Mus musculus

46 known processes

Use1

unconventional SNARE in the ER 1 homolog (S. cerevisiae)

(Aliases: Ed2,p31,D12,2010315L10Rik,AV002165,Q-snare,5730403H22Rik)

Use1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular protein catabolic process GO:0044257 155 0.217
macromolecule catabolic process GO:0009057 281 0.209
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.197
negative regulation of cellular protein metabolic process GO:0032269 247 0.195
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.144
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.122
oxidation reduction process GO:0055114 342 0.117
regulation of protein processing GO:0070613 96 0.117
modification dependent macromolecule catabolic process GO:0043632 133 0.114
negative regulation of protein modification process GO:0031400 163 0.087
negative regulation of protein metabolic process GO:0051248 282 0.085
protein maturation GO:0051604 176 0.082
negative regulation of protein processing GO:0010955 79 0.068
transmission of nerve impulse GO:0019226 76 0.068
regulation of cellular catabolic process GO:0031329 242 0.066
regulation of cellular amino acid metabolic process GO:0006521 5 0.065
cellular macromolecule catabolic process GO:0044265 206 0.058
regulation of cellular protein catabolic process GO:1903362 61 0.054
regulation of cellular amine metabolic process GO:0033238 20 0.051
inflammatory response GO:0006954 244 0.049
regulation of proteasomal protein catabolic process GO:0061136 46 0.048
cellular amine metabolic process GO:0044106 44 0.046
regulation of defense response GO:0031347 233 0.046
ubiquitin dependent protein catabolic process GO:0006511 129 0.044
protein localization to plasma membrane GO:0072659 57 0.043
membrane organization GO:0061024 245 0.041
microtubule based process GO:0007017 236 0.040
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.040
viral budding GO:0046755 1 0.039
dna metabolic process GO:0006259 303 0.039
digestive tract morphogenesis GO:0048546 147 0.037
regulation of protein catabolic process GO:0042176 108 0.035
protein catabolic process GO:0030163 221 0.033
negative regulation of proteolysis GO:0045861 74 0.032
nucleoside phosphate metabolic process GO:0006753 338 0.032
protein processing GO:0016485 163 0.031
nucleotide metabolic process GO:0009117 332 0.031
digestive system development GO:0055123 200 0.031
regulation of secretion GO:0051046 274 0.031
modification dependent protein catabolic process GO:0019941 133 0.031
microtubule cytoskeleton organization GO:0000226 157 0.030
regulation of membrane potential GO:0042391 192 0.030
cell chemotaxis GO:0060326 81 0.030
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.030
regulation of inflammatory response GO:0050727 147 0.029
regulation of protein maturation GO:1903317 96 0.028
digestive tract development GO:0048565 190 0.028
negative regulation of protein ubiquitination GO:0031397 19 0.028
cellular amino acid metabolic process GO:0006520 103 0.026
response to oxidative stress GO:0006979 123 0.026
regulation of fat cell differentiation GO:0045598 81 0.025
negative regulation of phosphate metabolic process GO:0045936 184 0.024
purine ribonucleotide metabolic process GO:0009150 290 0.023
regulation of proteolysis GO:0030162 164 0.023
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.023
negative regulation of cellular component organization GO:0051129 194 0.023
nitrogen compound transport GO:0071705 271 0.023
regulation of hormone levels GO:0010817 211 0.022
chemotaxis GO:0006935 247 0.022
action potential GO:0001508 78 0.021
regulation of apoptotic signaling pathway GO:2001233 197 0.021
positive regulation of viral process GO:0048524 5 0.021
regulation of kinase activity GO:0043549 249 0.021
vesicle organization GO:0016050 60 0.021
vesicle fusion GO:0006906 16 0.020
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.020
neuron death GO:0070997 154 0.020
purine nucleoside triphosphate metabolic process GO:0009144 226 0.019
transcription from rna polymerase iii promoter GO:0006383 3 0.019
negative regulation of cellular catabolic process GO:0031330 47 0.018
ketone catabolic process GO:0042182 3 0.018
translational initiation GO:0006413 24 0.018
negative regulation of protein modification by small protein conjugation or removal GO:1903321 20 0.018
cellular ketone metabolic process GO:0042180 84 0.018
negative regulation of protein maturation GO:1903318 79 0.017
regulation of transferase activity GO:0051338 263 0.017
translation GO:0006412 93 0.017
positive regulation of cell death GO:0010942 224 0.016
purine nucleotide metabolic process GO:0006163 302 0.016
glycosyl compound metabolic process GO:1901657 246 0.016
negative regulation of protein phosphorylation GO:0001933 126 0.016
reactive oxygen species metabolic process GO:0072593 84 0.016
amine metabolic process GO:0009308 45 0.016
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 15 0.015
multicellular organismal signaling GO:0035637 91 0.015
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.015
gene silencing GO:0016458 38 0.015
negative regulation of cell proliferation GO:0008285 296 0.015
protein localization to membrane GO:0072657 108 0.015
leukocyte migration GO:0050900 124 0.015
regulation of ion transport GO:0043269 215 0.014
virion assembly GO:0019068 1 0.014
myelination GO:0042552 74 0.014
cellular response to oxidative stress GO:0034599 76 0.014
protein modification by small protein conjugation GO:0032446 187 0.014
protein oligomerization GO:0051259 67 0.014
positive regulation of cellular amine metabolic process GO:0033240 5 0.014
regulation of vesicle mediated transport GO:0060627 139 0.014
extrinsic apoptotic signaling pathway GO:0097191 126 0.013
posttranscriptional regulation of gene expression GO:0010608 155 0.013
muscle tissue development GO:0060537 308 0.013
negative regulation of protein catabolic process GO:0042177 36 0.013
regulation of respiratory burst GO:0060263 2 0.013
regulation of cell migration GO:0030334 219 0.013
regulation of protein localization GO:0032880 231 0.013
regulation of secretion by cell GO:1903530 249 0.013
negative regulation of defense response GO:0031348 77 0.013
cellular response to organonitrogen compound GO:0071417 145 0.012
male gamete generation GO:0048232 285 0.012
neuronal action potential GO:0019228 54 0.012
organophosphate biosynthetic process GO:0090407 122 0.012
mitotic cell cycle GO:0000278 195 0.012
response to hydrogen peroxide GO:0042542 32 0.012
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 22 0.012
establishment of organelle localization GO:0051656 122 0.012
chromatin organization GO:0006325 206 0.012
gastrulation GO:0007369 116 0.012
hormone secretion GO:0046879 128 0.012
leukocyte chemotaxis GO:0030595 69 0.012
regulation of ossification GO:0030278 112 0.012
protein ubiquitination GO:0016567 171 0.012
negative regulation of neuron apoptotic process GO:0043524 92 0.012
negative regulation of intracellular signal transduction GO:1902532 167 0.012
pharynx development GO:0060465 1 0.012
negative regulation of phosphorylation GO:0042326 166 0.012
nuclear export GO:0051168 34 0.011
regulation of cell motility GO:2000145 236 0.011
nucleocytoplasmic transport GO:0006913 139 0.011
apoptotic signaling pathway GO:0097190 306 0.011
cell adhesion GO:0007155 329 0.011
regulation of neuron apoptotic process GO:0043523 122 0.011
innate immune response GO:0045087 157 0.011
proteasomal protein catabolic process GO:0010498 98 0.011
mitotic cell cycle process GO:1903047 159 0.011
glucose homeostasis GO:0042593 128 0.011
regulation of cellular ketone metabolic process GO:0010565 66 0.011
amide transport GO:0042886 138 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.011
ensheathment of neurons GO:0007272 76 0.011
regulation of response to wounding GO:1903034 189 0.010
negative regulation of immune effector process GO:0002698 55 0.010
negative regulation of neuron death GO:1901215 98 0.010
endomembrane system organization GO:0010256 147 0.010
positive regulation of cell motility GO:2000147 116 0.010
positive regulation of secretion GO:0051047 130 0.010
cellular chemical homeostasis GO:0055082 215 0.010
nucleobase containing small molecule metabolic process GO:0055086 352 0.010
plasma membrane organization GO:0007009 90 0.010
ion transmembrane transport GO:0034220 361 0.010
regulation of hydrolase activity GO:0051336 246 0.010
regulation of hormone secretion GO:0046883 88 0.010
negative regulation of cellular protein catabolic process GO:1903363 22 0.010
negative regulation of respiratory burst involved in inflammatory response GO:0060266 1 0.010
purine nucleoside metabolic process GO:0042278 241 0.010

Use1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.033
disease of anatomical entity DOID:7 0 0.033
anemia DOID:2355 0 0.022
hematopoietic system disease DOID:74 0 0.022
congenital hypoplastic anemia DOID:1342 0 0.019
aplastic anemia DOID:12449 0 0.019
bone marrow disease DOID:4961 0 0.019
disease of metabolism DOID:0014667 0 0.013