Mus musculus

67 known processes

Pcgf6

polycomb group ring finger 6

(Aliases: 4933407A11Rik,AI604840,MGC106622,Rnf134,MBLR)

Pcgf6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of immature t cell proliferation GO:0033091 4 0.897
Mouse
covalent chromatin modification GO:0016569 163 0.728
Mouse
histone h2a ubiquitination GO:0033522 3 0.575
protein modification by small protein conjugation or removal GO:0070647 207 0.469
Mouse
histone h2a monoubiquitination GO:0035518 1 0.464
methylation GO:0032259 134 0.405
Mouse
chromatin modification GO:0016568 187 0.393
Mouse
dna methylation GO:0006306 43 0.393
Mouse
dna metabolic process GO:0006259 303 0.376
Mouse
histone modification GO:0016570 159 0.314
Mouse
gene silencing GO:0016458 38 0.304
regionalization GO:0003002 337 0.297
Mouse
histone methylation GO:0016571 71 0.279
protein modification by small protein conjugation GO:0032446 187 0.239
Mouse
trunk segmentation GO:0035290 4 0.215
histone monoubiquitination GO:0010390 3 0.212
apoptotic signaling pathway GO:0097190 306 0.155
Mouse
protein ubiquitination GO:0016567 171 0.153
Mouse
protein methylation GO:0006479 81 0.113
mitotic cell cycle GO:0000278 195 0.110
neural tube development GO:0021915 160 0.104
Mouse
cell cycle comprising mitosis without cytokinesis GO:0033301 1 0.092
germ cell development GO:0007281 185 0.092
internal protein amino acid acetylation GO:0006475 42 0.088
Mouse
protein alkylation GO:0008213 81 0.087
chromatin organization GO:0006325 206 0.086
Mouse
skeletal system development GO:0001501 356 0.085
Mouse
dna modification GO:0006304 50 0.080
Mouse
response to radiation GO:0009314 165 0.078
developmental maturation GO:0021700 193 0.077
peptidyl amino acid modification GO:0018193 336 0.075
Mouse
regulation of cell cycle GO:0051726 281 0.071
regulation of apoptotic signaling pathway GO:2001233 197 0.070
Mouse
peptidyl lysine modification GO:0018205 77 0.070
Mouse
regulation of histone h3 k36 methylation GO:0000414 1 0.069
positive regulation of cell activation GO:0050867 158 0.066
Mouse
cellular response to dna damage stimulus GO:0006974 207 0.064
mrna splicing via spliceosome GO:0000398 43 0.061
camera type eye development GO:0043010 266 0.060
regulation of lymphocyte activation GO:0051249 240 0.059
Mouse
regulation of cellular component biogenesis GO:0044087 181 0.059
macromolecule methylation GO:0043414 120 0.059
Mouse
response to ionizing radiation GO:0010212 42 0.059
dna alkylation GO:0006305 43 0.058
Mouse
regulation of protein complex assembly GO:0043254 83 0.057
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.053
histone ubiquitination GO:0016574 10 0.052
Mouse
organelle assembly GO:0070925 177 0.051
ribose phosphate metabolic process GO:0019693 291 0.050
negative regulation of apoptotic signaling pathway GO:2001234 104 0.050
Mouse
cellular ketone metabolic process GO:0042180 84 0.048
signal transduction by p53 class mediator GO:0072331 51 0.047
lymphocyte differentiation GO:0030098 242 0.045
Mouse
immature t cell proliferation GO:0033079 8 0.045
Mouse
ubiquitin dependent protein catabolic process GO:0006511 129 0.045
regulation of cell activation GO:0050865 289 0.044
Mouse
cell maturation GO:0048469 127 0.043
cellular protein complex assembly GO:0043623 116 0.042
positive regulation of b cell activation GO:0050871 49 0.041
Mouse
histone h3 k9 methylation GO:0051567 17 0.040
t cell differentiation GO:0030217 174 0.040
Mouse
rna processing GO:0006396 105 0.039
histone acetylation GO:0016573 41 0.038
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.038
regulation of organelle organization GO:0033043 289 0.038
proteasomal protein catabolic process GO:0010498 98 0.038
intrinsic apoptotic signaling pathway GO:0097193 132 0.037
negative regulation of gene expression epigenetic GO:0045814 15 0.037
histone h3 k36 methylation GO:0010452 6 0.037
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.037
cellular macromolecule catabolic process GO:0044265 206 0.036
positive regulation of apoptotic process GO:0043065 217 0.036
female gamete generation GO:0007292 74 0.035
intracellular receptor signaling pathway GO:0030522 74 0.035
regulation of cell cycle process GO:0010564 160 0.034
nucleobase containing small molecule metabolic process GO:0055086 352 0.034
protein acylation GO:0043543 64 0.033
Mouse
ribonucleotide metabolic process GO:0009259 291 0.033
organic cyclic compound catabolic process GO:1901361 295 0.033
segmentation GO:0035282 93 0.032
cellular protein catabolic process GO:0044257 155 0.031
tube closure GO:0060606 91 0.031
negative regulation of cellular component organization GO:0051129 194 0.031
regulation of protein stability GO:0031647 52 0.031
dendrite development GO:0016358 115 0.030
positive regulation of organelle organization GO:0010638 128 0.030
negative regulation of mitotic cell cycle GO:0045930 58 0.029
regulation of leukocyte differentiation GO:1902105 159 0.029
Mouse
spermatogenesis GO:0007283 284 0.029
macromolecule catabolic process GO:0009057 281 0.028
skeletal system morphogenesis GO:0048705 203 0.028
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.028
posttranscriptional regulation of gene expression GO:0010608 155 0.027
mitotic cell cycle process GO:1903047 159 0.027
heterocycle catabolic process GO:0046700 280 0.027
meiotic cell cycle GO:0051321 122 0.027
membrane organization GO:0061024 245 0.027
regulation of mitotic cell cycle GO:0007346 126 0.026
retina development in camera type eye GO:0060041 119 0.026
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.026
cellular amino acid metabolic process GO:0006520 103 0.026
cell type specific apoptotic process GO:0097285 268 0.026
modification dependent protein catabolic process GO:0019941 133 0.026
organelle fission GO:0048285 170 0.026
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 34 0.025
leukocyte differentiation GO:0002521 342 0.025
Mouse
purine containing compound metabolic process GO:0072521 311 0.025
nuclear division GO:0000280 158 0.025
cellular nitrogen compound catabolic process GO:0044270 280 0.025
purine ribonucleotide metabolic process GO:0009150 290 0.024
nucleotide metabolic process GO:0009117 332 0.024
negative regulation of dna replication GO:0008156 4 0.024
negative regulation of organelle organization GO:0010639 90 0.023
transcription from rna polymerase iii promoter GO:0006383 3 0.023
rostrocaudal neural tube patterning GO:0021903 12 0.023
Mouse
positive regulation of lymphocyte differentiation GO:0045621 61 0.022
Mouse
response to acid chemical GO:0001101 111 0.022
cajal body organization GO:0030576 1 0.022
protein complex disassembly GO:0043241 40 0.022
erythrocyte differentiation GO:0030218 88 0.022
positive regulation of cellular component biogenesis GO:0044089 94 0.022
cell division GO:0051301 120 0.022
Mouse
homeostasis of number of cells GO:0048872 210 0.022
modification dependent macromolecule catabolic process GO:0043632 133 0.022
oocyte construction GO:0007308 2 0.021
nucleotide catabolic process GO:0009166 217 0.021
purine nucleoside catabolic process GO:0006152 205 0.021
ribonucleoside triphosphate metabolic process GO:0009199 220 0.021
nucleoside phosphate metabolic process GO:0006753 338 0.021
nucleoside triphosphate metabolic process GO:0009141 230 0.021
positive regulation of t cell activation GO:0050870 101 0.021
Mouse
small gtpase mediated signal transduction GO:0007264 97 0.021
glycosyl compound catabolic process GO:1901658 206 0.021
chromosome organization involved in meiosis GO:0070192 39 0.020
protein targeting GO:0006605 143 0.020
regulation of cellular amine metabolic process GO:0033238 20 0.020
negative regulation of molecular function GO:0044092 258 0.020
oocyte axis specification GO:0007309 2 0.020
glycosyl compound metabolic process GO:1901657 246 0.019
embryonic epithelial tube formation GO:0001838 130 0.019
chromatin silencing GO:0006342 15 0.019
regulation of cell division GO:0051302 76 0.019
digestive tract development GO:0048565 190 0.019
ribonucleoside catabolic process GO:0042454 206 0.019
nucleoside catabolic process GO:0009164 206 0.019
positive regulation of t cell differentiation in thymus GO:0033089 13 0.019
Mouse
gland development GO:0048732 330 0.019
purine nucleoside triphosphate metabolic process GO:0009144 226 0.019
positive regulation of t cell proliferation GO:0042102 52 0.019
Mouse
cellular amine metabolic process GO:0044106 44 0.019
regulation of mrna metabolic process GO:1903311 43 0.018
negative regulation of cell cycle GO:0045786 123 0.018
axon guidance GO:0007411 141 0.018
gastrulation GO:0007369 116 0.018
histone lysine methylation GO:0034968 50 0.018
positive regulation of cellular amine metabolic process GO:0033240 5 0.018
ribonucleoside triphosphate catabolic process GO:0009203 199 0.018
regulation of t cell proliferation GO:0042129 92 0.017
Mouse
mitotic cell cycle embryonic GO:0045448 5 0.017
cellular component assembly involved in morphogenesis GO:0010927 139 0.017
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.017
respiratory tube development GO:0030323 167 0.016
intracellular mrna localization GO:0008298 4 0.016
nucleoside triphosphate catabolic process GO:0009143 205 0.016
positive regulation of cell death GO:0010942 224 0.016
regulation of cellular ketone metabolic process GO:0010565 66 0.016
actin cytoskeleton organization GO:0030036 220 0.016
purine containing compound catabolic process GO:0072523 213 0.016
microtubule based process GO:0007017 236 0.016
negative regulation of immune system process GO:0002683 209 0.016
regulation of t cell activation GO:0050863 170 0.016
Mouse
purine ribonucleotide catabolic process GO:0009154 208 0.016
cell fate commitment GO:0045165 210 0.016
aromatic compound catabolic process GO:0019439 286 0.016
production of molecular mediator of immune response GO:0002440 103 0.016
regulation of b cell activation GO:0050864 81 0.016
Mouse
amine metabolic process GO:0009308 45 0.015
embryonic skeletal system morphogenesis GO:0048704 91 0.015
Mouse
myeloid cell differentiation GO:0030099 233 0.015
neural tube patterning GO:0021532 43 0.015
Mouse
mrna metabolic process GO:0016071 84 0.015
carbohydrate derivative catabolic process GO:1901136 231 0.015
negative regulation of intracellular signal transduction GO:1902532 167 0.015
organonitrogen compound catabolic process GO:1901565 264 0.015
purine nucleotide metabolic process GO:0006163 302 0.015
regulation of smoothened signaling pathway GO:0008589 58 0.015
mitotic chromosome condensation GO:0007076 1 0.015
cellular response to acid chemical GO:0071229 68 0.015
cell cycle checkpoint GO:0000075 47 0.015
embryonic organ morphogenesis GO:0048562 276 0.015
Mouse
cellular homeostasis GO:0019725 240 0.014
cellular response to sterol GO:0036315 2 0.014
endodermal cell fate specification GO:0001714 4 0.014
sensory perception GO:0007600 245 0.014
negative regulation of cell cycle process GO:0010948 69 0.014
mrna processing GO:0006397 63 0.014
negative regulation of cell cycle phase transition GO:1901988 48 0.014
positive regulation of programmed cell death GO:0043068 218 0.014
cytoplasmic transport GO:0016482 234 0.014
transdifferentiation GO:0060290 1 0.014
engulfment of apoptotic cell GO:0043652 3 0.014
rna polyadenylation GO:0043631 6 0.014
response to organic cyclic compound GO:0014070 198 0.014
positive regulation of growth GO:0045927 104 0.014
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.014
protein monoubiquitination GO:0006513 11 0.014
regulation of cell migration GO:0030334 219 0.014
positive regulation of protein complex assembly GO:0031334 45 0.014
dna templated transcription termination GO:0006353 4 0.014
response to hydrogen peroxide GO:0042542 32 0.014
Mouse
immune effector process GO:0002252 321 0.014
t cell activation GO:0042110 289 0.013
Mouse
regulation of protein processing GO:0070613 96 0.013
histone deubiquitination GO:0016578 2 0.013
wound healing GO:0042060 157 0.013
cellular response to lipid GO:0071396 145 0.013
b cell proliferation GO:0042100 53 0.013
Mouse
response to reactive oxygen species GO:0000302 56 0.013
Mouse
intracellular protein transport GO:0006886 204 0.013
oxidation reduction process GO:0055114 342 0.013
purine ribonucleoside metabolic process GO:0046128 241 0.013
cilium morphogenesis GO:0060271 102 0.013
heterochromatin organization GO:0070828 4 0.013
nucleus organization GO:0006997 45 0.013
purine nucleoside triphosphate catabolic process GO:0009146 203 0.012
b cell activation GO:0042113 161 0.012
Mouse
stem cell development GO:0048864 219 0.012
gtp metabolic process GO:0046039 144 0.012
dna repair GO:0006281 107 0.012
nucleocytoplasmic transport GO:0006913 139 0.012
oogenesis GO:0048477 56 0.012
carbohydrate derivative biosynthetic process GO:1901137 183 0.012
protein processing GO:0016485 163 0.012
t cell proliferation GO:0042098 120 0.012
Mouse
digestive system development GO:0055123 200 0.012
spinal cord development GO:0021510 81 0.012
peptidyl lysine methylation GO:0018022 29 0.012
response to gamma radiation GO:0010332 22 0.012
regulation of anatomical structure size GO:0090066 178 0.012
regulation of mitotic cell cycle phase transition GO:1901990 73 0.012
smoothened signaling pathway GO:0007224 105 0.012
negative regulation of cell proliferation GO:0008285 296 0.012
nucleoside phosphate catabolic process GO:1901292 222 0.012
negative regulation of nervous system development GO:0051961 156 0.012
ribonucleoside metabolic process GO:0009119 245 0.012
dna recombination GO:0006310 92 0.012
locomotory behavior GO:0007626 195 0.012
regulation of neural precursor cell proliferation GO:2000177 70 0.011
chronological cell aging GO:0001300 1 0.011
protein catabolic process GO:0030163 221 0.011
cell adhesion GO:0007155 329 0.011
cell cycle g1 s phase transition GO:0044843 57 0.011
positive regulation of cell development GO:0010720 237 0.011
regulation of cellular response to stress GO:0080135 159 0.011
protein maturation GO:0051604 176 0.011
regulation of intracellular protein transport GO:0033157 82 0.011
purine nucleoside metabolic process GO:0042278 241 0.011
rna 3 end processing GO:0031123 20 0.011
transmembrane transport GO:0055085 412 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.011
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.011
ras protein signal transduction GO:0007265 77 0.011
regulation of epithelial cell proliferation GO:0050678 141 0.011
protein autophosphorylation GO:0046777 61 0.011
meiotic nuclear division GO:0007126 115 0.011
protein localization to organelle GO:0033365 185 0.011
regulation of nucleoside metabolic process GO:0009118 130 0.011
regulation of binding GO:0051098 111 0.011
angiogenesis GO:0001525 201 0.011
regulation of mrna splicing via spliceosome GO:0048024 32 0.011
cytokine production GO:0001816 319 0.011
stem cell division GO:0017145 30 0.011
Mouse
organonitrogen compound biosynthetic process GO:1901566 192 0.011
cilium assembly GO:0042384 81 0.011
regulation of protein localization GO:0032880 231 0.011
nuclear transport GO:0051169 139 0.011
regulation of embryonic development GO:0045995 71 0.011
negative regulation of cellular protein metabolic process GO:0032269 247 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.011
cellular lipid metabolic process GO:0044255 323 0.011
maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000463 1 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.011
negative regulation of t helper 2 cell differentiation GO:0045629 4 0.010
regulation of carbohydrate metabolic process GO:0006109 75 0.010
neuron death GO:0070997 154 0.010
multicellular organism growth GO:0035264 161 0.010
ribonucleotide catabolic process GO:0009261 208 0.010
regulation of defense response GO:0031347 233 0.010
protein polymerization GO:0051258 57 0.010
negative regulation of protein maturation GO:1903318 79 0.010
ossification GO:0001503 216 0.010
negative regulation of cell development GO:0010721 169 0.010
regulation of production of molecular mediator of immune response GO:0002700 65 0.010
wnt signaling pathway GO:0016055 188 0.010
developmental growth involved in morphogenesis GO:0060560 138 0.010
cellular response to peptide hormone stimulus GO:0071375 92 0.010

Pcgf6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.031
disease of anatomical entity DOID:7 0 0.028
nervous system disease DOID:863 0 0.028
cancer DOID:162 0 0.022
organ system cancer DOID:0050686 0 0.022
central nervous system disease DOID:331 0 0.017
sensory system disease DOID:0050155 0 0.014
eye and adnexa disease DOID:1492 0 0.014
eye disease DOID:5614 0 0.014
endocrine gland cancer DOID:170 0 0.013