122 0.011
negative regulation of ubiquitin protein transferase activity GO:0051444 3 0.011
cardiac muscle contraction GO:0060048 32 0.011
single organism cell adhesion GO:0098602 156 0.011
regulation of protein transport GO:0051223 163 0.011
sensory perception GO:0007600 245 0.011
mitotic cell cycle process GO:1903047 159 0.011
cellular chemical homeostasis GO:0055082 215 0.011
anatomical structure homeostasis GO:0060249 145 0.011
nucleoside monophosphate metabolic process GO:0009123 85 0.011
monovalent inorganic cation homeostasis GO:0055067 33 0.011
muscle cell differentiation GO:0042692 261 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.011
positive regulation of apoptotic signaling pathway GO:2001235 95 0.010
negative regulation of protein modification process GO:0031400 163 0.010
inorganic ion transmembrane transport GO:0098660 234 0.010
cellular alcohol metabolic process GO:0044107 3 0.010
cell adhesion GO:0007155 329 0.010
peptide hormone secretion GO:0030072 109 0.010
regulation of cell activation GO:0050865 289 0.010
innate immune response GO:0045087 157 0.010

Defa4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.011
nervous system disease DOID:863 0 0.011
musculoskeletal system disease DOID:17 0 0.011