Mus musculus

64 known processes

Setd1a

SET domain containing 1A

(Aliases: KMT2F,mNSC1,Nsccn1,mKIAA0339,MGC55143,BC010250)

Setd1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
covalent chromatin modification GO:0016569 163 0.194
chromatin modification GO:0016568 187 0.107
histone modification GO:0016570 159 0.102
chromatin organization GO:0006325 206 0.094
dna metabolic process GO:0006259 303 0.084
embryonic organ morphogenesis GO:0048562 276 0.080
regulation of cell cycle process GO:0010564 160 0.063
organelle fission GO:0048285 170 0.060
regulation of neuron apoptotic process GO:0043523 122 0.058
negative regulation of protein metabolic process GO:0051248 282 0.056
germ cell development GO:0007281 185 0.054
stem cell maintenance GO:0019827 130 0.054
regulation of cell cycle GO:0051726 281 0.050
cellular response to dna damage stimulus GO:0006974 207 0.047
meiotic cell cycle GO:0051321 122 0.047
striated muscle tissue development GO:0014706 293 0.046
gonad development GO:0008406 141 0.044
cell adhesion GO:0007155 329 0.043
meiotic nuclear division GO:0007126 115 0.043
forebrain development GO:0030900 302 0.042
macromolecule catabolic process GO:0009057 281 0.042
multicellular organism growth GO:0035264 161 0.040
macromolecule methylation GO:0043414 120 0.037
negative regulation of cellular component organization GO:0051129 194 0.037
neuron apoptotic process GO:0051402 142 0.037
mitotic cell cycle GO:0000278 195 0.036
regulation of organelle organization GO:0033043 289 0.036
histone methylation GO:0016571 71 0.036
epithelial tube morphogenesis GO:0060562 303 0.035
circulatory system process GO:0003013 197 0.035
dna recombination GO:0006310 92 0.035
male gamete generation GO:0048232 285 0.035
modification dependent macromolecule catabolic process GO:0043632 133 0.034
protein maturation GO:0051604 176 0.034
dna repair GO:0006281 107 0.034
protein catabolic process GO:0030163 221 0.033
muscle tissue development GO:0060537 308 0.033
neuron death GO:0070997 154 0.032
modification dependent protein catabolic process GO:0019941 133 0.032
adaptive immune response GO:0002250 155 0.032
formation of organ boundary GO:0010160 1 0.032
positive regulation of cellular component biogenesis GO:0044089 94 0.031
extracellular structure organization GO:0043062 148 0.031
regionalization GO:0003002 337 0.031
cation transmembrane transport GO:0098655 266 0.031
leukocyte differentiation GO:0002521 342 0.031
spermatogenesis GO:0007283 284 0.029
developmental maturation GO:0021700 193 0.029
response to growth factor GO:0070848 198 0.029
cell fate commitment GO:0045165 210 0.028
myeloid cell differentiation GO:0030099 233 0.028
nuclear division GO:0000280 158 0.027
negative regulation of neuron death GO:1901215 98 0.027
actin cytoskeleton organization GO:0030036 220 0.027
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.027
cell type specific apoptotic process GO:0097285 268 0.026
lymphocyte mediated immunity GO:0002449 139 0.026
protein processing GO:0016485 163 0.026
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.026
axon guidance GO:0007411 141 0.026
regulation of chromosome organization GO:0033044 83 0.026
negative regulation of molecular function GO:0044092 258 0.026
inner ear morphogenesis GO:0042472 101 0.025
homeostasis of number of cells GO:0048872 210 0.025
protein alkylation GO:0008213 81 0.025
muscle cell differentiation GO:0042692 261 0.024
skeletal system morphogenesis GO:0048705 203 0.024
protein modification by small protein conjugation or removal GO:0070647 207 0.024
alpha beta t cell activation GO:0046631 91 0.024
regulation of chromatin modification GO:1903308 57 0.024
response to radiation GO:0009314 165 0.024
regulation of neuron death GO:1901214 134 0.024
positive regulation of cell death GO:0010942 224 0.024
regulation of proteolysis GO:0030162 164 0.023
blood circulation GO:0008015 195 0.023
skeletal system development GO:0001501 356 0.023
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.023
cell maturation GO:0048469 127 0.022
ubiquitin dependent protein catabolic process GO:0006511 129 0.022
cellular macromolecule catabolic process GO:0044265 206 0.021
histone h3 acetylation GO:0043966 14 0.021
reactive oxygen species metabolic process GO:0072593 84 0.021
lymphocyte differentiation GO:0030098 242 0.021
regulation of lymphocyte activation GO:0051249 240 0.021
ion transmembrane transport GO:0034220 361 0.021
positive regulation of apoptotic process GO:0043065 217 0.021
immunoglobulin mediated immune response GO:0016064 69 0.021
ear morphogenesis GO:0042471 118 0.021
spermatid differentiation GO:0048515 115 0.020
cellular protein catabolic process GO:0044257 155 0.020
regulation of stem cell proliferation GO:0072091 78 0.020
oocyte axis specification GO:0007309 2 0.020
stem cell differentiation GO:0048863 268 0.020
chemotaxis GO:0006935 247 0.020
segmentation GO:0035282 93 0.020
cellular lipid metabolic process GO:0044255 323 0.020
sensory perception GO:0007600 245 0.020
positive regulation of organelle organization GO:0010638 128 0.020
b cell activation GO:0042113 161 0.019
response to organic cyclic compound GO:0014070 198 0.019
leukocyte mediated immunity GO:0002443 174 0.019
neuroblast differentiation GO:0014016 2 0.019
rhythmic process GO:0048511 174 0.019
gland development GO:0048732 330 0.019
stem cell proliferation GO:0072089 117 0.019
spermatid development GO:0007286 108 0.019
immune effector process GO:0002252 321 0.019
negative regulation of organelle organization GO:0010639 90 0.018
skin development GO:0043588 220 0.018
transmembrane transport GO:0055085 412 0.018
negative regulation of cell cycle GO:0045786 123 0.018
embryonic skeletal system development GO:0048706 120 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.018
limb development GO:0060173 166 0.018
methylation GO:0032259 134 0.018
proteasomal protein catabolic process GO:0010498 98 0.018
positive regulation of programmed cell death GO:0043068 218 0.018
regulation of membrane potential GO:0042391 192 0.017
regulation of cellular component biogenesis GO:0044087 181 0.017
cytoplasmic transport GO:0016482 234 0.017
rna processing GO:0006396 105 0.017
regulation of cellular catabolic process GO:0031329 242 0.017
cell division GO:0051301 120 0.017
regulation of t cell activation GO:0050863 170 0.017
negative regulation of protein processing GO:0010955 79 0.017
regulation of histone methylation GO:0031060 30 0.017
regulation of kinase activity GO:0043549 249 0.017
mitotic cell cycle process GO:1903047 159 0.017
regulation of protein maturation GO:1903317 96 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.017
positive regulation of nervous system development GO:0051962 221 0.017
phospholipid metabolic process GO:0006644 87 0.017
hexose metabolic process GO:0019318 98 0.017
response to light stimulus GO:0009416 135 0.017
positive regulation of leukocyte mediated immunity GO:0002705 70 0.016
cognition GO:0050890 149 0.016
organic anion transport GO:0015711 137 0.016
immunoglobulin production GO:0002377 73 0.016
cell cycle g1 s phase transition GO:0044843 57 0.016
protein modification by small protein conjugation GO:0032446 187 0.016
activation of immune response GO:0002253 138 0.016
asymmetric stem cell division GO:0098722 3 0.016
sensory organ morphogenesis GO:0090596 242 0.016
negative regulation of chromosome organization GO:2001251 30 0.016
dephosphorylation GO:0016311 129 0.016
regulation of chromatin organization GO:1902275 57 0.016
regulation of nuclear division GO:0051783 56 0.016
sensory perception of mechanical stimulus GO:0050954 107 0.016
posttranscriptional regulation of gene expression GO:0010608 155 0.015
regulation of hydrolase activity GO:0051336 246 0.015
actin filament organization GO:0007015 113 0.015
female sex differentiation GO:0046660 84 0.015
respiratory system development GO:0060541 190 0.015
stem cell development GO:0048864 219 0.015
negative regulation of neuron apoptotic process GO:0043524 92 0.015
regulation of apoptotic signaling pathway GO:2001233 197 0.015
negative regulation of cellular protein metabolic process GO:0032269 247 0.015
synapse organization GO:0050808 125 0.015
small gtpase mediated signal transduction GO:0007264 97 0.015
protein methylation GO:0006479 81 0.015
wnt signaling pathway GO:0016055 188 0.014
female gamete generation GO:0007292 74 0.014
nucleocytoplasmic transport GO:0006913 139 0.014
negative regulation of calcium ion dependent exocytosis GO:0045955 3 0.014
cellular response to growth factor stimulus GO:0071363 197 0.014
regulation of leukocyte mediated immunity GO:0002703 104 0.014
leukocyte proliferation GO:0070661 172 0.014
protein ubiquitination GO:0016567 171 0.014
skeletal muscle organ development GO:0060538 163 0.014
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.014
regulation of cellular ketone metabolic process GO:0010565 66 0.014
cellular response to hormone stimulus GO:0032870 150 0.014
anion transport GO:0006820 177 0.014
regulation of protein processing GO:0070613 96 0.014
innate immune response GO:0045087 157 0.014
regulation of cellular amine metabolic process GO:0033238 20 0.014
hematopoietic progenitor cell differentiation GO:0002244 143 0.014
myeloid cell homeostasis GO:0002262 114 0.014
regulation of lymphocyte differentiation GO:0045619 107 0.014
organelle assembly GO:0070925 177 0.013
regulation of histone modification GO:0031056 56 0.013
sensory perception of sound GO:0007605 97 0.013
negative regulation of synaptic vesicle transport GO:1902804 3 0.013
ras protein signal transduction GO:0007265 77 0.013
cellularization GO:0007349 1 0.013
regulation of cell cycle phase transition GO:1901987 77 0.013
regulation of mitotic cell cycle GO:0007346 126 0.013
glycoprotein metabolic process GO:0009100 116 0.013
learning or memory GO:0007611 148 0.013
negative regulation of cell size GO:0045792 3 0.013
endocytosis GO:0006897 168 0.013
inorganic cation transmembrane transport GO:0098662 207 0.013
regulation of stem cell differentiation GO:2000736 50 0.013
cartilage development GO:0051216 140 0.013
neuron migration GO:0001764 122 0.013
positive regulation of cell cycle GO:0045787 92 0.013
t cell proliferation GO:0042098 120 0.013
glial cell differentiation GO:0010001 131 0.013
myeloid leukocyte differentiation GO:0002573 119 0.013
bone development GO:0060348 120 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.013
t cell differentiation GO:0030217 174 0.013
gliogenesis GO:0042063 141 0.013
regulation of homeostatic process GO:0032844 182 0.013
cell fate determination involved in pattern specification GO:0060582 1 0.012
mapk cascade GO:0000165 281 0.012
digestive system development GO:0055123 200 0.012
sensory system development GO:0048880 3 0.012
membrane organization GO:0061024 245 0.012
cerebral cortex development GO:0021987 86 0.012
regulation of lymphocyte proliferation GO:0050670 117 0.012
response to oxidative stress GO:0006979 123 0.012
sequestering of metal ion GO:0051238 19 0.012
circadian rhythm GO:0007623 114 0.012
mrna metabolic process GO:0016071 84 0.012
negative regulation of leukocyte proliferation GO:0070664 46 0.012
negative regulation of cell fate specification GO:0009996 4 0.012
meiotic cell cycle process GO:1903046 77 0.012
inflammatory response GO:0006954 244 0.012
regulation of neural precursor cell proliferation GO:2000177 70 0.012
glycerolipid metabolic process GO:0046486 122 0.012
oogenesis GO:0048477 56 0.012
response to acid chemical GO:0001101 111 0.012
regulation of cellular response to stress GO:0080135 159 0.012
positive regulation of t cell activation GO:0050870 101 0.012
response to insulin GO:0032868 100 0.012
negative regulation of protein maturation GO:1903318 79 0.012
synapse assembly GO:0007416 56 0.012
lymphocyte proliferation GO:0046651 164 0.012
cellular nitrogen compound catabolic process GO:0044270 280 0.012
microtubule cytoskeleton organization GO:0000226 157 0.012
lung development GO:0030324 164 0.012
positive regulation of defense response GO:0031349 124 0.012
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.012
regulation of cell projection organization GO:0031344 206 0.012
maintenance of location GO:0051235 89 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.012
mesodermal cell migration GO:0008078 4 0.011
response to organonitrogen compound GO:0010243 246 0.011
rho protein signal transduction GO:0007266 32 0.011
negative regulation of proteolysis GO:0045861 74 0.011
regulation of muscle tissue development GO:1901861 97 0.011
cation transport GO:0006812 399 0.011
protein localization to organelle GO:0033365 185 0.011
neuron projection guidance GO:0097485 141 0.011
skeletal muscle cell differentiation GO:0035914 66 0.011
blastocyst development GO:0001824 80 0.011
hepaticobiliary system development GO:0061008 67 0.011
regulation of defense response GO:0031347 233 0.011
axonogenesis GO:0007409 274 0.011
positive regulation of protein modification process GO:0031401 299 0.011
b cell differentiation GO:0030183 78 0.011
regulation of response to wounding GO:1903034 189 0.011
oocyte construction GO:0007308 2 0.011
inorganic ion transmembrane transport GO:0098660 234 0.011
circadian regulation of gene expression GO:0032922 48 0.011
positive regulation of proteolysis GO:0045862 85 0.011
regulation of t cell differentiation GO:0045580 83 0.011
regulation of protein catabolic process GO:0042176 108 0.011
regulation of anatomical structure size GO:0090066 178 0.011
phagocytosis GO:0006909 66 0.011
positive regulation of cellular amine metabolic process GO:0033240 5 0.011
regulation of vesicle mediated transport GO:0060627 139 0.011
compound eye development GO:0048749 1 0.011
divalent inorganic cation transport GO:0072511 178 0.011
cellular response to organonitrogen compound GO:0071417 145 0.011
regulation of ras protein signal transduction GO:0046578 114 0.010
mesenchyme development GO:0060485 152 0.010
respiratory tube development GO:0030323 167 0.010
cell recognition GO:0008037 83 0.010
regulation of cell activation GO:0050865 289 0.010
cellular amine metabolic process GO:0044106 44 0.010
oocyte anterior posterior axis specification GO:0007314 2 0.010
actin filament based movement GO:0030048 23 0.010
peptidyl lysine modification GO:0018205 77 0.010
regulation of intracellular transport GO:0032386 159 0.010
sequestering of calcium ion GO:0051208 18 0.010
amine metabolic process GO:0009308 45 0.010
development of primary sexual characteristics GO:0045137 143 0.010
regulation of neuron differentiation GO:0045664 281 0.010
mrna processing GO:0006397 63 0.010
response to uv GO:0009411 44 0.010
negative regulation of cell cycle process GO:0010948 69 0.010
bone morphogenesis GO:0060349 78 0.010
rna splicing via transesterification reactions GO:0000375 43 0.010

Setd1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.024
disease of cellular proliferation DOID:14566 0 0.024
organ system cancer DOID:0050686 0 0.023
disease of metabolism DOID:0014667 0 0.020