Mus musculus

0 known processes

LOC674895

serine/threonine-protein kinase Nek10-like

LOC674895 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular ketone metabolic process GO:0010565 66 0.069
regulation of cellular amino acid metabolic process GO:0006521 5 0.066
amine metabolic process GO:0009308 45 0.060
cellular ketone metabolic process GO:0042180 84 0.057
cellular amine metabolic process GO:0044106 44 0.054
positive regulation of cellular amine metabolic process GO:0033240 5 0.047
regulation of cellular amine metabolic process GO:0033238 20 0.046
regulation of secretion by cell GO:1903530 249 0.041
peptidyl amino acid modification GO:0018193 336 0.040
positive regulation of protein modification process GO:0031401 299 0.040
positive regulation of transferase activity GO:0051347 167 0.039
cellular amino acid metabolic process GO:0006520 103 0.038
ras protein signal transduction GO:0007265 77 0.036
regulation of cellular response to stress GO:0080135 159 0.035
mapk cascade GO:0000165 281 0.034
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.033
regulation of transferase activity GO:0051338 263 0.032
regulation of organelle organization GO:0033043 289 0.029
regulation of cell migration GO:0030334 219 0.029
small gtpase mediated signal transduction GO:0007264 97 0.028
positive regulation of protein phosphorylation GO:0001934 242 0.028
regulation of secretion GO:0051046 274 0.028
detection of chemical stimulus involved in sensory perception of smell GO:0050911 4 0.028
male gamete generation GO:0048232 285 0.027
spermatogenesis GO:0007283 284 0.027
cell adhesion GO:0007155 329 0.027
regulation of cell cycle GO:0051726 281 0.027
regulation of kinase activity GO:0043549 249 0.027
single organism cell adhesion GO:0098602 156 0.026
hematopoietic progenitor cell differentiation GO:0002244 143 0.026
microtubule based process GO:0007017 236 0.026
nucleoside phosphate metabolic process GO:0006753 338 0.026
leukocyte differentiation GO:0002521 342 0.026
regulation of mapk cascade GO:0043408 248 0.025
g protein coupled receptor signaling pathway GO:0007186 243 0.025
regulation of protein kinase activity GO:0045859 232 0.024
positive regulation of mapk cascade GO:0043410 170 0.024
positive regulation of kinase activity GO:0033674 155 0.024
response to organonitrogen compound GO:0010243 246 0.024
positive regulation of organelle organization GO:0010638 128 0.023
oxidation reduction process GO:0055114 342 0.023
lymphocyte differentiation GO:0030098 242 0.023
regulation of cell motility GO:2000145 236 0.023
actin cytoskeleton organization GO:0030036 220 0.023
organelle localization GO:0051640 179 0.023
positive regulation of protein kinase activity GO:0045860 144 0.023
regulation of cellular catabolic process GO:0031329 242 0.023
regulation of protein serine threonine kinase activity GO:0071900 157 0.022
cytokine production GO:0001816 319 0.022
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.022
cellular homeostasis GO:0019725 240 0.022
nucleotide metabolic process GO:0009117 332 0.022
organic cyclic compound catabolic process GO:1901361 295 0.022
macromolecule catabolic process GO:0009057 281 0.022
purine nucleotide metabolic process GO:0006163 302 0.021
negative regulation of cell proliferation GO:0008285 296 0.021
cellular nitrogen compound catabolic process GO:0044270 280 0.021
purine ribonucleotide metabolic process GO:0009150 290 0.021
ribonucleotide metabolic process GO:0009259 291 0.020
heterocycle catabolic process GO:0046700 280 0.020
neuron death GO:0070997 154 0.020
negative regulation of secretion GO:0051048 61 0.020
carbohydrate metabolic process GO:0005975 230 0.020
response to growth factor GO:0070848 198 0.020
organonitrogen compound catabolic process GO:1901565 264 0.020
protein modification by small protein conjugation or removal GO:0070647 207 0.020
cellular response to lipid GO:0071396 145 0.020
response to organic cyclic compound GO:0014070 198 0.020
cation transport GO:0006812 399 0.019
dna metabolic process GO:0006259 303 0.019
cellular chemical homeostasis GO:0055082 215 0.019
vesicle localization GO:0051648 86 0.019
sensory perception GO:0007600 245 0.019
apoptotic signaling pathway GO:0097190 306 0.019
peptidyl serine phosphorylation GO:0018105 74 0.019
intracellular protein transport GO:0006886 204 0.019
protein processing GO:0016485 163 0.019
cytoplasmic transport GO:0016482 234 0.019
transmembrane transport GO:0055085 412 0.019
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.019
peptidyl serine modification GO:0018209 83 0.019
regulation of protein localization GO:0032880 231 0.019
cell type specific apoptotic process GO:0097285 268 0.018
positive regulation of hydrolase activity GO:0051345 148 0.018
cellular response to growth factor stimulus GO:0071363 197 0.018
nitrogen compound transport GO:0071705 271 0.018
nucleobase containing small molecule metabolic process GO:0055086 352 0.018
immune effector process GO:0002252 321 0.018
cellular response to nutrient levels GO:0031669 64 0.018
positive regulation of programmed cell death GO:0043068 218 0.018
photoreceptor cell differentiation GO:0046530 52 0.018
organelle fission GO:0048285 170 0.018
cellular response to organonitrogen compound GO:0071417 145 0.018
purine nucleoside metabolic process GO:0042278 241 0.018
protein localization to organelle GO:0033365 185 0.018
regulation of cell adhesion GO:0030155 154 0.018
neuron apoptotic process GO:0051402 142 0.018
regulation of vesicle mediated transport GO:0060627 139 0.017
ribonucleoside metabolic process GO:0009119 245 0.017
regulation of cytokine production GO:0001817 266 0.017
regulation of actin cytoskeleton organization GO:0032956 84 0.017
regulation of cellular component biogenesis GO:0044087 181 0.017
ribose phosphate metabolic process GO:0019693 291 0.017
learning or memory GO:0007611 148 0.017
multicellular organismal signaling GO:0035637 91 0.017
cellular response to extracellular stimulus GO:0031668 81 0.017
cellular lipid metabolic process GO:0044255 323 0.016
regulation of purine nucleotide metabolic process GO:1900542 169 0.016
purine containing compound metabolic process GO:0072521 311 0.016
protein catabolic process GO:0030163 221 0.016
mitotic cell cycle GO:0000278 195 0.016
response to oxygen levels GO:0070482 62 0.016
purine nucleoside triphosphate metabolic process GO:0009144 226 0.016
nucleoside triphosphate metabolic process GO:0009141 230 0.016
cognition GO:0050890 149 0.016
purine ribonucleoside metabolic process GO:0046128 241 0.016
regulation of hydrolase activity GO:0051336 246 0.016
cation homeostasis GO:0055080 212 0.016
germ cell development GO:0007281 185 0.016
negative regulation of molecular function GO:0044092 258 0.016
regulation of actin filament based process GO:0032970 99 0.016
regulation of map kinase activity GO:0043405 120 0.016
purine ribonucleotide catabolic process GO:0009154 208 0.016
cellular response to external stimulus GO:0071496 88 0.016
positive regulation of cellular component biogenesis GO:0044089 94 0.016
response to acid chemical GO:0001101 111 0.016
t cell differentiation GO:0030217 174 0.016
transmission of nerve impulse GO:0019226 76 0.016
mitochondrion organization GO:0007005 134 0.015
negative regulation of cell cycle GO:0045786 123 0.015
homeostasis of number of cells GO:0048872 210 0.015
regulation of proteolysis GO:0030162 164 0.015
extrinsic apoptotic signaling pathway GO:0097191 126 0.015
regulation of neuron differentiation GO:0045664 281 0.015
protein modification by small protein conjugation GO:0032446 187 0.015
carbohydrate derivative catabolic process GO:1901136 231 0.015
myeloid cell differentiation GO:0030099 233 0.015
maintenance of location GO:0051235 89 0.015
glycosyl compound catabolic process GO:1901658 206 0.015
endomembrane system organization GO:0010256 147 0.015
protein targeting GO:0006605 143 0.015
rho protein signal transduction GO:0007266 32 0.015
mitotic cell cycle process GO:1903047 159 0.015
ion transmembrane transport GO:0034220 361 0.015
regulation of membrane potential GO:0042391 192 0.015
establishment of vesicle localization GO:0051650 81 0.015
aromatic compound catabolic process GO:0019439 286 0.015
protein maturation GO:0051604 176 0.015
nucleoside catabolic process GO:0009164 206 0.014
protein oligomerization GO:0051259 67 0.014
olfactory learning GO:0008355 2 0.014
regulation of anatomical structure size GO:0090066 178 0.014
nucleocytoplasmic transport GO:0006913 139 0.014
regulation of hormone levels GO:0010817 211 0.014
positive regulation of nucleotide metabolic process GO:0045981 114 0.014
inflammatory response GO:0006954 244 0.014
regulation of cell cycle process GO:0010564 160 0.014
regulation of apoptotic signaling pathway GO:2001233 197 0.014
dephosphorylation GO:0016311 129 0.014
regulation of cell activation GO:0050865 289 0.014
nuclear transport GO:0051169 139 0.014
positive regulation of nervous system development GO:0051962 221 0.014
purine containing compound catabolic process GO:0072523 213 0.014
reactive oxygen species metabolic process GO:0072593 84 0.014
carbohydrate homeostasis GO:0033500 128 0.014
exocytosis GO:0006887 121 0.014
negative regulation of cellular protein metabolic process GO:0032269 247 0.014
digestive system development GO:0055123 200 0.014
cell substrate adhesion GO:0031589 130 0.014
action potential GO:0001508 78 0.014
erk1 and erk2 cascade GO:0070371 77 0.014
camera type eye development GO:0043010 266 0.014
regulation of ras protein signal transduction GO:0046578 114 0.014
nucleoside phosphate catabolic process GO:1901292 222 0.014
carbohydrate derivative biosynthetic process GO:1901137 183 0.014
posttranscriptional regulation of gene expression GO:0010608 155 0.014
establishment of organelle localization GO:0051656 122 0.014
negative regulation of protein metabolic process GO:0051248 282 0.014
multicellular organismal homeostasis GO:0048871 164 0.014
regulation of cell projection organization GO:0031344 206 0.013
t cell activation GO:0042110 289 0.013
peptide transport GO:0015833 133 0.013
membrane organization GO:0061024 245 0.013
establishment of protein localization to organelle GO:0072594 118 0.013
ribonucleoside catabolic process GO:0042454 206 0.013
organonitrogen compound biosynthetic process GO:1901566 192 0.013
microtubule based movement GO:0007018 84 0.013
glucose homeostasis GO:0042593 128 0.013
lipid biosynthetic process GO:0008610 179 0.013
regulation of protein transport GO:0051223 163 0.013
stem cell differentiation GO:0048863 268 0.013
response to inorganic substance GO:0010035 96 0.013
cellular protein catabolic process GO:0044257 155 0.013
metal ion homeostasis GO:0055065 189 0.013
organophosphate catabolic process GO:0046434 232 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.013
cellular response to amino acid stimulus GO:0071230 29 0.013
purine nucleoside triphosphate catabolic process GO:0009146 203 0.013
nucleotide catabolic process GO:0009166 217 0.013
alpha beta t cell activation GO:0046631 91 0.013
regulation of neuron death GO:1901214 134 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.013
glycosyl compound metabolic process GO:1901657 246 0.013
nucleoside triphosphate catabolic process GO:0009143 205 0.013
negative regulation of immune system process GO:0002683 209 0.013
positive regulation of cell development GO:0010720 237 0.013
amide transport GO:0042886 138 0.013
protein import into nucleus GO:0006606 95 0.013
regulation of mitotic cell cycle GO:0007346 126 0.013
regulation of neuron apoptotic process GO:0043523 122 0.013
regulation of erk1 and erk2 cascade GO:0070372 71 0.012
response to extracellular stimulus GO:0009991 127 0.012
response to oxidative stress GO:0006979 123 0.012
response to nutrient levels GO:0031667 109 0.012
positive regulation of cytoskeleton organization GO:0051495 49 0.012
positive regulation of cell death GO:0010942 224 0.012
circulatory system process GO:0003013 197 0.012
negative regulation of cellular amine metabolic process GO:0033239 1 0.012
negative regulation of neuron apoptotic process GO:0043524 92 0.012
learning GO:0007612 98 0.012
ribonucleotide catabolic process GO:0009261 208 0.012
sequestering of calcium ion GO:0051208 18 0.012
protein ubiquitination GO:0016567 171 0.012
actin filament organization GO:0007015 113 0.012
inorganic ion transmembrane transport GO:0098660 234 0.012
negative regulation of neuron death GO:1901215 98 0.012
negative regulation of intracellular signal transduction GO:1902532 167 0.012
modification dependent macromolecule catabolic process GO:0043632 133 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.012
cation transmembrane transport GO:0098655 266 0.012
gtp catabolic process GO:0006184 143 0.012
response to amino acid GO:0043200 37 0.012
ribonucleoside triphosphate catabolic process GO:0009203 199 0.012
organophosphate biosynthetic process GO:0090407 122 0.012
cellular macromolecule catabolic process GO:0044265 206 0.012
regulation of homeostatic process GO:0032844 182 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.012
cellular response to acid chemical GO:0071229 68 0.012
cellular response to dna damage stimulus GO:0006974 207 0.012
generation of precursor metabolites and energy GO:0006091 103 0.012
purine nucleoside catabolic process GO:0006152 205 0.012
regulation of cytoskeleton organization GO:0051493 122 0.011
single organism nuclear import GO:1902593 95 0.011
epithelial cell development GO:0002064 159 0.011
cellular response to abiotic stimulus GO:0071214 56 0.011
cellular response to hormone stimulus GO:0032870 150 0.011
nucleoside metabolic process GO:0009116 246 0.011
sequestering of metal ion GO:0051238 19 0.011
regulation of cellular component size GO:0032535 121 0.011
regulation of establishment of protein localization GO:0070201 181 0.011
multi multicellular organism process GO:0044706 109 0.011
response to starvation GO:0042594 65 0.011
regulation of lymphocyte activation GO:0051249 240 0.011
regulation of protein maturation GO:1903317 96 0.011
regionalization GO:0003002 337 0.011
regulation of protein catabolic process GO:0042176 108 0.011
viral gene expression GO:0019080 3 0.011
response to steroid hormone GO:0048545 56 0.011
regulation of nucleotide catabolic process GO:0030811 122 0.011
gonad development GO:0008406 141 0.011
regulation of nucleoside metabolic process GO:0009118 130 0.011
negative regulation of apoptotic signaling pathway GO:2001234 104 0.011
oocyte axis specification GO:0007309 2 0.011
microtubule cytoskeleton organization GO:0000226 157 0.011
response to drug GO:0042493 75 0.011
peptide hormone secretion GO:0030072 109 0.011
negative regulation of cellular catabolic process GO:0031330 47 0.011
regulation of inflammatory response GO:0050727 147 0.011
response to osmotic stress GO:0006970 21 0.011
response to lipopolysaccharide GO:0032496 128 0.011
blood circulation GO:0008015 195 0.011
response to testosterone GO:0033574 3 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
muscle contraction GO:0006936 101 0.011
cellular response to organic cyclic compound GO:0071407 87 0.011
cellular response to starvation GO:0009267 57 0.011
positive regulation of neuron differentiation GO:0045666 141 0.011
cellular response to peptide hormone stimulus GO:0071375 92 0.011
stem cell maintenance GO:0019827 130 0.011
respiratory tube development GO:0030323 167 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.011
cellular response to biotic stimulus GO:0071216 92 0.011
regulation of system process GO:0044057 200 0.011
inorganic cation transmembrane transport GO:0098662 207 0.011
positive regulation of cell adhesion GO:0045785 80 0.011
lung development GO:0030324 164 0.010
insulin secretion GO:0030073 89 0.010
monocarboxylic acid metabolic process GO:0032787 191 0.010
synaptic transmission GO:0007268 329 0.010
negative regulation of phosphate metabolic process GO:0045936 184 0.010
regulation of nucleotide metabolic process GO:0006140 169 0.010
positive regulation of secretion GO:0051047 130 0.010
nuclear division GO:0000280 158 0.010
response to molecule of bacterial origin GO:0002237 143 0.010
negative regulation of cellular component organization GO:0051129 194 0.010
negative regulation of phosphorylation GO:0042326 166 0.010
chemotaxis GO:0006935 247 0.010
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.010
ribonucleoside triphosphate metabolic process GO:0009199 220 0.010
positive regulation of cell motility GO:2000147 116 0.010
anatomical structure homeostasis GO:0060249 145 0.010
regulation of feeding behavior GO:0060259 3 0.010
spermatid development GO:0007286 108 0.010
glycoprotein metabolic process GO:0009100 116 0.010
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.010
regulation of reactive oxygen species metabolic process GO:2000377 40 0.010
sensory organ morphogenesis GO:0090596 242 0.010
spermatid differentiation GO:0048515 115 0.010
divalent inorganic cation transport GO:0072511 178 0.010
epidermis development GO:0008544 187 0.010
hormone secretion GO:0046879 128 0.010
response to peptide GO:1901652 136 0.010
meiotic cell cycle GO:0051321 122 0.010
small molecule biosynthetic process GO:0044283 132 0.010
leukocyte mediated immunity GO:0002443 174 0.010
divalent metal ion transport GO:0070838 172 0.010
regulation of leukocyte differentiation GO:1902105 159 0.010
negative regulation of organelle organization GO:0010639 90 0.010
compound eye development GO:0048749 1 0.010
regulation of t cell activation GO:0050863 170 0.010
purine nucleotide catabolic process GO:0006195 211 0.010

LOC674895 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
muscular disease DOID:0080000 0 0.062
disease of anatomical entity DOID:7 0 0.062
musculoskeletal system disease DOID:17 0 0.062
muscle tissue disease DOID:66 0 0.062
cardiovascular system disease DOID:1287 0 0.033
nervous system disease DOID:863 0 0.021
heart disease DOID:114 0 0.018
central nervous system disease DOID:331 0 0.014
disease of metabolism DOID:0014667 0 0.013
myopathy DOID:423 0 0.011
cardiomyopathy DOID:0050700 0 0.011
intrinsic cardiomyopathy DOID:0060036 0 0.011