Mus musculus

0 known processes

Ide

insulin degrading enzyme

(Aliases: AA675336,1300012G03Rik,AI507533,4833415K22Rik)

Ide biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
membrane organization GO:0061024 245 0.092
cellular amino acid metabolic process GO:0006520 103 0.070
macromolecule catabolic process GO:0009057 281 0.065
Human
protein catabolic process GO:0030163 221 0.064
Human
cellular response to dna damage stimulus GO:0006974 207 0.058
nucleobase containing small molecule metabolic process GO:0055086 352 0.058
regulation of membrane potential GO:0042391 192 0.057
negative regulation of protein metabolic process GO:0051248 282 0.053
intracellular protein transport GO:0006886 204 0.053
regulation of cellular catabolic process GO:0031329 242 0.052
heterocycle catabolic process GO:0046700 280 0.050
mitochondrion organization GO:0007005 134 0.050
regulation of translation GO:0006417 71 0.046
regulation of apoptotic signaling pathway GO:2001233 197 0.046
transmission of nerve impulse GO:0019226 76 0.044
organelle disassembly GO:1903008 2 0.044
translation GO:0006412 93 0.040
ribose phosphate metabolic process GO:0019693 291 0.038
action potential GO:0001508 78 0.037
aromatic compound catabolic process GO:0019439 286 0.034
maintenance of location GO:0051235 89 0.034
protein modification by small protein conjugation or removal GO:0070647 207 0.033
regulation of organelle organization GO:0033043 289 0.033
apoptotic signaling pathway GO:0097190 306 0.033
purine nucleoside metabolic process GO:0042278 241 0.033
ion transmembrane transport GO:0034220 361 0.033
neuronal action potential GO:0019228 54 0.032
multicellular organismal signaling GO:0035637 91 0.032
amine metabolic process GO:0009308 45 0.032
carbohydrate metabolic process GO:0005975 230 0.031
cellular nitrogen compound catabolic process GO:0044270 280 0.031
ribonucleoside metabolic process GO:0009119 245 0.031
male gamete generation GO:0048232 285 0.031
coenzyme metabolic process GO:0006732 52 0.031
cellular ketone metabolic process GO:0042180 84 0.030
intrinsic apoptotic signaling pathway GO:0097193 132 0.030
oxidation reduction process GO:0055114 342 0.029
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.029
mitochondrion distribution GO:0048311 4 0.028
nucleoside phosphate metabolic process GO:0006753 338 0.028
cellular amine metabolic process GO:0044106 44 0.028
cellular protein catabolic process GO:0044257 155 0.028
Human
organic cyclic compound catabolic process GO:1901361 295 0.028
organophosphate catabolic process GO:0046434 232 0.028
cellular macromolecule catabolic process GO:0044265 206 0.028
Human
protein localization to membrane GO:0072657 108 0.027
inorganic ion transmembrane transport GO:0098660 234 0.027
spermatogenesis GO:0007283 284 0.027
nucleotide metabolic process GO:0009117 332 0.027
negative regulation of cellular protein metabolic process GO:0032269 247 0.026
purine nucleotide metabolic process GO:0006163 302 0.026
glycosyl compound metabolic process GO:1901657 246 0.026
regulation of establishment of protein localization GO:0070201 181 0.026
small gtpase mediated signal transduction GO:0007264 97 0.026
chromatin organization GO:0006325 206 0.026
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.025
Human
organonitrogen compound catabolic process GO:1901565 264 0.025
Human
nucleoside metabolic process GO:0009116 246 0.024
cation transport GO:0006812 399 0.024
transmembrane transport GO:0055085 412 0.024
cellular lipid metabolic process GO:0044255 323 0.023
protein localization to organelle GO:0033365 185 0.023
purine containing compound metabolic process GO:0072521 311 0.023
response to organonitrogen compound GO:0010243 246 0.022
sulfur compound metabolic process GO:0006790 100 0.022
establishment of protein localization to organelle GO:0072594 118 0.022
ribonucleotide metabolic process GO:0009259 291 0.022
positive regulation of hydrolase activity GO:0051345 148 0.022
protein import GO:0017038 101 0.022
ras protein signal transduction GO:0007265 77 0.022
myelination GO:0042552 74 0.022
dna repair GO:0006281 107 0.021
response to oxidative stress GO:0006979 123 0.021
regulation of intracellular transport GO:0032386 159 0.021
organonitrogen compound biosynthetic process GO:1901566 192 0.021
regulation of cellular amino acid metabolic process GO:0006521 5 0.021
cation transmembrane transport GO:0098655 266 0.021
regulation of cellular ketone metabolic process GO:0010565 66 0.021
divalent metal ion transport GO:0070838 172 0.021
cellular homeostasis GO:0019725 240 0.020
Human
protein targeting GO:0006605 143 0.020
carbohydrate derivative catabolic process GO:1901136 231 0.020
regulation of hydrolase activity GO:0051336 246 0.020
regulation of protein transport GO:0051223 163 0.020
purine ribonucleoside metabolic process GO:0046128 241 0.020
response to reactive oxygen species GO:0000302 56 0.019
negative regulation of immune system process GO:0002683 209 0.019
positive regulation of cell death GO:0010942 224 0.019
establishment of mitochondrion localization GO:0051654 4 0.019
dna metabolic process GO:0006259 303 0.019
cytoplasmic transport GO:0016482 234 0.019
posttranscriptional regulation of gene expression GO:0010608 155 0.019
regulation of cellular component biogenesis GO:0044087 181 0.019
Human
negative regulation of cellular component organization GO:0051129 194 0.019
anatomical structure homeostasis GO:0060249 145 0.018
regulation of transmembrane transport GO:0034762 128 0.018
protein import into nucleus GO:0006606 95 0.018
telencephalon development GO:0021537 186 0.018
forebrain development GO:0030900 302 0.018
ensheathment of neurons GO:0007272 76 0.018
lipid biosynthetic process GO:0008610 179 0.018
ribonucleotide catabolic process GO:0009261 208 0.018
endomembrane system organization GO:0010256 147 0.017
single organism nuclear import GO:1902593 95 0.017
regulation of anatomical structure size GO:0090066 178 0.017
response to endoplasmic reticulum stress GO:0034976 53 0.017
modification dependent macromolecule catabolic process GO:0043632 133 0.017
nucleoside catabolic process GO:0009164 206 0.017
lateral inhibition GO:0046331 1 0.017
purine nucleotide catabolic process GO:0006195 211 0.017
regulation of ion transmembrane transport GO:0034765 119 0.017
regulation of cell activation GO:0050865 289 0.017
protein maturation GO:0051604 176 0.017
ribonucleoside triphosphate metabolic process GO:0009199 220 0.017
spermatid differentiation GO:0048515 115 0.017
multicellular organismal homeostasis GO:0048871 164 0.017
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.017
ubiquitin dependent protein catabolic process GO:0006511 129 0.017
striated muscle tissue development GO:0014706 293 0.016
inorganic cation transmembrane transport GO:0098662 207 0.016
plasma membrane organization GO:0007009 90 0.016
positive regulation of cellular amine metabolic process GO:0033240 5 0.016
monocarboxylic acid metabolic process GO:0032787 191 0.016
dephosphorylation GO:0016311 129 0.016
nucleocytoplasmic transport GO:0006913 139 0.016
endocytosis GO:0006897 168 0.016
chromatin modification GO:0016568 187 0.016
regulation of ion transport GO:0043269 215 0.016
cation homeostasis GO:0055080 212 0.016
ribonucleoside catabolic process GO:0042454 206 0.016
positive regulation of protein modification process GO:0031401 299 0.015
nuclear import GO:0051170 95 0.015
purine nucleoside catabolic process GO:0006152 205 0.015
regulation of system process GO:0044057 200 0.015
purine nucleoside triphosphate metabolic process GO:0009144 226 0.015
divalent inorganic cation transport GO:0072511 178 0.015
ossification GO:0001503 216 0.015
circulatory system process GO:0003013 197 0.015
positive regulation of cellular catabolic process GO:0031331 148 0.015
metencephalon development GO:0022037 89 0.015
regulation of protein localization GO:0032880 231 0.015
glycosyl compound catabolic process GO:1901658 206 0.015
cell type specific apoptotic process GO:0097285 268 0.015
negative regulation of apoptotic signaling pathway GO:2001234 104 0.015
sensory perception GO:0007600 245 0.015
alcohol metabolic process GO:0006066 116 0.015
compound eye development GO:0048749 1 0.015
purine containing compound catabolic process GO:0072523 213 0.015
purine ribonucleoside catabolic process GO:0046130 205 0.014
muscle tissue development GO:0060537 308 0.014
nucleoside phosphate catabolic process GO:1901292 222 0.014
cellular response to organonitrogen compound GO:0071417 145 0.014
coenzyme biosynthetic process GO:0009108 23 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.014
calcium ion transport GO:0006816 159 0.014
regulation of cellular amine metabolic process GO:0033238 20 0.014
homeostasis of number of cells GO:0048872 210 0.014
regulation of defense response GO:0031347 233 0.014
carbohydrate derivative biosynthetic process GO:1901137 183 0.014
organelle fission GO:0048285 170 0.014
regulation of protein catabolic process GO:0042176 108 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.014
cellular chemical homeostasis GO:0055082 215 0.014
ribonucleoside triphosphate catabolic process GO:0009203 199 0.014
regulation of proteolysis GO:0030162 164 0.014
cellular response to hormone stimulus GO:0032870 150 0.013
organelle assembly GO:0070925 177 0.013
rho protein signal transduction GO:0007266 32 0.013
negative regulation of intracellular signal transduction GO:1902532 167 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.013
lymphocyte proliferation GO:0046651 164 0.013
organophosphate biosynthetic process GO:0090407 122 0.013
regulation of ras protein signal transduction GO:0046578 114 0.013
purine nucleoside triphosphate catabolic process GO:0009146 203 0.013
tube formation GO:0035148 140 0.013
small molecule biosynthetic process GO:0044283 132 0.013
locomotory behavior GO:0007626 195 0.013
gtp catabolic process GO:0006184 143 0.013
cellular protein complex assembly GO:0043623 116 0.013
microtubule cytoskeleton organization GO:0000226 157 0.013
glycoprotein biosynthetic process GO:0009101 89 0.013
axon ensheathment GO:0008366 76 0.013
cofactor metabolic process GO:0051186 80 0.013
negative regulation of protein modification process GO:0031400 163 0.013
guanosine containing compound metabolic process GO:1901068 144 0.013
protein localization to nucleus GO:0034504 121 0.013
epithelial tube morphogenesis GO:0060562 303 0.013
engulfment of apoptotic cell GO:0043652 3 0.013
positive regulation of nfat protein import into nucleus GO:0051533 1 0.013
actin cytoskeleton organization GO:0030036 220 0.013
cellular response to cytokine stimulus GO:0071345 189 0.013
protein localization to plasma membrane GO:0072659 57 0.013
lipoprotein metabolic process GO:0042157 43 0.013
negative regulation of molecular function GO:0044092 258 0.013
peptidyl amino acid modification GO:0018193 336 0.013
protein ubiquitination GO:0016567 171 0.013
cellular component assembly involved in morphogenesis GO:0010927 139 0.013
gonad development GO:0008406 141 0.013
leukocyte proliferation GO:0070661 172 0.012
regulation of secretion by cell GO:1903530 249 0.012
purine ribonucleotide metabolic process GO:0009150 290 0.012
response to inorganic substance GO:0010035 96 0.012
muscle system process GO:0003012 141 0.012
positive regulation of protein transport GO:0051222 93 0.012
purine ribonucleotide catabolic process GO:0009154 208 0.012
positive regulation of programmed cell death GO:0043068 218 0.012
blood vessel morphogenesis GO:0048514 285 0.012
immune effector process GO:0002252 321 0.012
skeletal muscle organ development GO:0060538 163 0.012
hindbrain development GO:0030902 128 0.012
regulation of lymphocyte activation GO:0051249 240 0.012
modification dependent protein catabolic process GO:0019941 133 0.012
oocyte anterior posterior axis specification GO:0007314 2 0.012
cytokine production GO:0001816 319 0.012
protein secretion GO:0009306 111 0.012
blood circulation GO:0008015 195 0.012
response to epidermal growth factor GO:0070849 4 0.012
metal ion homeostasis GO:0055065 189 0.012
response to radiation GO:0009314 165 0.012
cellular ion homeostasis GO:0006873 165 0.012
angiogenesis GO:0001525 201 0.012
glycoprotein metabolic process GO:0009100 116 0.012
establishment of protein localization to membrane GO:0090150 54 0.012
nucleotide catabolic process GO:0009166 217 0.012
positive regulation of apoptotic process GO:0043065 217 0.012
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 12 0.012
cellular response to oxidative stress GO:0034599 76 0.012
regulation of vesicle mediated transport GO:0060627 139 0.012
response to growth factor GO:0070848 198 0.012
gland development GO:0048732 330 0.012
regulation of cell motility GO:2000145 236 0.012
response to organic cyclic compound GO:0014070 198 0.012
morphogenesis of embryonic epithelium GO:0016331 159 0.012
regulation of intracellular protein transport GO:0033157 82 0.012
mitochondrion transport along microtubule GO:0047497 3 0.012
regulation of kinase activity GO:0043549 249 0.012
defecation GO:0030421 1 0.012
epithelial cell proliferation GO:0050673 174 0.012
rna catabolic process GO:0006401 29 0.011
developmental maturation GO:0021700 193 0.011
cajal body organization GO:0030576 1 0.011
nucleoside monophosphate metabolic process GO:0009123 85 0.011
organelle localization GO:0051640 179 0.011
regulation of homeostatic process GO:0032844 182 0.011
neural tube formation GO:0001841 108 0.011
regulation of leukocyte proliferation GO:0070663 121 0.011
embryonic epithelial tube formation GO:0001838 130 0.011
sulfur compound biosynthetic process GO:0044272 37 0.011
urogenital system development GO:0001655 261 0.011
ribonucleoprotein complex disassembly GO:0032988 3 0.011
rhythmic process GO:0048511 174 0.011
nitrogen compound transport GO:0071705 271 0.011
glycosylation GO:0070085 62 0.011
sensory organ morphogenesis GO:0090596 242 0.011
hematopoietic progenitor cell differentiation GO:0002244 143 0.011
muscle cell differentiation GO:0042692 261 0.011
nucleoside triphosphate metabolic process GO:0009141 230 0.011
germ cell development GO:0007281 185 0.011
renal system development GO:0072001 225 0.011
regulation of cytokine production GO:0001817 266 0.011
spermatid development GO:0007286 108 0.011
cellular metal ion homeostasis GO:0006875 151 0.011
positive regulation of protein phosphorylation GO:0001934 242 0.011
response to peptide GO:1901652 136 0.011
regulation of metal ion transport GO:0010959 106 0.011
skeletal system development GO:0001501 356 0.011
epidermis development GO:0008544 187 0.011
proteasomal protein catabolic process GO:0010498 98 0.011
mrna metabolic process GO:0016071 84 0.011
cerebellum development GO:0021549 77 0.011
extrinsic apoptotic signaling pathway GO:0097191 126 0.011
innate immune response GO:0045087 157 0.011
negative regulation of organelle organization GO:0010639 90 0.011
interleukin 8 production GO:0032637 4 0.011
rna interference GO:0016246 2 0.011
plus end directed vesicle transport along microtubule GO:0072383 2 0.011
regulation of cytoplasmic transport GO:1903649 112 0.011
negative regulation of cell proliferation GO:0008285 296 0.011
multicellular organism growth GO:0035264 161 0.011
glycerolipid metabolic process GO:0046486 122 0.010
adult behavior GO:0030534 135 0.010
positive regulation of cell development GO:0010720 237 0.010
energy derivation by oxidation of organic compounds GO:0015980 77 0.010
lymphocyte differentiation GO:0030098 242 0.010
negative regulation of nervous system development GO:0051961 156 0.010
male genitalia morphogenesis GO:0048808 4 0.010
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.010
glycerophospholipid metabolic process GO:0006650 71 0.010
negative regulation of phosphorylation GO:0042326 166 0.010

Ide disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.020
central nervous system disease DOID:331 0 0.014
disease of metabolism DOID:0014667 0 0.013
inherited metabolic disorder DOID:655 0 0.013
sensory system disease DOID:0050155 0 0.013
eye and adnexa disease DOID:1492 0 0.013
immune system disease DOID:2914 0 0.013
neurodegenerative disease DOID:1289 0 0.012
eye disease DOID:5614 0 0.010