Mus musculus

82 known processes

Hipk1

homeodomain interacting protein kinase 1

(Aliases: 1110062K04Rik,Myak)

Hipk1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of nik nf kappab signaling GO:1901223 2 0.958
epidermal growth factor receptor signaling pathway via i kappab kinase nf kappab cascade GO:0038168 1 0.944
protein modification by small protein conjugation or removal GO:0070647 207 0.699
protein modification by small protein conjugation GO:0032446 187 0.535
epidermal growth factor receptor signaling pathway via positive regulation of nf kappab transcription factor activity GO:0038167 1 0.358
protein ubiquitination GO:0016567 171 0.354
negative regulation of intracellular signal transduction GO:1902532 167 0.219
Mouse
regulation of transferase activity GO:0051338 263 0.214
Mouse
ras protein signal transduction GO:0007265 77 0.198
regulation of protein kinase activity GO:0045859 232 0.176
Mouse
negative regulation of cell cycle arrest GO:0071157 1 0.167
osteoclast differentiation GO:0030316 62 0.155
modification dependent macromolecule catabolic process GO:0043632 133 0.150
engulfment of apoptotic cell GO:0043652 3 0.141
positive regulation of protein ubiquitination GO:0031398 27 0.135
small gtpase mediated signal transduction GO:0007264 97 0.130
negative regulation of cellular protein metabolic process GO:0032269 247 0.127
Mouse
regulation of cellular response to stress GO:0080135 159 0.123
Mouse
homeostasis of number of cells GO:0048872 210 0.123
regulation of protein localization GO:0032880 231 0.122
signal transduction involved in dna integrity checkpoint GO:0072401 3 0.118
cellular macromolecule catabolic process GO:0044265 206 0.115
negative regulation of phosphorus metabolic process GO:0010563 184 0.112
Mouse
protein localization to organelle GO:0033365 185 0.111
bone remodeling GO:0046849 53 0.108
negative regulation of phosphorylation GO:0042326 166 0.106
Mouse
peptidyl serine modification GO:0018209 83 0.104
Mouse
leukocyte differentiation GO:0002521 342 0.103
signal transduction involved in mitotic dna damage checkpoint GO:1902402 3 0.100
cellular response to dna damage stimulus GO:0006974 207 0.097
negative regulation of cell proliferation GO:0008285 296 0.097
protein processing GO:0016485 163 0.096
organic cyclic compound catabolic process GO:1901361 295 0.095
regulation of osteoclast differentiation GO:0045670 36 0.094
peptidyl serine phosphorylation GO:0018105 74 0.091
Mouse
regulation of leukocyte differentiation GO:1902105 159 0.088
regulation of cell cycle GO:0051726 281 0.086
positive regulation of protein modification by small protein conjugation or removal GO:1903322 30 0.084
regulation of protein ubiquitination GO:0031396 52 0.083
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.081
modification dependent protein catabolic process GO:0019941 133 0.080
cellular protein catabolic process GO:0044257 155 0.079
cell type specific apoptotic process GO:0097285 268 0.077
Human Mouse
aromatic compound catabolic process GO:0019439 286 0.075
macromolecule catabolic process GO:0009057 281 0.075
protein maturation GO:0051604 176 0.074
posttranscriptional regulation of gene expression GO:0010608 155 0.073
Fly
positive regulation of protein phosphorylation GO:0001934 242 0.071
Mouse
protein localization to nucleus GO:0034504 121 0.070
ubiquitin dependent protein catabolic process GO:0006511 129 0.068
positive regulation of protein modification process GO:0031401 299 0.068
Mouse
regulation of protein maturation GO:1903317 96 0.068
regionalization GO:0003002 337 0.067
skeletal system development GO:0001501 356 0.067
regulation of cellular catabolic process GO:0031329 242 0.067
regulation of cellular ketone metabolic process GO:0010565 66 0.066
amine metabolic process GO:0009308 45 0.064
cellular response to peptide GO:1901653 92 0.064
protein autophosphorylation GO:0046777 61 0.062
Mouse
negative regulation of transferase activity GO:0051348 85 0.062
Mouse
traversing start control point of mitotic cell cycle GO:0007089 2 0.059
protein catabolic process GO:0030163 221 0.058
positive regulation of cellular catabolic process GO:0031331 148 0.057
regulation of defense response GO:0031347 233 0.057
intracellular signal transduction involved in g1 dna damage checkpoint GO:1902400 3 0.057
carbohydrate metabolic process GO:0005975 230 0.055
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.055
insulin receptor signaling pathway GO:0008286 49 0.054
regulation of protein stability GO:0031647 52 0.052
Fly
negative regulation of protein phosphorylation GO:0001933 126 0.052
Mouse
negative regulation of kinase activity GO:0033673 81 0.052
Mouse
regulation of system process GO:0044057 200 0.051
response to growth factor GO:0070848 198 0.051
Mouse
regulation of mapk cascade GO:0043408 248 0.051
Mouse
proteasomal protein catabolic process GO:0010498 98 0.051
purine ribonucleotide metabolic process GO:0009150 290 0.051
signal transduction involved in mitotic dna integrity checkpoint GO:1902403 3 0.051
myeloid cell differentiation GO:0030099 233 0.051
signal transduction by p53 class mediator GO:0072331 51 0.050
cognition GO:0050890 149 0.049
germ cell development GO:0007281 185 0.049
regulation of map kinase activity GO:0043405 120 0.048
Mouse
cellular lipid metabolic process GO:0044255 323 0.048
regulation of myeloid cell differentiation GO:0045637 96 0.048
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.048
cellular response to growth factor stimulus GO:0071363 197 0.048
Mouse
membrane organization GO:0061024 245 0.048
regulation of insulin receptor signaling pathway GO:0046626 21 0.047
cellular response to organonitrogen compound GO:0071417 145 0.047
cytokine production GO:0001816 319 0.047
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.046
Mouse
peptidyl amino acid modification GO:0018193 336 0.046
Mouse
lipid biosynthetic process GO:0008610 179 0.045
regulation of cellular component biogenesis GO:0044087 181 0.044
negative regulation of proteolysis GO:0045861 74 0.043
positive regulation of apoptotic process GO:0043065 217 0.043
cellular nitrogen compound catabolic process GO:0044270 280 0.042
monosaccharide metabolic process GO:0005996 106 0.042
regulation of hydrolase activity GO:0051336 246 0.042
regulation of cellular component size GO:0032535 121 0.041
signal transduction involved in cell cycle checkpoint GO:0072395 3 0.041
positive regulation of nucleotide metabolic process GO:0045981 114 0.041
purine nucleotide metabolic process GO:0006163 302 0.040
signal transduction involved in mitotic cell cycle checkpoint GO:0072413 3 0.040
negative regulation of neuron apoptotic process GO:0043524 92 0.039
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.039
cell cycle g1 s phase transition GO:0044843 57 0.038
organophosphate catabolic process GO:0046434 232 0.038
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.037
regulation of apoptotic signaling pathway GO:2001233 197 0.037
mitotic g1 dna damage checkpoint GO:0031571 4 0.036
negative regulation of cellular component organization GO:0051129 194 0.036
dna metabolic process GO:0006259 303 0.036
regulation of cell size GO:0008361 72 0.036
cellular homeostasis GO:0019725 240 0.035
regulation of cell migration GO:0030334 219 0.035
action potential GO:0001508 78 0.035
regulation of nucleotide metabolic process GO:0006140 169 0.035
rho protein signal transduction GO:0007266 32 0.035
myeloid leukocyte differentiation GO:0002573 119 0.035
negative regulation of dna damage response signal transduction by p53 class mediator GO:0043518 5 0.035
cellular response to peptide hormone stimulus GO:0071375 92 0.035
ribose phosphate metabolic process GO:0019693 291 0.035
regulation of protein localization to nucleus GO:1900180 60 0.034
cellular response to hormone stimulus GO:0032870 150 0.033
negative regulation of molecular function GO:0044092 258 0.033
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.033
positive regulation of kinase activity GO:0033674 155 0.033
regulation of inflammatory response GO:0050727 147 0.033
dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 3 0.033
positive regulation of cellular amine metabolic process GO:0033240 5 0.032
regulation of neuron death GO:1901214 134 0.032
Mouse
regulation of protein catabolic process GO:0042176 108 0.032
tissue remodeling GO:0048771 102 0.032
stress activated protein kinase signaling cascade GO:0031098 81 0.032
Mouse
response to endoplasmic reticulum stress GO:0034976 53 0.032
cellular amino acid metabolic process GO:0006520 103 0.032
negative regulation of cellular amine metabolic process GO:0033239 1 0.032
cellular response to extracellular stimulus GO:0031668 81 0.031
regulation of cellular amino acid metabolic process GO:0006521 5 0.031
ossification GO:0001503 216 0.031
regulation of response to wounding GO:1903034 189 0.031
angiogenesis GO:0001525 201 0.031
cellular amine metabolic process GO:0044106 44 0.030
dephosphorylation GO:0016311 129 0.030
nucleoside phosphate catabolic process GO:1901292 222 0.030
intrinsic apoptotic signaling pathway GO:0097193 132 0.030
neuron death GO:0070997 154 0.030
Mouse
ion transmembrane transport GO:0034220 361 0.030
organelle localization GO:0051640 179 0.029
regulation of protein processing GO:0070613 96 0.029
nucleobase containing small molecule metabolic process GO:0055086 352 0.029
t cell activation GO:0042110 289 0.029
male gamete generation GO:0048232 285 0.029
endomembrane system organization GO:0010256 147 0.029
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.028
positive regulation of cell death GO:0010942 224 0.028
regulation of intracellular transport GO:0032386 159 0.028
regulation of cell cycle process GO:0010564 160 0.028
actin filament organization GO:0007015 113 0.027
regulation of cell activation GO:0050865 289 0.027
ribonucleoside triphosphate catabolic process GO:0009203 199 0.027
cellular response to nutrient levels GO:0031669 64 0.027
cellular ketone metabolic process GO:0042180 84 0.027
inflammatory response GO:0006954 244 0.026
ribonucleoside catabolic process GO:0042454 206 0.026
sensory organ morphogenesis GO:0090596 242 0.026
cellular carbohydrate metabolic process GO:0044262 119 0.026
ribonucleoside metabolic process GO:0009119 245 0.026
regulation of response to drug GO:2001023 2 0.026
blood vessel morphogenesis GO:0048514 285 0.026
regulation of reactive oxygen species metabolic process GO:2000377 40 0.026
negative regulation of protein metabolic process GO:0051248 282 0.026
Mouse
purine nucleotide catabolic process GO:0006195 211 0.026
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.026
regulation of cellular response to growth factor stimulus GO:0090287 82 0.026
cation transmembrane transport GO:0098655 266 0.025
lipid transport GO:0006869 98 0.025
glycerophospholipid metabolic process GO:0006650 71 0.025
chemotaxis GO:0006935 247 0.025
response to peptide GO:1901652 136 0.025
nucleotide catabolic process GO:0009166 217 0.025
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.025
Mouse
regulation of secretion GO:0051046 274 0.025
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 35 0.025
mitotic cell cycle GO:0000278 195 0.024
skeletal muscle organ development GO:0060538 163 0.024
negative regulation of mapk cascade GO:0043409 65 0.024
Mouse
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.024
Mouse
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.024
regulation of purine nucleotide catabolic process GO:0033121 122 0.024
transmembrane transport GO:0055085 412 0.024
nucleoside catabolic process GO:0009164 206 0.024
positive regulation of cell activation GO:0050867 158 0.024
mapk cascade GO:0000165 281 0.024
Mouse
regulation of cell projection organization GO:0031344 206 0.024
response to oxidative stress GO:0006979 123 0.024
b cell activation GO:0042113 161 0.023
neuronal action potential GO:0019228 54 0.023
cellular response to insulin stimulus GO:0032869 78 0.023
dna damage response signal transduction by p53 class mediator GO:0030330 19 0.023
regulation of ossification GO:0030278 112 0.023
organic hydroxy compound metabolic process GO:1901615 203 0.023
negative regulation of response to wounding GO:1903035 77 0.023
inorganic ion transmembrane transport GO:0098660 234 0.023
regulation of ion transport GO:0043269 215 0.023
nucleoside metabolic process GO:0009116 246 0.023
cytokine mediated signaling pathway GO:0019221 115 0.023
Human
negative regulation of cell cycle process GO:0010948 69 0.023
response to extracellular stimulus GO:0009991 127 0.023
regulation of lymphocyte activation GO:0051249 240 0.023
regulation of engulfment of apoptotic cell GO:1901074 2 0.023
ribonucleoside triphosphate metabolic process GO:0009199 220 0.023
regulation of anatomical structure size GO:0090066 178 0.023
glial cell apoptotic process GO:0034349 3 0.022
regulation of cytokine production GO:0001817 266 0.022
regulation of cytoskeleton organization GO:0051493 122 0.022
g protein coupled receptor signaling pathway GO:0007186 243 0.022
regulation of mitotic cell cycle GO:0007346 126 0.022
gtp metabolic process GO:0046039 144 0.022
regulation of mitotic cell cycle phase transition GO:1901990 73 0.022
blood circulation GO:0008015 195 0.022
purine ribonucleotide catabolic process GO:0009154 208 0.022
gtp catabolic process GO:0006184 143 0.022
rhythmic process GO:0048511 174 0.022
response to nutrient levels GO:0031667 109 0.022
regulation of gtp catabolic process GO:0033124 113 0.022
regulation of response to dna damage stimulus GO:2001020 34 0.022
synaptic transmission GO:0007268 329 0.022
spermatogenesis GO:0007283 284 0.022
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.022
Mouse
photoreceptor cell morphogenesis GO:0008594 3 0.021
negative regulation of map kinase activity GO:0043407 34 0.021
Mouse
erbb signaling pathway GO:0038127 32 0.021
cellular response to decreased oxygen levels GO:0036294 18 0.021
myotube differentiation GO:0014902 105 0.021
regulation of nucleotide catabolic process GO:0030811 122 0.021
response to organonitrogen compound GO:0010243 246 0.021
phosphatidylinositol metabolic process GO:0046488 45 0.021
regulation of jun kinase activity GO:0043506 40 0.021
Mouse
negative regulation of cellular catabolic process GO:0031330 47 0.021
phosphorylated carbohydrate dephosphorylation GO:0046838 4 0.021
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.021
response to oxygen levels GO:0070482 62 0.021
mitotic cell cycle process GO:1903047 159 0.020
peptidyl lysine modification GO:0018205 77 0.020
positive regulation of growth GO:0045927 104 0.020
regulation of membrane potential GO:0042391 192 0.020
negative regulation of phosphate metabolic process GO:0045936 184 0.020
Mouse
alcohol metabolic process GO:0006066 116 0.020
oxidation reduction process GO:0055114 342 0.020
negative regulation of protein maturation GO:1903318 79 0.020
nucleoside phosphate metabolic process GO:0006753 338 0.020
lipid homeostasis GO:0055088 63 0.020
muscle system process GO:0003012 141 0.020
cell growth GO:0016049 130 0.020
cell activation involved in immune response GO:0002263 126 0.020
multicellular organismal homeostasis GO:0048871 164 0.019
positive regulation of nucleotide catabolic process GO:0030813 88 0.019
anion transport GO:0006820 177 0.019
negative regulation of phagocytosis GO:0050765 4 0.019
adult behavior GO:0030534 135 0.019
Mouse
organophosphate biosynthetic process GO:0090407 122 0.019
intracellular protein transport GO:0006886 204 0.019
cellular response to external stimulus GO:0071496 88 0.019
vacuole organization GO:0007033 38 0.019
sphingolipid metabolic process GO:0006665 45 0.019
regulation of proteolysis GO:0030162 164 0.019
axonogenesis GO:0007409 274 0.019
positive regulation of nucleoside metabolic process GO:0045979 91 0.019
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 23 0.019
glycerolipid biosynthetic process GO:0045017 50 0.019
plasma membrane long chain fatty acid transport GO:0015911 1 0.019
purine containing compound metabolic process GO:0072521 311 0.019
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.019
organonitrogen compound biosynthetic process GO:1901566 192 0.019
muscle tissue development GO:0060537 308 0.019
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.019
establishment of organelle localization GO:0051656 122 0.018
anatomical structure homeostasis GO:0060249 145 0.018
response to light stimulus GO:0009416 135 0.018
spermatid differentiation GO:0048515 115 0.018
regulation of osteoblast differentiation GO:0045667 67 0.018
cellular response to starvation GO:0009267 57 0.018
nucleotide metabolic process GO:0009117 332 0.018
negative regulation of nervous system development GO:0051961 156 0.018
immune effector process GO:0002252 321 0.018
hormone metabolic process GO:0042445 86 0.018
exocytosis GO:0006887 121 0.018
reactive oxygen species metabolic process GO:0072593 84 0.018
reactive oxygen species biosynthetic process GO:1903409 8 0.018
protein kinase b signaling GO:0043491 74 0.018
apical constriction GO:0003383 4 0.018
anion transmembrane transport GO:0098656 71 0.018
heterocycle catabolic process GO:0046700 280 0.018
regulation of protein serine threonine kinase activity GO:0071900 157 0.018
Mouse
positive regulation of mapk cascade GO:0043410 170 0.018
response to insulin GO:0032868 100 0.018
glucose homeostasis GO:0042593 128 0.018
epidermal growth factor receptor signaling pathway GO:0007173 28 0.018
wound healing GO:0042060 157 0.018
dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator GO:0006978 2 0.018
phospholipid metabolic process GO:0006644 87 0.018
regulation of intracellular protein transport GO:0033157 82 0.017
photoreceptor cell development GO:0042461 40 0.017
cellular protein complex assembly GO:0043623 116 0.017
leukocyte proliferation GO:0070661 172 0.017
fibroblast migration GO:0010761 21 0.017
nitrogen compound transport GO:0071705 271 0.017
purine nucleoside metabolic process GO:0042278 241 0.017
inorganic cation transmembrane transport GO:0098662 207 0.017
carbohydrate homeostasis GO:0033500 128 0.017
purine containing compound catabolic process GO:0072523 213 0.017
regulation of cellular protein catabolic process GO:1903362 61 0.017
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.017
purine nucleoside triphosphate catabolic process GO:0009146 203 0.017
regulation of hormone levels GO:0010817 211 0.017
regulation of organelle organization GO:0033043 289 0.017
glycoprotein biosynthetic process GO:0009101 89 0.017
t cell differentiation in thymus GO:0033077 77 0.017
hormone secretion GO:0046879 128 0.017
leukocyte mediated immunity GO:0002443 174 0.017
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 25 0.017
regulation of proteasomal protein catabolic process GO:0061136 46 0.017
vesicle localization GO:0051648 86 0.017
cell adhesion GO:0007155 329 0.017
multi multicellular organism process GO:0044706 109 0.017
single organismal cell cell adhesion GO:0016337 131 0.017
hexose metabolic process GO:0019318 98 0.017
regulation of protein transport GO:0051223 163 0.016
regulation of actin cytoskeleton organization GO:0032956 84 0.016
female gamete generation GO:0007292 74 0.016
epithelial cell development GO:0002064 159 0.016
cellular response to oxygen levels GO:0071453 20 0.016
positive regulation of gtpase activity GO:0043547 85 0.016
single organism cell adhesion GO:0098602 156 0.016
cation transport GO:0006812 399 0.016
response to acid chemical GO:0001101 111 0.016
positive regulation of tor signaling GO:0032008 3 0.016
small molecule catabolic process GO:0044282 71 0.016
cell substrate adhesion GO:0031589 130 0.016
glycerolipid metabolic process GO:0046486 122 0.016
regulation of vesicle mediated transport GO:0060627 139 0.016
notch signaling pathway GO:0007219 71 0.016
Fly
response to monosaccharide GO:0034284 67 0.016
small molecule biosynthetic process GO:0044283 132 0.016
regulation of endopeptidase activity GO:0052548 89 0.016
monocarboxylic acid metabolic process GO:0032787 191 0.016
jnk cascade GO:0007254 72 0.016
Mouse
positive regulation of nervous system development GO:0051962 221 0.016
regulation of wnt signaling pathway GO:0030111 123 0.016
Fly
cellular response to x ray GO:0071481 2 0.016
protein polymerization GO:0051258 57 0.016
response to hypoxia GO:0001666 58 0.016
renal system development GO:0072001 225 0.016
positive regulation of cell motility GO:2000147 116 0.016
embryonic organ morphogenesis GO:0048562 276 0.016
regulation of myeloid leukocyte differentiation GO:0002761 58 0.016
organic anion transport GO:0015711 137 0.016
dendrite development GO:0016358 115 0.016
sulfur compound biosynthetic process GO:0044272 37 0.016
carbohydrate derivative biosynthetic process GO:1901137 183 0.016
striated muscle tissue development GO:0014706 293 0.016
placenta development GO:0001890 140 0.016
translational initiation GO:0006413 24 0.016
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.016
stem cell differentiation GO:0048863 268 0.015
erythrocyte differentiation GO:0030218 88 0.015
inositol phosphate catabolic process GO:0071545 4 0.015
microtubule cytoskeleton organization GO:0000226 157 0.015
regulation of cell cycle g1 s phase transition GO:1902806 35 0.015
regulation of kinase activity GO:0043549 249 0.015
Mouse
organic acid biosynthetic process GO:0016053 86 0.015
regulation of endocytosis GO:0030100 69 0.015
cell cycle arrest GO:0007050 37 0.015
muscle cell differentiation GO:0042692 261 0.015
positive regulation of cell cycle phase transition GO:1901989 17 0.015
regulation of translation GO:0006417 71 0.015
metal ion homeostasis GO:0055065 189 0.015
response to organic cyclic compound GO:0014070 198 0.015
endocytosis GO:0006897 168 0.015
cellular chemical homeostasis GO:0055082 215 0.015
nuclear division GO:0000280 158 0.015
lipid modification GO:0030258 65 0.015
glycoprotein metabolic process GO:0009100 116 0.015
carboxylic acid biosynthetic process GO:0046394 86 0.015
peptide secretion GO:0002790 114 0.015
locomotory behavior GO:0007626 195 0.015
Mouse
interleukin 8 production GO:0032637 4 0.015
regulation of body fluid levels GO:0050878 162 0.015
positive regulation of cell cycle GO:0045787 92 0.015
circulatory system process GO:0003013 197 0.015
sulfur compound metabolic process GO:0006790 100 0.015
mitotic cytokinesis GO:0000281 4 0.015
transmission of nerve impulse GO:0019226 76 0.015
negative regulation of apoptotic signaling pathway GO:2001234 104 0.015
response to starvation GO:0042594 65 0.015
regulation of lipid transport GO:0032368 36 0.015
regulation of leukocyte proliferation GO:0070663 121 0.014
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.014
regulation of cell cycle arrest GO:0071156 12 0.014
positive regulation of cellular protein catabolic process GO:1903364 34 0.014
cytoplasmic transport GO:0016482 234 0.014
organelle assembly GO:0070925 177 0.014
response to decreased oxygen levels GO:0036293 59 0.014
glycosyl compound catabolic process GO:1901658 206 0.014
fatty acid metabolic process GO:0006631 121 0.014
g0 to g1 transition GO:0045023 3 0.014
reactive nitrogen species metabolic process GO:2001057 0 0.014
regulation of hormone secretion GO:0046883 88 0.014
gland development GO:0048732 330 0.014
organonitrogen compound catabolic process GO:1901565 264 0.014
g1 s transition of mitotic cell cycle GO:0000082 57 0.014
axon ensheathment GO:0008366 76 0.014
oocyte construction GO:0007308 2 0.014
response to reactive oxygen species GO:0000302 56 0.014
cellular response to carbohydrate stimulus GO:0071322 50 0.014
blastocyst development GO:0001824 80 0.014
rna processing GO:0006396 105 0.014
maintenance of location GO:0051235 89 0.014
retina development in camera type eye GO:0060041 119 0.014
adaptive immune response GO:0002250 155 0.014
purine ribonucleoside catabolic process GO:0046130 205 0.014
innate immune response GO:0045087 157 0.014
immune response regulating signaling pathway GO:0002764 125 0.014
glucose metabolic process GO:0006006 92 0.014
regulation of purine nucleotide metabolic process GO:1900542 169 0.014
cation homeostasis GO:0055080 212 0.014
negative regulation of endopeptidase activity GO:0010951 44 0.014
compound eye development GO:0048749 1 0.014
Fly
regulation of glucose metabolic process GO:0010906 60 0.014
protein targeting GO:0006605 143 0.013
cofactor metabolic process GO:0051186 80 0.013
positive regulation of protein kinase activity GO:0045860 144 0.013
regulation of t cell activation GO:0050863 170 0.013
protein modification by small protein removal GO:0070646 21 0.013
establishment of vesicle localization GO:0051650 81 0.013
signal transduction involved in dna damage checkpoint GO:0072422 3 0.013
negative regulation of hydrolase activity GO:0051346 71 0.013
regulation of adaptive immune response GO:0002819 90 0.013
epithelial cell proliferation GO:0050673 174 0.013
lymphocyte proliferation GO:0046651 164 0.013
labyrinthine layer development GO:0060711 49 0.013
rna splicing GO:0008380 54 0.013
positive regulation of neuron differentiation GO:0045666 141 0.013
chromosome segregation GO:0007059 48 0.013
regulation of autophagy GO:0010506 30 0.013
peptide transport GO:0015833 133 0.013
regulation of establishment of protein localization GO:0070201 181 0.013
translation GO:0006412 93 0.013
response to epidermal growth factor GO:0070849 4 0.013
regulation of epithelial cell proliferation GO:0050678 141 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.013
amino acid transmembrane transport GO:0003333 37 0.013
positive regulation of cell cycle process GO:0090068 61 0.013
carbohydrate derivative catabolic process GO:1901136 231 0.013
female sex differentiation GO:0046660 84 0.013
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.013
extracellular matrix organization GO:0030198 147 0.013
positive regulation of jnk cascade GO:0046330 46 0.013
mesodermal cell migration GO:0008078 4 0.012
regulation of secretion by cell GO:1903530 249 0.012
positive regulation of defense response GO:0031349 124 0.012
purine ribonucleoside metabolic process GO:0046128 241 0.012
lymphocyte activation involved in immune response GO:0002285 93 0.012
regulation of binding GO:0051098 111 0.012
Mouse
response to peptide hormone GO:0043434 127 0.012
regulation of lymphocyte proliferation GO:0050670 117 0.012
negative regulation of fibroblast migration GO:0010764 2 0.012
negative regulation of neuron death GO:1901215 98 0.012
Mouse
branching morphogenesis of an epithelial tube GO:0048754 159 0.012
positive regulation of stress activated mapk cascade GO:0032874 48 0.012
mrna metabolic process GO:0016071 84 0.012
regulation of cell motility GO:2000145 236 0.012
cellular response to hypoxia GO:0071456 17 0.012
positive regulation of neuron projection regeneration GO:0070572 2 0.012
forebrain development GO:0030900 302 0.012
fatty acid transmembrane transport GO:1902001 1 0.012
regulation of protein import into nucleus GO:0042306 52 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
sequestering of calcium ion GO:0051208 18 0.012

Hipk1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.032
disease of anatomical entity DOID:7 0 0.032
disease of cellular proliferation DOID:14566 0 0.028
disease of metabolism DOID:0014667 0 0.027
inherited metabolic disorder DOID:655 0 0.027
cancer DOID:162 0 0.021
organ system cancer DOID:0050686 0 0.021
hematopoietic system disease DOID:74 0 0.017
bone disease DOID:0080001 0 0.016
musculoskeletal system disease DOID:17 0 0.016
connective tissue disease DOID:65 0 0.016
anemia DOID:2355 0 0.016
nervous system disease DOID:863 0 0.014
immune system cancer DOID:0060083 0 0.013
hematologic cancer DOID:2531 0 0.013