|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.922
|
Rat |
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.902
|
Rat |
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.836
|
Mouse |
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.809
|
Rat |
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.798
|
Rat |
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.795
|
Rat |
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.779
|
Rat |
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.746
|
Rat |
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.735
|
Rat |
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.723
|
Rat |
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.723
|
Rat |
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
91 |
0.712
|
Rat |
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.697
|
Rat |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.694
|
Rat |
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.685
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.664
|
Rat |
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.660
|
Rat |
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.643
|
Rat |
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.625
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.622
|
Rat |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.616
|
Mouse |
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
88 |
0.613
|
Rat |
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.598
|
Rat |
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.591
|
Rat |
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.584
|
Rat |
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.581
|
Rat |
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.576
|
Fly |
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.572
|
Rat |
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
88 |
0.567
|
Rat |
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.567
|
Rat |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.564
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.563
|
Rat |
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.553
|
Rat |
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.549
|
Rat |
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.547
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.544
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.541
|
Rat |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.526
|
Rat |
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.525
|
Rat |
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.520
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.514
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.511
|
Rat |
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.497
|
Mouse Rat Fly |
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.494
|
Rat |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.473
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.473
|
Rat |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.470
|
Fly |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.467
|
Fly |
|
|
activation of immune response
|
GO:0002253 |
138 |
0.467
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.465
|
Fly |
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.449
|
Rat |
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.447
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.445
|
Rat |
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.440
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.428
|
Fly |
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.425
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.413
|
Rat |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.408
|
Rat |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.407
|
Rat |
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.404
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.402
|
Rat |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.392
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.367
|
Rat |
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.365
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.362
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.359
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
34 |
0.356
|
Fly |
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.354
|
Rat Fly |
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.347
|
Mouse Rat |
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.339
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.334
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.333
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.329
|
Human Rat Fly |
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.328
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.327
|
Rat |
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
42 |
0.321
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.321
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.321
|
Rat |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.320
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.317
|
Rat |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.312
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.311
|
Fly |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.308
|
Human Rat |
|
|
actin polymerization or depolymerization
|
GO:0008154 |
54 |
0.306
|
Human |
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.306
|
Mouse Rat |
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.305
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.302
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.301
|
Rat Fly |
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.297
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.294
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.292
|
Fly |
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.285
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.284
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.283
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.279
|
|
|
|
peptidyl serine autophosphorylation
|
GO:0036289 |
1 |
0.271
|
|
|
|
regulation of insulin receptor signaling pathway
|
GO:0046626 |
21 |
0.271
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.270
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.262
|
|
|
|
positive regulation of b cell receptor signaling pathway
|
GO:0050861 |
4 |
0.261
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.258
|
Rat |
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.257
|
Rat |
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.255
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.255
|
Human Rat |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.255
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.252
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.249
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.247
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.246
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
41 |
0.244
|
Rat |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.243
|
Rat |
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.237
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.232
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.228
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.225
|
Rat |
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.224
|
Rat |
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.222
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.220
|
Fly |
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.218
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.213
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.211
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.206
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.202
|
Rat |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.199
|
Rat |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.198
|
|
|
|
memory
|
GO:0007613 |
58 |
0.197
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.197
|
|
|
|
positive regulation of actin filament polymerization
|
GO:0030838 |
26 |
0.197
|
Human |
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.196
|
Fly |
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
25 |
0.195
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.195
|
|
|
|
associative learning
|
GO:0008306 |
61 |
0.195
|
|
|
|
regulation of calcium ion transport into cytosol
|
GO:0010522 |
31 |
0.194
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.193
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.187
|
Mouse Fly |
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.186
|
|
|
|
regulation of neuronal synaptic plasticity
|
GO:0048168 |
30 |
0.183
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.181
|
Fly |
|
|
gland development
|
GO:0048732 |
330 |
0.173
|
|
|
|
cilium morphogenesis
|
GO:0060271 |
102 |
0.171
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.170
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.168
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.166
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.165
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.164
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.162
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
78 |
0.161
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
45 |
0.160
|
Human |
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.159
|
Fly |
|
|
negative regulation of insulin receptor signaling pathway
|
GO:0046627 |
14 |
0.158
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.158
|
|
|
|
monosaccharide transport
|
GO:0015749 |
58 |
0.158
|
|
|
|
cellular response to ethanol
|
GO:0071361 |
3 |
0.158
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.156
|
Human |
|
|
learning
|
GO:0007612 |
98 |
0.156
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.155
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.152
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
87 |
0.151
|
Rat |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.148
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.147
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.145
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.145
|
|
|
|
b cell receptor signaling pathway
|
GO:0050853 |
20 |
0.145
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.144
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.143
|
Human Rat Fly |
|
|
cation transport
|
GO:0006812 |
399 |
0.142
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.142
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.142
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.141
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.141
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.140
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.137
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.137
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.137
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.134
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.133
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
74 |
0.133
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.132
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.132
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.132
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.131
|
Mouse |
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.130
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.129
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.129
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.129
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.127
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.126
|
Rat |
|
|
toll like receptor signaling pathway
|
GO:0002224 |
38 |
0.126
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.124
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
65 |
0.123
|
Rat |
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.121
|
Mouse Fly |
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.121
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.120
|
|
|
|
detection of mechanical stimulus involved in sensory perception of pain
|
GO:0050966 |
4 |
0.119
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.119
|
Human |
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.119
|
Rat |
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.119
|
|
|
|
olfactory learning
|
GO:0008355 |
2 |
0.118
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.117
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.117
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.115
|
|
|
|
long term synaptic potentiation
|
GO:0060291 |
25 |
0.115
|
Rat |
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.114
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.114
|
Human Mouse Fly |
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.114
|
|
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.114
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.113
|
Mouse |
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.113
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.111
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.111
|
Human |
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.111
|
|
|
|
response to insulin
|
GO:0032868 |
100 |
0.109
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.109
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.109
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.106
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.104
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.103
|
Fly |
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.103
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.102
|
|
|
|
toll like receptor 4 signaling pathway
|
GO:0034142 |
9 |
0.102
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.102
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.102
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.101
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.099
|
Human Rat |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.099
|
|
|
|
insulin receptor signaling pathway
|
GO:0008286 |
49 |
0.099
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.098
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.098
|
Mouse Fly |
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.098
|
Human |
|
|
cellularization
|
GO:0007349 |
1 |
0.098
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.098
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.097
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.097
|
|
|
|
regulation of homotypic cell cell adhesion
|
GO:0034110 |
13 |
0.097
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
69 |
0.096
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.096
|
|
|
|
carbohydrate transport
|
GO:0008643 |
62 |
0.094
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.093
|
|
|
|
negative regulation of cellular response to insulin stimulus
|
GO:1900077 |
16 |
0.092
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.092
|
Human |
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.092
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.092
|
|
|
|
regulation of blood coagulation
|
GO:0030193 |
28 |
0.092
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.090
|
|
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
34 |
0.090
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.090
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.090
|
Human |
|
|
muscle contraction
|
GO:0006936 |
101 |
0.090
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.089
|
|
|
|
actin filament polymerization
|
GO:0030041 |
44 |
0.089
|
Human |
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.089
|
|
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
14 |
0.088
|
Rat |
|
|
oocyte axis specification
|
GO:0007309 |
2 |
0.088
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.088
|
|
|
|
response to ethanol
|
GO:0045471 |
18 |
0.087
|
Rat |
|
|
activation of meiosis
|
GO:0090427 |
4 |
0.087
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.086
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.085
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.085
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.085
|
Human |
|
|
homotypic cell cell adhesion
|
GO:0034109 |
28 |
0.084
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.084
|
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.083
|
|
|
|
mast cell proliferation
|
GO:0070662 |
4 |
0.083
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.082
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.082
|
Human |
|
|
oocyte construction
|
GO:0007308 |
2 |
0.082
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.082
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.081
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.081
|
Mouse |
|
|
glucose transport
|
GO:0015758 |
56 |
0.080
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.080
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.080
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
79 |
0.080
|
Human |
|
|
response to peptide
|
GO:1901652 |
136 |
0.079
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.079
|
|
|
|
platelet aggregation
|
GO:0070527 |
20 |
0.078
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.078
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
45 |
0.078
|
Human |
|
|
wound healing
|
GO:0042060 |
157 |
0.078
|
|
|
|
negative regulation of toll like receptor signaling pathway
|
GO:0034122 |
14 |
0.078
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.077
|
Human Mouse |
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.077
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.077
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.077
|
Mouse |
|
|
regionalization
|
GO:0003002 |
337 |
0.077
|
|
|
|
adherens junction organization
|
GO:0034332 |
28 |
0.076
|
Rat |
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.076
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.075
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.075
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.075
|
Human |
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.074
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
40 |
0.074
|
Rat |
|
|
cell cell junction organization
|
GO:0045216 |
72 |
0.074
|
Rat |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.073
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.073
|
|
|
|
myd88 independent toll like receptor signaling pathway
|
GO:0002756 |
3 |
0.073
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.073
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.073
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.072
|
Human |
|
|
regulation of toll like receptor 4 signaling pathway
|
GO:0034143 |
4 |
0.071
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.071
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.070
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.070
|
Human |
|
|
long term memory
|
GO:0007616 |
15 |
0.069
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.069
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.069
|
|
|
|
hexose transport
|
GO:0008645 |
56 |
0.068
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.068
|
|
|
|
regulation of actin filament polymerization
|
GO:0030833 |
38 |
0.068
|
Human |
|
|
t cell mediated immunity
|
GO:0002456 |
50 |
0.067
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.067
|
Fly |
|
|
cell maturation
|
GO:0048469 |
127 |
0.067
|
Rat |
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.066
|
|
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
36 |
0.066
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.066
|
|
|
|
oocyte development
|
GO:0048599 |
33 |
0.065
|
Rat |
|
|
neutrophil migration
|
GO:1990266 |
37 |
0.065
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.065
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.065
|
|
|
|
response to ammonium ion
|
GO:0060359 |
21 |
0.065
|
Rat |
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.065
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.065
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.064
|
|
|
|
heart process
|
GO:0003015 |
94 |
0.064
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.063
|
|
|
|
hemostasis
|
GO:0007599 |
78 |
0.063
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.063
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.062
|
Human |
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.062
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.062
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.062
|
Human |
|
|
positive regulation of podosome assembly
|
GO:0071803 |
3 |
0.062
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
74 |
0.061
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.061
|
|
|
|
cell junction assembly
|
GO:0034329 |
52 |
0.061
|
Rat |
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.060
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.060
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.060
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.060
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.059
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.059
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
58 |
0.059
|
Rat |
|
|
response to reactive oxygen species
|
GO:0000302 |
56 |
0.059
|
Rat |
|
|
dense core granule biogenesis
|
GO:0061110 |
1 |
0.059
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.059
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.059
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.058
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.058
|
|
|
|
response to alcohol
|
GO:0097305 |
48 |
0.058
|
Rat |
|
|
negative regulation of ras protein signal transduction
|
GO:0046580 |
18 |
0.058
|
Mouse |
|
|
regulation of protein processing
|
GO:0070613 |
96 |
0.058
|
|
|
|
regulation of mast cell proliferation
|
GO:0070666 |
4 |
0.058
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.057
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.057
|
Human |
|
|
negative regulation of peptidyl tyrosine phosphorylation
|
GO:0050732 |
17 |
0.057
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.057
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.057
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.056
|
Human |
|
|
hormone secretion
|
GO:0046879 |
128 |
0.056
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.056
|
Mouse |
|
|
coagulation
|
GO:0050817 |
78 |
0.056
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.056
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.056
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.055
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
79 |
0.055
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.055
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
79 |
0.055
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.054
|
Human Mouse |
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.054
|
Rat |
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.054
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.053
|
|
|
|
protein oligomerization
|
GO:0051259 |
67 |
0.053
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.053
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.053
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
86 |
0.053
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.053
|
|
|
|
glucose import
|
GO:0046323 |
32 |
0.052
|
|
|
|
oocyte differentiation
|
GO:0009994 |
35 |
0.052
|
Rat |
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.052
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.052
|
|
|
|
regulation of platelet activation
|
GO:0010543 |
17 |
0.051
|
|
|
|
regulation of g protein coupled receptor protein signaling pathway
|
GO:0008277 |
37 |
0.051
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.050
|
Rat |
|
|
regulation of binding
|
GO:0051098 |
111 |
0.050
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.050
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.050
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.050
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.049
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.049
|
Mouse |
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.049
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.049
|
Rat |
|
|
positive regulation of gamma delta t cell differentiation
|
GO:0045588 |
6 |
0.049
|
|
|
|
establishment of vesicle localization
|
GO:0051650 |
81 |
0.049
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.049
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
54 |
0.049
|
Rat |
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.049
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.049
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.048
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.047
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.047
|
Rat |
|
|
cell junction organization
|
GO:0034330 |
77 |
0.047
|
Rat |
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.047
|
Rat |
|
|
regulation of toll like receptor 2 signaling pathway
|
GO:0034135 |
3 |
0.047
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.047
|
|
|
|
regulation of receptor activity
|
GO:0010469 |
41 |
0.047
|
Rat |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.047
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.046
|
|
|
|
regulation of cellular response to insulin stimulus
|
GO:1900076 |
30 |
0.046
|
|
|
|
regulation of toll like receptor signaling pathway
|
GO:0034121 |
20 |
0.046
|
|
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.045
|
|
|
|
pole plasm assembly
|
GO:0007315 |
2 |
0.045
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.045
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.045
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.045
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.045
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.045
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.045
|
|
|
|
oocyte anterior posterior axis specification
|
GO:0007314 |
2 |
0.045
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.045
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.044
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.044
|
Rat |
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.044
|
|
|
|
synaptic transmission gabaergic
|
GO:0051932 |
19 |
0.044
|
|
|
|
regulation of podosome assembly
|
GO:0071801 |
3 |
0.044
|
|
|
|
cellular glucose homeostasis
|
GO:0001678 |
52 |
0.044
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.044
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.044
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.043
|
Human |
|
|
germ cell development
|
GO:0007281 |
185 |
0.043
|
Rat |
|
|
smooth muscle contraction
|
GO:0006939 |
44 |
0.043
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.043
|
Rat |
|
|
positive regulation of synaptic growth at neuromuscular junction
|
GO:0045887 |
1 |
0.043
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
65 |
0.042
|
|
|
|
vesicle organization
|
GO:0016050 |
60 |
0.042
|
|
|
|
regulation of erythrocyte differentiation
|
GO:0045646 |
23 |
0.042
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.042
|
|
|
|
maternal determination of anterior posterior axis embryo
|
GO:0008358 |
2 |
0.041
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.041
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.041
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.041
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.041
|
Rat |
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.041
|
Human |
|
|
regulation of synaptic transmission gabaergic
|
GO:0032228 |
17 |
0.040
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.040
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.040
|
|
|
|
neuromuscular process
|
GO:0050905 |
99 |
0.040
|
|
|
|
gamma delta t cell differentiation
|
GO:0042492 |
11 |
0.039
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.039
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.039
|
|
|
|
neuron neuron synaptic transmission
|
GO:0007270 |
69 |
0.039
|
Rat |
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.039
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.039
|
|
|
|
autophagy
|
GO:0006914 |
45 |
0.039
|
|
|
|
epidermal growth factor receptor signaling pathway
|
GO:0007173 |
28 |
0.039
|
Rat Fly |
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.039
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.038
|
|
|
|
detection of stimulus
|
GO:0051606 |
84 |
0.038
|
|
|
|
regulation of cell division
|
GO:0051302 |
76 |
0.038
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.038
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.037
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
98 |
0.037
|
Rat |
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.037
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.037
|
|
|
|
regulation of glucose transport
|
GO:0010827 |
32 |
0.037
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.037
|
|
|
|
synaptic vesicle transport
|
GO:0048489 |
57 |
0.037
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
65 |
0.037
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.037
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.037
|
Human |
|
|
cell junction maintenance
|
GO:0034331 |
4 |
0.037
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.036
|
|
|
|
detection of stimulus involved in sensory perception
|
GO:0050906 |
44 |
0.036
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.036
|
|
|
|
protein localization to cell junction
|
GO:1902414 |
3 |
0.036
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
71 |
0.036
|
|
|
|
glutamate receptor signaling pathway
|
GO:0007215 |
35 |
0.036
|
Rat |
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.035
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.035
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.035
|
Mouse |
|
|
regulation of transporter activity
|
GO:0032409 |
57 |
0.035
|
Rat |
|
|
regulation of b cell receptor signaling pathway
|
GO:0050855 |
9 |
0.035
|
|
|
|
multicellular organismal response to stress
|
GO:0033555 |
62 |
0.035
|
|
|
|
labyrinthine layer development
|
GO:0060711 |
49 |
0.035
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.035
|
Rat |
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.034
|
|
|
|
response to alkaloid
|
GO:0043279 |
34 |
0.034
|
Rat |
|
|
regulation of vasculature development
|
GO:1901342 |
88 |
0.034
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.034
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
68 |
0.034
|
Human |
|
|
regulation of protein binding
|
GO:0043393 |
60 |
0.034
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.034
|
|
|
|
negative regulation of erk1 and erk2 cascade
|
GO:0070373 |
21 |
0.034
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.034
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.034
|
|
