Mus musculus

30 known processes

Rps6kb2

ribosomal protein S6 kinase, polypeptide 2

(Aliases: S6K2,70kDa)

Rps6kb2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of protein phosphorylation GO:0001934 242 0.081
cell adhesion GO:0007155 329 0.079
protein processing GO:0016485 163 0.073
Mouse
negative regulation of protein metabolic process GO:0051248 282 0.070
regulation of cell cycle GO:0051726 281 0.065
Mouse
male gamete generation GO:0048232 285 0.061
aromatic compound catabolic process GO:0019439 286 0.059
protein maturation GO:0051604 176 0.059
Mouse
stem cell differentiation GO:0048863 268 0.059
mapk cascade GO:0000165 281 0.058
Mouse
nitrogen compound transport GO:0071705 271 0.058
regulation of cellular catabolic process GO:0031329 242 0.058
Worm Fly
regulation of mapk cascade GO:0043408 248 0.057
Mouse
cellular ketone metabolic process GO:0042180 84 0.054
membrane organization GO:0061024 245 0.054
skeletal system development GO:0001501 356 0.054
protein localization to organelle GO:0033365 185 0.053
macromolecule catabolic process GO:0009057 281 0.053
nucleoside catabolic process GO:0009164 206 0.052
cell type specific apoptotic process GO:0097285 268 0.051
Mouse
vesicle localization GO:0051648 86 0.051
regulation of organelle organization GO:0033043 289 0.050
Mouse Worm
synaptic transmission GO:0007268 329 0.050
skin development GO:0043588 220 0.049
transmembrane transport GO:0055085 412 0.049
regulation of protein serine threonine kinase activity GO:0071900 157 0.047
regulation of protein kinase activity GO:0045859 232 0.047
regulation of proteolysis GO:0030162 164 0.045
purine nucleoside triphosphate catabolic process GO:0009146 203 0.045
negative regulation of cellular protein metabolic process GO:0032269 247 0.042
nucleobase containing small molecule metabolic process GO:0055086 352 0.041
regulation of cellular ketone metabolic process GO:0010565 66 0.041
cellular nitrogen compound catabolic process GO:0044270 280 0.040
purine ribonucleotide metabolic process GO:0009150 290 0.040
regulation of transferase activity GO:0051338 263 0.039
amine metabolic process GO:0009308 45 0.039
establishment of organelle localization GO:0051656 122 0.038
positive regulation of mapk cascade GO:0043410 170 0.038
myeloid cell differentiation GO:0030099 233 0.038
regulation of vesicle mediated transport GO:0060627 139 0.037
peptidyl amino acid modification GO:0018193 336 0.037
Mouse
stem cell development GO:0048864 219 0.037
organelle fission GO:0048285 170 0.037
Mouse
actin cytoskeleton organization GO:0030036 220 0.037
Fly
response to molecule of bacterial origin GO:0002237 143 0.036
Mouse
cation transport GO:0006812 399 0.036
purine containing compound metabolic process GO:0072521 311 0.036
multi multicellular organism process GO:0044706 109 0.035
apoptotic signaling pathway GO:0097190 306 0.035
Mouse
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.035
regulation of system process GO:0044057 200 0.035
cognition GO:0050890 149 0.034
positive regulation of programmed cell death GO:0043068 218 0.034
tissue homeostasis GO:0001894 115 0.034
modification dependent protein catabolic process GO:0019941 133 0.034
endocytosis GO:0006897 168 0.033
Fly
regulation of endocytosis GO:0030100 69 0.033
nuclear division GO:0000280 158 0.033
Mouse
glycosyl compound metabolic process GO:1901657 246 0.033
positive regulation of protein modification process GO:0031401 299 0.033
maintenance of location GO:0051235 89 0.032
positive regulation of cell death GO:0010942 224 0.031
nucleoside phosphate metabolic process GO:0006753 338 0.030
regulation of protein localization GO:0032880 231 0.030
cytoplasmic transport GO:0016482 234 0.030
striated muscle tissue development GO:0014706 293 0.029
establishment of vesicle localization GO:0051650 81 0.029
spermatogenesis GO:0007283 284 0.029
regulation of map kinase activity GO:0043405 120 0.029
cellular amino acid metabolic process GO:0006520 103 0.029
nucleoside metabolic process GO:0009116 246 0.029
purine nucleoside metabolic process GO:0042278 241 0.029
regulation of cellular amino acid metabolic process GO:0006521 5 0.029
inflammatory response GO:0006954 244 0.028
regulation of body fluid levels GO:0050878 162 0.028
microtubule based process GO:0007017 236 0.028
muscle tissue development GO:0060537 308 0.028
negative regulation of cellular component organization GO:0051129 194 0.028
Mouse
negative regulation of molecular function GO:0044092 258 0.028
protein catabolic process GO:0030163 221 0.028
regulation of anatomical structure size GO:0090066 178 0.028
Fly
cellular response to organonitrogen compound GO:0071417 145 0.028
regulation of cell adhesion GO:0030155 154 0.028
ribonucleoside triphosphate catabolic process GO:0009203 199 0.028
synaptic vesicle transport GO:0048489 57 0.027
oxidation reduction process GO:0055114 342 0.027
cellular response to hormone stimulus GO:0032870 150 0.027
chromatin organization GO:0006325 206 0.027
regulation of neuron differentiation GO:0045664 281 0.027
ribose phosphate metabolic process GO:0019693 291 0.027
ribonucleoside triphosphate metabolic process GO:0009199 220 0.027
myeloid cell homeostasis GO:0002262 114 0.026
blood circulation GO:0008015 195 0.026
Mouse
compound eye development GO:0048749 1 0.026
organelle localization GO:0051640 179 0.026
posttranscriptional regulation of gene expression GO:0010608 155 0.026
Human
positive regulation of kinase activity GO:0033674 155 0.026
positive regulation of cell development GO:0010720 237 0.026
epidermis development GO:0008544 187 0.026
embryonic organ morphogenesis GO:0048562 276 0.026
organic cyclic compound catabolic process GO:1901361 295 0.025
homeostasis of number of cells GO:0048872 210 0.025
cellular amine metabolic process GO:0044106 44 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.025
response to organonitrogen compound GO:0010243 246 0.025
regulation of apoptotic signaling pathway GO:2001233 197 0.025
Mouse
modification dependent macromolecule catabolic process GO:0043632 133 0.024
cellular response to peptide GO:1901653 92 0.024
dna metabolic process GO:0006259 303 0.024
germ cell development GO:0007281 185 0.024
Mouse Fly
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.024
response to organic cyclic compound GO:0014070 198 0.024
organonitrogen compound catabolic process GO:1901565 264 0.024
carbohydrate derivative catabolic process GO:1901136 231 0.024
regulation of homeostatic process GO:0032844 182 0.024
sensory perception GO:0007600 245 0.024
nucleoside triphosphate metabolic process GO:0009141 230 0.023
multicellular organismal homeostasis GO:0048871 164 0.023
regulation of kinase activity GO:0043549 249 0.023
ubiquitin dependent protein catabolic process GO:0006511 129 0.023
nucleotide catabolic process GO:0009166 217 0.023
cellular response to molecule of bacterial origin GO:0071219 83 0.023
ribonucleotide catabolic process GO:0009261 208 0.023
positive regulation of cell activation GO:0050867 158 0.023
phospholipid transfer to membrane GO:0006649 2 0.023
cellular macromolecule catabolic process GO:0044265 206 0.022
ras protein signal transduction GO:0007265 77 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.022
regulation of protein maturation GO:1903317 96 0.022
Mouse
engulfment of apoptotic cell GO:0043652 3 0.022
protein modification by small protein conjugation or removal GO:0070647 207 0.022
ion transmembrane transport GO:0034220 361 0.022
skeletal system morphogenesis GO:0048705 203 0.022
gtp catabolic process GO:0006184 143 0.022
response to peptide GO:1901652 136 0.022
carbohydrate derivative biosynthetic process GO:1901137 183 0.021
cellular protein catabolic process GO:0044257 155 0.021
regulation of hydrolase activity GO:0051336 246 0.021
regulation of actin filament based process GO:0032970 99 0.021
negative regulation of cell development GO:0010721 169 0.021
cellular response to lipopolysaccharide GO:0071222 77 0.021
protein localization to nucleus GO:0034504 121 0.021
heterocycle catabolic process GO:0046700 280 0.021
wnt signaling pathway GO:0016055 188 0.020
respiratory system development GO:0060541 190 0.020
anion transport GO:0006820 177 0.020
nucleotide metabolic process GO:0009117 332 0.020
positive regulation of apoptotic process GO:0043065 217 0.020
glycoprotein metabolic process GO:0009100 116 0.020
purine ribonucleoside catabolic process GO:0046130 205 0.020
regulation of ion transport GO:0043269 215 0.020
adult behavior GO:0030534 135 0.020
cellular response to peptide hormone stimulus GO:0071375 92 0.020
establishment of protein localization to membrane GO:0090150 54 0.020
regulation of cell migration GO:0030334 219 0.020
neuron death GO:0070997 154 0.020
regulation of cell activation GO:0050865 289 0.019
purine nucleotide catabolic process GO:0006195 211 0.019
intracellular protein transport GO:0006886 204 0.019
establishment of synaptic vesicle localization GO:0097480 57 0.019
response to lipopolysaccharide GO:0032496 128 0.019
Mouse
ribonucleoside metabolic process GO:0009119 245 0.019
nucleoside triphosphate catabolic process GO:0009143 205 0.019
protein methylation GO:0006479 81 0.019
sensory organ morphogenesis GO:0090596 242 0.019
regulation of cell motility GO:2000145 236 0.019
positive regulation of transferase activity GO:0051347 167 0.019
establishment of protein localization to organelle GO:0072594 118 0.019
spermatid development GO:0007286 108 0.019
purine nucleoside triphosphate metabolic process GO:0009144 226 0.019
ribonucleotide metabolic process GO:0009259 291 0.019
neural tube development GO:0021915 160 0.018
leukocyte differentiation GO:0002521 342 0.018
regulation of cytoskeleton organization GO:0051493 122 0.018
ossification GO:0001503 216 0.018
lung development GO:0030324 164 0.018
microtubule cytoskeleton organization GO:0000226 157 0.018
cellularization GO:0007349 1 0.018
oocyte axis specification GO:0007309 2 0.018
anatomical structure homeostasis GO:0060249 145 0.018
protein modification by small protein conjugation GO:0032446 187 0.018
purine nucleoside catabolic process GO:0006152 205 0.018
chemotaxis GO:0006935 247 0.018
Fly
mitochondrion organization GO:0007005 134 0.018
skeletal muscle organ development GO:0060538 163 0.018
chromatin modification GO:0016568 187 0.017
necrotic cell death GO:0070265 30 0.017
inorganic cation transmembrane transport GO:0098662 207 0.017
purine ribonucleoside metabolic process GO:0046128 241 0.017
retina development in camera type eye GO:0060041 119 0.017
regulation of feeding behavior GO:0060259 3 0.017
actin filament organization GO:0007015 113 0.017
Fly
organophosphate catabolic process GO:0046434 232 0.017
negative regulation of nervous system development GO:0051961 156 0.017
olfactory learning GO:0008355 2 0.017
cation homeostasis GO:0055080 212 0.017
response to insulin GO:0032868 100 0.017
lipid localization GO:0010876 126 0.017
negative regulation of protein modification process GO:0031400 163 0.017
regulation of actin cytoskeleton organization GO:0032956 84 0.017
cellular response to biotic stimulus GO:0071216 92 0.017
cellular lipid metabolic process GO:0044255 323 0.016
regulation of cellular component biogenesis GO:0044087 181 0.016
Worm
cellular response to growth factor stimulus GO:0071363 197 0.016
ameboidal type cell migration GO:0001667 128 0.016
response to radiation GO:0009314 165 0.016
cytokine production GO:0001816 319 0.016
purine nucleotide metabolic process GO:0006163 302 0.016
positive regulation of reverse cholesterol transport GO:1903064 1 0.016
purine containing compound catabolic process GO:0072523 213 0.016
innate immune response GO:0045087 157 0.016
Mouse
positive regulation of organelle organization GO:0010638 128 0.016
Worm
epithelial tube morphogenesis GO:0060562 303 0.016
proteasomal protein catabolic process GO:0010498 98 0.016
respiratory tube development GO:0030323 167 0.016
nucleoside phosphate catabolic process GO:1901292 222 0.016
rhythmic process GO:0048511 174 0.016
rna processing GO:0006396 105 0.016
regulation of wnt signaling pathway GO:0030111 123 0.016
regulation of protein processing GO:0070613 96 0.016
Mouse
gland development GO:0048732 330 0.016
protein localization to membrane GO:0072657 108 0.016
endomembrane system organization GO:0010256 147 0.016
stem cell maintenance GO:0019827 130 0.016
extrinsic apoptotic signaling pathway GO:0097191 126 0.016
Mouse
small molecule biosynthetic process GO:0044283 132 0.016
tube closure GO:0060606 91 0.016
purine ribonucleotide catabolic process GO:0009154 208 0.015
organic acid biosynthetic process GO:0016053 86 0.015
regulation of response to wounding GO:1903034 189 0.015
regulation of cell projection organization GO:0031344 206 0.015
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.015
development of primary sexual characteristics GO:0045137 143 0.015
methylation GO:0032259 134 0.015
neuron apoptotic process GO:0051402 142 0.015
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.015
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.015
oocyte construction GO:0007308 2 0.015
carbohydrate metabolic process GO:0005975 230 0.015
response to inorganic substance GO:0010035 96 0.015
tissue remodeling GO:0048771 102 0.015
regulation of defense response GO:0031347 233 0.015
Mouse
positive regulation of cellular component biogenesis GO:0044089 94 0.015
Worm
response to peptide hormone GO:0043434 127 0.014
positive regulation of protein kinase activity GO:0045860 144 0.014
dephosphorylation GO:0016311 129 0.014
protein polymerization GO:0051258 57 0.014
cell substrate adhesion GO:0031589 130 0.014
cellular response to insulin stimulus GO:0032869 78 0.014
regulation of cellular amine metabolic process GO:0033238 20 0.014
cellular response to dna damage stimulus GO:0006974 207 0.014
Fly
positive regulation of gtpase activity GO:0043547 85 0.014
response to growth factor GO:0070848 198 0.014
angiogenesis GO:0001525 201 0.014
locomotory behavior GO:0007626 195 0.014
synaptic vesicle localization GO:0097479 59 0.014
regulation of intracellular transport GO:0032386 159 0.014
regulation of secretion by cell GO:1903530 249 0.014
ribonucleoside catabolic process GO:0042454 206 0.014
negative regulation of proteolysis GO:0045861 74 0.014
negative regulation of protein phosphorylation GO:0001933 126 0.014
regulation of pancreatic juice secretion GO:0090186 4 0.014
cellular response to lipid GO:0071396 145 0.014
glycosyl compound catabolic process GO:1901658 206 0.014
satellite cell activation involved in skeletal muscle regeneration GO:0014901 3 0.014
embryonic epithelial tube formation GO:0001838 130 0.014
atp metabolic process GO:0046034 75 0.013
cellular homeostasis GO:0019725 240 0.013
lipid homeostasis GO:0055088 63 0.013
blood vessel morphogenesis GO:0048514 285 0.013
primary neural tube formation GO:0014020 95 0.013
regulation of engulfment of apoptotic cell GO:1901074 2 0.013
guanosine containing compound metabolic process GO:1901068 144 0.013
circadian rhythm GO:0007623 114 0.013
protein ubiquitination GO:0016567 171 0.013
macromolecule methylation GO:0043414 120 0.013
mitotic cell cycle process GO:1903047 159 0.013
cellular response to acid chemical GO:0071229 68 0.013
forebrain development GO:0030900 302 0.013
regulation of purine nucleotide catabolic process GO:0033121 122 0.013
positive regulation of stress activated mapk cascade GO:0032874 48 0.013
regulation of purine nucleotide metabolic process GO:1900542 169 0.013
wound healing GO:0042060 157 0.013
synapse organization GO:0050808 125 0.013
Fly
plasma membrane organization GO:0007009 90 0.013
regulation of secretion GO:0051046 274 0.013
monocarboxylic acid metabolic process GO:0032787 191 0.013
metencephalon development GO:0022037 89 0.013
regulation of neuron death GO:1901214 134 0.013
negative regulation of phosphorus metabolic process GO:0010563 184 0.013
Mouse
regulation of protein catabolic process GO:0042176 108 0.013
carbohydrate transport GO:0008643 62 0.013
cellular response to cytokine stimulus GO:0071345 189 0.013
regulation of myeloid cell differentiation GO:0045637 96 0.013
peptide transport GO:0015833 133 0.013
organonitrogen compound biosynthetic process GO:1901566 192 0.012
myeloid leukocyte differentiation GO:0002573 119 0.012
lipid biosynthetic process GO:0008610 179 0.012
lipoprotein metabolic process GO:0042157 43 0.012
cation transmembrane transport GO:0098655 266 0.012
organelle assembly GO:0070925 177 0.012
Worm
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.012
regulation of nucleotide catabolic process GO:0030811 122 0.012
hexose transport GO:0008645 56 0.012
lateral inhibition GO:0046331 1 0.012
small gtpase mediated signal transduction GO:0007264 97 0.012
histone modification GO:0016570 159 0.012
lipid transport GO:0006869 98 0.012
carboxylic acid biosynthetic process GO:0046394 86 0.012
cell fate commitment GO:0045165 210 0.012
mesenchyme development GO:0060485 152 0.012
protein alkylation GO:0008213 81 0.012
organic hydroxy compound metabolic process GO:1901615 203 0.012
peptidyl serine modification GO:0018209 83 0.012
Mouse
regulation of protein stability GO:0031647 52 0.012
response to light stimulus GO:0009416 135 0.012
inorganic ion transmembrane transport GO:0098660 234 0.012
regulation of establishment of protein localization GO:0070201 181 0.012
spermatid differentiation GO:0048515 115 0.012
glycoprotein biosynthetic process GO:0009101 89 0.012
cellular protein complex assembly GO:0043623 116 0.012
blastocyst development GO:0001824 80 0.012
positive regulation of cell adhesion GO:0045785 80 0.012
digestive tract development GO:0048565 190 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.012
meiotic cell cycle GO:0051321 122 0.012
Mouse
negative regulation of wnt signaling pathway GO:0030178 73 0.012
learning or memory GO:0007611 148 0.012
neural tube closure GO:0001843 90 0.012
regulation of protein complex assembly GO:0043254 83 0.012
response to oxygen levels GO:0070482 62 0.012
regulation of inflammatory response GO:0050727 147 0.012
synaptic vesicle recycling GO:0036465 19 0.012
intrinsic apoptotic signaling pathway GO:0097193 132 0.011
glycerolipid metabolic process GO:0046486 122 0.011
multi organism behavior GO:0051705 62 0.011
negative regulation of neuron death GO:1901215 98 0.011
extracellular structure organization GO:0043062 148 0.011
regulation of satellite cell activation involved in skeletal muscle regeneration GO:0014717 3 0.011
anion transmembrane transport GO:0098656 71 0.011
regulation of skeletal muscle fiber development GO:0048742 36 0.011
organic anion transport GO:0015711 137 0.011
mitotic cell cycle GO:0000278 195 0.011
cell maturation GO:0048469 127 0.011
Mouse
peptidyl lysine modification GO:0018205 77 0.011
cellular chemical homeostasis GO:0055082 215 0.011
regulation of nucleotide metabolic process GO:0006140 169 0.011
positive regulation of neuron differentiation GO:0045666 141 0.011
sequestering of metal ion GO:0051238 19 0.011
covalent chromatin modification GO:0016569 163 0.011
neural tube formation GO:0001841 108 0.011
regulation of stress activated mapk cascade GO:0032872 69 0.011
tube formation GO:0035148 140 0.011
morphogenesis of embryonic epithelium GO:0016331 159 0.011
amide transport GO:0042886 138 0.011
cartilage development GO:0051216 140 0.011
bone development GO:0060348 120 0.011
metal ion homeostasis GO:0055065 189 0.011
regulation of beta amyloid clearance GO:1900221 1 0.011
circulatory system process GO:0003013 197 0.011
Mouse
regulation of jnk cascade GO:0046328 62 0.011
regulation of cell cycle process GO:0010564 160 0.011
Mouse
myotube differentiation GO:0014902 105 0.011
Fly
positive regulation of apoptotic signaling pathway GO:2001235 95 0.011
morphogenesis of a polarized epithelium GO:0001738 37 0.011
regulation of lipoprotein lipase activity GO:0051004 4 0.011
negative regulation of glycoprotein metabolic process GO:1903019 3 0.011
immune effector process GO:0002252 321 0.011
immune response regulating signaling pathway GO:0002764 125 0.011
Mouse
intracellular mrna localization GO:0008298 4 0.010
regionalization GO:0003002 337 0.010
erythrocyte differentiation GO:0030218 88 0.010
meiotic nuclear division GO:0007126 115 0.010
Mouse
peptidyl serine phosphorylation GO:0018105 74 0.010
Mouse
cellular ion homeostasis GO:0006873 165 0.010
gtp metabolic process GO:0046039 144 0.010
memory GO:0007613 58 0.010
positive regulation of cellular amine metabolic process GO:0033240 5 0.010
body fluid secretion GO:0007589 53 0.010
regulation of cytokine production GO:0001817 266 0.010
organophosphate biosynthetic process GO:0090407 122 0.010
b cell activation GO:0042113 161 0.010
regulation of binding GO:0051098 111 0.010
i kappab kinase nf kappab signaling GO:0007249 85 0.010
glucose homeostasis GO:0042593 128 0.010
monosaccharide transport GO:0015749 58 0.010
sterol transport GO:0015918 38 0.010
regulation of blood pressure GO:0008217 93 0.010
Mouse
negative regulation of protein processing GO:0010955 79 0.010
positive regulation of nucleotide catabolic process GO:0030813 88 0.010

Rps6kb2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.050
nervous system disease DOID:863 0 0.050
central nervous system disease DOID:331 0 0.018
musculoskeletal system disease DOID:17 0 0.014
neurodegenerative disease DOID:1289 0 0.011