Mus musculus

37 known processes

Wdhd1

WD repeat and HMG-box DNA binding protein 1

(Aliases: AND-1,D630024B06Rik,A630092E18)

Wdhd1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna repair GO:0006281 107 0.973
organelle fission GO:0048285 170 0.931
Worm
meiotic cell cycle GO:0051321 122 0.914
Worm
dna metabolic process GO:0006259 303 0.902
Fly
double strand break repair GO:0006302 48 0.826
cellular response to dna damage stimulus GO:0006974 207 0.758
dna recombination GO:0006310 92 0.705
microtubule cytoskeleton organization GO:0000226 157 0.683
centrosome organization GO:0051297 26 0.659
meiotic cell cycle process GO:1903046 77 0.655
Worm
mitotic cell cycle process GO:1903047 159 0.614
regulation of mitotic cell cycle phase transition GO:1901990 73 0.584
meiotic nuclear division GO:0007126 115 0.572
Worm
regulation of cell cycle process GO:0010564 160 0.562
nuclear division GO:0000280 158 0.550
Worm
recombinational repair GO:0000725 21 0.525
male meiosis i GO:0007141 16 0.522
mitotic sister chromatid segregation GO:0000070 14 0.510
male meiosis GO:0007140 37 0.490
dna dependent dna replication maintenance of fidelity GO:0045005 3 0.487
mitotic cell cycle GO:0000278 195 0.487
Fly
chromosome segregation GO:0007059 48 0.484
Worm
meiotic chromosome segregation GO:0045132 19 0.475
Worm
regulation of cell division GO:0051302 76 0.467
dna replication GO:0006260 52 0.463
Fly
cellular macromolecule catabolic process GO:0044265 206 0.453
regulation of mitotic cell cycle GO:0007346 126 0.445
negative regulation of cell cycle phase transition GO:1901988 48 0.434
regulation of cell cycle GO:0051726 281 0.431
double strand break repair via homologous recombination GO:0000724 21 0.417
gonad development GO:0008406 141 0.407
regulation of nuclear division GO:0051783 56 0.336
negative regulation of cellular component organization GO:0051129 194 0.332
regulation of organelle organization GO:0033043 289 0.323
regulation of mitosis GO:0007088 29 0.322
mitotic nuclear division GO:0007067 48 0.315
translesion synthesis GO:0019985 1 0.305
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.293
meiosis i GO:0007127 60 0.282
histone threonine phosphorylation GO:0035405 1 0.281
cell cycle checkpoint GO:0000075 47 0.281
mitotic sister chromatid cohesion GO:0007064 1 0.278
dna biosynthetic process GO:0071897 22 0.276
dna dependent dna replication GO:0006261 24 0.275
female meiosis chromosome segregation GO:0016321 1 0.266
cell division GO:0051301 120 0.255
macromolecule catabolic process GO:0009057 281 0.239
ribonucleoside catabolic process GO:0042454 206 0.234
negative regulation of mitotic cell cycle GO:0045930 58 0.234
negative regulation of cell cycle GO:0045786 123 0.233
sister chromatid segregation GO:0000819 20 0.224
regulation of cell cycle phase transition GO:1901987 77 0.224
microtubule organizing center organization GO:0031023 28 0.221
cellular protein catabolic process GO:0044257 155 0.214
ubiquitin dependent protein catabolic process GO:0006511 129 0.207
intrinsic apoptotic signaling pathway GO:0097193 132 0.195
negative regulation of nuclear division GO:0051784 19 0.189
microtubule based process GO:0007017 236 0.180
response to radiation GO:0009314 165 0.161
regulation of cell cycle g2 m phase transition GO:1902749 10 0.156
regulation of chromosome organization GO:0033044 83 0.152
development of primary sexual characteristics GO:0045137 143 0.150
protein catabolic process GO:0030163 221 0.147
nucleoside metabolic process GO:0009116 246 0.143
double strand break repair via nonhomologous end joining GO:0006303 10 0.140
nucleoside phosphate catabolic process GO:1901292 222 0.138
purine ribonucleotide metabolic process GO:0009150 290 0.135
positive regulation of cell cycle GO:0045787 92 0.128
centrosome cycle GO:0007098 23 0.126
cellular nitrogen compound catabolic process GO:0044270 280 0.125
reciprocal dna recombination GO:0035825 16 0.124
non recombinational repair GO:0000726 10 0.122
mitotic recombination GO:0006312 3 0.121
negative regulation of cell cycle process GO:0010948 69 0.114
dna endoreduplication GO:0042023 4 0.113
Fly
purine nucleotide metabolic process GO:0006163 302 0.109
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.107
cellular amino acid metabolic process GO:0006520 103 0.106
nucleoside triphosphate metabolic process GO:0009141 230 0.106
atp catabolic process GO:0006200 55 0.105
regulation of chromosome segregation GO:0051983 21 0.104
glycosyl compound metabolic process GO:1901657 246 0.102
purine nucleoside catabolic process GO:0006152 205 0.101
organic cyclic compound catabolic process GO:1901361 295 0.101
negative regulation of cell division GO:0051782 24 0.100
atp metabolic process GO:0046034 75 0.099
glycosyl compound catabolic process GO:1901658 206 0.098
negative regulation of mitosis GO:0045839 10 0.095
chiasma assembly GO:0051026 6 0.095
organophosphate catabolic process GO:0046434 232 0.092
nuclear dna replication GO:0033260 3 0.092
organonitrogen compound catabolic process GO:1901565 264 0.090
mitotic chromosome condensation GO:0007076 1 0.089
apoptotic signaling pathway GO:0097190 306 0.089
purine ribonucleoside metabolic process GO:0046128 241 0.088
nucleobase containing small molecule metabolic process GO:0055086 352 0.087
purine nucleotide catabolic process GO:0006195 211 0.080
germ cell development GO:0007281 185 0.079
chromatin organization GO:0006325 206 0.078
purine nucleoside triphosphate catabolic process GO:0009146 203 0.078
purine nucleoside triphosphate metabolic process GO:0009144 226 0.073
genitalia development GO:0048806 37 0.072
reciprocal meiotic recombination GO:0007131 16 0.071
negative regulation of organelle organization GO:0010639 90 0.071
heterocycle catabolic process GO:0046700 280 0.071
dna catabolic process GO:0006308 19 0.071
nucleoside triphosphate catabolic process GO:0009143 205 0.070
intra s dna damage checkpoint GO:0031573 4 0.070
membrane organization GO:0061024 245 0.068
purine nucleoside metabolic process GO:0042278 241 0.067
regulation of cellular catabolic process GO:0031329 242 0.065
nucleotide metabolic process GO:0009117 332 0.065
ribonucleoside triphosphate catabolic process GO:0009203 199 0.065
nucleoside monophosphate metabolic process GO:0009123 85 0.064
purine containing compound metabolic process GO:0072521 311 0.063
cellular response to abiotic stimulus GO:0071214 56 0.062
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.061
organelle assembly GO:0070925 177 0.060
purine ribonucleotide catabolic process GO:0009154 208 0.059
cellular response to organonitrogen compound GO:0071417 145 0.059
purine containing compound catabolic process GO:0072523 213 0.058
anatomical structure homeostasis GO:0060249 145 0.058
modification dependent protein catabolic process GO:0019941 133 0.055
ribonucleotide metabolic process GO:0009259 291 0.055
regulation of nuclear cell cycle dna replication GO:0033262 2 0.055
establishment of organelle localization GO:0051656 122 0.053
dna replication initiation GO:0006270 5 0.053
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.052
ribonucleoside triphosphate metabolic process GO:0009199 220 0.052
aromatic compound catabolic process GO:0019439 286 0.051
ribose phosphate metabolic process GO:0019693 291 0.051
regulation of protein catabolic process GO:0042176 108 0.050
response to light stimulus GO:0009416 135 0.049
ribonucleotide catabolic process GO:0009261 208 0.048
cellular ketone metabolic process GO:0042180 84 0.048
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.047
spindle organization GO:0007051 28 0.046
chromosome separation GO:0051304 14 0.046
response to organic cyclic compound GO:0014070 198 0.045
regulation of cellular amine metabolic process GO:0033238 20 0.045
carbohydrate derivative catabolic process GO:1901136 231 0.045
centrosome duplication GO:0051298 16 0.044
centriole assembly GO:0098534 6 0.043
positive regulation of apoptotic process GO:0043065 217 0.043
purine nucleoside monophosphate metabolic process GO:0009126 81 0.042
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 16 0.042
female meiotic division GO:0007143 21 0.042
sister chromatid cohesion GO:0007062 12 0.041
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.041
male gamete generation GO:0048232 285 0.040
ribonucleoside metabolic process GO:0009119 245 0.039
nucleoside monophosphate catabolic process GO:0009125 59 0.038
purine nucleoside monophosphate catabolic process GO:0009128 58 0.038
protein modification by small protein conjugation or removal GO:0070647 207 0.038
ribonucleoside monophosphate catabolic process GO:0009158 57 0.037
chromosome organization involved in meiosis GO:0070192 39 0.037
histone modification GO:0016570 159 0.036
inner cell mass cell proliferation GO:0001833 15 0.036
proteasomal protein catabolic process GO:0010498 98 0.035
negative regulation of protein metabolic process GO:0051248 282 0.035
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.035
metaphase plate congression GO:0051310 2 0.035
cellular response to ionizing radiation GO:0071479 11 0.035
nucleoside catabolic process GO:0009164 206 0.035
response to ionizing radiation GO:0010212 42 0.035
positive regulation of organelle organization GO:0010638 128 0.034
female gamete generation GO:0007292 74 0.033
positive regulation of mitotic cell cycle GO:0045931 41 0.033
dna integrity checkpoint GO:0031570 28 0.033
regulation of double strand break repair via homologous recombination GO:0010569 2 0.033
regulation of mitotic sister chromatid segregation GO:0033047 12 0.032
cellular response to organic cyclic compound GO:0071407 87 0.032
negative regulation of meiotic cell cycle phase transition GO:1901994 3 0.032
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.032
amine metabolic process GO:0009308 45 0.032
nucleoside phosphate metabolic process GO:0006753 338 0.031
maintenance of location GO:0051235 89 0.031
single fertilization GO:0007338 82 0.031
protein ubiquitination GO:0016567 171 0.031
regulation of proteasomal protein catabolic process GO:0061136 46 0.031
modification dependent macromolecule catabolic process GO:0043632 133 0.031
mitotic sister chromatid separation GO:0051306 9 0.031
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 15 0.030
positive regulation of cell death GO:0010942 224 0.030
dna unwinding involved in dna replication GO:0006268 5 0.030
organelle localization GO:0051640 179 0.030
regulation of centriole replication GO:0046599 1 0.030
peptidyl amino acid modification GO:0018193 336 0.030
cell fate commitment GO:0045165 210 0.029
gene silencing GO:0016458 38 0.029
metaphase anaphase transition of mitotic cell cycle GO:0007091 9 0.028
regulation of cellular amino acid metabolic process GO:0006521 5 0.028
negative regulation of cellular protein metabolic process GO:0032269 247 0.028
positive regulation of cell cycle process GO:0090068 61 0.028
negative regulation of dna dependent dna replication GO:2000104 1 0.028
regulation of exit from mitosis GO:0007096 1 0.028
oocyte maturation GO:0001556 18 0.028
cellular amine metabolic process GO:0044106 44 0.027
lateral inhibition GO:0046331 1 0.027
positive regulation of cellular amine metabolic process GO:0033240 5 0.027
dna geometric change GO:0032392 7 0.027
regulation of meiosis i GO:0060631 7 0.027
protein maturation GO:0051604 176 0.026
synapsis GO:0007129 34 0.026
spindle assembly involved in female meiosis GO:0007056 3 0.026
replication fork protection GO:0048478 1 0.025
positive regulation of hydrolase activity GO:0051345 148 0.025
rna dependent dna replication GO:0006278 3 0.025
regulation of dna replication GO:0006275 17 0.025
negative regulation of proteolysis GO:0045861 74 0.025
somatic diversification of immune receptors via somatic mutation GO:0002566 8 0.025
macromolecule methylation GO:0043414 120 0.024
positive regulation of cell cycle phase transition GO:1901989 17 0.024
response to purine containing compound GO:0014074 28 0.024
regulation of circadian rhythm GO:0042752 58 0.024
cell cycle g2 m phase transition GO:0044839 20 0.024
response to organonitrogen compound GO:0010243 246 0.024
positive regulation of programmed cell death GO:0043068 218 0.024
regulation of dna recombination GO:0000018 34 0.023
regulation of cellular protein catabolic process GO:1903362 61 0.023
regulation of cytoskeleton organization GO:0051493 122 0.023
positive regulation of meiotic cell cycle GO:0051446 15 0.023
regulation of protein kinase activity GO:0045859 232 0.023
regulation of hydrolase activity GO:0051336 246 0.022
regulation of histone modification GO:0031056 56 0.022
attachment of spindle microtubules to kinetochore GO:0008608 4 0.022
dna catabolic process exonucleolytic GO:0000738 3 0.022
spindle assembly involved in mitosis GO:0090307 4 0.022
cellular response to radiation GO:0071478 28 0.022
regulation of transcription by chromatin organization GO:0034401 0 0.022
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.021
dna catabolic process endonucleolytic GO:0000737 15 0.021
regulation of proteolysis GO:0030162 164 0.021
protein acylation GO:0043543 64 0.021
regulation of metaphase anaphase transition of cell cycle GO:1902099 9 0.021
protein modification by small protein conjugation GO:0032446 187 0.021
negative regulation of gene expression epigenetic GO:0045814 15 0.021
receptor mediated endocytosis GO:0006898 51 0.021
stem cell fate determination GO:0048867 2 0.020
leukocyte proliferation GO:0070661 172 0.020
regulation of sister chromatid cohesion GO:0007063 5 0.020
dna damage checkpoint GO:0000077 26 0.020
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.020
negative regulation of histone h3 k9 methylation GO:0051573 4 0.019
mitotic centrosome separation GO:0007100 4 0.019
regulation of cellular ketone metabolic process GO:0010565 66 0.019
positive regulation of t cell activation GO:0050870 101 0.019
alpha beta t cell differentiation GO:0046632 69 0.019
negative regulation of molecular function GO:0044092 258 0.019
dna duplex unwinding GO:0032508 7 0.019
spermatogenesis GO:0007283 284 0.019
response to uv GO:0009411 44 0.019
protein processing GO:0016485 163 0.019
negative regulation of mitotic sister chromatid segregation GO:0033048 7 0.019
methylation GO:0032259 134 0.019
negative regulation of protein catabolic process GO:0042177 36 0.019
negative regulation of sister chromatid segregation GO:0033046 7 0.018
chromatin assembly or disassembly GO:0006333 16 0.018
histone h3 acetylation GO:0043966 14 0.018
negative regulation of protein processing GO:0010955 79 0.018
mitotic cell cycle checkpoint GO:0007093 31 0.018
oogenesis GO:0048477 56 0.018
meiosis ii GO:0007135 7 0.018
ras protein signal transduction GO:0007265 77 0.018
covalent chromatin modification GO:0016569 163 0.018
striated muscle myosin thick filament assembly GO:0071688 1 0.017
dna replication checkpoint GO:0000076 2 0.017
chromatin remodeling at centromere GO:0031055 2 0.017
locomotory behavior GO:0007626 195 0.017
negative regulation of mitotic metaphase anaphase transition GO:0045841 7 0.017
cytokinesis GO:0000910 17 0.017
regulation of mitotic sister chromatid separation GO:0010965 12 0.017
endocytosis GO:0006897 168 0.017
regulation of transferase activity GO:0051338 263 0.017
posttranscriptional gene silencing GO:0016441 10 0.017
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.017
myosin filament assembly GO:0031034 2 0.017
multicellular organismal homeostasis GO:0048871 164 0.016
response to camptothecin GO:1901563 1 0.016
regulation of t cell proliferation GO:0042129 92 0.016
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.016
regulation of binding GO:0051098 111 0.016
regulation of protein maturation GO:1903317 96 0.016
negative regulation of thymocyte apoptotic process GO:0070244 8 0.016
histone acetylation GO:0016573 41 0.016
regulation of cellular response to stress GO:0080135 159 0.016
posttranscriptional regulation of gene expression GO:0010608 155 0.016
cell cycle g1 s phase transition GO:0044843 57 0.016
gland development GO:0048732 330 0.016
nitrogen compound transport GO:0071705 271 0.016
intracellular protein transport GO:0006886 204 0.016
regulation of protein localization GO:0032880 231 0.015
negative regulation of protein modification process GO:0031400 163 0.015
negative regulation of chromosome organization GO:2001251 30 0.015
purine ribonucleoside catabolic process GO:0046130 205 0.015
nucleotide catabolic process GO:0009166 217 0.014
cell type specific apoptotic process GO:0097285 268 0.014
negative regulation of transferase activity GO:0051348 85 0.014
regulation of g2 m transition of mitotic cell cycle GO:0010389 10 0.014
neuroblast differentiation GO:0014016 2 0.014
response to alkaloid GO:0043279 34 0.014
negative regulation of mitotic sister chromatid separation GO:2000816 7 0.014
regulation of cellular component biogenesis GO:0044087 181 0.014
ribonucleoside monophosphate metabolic process GO:0009161 80 0.014
blastocyst development GO:0001824 80 0.014
homeostasis of number of cells GO:0048872 210 0.014
mitotic g2 dna damage checkpoint GO:0007095 8 0.014
mrna processing GO:0006397 63 0.014
base excision repair gap filling GO:0006287 3 0.013
positive regulation of cellular component biogenesis GO:0044089 94 0.013
body morphogenesis GO:0010171 45 0.013
cell adhesion GO:0007155 329 0.013
regulation of dna dependent dna replication GO:0090329 8 0.013
regulation of thymocyte apoptotic process GO:0070243 14 0.013
cell activation involved in immune response GO:0002263 126 0.013
positive regulation of protein modification process GO:0031401 299 0.013
lymphocyte mediated immunity GO:0002449 139 0.013
circadian rhythm GO:0007623 114 0.012
negative regulation of transcription involved in g1 s transition of mitotic cell cycle GO:0071930 1 0.012
regulation of purine nucleotide metabolic process GO:1900542 169 0.012
regulation of kinase activity GO:0043549 249 0.012
postreplication repair GO:0006301 5 0.012
regulation of microtubule based process GO:0032886 52 0.012
small gtpase mediated signal transduction GO:0007264 97 0.012
internal peptidyl lysine acetylation GO:0018393 42 0.012
multicellular organism growth GO:0035264 161 0.012
folic acid containing compound metabolic process GO:0006760 3 0.012
cation transport GO:0006812 399 0.012
intracellular mrna localization GO:0008298 4 0.012
internal protein amino acid acetylation GO:0006475 42 0.012
peptidyl lysine modification GO:0018205 77 0.012
placenta development GO:0001890 140 0.012
negative regulation of cellular protein catabolic process GO:1903363 22 0.012
heterochromatin organization GO:0070828 4 0.011
negative regulation of metaphase anaphase transition of cell cycle GO:1902100 8 0.011
chromatin modification GO:0016568 187 0.011
neuroblast fate determination GO:0007400 1 0.011
regulation of chromatin modification GO:1903308 57 0.011
antimicrobial peptide biosynthetic process GO:0002777 2 0.011
regulation of leukocyte proliferation GO:0070663 121 0.011
histone h3 k9 methylation GO:0051567 17 0.011
protein import into nucleus GO:0006606 95 0.011
cellular response to cytokine stimulus GO:0071345 189 0.011
histone h3 k9 trimethylation GO:0036124 6 0.011
regulation of protein processing GO:0070613 96 0.011
negative regulation of ubiquitin protein transferase activity GO:0051444 3 0.011
positive regulation of histone h3 k9 methylation GO:0051574 4 0.011
negative regulation of cellular catabolic process GO:0031330 47 0.011
gpi anchor metabolic process GO:0006505 7 0.011
astral microtubule organization GO:0030953 3 0.011
positive regulation of lymphocyte activation GO:0051251 140 0.011
regulation of purine nucleotide catabolic process GO:0033121 122 0.011
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 1 0.011
regulation of chromatin organization GO:1902275 57 0.011
dna conformation change GO:0071103 37 0.011
replication fork processing GO:0031297 1 0.010
lymphocyte proliferation GO:0046651 164 0.010
meiotic dna repair synthesis GO:0000711 4 0.010
chromatin mediated maintenance of transcription GO:0048096 2 0.010
thymocyte apoptotic process GO:0070242 19 0.010
leukocyte differentiation GO:0002521 342 0.010
lipid biosynthetic process GO:0008610 179 0.010
positive regulation of cellular catabolic process GO:0031331 148 0.010
rhythmic process GO:0048511 174 0.010
positive regulation of meiosis i GO:0060903 5 0.010
chromatin silencing GO:0006342 15 0.010

Wdhd1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.112
cancer DOID:162 0 0.086
organ system cancer DOID:0050686 0 0.045
immune system disease DOID:2914 0 0.038
aplastic anemia DOID:12449 0 0.038
disease of anatomical entity DOID:7 0 0.038
bone marrow disease DOID:4961 0 0.038
anemia DOID:2355 0 0.038
hematopoietic system disease DOID:74 0 0.038
thoracic cancer DOID:5093 0 0.038
breast cancer DOID:1612 0 0.025
male reproductive organ cancer DOID:3856 0 0.018
reproductive organ cancer DOID:193 0 0.018
prostate cancer DOID:10283 0 0.016
urinary system cancer DOID:3996 0 0.013