Mus musculus

0 known processes

Hephl1

hephaestin-like 1

(Aliases: Gm509,Zp,zyklopen)

Hephl1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transmembrane transport GO:0055085 412 0.080
cellular amine metabolic process GO:0044106 44 0.076
regulation of response to wounding GO:1903034 189 0.066
negative regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061179 4 0.060
regulation of cellular ketone metabolic process GO:0010565 66 0.056
amine metabolic process GO:0009308 45 0.054
ion transmembrane transport GO:0034220 361 0.049
cellular ketone metabolic process GO:0042180 84 0.048
anion transport GO:0006820 177 0.048
regulation of cellular amino acid metabolic process GO:0006521 5 0.045
apoptotic signaling pathway GO:0097190 306 0.043
cell adhesion GO:0007155 329 0.043
cellular homeostasis GO:0019725 240 0.042
extracellular structure organization GO:0043062 148 0.042
striated muscle tissue development GO:0014706 293 0.042
regulation of anatomical structure size GO:0090066 178 0.041
cation transmembrane transport GO:0098655 266 0.041
protein catabolic process GO:0030163 221 0.041
cellular lipid metabolic process GO:0044255 323 0.040
response to organonitrogen compound GO:0010243 246 0.039
blood vessel morphogenesis GO:0048514 285 0.039
regulation of protein localization GO:0032880 231 0.038
extracellular matrix organization GO:0030198 147 0.037
negative regulation of cell proliferation GO:0008285 296 0.036
oxidation reduction process GO:0055114 342 0.036
Human
lipid biosynthetic process GO:0008610 179 0.036
macromolecule catabolic process GO:0009057 281 0.035
axonogenesis GO:0007409 274 0.035
regulation of cellular amine metabolic process GO:0033238 20 0.034
regulation of cell cycle GO:0051726 281 0.034
developmental maturation GO:0021700 193 0.033
negative regulation of protein metabolic process GO:0051248 282 0.033
cellular amino acid metabolic process GO:0006520 103 0.033
developmental growth involved in morphogenesis GO:0060560 138 0.032
cytokine production GO:0001816 319 0.032
cation transport GO:0006812 399 0.032
skin development GO:0043588 220 0.031
purine containing compound metabolic process GO:0072521 311 0.031
regulation of defense response GO:0031347 233 0.031
mapk cascade GO:0000165 281 0.031
skeletal system development GO:0001501 356 0.030
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.030
cell type specific apoptotic process GO:0097285 268 0.030
ossification GO:0001503 216 0.030
interleukin 8 secretion GO:0072606 3 0.030
alcohol metabolic process GO:0006066 116 0.030
nucleobase containing small molecule metabolic process GO:0055086 352 0.029
inorganic cation transmembrane transport GO:0098662 207 0.029
purine nucleotide metabolic process GO:0006163 302 0.028
protein localization to membrane GO:0072657 108 0.028
regulation of body fluid levels GO:0050878 162 0.028
hematopoietic progenitor cell differentiation GO:0002244 143 0.028
actin cytoskeleton organization GO:0030036 220 0.028
negative regulation of response to wounding GO:1903035 77 0.027
peptidyl amino acid modification GO:0018193 336 0.027
monocarboxylic acid metabolic process GO:0032787 191 0.026
aromatic compound catabolic process GO:0019439 286 0.026
blood circulation GO:0008015 195 0.026
leukocyte differentiation GO:0002521 342 0.026
regulation of system process GO:0044057 200 0.025
protein ubiquitination GO:0016567 171 0.025
fat cell differentiation GO:0045444 160 0.025
sensory perception GO:0007600 245 0.025
regulation of membrane potential GO:0042391 192 0.025
cellular response to hormone stimulus GO:0032870 150 0.025
protein maturation GO:0051604 176 0.025
microtubule based process GO:0007017 236 0.024
epithelial tube morphogenesis GO:0060562 303 0.024
nucleotide metabolic process GO:0009117 332 0.024
lymphocyte differentiation GO:0030098 242 0.024
epithelial cell proliferation GO:0050673 174 0.024
fatty acid metabolic process GO:0006631 121 0.024
regulation of cytokine production GO:0001817 266 0.023
regulation of cellular component biogenesis GO:0044087 181 0.023
regulation of transferase activity GO:0051338 263 0.023
regulation of kinase activity GO:0043549 249 0.023
regulation of lipid metabolic process GO:0019216 118 0.023
epidermis development GO:0008544 187 0.023
wnt signaling pathway GO:0016055 188 0.022
purine nucleoside metabolic process GO:0042278 241 0.022
endomembrane system organization GO:0010256 147 0.022
extrinsic apoptotic signaling pathway GO:0097191 126 0.022
regulation of interleukin 8 secretion GO:2000482 2 0.022
ribonucleotide metabolic process GO:0009259 291 0.022
regulation of feeding behavior GO:0060259 3 0.022
small gtpase mediated signal transduction GO:0007264 97 0.022
generation of precursor metabolites and energy GO:0006091 103 0.021
metal ion homeostasis GO:0055065 189 0.021
wound healing GO:0042060 157 0.021
protein modification by small protein conjugation or removal GO:0070647 207 0.021
membrane organization GO:0061024 245 0.021
skeletal muscle organ development GO:0060538 163 0.021
ribose phosphate metabolic process GO:0019693 291 0.021
negative regulation of cellular protein metabolic process GO:0032269 247 0.021
cellular response to cytokine stimulus GO:0071345 189 0.021
protein modification by small protein conjugation GO:0032446 187 0.021
cellular macromolecule catabolic process GO:0044265 206 0.021
regulation of inflammatory response GO:0050727 147 0.021
gland development GO:0048732 330 0.021
negative regulation of cellular component organization GO:0051129 194 0.021
positive regulation of protein modification process GO:0031401 299 0.020
response to organic cyclic compound GO:0014070 198 0.020
cytoplasmic transport GO:0016482 234 0.020
regulation of interleukin 8 production GO:0032677 3 0.020
development of primary male sexual characteristics GO:0046546 88 0.020
nucleoside phosphate metabolic process GO:0006753 338 0.020
gonad development GO:0008406 141 0.020
synaptic transmission GO:0007268 329 0.020
divalent inorganic cation transport GO:0072511 178 0.020
appendage morphogenesis GO:0035107 149 0.020
interleukin 8 production GO:0032637 4 0.020
organic cyclic compound catabolic process GO:1901361 295 0.020
regulation of organelle organization GO:0033043 289 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.020
cellular nitrogen compound catabolic process GO:0044270 280 0.019
muscle cell differentiation GO:0042692 261 0.019
mitotic cell cycle process GO:1903047 159 0.019
regulation of lymphocyte activation GO:0051249 240 0.019
regulation of hydrolase activity GO:0051336 246 0.019
small molecule biosynthetic process GO:0044283 132 0.019
positive regulation of cellular amine metabolic process GO:0033240 5 0.019
cell growth GO:0016049 130 0.019
male gonad development GO:0008584 88 0.019
regulation of cell cycle process GO:0010564 160 0.019
organic hydroxy compound metabolic process GO:1901615 203 0.019
heterocycle catabolic process GO:0046700 280 0.019
morphogenesis of a branching epithelium GO:0061138 193 0.019
microtubule cytoskeleton organization GO:0000226 157 0.019
organonitrogen compound catabolic process GO:1901565 264 0.019
ear development GO:0043583 200 0.019
muscle system process GO:0003012 141 0.019
intracellular protein transport GO:0006886 204 0.019
protein localization to organelle GO:0033365 185 0.018
meiotic cell cycle GO:0051321 122 0.018
male sex differentiation GO:0046661 109 0.018
cellular protein catabolic process GO:0044257 155 0.018
cellular response to organonitrogen compound GO:0071417 145 0.018
regulation of secretion GO:0051046 274 0.018
nucleoside triphosphate metabolic process GO:0009141 230 0.018
response to peptide hormone GO:0043434 127 0.018
regulation of cellular catabolic process GO:0031329 242 0.018
cell junction organization GO:0034330 77 0.018
negative regulation of cell development GO:0010721 169 0.018
nucleoside catabolic process GO:0009164 206 0.018
rho protein signal transduction GO:0007266 32 0.018
chemotaxis GO:0006935 247 0.018
regulation of transmembrane transport GO:0034762 128 0.018
purine ribonucleotide metabolic process GO:0009150 290 0.018
appendage development GO:0048736 166 0.017
regulation of mapk cascade GO:0043408 248 0.017
negative regulation of defense response GO:0031348 77 0.017
positive regulation of nervous system development GO:0051962 221 0.017
lipid catabolic process GO:0016042 69 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.017
regulation of ossification GO:0030278 112 0.017
ubiquitin dependent protein catabolic process GO:0006511 129 0.017
skeletal system morphogenesis GO:0048705 203 0.017
embryonic organ morphogenesis GO:0048562 276 0.017
inflammatory response GO:0006954 244 0.017
organophosphate catabolic process GO:0046434 232 0.017
angiogenesis GO:0001525 201 0.017
myeloid leukocyte differentiation GO:0002573 119 0.017
forebrain development GO:0030900 302 0.017
cellular response to lipid GO:0071396 145 0.017
calcium ion homeostasis GO:0055074 127 0.017
cellular protein complex assembly GO:0043623 116 0.017
cellular metal ion homeostasis GO:0006875 151 0.017
negative regulation of cellular amine metabolic process GO:0033239 1 0.016
maintenance of location GO:0051235 89 0.016
anatomical structure homeostasis GO:0060249 145 0.016
carbohydrate metabolic process GO:0005975 230 0.016
nuclear division GO:0000280 158 0.016
ribonucleoside metabolic process GO:0009119 245 0.016
purine nucleoside catabolic process GO:0006152 205 0.016
regulation of cell activation GO:0050865 289 0.016
regulation of cell motility GO:2000145 236 0.016
cell division GO:0051301 120 0.016
positive regulation of neuron differentiation GO:0045666 141 0.016
cell maturation GO:0048469 127 0.016
nucleoside phosphate catabolic process GO:1901292 222 0.016
lipid homeostasis GO:0055088 63 0.016
posttranscriptional regulation of gene expression GO:0010608 155 0.016
organic anion transport GO:0015711 137 0.016
cellular divalent inorganic cation homeostasis GO:0072503 127 0.016
fertilization GO:0009566 127 0.016
nucleoside metabolic process GO:0009116 246 0.015
ribonucleoside catabolic process GO:0042454 206 0.015
action potential GO:0001508 78 0.015
cellular chemical homeostasis GO:0055082 215 0.015
sodium ion transport GO:0006814 73 0.015
cellular response to organic cyclic compound GO:0071407 87 0.015
negative regulation of inflammatory response GO:0050728 61 0.015
protein targeting GO:0006605 143 0.015
regulation of cellular component size GO:0032535 121 0.015
glycosyl compound metabolic process GO:1901657 246 0.015
negative regulation of cell cycle GO:0045786 123 0.015
t cell differentiation GO:0030217 174 0.015
regulation of mitotic cell cycle GO:0007346 126 0.015
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.015
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.015
response to nutrient levels GO:0031667 109 0.015
glucose homeostasis GO:0042593 128 0.015
placenta development GO:0001890 140 0.015
plasma membrane organization GO:0007009 90 0.015
regulation of reproductive process GO:2000241 66 0.015
regulation of protein transport GO:0051223 163 0.015
muscle tissue development GO:0060537 308 0.015
response to extracellular stimulus GO:0009991 127 0.015
neuron projection extension GO:1990138 64 0.015
ribonucleoside triphosphate metabolic process GO:0009199 220 0.015
regulation of establishment of protein localization GO:0070201 181 0.014
mitotic cell cycle GO:0000278 195 0.014
epithelial cell development GO:0002064 159 0.014
defecation GO:0030421 1 0.014
synapse organization GO:0050808 125 0.014
organelle assembly GO:0070925 177 0.014
regulation of intracellular transport GO:0032386 159 0.014
regulation of cytoskeleton organization GO:0051493 122 0.014
purine ribonucleoside catabolic process GO:0046130 205 0.014
regulation of heart contraction GO:0008016 77 0.014
regulation of purine nucleotide metabolic process GO:1900542 169 0.014
carbohydrate derivative catabolic process GO:1901136 231 0.014
regulation of transforming growth factor beta secretion GO:2001201 1 0.014
cellular response to growth factor stimulus GO:0071363 197 0.014
regulation of cell growth GO:0001558 91 0.014
purine ribonucleoside metabolic process GO:0046128 241 0.014
spermatogenesis GO:0007283 284 0.014
palate development GO:0060021 76 0.014
development of primary sexual characteristics GO:0045137 143 0.014
leukocyte proliferation GO:0070661 172 0.014
central nervous system neuron differentiation GO:0021953 162 0.014
positive regulation of growth GO:0045927 104 0.014
response to molecule of bacterial origin GO:0002237 143 0.014
glycerolipid metabolic process GO:0046486 122 0.014
negative regulation of protein modification process GO:0031400 163 0.014
regulation of proteolysis GO:0030162 164 0.014
nucleoside triphosphate catabolic process GO:0009143 205 0.014
bone development GO:0060348 120 0.014
embryonic limb morphogenesis GO:0030326 126 0.014
negative regulation of molecular function GO:0044092 258 0.013
inorganic ion transmembrane transport GO:0098660 234 0.013
carbohydrate derivative biosynthetic process GO:1901137 183 0.013
regulation of cell projection organization GO:0031344 206 0.013
regionalization GO:0003002 337 0.013
learning or memory GO:0007611 148 0.013
regulation of nucleotide metabolic process GO:0006140 169 0.013
multicellular organismal signaling GO:0035637 91 0.013
purine ribonucleotide catabolic process GO:0009154 208 0.013
protein localization to nucleus GO:0034504 121 0.013
sequestering of calcium ion GO:0051208 18 0.013
regulation of ion transport GO:0043269 215 0.013
myeloid cell differentiation GO:0030099 233 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.013
positive regulation of cellular catabolic process GO:0031331 148 0.013
modification dependent macromolecule catabolic process GO:0043632 133 0.013
female sex differentiation GO:0046660 84 0.013
positive regulation of apoptotic process GO:0043065 217 0.013
nitrogen compound transport GO:0071705 271 0.013
organonitrogen compound biosynthetic process GO:1901566 192 0.013
norepinephrine transport GO:0015874 2 0.013
innate immune response GO:0045087 157 0.013
limb development GO:0060173 166 0.013
regulation of neuron differentiation GO:0045664 281 0.013
cellular ion homeostasis GO:0006873 165 0.013
urogenital system development GO:0001655 261 0.013
calcium ion transport GO:0006816 159 0.013
protein secretion GO:0009306 111 0.013
response to light stimulus GO:0009416 135 0.013
female meiosis chromosome segregation GO:0016321 1 0.013
cellular alcohol biosynthetic process GO:0044108 3 0.013
digestion GO:0007586 40 0.013
retina development in camera type eye GO:0060041 119 0.012
canonical wnt signaling pathway GO:0060070 130 0.012
digestive tract morphogenesis GO:0048546 147 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.012
regulation of cell adhesion GO:0030155 154 0.012
positive regulation of secretion GO:0051047 130 0.012
cell recognition GO:0008037 83 0.012
positive regulation of nucleotide metabolic process GO:0045981 114 0.012
ras protein signal transduction GO:0007265 77 0.012
divalent inorganic cation homeostasis GO:0072507 138 0.012
endocrine system development GO:0035270 98 0.012
tube formation GO:0035148 140 0.012
positive regulation of cellular component biogenesis GO:0044089 94 0.012
branching morphogenesis of an epithelial tube GO:0048754 159 0.012
small molecule catabolic process GO:0044282 71 0.012
cardiac muscle tissue development GO:0048738 130 0.012
meiotic nuclear division GO:0007126 115 0.012
regulation of ion transmembrane transport GO:0034765 119 0.012
striated muscle contraction GO:0006941 45 0.012
divalent metal ion transport GO:0070838 172 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.012
positive regulation of transferase activity GO:0051347 167 0.012
cellular response to biotic stimulus GO:0071216 92 0.012
t cell activation GO:0042110 289 0.012
positive regulation of interleukin 8 production GO:0032757 2 0.012
modification dependent protein catabolic process GO:0019941 133 0.012
regulation of cell size GO:0008361 72 0.012
multicellular organism growth GO:0035264 161 0.012
metencephalon development GO:0022037 89 0.012
cognition GO:0050890 149 0.012
purine containing compound catabolic process GO:0072523 213 0.012
cellular response to nutrient levels GO:0031669 64 0.012
developmental cell growth GO:0048588 84 0.012
neural tube formation GO:0001841 108 0.012
rhythmic process GO:0048511 174 0.012
organophosphate biosynthetic process GO:0090407 122 0.012
nucleotide catabolic process GO:0009166 217 0.012
positive regulation of cytokine production GO:0001819 174 0.012
hemostasis GO:0007599 78 0.012
response to radiation GO:0009314 165 0.012
cation homeostasis GO:0055080 212 0.012
endocytosis GO:0006897 168 0.012
positive regulation of protein transport GO:0051222 93 0.012
response to peptide GO:1901652 136 0.012
immune effector process GO:0002252 321 0.012
circulatory system process GO:0003013 197 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.011
nucleocytoplasmic transport GO:0006913 139 0.011
purine nucleotide catabolic process GO:0006195 211 0.011
regulation of bmp signaling pathway GO:0030510 60 0.011
norepinephrine secretion GO:0048243 2 0.011
purine nucleoside triphosphate catabolic process GO:0009146 203 0.011
regulation of cell substrate adhesion GO:0010810 73 0.011
embryonic placenta development GO:0001892 98 0.011
regulation of satellite cell activation involved in skeletal muscle regeneration GO:0014717 3 0.011
purine nucleoside triphosphate metabolic process GO:0009144 226 0.011
respiratory system development GO:0060541 190 0.011
establishment of blood nerve barrier GO:0008065 3 0.011
morphogenesis of embryonic epithelium GO:0016331 159 0.011
transmission of nerve impulse GO:0019226 76 0.011
negative regulation of nervous system development GO:0051961 156 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.011
organelle fission GO:0048285 170 0.011
germ cell development GO:0007281 185 0.011
regulation of cellular protein catabolic process GO:1903362 61 0.011
axon guidance GO:0007411 141 0.011
purine ribonucleotide biosynthetic process GO:0009152 59 0.011
regulation of blood circulation GO:1903522 93 0.011
negative regulation of growth GO:0045926 99 0.011
protein localization to plasma membrane GO:0072659 57 0.011
mesenchymal cell development GO:0014031 93 0.011
regulation of protein catabolic process GO:0042176 108 0.011
camera type eye development GO:0043010 266 0.011
phospholipid metabolic process GO:0006644 87 0.011
midgut development GO:0007494 4 0.011
bone mineralization GO:0030282 54 0.011
response to growth factor GO:0070848 198 0.011
regulation of cytoplasmic transport GO:1903649 112 0.011
muscle cell development GO:0055001 133 0.011
somatotropin secreting cell differentiation GO:0060126 4 0.011
hair cycle GO:0042633 90 0.011
negative regulation of immune system process GO:0002683 209 0.011
morphogenesis of a branching structure GO:0001763 203 0.011
nuclear transport GO:0051169 139 0.011
positive regulation of cell death GO:0010942 224 0.011
response to inorganic substance GO:0010035 96 0.011
g protein coupled receptor signaling pathway GO:0007186 243 0.011
cellular response to peptide hormone stimulus GO:0071375 92 0.011
muscle contraction GO:0006936 101 0.011
steroid metabolic process GO:0008202 119 0.011
negative regulation of phosphorus metabolic process GO:0010563 184 0.011
cardiac chamber development GO:0003205 108 0.011
kidney development GO:0001822 213 0.011
positive regulation of secretion by cell GO:1903532 114 0.011
cellular response to external stimulus GO:0071496 88 0.011
epithelial tube formation GO:0072175 130 0.011
cerebellum development GO:0021549 77 0.011
tube closure GO:0060606 91 0.011
wnt signaling pathway calcium modulating pathway GO:0007223 2 0.011
cell cell junction organization GO:0045216 72 0.011
multi multicellular organism process GO:0044706 109 0.011
protein processing GO:0016485 163 0.011
ear morphogenesis GO:0042471 118 0.011
negative regulation of phosphorylation GO:0042326 166 0.011
negative regulation of hormone metabolic process GO:0032351 4 0.011
satellite cell activation involved in skeletal muscle regeneration GO:0014901 3 0.011
male gamete generation GO:0048232 285 0.011
establishment of protein localization to organelle GO:0072594 118 0.010
cytokine mediated signaling pathway GO:0019221 115 0.010
development of primary female sexual characteristics GO:0046545 73 0.010
organ growth GO:0035265 117 0.010
cell fate commitment GO:0045165 210 0.010
nucleoside monophosphate metabolic process GO:0009123 85 0.010
regulation of protein kinase activity GO:0045859 232 0.010
regulation of cell cycle phase transition GO:1901987 77 0.010
embryonic epithelial tube formation GO:0001838 130 0.010
regulation of muscle contraction GO:0006937 49 0.010
positive regulation of apoptotic signaling pathway GO:2001235 95 0.010
neuron projection guidance GO:0097485 141 0.010
regulation of secretion by cell GO:1903530 249 0.010
heart process GO:0003015 94 0.010
embryonic appendage morphogenesis GO:0035113 126 0.010
myoblast differentiation GO:0045445 52 0.010
inner ear morphogenesis GO:0042472 101 0.010
fat soluble vitamin biosynthetic process GO:0042362 4 0.010
ribonucleotide catabolic process GO:0009261 208 0.010
artery development GO:0060840 53 0.010
regulation of neuron projection development GO:0010975 169 0.010
sensory organ morphogenesis GO:0090596 242 0.010
somitogenesis GO:0001756 69 0.010
regulation of mitotic cell cycle phase transition GO:1901990 73 0.010
regulation of striated muscle cell differentiation GO:0051153 81 0.010
regulation of lymphocyte proliferation GO:0050670 117 0.010
homeostasis of number of cells GO:0048872 210 0.010
nuclear import GO:0051170 95 0.010
b cell activation GO:0042113 161 0.010
actin filament organization GO:0007015 113 0.010
cellular carbohydrate metabolic process GO:0044262 119 0.010
neuron apoptotic process GO:0051402 142 0.010
sequestering of metal ion GO:0051238 19 0.010

Hephl1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.026
disease of anatomical entity DOID:7 0 0.026
central nervous system disease DOID:331 0 0.012
cardiovascular system disease DOID:1287 0 0.011