Mus musculus

0 known processes

Lrrc18

leucine rich repeat containing 18

(Aliases: 4930442L21Rik,MTLR1)

Lrrc18 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
immune effector process GO:0002252 321 0.157
spermatid differentiation GO:0048515 115 0.115
microtubule based movement GO:0007018 84 0.088
cation transport GO:0006812 399 0.086
regulation of ion transport GO:0043269 215 0.070
sequestering of calcium ion GO:0051208 18 0.069
sequestering of metal ion GO:0051238 19 0.064
cellular lipid metabolic process GO:0044255 323 0.064
membrane organization GO:0061024 245 0.060
activation of immune response GO:0002253 138 0.059
leukocyte mediated immunity GO:0002443 174 0.057
cation transmembrane transport GO:0098655 266 0.051
regulation of establishment of protein localization GO:0070201 181 0.051
regulation of organelle organization GO:0033043 289 0.049
exocytosis GO:0006887 121 0.047
calcium ion transport GO:0006816 159 0.046
metal ion homeostasis GO:0055065 189 0.045
immune response regulating signaling pathway GO:0002764 125 0.043
cellular amino acid metabolic process GO:0006520 103 0.041
regulation of cellular ketone metabolic process GO:0010565 66 0.041
cellular ion homeostasis GO:0006873 165 0.040
male gamete generation GO:0048232 285 0.040
wnt signaling pathway GO:0016055 188 0.040
cellular chemical homeostasis GO:0055082 215 0.039
protein secretion GO:0009306 111 0.039
t cell activation GO:0042110 289 0.039
regulation of homeostatic process GO:0032844 182 0.038
inorganic cation transmembrane transport GO:0098662 207 0.037
mapk cascade GO:0000165 281 0.037
homeostasis of number of cells GO:0048872 210 0.036
regulation of cell activation GO:0050865 289 0.036
sensory perception GO:0007600 245 0.035
inflammatory response GO:0006954 244 0.035
regulation of leukocyte mediated immunity GO:0002703 104 0.033
regulation of intracellular transport GO:0032386 159 0.033
divalent inorganic cation transport GO:0072511 178 0.032
immune response activating signal transduction GO:0002757 116 0.032
regulation of lymphocyte activation GO:0051249 240 0.031
synaptic transmission GO:0007268 329 0.031
reactive oxygen species metabolic process GO:0072593 84 0.031
regulation of metal ion transport GO:0010959 106 0.031
nucleoside phosphate metabolic process GO:0006753 338 0.031
regulation of cytokine production GO:0001817 266 0.031
microtubule based process GO:0007017 236 0.030
regulation of cellular component size GO:0032535 121 0.030
lymphocyte mediated immunity GO:0002449 139 0.030
nucleotide metabolic process GO:0009117 332 0.030
innate immune response activating signal transduction GO:0002758 50 0.030
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.029
cytokine production GO:0001816 319 0.029
regulation of protein localization GO:0032880 231 0.029
positive regulation of protein modification process GO:0031401 299 0.028
purine nucleotide metabolic process GO:0006163 302 0.028
regulation of defense response GO:0031347 233 0.028
regulation of cytoplasmic transport GO:1903649 112 0.028
germ cell development GO:0007281 185 0.028
regulation of ion transmembrane transporter activity GO:0032412 54 0.028
spermatid development GO:0007286 108 0.027
adaptive immune response GO:0002250 155 0.027
cellular protein complex assembly GO:0043623 116 0.027
ribonucleoside metabolic process GO:0009119 245 0.027
cellular homeostasis GO:0019725 240 0.027
g protein coupled receptor signaling pathway GO:0007186 243 0.027
regulation of cellular amine metabolic process GO:0033238 20 0.027
nucleobase containing small molecule metabolic process GO:0055086 352 0.027
cellular ketone metabolic process GO:0042180 84 0.027
regulation of inflammatory response GO:0050727 147 0.026
activation of mapk activity involved in innate immune response GO:0035419 2 0.026
carbohydrate derivative biosynthetic process GO:1901137 183 0.026
ribose phosphate metabolic process GO:0019693 291 0.026
negative regulation of intracellular signal transduction GO:1902532 167 0.026
cellular metal ion homeostasis GO:0006875 151 0.026
multicellular organismal homeostasis GO:0048871 164 0.025
regulation of ion transmembrane transport GO:0034765 119 0.025
sperm motility GO:0030317 47 0.025
negative regulation of homeostatic process GO:0032845 71 0.024
alcohol metabolic process GO:0006066 116 0.024
peptidyl amino acid modification GO:0018193 336 0.024
organelle localization GO:0051640 179 0.024
organic hydroxy compound metabolic process GO:1901615 203 0.024
negative regulation of molecular function GO:0044092 258 0.024
positive regulation of homeostatic process GO:0032846 64 0.024
regulation of transmembrane transport GO:0034762 128 0.023
cellular divalent inorganic cation homeostasis GO:0072503 127 0.023
carbohydrate metabolic process GO:0005975 230 0.023
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.023
gland development GO:0048732 330 0.023
activation of innate immune response GO:0002218 56 0.023
purine nucleoside metabolic process GO:0042278 241 0.023
amine metabolic process GO:0009308 45 0.023
inorganic ion transmembrane transport GO:0098660 234 0.023
purine ribonucleoside metabolic process GO:0046128 241 0.022
positive regulation of protein phosphorylation GO:0001934 242 0.022
positive regulation of kinase activity GO:0033674 155 0.022
glycoprotein metabolic process GO:0009100 116 0.022
regulation of neuron projection development GO:0010975 169 0.022
b cell activation GO:0042113 161 0.022
purine containing compound metabolic process GO:0072521 311 0.022
leukocyte migration GO:0050900 124 0.022
spermatogenesis GO:0007283 284 0.022
myeloid cell differentiation GO:0030099 233 0.022
innate immune response GO:0045087 157 0.022
regulation of vesicle mediated transport GO:0060627 139 0.021
divalent metal ion transport GO:0070838 172 0.021
cytoplasmic transport GO:0016482 234 0.021
regulation of wnt signaling pathway GO:0030111 123 0.021
cell type specific apoptotic process GO:0097285 268 0.021
protein modification by small protein conjugation GO:0032446 187 0.021
actin cytoskeleton organization GO:0030036 220 0.021
positive regulation of organelle organization GO:0010638 128 0.021
cell activation involved in immune response GO:0002263 126 0.021
macromolecule catabolic process GO:0009057 281 0.021
negative regulation of immune system process GO:0002683 209 0.020
b cell differentiation GO:0030183 78 0.020
positive regulation of programmed cell death GO:0043068 218 0.020
lymphocyte proliferation GO:0046651 164 0.020
regulation of protein transport GO:0051223 163 0.020
regulation of lymphocyte mediated immunity GO:0002706 84 0.020
phospholipid metabolic process GO:0006644 87 0.020
leukocyte proliferation GO:0070661 172 0.020
ribonucleotide metabolic process GO:0009259 291 0.020
neuron death GO:0070997 154 0.019
t cell proliferation GO:0042098 120 0.019
nuclear division GO:0000280 158 0.019
embryonic organ morphogenesis GO:0048562 276 0.019
endomembrane system organization GO:0010256 147 0.019
ribonucleoside triphosphate metabolic process GO:0009199 220 0.019
dna metabolic process GO:0006259 303 0.019
cellular amine metabolic process GO:0044106 44 0.019
protein catabolic process GO:0030163 221 0.019
divalent inorganic cation homeostasis GO:0072507 138 0.019
response to lipopolysaccharide GO:0032496 128 0.019
leukocyte differentiation GO:0002521 342 0.019
action potential GO:0001508 78 0.018
regulation of reactive oxygen species metabolic process GO:2000377 40 0.018
regulation of mapk cascade GO:0043408 248 0.018
lipid transport GO:0006869 98 0.018
regulation of t cell activation GO:0050863 170 0.018
i kappab kinase nf kappab signaling GO:0007249 85 0.018
regulation of adaptive immune response GO:0002819 90 0.018
calcium ion homeostasis GO:0055074 127 0.018
positive regulation of mapk cascade GO:0043410 170 0.018
endocytosis GO:0006897 168 0.018
positive regulation of ion transport GO:0043270 65 0.018
regulation of cytoskeleton organization GO:0051493 122 0.018
cellular component assembly involved in morphogenesis GO:0010927 139 0.017
small molecule biosynthetic process GO:0044283 132 0.017
regulation of secretion GO:0051046 274 0.017
regulation of cellular amino acid metabolic process GO:0006521 5 0.017
regulation of binding GO:0051098 111 0.017
negative regulation of cell proliferation GO:0008285 296 0.017
purine ribonucleotide metabolic process GO:0009150 290 0.017
positive regulation of secretion GO:0051047 130 0.016
regulation of neuron death GO:1901214 134 0.016
tissue homeostasis GO:0001894 115 0.016
cellular calcium ion homeostasis GO:0006874 119 0.016
embryonic placenta development GO:0001892 98 0.016
small gtpase mediated signal transduction GO:0007264 97 0.016
ribonucleotide catabolic process GO:0009261 208 0.016
cellular protein catabolic process GO:0044257 155 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.016
locomotory behavior GO:0007626 195 0.016
regulation of immunoglobulin mediated immune response GO:0002889 37 0.016
lymphocyte differentiation GO:0030098 242 0.016
positive regulation of innate immune response GO:0045089 80 0.016
organonitrogen compound biosynthetic process GO:1901566 192 0.016
toll like receptor signaling pathway GO:0002224 38 0.016
protein modification by small protein conjugation or removal GO:0070647 207 0.016
intracellular receptor signaling pathway GO:0030522 74 0.016
regulation of neurotransmitter levels GO:0001505 87 0.016
regulation of canonical wnt signaling pathway GO:0060828 82 0.016
neurotransmitter transport GO:0006836 76 0.016
actin filament polymerization GO:0030041 44 0.015
regulation of membrane potential GO:0042391 192 0.015
regulation of actin filament based process GO:0032970 99 0.015
positive regulation of transferase activity GO:0051347 167 0.015
organelle assembly GO:0070925 177 0.015
organic cyclic compound catabolic process GO:1901361 295 0.015
negative regulation of cell activation GO:0050866 111 0.015
anatomical structure homeostasis GO:0060249 145 0.015
regulation of cellular component biogenesis GO:0044087 181 0.015
negative regulation of neuron apoptotic process GO:0043524 92 0.015
regulation of secretion by cell GO:1903530 249 0.015
cellular response to biotic stimulus GO:0071216 92 0.015
regulation of proteolysis GO:0030162 164 0.015
anion transport GO:0006820 177 0.015
leukocyte activation involved in immune response GO:0002366 126 0.015
positive regulation of defense response GO:0031349 124 0.015
response to light stimulus GO:0009416 135 0.015
epithelial cell development GO:0002064 159 0.015
muscle system process GO:0003012 141 0.015
regulation of leukocyte differentiation GO:1902105 159 0.015
atp metabolic process GO:0046034 75 0.015
regulation of protein complex assembly GO:0043254 83 0.015
cilium morphogenesis GO:0060271 102 0.015
cation homeostasis GO:0055080 212 0.015
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.015
glycosyl compound metabolic process GO:1901657 246 0.015
regulation of leukocyte proliferation GO:0070663 121 0.015
cytokine biosynthetic process GO:0042089 68 0.014
protein maturation GO:0051604 176 0.014
neuron neuron synaptic transmission GO:0007270 69 0.014
peptidyl serine modification GO:0018209 83 0.014
regulation of striated muscle cell differentiation GO:0051153 81 0.014
purine nucleoside triphosphate catabolic process GO:0009146 203 0.014
positive regulation of immune effector process GO:0002699 107 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.014
heterocycle catabolic process GO:0046700 280 0.014
microtubule cytoskeleton organization GO:0000226 157 0.014
regulation of calcium ion transport into cytosol GO:0010522 31 0.014
rho protein signal transduction GO:0007266 32 0.014
b cell mediated immunity GO:0019724 71 0.014
nucleoside metabolic process GO:0009116 246 0.014
fertilization GO:0009566 127 0.014
adult behavior GO:0030534 135 0.014
glycerolipid metabolic process GO:0046486 122 0.014
regulation of neuron apoptotic process GO:0043523 122 0.014
regulation of feeding behavior GO:0060259 3 0.014
regulation of actin nucleation GO:0051125 4 0.014
aromatic compound catabolic process GO:0019439 286 0.014
cell adhesion GO:0007155 329 0.014
actin polymerization or depolymerization GO:0008154 54 0.014
canonical wnt signaling pathway GO:0060070 130 0.013
organophosphate catabolic process GO:0046434 232 0.013
mesodermal cell migration GO:0008078 4 0.013
regulation of steroid hormone biosynthetic process GO:0090030 4 0.013
positive regulation of hydrolase activity GO:0051345 148 0.013
cytosolic calcium ion transport GO:0060401 48 0.013
regulation of ion homeostasis GO:2000021 64 0.013
protein polymerization GO:0051258 57 0.013
purine nucleoside catabolic process GO:0006152 205 0.013
plasma membrane organization GO:0007009 90 0.013
tumor necrosis factor ligand superfamily member 11 production GO:0072535 1 0.013
protein glycosylation GO:0006486 55 0.013
actin filament organization GO:0007015 113 0.013
muscle tissue development GO:0060537 308 0.013
purine nucleotide catabolic process GO:0006195 211 0.013
negative regulation of t cell proliferation GO:0042130 38 0.013
protein ubiquitination GO:0016567 171 0.013
transmembrane transport GO:0055085 412 0.013
protein localization to membrane GO:0072657 108 0.013
purine containing compound catabolic process GO:0072523 213 0.013
carbohydrate derivative catabolic process GO:1901136 231 0.013
immunoglobulin mediated immune response GO:0016064 69 0.013
regulation of protein kinase activity GO:0045859 232 0.013
posttranscriptional regulation of gene expression GO:0010608 155 0.013
glycoprotein biosynthetic process GO:0009101 89 0.013
regulation of calcium ion transport GO:0051924 69 0.013
calcium ion transmembrane transport GO:0070588 85 0.012
response to molecule of bacterial origin GO:0002237 143 0.012
response to radiation GO:0009314 165 0.012
purine ribonucleoside catabolic process GO:0046130 205 0.012
meiotic nuclear division GO:0007126 115 0.012
pma inducible membrane protein ectodomain proteolysis GO:0051088 1 0.012
regulation of eosinophil migration GO:2000416 2 0.012
cellular response to lipid GO:0071396 145 0.012
urogenital system development GO:0001655 261 0.012
organophosphate biosynthetic process GO:0090407 122 0.012
cellular nitrogen compound catabolic process GO:0044270 280 0.012
regulation of response to wounding GO:1903034 189 0.012
regulation of t cell proliferation GO:0042129 92 0.012
nucleoside triphosphate catabolic process GO:0009143 205 0.012
positive regulation of membrane protein ectodomain proteolysis GO:0051044 3 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.012
nucleotide catabolic process GO:0009166 217 0.012
organic hydroxy compound transport GO:0015850 93 0.012
nucleoside triphosphate metabolic process GO:0009141 230 0.012
glycosylation GO:0070085 62 0.012
positive regulation of protein catabolic process GO:0045732 60 0.012
cellularization GO:0007349 1 0.012
glycosyl compound catabolic process GO:1901658 206 0.012
humoral immune response GO:0006959 57 0.012
ribonucleoside triphosphate catabolic process GO:0009203 199 0.012
kidney development GO:0001822 213 0.012
neuron apoptotic process GO:0051402 142 0.012
purine ribonucleotide catabolic process GO:0009154 208 0.012
vesicle organization GO:0016050 60 0.012
ion transmembrane transport GO:0034220 361 0.012
protein acylation GO:0043543 64 0.012
regulation of body fluid levels GO:0050878 162 0.012
regulation of cellular catabolic process GO:0031329 242 0.011
b cell activation involved in immune response GO:0002312 50 0.011
purine nucleoside triphosphate metabolic process GO:0009144 226 0.011
response to organic cyclic compound GO:0014070 198 0.011
negative regulation of nlrp3 inflammasome complex assembly GO:1900226 2 0.011
regulation of protein catabolic process GO:0042176 108 0.011
regulation of innate immune response GO:0045088 91 0.011
positive regulation of apoptotic process GO:0043065 217 0.011
hematopoietic progenitor cell differentiation GO:0002244 143 0.011
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.011
inner ear receptor cell development GO:0060119 39 0.011
lipid biosynthetic process GO:0008610 179 0.011
ubiquitin dependent protein catabolic process GO:0006511 129 0.011
cilium assembly GO:0042384 81 0.011
muscle cell differentiation GO:0042692 261 0.011
negative regulation of defense response GO:0031348 77 0.011
modification dependent protein catabolic process GO:0019941 133 0.011
axonogenesis GO:0007409 274 0.011
oocyte axis specification GO:0007309 2 0.011
organelle fission GO:0048285 170 0.011
sensory organ morphogenesis GO:0090596 242 0.011
myeloid cell homeostasis GO:0002262 114 0.011
digestive system development GO:0055123 200 0.011
regulation of cell adhesion GO:0030155 154 0.011
compound eye development GO:0048749 1 0.011
negative regulation of lymphocyte proliferation GO:0050672 45 0.011
extracellular matrix dependent thymocyte migration GO:0072680 1 0.011
lymphocyte activation involved in immune response GO:0002285 93 0.011
digestive tract morphogenesis GO:0048546 147 0.011
monocarboxylic acid metabolic process GO:0032787 191 0.011
multicellular organism growth GO:0035264 161 0.011
skin development GO:0043588 220 0.011
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.011
mechanoreceptor differentiation GO:0042490 67 0.011
multicellular organismal signaling GO:0035637 91 0.011
meiotic cell cycle GO:0051321 122 0.011
negative regulation of immune effector process GO:0002698 55 0.011
positive regulation of growth GO:0045927 104 0.011
regionalization GO:0003002 337 0.011
maintenance of location GO:0051235 89 0.010
negative regulation of cell cycle GO:0045786 123 0.010
establishment of synaptic vesicle localization GO:0097480 57 0.010
negative regulation of protein transport GO:0051224 46 0.010
fibronectin dependent thymocyte migration GO:0072681 1 0.010
protein oligomerization GO:0051259 67 0.010
establishment of organelle localization GO:0051656 122 0.010
negative regulation of cellular protein metabolic process GO:0032269 247 0.010
sulfur compound metabolic process GO:0006790 100 0.010
positive regulation of cellular amine metabolic process GO:0033240 5 0.010
positive regulation of cell death GO:0010942 224 0.010
translation GO:0006412 93 0.010
intrinsic apoptotic signaling pathway GO:0097193 132 0.010
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.010
stem cell differentiation GO:0048863 268 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.010
regulation of membrane protein ectodomain proteolysis GO:0051043 3 0.010
establishment of vesicle localization GO:0051650 81 0.010
synapse organization GO:0050808 125 0.010
inner ear receptor cell differentiation GO:0060113 61 0.010
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.010

Lrrc18 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
retinal disease DOID:5679 0 0.021
sensory system disease DOID:0050155 0 0.021
disease of anatomical entity DOID:7 0 0.021
eye and adnexa disease DOID:1492 0 0.021
nervous system disease DOID:863 0 0.021
eye disease DOID:5614 0 0.021
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
organ system cancer DOID:0050686 0 0.014