Mus musculus

12 known processes

Cops3

COP9 (constitutive photomorphogenic) homolog, subunit 3 (Arabidopsis thaliana)

(Aliases: Sgn3,Csn3)

Cops3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein modification by small protein removal GO:0070646 21 0.801
Human Fly
lateral inhibition GO:0046331 1 0.393
Fly
protein modification by small protein conjugation or removal GO:0070647 207 0.244
Human Fly
cellular response to dna damage stimulus GO:0006974 207 0.093
Fly
negative regulation of cell cycle GO:0045786 123 0.082
Fly
cell fate commitment GO:0045165 210 0.079
Fly
dna integrity checkpoint GO:0031570 28 0.077
Fly
nucleotide metabolic process GO:0009117 332 0.076
cell cycle checkpoint GO:0000075 47 0.074
Fly
mitotic cell cycle process GO:1903047 159 0.069
Worm Fly
regulation of mitotic cell cycle phase transition GO:1901990 73 0.069
Fly
cell division GO:0051301 120 0.065
Worm
cellular protein catabolic process GO:0044257 155 0.060
Worm
negative regulation of cell cycle process GO:0010948 69 0.059
Fly
mitotic cell cycle GO:0000278 195 0.058
Worm Fly
cell cell signaling involved in cell fate commitment GO:0045168 35 0.054
Fly
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.052
Worm
negative regulation of cell cycle phase transition GO:1901988 48 0.048
Fly
ribose phosphate metabolic process GO:0019693 291 0.045
macromolecule catabolic process GO:0009057 281 0.045
Worm
ribonucleotide metabolic process GO:0009259 291 0.043
purine containing compound metabolic process GO:0072521 311 0.043
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.040
Fly
regulation of proteolysis GO:0030162 164 0.038
organelle fission GO:0048285 170 0.038
negative regulation of mitotic cell cycle GO:0045930 58 0.037
Fly
regulation of cell cycle phase transition GO:1901987 77 0.037
Fly
purine nucleotide metabolic process GO:0006163 302 0.036
regulation of cellular amino acid metabolic process GO:0006521 5 0.036
nucleoside phosphate metabolic process GO:0006753 338 0.036
modification dependent macromolecule catabolic process GO:0043632 133 0.033
Worm
regulation of cellular amine metabolic process GO:0033238 20 0.033
ribonucleoside triphosphate metabolic process GO:0009199 220 0.033
cellular amine metabolic process GO:0044106 44 0.033
regulation of protein stability GO:0031647 52 0.033
Fly
protein maturation GO:0051604 176 0.032
modification dependent protein catabolic process GO:0019941 133 0.032
Worm
regulation of cell cycle process GO:0010564 160 0.032
Fly
nucleoside metabolic process GO:0009116 246 0.031
mrna metabolic process GO:0016071 84 0.031
germ cell development GO:0007281 185 0.030
ribonucleoside metabolic process GO:0009119 245 0.030
organelle assembly GO:0070925 177 0.030
protein stabilization GO:0050821 25 0.029
Fly
positive regulation of protein modification process GO:0031401 299 0.029
dna repair GO:0006281 107 0.029
protein catabolic process GO:0030163 221 0.029
Worm
mitotic cell cycle checkpoint GO:0007093 31 0.028
Fly
carbohydrate derivative biosynthetic process GO:1901137 183 0.028
regulation of cellular protein catabolic process GO:1903362 61 0.028
purine ribonucleotide metabolic process GO:0009150 290 0.028
nucleobase containing small molecule metabolic process GO:0055086 352 0.027
purine nucleoside triphosphate metabolic process GO:0009144 226 0.027
regulation of cellular ketone metabolic process GO:0010565 66 0.027
carbohydrate derivative catabolic process GO:1901136 231 0.027
regulation of cellular catabolic process GO:0031329 242 0.026
amine metabolic process GO:0009308 45 0.026
positive regulation of cellular amine metabolic process GO:0033240 5 0.026
cellular amino acid metabolic process GO:0006520 103 0.026
cellular ketone metabolic process GO:0042180 84 0.025
heterocycle catabolic process GO:0046700 280 0.025
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.025
posttranscriptional regulation of gene expression GO:0010608 155 0.025
Fly
protein ubiquitination GO:0016567 171 0.025
regulation of transferase activity GO:0051338 263 0.024
purine ribonucleoside metabolic process GO:0046128 241 0.024
aromatic compound catabolic process GO:0019439 286 0.023
regulation of proteasomal protein catabolic process GO:0061136 46 0.023
regulation of mapk cascade GO:0043408 248 0.023
negative regulation of protein maturation GO:1903318 79 0.022
negative regulation of cellular protein metabolic process GO:0032269 247 0.022
positive regulation of hydrolase activity GO:0051345 148 0.022
ubiquitin dependent protein catabolic process GO:0006511 129 0.022
Worm
regulation of protein catabolic process GO:0042176 108 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.022
intracellular protein transport GO:0006886 204 0.022
peptidyl amino acid modification GO:0018193 336 0.022
positive regulation of cellular catabolic process GO:0031331 148 0.021
proteasomal protein catabolic process GO:0010498 98 0.021
protein localization to nucleus GO:0034504 121 0.021
organophosphate catabolic process GO:0046434 232 0.021
purine ribonucleoside catabolic process GO:0046130 205 0.021
regulation of protein processing GO:0070613 96 0.021
protein modification by small protein conjugation GO:0032446 187 0.021
mitotic g2 dna damage checkpoint GO:0007095 8 0.020
Fly
negative regulation of protein processing GO:0010955 79 0.020
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.020
transmembrane transport GO:0055085 412 0.020
purine nucleoside metabolic process GO:0042278 241 0.020
ion transmembrane transport GO:0034220 361 0.020
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.019
organonitrogen compound catabolic process GO:1901565 264 0.019
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.019
regulation of organelle organization GO:0033043 289 0.019
regulation of protein localization GO:0032880 231 0.019
purine nucleotide catabolic process GO:0006195 211 0.019
atp metabolic process GO:0046034 75 0.018
nucleoside triphosphate catabolic process GO:0009143 205 0.018
nucleotide catabolic process GO:0009166 217 0.018
cellular macromolecule catabolic process GO:0044265 206 0.018
Worm
ribonucleotide catabolic process GO:0009261 208 0.018
molting cycle GO:0042303 90 0.018
synaptic transmission GO:0007268 329 0.018
oocyte axis specification GO:0007309 2 0.018
purine ribonucleotide catabolic process GO:0009154 208 0.018
regulation of cellular component biogenesis GO:0044087 181 0.017
fertilization GO:0009566 127 0.017
organic cyclic compound catabolic process GO:1901361 295 0.017
mapk cascade GO:0000165 281 0.017
protein localization to organelle GO:0033365 185 0.017
oocyte anterior posterior axis specification GO:0007314 2 0.017
translation GO:0006412 93 0.017
gonad development GO:0008406 141 0.017
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.017
glycosyl compound metabolic process GO:1901657 246 0.016
nuclear division GO:0000280 158 0.016
regulation of translation GO:0006417 71 0.016
stem cell differentiation GO:0048863 268 0.016
regulation of transmembrane transport GO:0034762 128 0.016
ribonucleoside catabolic process GO:0042454 206 0.016
rna splicing GO:0008380 54 0.016
nucleoside phosphate catabolic process GO:1901292 222 0.016
methylation GO:0032259 134 0.016
small gtpase mediated signal transduction GO:0007264 97 0.016
negative regulation of protein metabolic process GO:0051248 282 0.016
mrna processing GO:0006397 63 0.016
maternal determination of anterior posterior axis embryo GO:0008358 2 0.016
nucleoside monophosphate metabolic process GO:0009123 85 0.016
single fertilization GO:0007338 82 0.015
membrane organization GO:0061024 245 0.015
response to organonitrogen compound GO:0010243 246 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.015
regulation of intracellular transport GO:0032386 159 0.015
spermatid development GO:0007286 108 0.015
oocyte construction GO:0007308 2 0.015
rna processing GO:0006396 105 0.015
regulation of establishment of protein localization GO:0070201 181 0.015
negative regulation of cellular component organization GO:0051129 194 0.015
ras protein signal transduction GO:0007265 77 0.015
ribonucleoside monophosphate metabolic process GO:0009161 80 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.015
positive regulation of cellular protein catabolic process GO:1903364 34 0.015
cytoplasmic transport GO:0016482 234 0.015
positive regulation of protein catabolic process GO:0045732 60 0.015
purine nucleoside triphosphate catabolic process GO:0009146 203 0.014
axonogenesis GO:0007409 274 0.014
male gamete generation GO:0048232 285 0.014
organonitrogen compound biosynthetic process GO:1901566 192 0.014
blood circulation GO:0008015 195 0.014
heart process GO:0003015 94 0.014
nucleoside triphosphate metabolic process GO:0009141 230 0.014
cellular response to organonitrogen compound GO:0071417 145 0.014
negative regulation of protein catabolic process GO:0042177 36 0.014
locomotory behavior GO:0007626 195 0.014
nucleocytoplasmic transport GO:0006913 139 0.014
regulation of cellular response to stress GO:0080135 159 0.014
nitrogen compound transport GO:0071705 271 0.014
nuclear transport GO:0051169 139 0.014
ribonucleoside triphosphate catabolic process GO:0009203 199 0.014
developmental maturation GO:0021700 193 0.014
regulation of ion transport GO:0043269 215 0.014
purine nucleoside monophosphate metabolic process GO:0009126 81 0.014
spindle assembly involved in mitosis GO:0090307 4 0.014
positive regulation of apoptotic process GO:0043065 217 0.014
cellular protein complex assembly GO:0043623 116 0.013
cation transport GO:0006812 399 0.013
regulation of purine nucleotide metabolic process GO:1900542 169 0.013
circulatory system process GO:0003013 197 0.013
embryonic organ morphogenesis GO:0048562 276 0.013
spermatogenesis GO:0007283 284 0.013
cation transmembrane transport GO:0098655 266 0.013
regulation of kinase activity GO:0043549 249 0.013
regulation of hydrolase activity GO:0051336 246 0.013
purine containing compound catabolic process GO:0072523 213 0.013
macromolecule methylation GO:0043414 120 0.013
anion transport GO:0006820 177 0.013
nucleoside catabolic process GO:0009164 206 0.013
stress activated mapk cascade GO:0051403 80 0.013
monocarboxylic acid metabolic process GO:0032787 191 0.013
inorganic cation transmembrane transport GO:0098662 207 0.013
negative regulation of phosphorus metabolic process GO:0010563 184 0.013
gliogenesis GO:0042063 141 0.013
microtubule cytoskeleton organization GO:0000226 157 0.013
Worm
inorganic ion transmembrane transport GO:0098660 234 0.013
regulation of ion transmembrane transport GO:0034765 119 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.013
ribonucleoside monophosphate catabolic process GO:0009158 57 0.013
camera type eye development GO:0043010 266 0.013
organic acid biosynthetic process GO:0016053 86 0.013
endocytosis GO:0006897 168 0.012
negative regulation of intracellular signal transduction GO:1902532 167 0.012
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.012
positive regulation of programmed cell death GO:0043068 218 0.012
anatomical structure homeostasis GO:0060249 145 0.012
cellular homeostasis GO:0019725 240 0.012
regulation of binding GO:0051098 111 0.012
cell maturation GO:0048469 127 0.012
regulation of hormone levels GO:0010817 211 0.012
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.012
regulation of protein maturation GO:1903317 96 0.012
peptidyl serine phosphorylation GO:0018105 74 0.012
synapse organization GO:0050808 125 0.012
cellular nitrogen compound catabolic process GO:0044270 280 0.012
regulation of membrane potential GO:0042391 192 0.012
apoptotic signaling pathway GO:0097190 306 0.012
nucleoside monophosphate catabolic process GO:0009125 59 0.012
regulation of cell division GO:0051302 76 0.012
skeletal system development GO:0001501 356 0.011
protein import into nucleus GO:0006606 95 0.011
purine nucleoside catabolic process GO:0006152 205 0.011
regulation of cell cycle GO:0051726 281 0.011
Fly
response to lipopolysaccharide GO:0032496 128 0.011
negative regulation of phosphate metabolic process GO:0045936 184 0.011
activation of nf kappab inducing kinase activity GO:0007250 4 0.011
regulation of system process GO:0044057 200 0.011
chromatin modification GO:0016568 187 0.011
spermatid differentiation GO:0048515 115 0.011
nuclear import GO:0051170 95 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
glycosyl compound catabolic process GO:1901658 206 0.011
cell type specific apoptotic process GO:0097285 268 0.011
neural precursor cell proliferation GO:0061351 121 0.010
protein secretion GO:0009306 111 0.010
regulation of protein transport GO:0051223 163 0.010
positive regulation of kinase activity GO:0033674 155 0.010
response to molecule of bacterial origin GO:0002237 143 0.010
actin cytoskeleton organization GO:0030036 220 0.010
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 31 0.010
cell growth GO:0016049 130 0.010
muscle system process GO:0003012 141 0.010
negative regulation of cellular catabolic process GO:0031330 47 0.010
regulation of nucleotide metabolic process GO:0006140 169 0.010
microtubule based process GO:0007017 236 0.010
Worm
positive regulation of transferase activity GO:0051347 167 0.010
heart contraction GO:0060047 93 0.010

Cops3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.016
musculoskeletal system disease DOID:17 0 0.011