Mus musculus

13 known processes

Gja4

gap junction protein, alpha 4

(Aliases: AW558810,Gja-4,Cx37,Cnx37,AU020209)

Gja4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
renal system development GO:0072001 225 0.562
urogenital system development GO:0001655 261 0.516
blood vessel morphogenesis GO:0048514 285 0.480
Mouse
kidney development GO:0001822 213 0.470
immune effector process GO:0002252 321 0.460
nephron development GO:0072006 109 0.424
heart morphogenesis GO:0003007 178 0.389
Mouse
skeletal system morphogenesis GO:0048705 203 0.380
cell adhesion GO:0007155 329 0.377
astrocyte fate commitment GO:0060018 4 0.352
lung development GO:0030324 164 0.323
stem cell development GO:0048864 219 0.304
cell type specific apoptotic process GO:0097285 268 0.298
regulation of cell motility GO:2000145 236 0.291
positive regulation of protein phosphorylation GO:0001934 242 0.289
nephron epithelium morphogenesis GO:0072088 68 0.289
ameboidal type cell migration GO:0001667 128 0.278
renal tubule development GO:0061326 87 0.270
mitral valve development GO:0003174 4 0.264
mesonephric tubule development GO:0072164 94 0.260
stem cell fate specification GO:0048866 3 0.259
regulation of vasculature development GO:1901342 88 0.256
mitral valve morphogenesis GO:0003183 4 0.251
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.240
ureteric bud development GO:0001657 94 0.240
embryonic organ morphogenesis GO:0048562 276 0.229
Mouse
artery development GO:0060840 53 0.227
Mouse
bone development GO:0060348 120 0.224
stem cell maintenance GO:0019827 130 0.221
epithelial cell proliferation GO:0050673 174 0.218
single organism cell adhesion GO:0098602 156 0.215
positive regulation of nervous system development GO:0051962 221 0.211
sensory organ morphogenesis GO:0090596 242 0.209
Mouse
ureteric bud morphogenesis GO:0060675 62 0.206
mesonephros development GO:0001823 97 0.204
positive regulation of cell development GO:0010720 237 0.202
neural crest cell migration GO:0001755 32 0.201
cellular ketone metabolic process GO:0042180 84 0.195
cardiac muscle tissue development GO:0048738 130 0.192
Mouse
nephron tubule development GO:0072080 84 0.191
single organismal cell cell adhesion GO:0016337 131 0.191
axonogenesis GO:0007409 274 0.189
epithelial tube morphogenesis GO:0060562 303 0.188
Mouse
kidney epithelium development GO:0072073 121 0.187
regulation of cell adhesion GO:0030155 154 0.186
t cell differentiation GO:0030217 174 0.184
striated muscle cell development GO:0055002 125 0.175
cardiac muscle cell development GO:0055013 39 0.175
skeletal muscle organ development GO:0060538 163 0.170
skin development GO:0043588 220 0.169
muscle cell differentiation GO:0042692 261 0.169
positive regulation of protein modification process GO:0031401 299 0.167
cytokine production GO:0001816 319 0.167
negative regulation of immune system process GO:0002683 209 0.164
cardiac chamber morphogenesis GO:0003206 93 0.161
Mouse
regionalization GO:0003002 337 0.159
morphogenesis of embryonic epithelium GO:0016331 159 0.159
regulation of epithelial cell proliferation GO:0050678 141 0.157
satellite cell activation involved in skeletal muscle regeneration GO:0014901 3 0.154
Mouse
fat cell differentiation GO:0045444 160 0.152
cellular response to growth factor stimulus GO:0071363 197 0.150
circulatory system process GO:0003013 197 0.149
Mouse
neuron projection guidance GO:0097485 141 0.149
regulation of muscle tissue development GO:1901861 97 0.146
Mouse
regulation of angiogenesis GO:0045765 81 0.145
developmental maturation GO:0021700 193 0.141
Mouse
nephron epithelium development GO:0072009 92 0.140
pallium development GO:0021543 120 0.137
cellular amino acid metabolic process GO:0006520 103 0.135
stem cell differentiation GO:0048863 268 0.133
regulation of cell activation GO:0050865 289 0.132
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.132
septum primum development GO:0003284 4 0.132
Mouse
phosphatidylinositol 3 kinase signaling GO:0014065 36 0.130
cardiac ventricle morphogenesis GO:0003208 50 0.129
striated muscle tissue development GO:0014706 293 0.123
Mouse
regulation of cellular component biogenesis GO:0044087 181 0.123
positive regulation of neuron differentiation GO:0045666 141 0.122
ear development GO:0043583 200 0.122
Mouse
mesonephric tubule morphogenesis GO:0072171 63 0.121
cardiocyte differentiation GO:0035051 87 0.120
extracellular structure organization GO:0043062 148 0.119
extracellular matrix organization GO:0030198 147 0.116
leukocyte differentiation GO:0002521 342 0.116
neural crest cell development GO:0014032 48 0.114
positive regulation of cellular component biogenesis GO:0044089 94 0.113
sensory perception of sound GO:0007605 97 0.112
Mouse
cerebral cortex development GO:0021987 86 0.112
cellular homeostasis GO:0019725 240 0.112
regulation of neuron differentiation GO:0045664 281 0.109
peptidyl amino acid modification GO:0018193 336 0.106
regulation of protein localization GO:0032880 231 0.106
Mouse
ossification GO:0001503 216 0.106
Mouse
angiogenesis GO:0001525 201 0.106
regulation of organ morphogenesis GO:2000027 144 0.105
negative regulation of protein metabolic process GO:0051248 282 0.105
lymphocyte differentiation GO:0030098 242 0.103
renal vesicle induction GO:0072034 3 0.102
digestive tract morphogenesis GO:0048546 147 0.101
mesenchymal cell development GO:0014031 93 0.101
response to growth factor GO:0070848 198 0.099
mapk cascade GO:0000165 281 0.099
intestinal epithelial structure maintenance GO:0060729 4 0.097
muscle cell development GO:0055001 133 0.097
regulation of system process GO:0044057 200 0.096
Mouse
mesenchymal cell differentiation GO:0048762 107 0.095
regulation of cellular ketone metabolic process GO:0010565 66 0.095
apoptotic signaling pathway GO:0097190 306 0.095
erythrocyte differentiation GO:0030218 88 0.095
chondrocyte development GO:0002063 24 0.094
digestive tract development GO:0048565 190 0.094
negative regulation of cell migration GO:0030336 59 0.094
regulation of hormone levels GO:0010817 211 0.093
negative regulation of intracellular signal transduction GO:1902532 167 0.093
chondrocyte differentiation GO:0002062 72 0.091
cellular chemical homeostasis GO:0055082 215 0.090
neural crest cell differentiation GO:0014033 54 0.089
stem cell proliferation GO:0072089 117 0.087
endodermal cell fate determination GO:0007493 2 0.087
cell differentiation in spinal cord GO:0021515 53 0.086
cation homeostasis GO:0055080 212 0.086
glycoprotein metabolic process GO:0009100 116 0.086
respiratory system development GO:0060541 190 0.086
hair cycle GO:0042633 90 0.086
regulation of secretion GO:0051046 274 0.085
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.085
regulation of striated muscle cell differentiation GO:0051153 81 0.085
regulation of secretion by cell GO:1903530 249 0.085
Mouse
mesonephric epithelium development GO:0072163 94 0.084
nephron tubule morphogenesis GO:0072078 68 0.084
b cell activation GO:0042113 161 0.084
camera type eye development GO:0043010 266 0.083
Mouse
muscle contraction GO:0006936 101 0.083
positive regulation of secretion GO:0051047 130 0.083
lung alveolus development GO:0048286 45 0.083
transmembrane transport GO:0055085 412 0.082
Mouse
somite development GO:0061053 81 0.082
regulation of vasculogenesis GO:2001212 9 0.081
regulation of cell migration GO:0030334 219 0.081
skeletal muscle fiber development GO:0048741 58 0.081
cardiac cell development GO:0055006 41 0.080
regulation of hippo signaling GO:0035330 1 0.080
male germ line sex determination GO:0019100 2 0.080
positive regulation of epithelial cell proliferation GO:0050679 68 0.080
regulation of anatomical structure size GO:0090066 178 0.080
Mouse
respiratory tube development GO:0030323 167 0.078
positive regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathway GO:0035793 1 0.078
ascending aorta morphogenesis GO:0035910 3 0.078
atrial septum primum morphogenesis GO:0003289 3 0.078
small gtpase mediated signal transduction GO:0007264 97 0.078
positive regulation of cell migration GO:0030335 109 0.077
limb development GO:0060173 166 0.077
Mouse
endodermal cell fate specification GO:0001714 4 0.077
regulation of branching involved in ureteric bud morphogenesis GO:0090189 22 0.076
regulation of cell projection organization GO:0031344 206 0.076
g protein coupled receptor signaling pathway GO:0007186 243 0.075
cardiac muscle fiber development GO:0048739 4 0.075
epidermis development GO:0008544 187 0.075
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.075
regulation of transferase activity GO:0051338 263 0.074
regulation of neuron projection development GO:0010975 169 0.074
carbohydrate derivative biosynthetic process GO:1901137 183 0.074
muscle tissue development GO:0060537 308 0.074
Mouse
branching involved in ureteric bud morphogenesis GO:0001658 56 0.073
appendage development GO:0048736 166 0.073
Mouse
mesenchyme development GO:0060485 152 0.072
cellular response to lipid GO:0071396 145 0.072
regulation of transmembrane transport GO:0034762 128 0.072
Mouse
cell fate determination GO:0001709 32 0.071
mitochondrion organization GO:0007005 134 0.071
cardiac endothelial cell differentiation GO:0003348 4 0.071
positive regulation of secretion by cell GO:1903532 114 0.070
ascending aorta development GO:0035905 3 0.070
endoderm formation GO:0001706 20 0.069
protein import into nucleus GO:0006606 95 0.069
negative regulation of cell motility GO:2000146 61 0.068
ion transmembrane transport GO:0034220 361 0.068
Mouse
cation transport GO:0006812 399 0.068
positive regulation of growth GO:0045927 104 0.068
sensory perception of mechanical stimulus GO:0050954 107 0.068
Mouse
positive regulation of protein secretion GO:0050714 52 0.067
spinal cord development GO:0021510 81 0.066
gastrulation GO:0007369 116 0.066
negative regulation of apoptotic signaling pathway GO:2001234 104 0.066
embryonic placenta development GO:0001892 98 0.066
Mouse
positive regulation of angiogenesis GO:0045766 46 0.066
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.066
regulation of wnt signaling pathway GO:0030111 123 0.066
development of primary sexual characteristics GO:0045137 143 0.065
blood circulation GO:0008015 195 0.065
Mouse
cellular response to abiotic stimulus GO:0071214 56 0.065
metanephros development GO:0001656 79 0.065
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.065
regulation of rho gtpase activity GO:0032319 58 0.065
leukocyte migration GO:0050900 124 0.065
mesoderm development GO:0007498 100 0.065
aortic valve morphogenesis GO:0003180 4 0.064
tissue migration GO:0090130 68 0.064
wound healing GO:0042060 157 0.064
Mouse
renal tubule morphogenesis GO:0061333 72 0.064
multicellular organismal homeostasis GO:0048871 164 0.063
metal ion homeostasis GO:0055065 189 0.063
neuron migration GO:0001764 122 0.063
Mouse
digestive system development GO:0055123 200 0.063
cardiac muscle tissue morphogenesis GO:0055008 44 0.062
palate development GO:0060021 76 0.062
epithelial tube formation GO:0072175 130 0.062
morphogenesis of a branching structure GO:0001763 203 0.061
positive regulation of cell motility GO:2000147 116 0.061
cardiac ventricle development GO:0003231 83 0.061
Mouse
regulation of mitotic cell cycle GO:0007346 126 0.061
regulation of membrane potential GO:0042391 192 0.060
Mouse
outflow tract morphogenesis GO:0003151 53 0.060
retinal blood vessel morphogenesis GO:0061304 3 0.060
neural tube formation GO:0001841 108 0.060
mesodermal cell migration GO:0008078 4 0.060
neural tube development GO:0021915 160 0.059
regulation of lymphocyte activation GO:0051249 240 0.059
positive regulation of mesonephros development GO:0061213 20 0.059
mesoderm morphogenesis GO:0048332 64 0.059
embryonic skeletal system morphogenesis GO:0048704 91 0.059
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.058
regulation of protein serine threonine kinase activity GO:0071900 157 0.058
homeostasis of number of cells GO:0048872 210 0.058
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.058
regulation of cell cycle GO:0051726 281 0.058
forebrain development GO:0030900 302 0.058
tube formation GO:0035148 140 0.057
leukocyte mediated immunity GO:0002443 174 0.057
negative regulation of nervous system development GO:0051961 156 0.056
ear morphogenesis GO:0042471 118 0.056
Mouse
positive regulation of mesenchymal cell proliferation GO:0002053 33 0.056
regulation of neuron apoptotic process GO:0043523 122 0.056
endothelium development GO:0003158 45 0.056
regulation of systemic arterial blood pressure GO:0003073 61 0.055
Mouse
hematopoietic progenitor cell differentiation GO:0002244 143 0.055
cell fate commitment GO:0045165 210 0.055
neuron apoptotic process GO:0051402 142 0.055
metanephric epithelium development GO:0072207 21 0.054
atrioventricular valve morphogenesis GO:0003181 13 0.054
regulation of ossification GO:0030278 112 0.054
Mouse
t cell activation GO:0042110 289 0.054
positive regulation of mapk cascade GO:0043410 170 0.054
regulation of apoptotic signaling pathway GO:2001233 197 0.054
retina development in camera type eye GO:0060041 119 0.053
regulation of skeletal muscle fiber development GO:0048742 36 0.053
coronary vasculature development GO:0060976 12 0.053
regulation of establishment of protein localization GO:0070201 181 0.053
Mouse
phosphatidylinositol mediated signaling GO:0048015 41 0.052
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.052
negative regulation of wnt signaling pathway GO:0030178 73 0.051
response to acid chemical GO:0001101 111 0.051
central nervous system neuron differentiation GO:0021953 162 0.051
biomineral tissue development GO:0031214 64 0.051
Mouse
male gamete generation GO:0048232 285 0.050
response to molecule of bacterial origin GO:0002237 143 0.050
response to organic cyclic compound GO:0014070 198 0.050
cellular response to acid chemical GO:0071229 68 0.050
endocardial cell differentiation GO:0060956 4 0.049
epithelial cell migration GO:0010631 63 0.049
cochlea development GO:0090102 35 0.049
positive regulation of cellular amine metabolic process GO:0033240 5 0.049
detection of mechanical stimulus involved in equilibrioception GO:0050973 2 0.049
negative regulation of cell development GO:0010721 169 0.049
germ cell development GO:0007281 185 0.049
diencephalon development GO:0021536 63 0.049
bone morphogenesis GO:0060349 78 0.049
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.049
hormone metabolic process GO:0042445 86 0.049
inner ear morphogenesis GO:0042472 101 0.048
synaptic transmission GO:0007268 329 0.048
Mouse
molting cycle GO:0042303 90 0.048
detection of external stimulus GO:0009581 61 0.047
Mouse
regulation of cell size GO:0008361 72 0.047
axon guidance GO:0007411 141 0.047
regulation of ion transport GO:0043269 215 0.047
Mouse
negative regulation of phospholipase activity GO:0010519 4 0.047
regulation of neural precursor cell proliferation GO:2000177 70 0.046
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.046
nephron morphogenesis GO:0072028 69 0.046
positive regulation of neuroblast proliferation GO:0002052 19 0.046
regulation of kidney development GO:0090183 40 0.046
negative regulation of mesodermal cell fate specification GO:0042662 3 0.046
innate immune response GO:0045087 157 0.046
cell maturation GO:0048469 127 0.046
Mouse
negative regulation of cell proliferation GO:0008285 296 0.046
embryonic epithelial tube formation GO:0001838 130 0.046
regulation of stem cell division GO:2000035 4 0.046
regulation of auditory receptor cell differentiation GO:0045607 4 0.045
cartilage development GO:0051216 140 0.045
endochondral bone morphogenesis GO:0060350 50 0.045
tissue homeostasis GO:0001894 115 0.045
positive regulation of cytokine production GO:0001819 174 0.045
cytokine secretion GO:0050663 72 0.044
negative regulation of myoblast differentiation GO:0045662 18 0.044
regulation of bmp signaling pathway GO:0030510 60 0.044
endothelial cell differentiation GO:0045446 41 0.044
kidney morphogenesis GO:0060993 83 0.044
negative regulation of wnt signaling pathway involved in heart development GO:0003308 4 0.044
regulation of transcription involved in primary germ layer cell fate commitment GO:0060796 2 0.044
dna metabolic process GO:0006259 303 0.043
spinal cord motor neuron differentiation GO:0021522 35 0.043
amine metabolic process GO:0009308 45 0.043
negative regulation of angiogenesis GO:0016525 25 0.043
morphogenesis of a branching epithelium GO:0061138 193 0.043
negative regulation of cell activation GO:0050866 111 0.043
mesoderm formation GO:0001707 62 0.043
limb morphogenesis GO:0035108 149 0.043
Mouse
telencephalon development GO:0021537 186 0.043
positive regulation of kidney development GO:0090184 28 0.043
regulation of cellular component size GO:0032535 121 0.042
epithelial cell development GO:0002064 159 0.042
Mouse
protein localization to nucleus GO:0034504 121 0.042
positive regulation of muscle tissue development GO:1901863 32 0.042
Mouse
negative regulation of synapse maturation GO:2000297 2 0.042
regulation of cardiac cell fate specification GO:2000043 1 0.042
coronary artery morphogenesis GO:0060982 6 0.042
mesenchymal cell proliferation GO:0010463 44 0.042
cell surface receptor signaling pathway involved in heart development GO:0061311 15 0.042
negative regulation of phosphate metabolic process GO:0045936 184 0.042
positive regulation of metanephric mesenchymal cell migration GO:2000591 1 0.041
regulation of fat cell differentiation GO:0045598 81 0.041
establishment or maintenance of cell polarity GO:0007163 86 0.041
negative regulation of cellular protein metabolic process GO:0032269 247 0.041
liver development GO:0001889 66 0.041
myotube differentiation GO:0014902 105 0.041
cellular response to organonitrogen compound GO:0071417 145 0.041
nitrogen compound transport GO:0071705 271 0.041
blastocyst development GO:0001824 80 0.041
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 30 0.040
cell migration involved in gastrulation GO:0042074 13 0.040
formation of primary germ layer GO:0001704 77 0.040
vascular process in circulatory system GO:0003018 62 0.040
Mouse
cellular response to external stimulus GO:0071496 88 0.040
regulation of mesonephros development GO:0061217 24 0.040
regulation of mesenchymal cell proliferation GO:0010464 37 0.039
germ line sex determination GO:0018992 3 0.039
cardiac muscle cell differentiation GO:0055007 69 0.039
protein catabolic process GO:0030163 221 0.039
ventral spinal cord development GO:0021517 48 0.039
calcium ion homeostasis GO:0055074 127 0.039
glomerulus development GO:0032835 40 0.039
inner ear receptor cell differentiation GO:0060113 61 0.039
metanephric glomerular mesangial cell proliferation involved in metanephros development GO:0072262 3 0.039
cellular amine metabolic process GO:0044106 44 0.039
response to epidermal growth factor GO:0070849 4 0.039
epithelial structure maintenance GO:0010669 9 0.039
odontogenesis GO:0042476 78 0.039
inositol lipid mediated signaling GO:0048017 41 0.039
positive regulation of organelle organization GO:0010638 128 0.039
negative regulation of endothelial cell migration GO:0010596 4 0.038
myeloid cell differentiation GO:0030099 233 0.038
ventricular cardiac muscle tissue development GO:0003229 38 0.038
myeloid cell homeostasis GO:0002262 114 0.038
cardiac atrium development GO:0003230 24 0.038
Mouse
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.038
heart valve formation GO:0003188 10 0.037
heart valve development GO:0003170 23 0.037
skeletal system development GO:0001501 356 0.037
Mouse
response to transforming growth factor beta GO:0071559 88 0.037
gonad development GO:0008406 141 0.037
b cell differentiation GO:0030183 78 0.037
cardiogenic plate morphogenesis GO:0003142 1 0.037
branching morphogenesis of an epithelial tube GO:0048754 159 0.037
determination of left right symmetry GO:0007368 80 0.037
Mouse
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.037
endoderm development GO:0007492 45 0.037
regulation of embryonic development GO:0045995 71 0.037
platelet derived growth factor receptor beta signaling pathway GO:0035791 4 0.037
placenta development GO:0001890 140 0.036
Mouse
connective tissue development GO:0061448 179 0.036
trophoblast giant cell differentiation GO:0060707 15 0.036
positive regulation of apoptotic process GO:0043065 217 0.036
positive regulation of hormone secretion GO:0046887 38 0.036
chondrocyte hypertrophy GO:0003415 4 0.036
bone mineralization GO:0030282 54 0.036
Mouse
cellular response to epidermal growth factor stimulus GO:0071364 4 0.036
protein oligomerization GO:0051259 67 0.035
positive regulation of cell death GO:0010942 224 0.035
positive regulation of smooth muscle cell migration GO:0014911 4 0.035
negative regulation of blood vessel morphogenesis GO:2000181 25 0.035
intracellular protein transport GO:0006886 204 0.035
regulation of neuroblast proliferation GO:1902692 27 0.035
metanephric nephron tubule development GO:0072234 16 0.035
regulation of cellular response to growth factor stimulus GO:0090287 82 0.035
cardiac septum morphogenesis GO:0060411 46 0.035
Mouse
skeletal muscle cell differentiation GO:0035914 66 0.035
embryonic camera type eye development GO:0031076 36 0.035
renal system process GO:0003014 48 0.035
Mouse
metanephric glomerular mesangium development GO:0072223 3 0.034
mitotic cell cycle GO:0000278 195 0.034
developmental induction GO:0031128 34 0.034
regulation of cytokine production GO:0001817 266 0.034
endocardium formation GO:0060214 4 0.034
prostate gland morphogenetic growth GO:0060737 4 0.034
cardiac atrium morphogenesis GO:0003209 23 0.034
Mouse
protein localization to organelle GO:0033365 185 0.034
regulation of cytokine secretion GO:0050707 61 0.034
ovulation cycle GO:0042698 59 0.034
circadian rhythm GO:0007623 114 0.034
embryonic heart tube development GO:0035050 65 0.034
Mouse
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 20 0.034
lung epithelium development GO:0060428 37 0.033
carbohydrate homeostasis GO:0033500 128 0.033
regulation of hydrolase activity GO:0051336 246 0.033
somitogenesis GO:0001756 69 0.033
posttranscriptional regulation of gene expression GO:0010608 155 0.033
positive regulation of programmed cell death GO:0043068 218 0.033
t cell differentiation in thymus GO:0033077 77 0.033
positive regulation of cell activation GO:0050867 158 0.033
positive regulation of cell cycle GO:0045787 92 0.033
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 3 0.033
cardiac cell fate specification GO:0060912 2 0.033
pigmentation GO:0043473 71 0.033
regulation of endothelial cell migration GO:0010594 22 0.033
morphogenesis of a polarized epithelium GO:0001738 37 0.033
anatomical structure homeostasis GO:0060249 145 0.033
response to organonitrogen compound GO:0010243 246 0.032
regulation of mesenchymal cell proliferation involved in ureter development GO:0072199 3 0.032
eye photoreceptor cell differentiation GO:0001754 41 0.032
negative regulation of fat cell differentiation GO:0045599 36 0.032
metanephric glomerulus development GO:0072224 13 0.032
lymphocyte proliferation GO:0046651 164 0.032
bmp signaling pathway GO:0030509 93 0.032
gland development GO:0048732 330 0.032
lung smooth muscle development GO:0061145 2 0.032
epithelium migration GO:0090132 63 0.031
cellular ion homeostasis GO:0006873 165 0.031
compound eye development GO:0048749 1 0.031
telencephalon cell migration GO:0022029 55 0.031
positive regulation of lens epithelial cell proliferation GO:2001111 1 0.031
endothelial cell apoptotic process GO:0072577 9 0.031
glomerular mesangial cell development GO:0072144 3 0.031
regulation of organelle organization GO:0033043 289 0.031
regulation of homeostatic process GO:0032844 182 0.031
Mouse
positive regulation of satellite cell activation involved in skeletal muscle regeneration GO:0014718 2 0.031
regulation of morphogenesis of a branching structure GO:0060688 53 0.031
negative regulation of protein modification process GO:0031400 163 0.031
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.031
epithelial to mesenchymal transition GO:0001837 47 0.031
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.031
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 26 0.031
positive regulation of mechanoreceptor differentiation GO:0045633 1 0.031
negative regulation of osteoblast differentiation GO:0045668 30 0.030
positive regulation of insulin secretion GO:0032024 26 0.030
tendon formation GO:0035992 4 0.030
regulation of intestinal epithelial structure maintenance GO:0060730 1 0.030
response to retinoic acid GO:0032526 56 0.030
regulation of lens epithelial cell proliferation GO:2001109 1 0.030
negative regulation of neuron differentiation GO:0045665 101 0.030
positive regulation of behavior GO:0048520 40 0.030
negative regulation of cellular amine metabolic process GO:0033239 1 0.030
negative regulation of phosphorus metabolic process GO:0010563 184 0.030
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.030
adaptive immune response GO:0002250 155 0.030
positive regulation of extracellular matrix organization GO:1903055 4 0.029
aorta morphogenesis GO:0035909 22 0.029
peptidyl tyrosine phosphorylation GO:0018108 143 0.029
closure of optic fissure GO:0061386 2 0.029
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.029
monocarboxylic acid metabolic process GO:0032787 191 0.029
development of primary male sexual characteristics GO:0046546 88 0.029
spermatogenesis GO:0007283 284 0.029
mesenchyme morphogenesis GO:0072132 32 0.029
regulation of epithelial cell migration GO:0010632 35 0.029
mesangial cell differentiation GO:0072007 4 0.029
regulation of neuron death GO:1901214 134 0.029
regulation of cell cycle process GO:0010564 160 0.028
negative regulation of cell fate specification GO:0009996 4 0.028
negative regulation of ossification GO:0030279 49 0.028
detection of mechanical stimulus involved in sensory perception of sound GO:0050910 16 0.028
male sex differentiation GO:0046661 109 0.028
membrane organization GO:0061024 245 0.028
ribose phosphate metabolic process GO:0019693 291 0.028
developmental growth involved in morphogenesis GO:0060560 138 0.028
negative regulation of photoreceptor cell differentiation GO:0046533 4 0.028
protein kinase b signaling GO:0043491 74 0.028
heart process GO:0003015 94 0.028
Mouse
notochord development GO:0030903 20 0.028
response to heparin GO:0071503 1 0.028
negative regulation of embryonic development GO:0045992 22 0.028
organelle localization GO:0051640 179 0.028
purine containing compound metabolic process GO:0072521 311 0.028
regulation of lipid metabolic process GO:0019216 118 0.028
lymphocyte mediated immunity GO:0002449 139 0.027
regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathway GO:1900238 1 0.027
hormone secretion GO:0046879 128 0.027
endocardial cushion morphogenesis GO:0003203 18 0.027
equilibrioception GO:0050957 3 0.027
ventricular cardiac muscle tissue morphogenesis GO:0055010 32 0.027
regulation of reactive oxygen species metabolic process GO:2000377 40 0.027
neuromuscular process GO:0050905 99 0.027

Gja4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.081
cardiovascular system disease DOID:1287 0 0.081
nervous system disease DOID:863 0 0.035
heart disease DOID:114 0 0.030