Mus musculus

0 known processes

Otud4

OTU domain containing 4

(Aliases: 4930431L18Rik,mKIAA1046,AI449692,D8Ertd69e)

Otud4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rna 3 end processing GO:0031123 20 0.369
regulation of cell cycle GO:0051726 281 0.339
regulation of cell cycle process GO:0010564 160 0.246
macromolecule catabolic process GO:0009057 281 0.231
cellular macromolecule catabolic process GO:0044265 206 0.211
dendrite development GO:0016358 115 0.180
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.177
cellular protein catabolic process GO:0044257 155 0.173
negative regulation of protein metabolic process GO:0051248 282 0.166
negative regulation of cellular amine metabolic process GO:0033239 1 0.146
modification dependent macromolecule catabolic process GO:0043632 133 0.142
compound eye development GO:0048749 1 0.136
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.117
nuclear division GO:0000280 158 0.113
regulation of organelle organization GO:0033043 289 0.108
protein modification by small protein conjugation GO:0032446 187 0.100
protein modification by small protein conjugation or removal GO:0070647 207 0.100
mitotic cell cycle GO:0000278 195 0.083
cellular amine metabolic process GO:0044106 44 0.083
meiotic nuclear division GO:0007126 115 0.082
protein ubiquitination GO:0016567 171 0.078
protein modification by small protein removal GO:0070646 21 0.077
positive regulation of lipid storage GO:0010884 10 0.077
mitotic cell cycle process GO:1903047 159 0.076
organelle assembly GO:0070925 177 0.075
covalent chromatin modification GO:0016569 163 0.073
regulation of nuclear division GO:0051783 56 0.072
stem cell maintenance GO:0019827 130 0.071
germ cell development GO:0007281 185 0.071
amine metabolic process GO:0009308 45 0.071
cellular response to dna damage stimulus GO:0006974 207 0.070
regulation of cellular ketone metabolic process GO:0010565 66 0.069
negative regulation of cellular protein metabolic process GO:0032269 247 0.064
cell division GO:0051301 120 0.062
regulation of cell activation GO:0050865 289 0.061
positive regulation of mrna 3 end processing GO:0031442 5 0.060
cellular ketone metabolic process GO:0042180 84 0.059
histone modification GO:0016570 159 0.059
lateral inhibition GO:0046331 1 0.058
maintenance of location GO:0051235 89 0.058
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.058
rna processing GO:0006396 105 0.057
negative regulation of cell cycle phase transition GO:1901988 48 0.056
peptidyl amino acid modification GO:0018193 336 0.056
female gamete generation GO:0007292 74 0.055
rna polyadenylation GO:0043631 6 0.054
multicellular organismal macromolecule catabolic process GO:0044266 1 0.053
rhythmic process GO:0048511 174 0.053
regulation of lymphocyte activation GO:0051249 240 0.052
ubiquitin dependent protein catabolic process GO:0006511 129 0.052
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.052
regulation of mitotic cell cycle phase transition GO:1901990 73 0.049
organelle localization GO:0051640 179 0.049
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.049
regulation of apoptotic signaling pathway GO:2001233 197 0.049
male gamete generation GO:0048232 285 0.048
spermatogenesis GO:0007283 284 0.047
establishment of organelle localization GO:0051656 122 0.047
chromatin organization GO:0006325 206 0.045
chromatin modification GO:0016568 187 0.044
synaptic transmission GO:0007268 329 0.043
microtubule cytoskeleton organization GO:0000226 157 0.042
protein localization to nucleus GO:0034504 121 0.042
metaphase plate congression GO:0051310 2 0.042
regulation of cellular amino acid metabolic process GO:0006521 5 0.041
ras protein signal transduction GO:0007265 77 0.041
sister chromatid segregation GO:0000819 20 0.039
organelle fission GO:0048285 170 0.038
meiotic cell cycle GO:0051321 122 0.038
cell fate commitment GO:0045165 210 0.037
aromatic compound catabolic process GO:0019439 286 0.037
regulation of defense response GO:0031347 233 0.036
regulation of mitotic cell cycle GO:0007346 126 0.036
meiotic cell cycle process GO:1903046 77 0.035
regulation of cellular catabolic process GO:0031329 242 0.035
cellular response to insulin stimulus GO:0032869 78 0.034
regionalization GO:0003002 337 0.034
negative regulation of mitotic cell cycle GO:0045930 58 0.033
regulation of chromatin organization GO:1902275 57 0.032
mitotic chromosome condensation GO:0007076 1 0.032
cellular response to organonitrogen compound GO:0071417 145 0.032
response to lipopolysaccharide GO:0032496 128 0.032
positive regulation of cell cycle process GO:0090068 61 0.031
regulation of protein transport GO:0051223 163 0.031
regulation of meiotic cell cycle GO:0051445 34 0.030
dendritic spine development GO:0060996 30 0.030
negative regulation of dna replication GO:0008156 4 0.030
actin cytoskeleton organization GO:0030036 220 0.030
ossification GO:0001503 216 0.030
b cell activation GO:0042113 161 0.030
positive regulation of protein localization to nucleus GO:1900182 30 0.029
cellularization GO:0007349 1 0.029
regulation of proteolysis GO:0030162 164 0.029
positive regulation of apoptotic process GO:0043065 217 0.029
multicellular organismal protein metabolic process GO:0044268 2 0.029
response to hypoxia GO:0001666 58 0.029
modification dependent protein catabolic process GO:0019941 133 0.029
neural precursor cell proliferation GO:0061351 121 0.029
regulation of cellular amine metabolic process GO:0033238 20 0.028
circulatory system process GO:0003013 197 0.027
spermatid differentiation GO:0048515 115 0.027
regulation of cellular component biogenesis GO:0044087 181 0.027
mrna 3 end processing GO:0031124 16 0.027
stem cell differentiation GO:0048863 268 0.026
negative regulation of cell proliferation GO:0008285 296 0.026
myeloid cell differentiation GO:0030099 233 0.026
cellular nitrogen compound catabolic process GO:0044270 280 0.026
mitotic nuclear division GO:0007067 48 0.026
response to oxidative stress GO:0006979 123 0.026
termination of rna polymerase i transcription GO:0006363 2 0.025
apoptotic signaling pathway GO:0097190 306 0.025
regulation of protein catabolic process GO:0042176 108 0.025
regulation of cell cycle phase transition GO:1901987 77 0.024
proteasomal protein catabolic process GO:0010498 98 0.024
regulation of cell division GO:0051302 76 0.024
protein digestion GO:0044256 1 0.024
microtubule nucleation GO:0007020 2 0.024
posttranscriptional regulation of gene expression GO:0010608 155 0.024
cellular response to peptide GO:1901653 92 0.024
protein localization to organelle GO:0033365 185 0.024
regulation of protein complex assembly GO:0043254 83 0.023
cajal body organization GO:0030576 1 0.023
dna integrity checkpoint GO:0031570 28 0.023
oocyte axis specification GO:0007309 2 0.023
cation transport GO:0006812 399 0.023
oocyte construction GO:0007308 2 0.023
signal transduction by p53 class mediator GO:0072331 51 0.023
negative regulation of phosphate metabolic process GO:0045936 184 0.022
innate immune response GO:0045087 157 0.022
multicellular organismal protein catabolic process GO:0044254 1 0.022
positive regulation of programmed cell death GO:0043068 218 0.022
gonad development GO:0008406 141 0.022
stem cell development GO:0048864 219 0.022
regulation of neuron differentiation GO:0045664 281 0.021
cellular response to oxidative stress GO:0034599 76 0.021
positive regulation of intrinsic apoptotic signaling pathway GO:2001244 25 0.021
leukocyte differentiation GO:0002521 342 0.021
cellular response to peptide hormone stimulus GO:0071375 92 0.020
rna interference GO:0016246 2 0.020
regulation of protein targeting GO:1903533 61 0.020
protein catabolic process GO:0030163 221 0.020
cytoplasmic transport GO:0016482 234 0.019
regulation of establishment of protein localization GO:0070201 181 0.019
chromosome segregation GO:0007059 48 0.019
response to organonitrogen compound GO:0010243 246 0.019
positive regulation of protein transport GO:0051222 93 0.019
lipid localization GO:0010876 126 0.019
circadian rhythm GO:0007623 114 0.019
cellular amino acid metabolic process GO:0006520 103 0.019
cation transmembrane transport GO:0098655 266 0.019
protein polyubiquitination GO:0000209 33 0.018
negative regulation of protein modification process GO:0031400 163 0.018
cellular response to hormone stimulus GO:0032870 150 0.018
mrna metabolic process GO:0016071 84 0.018
translation GO:0006412 93 0.018
spinal cord oligodendrocyte cell differentiation GO:0021529 3 0.018
mrna localization resulting in posttranscriptional regulation of gene expression GO:0010609 2 0.018
cytokine production GO:0001816 319 0.018
mrna polyadenylation GO:0006378 5 0.017
negative regulation of immune system process GO:0002683 209 0.017
membrane organization GO:0061024 245 0.017
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.017
protein processing GO:0016485 163 0.017
regulation of dna dependent dna replication GO:0090329 8 0.017
purine containing compound metabolic process GO:0072521 311 0.017
establishment of rna localization GO:0051236 18 0.017
positive regulation of apoptotic signaling pathway GO:2001235 95 0.017
positive regulation of cell cycle GO:0045787 92 0.017
heterocycle catabolic process GO:0046700 280 0.017
negative regulation of cell cycle GO:0045786 123 0.017
nucleus organization GO:0006997 45 0.016
learning or memory GO:0007611 148 0.016
ribonucleoprotein complex subunit organization GO:0071826 28 0.016
positive regulation of mitotic sister chromatid separation GO:1901970 2 0.016
nucleoside triphosphate metabolic process GO:0009141 230 0.016
positive regulation of organelle organization GO:0010638 128 0.016
organic hydroxy compound metabolic process GO:1901615 203 0.016
fertilization GO:0009566 127 0.016
mrna transport GO:0051028 13 0.016
positive regulation of proteolysis GO:0045862 85 0.015
cellular response to lipid GO:0071396 145 0.015
regulation of protein stability GO:0031647 52 0.015
termination of rna polymerase ii transcription GO:0006369 1 0.015
morphogenesis of a branching structure GO:0001763 203 0.015
embryonic placenta development GO:0001892 98 0.015
regulation of t cell activation GO:0050863 170 0.015
positive regulation of cell death GO:0010942 224 0.015
dna metabolic process GO:0006259 303 0.015
regulation of cellular protein catabolic process GO:1903362 61 0.015
negative regulation of translation GO:0017148 22 0.015
cardiac muscle cell contraction GO:0086003 7 0.015
cellular homeostasis GO:0019725 240 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.015
establishment of meiotic spindle orientation GO:0051296 1 0.015
regulation of erbb signaling pathway GO:1901184 16 0.015
positive regulation of transforming growth factor beta2 production GO:0032915 2 0.015
response to organic cyclic compound GO:0014070 198 0.015
nitrogen compound transport GO:0071705 271 0.014
protein deacylation GO:0035601 36 0.014
regulation of cytoskeleton organization GO:0051493 122 0.014
intracellular protein transport GO:0006886 204 0.014
nuclear transport GO:0051169 139 0.014
regulation of epithelial cell proliferation GO:0050678 141 0.014
organic cyclic compound catabolic process GO:1901361 295 0.014
peptidyl threonine phosphorylation GO:0018107 31 0.014
regulation of chromosome organization GO:0033044 83 0.014
homeostasis of number of cells GO:0048872 210 0.014
ubiquitin dependent smad protein catabolic process GO:0030579 2 0.014
regulation of system process GO:0044057 200 0.014
regulation of transcription by chromatin organization GO:0034401 0 0.014
mitochondrion organization GO:0007005 134 0.014
erbb signaling pathway GO:0038127 32 0.013
mitotic sister chromatid segregation GO:0000070 14 0.013
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 25 0.013
bmp signaling pathway GO:0030509 93 0.013
myeloid leukocyte activation GO:0002274 83 0.013
protein autophosphorylation GO:0046777 61 0.013
negative regulation of intracellular signal transduction GO:1902532 167 0.013
negative regulation of lymphocyte activation GO:0051250 91 0.013
phagocytosis GO:0006909 66 0.013
negative regulation of cellular component organization GO:0051129 194 0.013
skeletal system development GO:0001501 356 0.013
regulation of response to wounding GO:1903034 189 0.013
oxidation reduction process GO:0055114 342 0.013
cell cycle checkpoint GO:0000075 47 0.012
cell growth GO:0016049 130 0.012
positive regulation of mrna processing GO:0050685 16 0.012
negative regulation of nervous system development GO:0051961 156 0.012
t cell activation GO:0042110 289 0.012
memory GO:0007613 58 0.012
regulation of innate immune response GO:0045088 91 0.012
synapse organization GO:0050808 125 0.012
cellular response to molecule of bacterial origin GO:0071219 83 0.012
multi multicellular organism process GO:0044706 109 0.012
negative regulation of organelle organization GO:0010639 90 0.012
regulation of mitosis GO:0007088 29 0.012
regulation of cell projection organization GO:0031344 206 0.012
cellular protein complex assembly GO:0043623 116 0.012
dna damage checkpoint GO:0000077 26 0.012
cell type specific apoptotic process GO:0097285 268 0.012
blood circulation GO:0008015 195 0.012
peptidyl threonine modification GO:0018210 31 0.012
regulation of chromatin modification GO:1903308 57 0.012
b cell proliferation GO:0042100 53 0.012
regulation of rna splicing GO:0043484 37 0.012
regulation of cellular response to stress GO:0080135 159 0.012
epidermal growth factor receptor signaling pathway GO:0007173 28 0.012
protein acylation GO:0043543 64 0.012
male courtship behavior GO:0008049 2 0.012
response to insulin GO:0032868 100 0.012
sensory perception GO:0007600 245 0.012
defense response to other organism GO:0098542 197 0.011
leukocyte proliferation GO:0070661 172 0.011
positive regulation of nervous system development GO:0051962 221 0.011
neural crest formation GO:0014029 2 0.011
response to molecule of bacterial origin GO:0002237 143 0.011
negative regulation of phosphorus metabolic process GO:0010563 184 0.011
inorganic ion transmembrane transport GO:0098660 234 0.011
positive regulation of protein modification process GO:0031401 299 0.011
regulation of b cell activation GO:0050864 81 0.011
regulation of nucleocytoplasmic transport GO:0046822 73 0.011
positive regulation of intracellular transport GO:0032388 70 0.011
inorganic cation transmembrane transport GO:0098662 207 0.011
cell adhesion GO:0007155 329 0.011
negative regulation of synapse assembly GO:0051964 3 0.011
neuron projection extension GO:1990138 64 0.011
regulation of synapse assembly GO:0051963 29 0.011
negative regulation of cell cycle process GO:0010948 69 0.011
epidermis development GO:0008544 187 0.011
multicellular organism growth GO:0035264 161 0.011
protein polymerization GO:0051258 57 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.011
regulation of intracellular transport GO:0032386 159 0.011
regulation of protein localization to nucleus GO:1900180 60 0.011
divalent inorganic cation transport GO:0072511 178 0.011
nucleoside metabolic process GO:0009116 246 0.011
negative regulation of cell development GO:0010721 169 0.011
microtubule based process GO:0007017 236 0.010
establishment of protein localization to organelle GO:0072594 118 0.010
negative regulation of protein phosphorylation GO:0001933 126 0.010
spliceosomal complex disassembly GO:0000390 1 0.010
positive regulation of growth GO:0045927 104 0.010
developmental growth involved in morphogenesis GO:0060560 138 0.010
development of primary female sexual characteristics GO:0046545 73 0.010

Otud4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 0 0.039
disease of anatomical entity DOID:7 0 0.039
neurodegenerative disease DOID:1289 0 0.039
nervous system disease DOID:863 0 0.039
endocrine gland cancer DOID:170 0 0.016
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
organ system cancer DOID:0050686 0 0.016
disease of mental health DOID:150 0 0.011