|
|
dna metabolic process
|
GO:0006259 |
303 |
0.712
|
|
|
|
natural killer cell differentiation
|
GO:0001779 |
21 |
0.625
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.618
|
|
|
|
mucosal associated lymphoid tissue development
|
GO:0048537 |
12 |
0.544
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.532
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.506
|
|
|
|
gonad morphogenesis
|
GO:0035262 |
1 |
0.400
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.390
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.377
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.375
|
|
|
|
stem cell fate specification
|
GO:0048866 |
3 |
0.354
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.353
|
Human |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.351
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.344
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.336
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.330
|
|
|
|
neuroblast differentiation
|
GO:0014016 |
2 |
0.329
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.329
|
|
|
|
somatic diversification of immune receptors via germline recombination within a single locus
|
GO:0002562 |
51 |
0.319
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.317
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.311
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.304
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.303
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.286
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.284
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.247
|
|
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
26 |
0.246
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.242
|
Mouse |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.232
|
Zebrafish |
|
|
angiogenesis
|
GO:0001525 |
201 |
0.227
|
Mouse |
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.220
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.218
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.214
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.207
|
|
|
|
neuroblast fate commitment
|
GO:0014017 |
1 |
0.207
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.201
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.199
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.197
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.193
|
|
|
|
v d j recombination
|
GO:0033151 |
14 |
0.186
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.184
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.183
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.181
|
|
|
|
somatic cell dna recombination
|
GO:0016444 |
51 |
0.179
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.175
|
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.174
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.173
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.165
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
39 |
0.164
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.164
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.163
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.162
|
|
|
|
negative regulation of osteoblast differentiation
|
GO:0045668 |
30 |
0.161
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.159
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.158
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.156
|
|
|
|
skeletal muscle fiber development
|
GO:0048741 |
58 |
0.155
|
Mouse |
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.155
|
|
|
|
organic anion transport
|
GO:0015711 |
137 |
0.153
|
|
|
|
oligodendrocyte differentiation
|
GO:0048709 |
53 |
0.152
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.151
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.151
|
|
|
|
anion transport
|
GO:0006820 |
177 |
0.146
|
|
|
|
somatic recombination of immunoglobulin gene segments
|
GO:0016447 |
42 |
0.146
|
|
|
|
regulation of myoblast differentiation
|
GO:0045661 |
29 |
0.145
|
Mouse |
|
|
gonad development
|
GO:0008406 |
141 |
0.144
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.143
|
Fly |
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.142
|
|
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
30 |
0.141
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.139
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.138
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.137
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.134
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.134
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.133
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.133
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.129
|
|
|
|
somatic diversification of immunoglobulins
|
GO:0016445 |
43 |
0.128
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.128
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.127
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.126
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.126
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.125
|
|
|
|
glucose transport
|
GO:0015758 |
56 |
0.125
|
|
|
|
positive regulation of translational initiation
|
GO:0045948 |
4 |
0.125
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.124
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.123
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.123
|
|
|
|
central nervous system neuron differentiation
|
GO:0021953 |
162 |
0.123
|
Mouse |
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.119
|
|
|
|
dna recombination
|
GO:0006310 |
92 |
0.119
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.119
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.119
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.117
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.117
|
|
|
|
mammary gland epithelial cell proliferation
|
GO:0033598 |
24 |
0.117
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.114
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.114
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.114
|
|
|
|
lymph node development
|
GO:0048535 |
18 |
0.113
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.113
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.113
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.112
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
106 |
0.112
|
|
|
|
oligodendrocyte development
|
GO:0014003 |
20 |
0.111
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.110
|
Human Zebrafish Mouse |
|
|
response to growth factor
|
GO:0070848 |
198 |
0.110
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.108
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.108
|
|
|
|
regulation of protein stability
|
GO:0031647 |
52 |
0.106
|
Mouse |
|
|
skeletal system development
|
GO:0001501 |
356 |
0.106
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.105
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.105
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.104
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.102
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.102
|
Mouse |
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.102
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.101
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
3 |
0.101
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.098
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.097
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.097
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.097
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.097
|
Mouse |
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.097
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.096
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.095
|
|
|
|
immunoglobulin v d j recombination
|
GO:0033152 |
5 |
0.095
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.095
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.095
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.095
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.095
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.094
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.093
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.092
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.092
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.092
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.091
|
|
|
|
somatic diversification of immune receptors
|
GO:0002200 |
53 |
0.091
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.091
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.090
|
Mouse |
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.088
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.088
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.088
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.088
|
|
|
|
positive regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000451 |
2 |
0.088
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.087
|
|
|
|
positive regulation of translational initiation by iron
|
GO:0045994 |
2 |
0.087
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.086
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.085
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.085
|
|
|
|
hair follicle development
|
GO:0001942 |
85 |
0.084
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.084
|
Mouse |
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.084
|
Mouse |
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.083
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.083
|
Fly |
|
|
positive regulation of homeostatic process
|
GO:0032846 |
64 |
0.082
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.082
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.082
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.081
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.080
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.080
|
|
|
|
glucose metabolic process
|
GO:0006006 |
92 |
0.078
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.077
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.077
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.077
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
40 |
0.076
|
Human |
|
|
protein targeting
|
GO:0006605 |
143 |
0.076
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.075
|
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.075
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.075
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.075
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.075
|
|
|
|
organic acid transport
|
GO:0015849 |
101 |
0.075
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.075
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.075
|
|
|
|
positive regulation of myoblast differentiation
|
GO:0045663 |
8 |
0.074
|
|
|
|
axon ensheathment
|
GO:0008366 |
76 |
0.074
|
Mouse |
|
|
natural killer cell activation
|
GO:0030101 |
44 |
0.073
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.073
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.073
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.073
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.072
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.072
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.072
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.071
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.071
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.071
|
|
|
|
regulation of jun kinase activity
|
GO:0043506 |
40 |
0.070
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.070
|
|
|
|
regulation of oligodendrocyte differentiation
|
GO:0048713 |
23 |
0.070
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.070
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.070
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.070
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.070
|
|
|
|
negative regulation of b cell activation
|
GO:0050869 |
27 |
0.069
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.069
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.069
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.069
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.069
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.069
|
|
|
|
positive regulation of osteoclast differentiation
|
GO:0045672 |
15 |
0.069
|
|
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
82 |
0.069
|
Fly |
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.069
|
|
|
|
carbohydrate transport
|
GO:0008643 |
62 |
0.068
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
27 |
0.067
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.067
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.066
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.066
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.066
|
|
|
|
regulation of anion transport
|
GO:0044070 |
27 |
0.066
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.066
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.066
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.065
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.065
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.065
|
|
|
|
peyer s patch development
|
GO:0048541 |
12 |
0.064
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.064
|
|
|
|
negative regulation of ossification
|
GO:0030279 |
49 |
0.064
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.064
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.063
|
|
|
|
eosinophil activation involved in immune response
|
GO:0002278 |
1 |
0.063
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.063
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.063
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.063
|
|
|
|
positive regulation of hormone secretion
|
GO:0046887 |
38 |
0.063
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.063
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.062
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.062
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.062
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.062
|
|
|
|
response to drug
|
GO:0042493 |
75 |
0.062
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.062
|
|
|
|
monosaccharide transport
|
GO:0015749 |
58 |
0.061
|
|
|
|
spermatid development
|
GO:0007286 |
108 |
0.061
|
Fly |
|
|
carboxylic acid transport
|
GO:0046942 |
100 |
0.061
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.061
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.060
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.059
|
Mouse |
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.059
|
|
|
|
motor neuron migration
|
GO:0097475 |
4 |
0.058
|
|
|
|
regulation of osteoclast differentiation
|
GO:0045670 |
36 |
0.058
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.058
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.058
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.058
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
57 |
0.058
|
Human Mouse |
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.057
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.057
|
Mouse |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.057
|
|
|
|
positive regulation of antibacterial peptide biosynthetic process
|
GO:0006963 |
1 |
0.057
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.057
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.057
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.057
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.056
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.056
|
Fly |
|
|
stem cell development
|
GO:0048864 |
219 |
0.056
|
|
|
|
histone acetylation
|
GO:0016573 |
41 |
0.056
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.056
|
|
|
|
epithelial cell differentiation involved in mammary gland alveolus development
|
GO:0061030 |
4 |
0.056
|
|
|
|
neuroepithelial cell differentiation
|
GO:0060563 |
37 |
0.055
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.055
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.055
|
|
|
|
cellular response to inorganic substance
|
GO:0071241 |
37 |
0.055
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
82 |
0.055
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.055
|
|
|
|
humoral immune response
|
GO:0006959 |
57 |
0.054
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.054
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.054
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
55 |
0.054
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.054
|
Mouse |
|
|
gliogenesis
|
GO:0042063 |
141 |
0.054
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
42 |
0.053
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.053
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.053
|
|
|
|
inflammatory response to antigenic stimulus
|
GO:0002437 |
30 |
0.053
|
|
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.052
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.052
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
27 |
0.052
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.052
|
|
|
|
positive regulation of b cell proliferation
|
GO:0030890 |
24 |
0.052
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.052
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.052
|
|
|
|
peptide secretion
|
GO:0002790 |
114 |
0.052
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.052
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.051
|
|
|
|
necrotic cell death
|
GO:0070265 |
30 |
0.051
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.051
|
Mouse |
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.051
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
52 |
0.051
|
Fly |
|
|
defense response to gram positive bacterium
|
GO:0050830 |
50 |
0.051
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.051
|
|
|
|
stem cell fate commitment
|
GO:0048865 |
5 |
0.051
|
|
|
|
somatic diversification of immunoglobulins involved in immune response
|
GO:0002208 |
36 |
0.051
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.051
|
Mouse |
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.050
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
93 |
0.050
|
Mouse |
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
57 |
0.050
|
Human Mouse |
|
|
regulation of inflammatory response to antigenic stimulus
|
GO:0002861 |
21 |
0.050
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.050
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.050
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.050
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.050
|
|
|
|
protein acylation
|
GO:0043543 |
64 |
0.049
|
|
|
|
positive regulation of chronic inflammatory response
|
GO:0002678 |
4 |
0.049
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.049
|
|
|
|
regulation of hair cycle
|
GO:0042634 |
11 |
0.049
|
|
|
|
eye photoreceptor cell development
|
GO:0042462 |
31 |
0.049
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.049
|
|
|
|
lipid transport
|
GO:0006869 |
98 |
0.049
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.049
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.049
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.049
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.048
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.048
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.048
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.048
|
|
|
|
regulation of peptide hormone secretion
|
GO:0090276 |
75 |
0.048
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.048
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.048
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.048
|
|
|
|
regulation of translation
|
GO:0006417 |
71 |
0.048
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.048
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.047
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
47 |
0.047
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.047
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.047
|
|
|
|
glial cell apoptotic process
|
GO:0034349 |
3 |
0.047
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.047
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.046
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.046
|
Mouse |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.046
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.046
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.046
|
|
|
|
regulation of glycogen catabolic process
|
GO:0005981 |
2 |
0.046
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.046
|
|
|
|
ensheathment of neurons
|
GO:0007272 |
76 |
0.046
|
Mouse |
|
|
protein import
|
GO:0017038 |
101 |
0.046
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
98 |
0.046
|
|
|
|
immune complex clearance
|
GO:0002434 |
2 |
0.046
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.046
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.045
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.045
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.045
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.045
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.045
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.044
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.044
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.044
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.044
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.044
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.044
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.043
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
65 |
0.043
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.043
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.043
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.043
|
|
|
|
mammary gland lobule development
|
GO:0061377 |
22 |
0.043
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.043
|
|
|
|
cell fate specification
|
GO:0001708 |
72 |
0.043
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
26 |
0.042
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.042
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.042
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.042
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.042
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.042
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.042
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.041
|
|
|
|
regulation of myotube differentiation
|
GO:0010830 |
62 |
0.041
|
Mouse |
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.041
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.041
|
|
|
|
odontogenesis
|
GO:0042476 |
78 |
0.041
|
Mouse |
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
39 |
0.041
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.041
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.041
|
|
|
|
necroptotic signaling pathway
|
GO:0097527 |
3 |
0.041
|
|
|
|
hexose metabolic process
|
GO:0019318 |
98 |
0.041
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.041
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.041
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
11 |
0.040
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.040
|
|
|
|
retinal cell programmed cell death
|
GO:0046666 |
8 |
0.040
|
|
|
|
cell cycle arrest
|
GO:0007050 |
37 |
0.040
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
42 |
0.040
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.040
|
|
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.039
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
68 |
0.039
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.039
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.039
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.039
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
43 |
0.039
|
|
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.039
|
|
|
|
response to antibiotic
|
GO:0046677 |
11 |
0.039
|
Mouse |
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.039
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.039
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.039
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.039
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
60 |
0.039
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.038
|
Human Zebrafish |
|
|
peptide transport
|
GO:0015833 |
133 |
0.038
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.038
|
|
|
|
hormone secretion
|
GO:0046879 |
128 |
0.038
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.038
|
Mouse |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.038
|
|
|
|
positive regulation of glial cell differentiation
|
GO:0045687 |
21 |
0.038
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.038
|
|
|
|
enucleate erythrocyte differentiation
|
GO:0043353 |
8 |
0.038
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.038
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.037
|
|
|
|
positive regulation of gliogenesis
|
GO:0014015 |
27 |
0.037
|
|
|
|
primary neural tube formation
|
GO:0014020 |
95 |
0.037
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
53 |
0.037
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.037
|
|
|
|
osteoclast proliferation
|
GO:0002158 |
4 |
0.037
|
|
|
|
cerebral cortex development
|
GO:0021987 |
86 |
0.037
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
77 |
0.037
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.037
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.037
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.037
|
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.037
|
|
|
|
hexose transport
|
GO:0008645 |
56 |
0.036
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.036
|
|
|
|
regulation of translational initiation by iron
|
GO:0006447 |
2 |
0.036
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.036
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.036
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.036
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.036
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.036
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.036
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.036
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.036
|
|
|
|
regulation of gliogenesis
|
GO:0014013 |
50 |
0.036
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.036
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.035
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
67 |
0.035
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.035
|
|
|
|
secondary metabolic process
|
GO:0019748 |
18 |
0.035
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.035
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.035
|
|
|
|
muscle fiber development
|
GO:0048747 |
76 |
0.035
|
Mouse |
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.035
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.034
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.034
|
|
|
|
monocarboxylic acid transport
|
GO:0015718 |
44 |
0.034
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.034
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
81 |
0.034
|
Mouse |
|
|
mammary gland alveolus development
|
GO:0060749 |
22 |
0.034
|
|
|
|
meiotic cell cycle process
|
GO:1903046 |
77 |
0.034
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.033
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.033
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.033
|
|
|
|
regulation of epidermis development
|
GO:0045682 |
33 |
0.033
|
|
|
|
t cell migration
|
GO:0072678 |
19 |
0.033
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.033
|
|
|
|
liver development
|
GO:0001889 |
66 |
0.033
|
|
|
|
ear development
|
GO:0043583 |
200 |
0.033
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
32 |
0.033
|
|
|
|
circadian regulation of gene expression
|
GO:0032922 |
48 |
0.033
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.033
|
|
|
|
positive regulation of peptide hormone secretion
|
GO:0090277 |
31 |
0.033
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
65 |
0.032
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.032
|
|
|
|
regulation of erythrocyte differentiation
|
GO:0045646 |
23 |
0.032
|
|
|
|
lateral inhibition
|
GO:0046331 |
1 |
0.032
|
Fly |
|
|
mammary gland epithelium development
|
GO:0061180 |
65 |
0.032
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.032
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.032
|
Mouse |
|
|
regulation of b cell differentiation
|
GO:0045577 |
23 |
0.032
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.032
|
|
|
|
cd8 positive alpha beta t cell extravasation
|
GO:0035697 |
3 |
0.032
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.032
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.032
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.032
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
56 |
0.032
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.032
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.032
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.032
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.031
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
61 |
0.031
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.031
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.031
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.031
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.031
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.031
|
|
|
|
response to lithium ion
|
GO:0010226 |
10 |
0.031
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.031
|
|
|
|
positive regulation of peptide secretion
|
GO:0002793 |
33 |
0.031
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
45 |
0.031
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.031
|
|
|
|
neural tube formation
|
GO:0001841 |
108 |
0.031
|
|
|
|
glial cell development
|
GO:0021782 |
54 |
0.031
|
|
|
|
regulation of blood pressure
|
GO:0008217 |
93 |
0.031
|
|
|
|
positive regulation of interleukin 12 production
|
GO:0032735 |
21 |
0.030
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.030
|
|
|
|
central nervous system neuron development
|
GO:0021954 |
67 |
0.030
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.030
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
38 |
0.030
|
|
|
|
zymogen activation
|
GO:0031638 |
41 |
0.030
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.030
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.030
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.030
|
|
