Mus musculus

27 known processes

Guk1

guanylate kinase 1

(Aliases: Gmk,AA409738,AV026611,AL033299,Guk-1,AL033300)

Guk1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mitochondrion organization GO:0007005 134 0.064
negative regulation of phosphorus metabolic process GO:0010563 184 0.060
negative regulation of phosphate metabolic process GO:0045936 184 0.059
ras protein signal transduction GO:0007265 77 0.052
regulation of cellular amino acid metabolic process GO:0006521 5 0.051
cellular amine metabolic process GO:0044106 44 0.051
negative regulation of protein modification process GO:0031400 163 0.050
cellular amino acid metabolic process GO:0006520 103 0.047
regulation of cellular amine metabolic process GO:0033238 20 0.043
small gtpase mediated signal transduction GO:0007264 97 0.043
aromatic compound catabolic process GO:0019439 286 0.043
regulation of transferase activity GO:0051338 263 0.043
organic cyclic compound catabolic process GO:1901361 295 0.039
negative regulation of protein phosphorylation GO:0001933 126 0.039
negative regulation of cellular protein metabolic process GO:0032269 247 0.039
rho protein signal transduction GO:0007266 32 0.036
amine metabolic process GO:0009308 45 0.036
negative regulation of protein metabolic process GO:0051248 282 0.034
cellular ketone metabolic process GO:0042180 84 0.033
cellular lipid metabolic process GO:0044255 323 0.030
response to organic cyclic compound GO:0014070 198 0.029
activation of adenylate cyclase activity GO:0007190 4 0.028
negative regulation of phosphorylation GO:0042326 166 0.027
guanosine containing compound catabolic process GO:1901069 144 0.026
negative regulation of molecular function GO:0044092 258 0.026
mapk cascade GO:0000165 281 0.026
organophosphate biosynthetic process GO:0090407 122 0.026
regulation of kinase activity GO:0043549 249 0.026
response to organonitrogen compound GO:0010243 246 0.026
regulation of protein kinase activity GO:0045859 232 0.025
regulation of mapk cascade GO:0043408 248 0.024
reactive oxygen species metabolic process GO:0072593 84 0.023
regulation of nucleotide metabolic process GO:0006140 169 0.023
regulation of cellular ketone metabolic process GO:0010565 66 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.022
cell fate commitment GO:0045165 210 0.022
regulation of rho protein signal transduction GO:0035023 71 0.022
ribonucleoside triphosphate metabolic process GO:0009199 220 0.022
response to oxidative stress GO:0006979 123 0.021
positive regulation of cellular amine metabolic process GO:0033240 5 0.021
spermatogenesis GO:0007283 284 0.021
heterocycle catabolic process GO:0046700 280 0.021
apoptotic signaling pathway GO:0097190 306 0.020
peptidyl amino acid modification GO:0018193 336 0.020
membrane organization GO:0061024 245 0.020
nucleotide metabolic process GO:0009117 332 0.020
rap protein signal transduction GO:0032486 3 0.020
forebrain development GO:0030900 302 0.020
regulation of gtp catabolic process GO:0033124 113 0.020
regulation of purine nucleotide metabolic process GO:1900542 169 0.020
skeletal muscle organ development GO:0060538 163 0.019
positive regulation of protein modification process GO:0031401 299 0.019
positive regulation of nucleoside metabolic process GO:0045979 91 0.018
sensory organ morphogenesis GO:0090596 242 0.018
purine nucleotide metabolic process GO:0006163 302 0.018
striated muscle tissue development GO:0014706 293 0.018
response to light stimulus GO:0009416 135 0.018
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.018
regulation of cellular component biogenesis GO:0044087 181 0.018
actin cytoskeleton organization GO:0030036 220 0.018
camera type eye development GO:0043010 266 0.017
response to radiation GO:0009314 165 0.017
regulation of cellular catabolic process GO:0031329 242 0.017
regulation of nucleotide catabolic process GO:0030811 122 0.017
organophosphate catabolic process GO:0046434 232 0.017
ketone catabolic process GO:0042182 3 0.017
regulation of cell motility GO:2000145 236 0.017
regulation of organelle organization GO:0033043 289 0.017
positive regulation of mapk cascade GO:0043410 170 0.016
muscle tissue development GO:0060537 308 0.016
positive regulation of transferase activity GO:0051347 167 0.016
translation GO:0006412 93 0.016
positive regulation of nucleotide metabolic process GO:0045981 114 0.016
gtp catabolic process GO:0006184 143 0.016
regulation of apoptotic signaling pathway GO:2001233 197 0.016
nucleobase containing small molecule metabolic process GO:0055086 352 0.016
response to inorganic substance GO:0010035 96 0.016
regulation of secretion by cell GO:1903530 249 0.015
organonitrogen compound biosynthetic process GO:1901566 192 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.015
male gamete generation GO:0048232 285 0.015
negative regulation of neuron death GO:1901215 98 0.015
positive regulation of protein phosphorylation GO:0001934 242 0.015
telencephalon development GO:0021537 186 0.015
response to drug GO:0042493 75 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.015
regulation of secretion GO:0051046 274 0.015
protein localization to membrane GO:0072657 108 0.014
cellular macromolecule catabolic process GO:0044265 206 0.014
ribonucleotide catabolic process GO:0009261 208 0.014
positive regulation of programmed cell death GO:0043068 218 0.014
protein localization to organelle GO:0033365 185 0.014
protein ubiquitination GO:0016567 171 0.014
fat cell differentiation GO:0045444 160 0.013
macromolecule catabolic process GO:0009057 281 0.013
organonitrogen compound catabolic process GO:1901565 264 0.013
response to monosaccharide GO:0034284 67 0.013
negative regulation of transferase activity GO:0051348 85 0.013
regulation of purine nucleotide catabolic process GO:0033121 122 0.013
regulation of nucleoside metabolic process GO:0009118 130 0.013
inorganic ion transmembrane transport GO:0098660 234 0.013
stem cell differentiation GO:0048863 268 0.013
cell type specific apoptotic process GO:0097285 268 0.013
muscle cell differentiation GO:0042692 261 0.013
erk1 and erk2 cascade GO:0070371 77 0.012
positive regulation of nucleotide catabolic process GO:0030813 88 0.012
purine ribonucleotide metabolic process GO:0009150 290 0.012
cellular component assembly involved in morphogenesis GO:0010927 139 0.012
fatty acid metabolic process GO:0006631 121 0.012
energy derivation by oxidation of organic compounds GO:0015980 77 0.012
regulation of hormone levels GO:0010817 211 0.012
rac protein signal transduction GO:0016601 13 0.012
positive regulation of gtpase activity GO:0043547 85 0.012
glial cell differentiation GO:0010001 131 0.012
g protein coupled receptor signaling pathway GO:0007186 243 0.012
glycosyl compound metabolic process GO:1901657 246 0.012
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.012
regulation of erk1 and erk2 cascade GO:0070372 71 0.012
purine ribonucleoside catabolic process GO:0046130 205 0.012
substantia nigra development GO:0021762 2 0.011
regulation of cell projection organization GO:0031344 206 0.011
skin development GO:0043588 220 0.011
intrinsic apoptotic signaling pathway GO:0097193 132 0.011
lipid biosynthetic process GO:0008610 179 0.011
protein modification by small protein conjugation GO:0032446 187 0.011
regulation of actin cytoskeleton organization GO:0032956 84 0.011
cation transport GO:0006812 399 0.011
positive regulation of cellular catabolic process GO:0031331 148 0.011
positive regulation of kinase activity GO:0033674 155 0.011
germ cell development GO:0007281 185 0.011
purine containing compound catabolic process GO:0072523 213 0.011
nitrogen compound transport GO:0071705 271 0.011
regulation of protein localization GO:0032880 231 0.011
carbohydrate derivative biosynthetic process GO:1901137 183 0.011
cation transmembrane transport GO:0098655 266 0.011
renal system development GO:0072001 225 0.011
glycosyl compound catabolic process GO:1901658 206 0.011
regulation of muscle tissue development GO:1901861 97 0.011
regulation of neuron death GO:1901214 134 0.011
carbohydrate derivative catabolic process GO:1901136 231 0.010
gliogenesis GO:0042063 141 0.010
dephosphorylation GO:0016311 129 0.010
negative regulation of cell proliferation GO:0008285 296 0.010
leukocyte differentiation GO:0002521 342 0.010
transmembrane transport GO:0055085 412 0.010
positive regulation of apoptotic process GO:0043065 217 0.010
dna metabolic process GO:0006259 303 0.010
positive regulation of cell development GO:0010720 237 0.010
regulation of neuron projection development GO:0010975 169 0.010
response to growth factor GO:0070848 198 0.010
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.010
t cell activation GO:0042110 289 0.010
chromatin organization GO:0006325 206 0.010
carboxylic acid biosynthetic process GO:0046394 86 0.010

Guk1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.010
disease of anatomical entity DOID:7 0 0.010
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010