Mus musculus

0 known processes

Hif1an

hypoxia-inducible factor 1, alpha subunit inhibitor

(Aliases: 2310046M24Rik,A830014H24Rik,FIH1)

Hif1an biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 103 0.139
mitochondrion degradation GO:0000422 3 0.061
cellular response to dna damage stimulus GO:0006974 207 0.060
apoptotic signaling pathway GO:0097190 306 0.059
amine metabolic process GO:0009308 45 0.055
regulation of cellular ketone metabolic process GO:0010565 66 0.054
reactive oxygen species metabolic process GO:0072593 84 0.052
cellular ketone metabolic process GO:0042180 84 0.047
regulation of cellular amino acid metabolic process GO:0006521 5 0.047
cellular amine metabolic process GO:0044106 44 0.046
cell type specific apoptotic process GO:0097285 268 0.045
regulation of reactive oxygen species metabolic process GO:2000377 40 0.045
regulation of cellular amine metabolic process GO:0033238 20 0.045
regulation of cellular catabolic process GO:0031329 242 0.044
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.043
response to oxygen radical GO:0000305 16 0.043
regulation of apoptotic signaling pathway GO:2001233 197 0.042
response to radiation GO:0009314 165 0.042
regulation of membrane potential GO:0042391 192 0.040
reactive nitrogen species metabolic process GO:2001057 0 0.039
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.037
macromolecule catabolic process GO:0009057 281 0.036
mitochondrion organization GO:0007005 134 0.036
positive regulation of cellular amine metabolic process GO:0033240 5 0.036
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.036
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.036
regulation of neuron apoptotic process GO:0043523 122 0.035
regulation of cellular response to stress GO:0080135 159 0.035
peptidyl amino acid modification GO:0018193 336 0.034
Human
sulfur compound metabolic process GO:0006790 100 0.034
regulation of neuron death GO:1901214 134 0.034
negative regulation of cell proliferation GO:0008285 296 0.034
reactive oxygen species biosynthetic process GO:1903409 8 0.034
gland development GO:0048732 330 0.032
intrinsic apoptotic signaling pathway GO:0097193 132 0.031
response to oxidative stress GO:0006979 123 0.030
cellular response to superoxide GO:0071451 14 0.030
protein modification by small protein conjugation GO:0032446 187 0.030
regulation of organelle organization GO:0033043 289 0.029
neuron death GO:0070997 154 0.029
protein modification by small protein conjugation or removal GO:0070647 207 0.029
release of cytochrome c from mitochondria GO:0001836 23 0.029
removal of superoxide radicals GO:0019430 12 0.028
negative regulation of intracellular signal transduction GO:1902532 167 0.027
muscle tissue development GO:0060537 308 0.027
Human
fat cell differentiation GO:0045444 160 0.027
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.027
apoptotic mitochondrial changes GO:0008637 48 0.027
cellular response to oxidative stress GO:0034599 76 0.027
cytoplasmic transport GO:0016482 234 0.026
regulation of blood pressure GO:0008217 93 0.026
regulation of anatomical structure size GO:0090066 178 0.026
protein ubiquitination GO:0016567 171 0.026
locomotory behavior GO:0007626 195 0.026
negative regulation of apoptotic signaling pathway GO:2001234 104 0.025
protein catabolic process GO:0030163 221 0.025
positive regulation of protein modification process GO:0031401 299 0.025
blood circulation GO:0008015 195 0.025
negative regulation of protein metabolic process GO:0051248 282 0.025
neuron apoptotic process GO:0051402 142 0.025
heart morphogenesis GO:0003007 178 0.025
response to hyperoxia GO:0055093 2 0.025
negative regulation of cellular protein metabolic process GO:0032269 247 0.024
dna metabolic process GO:0006259 303 0.024
iron ion homeostasis GO:0055072 36 0.024
leukocyte differentiation GO:0002521 342 0.024
cation homeostasis GO:0055080 212 0.024
male gamete generation GO:0048232 285 0.024
cellular lipid metabolic process GO:0044255 323 0.023
response to oxygen levels GO:0070482 62 0.023
Human
negative regulation of cellular component organization GO:0051129 194 0.023
microtubule based process GO:0007017 236 0.023
cation transport GO:0006812 399 0.023
regulation of cell activation GO:0050865 289 0.023
intracellular protein transport GO:0006886 204 0.023
negative regulation of neuron death GO:1901215 98 0.023
negative regulation of molecular function GO:0044092 258 0.023
regulation of cell cycle GO:0051726 281 0.023
response to inorganic substance GO:0010035 96 0.022
carbohydrate metabolic process GO:0005975 230 0.022
nitrogen compound transport GO:0071705 271 0.022
detection of stimulus GO:0051606 84 0.022
circulatory system process GO:0003013 197 0.021
transmembrane transport GO:0055085 412 0.021
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 4 0.021
nucleoside phosphate metabolic process GO:0006753 338 0.021
negative regulation of neuron apoptotic process GO:0043524 92 0.021
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.021
organelle assembly GO:0070925 177 0.021
glutathione metabolic process GO:0006749 16 0.021
positive regulation of cell death GO:0010942 224 0.020
posttranscriptional regulation of gene expression GO:0010608 155 0.020
oocyte axis specification GO:0007309 2 0.020
cellular response to oxygen radical GO:0071450 14 0.020
regulation of protein localization GO:0032880 231 0.020
organonitrogen compound biosynthetic process GO:1901566 192 0.020
autophagy GO:0006914 45 0.020
myeloid cell differentiation GO:0030099 233 0.020
purine containing compound metabolic process GO:0072521 311 0.020
nucleobase containing small molecule metabolic process GO:0055086 352 0.020
oxidation reduction process GO:0055114 342 0.020
Human
camera type eye development GO:0043010 266 0.020
muscle cell differentiation GO:0042692 261 0.020
Human
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.019
mapk cascade GO:0000165 281 0.019
metal ion homeostasis GO:0055065 189 0.019
cellular protein catabolic process GO:0044257 155 0.019
pigmentation GO:0043473 71 0.019
immune effector process GO:0002252 321 0.019
superoxide metabolic process GO:0006801 27 0.019
homeostasis of number of cells GO:0048872 210 0.019
sensory organ morphogenesis GO:0090596 242 0.019
actin cytoskeleton organization GO:0030036 220 0.019
cell adhesion GO:0007155 329 0.018
peptide metabolic process GO:0006518 46 0.018
positive regulation of programmed cell death GO:0043068 218 0.018
chromatin organization GO:0006325 206 0.018
striated muscle tissue development GO:0014706 293 0.018
Human
negative regulation of cellular amine metabolic process GO:0033239 1 0.018
response to reactive oxygen species GO:0000302 56 0.018
regulation of lymphocyte activation GO:0051249 240 0.018
ras protein signal transduction GO:0007265 77 0.018
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.018
lipid biosynthetic process GO:0008610 179 0.018
small gtpase mediated signal transduction GO:0007264 97 0.018
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.018
modification dependent protein catabolic process GO:0019941 133 0.018
modification dependent macromolecule catabolic process GO:0043632 133 0.018
cytokine production GO:0001816 319 0.018
cellular macromolecule catabolic process GO:0044265 206 0.018
organelle localization GO:0051640 179 0.018
cellular component assembly involved in morphogenesis GO:0010927 139 0.017
wnt signaling pathway GO:0016055 188 0.017
response to increased oxygen levels GO:0036296 2 0.017
regulation of cytokine production GO:0001817 266 0.017
aromatic compound catabolic process GO:0019439 286 0.017
ribose phosphate metabolic process GO:0019693 291 0.017
compound eye development GO:0048749 1 0.017
cation transmembrane transport GO:0098655 266 0.017
positive regulation of protein phosphorylation GO:0001934 242 0.017
cellular homeostasis GO:0019725 240 0.017
ribonucleotide metabolic process GO:0009259 291 0.017
regulation of hydrolase activity GO:0051336 246 0.017
developmental pigmentation GO:0048066 40 0.017
maintenance of location GO:0051235 89 0.017
stem cell differentiation GO:0048863 268 0.017
transition metal ion homeostasis GO:0055076 54 0.017
negative regulation of phosphorus metabolic process GO:0010563 184 0.017
positive regulation of apoptotic process GO:0043065 217 0.017
positive regulation of cell development GO:0010720 237 0.017
generation of precursor metabolites and energy GO:0006091 103 0.017
membrane organization GO:0061024 245 0.017
negative regulation of protein modification process GO:0031400 163 0.017
lymphocyte differentiation GO:0030098 242 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.016
regulation of mapk cascade GO:0043408 248 0.016
sensory perception GO:0007600 245 0.016
regulation of neuron differentiation GO:0045664 281 0.016
ossification GO:0001503 216 0.016
regulation of transferase activity GO:0051338 263 0.016
purine nucleotide metabolic process GO:0006163 302 0.016
response to organonitrogen compound GO:0010243 246 0.016
carbohydrate derivative biosynthetic process GO:1901137 183 0.016
hepaticobiliary system development GO:0061008 67 0.016
purine ribonucleoside metabolic process GO:0046128 241 0.016
microtubule cytoskeleton organization GO:0000226 157 0.016
organic cyclic compound catabolic process GO:1901361 295 0.016
energy derivation by oxidation of organic compounds GO:0015980 77 0.016
skeletal system development GO:0001501 356 0.016
nucleocytoplasmic transport GO:0006913 139 0.016
negative regulation of phosphate metabolic process GO:0045936 184 0.016
blood vessel morphogenesis GO:0048514 285 0.016
regulation of proteolysis GO:0030162 164 0.016
pigment cell differentiation GO:0050931 27 0.016
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.016
cellular response to organonitrogen compound GO:0071417 145 0.016
endocytosis GO:0006897 168 0.016
inorganic cation transmembrane transport GO:0098662 207 0.015
cellular nitrogen compound catabolic process GO:0044270 280 0.015
regulation of fat cell differentiation GO:0045598 81 0.015
cell growth GO:0016049 130 0.015
liver development GO:0001889 66 0.015
regulation of establishment of protein localization GO:0070201 181 0.015
regulation of protein kinase activity GO:0045859 232 0.015
t cell activation GO:0042110 289 0.015
rho protein signal transduction GO:0007266 32 0.015
oocyte construction GO:0007308 2 0.015
endomembrane system organization GO:0010256 147 0.015
protein oligomerization GO:0051259 67 0.015
regulation of cellular component biogenesis GO:0044087 181 0.015
regulation of secretion GO:0051046 274 0.015
purine nucleoside triphosphate catabolic process GO:0009146 203 0.015
negative regulation of phosphorylation GO:0042326 166 0.015
ubiquitin dependent protein catabolic process GO:0006511 129 0.015
nucleoside triphosphate metabolic process GO:0009141 230 0.015
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 34 0.015
regulation of cellular response to oxidative stress GO:1900407 19 0.015
axonogenesis GO:0007409 274 0.015
protein processing GO:0016485 163 0.015
inflammatory response GO:0006954 244 0.015
negative regulation of protein phosphorylation GO:0001933 126 0.015
placenta development GO:0001890 140 0.014
synaptic transmission GO:0007268 329 0.014
regulation of kinase activity GO:0043549 249 0.014
germ cell development GO:0007281 185 0.014
ribonucleoside metabolic process GO:0009119 245 0.014
dephosphorylation GO:0016311 129 0.014
regulation of t cell activation GO:0050863 170 0.014
response to ionizing radiation GO:0010212 42 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.014
digestive tract development GO:0048565 190 0.014
nuclear transport GO:0051169 139 0.014
regulation of systemic arterial blood pressure GO:0003073 61 0.014
regulation of mitochondrial membrane potential GO:0051881 17 0.014
developmental maturation GO:0021700 193 0.014
chemotaxis GO:0006935 247 0.014
negative regulation of immune system process GO:0002683 209 0.014
spermatogenesis GO:0007283 284 0.014
transmission of nerve impulse GO:0019226 76 0.014
response to lipopolysaccharide GO:0032496 128 0.014
protein targeting GO:0006605 143 0.014
covalent chromatin modification GO:0016569 163 0.014
organophosphate catabolic process GO:0046434 232 0.014
engulfment of apoptotic cell GO:0043652 3 0.014
purine ribonucleotide metabolic process GO:0009150 290 0.014
respiratory system development GO:0060541 190 0.014
multicellular organismal signaling GO:0035637 91 0.014
ribonucleoside triphosphate metabolic process GO:0009199 220 0.014
cellular amide metabolic process GO:0043603 58 0.014
embryonic organ morphogenesis GO:0048562 276 0.014
purine nucleoside metabolic process GO:0042278 241 0.013
divalent inorganic cation transport GO:0072511 178 0.013
monocarboxylic acid metabolic process GO:0032787 191 0.013
regulation of cytoskeleton organization GO:0051493 122 0.013
organonitrogen compound catabolic process GO:1901565 264 0.013
response to insulin GO:0032868 100 0.013
retrograde transport endosome to golgi GO:0042147 2 0.013
regulation of cellular component size GO:0032535 121 0.013
anatomical structure homeostasis GO:0060249 145 0.013
skeletal muscle organ development GO:0060538 163 0.013
Human
glycosyl compound metabolic process GO:1901657 246 0.013
cellular response to hormone stimulus GO:0032870 150 0.013
regulation of protein catabolic process GO:0042176 108 0.013
cellular protein complex assembly GO:0043623 116 0.013
urogenital system development GO:0001655 261 0.013
negative regulation of fat cell differentiation GO:0045599 36 0.013
divalent metal ion transport GO:0070838 172 0.013
regulation of leukocyte differentiation GO:1902105 159 0.013
purine nucleoside triphosphate metabolic process GO:0009144 226 0.013
cellular carbohydrate metabolic process GO:0044262 119 0.013
cellular response to cytokine stimulus GO:0071345 189 0.013
g protein coupled receptor signaling pathway GO:0007186 243 0.013
regulation of secretion by cell GO:1903530 249 0.013
regulation of autophagy GO:0010506 30 0.013
sequestering of calcium ion GO:0051208 18 0.013
regionalization GO:0003002 337 0.013
histone modification GO:0016570 159 0.013
protein import GO:0017038 101 0.013
chromatin modification GO:0016568 187 0.013
action potential GO:0001508 78 0.013
digestive system development GO:0055123 200 0.013
regulation of system process GO:0044057 200 0.013
heterocycle catabolic process GO:0046700 280 0.013
nucleoside phosphate catabolic process GO:1901292 222 0.013
gas homeostasis GO:0033483 3 0.013
ion transmembrane transport GO:0034220 361 0.013
regulation of cell cycle process GO:0010564 160 0.012
regulation of ion transport GO:0043269 215 0.012
regulation of cell adhesion GO:0030155 154 0.012
b cell activation GO:0042113 161 0.012
spermatid differentiation GO:0048515 115 0.012
response to molecule of bacterial origin GO:0002237 143 0.012
regulation of protein transport GO:0051223 163 0.012
regulation of hormone levels GO:0010817 211 0.012
protein localization to organelle GO:0033365 185 0.012
proteasomal protein catabolic process GO:0010498 98 0.012
organelle fission GO:0048285 170 0.012
positive regulation of cellular catabolic process GO:0031331 148 0.012
regulation of vesicle mediated transport GO:0060627 139 0.012
regulation of intracellular transport GO:0032386 159 0.012
mitochondrion distribution GO:0048311 4 0.012
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 19 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.012
cellular chemical homeostasis GO:0055082 215 0.012
response to light stimulus GO:0009416 135 0.012
nucleotide metabolic process GO:0009117 332 0.012
carbohydrate derivative catabolic process GO:1901136 231 0.012
protein homooligomerization GO:0051260 43 0.012
lymphocyte proliferation GO:0046651 164 0.012
respiratory tube development GO:0030323 167 0.012
regulation of blood vessel size GO:0050880 56 0.012
protein maturation GO:0051604 176 0.012
defense response to other organism GO:0098542 197 0.012
mitotic cell cycle GO:0000278 195 0.012
epithelial cell development GO:0002064 159 0.012
regulation of cell growth GO:0001558 91 0.012
regulation of cell projection organization GO:0031344 206 0.012
age dependent general metabolic decline GO:0007571 3 0.012
multicellular organism growth GO:0035264 161 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
ribonucleoside catabolic process GO:0042454 206 0.012
neuronal action potential GO:0019228 54 0.012
muscle system process GO:0003012 141 0.012
nucleoside triphosphate catabolic process GO:0009143 205 0.012
innate immune response GO:0045087 157 0.012
organic anion transport GO:0015711 137 0.012
inorganic ion transmembrane transport GO:0098660 234 0.012
age dependent response to oxidative stress GO:0001306 3 0.012
organic hydroxy compound metabolic process GO:1901615 203 0.012
stem cell development GO:0048864 219 0.012
response to growth factor GO:0070848 198 0.011
regulation of defense response GO:0031347 233 0.011
carboxylic acid biosynthetic process GO:0046394 86 0.011
cellular response to lipid GO:0071396 145 0.011
glucose homeostasis GO:0042593 128 0.011
regulation of transmembrane transport GO:0034762 128 0.011
sequestering of metal ion GO:0051238 19 0.011
developmental growth involved in morphogenesis GO:0060560 138 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.011
regulation of mitotic cell cycle GO:0007346 126 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.011
organic acid biosynthetic process GO:0016053 86 0.011
methylation GO:0032259 134 0.011
purine containing compound catabolic process GO:0072523 213 0.011
response to peptide hormone GO:0043434 127 0.011
positive regulation of organelle organization GO:0010638 128 0.011
paracrine signaling GO:0038001 1 0.011
renal system development GO:0072001 225 0.011
canonical wnt signaling pathway GO:0060070 130 0.011
negative regulation of cell cycle GO:0045786 123 0.011
cellular response to peptide hormone stimulus GO:0071375 92 0.011
negative regulation of nervous system development GO:0051961 156 0.011
regulation of response to wounding GO:1903034 189 0.011
myosin filament organization GO:0031033 3 0.011
myeloid cell homeostasis GO:0002262 114 0.011
myosin filament assembly GO:0031034 2 0.011
calcium ion transport GO:0006816 159 0.011
positive regulation of nervous system development GO:0051962 221 0.011
regulation of cell migration GO:0030334 219 0.011
carbohydrate homeostasis GO:0033500 128 0.011
regulation of homeostatic process GO:0032844 182 0.011
regulation of multi organism process GO:0043900 111 0.011
leukocyte proliferation GO:0070661 172 0.011
vascular process in circulatory system GO:0003018 62 0.011
lateral inhibition GO:0046331 1 0.011
mitotic cell cycle process GO:1903047 159 0.011
regulation of tube size GO:0035150 57 0.011
muscle contraction GO:0006936 101 0.011
ear development GO:0043583 200 0.011
response to extracellular stimulus GO:0009991 127 0.011
regulation of response to oxidative stress GO:1902882 19 0.011
dna repair GO:0006281 107 0.011
striated muscle myosin thick filament assembly GO:0071688 1 0.011
gonad development GO:0008406 141 0.011
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.011
single organism cell adhesion GO:0098602 156 0.010
cellular response to growth factor stimulus GO:0071363 197 0.010
purine nucleoside catabolic process GO:0006152 205 0.010
cell substrate adhesion GO:0031589 130 0.010
regulation of striated muscle cell differentiation GO:0051153 81 0.010
Human
organophosphate biosynthetic process GO:0090407 122 0.010
intracellular mrna localization GO:0008298 4 0.010
purine ribonucleoside catabolic process GO:0046130 205 0.010
striated muscle cell development GO:0055002 125 0.010
Human
regulation of cell motility GO:2000145 236 0.010
nuclear import GO:0051170 95 0.010
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.010
myotube differentiation GO:0014902 105 0.010
Human
cell maturation GO:0048469 127 0.010
angiogenesis GO:0001525 201 0.010
alcohol metabolic process GO:0006066 116 0.010
cellular response to peptide GO:1901653 92 0.010
positive regulation of hydrolase activity GO:0051345 148 0.010
negative regulation of organelle organization GO:0010639 90 0.010
interleukin 8 production GO:0032637 4 0.010
glycoprotein metabolic process GO:0009100 116 0.010
ribonucleotide catabolic process GO:0009261 208 0.010
myeloid leukocyte differentiation GO:0002573 119 0.010
peptidyl lysine modification GO:0018205 77 0.010
forebrain development GO:0030900 302 0.010
rna processing GO:0006396 105 0.010
regulation of wnt signaling pathway GO:0030111 123 0.010
rhythmic process GO:0048511 174 0.010
pharynx development GO:0060465 1 0.010
negative regulation of response to oxidative stress GO:1902883 10 0.010
fibroblast proliferation GO:0048144 35 0.010
epithelial tube morphogenesis GO:0060562 303 0.010
vasodilation GO:0042311 28 0.010
regulation of chromosome organization GO:0033044 83 0.010
leukocyte mediated immunity GO:0002443 174 0.010
cellular response to insulin stimulus GO:0032869 78 0.010
cytokinetic process GO:0032506 2 0.010

Hif1an disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.023
nervous system disease DOID:863 0 0.023
immune system disease DOID:2914 0 0.020
hematopoietic system disease DOID:74 0 0.014
musculoskeletal system disease DOID:17 0 0.014
disease of metabolism DOID:0014667 0 0.012
central nervous system disease DOID:331 0 0.012
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
organ system cancer DOID:0050686 0 0.012
connective tissue disease DOID:65 0 0.011
sensory system disease DOID:0050155 0 0.011