Mus musculus

33 known processes

Pgk2

phosphoglycerate kinase 2

(Aliases: Tcp-2,Pgk-2)

Pgk2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
monocarboxylic acid metabolic process GO:0032787 191 0.146
inflammatory response GO:0006954 244 0.143
regulation of defense response GO:0031347 233 0.101
neutrophil mediated killing of gram positive bacterium GO:0070946 2 0.100
regulation of systemic arterial blood pressure GO:0003073 61 0.094
amine metabolic process GO:0009308 45 0.089
cytokine production GO:0001816 319 0.089
regulation of inflammatory response GO:0050727 147 0.088
regulation of response to wounding GO:1903034 189 0.083
immune effector process GO:0002252 321 0.082
oxidation reduction process GO:0055114 342 0.080
granzyme mediated apoptotic signaling pathway GO:0008626 1 0.080
cellular lipid metabolic process GO:0044255 323 0.079
cellular amino acid metabolic process GO:0006520 103 0.062
cellular ketone metabolic process GO:0042180 84 0.060
protein maturation GO:0051604 176 0.057
regulation of cytokine production GO:0001817 266 0.057
regulation of cellular amino acid metabolic process GO:0006521 5 0.056
regulation of cellular ketone metabolic process GO:0010565 66 0.052
cellular amine metabolic process GO:0044106 44 0.049
disruption by host of symbiont cells GO:0051852 11 0.048
fertilization GO:0009566 127 0.047
single fertilization GO:0007338 82 0.047
action potential GO:0001508 78 0.046
defense response to bacterium GO:0042742 119 0.045
response to lipopolysaccharide GO:0032496 128 0.044
multicellular organismal signaling GO:0035637 91 0.044
reactive oxygen species metabolic process GO:0072593 84 0.042
regulation of membrane potential GO:0042391 192 0.041
spermatogenesis GO:0007283 284 0.041
macromolecule catabolic process GO:0009057 281 0.041
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.040
small gtpase mediated signal transduction GO:0007264 97 0.040
regulation of blood pressure GO:0008217 93 0.039
lipid biosynthetic process GO:0008610 179 0.039
apoptotic signaling pathway GO:0097190 306 0.039
positive regulation of cytokine production GO:0001819 174 0.038
transmission of nerve impulse GO:0019226 76 0.037
leukocyte differentiation GO:0002521 342 0.037
nuclear division GO:0000280 158 0.036
regulation of multi organism process GO:0043900 111 0.036
defense response to other organism GO:0098542 197 0.035
cellular response to organonitrogen compound GO:0071417 145 0.035
regulation of cell activation GO:0050865 289 0.035
glycosyl compound metabolic process GO:1901657 246 0.035
heterocycle catabolic process GO:0046700 280 0.035
small molecule biosynthetic process GO:0044283 132 0.034
positive regulation of cellular amine metabolic process GO:0033240 5 0.034
homeostasis of number of cells GO:0048872 210 0.033
response to molecule of bacterial origin GO:0002237 143 0.033
positive regulation of transferase activity GO:0051347 167 0.033
regulation of eosinophil migration GO:2000416 2 0.033
cell cell recognition GO:0009988 44 0.033
negative regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061179 4 0.033
muscle cell differentiation GO:0042692 261 0.032
positive regulation of apoptotic process GO:0043065 217 0.032
male gamete generation GO:0048232 285 0.032
negative regulation of defense response GO:0031348 77 0.031
endocytosis GO:0006897 168 0.031
myeloid cell differentiation GO:0030099 233 0.031
sperm egg recognition GO:0035036 37 0.031
dna metabolic process GO:0006259 303 0.031
acute inflammatory response GO:0002526 41 0.030
cognition GO:0050890 149 0.030
fatty acid metabolic process GO:0006631 121 0.029
progesterone metabolic process GO:0042448 4 0.029
neuronal action potential GO:0019228 54 0.029
negative regulation of immune system process GO:0002683 209 0.029
adaptive immune response GO:0002250 155 0.029
cellular response to lipid GO:0071396 145 0.028
regulation of anatomical structure size GO:0090066 178 0.028
protein processing GO:0016485 163 0.028
carbohydrate metabolic process GO:0005975 230 0.028
protein oligomerization GO:0051259 67 0.028
muscle system process GO:0003012 141 0.028
leukocyte proliferation GO:0070661 172 0.027
regulation of cellular response to stress GO:0080135 159 0.027
muscle tissue development GO:0060537 308 0.027
positive regulation of kinase activity GO:0033674 155 0.027
myelination GO:0042552 74 0.027
cellular response to peptide GO:1901653 92 0.027
protein catabolic process GO:0030163 221 0.026
negative regulation of cellular protein metabolic process GO:0032269 247 0.026
lymphocyte differentiation GO:0030098 242 0.025
positive regulation of cell death GO:0010942 224 0.025
cellular response to hormone stimulus GO:0032870 150 0.025
glial cell development GO:0021782 54 0.025
organic cyclic compound catabolic process GO:1901361 295 0.025
regulation of myelination GO:0031641 20 0.025
heart morphogenesis GO:0003007 178 0.025
nucleocytoplasmic transport GO:0006913 139 0.025
response to light stimulus GO:0009416 135 0.024
meiotic cell cycle GO:0051321 122 0.024
axon ensheathment GO:0008366 76 0.024
regulation of systemic arterial blood pressure by hormone GO:0001990 25 0.024
protein targeting GO:0006605 143 0.024
positive regulation of programmed cell death GO:0043068 218 0.024
carboxylic acid biosynthetic process GO:0046394 86 0.024
alpha amino acid metabolic process GO:1901605 59 0.024
heart process GO:0003015 94 0.023
ensheathment of neurons GO:0007272 76 0.023
regulation of systemic arterial blood pressure by renin angiotensin GO:0003081 20 0.023
nuclear transport GO:0051169 139 0.023
extracellular matrix organization GO:0030198 147 0.023
positive regulation of defense response GO:0031349 124 0.023
positive regulation of protein modification process GO:0031401 299 0.023
protein localization to organelle GO:0033365 185 0.023
purine ribonucleotide catabolic process GO:0009154 208 0.023
regulation of mapk cascade GO:0043408 248 0.023
regulation of t cell activation GO:0050863 170 0.023
cellular response to dna damage stimulus GO:0006974 207 0.023
germ cell development GO:0007281 185 0.023
cytoplasmic transport GO:0016482 234 0.023
positive regulation of secretion GO:0051047 130 0.022
blood circulation GO:0008015 195 0.022
regulation of cellular component size GO:0032535 121 0.022
regulation of phospholipid biosynthetic process GO:0071071 3 0.022
growth of symbiont involved in interaction with host GO:0044116 23 0.022
regulation of proteolysis GO:0030162 164 0.022
regulation of kinase activity GO:0043549 249 0.022
learning or memory GO:0007611 148 0.022
regulation of protein maturation GO:1903317 96 0.021
killing by host of symbiont cells GO:0051873 11 0.021
protein modification by small protein conjugation GO:0032446 187 0.021
mapk cascade GO:0000165 281 0.021
response to oxidative stress GO:0006979 123 0.021
regulation of hormone levels GO:0010817 211 0.021
organic acid biosynthetic process GO:0016053 86 0.021
response to testosterone GO:0033574 3 0.021
t helper 2 cell cytokine production GO:0035745 4 0.021
regulation of translation GO:0006417 71 0.021
nucleoside phosphate catabolic process GO:1901292 222 0.021
negative regulation of protein metabolic process GO:0051248 282 0.021
regulation of cellular amine metabolic process GO:0033238 20 0.021
heart contraction GO:0060047 93 0.021
regulation of protein catabolic process GO:0042176 108 0.021
organelle fission GO:0048285 170 0.021
negative regulation of cell activation GO:0050866 111 0.021
regulation of peptidase activity GO:0052547 96 0.020
regulation of leukocyte apoptotic process GO:2000106 56 0.020
rho protein signal transduction GO:0007266 32 0.020
regulation of leukocyte differentiation GO:1902105 159 0.020
response to extracellular stimulus GO:0009991 127 0.020
regulation of reactive oxygen species metabolic process GO:2000377 40 0.020
circulatory system process GO:0003013 197 0.020
translation GO:0006412 93 0.020
regulation of t cell proliferation GO:0042129 92 0.020
myeloid leukocyte differentiation GO:0002573 119 0.020
fat cell differentiation GO:0045444 160 0.020
positive regulation of membrane protein ectodomain proteolysis GO:0051044 3 0.020
positive regulation of apoptotic signaling pathway GO:2001235 95 0.020
defense response to gram positive bacterium GO:0050830 50 0.020
aromatic compound catabolic process GO:0019439 286 0.019
cellular response to cytokine stimulus GO:0071345 189 0.019
regulation of endocytosis GO:0030100 69 0.019
lymphocyte proliferation GO:0046651 164 0.019
regulation of establishment of protein localization GO:0070201 181 0.019
regulation of protein serine threonine kinase activity GO:0071900 157 0.019
rhythmic process GO:0048511 174 0.019
extracellular structure organization GO:0043062 148 0.019
regulation of lymphocyte proliferation GO:0050670 117 0.019
binding of sperm to zona pellucida GO:0007339 34 0.019
regulation of protein transport GO:0051223 163 0.019
protein homooligomerization GO:0051260 43 0.019
organic hydroxy compound metabolic process GO:1901615 203 0.019
generation of precursor metabolites and energy GO:0006091 103 0.019
regulation of feeding behavior GO:0060259 3 0.018
cation transport GO:0006812 399 0.018
regulation of transferase activity GO:0051338 263 0.018
regulation of angiotensin levels in blood GO:0002002 4 0.018
cell recognition GO:0008037 83 0.018
negative regulation of response to wounding GO:1903035 77 0.018
nucleoside metabolic process GO:0009116 246 0.018
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.018
peptidyl tyrosine modification GO:0018212 145 0.018
regulation of cell projection organization GO:0031344 206 0.018
skeletal system morphogenesis GO:0048705 203 0.018
meiotic nuclear division GO:0007126 115 0.018
regulation of apoptotic signaling pathway GO:2001233 197 0.017
cellular protein complex assembly GO:0043623 116 0.017
glycolytic process GO:0006096 20 0.017
regulation of cell cycle GO:0051726 281 0.017
lymphocyte mediated immunity GO:0002449 139 0.017
growth involved in symbiotic interaction GO:0044110 23 0.017
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.017
cell adhesion GO:0007155 329 0.017
endocrine process GO:0050886 39 0.017
purine containing compound catabolic process GO:0072523 213 0.017
negative regulation of growth GO:0045926 99 0.016
positive regulation of protein kinase activity GO:0045860 144 0.016
rna interference GO:0016246 2 0.016
killing of cells in other organism involved in symbiotic interaction GO:0051883 13 0.016
mitotic cell cycle GO:0000278 195 0.016
regulation of lymphocyte mediated immunity GO:0002706 84 0.016
regulation of postsynaptic membrane potential GO:0060078 48 0.016
intracellular protein transport GO:0006886 204 0.016
cellular nitrogen compound catabolic process GO:0044270 280 0.016
negative regulation of neuron projection regeneration GO:0070571 3 0.016
steroid metabolic process GO:0008202 119 0.016
regulation of protein processing GO:0070613 96 0.016
spermatid development GO:0007286 108 0.016
posttranscriptional regulation of gene expression GO:0010608 155 0.016
regulation of lymphocyte differentiation GO:0045619 107 0.016
regulation of lymphocyte activation GO:0051249 240 0.016
protein import GO:0017038 101 0.016
mitotic cell cycle process GO:1903047 159 0.016
glycosyl compound catabolic process GO:1901658 206 0.016
cell type specific apoptotic process GO:0097285 268 0.016
positive regulation of inflammatory response GO:0050729 47 0.016
cilium assembly GO:0042384 81 0.016
purine ribonucleoside catabolic process GO:0046130 205 0.016
regulation of complement activation classical pathway GO:0030450 1 0.016
cell killing GO:0001906 67 0.016
regulation of lipid metabolic process GO:0019216 118 0.016
regulation of protein kinase activity GO:0045859 232 0.016
regulation of cellular component biogenesis GO:0044087 181 0.016
extrinsic apoptotic signaling pathway GO:0097191 126 0.016
leukocyte activation involved in immune response GO:0002366 126 0.015
methylation GO:0032259 134 0.015
memory GO:0007613 58 0.015
regulation of innate immune response GO:0045088 91 0.015
peptidyl amino acid modification GO:0018193 336 0.015
glycoprotein metabolic process GO:0009100 116 0.015
response to organic cyclic compound GO:0014070 198 0.015
male gonad development GO:0008584 88 0.015
sperm motility GO:0030317 47 0.015
cell activation involved in immune response GO:0002263 126 0.015
eosinophil migration GO:0072677 3 0.015
development of primary sexual characteristics GO:0045137 143 0.015
negative regulation of cellular amine metabolic process GO:0033239 1 0.015
cellular component assembly involved in morphogenesis GO:0010927 139 0.015
positive regulation of thymocyte migration GO:2000412 2 0.015
mitochondrion organization GO:0007005 134 0.015
regulation of homeostatic process GO:0032844 182 0.015
disruption of cells of other organism involved in symbiotic interaction GO:0051818 13 0.015
regulation of thymocyte migration GO:2000410 2 0.015
innate immune response GO:0045087 157 0.015
regulation of vesicle mediated transport GO:0060627 139 0.015
cellular divalent inorganic cation homeostasis GO:0072503 127 0.014
ras protein signal transduction GO:0007265 77 0.014
wnt signaling pathway GO:0016055 188 0.014
cellular response to antibiotic GO:0071236 4 0.014
axonogenesis GO:0007409 274 0.014
cellular response to growth factor stimulus GO:0071363 197 0.014
purine nucleoside catabolic process GO:0006152 205 0.014
long chain fatty acid import GO:0044539 2 0.014
positive regulation of protein phosphorylation GO:0001934 242 0.014
small molecule catabolic process GO:0044282 71 0.014
lymphocyte apoptotic process GO:0070227 54 0.014
neutrophil mediated cytotoxicity GO:0070942 8 0.014
regulation of protein complex assembly GO:0043254 83 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.014
ribonucleoside metabolic process GO:0009119 245 0.014
cellular response to molecule of bacterial origin GO:0071219 83 0.014
cellular biogenic amine metabolic process GO:0006576 28 0.014
purine ribonucleoside metabolic process GO:0046128 241 0.014
morphogenesis of a branching structure GO:0001763 203 0.014
regulation of hydrolase activity GO:0051336 246 0.014
gonad development GO:0008406 141 0.014
membrane organization GO:0061024 245 0.014
tissue homeostasis GO:0001894 115 0.014
circadian rhythm GO:0007623 114 0.014
asymmetric stem cell division GO:0098722 3 0.014
organonitrogen compound catabolic process GO:1901565 264 0.014
response to radiation GO:0009314 165 0.014
spermatid differentiation GO:0048515 115 0.014
positive regulation of endocytosis GO:0045807 42 0.014
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.014
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.014
sensory perception of light stimulus GO:0050953 54 0.014
development of primary male sexual characteristics GO:0046546 88 0.014
regulation of cellular catabolic process GO:0031329 242 0.014
av node cell to bundle of his cell communication GO:0086067 2 0.014
protein activation cascade GO:0072376 19 0.014
regulation of body fluid levels GO:0050878 162 0.014
cellular carbohydrate metabolic process GO:0044262 119 0.013
ribonucleoside catabolic process GO:0042454 206 0.013
regulation of system process GO:0044057 200 0.013
carbohydrate derivative catabolic process GO:1901136 231 0.013
regulation of growth of symbiont in host GO:0044126 19 0.013
positive regulation of vasoconstriction GO:0045907 4 0.013
rna processing GO:0006396 105 0.013
single organismal cell cell adhesion GO:0016337 131 0.013
regulation of protein localization GO:0032880 231 0.013
hepaticobiliary system development GO:0061008 67 0.013
purine nucleoside triphosphate metabolic process GO:0009144 226 0.013
protein localization to nucleus GO:0034504 121 0.013
protein depolymerization GO:0051261 34 0.013
female sex differentiation GO:0046660 84 0.013
single organism nuclear import GO:1902593 95 0.013
response to nutrient levels GO:0031667 109 0.013
positive regulation of cell projection organization GO:0031346 95 0.013
cellular response to peptide hormone stimulus GO:0071375 92 0.013
regulation of phosphatidylcholine biosynthetic process GO:2001245 2 0.013
regulation of t helper 2 cell cytokine production GO:2000551 3 0.013
diterpenoid metabolic process GO:0016101 24 0.013
androgen biosynthetic process GO:0006702 4 0.013
negative regulation of cytokine production GO:0001818 84 0.013
ubiquitin dependent protein catabolic process GO:0006511 129 0.013
purine nucleoside metabolic process GO:0042278 241 0.013
sodium ion transport GO:0006814 73 0.013
guanosine containing compound catabolic process GO:1901069 144 0.013
negative regulation of cellular component organization GO:0051129 194 0.013
cellular response to biotic stimulus GO:0071216 92 0.013
macromolecule glycosylation GO:0043413 55 0.013
icosanoid metabolic process GO:0006690 33 0.013
anion transport GO:0006820 177 0.013
leukocyte mediated cytotoxicity GO:0001909 62 0.013
reactive nitrogen species metabolic process GO:2001057 0 0.013
negative regulation of molecular function GO:0044092 258 0.013
response to drug GO:0042493 75 0.012
positive regulation of eosinophil migration GO:2000418 2 0.012
regulation of angiotensin metabolic process GO:0060177 4 0.012
response to inorganic substance GO:0010035 96 0.012
thymocyte migration GO:0072679 2 0.012
negative regulation of protein processing GO:0010955 79 0.012
ribonucleotide catabolic process GO:0009261 208 0.012
purine containing compound metabolic process GO:0072521 311 0.012
regulation of secretion GO:0051046 274 0.012
negative regulation of protein maturation GO:1903318 79 0.012
anatomical structure homeostasis GO:0060249 145 0.012
actin cytoskeleton organization GO:0030036 220 0.012
regulation of organelle organization GO:0033043 289 0.012
phospholipid metabolic process GO:0006644 87 0.012
negative regulation of growth of symbiont involved in interaction with host GO:0044146 19 0.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.012
retinoic acid metabolic process GO:0042573 12 0.012
cellular macromolecule catabolic process GO:0044265 206 0.012
response to insulin GO:0032868 100 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
vasodilation GO:0042311 28 0.012
ribonucleoside triphosphate catabolic process GO:0009203 199 0.012
protein import into nucleus GO:0006606 95 0.012
striated muscle contraction GO:0006941 45 0.012
purine nucleotide catabolic process GO:0006195 211 0.012
positive regulation of mapk cascade GO:0043410 170 0.012
regulation of cytoplasmic transport GO:1903649 112 0.012
skeletal muscle cell differentiation GO:0035914 66 0.012
nucleotide metabolic process GO:0009117 332 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.012
cellular response to lipopolysaccharide GO:0071222 77 0.012
positive regulation of lipid metabolic process GO:0045834 40 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
nucleotide catabolic process GO:0009166 217 0.012
male sex differentiation GO:0046661 109 0.012
spleen development GO:0048536 39 0.011
myeloid leukocyte mediated immunity GO:0002444 42 0.011
multicellular organism growth GO:0035264 161 0.011
establishment of protein localization to organelle GO:0072594 118 0.011
b cell activation GO:0042113 161 0.011
carbohydrate catabolic process GO:0016052 32 0.011
cardiac chamber development GO:0003205 108 0.011
norepinephrine secretion GO:0048243 2 0.011
carbohydrate derivative biosynthetic process GO:1901137 183 0.011
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.011
peptide metabolic process GO:0006518 46 0.011
response to organonitrogen compound GO:0010243 246 0.011
regulation of monocyte chemotaxis GO:0090025 3 0.011
olfactory learning GO:0008355 2 0.011
cellular response to inorganic substance GO:0071241 37 0.011
cofactor metabolic process GO:0051186 80 0.011
modification of morphology or physiology of other organism GO:0035821 18 0.011
cellular amide metabolic process GO:0043603 58 0.011
nucleobase containing small molecule metabolic process GO:0055086 352 0.011
gliogenesis GO:0042063 141 0.011
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 16 0.011
cation homeostasis GO:0055080 212 0.011
locomotory behavior GO:0007626 195 0.011
striated muscle tissue development GO:0014706 293 0.011
cellular response to steroid hormone stimulus GO:0071383 33 0.011
cytokine metabolic process GO:0042107 71 0.011
regulation of ion transport GO:0043269 215 0.011
regulation of lamellipodium assembly GO:0010591 3 0.011
response to acid chemical GO:0001101 111 0.011
metal ion homeostasis GO:0055065 189 0.011
growth of symbiont in host GO:0044117 23 0.011
cellular aldehyde metabolic process GO:0006081 12 0.011
chromosome segregation GO:0007059 48 0.011
skeletal muscle organ development GO:0060538 163 0.011
alcohol metabolic process GO:0006066 116 0.011
protein kinase b signaling GO:0043491 74 0.011
oocyte construction GO:0007308 2 0.011
cellular response to extracellular stimulus GO:0031668 81 0.011
negative regulation of phosphorus metabolic process GO:0010563 184 0.010
response to vitamin a GO:0033189 1 0.010
cation transmembrane transport GO:0098655 266 0.010
negative regulation of proteolysis GO:0045861 74 0.010
dephosphorylation GO:0016311 129 0.010
leukocyte mediated immunity GO:0002443 174 0.010
membrane depolarization GO:0051899 64 0.010
regulation of leukocyte mediated immunity GO:0002703 104 0.010
positive regulation of leukocyte proliferation GO:0070665 73 0.010
glycerolipid metabolic process GO:0046486 122 0.010
leukocyte homeostasis GO:0001776 79 0.010
ion transmembrane transport GO:0034220 361 0.010
leukocyte apoptotic process GO:0071887 71 0.010
epidermis development GO:0008544 187 0.010
protein ubiquitination GO:0016567 171 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.010
regulation of cell size GO:0008361 72 0.010
purine nucleoside triphosphate catabolic process GO:0009146 203 0.010
cellular response to nutrient levels GO:0031669 64 0.010
modulation of growth of symbiont involved in interaction with host GO:0044144 19 0.010

Pgk2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.016
disease of anatomical entity DOID:7 0 0.016
musculoskeletal system disease DOID:17 0 0.016
disease of metabolism DOID:0014667 0 0.014
inherited metabolic disorder DOID:655 0 0.014
cardiovascular system disease DOID:1287 0 0.010
connective tissue disease DOID:65 0 0.010
bone disease DOID:0080001 0 0.010