Mus musculus

52 known processes

Hipk4

homeodomain interacting protein kinase 4

(Aliases: Gm162)

Hipk4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amine metabolic process GO:0044106 44 0.057
cellular amino acid metabolic process GO:0006520 103 0.055
cellular ketone metabolic process GO:0042180 84 0.052
regulation of cellular ketone metabolic process GO:0010565 66 0.047
regulation of cellular amino acid metabolic process GO:0006521 5 0.047
regulation of cellular amine metabolic process GO:0033238 20 0.047
amine metabolic process GO:0009308 45 0.045
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.037
regulation of membrane potential GO:0042391 192 0.034
positive regulation of cellular amine metabolic process GO:0033240 5 0.032
multicellular organismal signaling GO:0035637 91 0.032
transmembrane transport GO:0055085 412 0.031
transmission of nerve impulse GO:0019226 76 0.029
cytokine production GO:0001816 319 0.029
regulation of protein localization GO:0032880 231 0.029
g protein coupled receptor signaling pathway GO:0007186 243 0.028
cellular homeostasis GO:0019725 240 0.027
ras protein signal transduction GO:0007265 77 0.026
neuronal action potential GO:0019228 54 0.026
ion transmembrane transport GO:0034220 361 0.025
positive regulation of protein modification process GO:0031401 299 0.024
Mouse
mapk cascade GO:0000165 281 0.024
Mouse
cation transmembrane transport GO:0098655 266 0.024
regulation of transferase activity GO:0051338 263 0.024
Mouse
organonitrogen compound catabolic process GO:1901565 264 0.024
cellular chemical homeostasis GO:0055082 215 0.023
small gtpase mediated signal transduction GO:0007264 97 0.023
cell adhesion GO:0007155 329 0.023
nucleobase containing small molecule metabolic process GO:0055086 352 0.022
peptidyl amino acid modification GO:0018193 336 0.022
regulation of establishment of protein localization GO:0070201 181 0.022
action potential GO:0001508 78 0.022
blood circulation GO:0008015 195 0.022
camera type eye development GO:0043010 266 0.022
Mouse
cation homeostasis GO:0055080 212 0.022
ossification GO:0001503 216 0.021
inorganic ion transmembrane transport GO:0098660 234 0.021
nucleotide metabolic process GO:0009117 332 0.021
organonitrogen compound biosynthetic process GO:1901566 192 0.021
negative regulation of protein metabolic process GO:0051248 282 0.021
Mouse
hematopoietic progenitor cell differentiation GO:0002244 143 0.021
nucleoside phosphate metabolic process GO:0006753 338 0.021
circulatory system process GO:0003013 197 0.021
sensory perception GO:0007600 245 0.021
forebrain development GO:0030900 302 0.021
regulation of system process GO:0044057 200 0.021
regulation of cell migration GO:0030334 219 0.020
regulation of kinase activity GO:0043549 249 0.020
Mouse
metal ion homeostasis GO:0055065 189 0.020
regulation of secretion GO:0051046 274 0.020
synaptic transmission GO:0007268 329 0.020
response to molecule of bacterial origin GO:0002237 143 0.020
ribose phosphate metabolic process GO:0019693 291 0.020
response to organonitrogen compound GO:0010243 246 0.020
cation transport GO:0006812 399 0.020
dna metabolic process GO:0006259 303 0.019
regulation of cell activation GO:0050865 289 0.019
negative regulation of phosphate metabolic process GO:0045936 184 0.019
Mouse
regulation of feeding behavior GO:0060259 3 0.019
regulation of ion transport GO:0043269 215 0.019
oxidation reduction process GO:0055114 342 0.019
regulation of cytokine production GO:0001817 266 0.019
microtubule based process GO:0007017 236 0.019
regulation of cell cycle GO:0051726 281 0.019
cellular nitrogen compound catabolic process GO:0044270 280 0.019
protein modification by small protein conjugation or removal GO:0070647 207 0.018
organic cyclic compound catabolic process GO:1901361 295 0.018
regulation of organelle organization GO:0033043 289 0.018
positive regulation of nervous system development GO:0051962 221 0.018
membrane organization GO:0061024 245 0.018
cytoplasmic transport GO:0016482 234 0.018
response to lipopolysaccharide GO:0032496 128 0.018
nitrogen compound transport GO:0071705 271 0.018
reactive oxygen species metabolic process GO:0072593 84 0.018
t cell activation GO:0042110 289 0.017
muscle tissue development GO:0060537 308 0.017
heterocycle catabolic process GO:0046700 280 0.017
cellular response to lipopolysaccharide GO:0071222 77 0.017
cellular response to lipid GO:0071396 145 0.017
purine containing compound metabolic process GO:0072521 311 0.017
regulation of hormone levels GO:0010817 211 0.017
skeletal system development GO:0001501 356 0.017
immune effector process GO:0002252 321 0.017
leukocyte differentiation GO:0002521 342 0.017
conditioned taste aversion GO:0001661 4 0.017
macromolecule catabolic process GO:0009057 281 0.017
striated muscle tissue development GO:0014706 293 0.017
spermatogenesis GO:0007283 284 0.017
cell type specific apoptotic process GO:0097285 268 0.017
Mouse
male gamete generation GO:0048232 285 0.017
aromatic compound catabolic process GO:0019439 286 0.017
regulation of anatomical structure size GO:0090066 178 0.017
carbohydrate derivative biosynthetic process GO:1901137 183 0.016
purine ribonucleotide metabolic process GO:0009150 290 0.016
negative regulation of cell proliferation GO:0008285 296 0.016
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.016
purine nucleotide metabolic process GO:0006163 302 0.016
purine nucleoside catabolic process GO:0006152 205 0.016
gland development GO:0048732 330 0.016
cellular lipid metabolic process GO:0044255 323 0.016
stem cell differentiation GO:0048863 268 0.016
regulation of secretion by cell GO:1903530 249 0.016
inflammatory response GO:0006954 244 0.016
negative regulation of cellular amine metabolic process GO:0033239 1 0.016
nucleoside metabolic process GO:0009116 246 0.016
negative regulation of phosphorus metabolic process GO:0010563 184 0.015
Mouse
muscle cell differentiation GO:0042692 261 0.015
positive regulation of transferase activity GO:0051347 167 0.015
cellular response to organonitrogen compound GO:0071417 145 0.015
locomotory behavior GO:0007626 195 0.015
Mouse
ribonucleoside metabolic process GO:0009119 245 0.015
regulation of reactive oxygen species metabolic process GO:2000377 40 0.015
wnt signaling pathway GO:0016055 188 0.015
Fly
cellular ion homeostasis GO:0006873 165 0.015
divalent inorganic cation transport GO:0072511 178 0.015
protein modification by small protein conjugation GO:0032446 187 0.015
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.015
negative regulation of intracellular signal transduction GO:1902532 167 0.015
Mouse
cellular metal ion homeostasis GO:0006875 151 0.015
calcium ion homeostasis GO:0055074 127 0.015
posttranscriptional regulation of gene expression GO:0010608 155 0.015
Fly
response to organic cyclic compound GO:0014070 198 0.015
positive regulation of cytokine production GO:0001819 174 0.015
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.015
nucleocytoplasmic transport GO:0006913 139 0.015
ribonucleotide metabolic process GO:0009259 291 0.015
purine ribonucleoside metabolic process GO:0046128 241 0.015
regulation of protein transport GO:0051223 163 0.015
nucleoside catabolic process GO:0009164 206 0.015
regulation of lymphocyte activation GO:0051249 240 0.015
regulation of neuron differentiation GO:0045664 281 0.015
carbohydrate metabolic process GO:0005975 230 0.015
divalent inorganic cation homeostasis GO:0072507 138 0.014
protein processing GO:0016485 163 0.014
endomembrane system organization GO:0010256 147 0.014
leukocyte mediated immunity GO:0002443 174 0.014
regulation of cell motility GO:2000145 236 0.014
homeostasis of number of cells GO:0048872 210 0.014
positive regulation of protein phosphorylation GO:0001934 242 0.014
Mouse
reactive nitrogen species metabolic process GO:2001057 0 0.014
regulation of cellular catabolic process GO:0031329 242 0.014
protein ubiquitination GO:0016567 171 0.014
purine nucleoside triphosphate metabolic process GO:0009144 226 0.014
apoptotic signaling pathway GO:0097190 306 0.014
Mouse
lymphocyte differentiation GO:0030098 242 0.014
hormone secretion GO:0046879 128 0.014
regulation of neuron projection development GO:0010975 169 0.014
positive regulation of kinase activity GO:0033674 155 0.014
nucleoside phosphate catabolic process GO:1901292 222 0.014
purine containing compound catabolic process GO:0072523 213 0.014
positive regulation of cell development GO:0010720 237 0.014
embryonic organ morphogenesis GO:0048562 276 0.014
Mouse
respiratory system development GO:0060541 190 0.014
carbohydrate derivative catabolic process GO:1901136 231 0.014
response to inorganic substance GO:0010035 96 0.014
central nervous system neuron differentiation GO:0021953 162 0.014
protein secretion GO:0009306 111 0.014
chemotaxis GO:0006935 247 0.014
regulation of mapk cascade GO:0043408 248 0.014
Mouse
cellular divalent inorganic cation homeostasis GO:0072503 127 0.013
inorganic cation transmembrane transport GO:0098662 207 0.013
heart process GO:0003015 94 0.013
rho protein signal transduction GO:0007266 32 0.013
blood vessel morphogenesis GO:0048514 285 0.013
multi multicellular organism process GO:0044706 109 0.013
intracellular protein transport GO:0006886 204 0.013
cellular response to biotic stimulus GO:0071216 92 0.013
microtubule cytoskeleton organization GO:0000226 157 0.013
heart morphogenesis GO:0003007 178 0.013
anion transport GO:0006820 177 0.013
negative regulation of molecular function GO:0044092 258 0.013
Mouse
regulation of action potential GO:0098900 4 0.013
reactive oxygen species biosynthetic process GO:1903409 8 0.013
regulation of response to wounding GO:1903034 189 0.013
purine nucleoside metabolic process GO:0042278 241 0.013
purine ribonucleotide catabolic process GO:0009154 208 0.013
protein maturation GO:0051604 176 0.013
positive regulation of cell death GO:0010942 224 0.013
anatomical structure homeostasis GO:0060249 145 0.013
endocytosis GO:0006897 168 0.013
regulation of apoptotic signaling pathway GO:2001233 197 0.013
negative regulation of cellular component organization GO:0051129 194 0.013
organophosphate catabolic process GO:0046434 232 0.013
cell division GO:0051301 120 0.013
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.013
regulation of t cell activation GO:0050863 170 0.013
protein catabolic process GO:0030163 221 0.013
maintenance of location GO:0051235 89 0.013
negative regulation of phosphorylation GO:0042326 166 0.013
Mouse
cellular response to molecule of bacterial origin GO:0071219 83 0.013
positive regulation of mapk cascade GO:0043410 170 0.013
regulation of protein kinase activity GO:0045859 232 0.013
Mouse
cellular response to dna damage stimulus GO:0006974 207 0.013
Mouse
response to acid chemical GO:0001101 111 0.013
regulation of homeostatic process GO:0032844 182 0.012
regulation of cell projection organization GO:0031344 206 0.012
cellular response to acid chemical GO:0071229 68 0.012
organic hydroxy compound metabolic process GO:1901615 203 0.012
positive regulation of programmed cell death GO:0043068 218 0.012
regulation of cell cycle process GO:0010564 160 0.012
actin cytoskeleton organization GO:0030036 220 0.012
organelle fission GO:0048285 170 0.012
nucleoside triphosphate catabolic process GO:0009143 205 0.012
regulation of blood pressure GO:0008217 93 0.012
regulation of ossification GO:0030278 112 0.012
tissue remodeling GO:0048771 102 0.012
nucleotide catabolic process GO:0009166 217 0.012
muscle contraction GO:0006936 101 0.012
positive regulation of protein kinase activity GO:0045860 144 0.012
muscle system process GO:0003012 141 0.012
nucleoside triphosphate metabolic process GO:0009141 230 0.012
regulation of purine nucleotide metabolic process GO:1900542 169 0.012
ribonucleoside triphosphate metabolic process GO:0009199 220 0.012
glycosyl compound metabolic process GO:1901657 246 0.012
epithelial tube morphogenesis GO:0060562 303 0.012
regulation of protein serine threonine kinase activity GO:0071900 157 0.012
Mouse
regulation of defense response GO:0031347 233 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.012
Mouse
regulation of protein secretion GO:0050708 82 0.012
tissue homeostasis GO:0001894 115 0.012
negative regulation of cellular protein metabolic process GO:0032269 247 0.012
Mouse
ribonucleotide catabolic process GO:0009261 208 0.012
sensory organ morphogenesis GO:0090596 242 0.012
Mouse
ribonucleoside catabolic process GO:0042454 206 0.012
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.012
mitotic cell cycle GO:0000278 195 0.012
plasma membrane organization GO:0007009 90 0.012
dna recombination GO:0006310 92 0.012
amide transport GO:0042886 138 0.012
myosin filament organization GO:0031033 3 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.012
regulation of cellular response to stress GO:0080135 159 0.011
Mouse
stem cell development GO:0048864 219 0.011
chromatin organization GO:0006325 206 0.011
organic anion transport GO:0015711 137 0.011
regulation of nucleotide metabolic process GO:0006140 169 0.011
activation of adenylate cyclase activity GO:0007190 4 0.011
lipid biosynthetic process GO:0008610 179 0.011
regulation of hydrolase activity GO:0051336 246 0.011
axonogenesis GO:0007409 274 0.011
multicellular organism growth GO:0035264 161 0.011
axon ensheathment GO:0008366 76 0.011
cell activation involved in immune response GO:0002263 126 0.011
leukocyte migration GO:0050900 124 0.011
fat cell differentiation GO:0045444 160 0.011
divalent metal ion transport GO:0070838 172 0.011
peptide transport GO:0015833 133 0.011
protein targeting GO:0006605 143 0.011
response to amino acid GO:0043200 37 0.011
b cell activation GO:0042113 161 0.011
response to growth factor GO:0070848 198 0.011
Mouse
sequestering of calcium ion GO:0051208 18 0.011
regulation of body fluid levels GO:0050878 162 0.011
organophosphate biosynthetic process GO:0090407 122 0.011
regulation of cellular component biogenesis GO:0044087 181 0.011
regulation of proteolysis GO:0030162 164 0.011
neural tube development GO:0021915 160 0.011
epithelial cell development GO:0002064 159 0.011
leukocyte activation involved in immune response GO:0002366 126 0.011
antimicrobial peptide production GO:0002775 2 0.011
striated muscle myosin thick filament assembly GO:0071688 1 0.011
myosin filament assembly GO:0031034 2 0.011
neuromuscular process GO:0050905 99 0.011
regulation of blood circulation GO:1903522 93 0.011
purine nucleoside triphosphate catabolic process GO:0009146 203 0.011
heart contraction GO:0060047 93 0.011
ribonucleoside triphosphate catabolic process GO:0009203 199 0.011
purine nucleotide catabolic process GO:0006195 211 0.011
lateral inhibition GO:0046331 1 0.011
protein localization to organelle GO:0033365 185 0.011
intrinsic apoptotic signaling pathway GO:0097193 132 0.011
Mouse
pharynx development GO:0060465 1 0.011
digestive system development GO:0055123 200 0.011
regulation of serotonin secretion GO:0014062 3 0.011
purine ribonucleotide biosynthetic process GO:0009152 59 0.011
nuclear division GO:0000280 158 0.011
peptide secretion GO:0002790 114 0.010
developmental maturation GO:0021700 193 0.010
rhythmic process GO:0048511 174 0.010
telencephalon development GO:0021537 186 0.010
nuclear transport GO:0051169 139 0.010
skin development GO:0043588 220 0.010
myelination GO:0042552 74 0.010
glucose homeostasis GO:0042593 128 0.010
negative regulation of protein modification process GO:0031400 163 0.010
Mouse
cardiac muscle tissue development GO:0048738 130 0.010
monocarboxylic acid metabolic process GO:0032787 191 0.010
mitotic cell cycle process GO:1903047 159 0.010
lung development GO:0030324 164 0.010
regulation of wnt signaling pathway GO:0030111 123 0.010
Fly
positive regulation of hydrolase activity GO:0051345 148 0.010
neuron migration GO:0001764 122 0.010
cellular carbohydrate metabolic process GO:0044262 119 0.010
regulation of metal ion transport GO:0010959 106 0.010
leukocyte proliferation GO:0070661 172 0.010
cytosolic calcium ion homeostasis GO:0051480 70 0.010
positive regulation of secretion GO:0051047 130 0.010
respiratory tube development GO:0030323 167 0.010
cellular protein complex assembly GO:0043623 116 0.010
response to radiation GO:0009314 165 0.010
cellular response to amino acid stimulus GO:0071230 29 0.010

Hipk4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.024
musculoskeletal system disease DOID:17 0 0.016
disease of metabolism DOID:0014667 0 0.012
sensory system disease DOID:0050155 0 0.011