Mus musculus

0 known processes

Isg20

interferon-stimulated protein

(Aliases: 1600023I01Rik,2010107M23Rik,DnaQL,HEM45,20kDa)

Isg20 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of viral genome replication GO:0045071 10 0.512
Human
viral process GO:0016032 41 0.097
Human
negative regulation of cell proliferation GO:0008285 296 0.076
apoptotic signaling pathway GO:0097190 306 0.076
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.067
Human
interspecies interaction between organisms GO:0044419 83 0.066
Human
activation of immune response GO:0002253 138 0.063
cytokine production GO:0001816 319 0.057
regulation of t helper 2 cell cytokine production GO:2000551 3 0.056
positive regulation of cellular amine metabolic process GO:0033240 5 0.054
regulation of cytokine production GO:0001817 266 0.053
regulation of cellular amino acid metabolic process GO:0006521 5 0.052
leukocyte differentiation GO:0002521 342 0.051
myeloid cell differentiation GO:0030099 233 0.050
myeloid cell homeostasis GO:0002262 114 0.050
homeostasis of number of cells GO:0048872 210 0.047
lymphocyte differentiation GO:0030098 242 0.047
pattern recognition receptor signaling pathway GO:0002221 47 0.047
viral life cycle GO:0019058 36 0.043
Human
cation transport GO:0006812 399 0.042
cellular amine metabolic process GO:0044106 44 0.040
immune response activating signal transduction GO:0002757 116 0.039
defense response to virus GO:0051607 68 0.039
Human
cellular ketone metabolic process GO:0042180 84 0.038
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.038
negative regulation of multi organism process GO:0043901 68 0.038
Human
cell type specific apoptotic process GO:0097285 268 0.038
regulation of cellular amine metabolic process GO:0033238 20 0.038
striated muscle tissue development GO:0014706 293 0.038
cellular homeostasis GO:0019725 240 0.037
regulation of cellular ketone metabolic process GO:0010565 66 0.037
myeloid leukocyte differentiation GO:0002573 119 0.037
divalent metal ion transport GO:0070838 172 0.037
fat cell differentiation GO:0045444 160 0.036
t helper 2 cell cytokine production GO:0035745 4 0.036
regulation of homeostatic process GO:0032844 182 0.036
immune effector process GO:0002252 321 0.036
Human
macromolecule catabolic process GO:0009057 281 0.035
Human
cellular macromolecule catabolic process GO:0044265 206 0.035
Human
regulation of multi organism process GO:0043900 111 0.034
Human
cellular amino acid metabolic process GO:0006520 103 0.034
positive regulation of programmed cell death GO:0043068 218 0.034
cellular chemical homeostasis GO:0055082 215 0.033
regulation of cellular component biogenesis GO:0044087 181 0.033
regulation of secretion by cell GO:1903530 249 0.032
innate immune response GO:0045087 157 0.031
regulation of t cell activation GO:0050863 170 0.031
cellular metal ion homeostasis GO:0006875 151 0.031
carbohydrate metabolic process GO:0005975 230 0.031
heterocycle catabolic process GO:0046700 280 0.031
Human
muscle tissue development GO:0060537 308 0.030
response to organic cyclic compound GO:0014070 198 0.030
immune response regulating signaling pathway GO:0002764 125 0.029
positive regulation of cytokine production GO:0001819 174 0.029
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.029
cellular response to lipid GO:0071396 145 0.028
amine metabolic process GO:0009308 45 0.028
calcium ion transport GO:0006816 159 0.028
negative regulation of protein metabolic process GO:0051248 282 0.028
cellular ion homeostasis GO:0006873 165 0.028
ossification GO:0001503 216 0.028
modification dependent macromolecule catabolic process GO:0043632 133 0.028
regulation of cell activation GO:0050865 289 0.027
positive regulation of cell death GO:0010942 224 0.026
negative regulation of viral process GO:0048525 23 0.026
Human
peptidyl amino acid modification GO:0018193 336 0.026
ion transmembrane transport GO:0034220 361 0.026
covalent chromatin modification GO:0016569 163 0.025
maintenance of location GO:0051235 89 0.025
carbohydrate derivative biosynthetic process GO:1901137 183 0.025
protein secretion GO:0009306 111 0.025
divalent inorganic cation transport GO:0072511 178 0.025
ras protein signal transduction GO:0007265 77 0.024
regulation of innate immune response GO:0045088 91 0.024
skeletal muscle organ development GO:0060538 163 0.024
t cell differentiation GO:0030217 174 0.024
histone modification GO:0016570 159 0.024
metal ion homeostasis GO:0055065 189 0.024
posttranscriptional regulation of gene expression GO:0010608 155 0.024
positive regulation of apoptotic process GO:0043065 217 0.023
cellular nitrogen compound catabolic process GO:0044270 280 0.023
Human
intrinsic apoptotic signaling pathway GO:0097193 132 0.023
small molecule biosynthetic process GO:0044283 132 0.023
protein catabolic process GO:0030163 221 0.023
modification dependent protein catabolic process GO:0019941 133 0.022
alpha beta t cell differentiation GO:0046632 69 0.022
erythrocyte differentiation GO:0030218 88 0.022
spermatogenesis GO:0007283 284 0.022
glycoprotein metabolic process GO:0009100 116 0.022
purine containing compound metabolic process GO:0072521 311 0.022
transmembrane transport GO:0055085 412 0.022
organonitrogen compound biosynthetic process GO:1901566 192 0.022
intracellular protein transport GO:0006886 204 0.022
anion transport GO:0006820 177 0.022
organophosphate biosynthetic process GO:0090407 122 0.021
cytokine mediated signaling pathway GO:0019221 115 0.021
protein processing GO:0016485 163 0.021
chromatin organization GO:0006325 206 0.021
protein ubiquitination GO:0016567 171 0.021
germ cell development GO:0007281 185 0.020
regulation of leukocyte proliferation GO:0070663 121 0.020
regulation of organelle organization GO:0033043 289 0.020
cation homeostasis GO:0055080 212 0.020
protein acylation GO:0043543 64 0.020
regulation of lymphocyte activation GO:0051249 240 0.020
positive regulation of defense response GO:0031349 124 0.020
leukocyte activation involved in immune response GO:0002366 126 0.019
glycoprotein biosynthetic process GO:0009101 89 0.019
response to organonitrogen compound GO:0010243 246 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.019
compound eye development GO:0048749 1 0.019
interleukin 8 production GO:0032637 4 0.019
protein modification by small protein conjugation or removal GO:0070647 207 0.019
negative regulation of cellular protein metabolic process GO:0032269 247 0.019
cellular protein catabolic process GO:0044257 155 0.019
wound healing GO:0042060 157 0.019
epithelial tube morphogenesis GO:0060562 303 0.019
regulation of t cell proliferation GO:0042129 92 0.018
regulation of leukocyte differentiation GO:1902105 159 0.018
divalent inorganic cation homeostasis GO:0072507 138 0.018
innate immune response activating signal transduction GO:0002758 50 0.018
response to radiation GO:0009314 165 0.018
regulation of vesicle mediated transport GO:0060627 139 0.018
endomembrane system organization GO:0010256 147 0.017
cellular divalent inorganic cation homeostasis GO:0072503 127 0.017
protein modification by small protein conjugation GO:0032446 187 0.017
regulation of secretion GO:0051046 274 0.017
organic acid biosynthetic process GO:0016053 86 0.017
viral genome replication GO:0019079 17 0.017
Human
regulation of cell cycle GO:0051726 281 0.017
regulation of apoptotic signaling pathway GO:2001233 197 0.017
positive regulation of lymphocyte activation GO:0051251 140 0.017
regulation of protein localization GO:0032880 231 0.017
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.017
regulation of hydrolase activity GO:0051336 246 0.017
positive regulation of protein modification process GO:0031401 299 0.017
nucleobase containing small molecule metabolic process GO:0055086 352 0.017
regulation of defense response GO:0031347 233 0.017
nucleotide metabolic process GO:0009117 332 0.016
positive regulation of nucleotide metabolic process GO:0045981 114 0.016
male gamete generation GO:0048232 285 0.016
positive regulation of innate immune response GO:0045089 80 0.016
inflammatory response GO:0006954 244 0.016
interferon gamma production GO:0032609 67 0.016
carbohydrate derivative catabolic process GO:1901136 231 0.016
positive regulation of immune effector process GO:0002699 107 0.016
cellular lipid metabolic process GO:0044255 323 0.016
organelle assembly GO:0070925 177 0.016
organic cyclic compound catabolic process GO:1901361 295 0.016
Human
myeloid leukocyte activation GO:0002274 83 0.016
amide transport GO:0042886 138 0.016
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.016
regulation of ion transport GO:0043269 215 0.016
protein maturation GO:0051604 176 0.015
regulation of interleukin 8 production GO:0032677 3 0.015
monocarboxylic acid biosynthetic process GO:0072330 61 0.015
lipid biosynthetic process GO:0008610 179 0.015
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 35 0.015
regionalization GO:0003002 337 0.015
regulation of protein processing GO:0070613 96 0.015
negative regulation of growth GO:0045926 99 0.015
multicellular organismal signaling GO:0035637 91 0.015
nitrogen compound transport GO:0071705 271 0.015
carboxylic acid biosynthetic process GO:0046394 86 0.015
regulation of protein secretion GO:0050708 82 0.015
neuron death GO:0070997 154 0.015
adaptive immune response GO:0002250 155 0.015
negative regulation of molecular function GO:0044092 258 0.015
glycosyl compound metabolic process GO:1901657 246 0.015
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.015
g protein coupled receptor signaling pathway GO:0007186 243 0.015
translation GO:0006412 93 0.015
regulation of mapk cascade GO:0043408 248 0.015
positive regulation of cell development GO:0010720 237 0.015
regulation of membrane potential GO:0042391 192 0.015
fatty acid derivative biosynthetic process GO:1901570 15 0.015
activation of innate immune response GO:0002218 56 0.015
positive regulation of organelle organization GO:0010638 128 0.015
actin cytoskeleton organization GO:0030036 220 0.014
methylation GO:0032259 134 0.014
small gtpase mediated signal transduction GO:0007264 97 0.014
negative regulation of cell activation GO:0050866 111 0.014
gland development GO:0048732 330 0.014
regulation of protein transport GO:0051223 163 0.014
skin development GO:0043588 220 0.014
regulation of proteolysis GO:0030162 164 0.014
negative regulation of interferon beta production GO:0032688 3 0.014
synaptic transmission GO:0007268 329 0.014
sequestering of calcium ion GO:0051208 18 0.014
camera type eye development GO:0043010 266 0.014
inorganic ion transmembrane transport GO:0098660 234 0.014
chromatin modification GO:0016568 187 0.014
cellular response to cytokine stimulus GO:0071345 189 0.014
ribonucleoside catabolic process GO:0042454 206 0.014
cellular protein complex assembly GO:0043623 116 0.014
microglial cell activation involved in immune response GO:0002282 1 0.014
toll like receptor 7 signaling pathway GO:0034154 4 0.014
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.014
Human
positive regulation of cellular component biogenesis GO:0044089 94 0.014
mitotic cell cycle process GO:1903047 159 0.014
negative regulation of apoptotic signaling pathway GO:2001234 104 0.014
monocarboxylic acid metabolic process GO:0032787 191 0.014
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.014
regulation of protein complex assembly GO:0043254 83 0.014
microtubule cytoskeleton organization GO:0000226 157 0.014
response to inorganic substance GO:0010035 96 0.014
regulation of neuron death GO:1901214 134 0.014
negative regulation of proteolysis GO:0045861 74 0.014
regulation of ossification GO:0030278 112 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.013
cofactor metabolic process GO:0051186 80 0.013
response to acid chemical GO:0001101 111 0.013
spermatid development GO:0007286 108 0.013
rna interference GO:0016246 2 0.013
blood circulation GO:0008015 195 0.013
nucleoside phosphate metabolic process GO:0006753 338 0.013
blood vessel morphogenesis GO:0048514 285 0.013
fatty acid metabolic process GO:0006631 121 0.013
microtubule based process GO:0007017 236 0.013
cellular response to interferon alpha GO:0035457 4 0.013
protein methylation GO:0006479 81 0.013
locomotory behavior GO:0007626 195 0.013
epidermis development GO:0008544 187 0.013
negative regulation of cellular component organization GO:0051129 194 0.013
sequestering of metal ion GO:0051238 19 0.013
ear development GO:0043583 200 0.013
regulation of cell migration GO:0030334 219 0.013
ribose phosphate metabolic process GO:0019693 291 0.013
epithelial cell proliferation GO:0050673 174 0.013
fatty acid biosynthetic process GO:0006633 41 0.013
cellular response to hormone stimulus GO:0032870 150 0.013
cell activation involved in immune response GO:0002263 126 0.013
endocytosis GO:0006897 168 0.013
regulation of protein maturation GO:1903317 96 0.013
response to extracellular stimulus GO:0009991 127 0.013
positive regulation of adaptive immune response GO:0002821 61 0.013
lymphocyte proliferation GO:0046651 164 0.012
purine ribonucleoside metabolic process GO:0046128 241 0.012
regulation of body fluid levels GO:0050878 162 0.012
negative regulation of cytokine production GO:0001818 84 0.012
skeletal system development GO:0001501 356 0.012
transmission of nerve impulse GO:0019226 76 0.012
nucleoside triphosphate catabolic process GO:0009143 205 0.012
morphogenesis of a branching structure GO:0001763 203 0.012
regulation of adaptive immune response GO:0002819 90 0.012
negative regulation of protein maturation GO:1903318 79 0.012
muscle cell differentiation GO:0042692 261 0.012
regulation of hormone levels GO:0010817 211 0.012
regulation of establishment of protein localization GO:0070201 181 0.012
oxidation reduction process GO:0055114 342 0.012
purine ribonucleotide catabolic process GO:0009154 208 0.012
sensory perception GO:0007600 245 0.012
regulation of protein serine threonine kinase activity GO:0071900 157 0.012
cell adhesion GO:0007155 329 0.012
signal transduction by p53 class mediator GO:0072331 51 0.012
circulatory system process GO:0003013 197 0.012
ribonucleoside metabolic process GO:0009119 245 0.012
protein glycosylation GO:0006486 55 0.012
calcium ion homeostasis GO:0055074 127 0.012
reactive oxygen species metabolic process GO:0072593 84 0.012
purine nucleoside metabolic process GO:0042278 241 0.012
action potential GO:0001508 78 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.012
response to transforming growth factor beta GO:0071559 88 0.012
purine nucleotide metabolic process GO:0006163 302 0.012
circadian rhythm GO:0007623 114 0.012
release of sequestered calcium ion into cytosol GO:0051209 42 0.012
cellular component assembly involved in morphogenesis GO:0010927 139 0.012
cation transmembrane transport GO:0098655 266 0.012
regulation of binding GO:0051098 111 0.012
regulation of translation GO:0006417 71 0.012
positive regulation of cellular catabolic process GO:0031331 148 0.012
cytoplasmic transport GO:0016482 234 0.012
negative regulation of cellular amine metabolic process GO:0033239 1 0.012
mapk cascade GO:0000165 281 0.012
nucleoside phosphate catabolic process GO:1901292 222 0.012
t cell activation GO:0042110 289 0.012
angiogenesis GO:0001525 201 0.011
chemokine mediated signaling pathway GO:0070098 17 0.011
regulation of endocytosis GO:0030100 69 0.011
organophosphate catabolic process GO:0046434 232 0.011
mature dendritic cell differentiation GO:0097029 3 0.011
alpha beta t cell activation GO:0046631 91 0.011
regulation of cell motility GO:2000145 236 0.011
response to light stimulus GO:0009416 135 0.011
nucleoside catabolic process GO:0009164 206 0.011
positive regulation of neutrophil mediated killing of symbiont cell GO:0070961 1 0.011
regulation of cytokine biosynthetic process GO:0042035 59 0.011
nucleoside triphosphate metabolic process GO:0009141 230 0.011
development of primary male sexual characteristics GO:0046546 88 0.011
membrane organization GO:0061024 245 0.011
cd4 positive alpha beta t cell proliferation GO:0035739 2 0.011
negative regulation of defense response GO:0031348 77 0.011
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.011
protein polymerization GO:0051258 57 0.011
cellular response to dna damage stimulus GO:0006974 207 0.011
mitotic cell cycle GO:0000278 195 0.011
regulation of lymphocyte proliferation GO:0050670 117 0.011
extrinsic apoptotic signaling pathway GO:0097191 126 0.011
purine ribonucleoside catabolic process GO:0046130 205 0.011
norepinephrine transport GO:0015874 2 0.011
response to insulin GO:0032868 100 0.011
single organism cell adhesion GO:0098602 156 0.011
positive regulation of t cell activation GO:0050870 101 0.011
t cell proliferation GO:0042098 120 0.011
positive regulation of nervous system development GO:0051962 221 0.011
ribonucleoside triphosphate metabolic process GO:0009199 220 0.011
cellular response to acid chemical GO:0071229 68 0.011
nucleotide catabolic process GO:0009166 217 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
purine nucleoside catabolic process GO:0006152 205 0.011
rho protein signal transduction GO:0007266 32 0.011
leukocyte homeostasis GO:0001776 79 0.011
hematopoietic progenitor cell differentiation GO:0002244 143 0.011
regulation of lymphocyte differentiation GO:0045619 107 0.010
regulation of defense response to fungus GO:1900150 1 0.010
regulation of cell adhesion GO:0030155 154 0.010
myoblast differentiation GO:0045445 52 0.010
purine nucleotide catabolic process GO:0006195 211 0.010
positive regulation of interferon alpha production GO:0032727 4 0.010
protein oligomerization GO:0051259 67 0.010
protein localization to organelle GO:0033365 185 0.010
forebrain development GO:0030900 302 0.010
toll like receptor signaling pathway GO:0002224 38 0.010
protein alkylation GO:0008213 81 0.010
leukocyte proliferation GO:0070661 172 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.010
rna processing GO:0006396 105 0.010
positive regulation of t helper 2 cell cytokine production GO:2000553 3 0.010
cytosolic calcium ion transport GO:0060401 48 0.010
multicellular organism growth GO:0035264 161 0.010
regulation of toll like receptor signaling pathway GO:0034121 20 0.010
exocytosis GO:0006887 121 0.010
macromolecule glycosylation GO:0043413 55 0.010

Isg20 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.046
disease of anatomical entity DOID:7 0 0.046
hematopoietic system disease DOID:74 0 0.032
disease of metabolism DOID:0014667 0 0.027
anemia DOID:2355 0 0.018
nervous system disease DOID:863 0 0.014
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010