Mus musculus

0 known processes

Sfi1

Sfi1 homolog, spindle assembly associated (yeast)

(Aliases: mKIAA0542,RP23-191E3.10,2310047I15Rik)

Sfi1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of nlrp3 inflammasome complex assembly GO:1900226 2 0.092
regulation of reactive oxygen species metabolic process GO:2000377 40 0.061
cellular amine metabolic process GO:0044106 44 0.057
dna metabolic process GO:0006259 303 0.048
small gtpase mediated signal transduction GO:0007264 97 0.045
amine metabolic process GO:0009308 45 0.040
organonitrogen compound catabolic process GO:1901565 264 0.040
nucleotide metabolic process GO:0009117 332 0.040
organic cyclic compound catabolic process GO:1901361 295 0.040
cellular amino acid metabolic process GO:0006520 103 0.039
regulation of nlrp3 inflammasome complex assembly GO:1900225 4 0.037
reactive oxygen species metabolic process GO:0072593 84 0.037
cellular macromolecule catabolic process GO:0044265 206 0.037
protein modification by small protein conjugation or removal GO:0070647 207 0.036
ribonucleotide catabolic process GO:0009261 208 0.035
nucleotide catabolic process GO:0009166 217 0.035
regulation of cellular ketone metabolic process GO:0010565 66 0.034
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.034
positive regulation of actin nucleation GO:0051127 3 0.033
regulation of cellular amine metabolic process GO:0033238 20 0.032
nucleoside triphosphate metabolic process GO:0009141 230 0.032
macromolecule catabolic process GO:0009057 281 0.032
protein modification by small protein conjugation GO:0032446 187 0.032
protein ubiquitination GO:0016567 171 0.032
nucleobase containing small molecule metabolic process GO:0055086 352 0.031
regulation of cellular amino acid metabolic process GO:0006521 5 0.031
glycosyl compound metabolic process GO:1901657 246 0.031
cellular ketone metabolic process GO:0042180 84 0.030
protein catabolic process GO:0030163 221 0.030
actin cytoskeleton organization GO:0030036 220 0.030
ribose phosphate metabolic process GO:0019693 291 0.030
cation transport GO:0006812 399 0.030
regulation of hydrolase activity GO:0051336 246 0.030
purine containing compound metabolic process GO:0072521 311 0.029
heterocycle catabolic process GO:0046700 280 0.029
cytokine production GO:0001816 319 0.029
regulation of cellular catabolic process GO:0031329 242 0.029
purine ribonucleoside metabolic process GO:0046128 241 0.029
purine nucleotide metabolic process GO:0006163 302 0.029
regulation of nucleoside metabolic process GO:0009118 130 0.028
regulation of cytokine production GO:0001817 266 0.028
ribonucleotide metabolic process GO:0009259 291 0.028
nucleoside phosphate catabolic process GO:1901292 222 0.028
ras protein signal transduction GO:0007265 77 0.028
regulation of organelle organization GO:0033043 289 0.027
positive regulation of cellular amine metabolic process GO:0033240 5 0.026
regulation of cellular component biogenesis GO:0044087 181 0.026
dna repair GO:0006281 107 0.026
cellular lipid metabolic process GO:0044255 323 0.026
nucleoside phosphate metabolic process GO:0006753 338 0.026
aromatic compound catabolic process GO:0019439 286 0.026
modification dependent macromolecule catabolic process GO:0043632 133 0.025
purine containing compound catabolic process GO:0072523 213 0.025
purine ribonucleotide metabolic process GO:0009150 290 0.025
ribonucleoside metabolic process GO:0009119 245 0.025
cellular nitrogen compound catabolic process GO:0044270 280 0.025
regulation of protein catabolic process GO:0042176 108 0.025
organophosphate catabolic process GO:0046434 232 0.024
purine nucleotide catabolic process GO:0006195 211 0.024
ribonucleoside triphosphate catabolic process GO:0009203 199 0.024
positive regulation of viral entry into host cell GO:0046598 3 0.024
transmembrane transport GO:0055085 412 0.024
purine nucleoside catabolic process GO:0006152 205 0.023
nucleoside catabolic process GO:0009164 206 0.023
sequestering of metal ion GO:0051238 19 0.023
purine ribonucleotide catabolic process GO:0009154 208 0.023
response to organonitrogen compound GO:0010243 246 0.022
regulation of membrane potential GO:0042391 192 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.022
ion transmembrane transport GO:0034220 361 0.022
ribonucleoside triphosphate metabolic process GO:0009199 220 0.022
positive regulation of ras gtpase activity GO:0032320 65 0.021
viral gene expression GO:0019080 3 0.021
cellular response to dna damage stimulus GO:0006974 207 0.021
regulation of purine nucleotide metabolic process GO:1900542 169 0.021
glycosyl compound catabolic process GO:1901658 206 0.020
maintenance of location GO:0051235 89 0.020
purine nucleoside metabolic process GO:0042278 241 0.020
positive regulation of hydrolase activity GO:0051345 148 0.020
regulation of transferase activity GO:0051338 263 0.020
alcohol metabolic process GO:0006066 116 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.020
carbohydrate derivative catabolic process GO:1901136 231 0.020
cell type specific apoptotic process GO:0097285 268 0.019
positive regulation of protein modification process GO:0031401 299 0.019
apoptotic signaling pathway GO:0097190 306 0.019
purine ribonucleoside catabolic process GO:0046130 205 0.019
response to radiation GO:0009314 165 0.019
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.019
modification dependent protein catabolic process GO:0019941 133 0.019
negative regulation of protein metabolic process GO:0051248 282 0.019
purine nucleoside triphosphate metabolic process GO:0009144 226 0.018
gtp catabolic process GO:0006184 143 0.018
positive regulation of protein phosphorylation GO:0001934 242 0.018
nucleoside metabolic process GO:0009116 246 0.018
negative regulation of cellular component organization GO:0051129 194 0.018
sequestering of calcium ion GO:0051208 18 0.018
negative regulation of cellular protein metabolic process GO:0032269 247 0.018
regulation of protein localization GO:0032880 231 0.018
rho protein signal transduction GO:0007266 32 0.018
multicellular organismal homeostasis GO:0048871 164 0.018
regulation of actin nucleation GO:0051125 4 0.018
monocarboxylic acid metabolic process GO:0032787 191 0.017
nucleoside triphosphate catabolic process GO:0009143 205 0.017
muscle cell differentiation GO:0042692 261 0.017
homeostasis of number of cells GO:0048872 210 0.017
small molecule biosynthetic process GO:0044283 132 0.017
regulation of nucleotide metabolic process GO:0006140 169 0.017
guanosine containing compound catabolic process GO:1901069 144 0.017
regulation of nucleotide catabolic process GO:0030811 122 0.017
wnt signaling pathway GO:0016055 188 0.017
actin filament organization GO:0007015 113 0.017
regulation of purine nucleotide catabolic process GO:0033121 122 0.017
ribonucleoside catabolic process GO:0042454 206 0.016
guanosine containing compound metabolic process GO:1901068 144 0.016
regulation of protein kinase activity GO:0045859 232 0.016
regulation of cell cycle GO:0051726 281 0.016
cellular homeostasis GO:0019725 240 0.016
muscle tissue development GO:0060537 308 0.016
purine nucleoside triphosphate catabolic process GO:0009146 203 0.016
regulation of cell activation GO:0050865 289 0.016
immune response activating signal transduction GO:0002757 116 0.016
protein localization to organelle GO:0033365 185 0.016
regulation of ral gtpase activity GO:0032315 4 0.016
inorganic cation transmembrane transport GO:0098662 207 0.016
cellular protein catabolic process GO:0044257 155 0.016
regulation of protein complex assembly GO:0043254 83 0.016
regulation of cytoskeleton organization GO:0051493 122 0.016
leukocyte differentiation GO:0002521 342 0.016
carbohydrate derivative biosynthetic process GO:1901137 183 0.016
regulation of defense response GO:0031347 233 0.015
organelle fission GO:0048285 170 0.015
regulation of ras protein signal transduction GO:0046578 114 0.015
positive regulation of nucleotide metabolic process GO:0045981 114 0.015
posttranscriptional regulation of gene expression GO:0010608 155 0.015
regulation of secretion GO:0051046 274 0.015
membrane organization GO:0061024 245 0.015
response to organic cyclic compound GO:0014070 198 0.015
nitrogen compound transport GO:0071705 271 0.015
positive regulation of nucleoside metabolic process GO:0045979 91 0.015
sensory perception GO:0007600 245 0.015
positive regulation of gtp catabolic process GO:0033126 85 0.015
organic hydroxy compound metabolic process GO:1901615 203 0.015
positive regulation of kinase activity GO:0033674 155 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.015
positive regulation of cellular catabolic process GO:0031331 148 0.015
positive regulation of nucleotide catabolic process GO:0030813 88 0.015
negative regulation of viral transcription GO:0032897 3 0.015
activation of immune response GO:0002253 138 0.015
urogenital system development GO:0001655 261 0.015
peptidyl amino acid modification GO:0018193 336 0.015
regulation of kinase activity GO:0043549 249 0.015
negative regulation of immune system process GO:0002683 209 0.014
immune response regulating signaling pathway GO:0002764 125 0.014
innate immune response GO:0045087 157 0.014
myeloid cell differentiation GO:0030099 233 0.014
positive regulation of gtpase activity GO:0043547 85 0.014
canonical wnt signaling pathway GO:0060070 130 0.014
covalent chromatin modification GO:0016569 163 0.014
positive regulation of cellular component biogenesis GO:0044089 94 0.014
positive regulation of protein catabolic process GO:0045732 60 0.014
anatomical structure homeostasis GO:0060249 145 0.014
positive regulation of organelle organization GO:0010638 128 0.014
organonitrogen compound biosynthetic process GO:1901566 192 0.014
chromatin organization GO:0006325 206 0.014
positive regulation of cell death GO:0010942 224 0.014
nuclear division GO:0000280 158 0.014
regulation of apoptotic signaling pathway GO:2001233 197 0.014
glycerolipid metabolic process GO:0046486 122 0.014
gtp metabolic process GO:0046039 144 0.014
regulation of actin filament based process GO:0032970 99 0.014
negative regulation of cell development GO:0010721 169 0.014
regulation of actin cytoskeleton organization GO:0032956 84 0.014
anion transport GO:0006820 177 0.013
actin filament polymerization GO:0030041 44 0.013
positive regulation of viral genome replication GO:0045070 2 0.013
negative regulation of multi organism process GO:0043901 68 0.013
striated muscle tissue development GO:0014706 293 0.013
positive regulation of programmed cell death GO:0043068 218 0.013
carboxylic acid biosynthetic process GO:0046394 86 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.013
negative regulation of cell proliferation GO:0008285 296 0.013
compound eye development GO:0048749 1 0.013
positive regulation of transferase activity GO:0051347 167 0.013
cellular protein complex assembly GO:0043623 116 0.013
divalent metal ion transport GO:0070838 172 0.013
negative regulation of molecular function GO:0044092 258 0.013
cellular divalent inorganic cation homeostasis GO:0072503 127 0.013
histone modification GO:0016570 159 0.013
mitotic cell cycle GO:0000278 195 0.013
entry into host GO:0044409 15 0.013
phospholipid metabolic process GO:0006644 87 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.013
cellular response to organonitrogen compound GO:0071417 145 0.013
synaptic transmission GO:0007268 329 0.013
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.013
regulation of ras gtpase activity GO:0032318 88 0.013
cellular ion homeostasis GO:0006873 165 0.013
oxidation reduction process GO:0055114 342 0.012
multicellular organismal signaling GO:0035637 91 0.012
chromatin modification GO:0016568 187 0.012
glucose homeostasis GO:0042593 128 0.012
regulation of protein transport GO:0051223 163 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.012
cell adhesion GO:0007155 329 0.012
renal system development GO:0072001 225 0.012
regulation of secretion by cell GO:1903530 249 0.012
cellular response to lipid GO:0071396 145 0.012
organelle assembly GO:0070925 177 0.012
regulation of interleukin 6 production GO:0032675 55 0.012
extracellular structure organization GO:0043062 148 0.012
regionalization GO:0003002 337 0.012
neuron death GO:0070997 154 0.012
organic hydroxy compound transport GO:0015850 93 0.012
regulation of cell migration GO:0030334 219 0.012
regulation of gtp catabolic process GO:0033124 113 0.012
embryonic organ morphogenesis GO:0048562 276 0.012
regulation of proteolysis GO:0030162 164 0.012
blood vessel morphogenesis GO:0048514 285 0.012
fertilization GO:0009566 127 0.012
regulation of ion transport GO:0043269 215 0.012
response to light stimulus GO:0009416 135 0.012
cellular response to biotic stimulus GO:0071216 92 0.012
calcium ion transport GO:0006816 159 0.012
cation transmembrane transport GO:0098655 266 0.012
transmission of nerve impulse GO:0019226 76 0.012
lipid biosynthetic process GO:0008610 179 0.012
negative regulation of nervous system development GO:0051961 156 0.012
myeloid cell homeostasis GO:0002262 114 0.011
protein polymerization GO:0051258 57 0.011
response to acid chemical GO:0001101 111 0.011
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.011
fatty acid metabolic process GO:0006631 121 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
positive regulation of nervous system development GO:0051962 221 0.011
skeletal system development GO:0001501 356 0.011
regulation of mapk cascade GO:0043408 248 0.011
cytoplasmic transport GO:0016482 234 0.011
regulation of wnt signaling pathway GO:0030111 123 0.011
proteasomal protein catabolic process GO:0010498 98 0.011
methylation GO:0032259 134 0.011
positive regulation of apoptotic process GO:0043065 217 0.011
detection of chemical stimulus involved in sensory perception of taste GO:0050912 3 0.011
protein maturation GO:0051604 176 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.011
steroid metabolic process GO:0008202 119 0.011
organophosphate biosynthetic process GO:0090407 122 0.011
g protein coupled receptor signaling pathway GO:0007186 243 0.011
microtubule based process GO:0007017 236 0.011
regulation of anatomical structure size GO:0090066 178 0.011
cellular response to growth factor stimulus GO:0071363 197 0.011
protein targeting GO:0006605 143 0.011
forebrain development GO:0030900 302 0.011
cellular chemical homeostasis GO:0055082 215 0.011
regulation of neuron differentiation GO:0045664 281 0.011
organic acid biosynthetic process GO:0016053 86 0.011
organic anion transport GO:0015711 137 0.011
actin polymerization or depolymerization GO:0008154 54 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.010
viral transcription GO:0019083 3 0.010
protein localization to nucleus GO:0034504 121 0.010
regulation of lymphocyte activation GO:0051249 240 0.010
cellular response to cytokine stimulus GO:0071345 189 0.010
organic acid transport GO:0015849 101 0.010
protein processing GO:0016485 163 0.010
inorganic ion transmembrane transport GO:0098660 234 0.010
negative regulation of cellular amine metabolic process GO:0033239 1 0.010
neuronal action potential GO:0019228 54 0.010
immune effector process GO:0002252 321 0.010
myosin filament assembly GO:0031034 2 0.010
ubiquitin dependent protein catabolic process GO:0006511 129 0.010
regulation of cell adhesion GO:0030155 154 0.010
establishment or maintenance of cell polarity GO:0007163 86 0.010
embryonic epithelial tube formation GO:0001838 130 0.010
kidney development GO:0001822 213 0.010
mitochondrion organization GO:0007005 134 0.010
retrograde transport endosome to golgi GO:0042147 2 0.010
protein alkylation GO:0008213 81 0.010
divalent inorganic cation transport GO:0072511 178 0.010

Sfi1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
nervous system disease DOID:863 0 0.029
immune system disease DOID:2914 0 0.024
disease of metabolism DOID:0014667 0 0.018
inherited metabolic disorder DOID:655 0 0.017
central nervous system disease DOID:331 0 0.012
hematopoietic system disease DOID:74 0 0.011
musculoskeletal system disease DOID:17 0 0.010