Mus musculus

133 known processes

Pdk4

pyruvate dehydrogenase kinase, isoenzyme 4

(Aliases: AV005916)

Pdk4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxidation reduction process GO:0055114 342 0.208
cofactor metabolic process GO:0051186 80 0.144
monocarboxylic acid metabolic process GO:0032787 191 0.134
long chain fatty acid import GO:0044539 2 0.126
cellular lipid metabolic process GO:0044255 323 0.125
cellular ketone metabolic process GO:0042180 84 0.122
cellular lipid catabolic process GO:0044242 52 0.117
cellular amine metabolic process GO:0044106 44 0.117
fatty acid metabolic process GO:0006631 121 0.116
amine metabolic process GO:0009308 45 0.113
cellular amino acid metabolic process GO:0006520 103 0.112
transmembrane transport GO:0055085 412 0.086
small molecule catabolic process GO:0044282 71 0.085
lipid catabolic process GO:0016042 69 0.082
cation transport GO:0006812 399 0.082
regulation of cellular amine metabolic process GO:0033238 20 0.079
carbohydrate metabolic process GO:0005975 230 0.076
organic anion transport GO:0015711 137 0.070
cellular response to organonitrogen compound GO:0071417 145 0.069
negative regulation of molecular function GO:0044092 258 0.066
organonitrogen compound catabolic process GO:1901565 264 0.065
lipid biosynthetic process GO:0008610 179 0.065
regulation of cellular ketone metabolic process GO:0010565 66 0.064
response to oxidative stress GO:0006979 123 0.064
acylglycerol metabolic process GO:0006639 55 0.063
response to organonitrogen compound GO:0010243 246 0.063
negative regulation of protein metabolic process GO:0051248 282 0.063
negative regulation of phosphorus metabolic process GO:0010563 184 0.062
sterol homeostasis GO:0055092 45 0.062
lipid transport GO:0006869 98 0.061
glycerolipid metabolic process GO:0046486 122 0.060
lipid modification GO:0030258 65 0.060
regulation of cellular amino acid metabolic process GO:0006521 5 0.058
organic hydroxy compound metabolic process GO:1901615 203 0.056
nucleoside phosphate metabolic process GO:0006753 338 0.055
regulation of fatty acid oxidation GO:0046320 10 0.052
anion transport GO:0006820 177 0.052
ion transmembrane transport GO:0034220 361 0.052
triglyceride metabolic process GO:0006641 51 0.051
nucleotide metabolic process GO:0009117 332 0.049
neutral lipid metabolic process GO:0006638 57 0.048
cholesterol homeostasis GO:0042632 44 0.048
maintenance of location GO:0051235 89 0.048
lipid homeostasis GO:0055088 63 0.048
cytokine production GO:0001816 319 0.044
response to hypoxia GO:0001666 58 0.043
lipid oxidation GO:0034440 29 0.043
response to organic cyclic compound GO:0014070 198 0.043
pyridine nucleotide catabolic process GO:0019364 3 0.042
peptidyl amino acid modification GO:0018193 336 0.042
nucleobase containing small molecule metabolic process GO:0055086 352 0.042
response to oxygen levels GO:0070482 62 0.042
cation transmembrane transport GO:0098655 266 0.042
heterocycle catabolic process GO:0046700 280 0.041
negative regulation of protein phosphorylation GO:0001933 126 0.041
cellular nitrogen compound catabolic process GO:0044270 280 0.040
negative regulation of cellular protein metabolic process GO:0032269 247 0.039
cellular response to oxidative stress GO:0034599 76 0.039
lipid localization GO:0010876 126 0.039
reactive oxygen species metabolic process GO:0072593 84 0.039
positive regulation of cell death GO:0010942 224 0.038
negative regulation of phosphorylation GO:0042326 166 0.038
regulation of apoptotic signaling pathway GO:2001233 197 0.038
cellular response to hormone stimulus GO:0032870 150 0.037
fat cell differentiation GO:0045444 160 0.037
organic acid transport GO:0015849 101 0.037
organic cyclic compound catabolic process GO:1901361 295 0.036
inorganic cation transmembrane transport GO:0098662 207 0.036
carboxylic acid transport GO:0046942 100 0.036
negative regulation of phosphate metabolic process GO:0045936 184 0.036
apoptotic signaling pathway GO:0097190 306 0.036
muscle system process GO:0003012 141 0.036
organophosphate catabolic process GO:0046434 232 0.036
negative regulation of protein modification process GO:0031400 163 0.036
aromatic compound catabolic process GO:0019439 286 0.035
response to peptide GO:1901652 136 0.035
multicellular organismal signaling GO:0035637 91 0.034
positive regulation of cellular amine metabolic process GO:0033240 5 0.034
regulation of membrane potential GO:0042391 192 0.034
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.034
fatty acid oxidation GO:0019395 28 0.034
regulation of cellular catabolic process GO:0031329 242 0.033
glycerolipid biosynthetic process GO:0045017 50 0.033
response to radiation GO:0009314 165 0.032
response to lipopolysaccharide GO:0032496 128 0.032
macromolecule catabolic process GO:0009057 281 0.031
positive regulation of apoptotic process GO:0043065 217 0.031
brown fat cell differentiation GO:0050873 36 0.031
regulation of transferase activity GO:0051338 263 0.031
energy derivation by oxidation of organic compounds GO:0015980 77 0.031
muscle tissue development GO:0060537 308 0.031
circulatory system process GO:0003013 197 0.030
cellular ion homeostasis GO:0006873 165 0.030
ribonucleotide metabolic process GO:0009259 291 0.030
response to peptide hormone GO:0043434 127 0.030
response to inorganic substance GO:0010035 96 0.029
ribose phosphate metabolic process GO:0019693 291 0.029
alcohol metabolic process GO:0006066 116 0.029
purine containing compound metabolic process GO:0072521 311 0.029
regulation of lipid metabolic process GO:0019216 118 0.029
regulation of hydrolase activity GO:0051336 246 0.029
negative regulation of transferase activity GO:0051348 85 0.029
g protein coupled receptor signaling pathway GO:0007186 243 0.029
heart contraction GO:0060047 93 0.028
cellular homeostasis GO:0019725 240 0.028
response to decreased oxygen levels GO:0036293 59 0.028
cholesterol metabolic process GO:0008203 56 0.028
organophosphate biosynthetic process GO:0090407 122 0.028
coenzyme metabolic process GO:0006732 52 0.028
inflammatory response GO:0006954 244 0.028
camera type eye development GO:0043010 266 0.027
blood circulation GO:0008015 195 0.027
purine nucleotide metabolic process GO:0006163 302 0.027
response to drug GO:0042493 75 0.027
negative regulation of intracellular signal transduction GO:1902532 167 0.027
regulation of hormone levels GO:0010817 211 0.026
regulation of leukocyte differentiation GO:1902105 159 0.026
carboxylic acid catabolic process GO:0046395 51 0.026
regulation of kinase activity GO:0043549 249 0.026
glycerophospholipid metabolic process GO:0006650 71 0.026
sterol metabolic process GO:0016125 58 0.026
regulation of system process GO:0044057 200 0.026
regulation of cytokine production GO:0001817 266 0.026
cholesterol storage GO:0010878 4 0.026
regulation of homeostatic process GO:0032844 182 0.025
purine containing compound catabolic process GO:0072523 213 0.025
response to molecule of bacterial origin GO:0002237 143 0.025
nucleotide catabolic process GO:0009166 217 0.025
steroid metabolic process GO:0008202 119 0.025
monocarboxylic acid transport GO:0015718 44 0.025
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.025
intrinsic apoptotic signaling pathway GO:0097193 132 0.025
cell adhesion GO:0007155 329 0.025
positive regulation of programmed cell death GO:0043068 218 0.024
t cell activation GO:0042110 289 0.024
negative regulation of kinase activity GO:0033673 81 0.024
skeletal muscle organ development GO:0060538 163 0.024
positive regulation of protein modification process GO:0031401 299 0.024
striated muscle tissue development GO:0014706 293 0.024
sulfur compound metabolic process GO:0006790 100 0.024
protein maturation GO:0051604 176 0.024
cation homeostasis GO:0055080 212 0.024
second messenger mediated signaling GO:0019932 73 0.024
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.024
generation of precursor metabolites and energy GO:0006091 103 0.024
monosaccharide metabolic process GO:0005996 106 0.023
regulation of mapk cascade GO:0043408 248 0.023
regulation of ion transmembrane transport GO:0034765 119 0.023
regulation of ion transport GO:0043269 215 0.023
long chain fatty acid metabolic process GO:0001676 26 0.023
monocarboxylic acid catabolic process GO:0072329 27 0.022
multicellular organismal homeostasis GO:0048871 164 0.022
cellular response to peptide GO:1901653 92 0.022
myeloid cell differentiation GO:0030099 233 0.022
response to acid chemical GO:0001101 111 0.022
spermatogenesis GO:0007283 284 0.022
negative regulation of hydrolase activity GO:0051346 71 0.022
response to insulin GO:0032868 100 0.022
regulation of lipid biosynthetic process GO:0046890 54 0.022
regulation of phospholipid biosynthetic process GO:0071071 3 0.022
protein catabolic process GO:0030163 221 0.022
regulation of cell projection organization GO:0031344 206 0.022
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.022
isoprenoid metabolic process GO:0006720 29 0.022
regulation of cell activation GO:0050865 289 0.021
regulation of protein serine threonine kinase activity GO:0071900 157 0.021
organonitrogen compound biosynthetic process GO:1901566 192 0.021
purine nucleoside triphosphate metabolic process GO:0009144 226 0.021
mitochondrion organization GO:0007005 134 0.021
purine ribonucleotide metabolic process GO:0009150 290 0.021
membrane organization GO:0061024 245 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.021
nucleoside phosphate catabolic process GO:1901292 222 0.021
carbohydrate derivative biosynthetic process GO:1901137 183 0.021
blood vessel morphogenesis GO:0048514 285 0.021
glycosyl compound metabolic process GO:1901657 246 0.021
cellular carbohydrate metabolic process GO:0044262 119 0.021
hexose metabolic process GO:0019318 98 0.021
response to steroid hormone GO:0048545 56 0.021
cellular chemical homeostasis GO:0055082 215 0.021
regulation of anatomical structure size GO:0090066 178 0.021
long chain fatty acid transport GO:0015909 15 0.021
ribonucleoside metabolic process GO:0009119 245 0.021
negative regulation of cellular amine metabolic process GO:0033239 1 0.021
protein processing GO:0016485 163 0.020
ribonucleotide catabolic process GO:0009261 208 0.020
regulation of establishment of protein localization GO:0070201 181 0.020
positive regulation of cell development GO:0010720 237 0.020
response to nutrient levels GO:0031667 109 0.020
male gamete generation GO:0048232 285 0.020
forebrain development GO:0030900 302 0.020
nitrogen compound transport GO:0071705 271 0.020
nucleoside metabolic process GO:0009116 246 0.020
muscle contraction GO:0006936 101 0.020
nucleoside triphosphate metabolic process GO:0009141 230 0.020
cell type specific apoptotic process GO:0097285 268 0.020
regulation of neuron differentiation GO:0045664 281 0.020
muscle cell differentiation GO:0042692 261 0.020
diterpenoid metabolic process GO:0016101 24 0.020
locomotory behavior GO:0007626 195 0.019
negative regulation of phospholipase activity GO:0010519 4 0.019
immune effector process GO:0002252 321 0.019
purine ribonucleotide catabolic process GO:0009154 208 0.019
lipid storage GO:0019915 36 0.019
regulation of cell cycle GO:0051726 281 0.019
ribonucleoside triphosphate metabolic process GO:0009199 220 0.019
inorganic ion transmembrane transport GO:0098660 234 0.019
cellular response to biotic stimulus GO:0071216 92 0.019
purine nucleoside metabolic process GO:0042278 241 0.019
nucleoside catabolic process GO:0009164 206 0.019
multi multicellular organism process GO:0044706 109 0.019
cytoplasmic transport GO:0016482 234 0.019
positive regulation of fatty acid oxidation GO:0046321 4 0.019
regulation of carbohydrate metabolic process GO:0006109 75 0.019
protein modification by small protein conjugation or removal GO:0070647 207 0.019
neuronal action potential GO:0019228 54 0.019
positive regulation of macrophage derived foam cell differentiation GO:0010744 4 0.019
heart process GO:0003015 94 0.019
monocarboxylic acid biosynthetic process GO:0072330 61 0.018
regulation of blood pressure GO:0008217 93 0.018
glucose metabolic process GO:0006006 92 0.018
small gtpase mediated signal transduction GO:0007264 97 0.018
protein oligomerization GO:0051259 67 0.018
homeostasis of number of cells GO:0048872 210 0.018
response to light stimulus GO:0009416 135 0.018
innate immune response GO:0045087 157 0.018
very long chain fatty acid catabolic process GO:0042760 2 0.018
purine nucleoside catabolic process GO:0006152 205 0.018
phospholipid metabolic process GO:0006644 87 0.018
cellular macromolecule catabolic process GO:0044265 206 0.018
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 4 0.018
regulation of defense response GO:0031347 233 0.018
regulation of triglyceride biosynthetic process GO:0010866 10 0.018
leukocyte differentiation GO:0002521 342 0.017
cellular response to peptide hormone stimulus GO:0071375 92 0.017
divalent metal ion transport GO:0070838 172 0.017
protein localization to organelle GO:0033365 185 0.017
regulation of organelle organization GO:0033043 289 0.017
protein localization to nucleus GO:0034504 121 0.017
organic acid catabolic process GO:0016054 51 0.017
purine ribonucleoside catabolic process GO:0046130 205 0.017
anion transmembrane transport GO:0098656 71 0.017
purine ribonucleoside metabolic process GO:0046128 241 0.017
cellular response to insulin stimulus GO:0032869 78 0.017
cofactor catabolic process GO:0051187 6 0.017
regulation of phosphatidylcholine catabolic process GO:0010899 2 0.017
developmental growth involved in morphogenesis GO:0060560 138 0.017
ras protein signal transduction GO:0007265 77 0.017
cellular biogenic amine metabolic process GO:0006576 28 0.017
metal ion homeostasis GO:0055065 189 0.017
regulation of glucose metabolic process GO:0010906 60 0.016
sodium ion transport GO:0006814 73 0.016
purine nucleotide catabolic process GO:0006195 211 0.016
retinoid metabolic process GO:0001523 24 0.016
divalent inorganic cation homeostasis GO:0072507 138 0.016
coenzyme catabolic process GO:0009109 5 0.016
regulation of protein kinase activity GO:0045859 232 0.016
negative regulation of apoptotic signaling pathway GO:2001234 104 0.016
cellular response to organic cyclic compound GO:0071407 87 0.016
divalent inorganic cation transport GO:0072511 178 0.016
calcium ion transport GO:0006816 159 0.016
mapk cascade GO:0000165 281 0.016
protein modification by small protein conjugation GO:0032446 187 0.016
regulation of peptidase activity GO:0052547 96 0.016
telencephalon development GO:0021537 186 0.016
anatomical structure homeostasis GO:0060249 145 0.016
carbohydrate biosynthetic process GO:0016051 74 0.016
Mouse
ribonucleoside triphosphate catabolic process GO:0009203 199 0.016
ribonucleoside catabolic process GO:0042454 206 0.016
fat soluble vitamin biosynthetic process GO:0042362 4 0.016
reactive nitrogen species metabolic process GO:2001057 0 0.015
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.015
cellular response to dna damage stimulus GO:0006974 207 0.015
regulation of cellular response to stress GO:0080135 159 0.015
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.015
regulation of phosphatidylcholine biosynthetic process GO:2001245 2 0.015
cellular response to cytokine stimulus GO:0071345 189 0.015
carbohydrate derivative catabolic process GO:1901136 231 0.015
actin filament organization GO:0007015 113 0.015
ossification GO:0001503 216 0.015
endomembrane system organization GO:0010256 147 0.015
regulation of secretion GO:0051046 274 0.015
multicellular organism growth GO:0035264 161 0.015
regulation of protein transport GO:0051223 163 0.015
regulation of inflammatory response GO:0050727 147 0.015
actin cytoskeleton organization GO:0030036 220 0.015
action potential GO:0001508 78 0.015
regulation of cell motility GO:2000145 236 0.015
regulation of protein localization GO:0032880 231 0.015
organic acid biosynthetic process GO:0016053 86 0.015
regulation of response to wounding GO:1903034 189 0.015
regulation of muscle system process GO:0090257 80 0.015
kidney development GO:0001822 213 0.015
sensory perception GO:0007600 245 0.015
regulation of lymphocyte activation GO:0051249 240 0.015
urogenital system development GO:0001655 261 0.015
sensory organ morphogenesis GO:0090596 242 0.014
positive regulation of cytokine production GO:0001819 174 0.014
retina development in camera type eye GO:0060041 119 0.014
terpenoid metabolic process GO:0006721 25 0.014
purine nucleoside triphosphate catabolic process GO:0009146 203 0.014
circadian regulation of gene expression GO:0032922 48 0.014
posttranscriptional regulation of gene expression GO:0010608 155 0.014
axonogenesis GO:0007409 274 0.014
cellular response to molecule of bacterial origin GO:0071219 83 0.014
ribonucleoside monophosphate metabolic process GO:0009161 80 0.014
striated muscle contraction GO:0006941 45 0.014
fatty acid transport GO:0015908 28 0.014
triglyceride biosynthetic process GO:0019432 17 0.014
positive regulation of protein phosphorylation GO:0001934 242 0.014
negative regulation of immune system process GO:0002683 209 0.014
actin filament based movement GO:0030048 23 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.014
regulation of transmembrane transport GO:0034762 128 0.014
protein ubiquitination GO:0016567 171 0.014
regulation of proteolysis GO:0030162 164 0.014
regulation of cell growth GO:0001558 91 0.014
positive regulation of growth GO:0045927 104 0.014
cellular response to lipid GO:0071396 145 0.014
cardiac muscle contraction GO:0060048 32 0.014
regulation of reactive oxygen species metabolic process GO:2000377 40 0.014
purine nucleoside monophosphate metabolic process GO:0009126 81 0.014
organic hydroxy compound transport GO:0015850 93 0.014
potassium ion transport GO:0006813 52 0.014
glycoprotein metabolic process GO:0009100 116 0.014
hexose transport GO:0008645 56 0.014
respiratory system development GO:0060541 190 0.014
response to mineralocorticoid GO:0051385 1 0.014
response to vitamin a GO:0033189 1 0.014
cellular response to lipopolysaccharide GO:0071222 77 0.014
dephosphorylation GO:0016311 129 0.013
microtubule based process GO:0007017 236 0.013
epithelial cell development GO:0002064 159 0.013
small molecule biosynthetic process GO:0044283 132 0.013
response to extracellular stimulus GO:0009991 127 0.013
defense response to other organism GO:0098542 197 0.013
regulation of cellular component biogenesis GO:0044087 181 0.013
glycerolipid catabolic process GO:0046503 16 0.013
positive regulation of nervous system development GO:0051962 221 0.013
monosaccharide transport GO:0015749 58 0.013
rna interference GO:0016246 2 0.013
cellular response to inorganic substance GO:0071241 37 0.013
nucleocytoplasmic transport GO:0006913 139 0.013
transmission of nerve impulse GO:0019226 76 0.013
cellular amide metabolic process GO:0043603 58 0.013
embryonic organ morphogenesis GO:0048562 276 0.013
cellular response to growth factor stimulus GO:0071363 197 0.013
cellular calcium ion homeostasis GO:0006874 119 0.013
sequestering of calcium ion GO:0051208 18 0.013
thioester metabolic process GO:0035383 19 0.013
regulation of body fluid levels GO:0050878 162 0.013
mitotic cell cycle process GO:1903047 159 0.013
regulation of myeloid cell differentiation GO:0045637 96 0.013
renal system development GO:0072001 225 0.013
fatty acid catabolic process GO:0009062 25 0.013
fatty acid transmembrane transport GO:1902001 1 0.013
regulation of protein maturation GO:1903317 96 0.013
response to epidermal growth factor GO:0070849 4 0.013
regulation of heart contraction GO:0008016 77 0.013
compound eye development GO:0048749 1 0.013
carbohydrate transport GO:0008643 62 0.013
intracellular protein transport GO:0006886 204 0.013
positive regulation of cardiac muscle contraction GO:0060452 2 0.013
glycosylation GO:0070085 62 0.013
positive regulation of cellular catabolic process GO:0031331 148 0.013
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.013
glycosyl compound catabolic process GO:1901658 206 0.013
regulation of endopeptidase activity GO:0052548 89 0.013
appendage development GO:0048736 166 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.013
cell growth GO:0016049 130 0.013
epidermis development GO:0008544 187 0.013
regulation of multi organism process GO:0043900 111 0.013
rhythmic process GO:0048511 174 0.013
regulation of secretion by cell GO:1903530 249 0.013
acetate metabolic process GO:0006083 1 0.013
dna metabolic process GO:0006259 303 0.013
nucleoside triphosphate catabolic process GO:0009143 205 0.012
protein glycosylation GO:0006486 55 0.012
mitotic cell cycle GO:0000278 195 0.012
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.012
negative regulation of cellular component organization GO:0051129 194 0.012
peptidyl tyrosine modification GO:0018212 145 0.012
response to starvation GO:0042594 65 0.012
sequestering of metal ion GO:0051238 19 0.012
wound healing GO:0042060 157 0.012
synaptic transmission GO:0007268 329 0.012
calcium ion transmembrane transport GO:0070588 85 0.012
i kappab kinase nf kappab signaling GO:0007249 85 0.012
blood coagulation GO:0007596 76 0.012
potassium ion transmembrane transport GO:0071805 43 0.012
fertilization GO:0009566 127 0.012
glycogen metabolic process GO:0005977 32 0.012
morphogenesis of a branching structure GO:0001763 203 0.012
negative regulation of cell proliferation GO:0008285 296 0.012
macromolecule glycosylation GO:0043413 55 0.012
neuron death GO:0070997 154 0.012
regulation of feeding behavior GO:0060259 3 0.012
adiponectin activated signaling pathway GO:0033211 4 0.012
endocytosis GO:0006897 168 0.012
cellular protein complex assembly GO:0043623 116 0.012
ameboidal type cell migration GO:0001667 128 0.012
germ cell development GO:0007281 185 0.011
response to growth factor GO:0070848 198 0.011
meiotic cell cycle GO:0051321 122 0.011
positive regulation of hydrolase activity GO:0051345 148 0.011
rna processing GO:0006396 105 0.011
tissue homeostasis GO:0001894 115 0.011
gland development GO:0048732 330 0.011
nuclear import GO:0051170 95 0.011
hormone metabolic process GO:0042445 86 0.011
hematopoietic progenitor cell differentiation GO:0002244 143 0.011
nuclear transport GO:0051169 139 0.011
regulation of nucleotide metabolic process GO:0006140 169 0.011
organelle fission GO:0048285 170 0.011
regulation of cellular component size GO:0032535 121 0.011
cellular alcohol biosynthetic process GO:0044108 3 0.011
regulation of fatty acid biosynthetic process GO:0042304 12 0.011
regulation of cell adhesion GO:0030155 154 0.011
nucleoside phosphate biosynthetic process GO:1901293 79 0.011
myosin filament organization GO:0031033 3 0.011
regulation of neuron projection development GO:0010975 169 0.011
regulation of phospholipid catabolic process GO:0060696 2 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
positive regulation of mapk cascade GO:0043410 170 0.011
epithelial cell proliferation GO:0050673 174 0.011
pyridine containing compound metabolic process GO:0072524 14 0.011
glycoprotein biosynthetic process GO:0009101 89 0.011
chromatin organization GO:0006325 206 0.011
nucleoside monophosphate metabolic process GO:0009123 85 0.011
positive regulation of nucleotide metabolic process GO:0045981 114 0.011
regulation of removal of superoxide radicals GO:2000121 4 0.011
regulation of triglyceride metabolic process GO:0090207 17 0.011
limb development GO:0060173 166 0.011
lymphocyte differentiation GO:0030098 242 0.011
regulation of cardiac muscle contraction GO:0055117 21 0.011
regulation of protein processing GO:0070613 96 0.011
epithelial tube morphogenesis GO:0060562 303 0.011
mitotic cytokinesis GO:0000281 4 0.011
response to reactive oxygen species GO:0000302 56 0.011
regulation of mitochondrial fission GO:0090140 3 0.011
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.011
mature dendritic cell differentiation GO:0097029 3 0.011
regulation of metal ion transport GO:0010959 106 0.011
organic hydroxy compound catabolic process GO:1901616 25 0.011
purine containing compound biosynthetic process GO:0072522 70 0.011
angiogenesis GO:0001525 201 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.011
interleukin 8 production GO:0032637 4 0.011
regulation of cell migration GO:0030334 219 0.011
rho protein signal transduction GO:0007266 32 0.011
positive regulation of cell activation GO:0050867 158 0.011
polyamine catabolic process GO:0006598 2 0.010
positive regulation of striated muscle contraction GO:0045989 3 0.010
regulation of blood circulation GO:1903522 93 0.010
organelle localization GO:0051640 179 0.010
oxidoreduction coenzyme metabolic process GO:0006733 16 0.010
cellular alcohol metabolic process GO:0044107 3 0.010
positive regulation of defense response GO:0031349 124 0.010
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.010
regulation of t cell activation GO:0050863 170 0.010
nuclear division GO:0000280 158 0.010
calcium ion homeostasis GO:0055074 127 0.010
primary alcohol metabolic process GO:0034308 11 0.010
xenobiotic catabolic process GO:0042178 1 0.010
glucose homeostasis GO:0042593 128 0.010
fatty acid biosynthetic process GO:0006633 41 0.010
vitamin d biosynthetic process GO:0042368 3 0.010
cardiac muscle cell contraction GO:0086003 7 0.010
myeloid cell homeostasis GO:0002262 114 0.010
interleukin 12 secretion GO:0072610 3 0.010
developmental maturation GO:0021700 193 0.010
regulation of fatty acid beta oxidation GO:0031998 1 0.010
calcitriol biosynthetic process from calciol GO:0036378 3 0.010
regulation of muscle contraction GO:0006937 49 0.010
single organism cell adhesion GO:0098602 156 0.010
regulation of intracellular transport GO:0032386 159 0.010
defense response to bacterium GO:0042742 119 0.010

Pdk4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.048
nervous system disease DOID:863 0 0.048
disease of metabolism DOID:0014667 0 0.031
muscular disease DOID:0080000 0 0.022
musculoskeletal system disease DOID:17 0 0.022
neuromuscular disease DOID:440 0 0.021
neuropathy DOID:870 0 0.021
charcot marie tooth disease DOID:10595 0 0.017
immune system disease DOID:2914 0 0.016
hematopoietic system disease DOID:74 0 0.015
sensory system disease DOID:0050155 0 0.015
eye and adnexa disease DOID:1492 0 0.014
cardiovascular system disease DOID:1287 0 0.013
eye disease DOID:5614 0 0.013
myopathy DOID:423 0 0.013
muscle tissue disease DOID:66 0 0.013
inherited metabolic disorder DOID:655 0 0.012
central nervous system disease DOID:331 0 0.011
acquired metabolic disease DOID:0060158 0 0.011
neurodegenerative disease DOID:1289 0 0.010