Mus musculus

0 known processes

Cops6

COP9 (constitutive photomorphogenic) homolog, subunit 6 (Arabidopsis thaliana)

(Aliases: VIP/MOV34,Sgn3)

Cops6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein modification by small protein removal GO:0070646 21 0.994
Human
protein modification by small protein conjugation or removal GO:0070647 207 0.770
Human
lateral inhibition GO:0046331 1 0.500
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.392
modification dependent protein catabolic process GO:0019941 133 0.331
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.331
cellular response to dna damage stimulus GO:0006974 207 0.319
modification dependent macromolecule catabolic process GO:0043632 133 0.303
cellular macromolecule catabolic process GO:0044265 206 0.210
regulation of cell cycle process GO:0010564 160 0.186
cellular protein catabolic process GO:0044257 155 0.180
negative regulation of cell cycle GO:0045786 123 0.156
ubiquitin dependent protein catabolic process GO:0006511 129 0.142
mitotic g2 dna damage checkpoint GO:0007095 8 0.140
cell division GO:0051301 120 0.137
Worm
protein processing GO:0016485 163 0.128
positive regulation of cellular catabolic process GO:0031331 148 0.126
exosomal secretion GO:1990182 1 0.125
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.123
regulation of protein stability GO:0031647 52 0.121
negative regulation of protein processing GO:0010955 79 0.121
gonad development GO:0008406 141 0.120
stress activated protein kinase signaling cascade GO:0031098 81 0.116
cell cell signaling involved in cell fate commitment GO:0045168 35 0.115
positive regulation of protein modification process GO:0031401 299 0.113
negative regulation of cell cycle phase transition GO:1901988 48 0.100
protein stabilization GO:0050821 25 0.094
purine ribonucleotide metabolic process GO:0009150 290 0.094
purine ribonucleoside metabolic process GO:0046128 241 0.094
posttranscriptional regulation of gene expression GO:0010608 155 0.092
mitotic cell cycle GO:0000278 195 0.091
mitotic cell cycle process GO:1903047 159 0.090
negative regulation of cellular protein catabolic process GO:1903363 22 0.090
regulation of mitotic cell cycle phase transition GO:1901990 73 0.089
regulation of membrane potential GO:0042391 192 0.088
regulation of cellular catabolic process GO:0031329 242 0.087
stress activated mapk cascade GO:0051403 80 0.081
cell fate commitment GO:0045165 210 0.079
regulation of cellular protein catabolic process GO:1903362 61 0.078
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.078
cytokinesis GO:0000910 17 0.075
Worm
regulation of transferase activity GO:0051338 263 0.074
regulation of cell cycle phase transition GO:1901987 77 0.073
regulation of cell cycle GO:0051726 281 0.072
ribonucleoside triphosphate metabolic process GO:0009199 220 0.071
oocyte axis specification GO:0007309 2 0.070
mitotic cytokinesis GO:0000281 4 0.070
amine metabolic process GO:0009308 45 0.069
regulation of protein processing GO:0070613 96 0.068
macromolecule catabolic process GO:0009057 281 0.068
negative regulation of proteolysis GO:0045861 74 0.066
negative regulation of cell cycle process GO:0010948 69 0.065
exocytosis GO:0006887 121 0.063
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.062
regulation of nucleotide metabolic process GO:0006140 169 0.061
protein catabolic process GO:0030163 221 0.061
dna damage checkpoint GO:0000077 26 0.059
proteasomal protein catabolic process GO:0010498 98 0.057
negative regulation of protein metabolic process GO:0051248 282 0.056
regulation of cellular amino acid metabolic process GO:0006521 5 0.056
guanosine containing compound metabolic process GO:1901068 144 0.053
organelle assembly GO:0070925 177 0.053
regulation of proteolysis GO:0030162 164 0.053
ribonucleotide metabolic process GO:0009259 291 0.052
mapk cascade GO:0000165 281 0.052
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 15 0.052
negative regulation of protein maturation GO:1903318 79 0.051
protein maturation GO:0051604 176 0.050
regulation of mitotic cell cycle GO:0007346 126 0.050
purine containing compound metabolic process GO:0072521 311 0.050
developmental maturation GO:0021700 193 0.049
cell cycle checkpoint GO:0000075 47 0.049
regulation of protein maturation GO:1903317 96 0.048
ribonucleoside metabolic process GO:0009119 245 0.047
regulation of nucleoside metabolic process GO:0009118 130 0.047
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.046
t cell activation GO:0042110 289 0.046
regulation of stress activated mapk cascade GO:0032872 69 0.045
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.045
hydrogen transport GO:0006818 35 0.044
cellular amine metabolic process GO:0044106 44 0.044
negative regulation of mitotic cell cycle GO:0045930 58 0.044
purine nucleotide metabolic process GO:0006163 302 0.043
positive regulation of nucleoside metabolic process GO:0045979 91 0.043
nucleotide metabolic process GO:0009117 332 0.043
positive regulation of cellular amine metabolic process GO:0033240 5 0.043
nucleoside triphosphate metabolic process GO:0009141 230 0.042
reactive oxygen species biosynthetic process GO:1903409 8 0.042
nucleoside metabolic process GO:0009116 246 0.041
jnk cascade GO:0007254 72 0.041
cellular ketone metabolic process GO:0042180 84 0.040
negative regulation of ligase activity GO:0051352 3 0.040
regulation of cellular response to stress GO:0080135 159 0.039
regulation of mapk cascade GO:0043408 248 0.039
regulation of proteasomal protein catabolic process GO:0061136 46 0.039
gliogenesis GO:0042063 141 0.039
regulation of gtp catabolic process GO:0033124 113 0.038
ribose phosphate metabolic process GO:0019693 291 0.038
gtp catabolic process GO:0006184 143 0.038
purine nucleoside triphosphate metabolic process GO:0009144 226 0.037
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.037
negative regulation of cellular protein metabolic process GO:0032269 247 0.037
negative regulation of protein catabolic process GO:0042177 36 0.035
positive regulation of transferase activity GO:0051347 167 0.035
cation transport GO:0006812 399 0.035
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.035
mitotic cell cycle checkpoint GO:0007093 31 0.035
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.034
positive regulation of protein phosphorylation GO:0001934 242 0.034
cellular lipid metabolic process GO:0044255 323 0.034
positive regulation of cell cycle GO:0045787 92 0.033
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.033
negative regulation of phosphate metabolic process GO:0045936 184 0.033
regulation of jnk cascade GO:0046328 62 0.033
cation transmembrane transport GO:0098655 266 0.031
interleukin 8 production GO:0032637 4 0.031
dna integrity checkpoint GO:0031570 28 0.030
inorganic ion transmembrane transport GO:0098660 234 0.030
removal of superoxide radicals GO:0019430 12 0.030
maternal determination of anterior posterior axis embryo GO:0008358 2 0.030
dna metabolic process GO:0006259 303 0.029
organonitrogen compound biosynthetic process GO:1901566 192 0.029
leukocyte differentiation GO:0002521 342 0.029
guanosine containing compound catabolic process GO:1901069 144 0.028
regulation of purine nucleotide metabolic process GO:1900542 169 0.028
cellular amino acid metabolic process GO:0006520 103 0.028
positive regulation of proteolysis GO:0045862 85 0.028
regulation of oxidative phosphorylation GO:0002082 6 0.027
regulation of purine nucleotide catabolic process GO:0033121 122 0.027
nucleobase containing small molecule metabolic process GO:0055086 352 0.027
inorganic cation transmembrane transport GO:0098662 207 0.027
regulation of protein kinase activity GO:0045859 232 0.027
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.027
positive regulation of nucleotide metabolic process GO:0045981 114 0.027
protein localization to nucleus GO:0034504 121 0.027
positive regulation of gtp catabolic process GO:0033126 85 0.026
cell maturation GO:0048469 127 0.026
regulation of cellular ketone metabolic process GO:0010565 66 0.026
activation of nf kappab inducing kinase activity GO:0007250 4 0.026
microtubule cytoskeleton organization GO:0000226 157 0.026
calcium ion transport GO:0006816 159 0.026
regulation of kinase activity GO:0043549 249 0.026
purine nucleoside triphosphate catabolic process GO:0009146 203 0.026
axonogenesis GO:0007409 274 0.026
ribonucleoside monophosphate metabolic process GO:0009161 80 0.025
regulation of hormone levels GO:0010817 211 0.025
carbohydrate derivative biosynthetic process GO:1901137 183 0.025
divalent inorganic cation transport GO:0072511 178 0.024
regulation of protein catabolic process GO:0042176 108 0.024
regulation of ligase activity GO:0051340 10 0.024
microtubule based process GO:0007017 236 0.024
proton transport GO:0015992 35 0.023
cellular aldehyde metabolic process GO:0006081 12 0.023
peptidyl amino acid modification GO:0018193 336 0.023
purine ribonucleoside catabolic process GO:0046130 205 0.023
adult behavior GO:0030534 135 0.023
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.022
oocyte construction GO:0007308 2 0.022
regulation of hydrolase activity GO:0051336 246 0.022
protein ubiquitination GO:0016567 171 0.022
development of primary sexual characteristics GO:0045137 143 0.022
protein oxidation GO:0018158 2 0.022
positive regulation of hydrolase activity GO:0051345 148 0.022
cellular amino acid biosynthetic process GO:0008652 22 0.022
regulation of organelle organization GO:0033043 289 0.021
regulation of protein transport GO:0051223 163 0.021
extracellular matrix organization GO:0030198 147 0.021
positive regulation of membrane potential GO:0045838 15 0.021
extracellular structure organization GO:0043062 148 0.021
positive regulation of gtpase activity GO:0043547 85 0.020
response to organonitrogen compound GO:0010243 246 0.020
lymphocyte differentiation GO:0030098 242 0.020
aldehyde catabolic process GO:0046185 4 0.020
peptidyl serine phosphorylation GO:0018105 74 0.020
nucleotide catabolic process GO:0009166 217 0.020
alpha beta t cell activation GO:0046631 91 0.020
positive regulation of cellular protein catabolic process GO:1903364 34 0.020
transmembrane transport GO:0055085 412 0.020
purine nucleoside metabolic process GO:0042278 241 0.020
lactate biosynthetic process GO:0019249 4 0.020
ribose phosphate biosynthetic process GO:0046390 59 0.020
g2 dna damage checkpoint GO:0031572 8 0.019
positive regulation of interleukin 8 production GO:0032757 2 0.019
nitrogen compound transport GO:0071705 271 0.019
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.019
positive regulation of protein catabolic process GO:0045732 60 0.019
organic hydroxy compound transport GO:0015850 93 0.019
protein modification by small protein conjugation GO:0032446 187 0.019
ketone catabolic process GO:0042182 3 0.019
regulation of cellular amine metabolic process GO:0033238 20 0.019
energy derivation by oxidation of organic compounds GO:0015980 77 0.019
organelle localization GO:0051640 179 0.019
cellular divalent inorganic cation homeostasis GO:0072503 127 0.019
divalent metal ion transport GO:0070838 172 0.018
cellular homeostasis GO:0019725 240 0.018
glycosyl compound metabolic process GO:1901657 246 0.018
negative regulation of intracellular signal transduction GO:1902532 167 0.018
regulation of removal of superoxide radicals GO:2000121 4 0.018
regulation of mitochondrial membrane potential GO:0051881 17 0.018
regulation of leukocyte differentiation GO:1902105 159 0.017
divalent inorganic cation homeostasis GO:0072507 138 0.017
negative regulation of phosphorylation GO:0042326 166 0.017
regulation of cell activation GO:0050865 289 0.017
cellular modified amino acid metabolic process GO:0006575 63 0.017
regulation of establishment of protein localization GO:0070201 181 0.017
t cell proliferation GO:0042098 120 0.017
regulation of ion transport GO:0043269 215 0.017
dopamine uptake involved in synaptic transmission GO:0051583 4 0.017
negative regulation of molecular function GO:0044092 258 0.017
gtp metabolic process GO:0046039 144 0.017
regulation of reactive oxygen species metabolic process GO:2000377 40 0.017
positive regulation of cytokine production GO:0001819 174 0.017
striated muscle tissue development GO:0014706 293 0.016
cation homeostasis GO:0055080 212 0.016
calcium ion homeostasis GO:0055074 127 0.016
protein secretion GO:0009306 111 0.016
oocyte development GO:0048599 33 0.016
negative regulation of cellular catabolic process GO:0031330 47 0.016
germ cell development GO:0007281 185 0.016
cytokine production GO:0001816 319 0.016
nucleoside phosphate metabolic process GO:0006753 338 0.016
neurotransmitter transport GO:0006836 76 0.016
leukocyte proliferation GO:0070661 172 0.016
negative regulation of transferase activity GO:0051348 85 0.016
negative regulation of phosphorus metabolic process GO:0010563 184 0.016
purine nucleotide catabolic process GO:0006195 211 0.016
positive regulation of kinase activity GO:0033674 155 0.016
regulation of neurotransmitter levels GO:0001505 87 0.016
regulation of intracellular transport GO:0032386 159 0.016
antigen receptor mediated signaling pathway GO:0050851 64 0.015
alpha amino acid metabolic process GO:1901605 59 0.015
positive regulation of nucleotide catabolic process GO:0030813 88 0.015
cellular ion homeostasis GO:0006873 165 0.015
regulation of protein localization to nucleus GO:1900180 60 0.015
positive regulation of protein kinase activity GO:0045860 144 0.015
alcohol metabolic process GO:0006066 116 0.015
negative regulation of cell proliferation GO:0008285 296 0.015
ribonucleotide biosynthetic process GO:0009260 59 0.015
regulation of oxidative phosphorylation uncoupler activity GO:2000275 3 0.015
small molecule biosynthetic process GO:0044283 132 0.015
regulation of secretion by cell GO:1903530 249 0.015
nucleoside phosphate catabolic process GO:1901292 222 0.015
regulation of nucleotide catabolic process GO:0030811 122 0.015
cellular chemical homeostasis GO:0055082 215 0.015
carbohydrate derivative catabolic process GO:1901136 231 0.014
myeloid cell differentiation GO:0030099 233 0.014
rhythmic process GO:0048511 174 0.014
organophosphate biosynthetic process GO:0090407 122 0.014
membrane organization GO:0061024 245 0.014
respiratory system development GO:0060541 190 0.014
immune effector process GO:0002252 321 0.014
positive regulation of peptidyl serine phosphorylation GO:0033138 25 0.014
negative regulation of kinase activity GO:0033673 81 0.014
metal ion homeostasis GO:0055065 189 0.014
ion transmembrane transport GO:0034220 361 0.014
organic hydroxy compound biosynthetic process GO:1901617 77 0.014
regulation of protein localization GO:0032880 231 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.014
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.014
regulation of transmembrane transport GO:0034762 128 0.014
cellular protein complex assembly GO:0043623 116 0.014
regulation of interleukin 8 production GO:0032677 3 0.014
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.014
wnt signaling pathway GO:0016055 188 0.014
stem cell differentiation GO:0048863 268 0.013
intracellular protein transport GO:0006886 204 0.013
nucleotide biosynthetic process GO:0009165 78 0.013
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.013
ribonucleoside triphosphate catabolic process GO:0009203 199 0.013
ribonucleotide catabolic process GO:0009261 208 0.013
regulation of rho protein signal transduction GO:0035023 71 0.013
trna wobble uridine modification GO:0002098 2 0.013
leukocyte mediated immunity GO:0002443 174 0.013
negative regulation of immune system process GO:0002683 209 0.013
inflammatory response GO:0006954 244 0.013
skeletal system development GO:0001501 356 0.013
membrane depolarization GO:0051899 64 0.013
hormone metabolic process GO:0042445 86 0.013
muscle tissue development GO:0060537 308 0.013
regulation of secretion GO:0051046 274 0.013
nucleocytoplasmic transport GO:0006913 139 0.013
protein import into nucleus GO:0006606 95 0.012
locomotory behavior GO:0007626 195 0.012
organic hydroxy compound metabolic process GO:1901615 203 0.012
fatty acid metabolic process GO:0006631 121 0.012
regulation of cellular component biogenesis GO:0044087 181 0.012
response to organic cyclic compound GO:0014070 198 0.012
synaptic transmission GO:0007268 329 0.012
organophosphate catabolic process GO:0046434 232 0.012
positive regulation of ion transport GO:0043270 65 0.012
signal transduction in absence of ligand GO:0038034 55 0.012
regulation of cytokine production GO:0001817 266 0.012
regulation of lymphocyte activation GO:0051249 240 0.012
nuclear import GO:0051170 95 0.012
coenzyme biosynthetic process GO:0009108 23 0.012
reactive oxygen species metabolic process GO:0072593 84 0.012
protein oligomerization GO:0051259 67 0.012
t cell differentiation GO:0030217 174 0.012
ribonucleoside monophosphate biosynthetic process GO:0009156 9 0.012
peptidyl serine modification GO:0018209 83 0.012
heterocycle catabolic process GO:0046700 280 0.012
regulation of t cell activation GO:0050863 170 0.012
ribonucleoside catabolic process GO:0042454 206 0.012
purine containing compound biosynthetic process GO:0072522 70 0.012
atp metabolic process GO:0046034 75 0.012
negative regulation of binding GO:0051100 39 0.012
regulation of feeding behavior GO:0060259 3 0.012
protein localization to organelle GO:0033365 185 0.012
regulation of atp metabolic process GO:1903578 17 0.011
dephosphorylation GO:0016311 129 0.011
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.011
regulation of protein ubiquitination GO:0031396 52 0.011
dopamine uptake GO:0090494 4 0.011
extrinsic apoptotic signaling pathway GO:0097191 126 0.011
monoamine transport GO:0015844 33 0.011
monocarboxylic acid biosynthetic process GO:0072330 61 0.011
regulation of inflammatory response GO:0050727 147 0.011
regulation of lymphocyte differentiation GO:0045619 107 0.011
nucleoside phosphate biosynthetic process GO:1901293 79 0.011
action potential GO:0001508 78 0.011
nucleoside triphosphate catabolic process GO:0009143 205 0.011
small gtpase mediated signal transduction GO:0007264 97 0.011
regulation of peptidyl serine phosphorylation GO:0033135 39 0.011
regulation of androgen receptor signaling pathway GO:0060765 3 0.011
maintenance of location GO:0051235 89 0.011
respiratory tube development GO:0030323 167 0.011
purine ribonucleotide catabolic process GO:0009154 208 0.011
response to superoxide GO:0000303 16 0.011
cd4 positive alpha beta t cell activation GO:0035710 45 0.011
proteasome assembly GO:0043248 1 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.011
regulation of protein serine threonine kinase activity GO:0071900 157 0.011
cellular response to oxygen radical GO:0071450 14 0.010
regulation of intracellular protein transport GO:0033157 82 0.010
purine nucleotide biosynthetic process GO:0006164 65 0.010

Cops6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.046
disease of anatomical entity DOID:7 0 0.019
nervous system disease DOID:863 0 0.019
sensory system disease DOID:0050155 0 0.017
eye and adnexa disease DOID:1492 0 0.017
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
eye disease DOID:5614 0 0.010