Mus musculus

0 known processes

Plekho2

pleckstrin homology domain containing, family O member 2

(Aliases: MGC30448,Plekhq1,AI840980)

Plekho2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ras protein signal transduction GO:0007265 77 0.716
carbohydrate derivative catabolic process GO:1901136 231 0.707
small gtpase mediated signal transduction GO:0007264 97 0.670
organic cyclic compound catabolic process GO:1901361 295 0.468
positive regulation of gtp catabolic process GO:0033126 85 0.460
purine nucleotide catabolic process GO:0006195 211 0.451
guanosine containing compound metabolic process GO:1901068 144 0.431
purine nucleotide metabolic process GO:0006163 302 0.426
regulation of cellular amine metabolic process GO:0033238 20 0.373
regulation of nucleotide catabolic process GO:0030811 122 0.368
nucleobase containing small molecule metabolic process GO:0055086 352 0.361
positive regulation of protein modification process GO:0031401 299 0.356
heterocycle catabolic process GO:0046700 280 0.343
toll like receptor signaling pathway GO:0002224 38 0.334
nucleoside phosphate metabolic process GO:0006753 338 0.332
cellular amine metabolic process GO:0044106 44 0.331
nucleotide metabolic process GO:0009117 332 0.325
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.310
organelle localization GO:0051640 179 0.301
leukocyte mediated immunity GO:0002443 174 0.301
nucleoside triphosphate catabolic process GO:0009143 205 0.288
ribonucleoside metabolic process GO:0009119 245 0.281
ribonucleoside triphosphate catabolic process GO:0009203 199 0.279
nucleoside triphosphate metabolic process GO:0009141 230 0.275
guanosine containing compound catabolic process GO:1901069 144 0.273
cellular amino acid metabolic process GO:0006520 103 0.266
aromatic compound catabolic process GO:0019439 286 0.265
glycosyl compound catabolic process GO:1901658 206 0.258
nucleoside metabolic process GO:0009116 246 0.251
forebrain development GO:0030900 302 0.250
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.249
cell adhesion GO:0007155 329 0.246
cellular nitrogen compound catabolic process GO:0044270 280 0.243
ribonucleoside catabolic process GO:0042454 206 0.237
nucleoside phosphate catabolic process GO:1901292 222 0.226
nucleotide catabolic process GO:0009166 217 0.220
cell substrate adhesion GO:0031589 130 0.216
purine nucleoside catabolic process GO:0006152 205 0.213
regulation of ras protein signal transduction GO:0046578 114 0.211
gtp metabolic process GO:0046039 144 0.209
ribonucleoside triphosphate metabolic process GO:0009199 220 0.206
purine containing compound metabolic process GO:0072521 311 0.205
cellular ketone metabolic process GO:0042180 84 0.201
purine nucleoside metabolic process GO:0042278 241 0.197
regulation of cellular amino acid metabolic process GO:0006521 5 0.196
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.196
positive regulation of cellular catabolic process GO:0031331 148 0.190
purine ribonucleoside catabolic process GO:0046130 205 0.189
purine ribonucleotide metabolic process GO:0009150 290 0.187
nucleoside catabolic process GO:0009164 206 0.187
muscle cell differentiation GO:0042692 261 0.182
ribonucleotide catabolic process GO:0009261 208 0.182
lymphocyte differentiation GO:0030098 242 0.180
regulation of nucleoside metabolic process GO:0009118 130 0.178
t cell activation GO:0042110 289 0.176
purine nucleoside triphosphate metabolic process GO:0009144 226 0.171
ribose phosphate metabolic process GO:0019693 291 0.156
regulation of vesicle mediated transport GO:0060627 139 0.148
glycosyl compound metabolic process GO:1901657 246 0.144
purine ribonucleoside metabolic process GO:0046128 241 0.144
regulation of purine nucleotide catabolic process GO:0033121 122 0.143
negative regulation of phosphorylation GO:0042326 166 0.139
regulation of t cell differentiation GO:0045580 83 0.138
gtp catabolic process GO:0006184 143 0.138
axon guidance GO:0007411 141 0.134
regionalization GO:0003002 337 0.130
amine metabolic process GO:0009308 45 0.129
cell cell junction organization GO:0045216 72 0.129
organonitrogen compound catabolic process GO:1901565 264 0.128
ribonucleotide metabolic process GO:0009259 291 0.127
regulation of transferase activity GO:0051338 263 0.127
cell fate commitment GO:0045165 210 0.124
regulation of protein kinase activity GO:0045859 232 0.124
positive regulation of cellular amine metabolic process GO:0033240 5 0.123
regulation of lymphocyte differentiation GO:0045619 107 0.123
organelle assembly GO:0070925 177 0.122
activation of innate immune response GO:0002218 56 0.122
immune effector process GO:0002252 321 0.120
myeloid leukocyte activation GO:0002274 83 0.119
purine nucleoside triphosphate catabolic process GO:0009146 203 0.117
cd4 positive alpha beta t cell activation GO:0035710 45 0.116
mapk cascade GO:0000165 281 0.115
organophosphate catabolic process GO:0046434 232 0.114
negative regulation of lymphocyte activation GO:0051250 91 0.112
positive regulation of gtpase activity GO:0043547 85 0.110
stem cell differentiation GO:0048863 268 0.109
mitotic cell cycle GO:0000278 195 0.109
homeostasis of number of cells GO:0048872 210 0.104
myeloid leukocyte mediated immunity GO:0002444 42 0.103
myeloid cell differentiation GO:0030099 233 0.102
purine ribonucleotide catabolic process GO:0009154 208 0.101
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.100
regulation of cytokine production GO:0001817 266 0.099
negative regulation of cell activation GO:0050866 111 0.098
apoptotic signaling pathway GO:0097190 306 0.097
purine containing compound catabolic process GO:0072523 213 0.095
leukocyte activation involved in immune response GO:0002366 126 0.093
regulation of cellular catabolic process GO:0031329 242 0.091
positive regulation of nucleoside metabolic process GO:0045979 91 0.090
regulation of gtp catabolic process GO:0033124 113 0.088
mesodermal cell migration GO:0008078 4 0.087
activation of immune response GO:0002253 138 0.087
regulation of ras gtpase activity GO:0032318 88 0.086
cellular response to lipopolysaccharide GO:0071222 77 0.083
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.083
regulation of cellular ketone metabolic process GO:0010565 66 0.081
defense response to other organism GO:0098542 197 0.081
mitotic cell cycle process GO:1903047 159 0.081
t cell differentiation GO:0030217 174 0.078
cell activation involved in immune response GO:0002263 126 0.076
regulation of leukocyte differentiation GO:1902105 159 0.075
sensory organ morphogenesis GO:0090596 242 0.074
carbohydrate derivative biosynthetic process GO:1901137 183 0.073
hair follicle cell proliferation GO:0071335 3 0.073
regulation of leukocyte mediated immunity GO:0002703 104 0.073
positive regulation of transferase activity GO:0051347 167 0.072
regulation of cell activation GO:0050865 289 0.072
response to peptide GO:1901652 136 0.071
cell junction organization GO:0034330 77 0.070
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.069
regulation of kinase activity GO:0043549 249 0.069
positive regulation of protein phosphorylation GO:0001934 242 0.069
alpha beta t cell activation GO:0046631 91 0.069
mucopolysaccharide metabolic process GO:1903510 25 0.067
negative regulation of t cell activation GO:0050868 65 0.066
establishment of organelle localization GO:0051656 122 0.066
leukocyte differentiation GO:0002521 342 0.066
positive regulation of leukocyte differentiation GO:1902107 86 0.065
regulation of cd4 positive alpha beta t cell activation GO:2000514 24 0.065
positive regulation of map kinase activity GO:0043406 84 0.065
axonogenesis GO:0007409 274 0.063
peptidyl amino acid modification GO:0018193 336 0.063
cellular response to organonitrogen compound GO:0071417 145 0.062
innate immune response activating signal transduction GO:0002758 50 0.062
positive regulation of apoptotic process GO:0043065 217 0.062
gland development GO:0048732 330 0.061
positive regulation of cell activation GO:0050867 158 0.059
regulation of protein localization GO:0032880 231 0.058
response to radiation GO:0009314 165 0.058
negative regulation of leukocyte differentiation GO:1902106 51 0.058
actin cytoskeleton organization GO:0030036 220 0.058
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.057
regulation of cell motility GO:2000145 236 0.057
negative regulation of cytokine production GO:0001818 84 0.057
asymmetric neuroblast division GO:0055059 1 0.057
myeloid leukocyte differentiation GO:0002573 119 0.056
single organismal cell cell adhesion GO:0016337 131 0.056
negative regulation of protein metabolic process GO:0051248 282 0.056
response to insulin GO:0032868 100 0.055
leukocyte migration GO:0050900 124 0.055
regulation of alpha beta t cell differentiation GO:0046637 35 0.054
erk1 and erk2 cascade GO:0070371 77 0.054
cytokine production GO:0001816 319 0.054
endocytosis GO:0006897 168 0.053
positive regulation of mapk cascade GO:0043410 170 0.052
circadian rhythm GO:0007623 114 0.052
alpha beta t cell differentiation GO:0046632 69 0.052
mast cell mediated immunity GO:0002448 20 0.052
intracellular protein transport GO:0006886 204 0.052
myeloid cell activation involved in immune response GO:0002275 34 0.052
chromatin modification GO:0016568 187 0.052
regulation of cell adhesion GO:0030155 154 0.051
striated muscle tissue development GO:0014706 293 0.051
regulation of rho gtpase activity GO:0032319 58 0.051
regulation of secretion by cell GO:1903530 249 0.051
positive regulation of ras gtpase activity GO:0032320 65 0.051
regulation of hydrolase activity GO:0051336 246 0.050
embryonic organ morphogenesis GO:0048562 276 0.050
cellular response to molecule of bacterial origin GO:0071219 83 0.050
positive regulation of cell adhesion GO:0045785 80 0.049
regulation of t cell activation GO:0050863 170 0.049
regulation of protein catabolic process GO:0042176 108 0.048
negative regulation of protein modification process GO:0031400 163 0.048
regulation of binding GO:0051098 111 0.048
immune response regulating signaling pathway GO:0002764 125 0.048
actin filament bundle assembly GO:0051017 40 0.048
wnt signaling pathway GO:0016055 188 0.047
cytokine production involved in immune response GO:0002367 34 0.046
regulation of mast cell activation involved in immune response GO:0033006 17 0.046
positive regulation of lymphocyte differentiation GO:0045621 61 0.046
cellular response to peptide hormone stimulus GO:0071375 92 0.045
cell matrix adhesion GO:0007160 68 0.045
divalent inorganic cation transport GO:0072511 178 0.045
positive regulation of protein kinase activity GO:0045860 144 0.045
regulation of purine nucleotide metabolic process GO:1900542 169 0.044
cellular response to biotic stimulus GO:0071216 92 0.044
regulation of protein serine threonine kinase activity GO:0071900 157 0.043
myeloid dendritic cell differentiation GO:0043011 16 0.043
negative regulation of protein phosphorylation GO:0001933 126 0.043
divalent metal ion transport GO:0070838 172 0.043
histone modification GO:0016570 159 0.043
negative regulation of cellular amine metabolic process GO:0033239 1 0.043
regulation of mapk cascade GO:0043408 248 0.042
negative regulation of cellular protein metabolic process GO:0032269 247 0.042
regulation of toll like receptor signaling pathway GO:0034121 20 0.042
cellular response to growth factor stimulus GO:0071363 197 0.042
gliogenesis GO:0042063 141 0.042
negative regulation of t cell differentiation GO:0045581 23 0.042
lymphocyte activation involved in immune response GO:0002285 93 0.041
positive regulation of cellular component biogenesis GO:0044089 94 0.041
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.041
cellular lipid metabolic process GO:0044255 323 0.041
regulation of innate immune response GO:0045088 91 0.040
positive regulation of t cell differentiation GO:0045582 52 0.040
dendrite development GO:0016358 115 0.040
peptidyl serine modification GO:0018209 83 0.040
rho protein signal transduction GO:0007266 32 0.040
regulation of cytokine secretion GO:0050707 61 0.040
glycoprotein metabolic process GO:0009100 116 0.040
reactive oxygen species metabolic process GO:0072593 84 0.039
peptidyl serine phosphorylation GO:0018105 74 0.039
negative regulation of phosphorus metabolic process GO:0010563 184 0.039
regulation of apoptotic signaling pathway GO:2001233 197 0.039
peptidyl lysine modification GO:0018205 77 0.039
negative regulation of phosphate metabolic process GO:0045936 184 0.039
mitochondrion distribution GO:0048311 4 0.039
cerebral cortex radially oriented cell migration GO:0021799 31 0.039
stem cell development GO:0048864 219 0.039
response to lipopolysaccharide GO:0032496 128 0.039
positive regulation of organelle organization GO:0010638 128 0.038
multicellular organismal signaling GO:0035637 91 0.038
positive regulation of cell development GO:0010720 237 0.038
response to growth factor GO:0070848 198 0.038
regulation of endocytosis GO:0030100 69 0.038
negative regulation of lymphocyte differentiation GO:0045620 32 0.038
interferon beta biosynthetic process GO:0045350 4 0.038
cellularization GO:0007349 1 0.038
b cell activation GO:0042113 161 0.037
cation homeostasis GO:0055080 212 0.037
chromatin organization GO:0006325 206 0.037
camera type eye development GO:0043010 266 0.037
regulation of alpha beta t cell activation GO:0046634 53 0.037
blood vessel morphogenesis GO:0048514 285 0.037
multicellular organism growth GO:0035264 161 0.037
toll like receptor 9 signaling pathway GO:0034162 6 0.037
negative regulation of synapse assembly GO:0051964 3 0.036
epithelial cell development GO:0002064 159 0.036
production of molecular mediator of immune response GO:0002440 103 0.036
protein acylation GO:0043543 64 0.036
positive regulation of innate immune response GO:0045089 80 0.036
sequestering of metal ion GO:0051238 19 0.036
regulation of cell migration GO:0030334 219 0.036
single organism cell adhesion GO:0098602 156 0.036
protein localization to organelle GO:0033365 185 0.036
posttranscriptional regulation of gene expression GO:0010608 155 0.035
positive regulation of kinase activity GO:0033674 155 0.035
positive regulation of immune effector process GO:0002699 107 0.035
regulation of neuron projection development GO:0010975 169 0.035
cellular response to lipid GO:0071396 145 0.035
adaptive immune response GO:0002250 155 0.035
establishment or maintenance of cell polarity GO:0007163 86 0.034
response to peptide hormone GO:0043434 127 0.034
regulation of lymphocyte activation GO:0051249 240 0.034
cell division GO:0051301 120 0.034
positive regulation of nucleotide catabolic process GO:0030813 88 0.034
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.034
response to organonitrogen compound GO:0010243 246 0.034
anatomical structure arrangement GO:0048532 20 0.034
activation of mapk activity involved in innate immune response GO:0035419 2 0.034
mast cell activation involved in immune response GO:0002279 20 0.034
mast cell degranulation GO:0043303 19 0.034
leukocyte cell cell adhesion GO:0007159 14 0.034
cation transport GO:0006812 399 0.033
phospholipid metabolic process GO:0006644 87 0.033
hematopoietic progenitor cell differentiation GO:0002244 143 0.033
oxidation reduction process GO:0055114 342 0.033
exocytosis GO:0006887 121 0.033
cellular component assembly involved in morphogenesis GO:0010927 139 0.033
glycosylation GO:0070085 62 0.033
lymphocyte apoptotic process GO:0070227 54 0.033
regulation of defense response GO:0031347 233 0.033
myeloid cell homeostasis GO:0002262 114 0.032
regulation of cell cycle GO:0051726 281 0.032
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.032
skin development GO:0043588 220 0.032
positive regulation of programmed cell death GO:0043068 218 0.032
dorsal ventral axon guidance GO:0033563 3 0.032
regulation of hair follicle cell proliferation GO:0071336 2 0.032
macrophage differentiation GO:0030225 20 0.031
connective tissue development GO:0061448 179 0.031
positive regulation of neuron projection development GO:0010976 79 0.031
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.031
interspecies interaction between organisms GO:0044419 83 0.031
establishment of vesicle localization GO:0051650 81 0.031
regulation of secretion GO:0051046 274 0.031
skeletal muscle organ development GO:0060538 163 0.030
negative regulation of apoptotic signaling pathway GO:2001234 104 0.030
regulation of histone acetylation GO:0035065 19 0.030
neural precursor cell proliferation GO:0061351 121 0.030
regulation of cellular component biogenesis GO:0044087 181 0.030
actin filament organization GO:0007015 113 0.030
negative regulation of t helper 1 cell differentiation GO:0045626 3 0.030
cardiac muscle tissue development GO:0048738 130 0.029
bone development GO:0060348 120 0.029
regulation of mast cell activation GO:0033003 21 0.029
exocrine system development GO:0035272 45 0.029
digestive tract morphogenesis GO:0048546 147 0.029
regulation of histone modification GO:0031056 56 0.029
positive regulation of defense response GO:0031349 124 0.028
compound eye development GO:0048749 1 0.028
interleukin 6 production GO:0032635 58 0.028
adherens junction organization GO:0034332 28 0.028
muscle cell development GO:0055001 133 0.028
synapse assembly GO:0007416 56 0.028
positive regulation of cell projection organization GO:0031346 95 0.028
signal transduction by p53 class mediator GO:0072331 51 0.028
regulation of ral gtpase activity GO:0032315 4 0.028
positive regulation of neuron differentiation GO:0045666 141 0.028
methylation GO:0032259 134 0.028
ion transmembrane transport GO:0034220 361 0.028
cellular metal ion homeostasis GO:0006875 151 0.028
neuron projection guidance GO:0097485 141 0.027
asymmetric stem cell division GO:0098722 3 0.027
digestive system development GO:0055123 200 0.027
leukocyte homeostasis GO:0001776 79 0.027
developmental maturation GO:0021700 193 0.027
forebrain generation of neurons GO:0021872 63 0.027
internal protein amino acid acetylation GO:0006475 42 0.027
positive regulation of membrane protein ectodomain proteolysis GO:0051044 3 0.027
cellular response to peptide GO:1901653 92 0.027
neuron migration GO:0001764 122 0.027
regulation of interferon beta biosynthetic process GO:0045357 4 0.027
t cell activation involved in immune response GO:0002286 43 0.026
glial cell differentiation GO:0010001 131 0.026
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.026
negative regulation of ras protein signal transduction GO:0046580 18 0.026
leukocyte degranulation GO:0043299 27 0.026
negative regulation of secretion GO:0051048 61 0.026
organonitrogen compound biosynthetic process GO:1901566 192 0.026
regulation of response to wounding GO:1903034 189 0.026
response to light stimulus GO:0009416 135 0.026
regulation of chromosome organization GO:0033044 83 0.026
phagocytosis GO:0006909 66 0.026
regulation of t helper 1 cell differentiation GO:0045625 7 0.026
positive regulation of cell death GO:0010942 224 0.026
positive regulation of lymphocyte activation GO:0051251 140 0.026
cytoplasmic transport GO:0016482 234 0.026
regulation of myeloid cell differentiation GO:0045637 96 0.026
calcium ion transport GO:0006816 159 0.026
glycoprotein biosynthetic process GO:0009101 89 0.026
epidermis development GO:0008544 187 0.026
t cell proliferation GO:0042098 120 0.025
lysosome localization GO:0032418 20 0.025
regulation of protein transport GO:0051223 163 0.025
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.025
response to extracellular stimulus GO:0009991 127 0.025
digestive tract development GO:0048565 190 0.025
positive regulation of secretion by cell GO:1903532 114 0.025
membrane organization GO:0061024 245 0.025
cell type specific apoptotic process GO:0097285 268 0.025
positive regulation of cytokine biosynthetic process GO:0042108 40 0.025
positive regulation of myeloid cell differentiation GO:0045639 43 0.025
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.024
respiratory system development GO:0060541 190 0.024
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.024
cartilage development GO:0051216 140 0.024
negative regulation of myeloid cell differentiation GO:0045638 38 0.024
striated muscle cell development GO:0055002 125 0.024
regulation of adaptive immune response GO:0002819 90 0.024
regulation of lamellipodium assembly GO:0010591 3 0.024
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.024
positive regulation of nervous system development GO:0051962 221 0.024
engulfment of apoptotic cell GO:0043652 3 0.024
negative regulation of secretion by cell GO:1903531 54 0.024
tissue remodeling GO:0048771 102 0.024
wound healing GO:0042060 157 0.024
positive regulation of nucleotide metabolic process GO:0045981 114 0.024
mesenchymal cell development GO:0014031 93 0.024
myotube differentiation GO:0014902 105 0.023
macromolecule catabolic process GO:0009057 281 0.023
chemotaxis GO:0006935 247 0.023
response to transforming growth factor beta GO:0071559 88 0.023
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.023
positive regulation of cytokine production GO:0001819 174 0.023
positive regulation of hydrolase activity GO:0051345 148 0.023
cerebellar granule cell precursor tangential migration GO:0021935 1 0.023
negative regulation of growth GO:0045926 99 0.023
canonical wnt signaling pathway GO:0060070 130 0.023
protein modification by small protein conjugation or removal GO:0070647 207 0.023
positive regulation of thymocyte migration GO:2000412 2 0.023
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.023
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.023
positive regulation of leukocyte proliferation GO:0070665 73 0.023
cellular response to calcium ion GO:0071277 14 0.023
protein ubiquitination GO:0016567 171 0.023
extrinsic apoptotic signaling pathway GO:0097191 126 0.023
regulation of cytokine production involved in immune response GO:0002718 26 0.023
positive regulation of leukocyte apoptotic process GO:2000108 21 0.023
toll like receptor 7 signaling pathway GO:0034154 4 0.022
positive regulation of lamellipodium organization GO:1902745 3 0.022
regulation of leukocyte apoptotic process GO:2000106 56 0.022
endomembrane system organization GO:0010256 147 0.022
peptidyl lysine acetylation GO:0018394 45 0.022
activation of rac gtpase activity GO:0032863 2 0.022
positive regulation of protein secretion GO:0050714 52 0.022
epithelial cell morphogenesis GO:0003382 41 0.022
regulation of protein secretion GO:0050708 82 0.022
lymphocyte proliferation GO:0046651 164 0.022
regulation of erk1 and erk2 cascade GO:0070372 71 0.022
negative regulation of erk1 and erk2 cascade GO:0070373 21 0.022
regulation of intracellular transport GO:0032386 159 0.022
negative regulation of immune effector process GO:0002698 55 0.022
mesenchymal cell differentiation GO:0048762 107 0.022
striated muscle myosin thick filament assembly GO:0071688 1 0.022
response to hypoxia GO:0001666 58 0.022
protein glycosylation GO:0006486 55 0.021
neutrophil chemotaxis GO:0030593 36 0.021
cytokine mediated signaling pathway GO:0019221 115 0.021
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.021
establishment or maintenance of bipolar cell polarity GO:0061245 21 0.021
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.021
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.021
negative regulation of synaptic vesicle transport GO:1902804 3 0.021
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.021
regulation of chromatin modification GO:1903308 57 0.021
embryonic olfactory bulb interneuron precursor migration GO:0021831 2 0.021
negative regulation of immune system process GO:0002683 209 0.021
regulation of cell substrate adhesion GO:0010810 73 0.021
angiogenesis GO:0001525 201 0.021
erythrocyte differentiation GO:0030218 88 0.021
internal peptidyl lysine acetylation GO:0018393 42 0.021
regulation of inflammatory response GO:0050727 147 0.021
muscle tissue development GO:0060537 308 0.021
negative regulation of granulocyte differentiation GO:0030853 3 0.021
lipid biosynthetic process GO:0008610 179 0.020
regulation of interleukin 6 production GO:0032675 55 0.020
neuron apoptotic process GO:0051402 142 0.020
negative regulation of viral process GO:0048525 23 0.020
cellular calcium ion homeostasis GO:0006874 119 0.020
regulation of peptidyl lysine acetylation GO:2000756 22 0.020
pattern recognition receptor signaling pathway GO:0002221 47 0.020
thymocyte migration GO:0072679 2 0.020
intestinal epithelial structure maintenance GO:0060729 4 0.020
stem cell proliferation GO:0072089 117 0.020
rac protein signal transduction GO:0016601 13 0.020
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.020
regulation of homeostatic process GO:0032844 182 0.020
learning GO:0007612 98 0.020
gastrulation GO:0007369 116 0.020
transmission of nerve impulse GO:0019226 76 0.020
peripheral nervous system development GO:0007422 53 0.020
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.020
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.019
germ cell development GO:0007281 185 0.019
immune response activating signal transduction GO:0002757 116 0.019
learning or memory GO:0007611 148 0.019
neuron projection extension GO:1990138 64 0.019
regulation of map kinase activity GO:0043405 120 0.019
interleukin 13 secretion GO:0072611 2 0.019
regulation of cellular response to stress GO:0080135 159 0.019
lymphocyte homeostasis GO:0002260 64 0.019
positive regulation of rho gtpase activity GO:0032321 41 0.019
actin filament based movement GO:0030048 23 0.019
female sex differentiation GO:0046660 84 0.019
negative regulation of synaptic vesicle exocytosis GO:2000301 3 0.019
motor neuron axon guidance GO:0008045 26 0.019
skin morphogenesis GO:0043589 38 0.019
regulation of mitotic cell cycle GO:0007346 126 0.019
negative regulation of interleukin 10 secretion GO:2001180 2 0.019
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.019
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.019
forebrain cell migration GO:0021885 58 0.019
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.019
ear development GO:0043583 200 0.019
macromolecule glycosylation GO:0043413 55 0.019
body morphogenesis GO:0010171 45 0.019
regulation of leukocyte proliferation GO:0070663 121 0.019
development of primary female sexual characteristics GO:0046545 73 0.018
regulation of organelle organization GO:0033043 289 0.018
female gamete generation GO:0007292 74 0.018
tolerance induction to self antigen GO:0002513 4 0.018
regulation of peptidyl serine phosphorylation GO:0033135 39 0.018
myosin filament assembly GO:0031034 2 0.018
cerebral cortex cell migration GO:0021795 44 0.018
regulation of t cell proliferation GO:0042129 92 0.018
cellular response to external stimulus GO:0071496 88 0.018
regulation of wnt signaling pathway GO:0030111 123 0.018
antigen receptor mediated signaling pathway GO:0050851 64 0.018
substrate adhesion dependent cell spreading GO:0034446 30 0.018
nuclear division GO:0000280 158 0.018
divalent inorganic cation homeostasis GO:0072507 138 0.018
positive regulation of leukocyte mediated immunity GO:0002705 70 0.018
hexose metabolic process GO:0019318 98 0.018
positive regulation of protein transport GO:0051222 93 0.018
reactive oxygen species biosynthetic process GO:1903409 8 0.018
cell chemotaxis GO:0060326 81 0.018
cellular ion homeostasis GO:0006873 165 0.018
modification by symbiont of host morphology or physiology GO:0044003 4 0.018
pma inducible membrane protein ectodomain proteolysis GO:0051088 1 0.018
regulation of organ morphogenesis GO:2000027 144 0.018
epidermis morphogenesis GO:0048730 33 0.018
intracellular receptor signaling pathway GO:0030522 74 0.017

Plekho2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.034
musculoskeletal system disease DOID:17 0 0.034
cancer DOID:162 0 0.021
disease of cellular proliferation DOID:14566 0 0.021
organ system cancer DOID:0050686 0 0.021
immune system cancer DOID:0060083 0 0.020
hematologic cancer DOID:2531 0 0.020