Mus musculus

92 known processes

Scn5a

sodium channel, voltage-gated, type V, alpha

(Aliases: mH1,SkM1,Nav1.5,Nav1.5c)

Scn5a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ventricular cardiac muscle cell action potential GO:0086005 4 1.000
atrial ventricular junction remodeling GO:0003294 2 1.000
av node cell to bundle of his cell communication GO:0086067 2 1.000
regulation of membrane depolarization GO:0003254 11 1.000
Mouse
sa node cell to atrial cardiac muscle cell signalling GO:0086018 4 1.000
regulation of renin secretion into blood stream GO:1900133 4 1.000
regulation of ventricular cardiac muscle cell membrane depolarization GO:0060373 2 1.000
cardiac muscle cell action potential involved in contraction GO:0086002 6 0.999
milk ejection GO:0060156 1 0.999
cell communication by electrical coupling involved in cardiac conduction GO:0086064 2 0.999
foramen ovale closure GO:0035922 1 0.998
cell communication by chemical coupling GO:0010643 2 0.997
regulation of blood circulation GO:1903522 93 0.997
sa node cell action potential GO:0086015 4 0.997
cardiac conduction GO:0061337 17 0.997
ion transmembrane transport GO:0034220 361 0.997
cardiac muscle cell contraction GO:0086003 7 0.996
regulation of cardiac muscle contraction GO:0055117 21 0.996
regulation of heart rate GO:0002027 36 0.996
cell cell signaling involved in cardiac conduction GO:0086019 6 0.996
heart contraction GO:0060047 93 0.995
cation transmembrane transport GO:0098655 266 0.994
regulation of membrane potential GO:0042391 192 0.993
regulation of heart contraction GO:0008016 77 0.993
muscle system process GO:0003012 141 0.992
vagus nerve development GO:0021564 3 0.992
regulation of cardiac muscle cell contraction GO:0086004 11 0.992
cardiac muscle cell action potential GO:0086001 11 0.991
sinoatrial node cell differentiation GO:0060921 3 0.991
regulation of membrane depolarization during action potential GO:0098902 1 0.991
regulation of muscle contraction GO:0006937 49 0.987
regulation of ion transmembrane transport GO:0034765 119 0.981
regulation of muscle system process GO:0090257 80 0.980
cardiac ventricle development GO:0003231 83 0.980
actin mediated cell contraction GO:0070252 15 0.980
bundle of his development GO:0003166 4 0.979
mesodermal to mesenchymal transition involved in gastrulation GO:0060809 1 0.979
potassium ion transmembrane transport GO:0071805 43 0.978
sa node cell to atrial cardiac muscle cell communication GO:0086070 5 0.978
multicellular organismal signaling GO:0035637 91 0.978
heart process GO:0003015 94 0.975
membrane repolarization GO:0086009 7 0.974
cellular potassium ion transport GO:0071804 43 0.972
regulation of system process GO:0044057 200 0.970
embryonic heart tube morphogenesis GO:0003143 51 0.964
regulation of ion transport GO:0043269 215 0.962
cardiac muscle contraction GO:0060048 32 0.960
circulatory system process GO:0003013 197 0.959
striated muscle tissue development GO:0014706 293 0.958
muscle contraction GO:0006936 101 0.956
cardiac septum development GO:0003279 59 0.955
regulation of heart rate by cardiac conduction GO:0086091 6 0.954
regulation of ion homeostasis GO:2000021 64 0.952
Mouse
regulation of atrial cardiac muscle cell membrane depolarization GO:0060371 5 0.951
Mouse
transmembrane transport GO:0055085 412 0.951
striated muscle contraction GO:0006941 45 0.949
regulation of actin filament based process GO:0032970 99 0.947
actin filament based movement GO:0030048 23 0.944
inorganic cation transmembrane transport GO:0098662 207 0.939
regulation of membrane repolarization GO:0060306 7 0.939
regulation of skeletal muscle fiber differentiation GO:1902809 3 0.936
potassium ion transport GO:0006813 52 0.933
neuron migration GO:0001764 122 0.933
blood circulation GO:0008015 195 0.933
positive regulation of heart rate GO:0010460 10 0.930
Rat
positive regulation of cardioblast differentiation GO:0051891 3 0.926
his purkinje system cell differentiation GO:0060932 2 0.920
regulation of membrane depolarization during cardiac muscle cell action potential GO:1900825 1 0.918
sensory perception of mechanical stimulus GO:0050954 107 0.917
Mouse
regulation of cardiac chamber formation GO:1901210 1 0.917
cardiac septum morphogenesis GO:0060411 46 0.915
septum primum development GO:0003284 4 0.912
positive regulation of skeletal muscle cell differentiation GO:2001016 4 0.911
action potential GO:0001508 78 0.911
sinoatrial node cell development GO:0060931 3 0.906
regulation of ventricular cardiac muscle cell membrane repolarization GO:0060307 5 0.905
ventricular septum development GO:0003281 42 0.902
cardiac left ventricle morphogenesis GO:0003214 9 0.901
cell communication involved in cardiac conduction GO:0086065 9 0.896
positive regulation of skeletal muscle fiber differentiation GO:1902811 2 0.894
inorganic ion transmembrane transport GO:0098660 234 0.894
negative regulation of cardiac chamber morphogenesis GO:1901220 2 0.892
regulation of striated muscle contraction GO:0006942 25 0.888
positive regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901228 4 0.885
muscle tissue development GO:0060537 308 0.882
tricuspid valve development GO:0003175 3 0.881
embryonic heart tube development GO:0035050 65 0.879
regulation of actin filament based movement GO:1903115 12 0.877
regulation of heart looping GO:1901207 1 0.874
sodium ion transmembrane transport GO:0035725 49 0.870
positive regulation of tongue muscle cell differentiation GO:2001037 2 0.870
regulation of tongue muscle cell differentiation GO:2001035 2 0.865
neuronal action potential GO:0019228 54 0.864
Mouse
regulation of cardioblast differentiation GO:0051890 3 0.861
cardiac muscle tissue morphogenesis GO:0055008 44 0.861
visceral motor neuron differentiation GO:0021524 3 0.861
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003257 3 0.860
heart morphogenesis GO:0003007 178 0.848
ventricular septum morphogenesis GO:0060412 27 0.838
sensory perception GO:0007600 245 0.832
Mouse
negative regulation of cardiac chamber formation GO:1901211 1 0.829
membrane depolarization during cardiac muscle cell action potential GO:0086012 5 0.828
cardiac muscle tissue development GO:0048738 130 0.828
ear morphogenesis GO:0042471 118 0.818
retinal cone cell development GO:0046549 8 0.813
cation transport GO:0006812 399 0.808
artery development GO:0060840 53 0.790
response to purine containing compound GO:0014074 28 0.782
pulmonary valve formation GO:0003193 1 0.780
regulation of satellite cell activation involved in skeletal muscle regeneration GO:0014717 3 0.778
transmission of nerve impulse GO:0019226 76 0.778
Mouse
reflex GO:0060004 22 0.770
regulation of transmembrane transport GO:0034762 128 0.765
tongue muscle cell differentiation GO:0035981 2 0.764
fertilization GO:0009566 127 0.764
vagus nerve morphogenesis GO:0021644 2 0.760
canonical wnt signaling pathway involved in neural plate anterior posterior pattern formation GO:0060823 1 0.759
cardiac atrium development GO:0003230 24 0.722
cardiac chamber development GO:0003205 108 0.722
biomineral tissue development GO:0031214 64 0.720
axon ensheathment GO:0008366 76 0.716
positive regulation of striated muscle tissue development GO:0045844 31 0.710
skeletal muscle fiber development GO:0048741 58 0.697
ventricular cardiac muscle tissue development GO:0003229 38 0.697
skeletal system development GO:0001501 356 0.691
membrane depolarization during action potential GO:0086010 5 0.688
embryonic appendage morphogenesis GO:0035113 126 0.684
regulation of canonical wnt signaling pathway involved in neural plate anterior posterior pattern formation GO:0060827 1 0.683
muscle fiber development GO:0048747 76 0.680
his purkinje system development GO:0003164 4 0.678
septum transversum development GO:0003343 2 0.672
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressure GO:0001999 6 0.671
atrioventricular bundle cell differentiation GO:0003167 1 0.668
detection of stimulus involved in sensory perception GO:0050906 44 0.652
cardiac chamber morphogenesis GO:0003206 93 0.645
stem cell differentiation GO:0048863 268 0.642
positive regulation of muscle tissue development GO:1901863 32 0.639
sodium ion transport GO:0006814 73 0.638
sensory perception of sound GO:0007605 97 0.635
Mouse
cell type specific apoptotic process GO:0097285 268 0.635
Mouse
regulation of cardiac chamber morphogenesis GO:1901219 2 0.632
embryonic organ morphogenesis GO:0048562 276 0.629
cell differentiation involved in embryonic placenta development GO:0060706 26 0.625
response to organic cyclic compound GO:0014070 198 0.621
atrial septum morphogenesis GO:0060413 11 0.617
clara cell differentiation GO:0060486 4 0.614
sinoatrial node development GO:0003163 4 0.602
g protein coupled receptor signaling pathway GO:0007186 243 0.595
vasodilation GO:0042311 28 0.594
mammary placode formation GO:0060596 4 0.593
spongiotrophoblast layer development GO:0060712 15 0.582
negative regulation of canonical wnt signaling pathway involved in neural plate anterior posterior pattern formation GO:0060829 1 0.574
negative regulation of smad protein complex assembly GO:0010991 1 0.573
negative regulation of cardiac muscle tissue development GO:0055026 8 0.565
embryonic digit morphogenesis GO:0042733 56 0.557
canonical wnt signaling pathway GO:0060070 130 0.555
determination of left right symmetry GO:0007368 80 0.550
tissue remodeling GO:0048771 102 0.549
regulation of systemic arterial blood pressure by hormone GO:0001990 25 0.547
muscle cell differentiation GO:0042692 261 0.542
purine nucleoside catabolic process GO:0006152 205 0.539
sensory organ morphogenesis GO:0090596 242 0.523
sensory perception of smell GO:0007608 26 0.523
appendage morphogenesis GO:0035107 149 0.517
muscle cell fate specification GO:0042694 1 0.517
cardiac conduction system development GO:0003161 12 0.513
detection of stimulus GO:0051606 84 0.513
bmp signaling pathway GO:0030509 93 0.512
single fertilization GO:0007338 82 0.506
embryonic limb morphogenesis GO:0030326 126 0.503
cell cell junction organization GO:0045216 72 0.491
regulation of secretion by cell GO:1903530 249 0.490
cellular response to organic cyclic compound GO:0071407 87 0.489
enamel mineralization GO:0070166 7 0.484
cellular response to camp GO:0071320 11 0.483
regulation of cell activation GO:0050865 289 0.477
cd8 positive alpha beta t cell differentiation involved in immune response GO:0002302 2 0.475
cardiac muscle cell development GO:0055013 39 0.474
ventricular cardiac muscle tissue morphogenesis GO:0055010 32 0.472
ventricular cardiac myofibril assembly GO:0055005 3 0.471
eye photoreceptor cell development GO:0042462 31 0.465
retina development in camera type eye GO:0060041 119 0.463
regulation of cardiac muscle cell action potential GO:0098901 1 0.462
positive regulation of protein modification process GO:0031401 299 0.457
hindbrain development GO:0030902 128 0.454
Rat
follicle stimulating hormone secretion GO:0046884 1 0.454
regulation of cardiac muscle tissue growth GO:0055021 26 0.453
regulation of heart growth GO:0060420 31 0.453
nucleotide catabolic process GO:0009166 217 0.447
pulmonary valve development GO:0003177 5 0.441
regulation of homeostatic process GO:0032844 182 0.438
Mouse
limb development GO:0060173 166 0.437
regulation of neuron projection development GO:0010975 169 0.435
vascular process in circulatory system GO:0003018 62 0.428
bone mineralization GO:0030282 54 0.427
positive regulation of muscle contraction GO:0045933 10 0.420
muscle tissue morphogenesis GO:0060415 53 0.415
camera type eye development GO:0043010 266 0.414
placenta development GO:0001890 140 0.414
optic nerve development GO:0021554 8 0.414
detection of light stimulus GO:0009583 25 0.412
proepicardium development GO:0003342 2 0.411
sensory perception of chemical stimulus GO:0007606 51 0.406
atrial cardiac muscle cell development GO:0055014 2 0.401
ensheathment of neurons GO:0007272 76 0.396
smad protein complex assembly GO:0007183 1 0.394
positive regulation of transcription via serum response element binding GO:0010735 1 0.393
mesenchymal cell proliferation involved in ureter development GO:0072198 4 0.392
cardiac left ventricle formation GO:0003218 1 0.388
commitment of neuronal cell to specific neuron type in forebrain GO:0021902 7 0.388
response to organophosphorus GO:0046683 22 0.383
ear development GO:0043583 200 0.382
mapk cascade GO:0000165 281 0.382
cardiac cell development GO:0055006 41 0.379
regulation of cardiac muscle cell proliferation GO:0060043 23 0.372
detection of light stimulus involved in sensory perception GO:0050962 8 0.369
negative regulation of organ growth GO:0046621 17 0.367
purine ribonucleotide metabolic process GO:0009150 290 0.363
striated muscle cell development GO:0055002 125 0.360
detection of visible light GO:0009584 14 0.358
regulation of anatomical structure size GO:0090066 178 0.356
positive regulation of cellular catabolic process GO:0031331 148 0.354
labyrinthine layer morphogenesis GO:0060713 21 0.354
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.348
negative regulation of cell migration GO:0030336 59 0.346
response to light stimulus GO:0009416 135 0.345
atrioventricular node cell differentiation GO:0060922 2 0.342
synapse organization GO:0050808 125 0.342
retinal cone cell differentiation GO:0042670 8 0.339
regulation of systemic arterial blood pressure GO:0003073 61 0.337
atrial septum development GO:0003283 12 0.332
regulation of wnt signaling pathway GO:0030111 123 0.332
positive regulation of protein phosphorylation GO:0001934 242 0.331
embryonic heart tube elongation GO:0036306 1 0.331
organ growth GO:0035265 117 0.331
myelination GO:0042552 74 0.329
regulation of canonical wnt signaling pathway GO:0060828 82 0.321
regulation of purine nucleotide catabolic process GO:0033121 122 0.318
positive regulation of hydrolase activity GO:0051345 148 0.317
ribonucleoside triphosphate metabolic process GO:0009199 220 0.316
negative regulation of cardiac muscle tissue growth GO:0055022 7 0.316
detection of light stimulus involved in visual perception GO:0050908 8 0.308
positive regulation of osteoblast differentiation GO:0045669 34 0.307
sensory perception of light stimulus GO:0050953 54 0.306
cardiac muscle cell differentiation GO:0055007 69 0.305
ribonucleotide catabolic process GO:0009261 208 0.302
regulation of cellular ketone metabolic process GO:0010565 66 0.299
purine containing compound catabolic process GO:0072523 213 0.297
purine nucleoside metabolic process GO:0042278 241 0.296
nucleoside phosphate metabolic process GO:0006753 338 0.291
chemosensory behavior GO:0007635 11 0.290
regulation of protein localization GO:0032880 231 0.288
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.286
regionalization GO:0003002 337 0.286
regulation of protein transport GO:0051223 163 0.285
skeletal muscle satellite cell activation GO:0014719 5 0.283
inner ear morphogenesis GO:0042472 101 0.282
regulation of osteoblast differentiation GO:0045667 67 0.280
regulation of nucleoside metabolic process GO:0009118 130 0.276
nucleoside triphosphate catabolic process GO:0009143 205 0.276
regulation of cation channel activity GO:2001257 22 0.275
amine metabolic process GO:0009308 45 0.275
labyrinthine layer development GO:0060711 49 0.272
cardiac ventricle morphogenesis GO:0003208 50 0.271
ossification GO:0001503 216 0.269
positive regulation of ion transmembrane transporter activity GO:0032414 15 0.266
regulation of vasodilation GO:0042312 5 0.260
cardiocyte differentiation GO:0035051 87 0.259
branching morphogenesis of an epithelial tube GO:0048754 159 0.250
leukocyte differentiation GO:0002521 342 0.250
detection of external stimulus GO:0009581 61 0.248
regulation of establishment of protein localization GO:0070201 181 0.244
regulation of cell projection organization GO:0031344 206 0.244
response to camp GO:0051591 14 0.242
negative regulation of cell motility GO:2000146 61 0.239
olfactory bulb development GO:0021772 30 0.238
cellular amine metabolic process GO:0044106 44 0.238
visual perception GO:0007601 52 0.237
protein secretion GO:0009306 111 0.234
atrial cardiac muscle cell differentiation GO:0055011 2 0.234
positive regulation of heart contraction GO:0045823 14 0.233
Rat
atrioventricular node cell development GO:0060928 2 0.232
organonitrogen compound catabolic process GO:1901565 264 0.229
renin secretion into blood stream GO:0002001 5 0.227
blood vessel morphogenesis GO:0048514 285 0.224
cellular response to organonitrogen compound GO:0071417 145 0.224
central nervous system neuron differentiation GO:0021953 162 0.223
cardiac muscle cell proliferation GO:0060038 31 0.222
ameboidal type cell migration GO:0001667 128 0.222
negative regulation of cardiac muscle cell proliferation GO:0060044 5 0.220
positive regulation of b cell activation GO:0050871 49 0.220
mesonephric duct formation GO:0072181 2 0.220
ribonucleoside catabolic process GO:0042454 206 0.217
regulation of mesenchymal cell proliferation involved in ureter development GO:0072199 3 0.216
endocrine process GO:0050886 39 0.211
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.210
regulation of smad protein complex assembly GO:0010990 1 0.210
glycosyl compound catabolic process GO:1901658 206 0.208
cardiac pacemaker cell fate commitment GO:0060927 1 0.207
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.207
positive regulation of atpase activity GO:0032781 3 0.205
cardiac pacemaker cell differentiation GO:0060920 5 0.204
embryonic placenta development GO:0001892 98 0.203
pharynx development GO:0060465 1 0.198
cellular nitrogen compound catabolic process GO:0044270 280 0.197
regulation of mapk cascade GO:0043408 248 0.197
adrenergic receptor signaling pathway GO:0071875 13 0.197
positive regulation of nucleotide catabolic process GO:0030813 88 0.193
regulation of cell migration GO:0030334 219 0.192
regulation of purine nucleotide metabolic process GO:1900542 169 0.192
membrane depolarization GO:0051899 64 0.191
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.191
transition metal ion transport GO:0000041 38 0.189
eye photoreceptor cell differentiation GO:0001754 41 0.187
interferon gamma production GO:0032609 67 0.186
alpha beta t cell activation GO:0046631 91 0.186
positive regulation of epithelial cell proliferation GO:0050679 68 0.183
Rat
positive regulation of organ growth GO:0046622 29 0.183
retina morphogenesis in camera type eye GO:0060042 45 0.181
regulation of nucleotide metabolic process GO:0006140 169 0.180
multi multicellular organism process GO:0044706 109 0.180
multicellular organismal response to stress GO:0033555 62 0.180
Mouse
negative regulation of cell proliferation GO:0008285 296 0.178
spinal cord oligodendrocyte cell fate specification GO:0021530 3 0.176
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.176
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.176
heterocycle catabolic process GO:0046700 280 0.176
peptidyl tyrosine modification GO:0018212 145 0.175
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.175
regulation of systemic arterial blood pressure by renin angiotensin GO:0003081 20 0.174
cellular response to growth factor stimulus GO:0071363 197 0.172
determination of heart left right asymmetry GO:0061371 48 0.172
positive regulation of cellular amine metabolic process GO:0033240 5 0.171
regulation of nucleotide catabolic process GO:0030811 122 0.170
positive regulation of blood circulation GO:1903524 22 0.169
Rat
purine nucleotide metabolic process GO:0006163 302 0.166
regulation of cardiac muscle tissue development GO:0055024 31 0.166
immune effector process GO:0002252 321 0.165
nucleobase containing small molecule metabolic process GO:0055086 352 0.164
uterus morphogenesis GO:0061038 2 0.164
muscle cell development GO:0055001 133 0.164
cardiac pacemaker cell development GO:0060926 5 0.164
regulation of adaptive immune response GO:0002819 90 0.163
regulation of organ growth GO:0046620 61 0.163
regulation of blood vessel size GO:0050880 56 0.163
cerebral cortex neuron differentiation GO:0021895 19 0.163
positive regulation of nucleotide metabolic process GO:0045981 114 0.162
aromatic compound catabolic process GO:0019439 286 0.162
specification of organ position GO:0010159 3 0.160
cell junction organization GO:0034330 77 0.160
mesenchyme development GO:0060485 152 0.159
atrioventricular node cell fate commitment GO:0060929 1 0.158
central nervous system morphogenesis GO:0021551 2 0.157
spongiotrophoblast differentiation GO:0060708 4 0.157
male sex differentiation GO:0046661 109 0.156
forebrain development GO:0030900 302 0.156
Rat
leukocyte migration GO:0050900 124 0.156
regulation of cellular component biogenesis GO:0044087 181 0.155
regulation of biomineral tissue development GO:0070167 33 0.155
regulation of neuron differentiation GO:0045664 281 0.154
gonad development GO:0008406 141 0.153
positive regulation of lymphocyte activation GO:0051251 140 0.152
positive regulation of voltage gated calcium channel activity GO:1901387 2 0.151
t cell activation involved in immune response GO:0002286 43 0.150
urogenital system development GO:0001655 261 0.150
renal outer medulla development GO:0072054 2 0.150
spinal cord oligodendrocyte cell differentiation GO:0021529 3 0.149
regulation of ossification GO:0030278 112 0.149
skeletal muscle cell differentiation GO:0035914 66 0.148
skeletal muscle organ development GO:0060538 163 0.148
regulation of lymphocyte activation GO:0051249 240 0.148
cell maturation GO:0048469 127 0.147
outflow tract morphogenesis GO:0003151 53 0.147
nucleotide metabolic process GO:0009117 332 0.146
regulation of secretion GO:0051046 274 0.146
lens development in camera type eye GO:0002088 62 0.145
tertiary branching involved in mammary gland duct morphogenesis GO:0060748 3 0.144
leukocyte mediated immunity GO:0002443 174 0.144
regulation of hormone levels GO:0010817 211 0.144
negative regulation of growth GO:0045926 99 0.143
wound healing GO:0042060 157 0.142
t cell activation GO:0042110 289 0.142
regulation of leukocyte mediated immunity GO:0002703 104 0.141
limb morphogenesis GO:0035108 149 0.141
positive regulation of nucleoside metabolic process GO:0045979 91 0.140
purine ribonucleoside metabolic process GO:0046128 241 0.140
ventral spinal cord interneuron fate determination GO:0060580 1 0.138
stem cell development GO:0048864 219 0.138
regulation of skeletal muscle tissue regeneration GO:0043416 5 0.137
endocardial cushion development GO:0003197 26 0.136
endocardial cushion morphogenesis GO:0003203 18 0.135
regulation of cellular amino acid metabolic process GO:0006521 5 0.134
cardiac myofibril assembly GO:0055003 12 0.134
positive regulation of ryanodine sensitive calcium release channel activity GO:0060316 1 0.134
purine ribonucleotide catabolic process GO:0009154 208 0.134
ribonucleoside triphosphate catabolic process GO:0009203 199 0.133
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.132
pharyngeal system development GO:0060037 17 0.132
camera type eye photoreceptor cell differentiation GO:0060219 15 0.132
response to radiation GO:0009314 165 0.131
regulation of bone mineralization GO:0030500 31 0.130
synapse assembly GO:0007416 56 0.129
cardiac muscle cell myoblast differentiation GO:0060379 8 0.129
negative regulation of neuron differentiation GO:0045665 101 0.129
regulation of tissue remodeling GO:0034103 38 0.126
regulation of ryanodine sensitive calcium release channel activity GO:0060314 10 0.125
satellite cell activation involved in skeletal muscle regeneration GO:0014901 3 0.125
response to fibroblast growth factor GO:0071774 47 0.125
macromolecule catabolic process GO:0009057 281 0.124
pituitary gland development GO:0021983 38 0.124
photoreceptor cell development GO:0042461 40 0.123
nucleoside triphosphate metabolic process GO:0009141 230 0.123
mesodermal cell migration GO:0008078 4 0.122
lymphocyte differentiation GO:0030098 242 0.122
rho protein signal transduction GO:0007266 32 0.121
response to organonitrogen compound GO:0010243 246 0.120
epithelial cell proliferation GO:0050673 174 0.118
Rat
purine nucleoside triphosphate metabolic process GO:0009144 226 0.118
synaptic transmission GO:0007268 329 0.118
epithelial tube morphogenesis GO:0060562 303 0.117
cellular chemical homeostasis GO:0055082 215 0.117
negative regulation of cell development GO:0010721 169 0.115
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.115
regulation of metal ion transport GO:0010959 106 0.115
regulation of protein complex assembly GO:0043254 83 0.115
positive regulation of ossification GO:0045778 47 0.114
lymphocyte mediated immunity GO:0002449 139 0.114
autonomic nervous system development GO:0048483 43 0.113
forebrain generation of neurons GO:0021872 63 0.113
embryonic placenta morphogenesis GO:0060669 25 0.113
heart growth GO:0060419 45 0.113
alpha beta t cell differentiation GO:0046632 69 0.113
positive regulation of leukocyte mediated immunity GO:0002705 70 0.113
t cell proliferation GO:0042098 120 0.112
calcium ion transmembrane transport GO:0070588 85 0.112
regulation of lymphocyte mediated immunity GO:0002706 84 0.110
appendage development GO:0048736 166 0.110
positive regulation of cation channel activity GO:2001259 8 0.110
olfactory lobe development GO:0021988 32 0.110
purine nucleotide catabolic process GO:0006195 211 0.109
skeletal muscle tissue regeneration GO:0043403 20 0.109
endocrine system development GO:0035270 98 0.109
neural retina development GO:0003407 41 0.109
immunoglobulin production GO:0002377 73 0.108
positive regulation of immune effector process GO:0002699 107 0.107
cardiac atrium morphogenesis GO:0003209 23 0.106
respiratory system development GO:0060541 190 0.106
myeloid leukocyte differentiation GO:0002573 119 0.105
purine nucleoside monophosphate catabolic process GO:0009128 58 0.104
amelogenesis GO:0097186 12 0.103
positive regulation of mapk cascade GO:0043410 170 0.103
endocytosis GO:0006897 168 0.102
pancreatic a cell fate commitment GO:0003326 2 0.102
response to drug GO:0042493 75 0.102
cell adhesion GO:0007155 329 0.101
positive regulation of map kinase activity GO:0043406 84 0.101
organ maturation GO:0048799 17 0.101
nucleoside metabolic process GO:0009116 246 0.101
positive regulation of stem cell differentiation GO:2000738 23 0.100
regulation of b cell activation GO:0050864 81 0.099
cellular homeostasis GO:0019725 240 0.099
regulation of stem cell proliferation GO:0072091 78 0.099
negative regulation of neuron projection development GO:0010977 50 0.099
forebrain neuron differentiation GO:0021879 52 0.098
organic cyclic compound catabolic process GO:1901361 295 0.098
menarche GO:0042696 1 0.098
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0010880 10 0.098
renal system process GO:0003014 48 0.098
bone morphogenesis GO:0060349 78 0.098
cochlea morphogenesis GO:0090103 22 0.097
lateral inhibition GO:0046331 1 0.097
purine nucleoside triphosphate catabolic process GO:0009146 203 0.096
odontogenesis GO:0042476 78 0.096
Rat
cell communication by electrical coupling GO:0010644 4 0.096
axonogenesis GO:0007409 274 0.096
myotube cell development GO:0014904 60 0.095
regulation of systemic arterial blood pressure by circulatory renin angiotensin GO:0001991 13 0.095
cell differentiation in spinal cord GO:0021515 53 0.094
cellular metal ion homeostasis GO:0006875 151 0.093
cellular ketone metabolic process GO:0042180 84 0.093
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.093
heart valve morphogenesis GO:0003179 21 0.092
cytosolic calcium ion homeostasis GO:0051480 70 0.092
isotype switching GO:0045190 36 0.091
cellular amino acid metabolic process GO:0006520 103 0.090
b cell activation involved in immune response GO:0002312 50 0.090
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.089

Scn5a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.997
cardiovascular system disease DOID:1287 0 0.997
musculoskeletal system disease DOID:17 0 0.456
heart conduction disease DOID:10273 0 0.422
heart disease DOID:114 0 0.295
myopathy DOID:423 0 0.197
muscular disease DOID:0080000 0 0.197
cardiomyopathy DOID:0050700 0 0.197
intrinsic cardiomyopathy DOID:0060036 0 0.197
arrhythmogenic right ventricular cardiomyopathy DOID:0050431 0 0.197
muscle tissue disease DOID:66 0 0.197