Mus musculus

96 known processes

Eef2

eukaryotic translation elongation factor 2

(Aliases: Ef-2,MGC98463)

Eef2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nucleotide metabolic process GO:0009117 332 0.200
purine nucleotide metabolic process GO:0006163 302 0.179
nucleobase containing small molecule metabolic process GO:0055086 352 0.170
purine containing compound metabolic process GO:0072521 311 0.160
glycosyl compound metabolic process GO:1901657 246 0.141
organophosphate catabolic process GO:0046434 232 0.138
purine ribonucleoside catabolic process GO:0046130 205 0.137
nucleoside phosphate metabolic process GO:0006753 338 0.126
cellular nitrogen compound catabolic process GO:0044270 280 0.122
regulation of cellular catabolic process GO:0031329 242 0.122
nucleoside metabolic process GO:0009116 246 0.117
nucleoside triphosphate catabolic process GO:0009143 205 0.115
ribonucleotide catabolic process GO:0009261 208 0.109
purine nucleoside triphosphate catabolic process GO:0009146 203 0.108
nucleotide catabolic process GO:0009166 217 0.102
macromolecule catabolic process GO:0009057 281 0.100
purine ribonucleoside metabolic process GO:0046128 241 0.096
purine containing compound catabolic process GO:0072523 213 0.095
organic cyclic compound catabolic process GO:1901361 295 0.095
proteasomal protein catabolic process GO:0010498 98 0.094
purine ribonucleotide metabolic process GO:0009150 290 0.089
posttranscriptional regulation of gene expression GO:0010608 155 0.084
Human
ribonucleotide metabolic process GO:0009259 291 0.077
endomembrane system organization GO:0010256 147 0.076
modification dependent macromolecule catabolic process GO:0043632 133 0.074
cellular amine metabolic process GO:0044106 44 0.074
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.070
nucleoside triphosphate metabolic process GO:0009141 230 0.070
ribose phosphate metabolic process GO:0019693 291 0.070
cellular amino acid metabolic process GO:0006520 103 0.070
response to oxidative stress GO:0006979 123 0.069
protein catabolic process GO:0030163 221 0.067
regulation of cellular amino acid metabolic process GO:0006521 5 0.063
negative regulation of cellular amine metabolic process GO:0033239 1 0.063
purine nucleotide catabolic process GO:0006195 211 0.063
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.062
purine nucleoside metabolic process GO:0042278 241 0.062
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.061
ubiquitin dependent protein catabolic process GO:0006511 129 0.060
ribonucleoside catabolic process GO:0042454 206 0.060
translation GO:0006412 93 0.058
cellular protein catabolic process GO:0044257 155 0.058
generation of precursor metabolites and energy GO:0006091 103 0.056
aromatic compound catabolic process GO:0019439 286 0.056
ribonucleoside triphosphate catabolic process GO:0009203 199 0.056
heterocycle catabolic process GO:0046700 280 0.055
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.054
carbohydrate derivative catabolic process GO:1901136 231 0.054
carbohydrate metabolic process GO:0005975 230 0.053
negative regulation of phagocytosis GO:0050765 4 0.052
nucleoside catabolic process GO:0009164 206 0.052
regulation of cellular amine metabolic process GO:0033238 20 0.051
cellular ketone metabolic process GO:0042180 84 0.050
cellular homeostasis GO:0019725 240 0.049
regulation of cellular ketone metabolic process GO:0010565 66 0.049
purine nucleoside triphosphate metabolic process GO:0009144 226 0.048
wnt signaling pathway GO:0016055 188 0.048
nucleoside phosphate catabolic process GO:1901292 222 0.047
cellular response to interleukin 4 GO:0071353 21 0.047
spermatogenesis GO:0007283 284 0.046
purine nucleoside catabolic process GO:0006152 205 0.045
amine metabolic process GO:0009308 45 0.045
membrane organization GO:0061024 245 0.045
locomotory behavior GO:0007626 195 0.044
ribonucleoside metabolic process GO:0009119 245 0.043
multicellular organismal signaling GO:0035637 91 0.042
dna metabolic process GO:0006259 303 0.042
purine ribonucleotide catabolic process GO:0009154 208 0.041
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.041
regulation of protein kinase activity GO:0045859 232 0.040
ribonucleoside triphosphate metabolic process GO:0009199 220 0.040
renal system development GO:0072001 225 0.040
organonitrogen compound catabolic process GO:1901565 264 0.040
guanosine containing compound metabolic process GO:1901068 144 0.040
oxidation reduction process GO:0055114 342 0.039
cytoplasmic transport GO:0016482 234 0.039
camera type eye development GO:0043010 266 0.039
male gamete generation GO:0048232 285 0.038
protein ubiquitination GO:0016567 171 0.037
regulation of protein localization GO:0032880 231 0.037
regulation of nucleotide metabolic process GO:0006140 169 0.037
protein modification by small protein conjugation or removal GO:0070647 207 0.036
multicellular organism growth GO:0035264 161 0.035
modification dependent protein catabolic process GO:0019941 133 0.034
protein modification by small protein conjugation GO:0032446 187 0.034
cellular response to cytokine stimulus GO:0071345 189 0.034
glycosyl compound catabolic process GO:1901658 206 0.034
negative regulation of cellular protein metabolic process GO:0032269 247 0.033
regulation of cell motility GO:2000145 236 0.033
cellular carbohydrate metabolic process GO:0044262 119 0.033
stem cell development GO:0048864 219 0.033
cellular glucan metabolic process GO:0006073 32 0.032
multi multicellular organism process GO:0044706 109 0.032
regulation of nucleoside metabolic process GO:0009118 130 0.032
g protein coupled receptor signaling pathway GO:0007186 243 0.032
regulation of membrane potential GO:0042391 192 0.032
regulation of homeostatic process GO:0032844 182 0.031
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.031
energy derivation by oxidation of organic compounds GO:0015980 77 0.031
cellular component assembly involved in morphogenesis GO:0010927 139 0.030
gtp metabolic process GO:0046039 144 0.030
translational elongation GO:0006414 12 0.030
germ cell development GO:0007281 185 0.029
kidney development GO:0001822 213 0.029
carbohydrate biosynthetic process GO:0016051 74 0.028
regulation of purine nucleotide metabolic process GO:1900542 169 0.028
translational initiation GO:0006413 24 0.028
meiotic cell cycle GO:0051321 122 0.027
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 31 0.027
gonad development GO:0008406 141 0.027
protein localization to membrane GO:0072657 108 0.027
glucose homeostasis GO:0042593 128 0.027
regulation of hydrolase activity GO:0051336 246 0.026
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.026
peptidyl amino acid modification GO:0018193 336 0.025
transmission of nerve impulse GO:0019226 76 0.025
monosaccharide metabolic process GO:0005996 106 0.025
regulation of establishment of protein localization GO:0070201 181 0.025
angiogenesis GO:0001525 201 0.025
intracellular protein transport GO:0006886 204 0.025
cell adhesion GO:0007155 329 0.024
negative regulation of protein phosphorylation GO:0001933 126 0.024
microtubule cytoskeleton organization GO:0000226 157 0.023
Fly
digestive tract morphogenesis GO:0048546 147 0.023
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.023
spermatid differentiation GO:0048515 115 0.023
positive regulation of cell death GO:0010942 224 0.023
regulation of cell migration GO:0030334 219 0.022
positive regulation of cellular amine metabolic process GO:0033240 5 0.022
cell type specific apoptotic process GO:0097285 268 0.022
development of primary sexual characteristics GO:0045137 143 0.022
blood vessel morphogenesis GO:0048514 285 0.022
histone modification GO:0016570 159 0.022
cellular chemical homeostasis GO:0055082 215 0.022
negative regulation of protein modification process GO:0031400 163 0.022
regionalization GO:0003002 337 0.022
protein maturation GO:0051604 176 0.022
establishment or maintenance of cell polarity GO:0007163 86 0.021
positive regulation of gtp catabolic process GO:0033126 85 0.021
regulation of cellular protein catabolic process GO:1903362 61 0.021
urogenital system development GO:0001655 261 0.021
regulation of transferase activity GO:0051338 263 0.021
hexose metabolic process GO:0019318 98 0.021
cellular response to nutrient levels GO:0031669 64 0.021
homeostasis of number of cells GO:0048872 210 0.021
positive regulation of nucleotide metabolic process GO:0045981 114 0.020
cellular response to dna damage stimulus GO:0006974 207 0.020
positive regulation of protein modification process GO:0031401 299 0.020
dephosphorylation GO:0016311 129 0.020
regulation of proteasomal protein catabolic process GO:0061136 46 0.020
action potential GO:0001508 78 0.020
dna repair GO:0006281 107 0.020
organonitrogen compound biosynthetic process GO:1901566 192 0.020
positive regulation of nucleotide catabolic process GO:0030813 88 0.020
sensory perception GO:0007600 245 0.020
regulation of kinase activity GO:0043549 249 0.019
establishment of protein localization to organelle GO:0072594 118 0.019
endocytosis GO:0006897 168 0.019
negative regulation of molecular function GO:0044092 258 0.019
stem cell differentiation GO:0048863 268 0.019
divalent inorganic cation homeostasis GO:0072507 138 0.019
cellular response to growth factor stimulus GO:0071363 197 0.019
regulation of proteolysis GO:0030162 164 0.019
negative regulation of phosphorylation GO:0042326 166 0.019
negative regulation of phosphate metabolic process GO:0045936 184 0.019
cellular response to oxidative stress GO:0034599 76 0.019
positive regulation of cellular protein catabolic process GO:1903364 34 0.019
regulation of protein catabolic process GO:0042176 108 0.019
nuclear transport GO:0051169 139 0.018
negative regulation of intracellular signal transduction GO:1902532 167 0.018
plasma membrane organization GO:0007009 90 0.018
protein localization to plasma membrane GO:0072659 57 0.018
gland development GO:0048732 330 0.018
negative regulation of cell proliferation GO:0008285 296 0.018
carbohydrate homeostasis GO:0033500 128 0.018
response to endoplasmic reticulum stress GO:0034976 53 0.018
regulation of gtp catabolic process GO:0033124 113 0.018
spermatid development GO:0007286 108 0.018
polysaccharide metabolic process GO:0005976 39 0.018
skin development GO:0043588 220 0.018
chromatin modification GO:0016568 187 0.017
tissue homeostasis GO:0001894 115 0.017
neuronal action potential GO:0019228 54 0.017
regulation of anatomical structure size GO:0090066 178 0.017
small gtpase mediated signal transduction GO:0007264 97 0.017
glucose metabolic process GO:0006006 92 0.017
positive regulation of cellular component biogenesis GO:0044089 94 0.017
response to interleukin 4 GO:0070670 23 0.017
muscle system process GO:0003012 141 0.017
carbohydrate catabolic process GO:0016052 32 0.017
meiotic nuclear division GO:0007126 115 0.017
protein oligomerization GO:0051259 67 0.016
response to growth factor GO:0070848 198 0.016
dna alkylation GO:0006305 43 0.016
negative regulation of cellular component organization GO:0051129 194 0.016
intrinsic apoptotic signaling pathway GO:0097193 132 0.016
multicellular organismal homeostasis GO:0048871 164 0.016
cellular response to lipid GO:0071396 145 0.016
negative regulation of protein metabolic process GO:0051248 282 0.016
chromatin organization GO:0006325 206 0.016
anatomical structure homeostasis GO:0060249 145 0.016
regulation of purine nucleotide catabolic process GO:0033121 122 0.016
regulation of nucleotide catabolic process GO:0030811 122 0.016
retina development in camera type eye GO:0060041 119 0.016
cellular response to external stimulus GO:0071496 88 0.016
alpha amino acid metabolic process GO:1901605 59 0.016
protein targeting GO:0006605 143 0.015
ras protein signal transduction GO:0007265 77 0.015
regulation of system process GO:0044057 200 0.015
regulation of neuron apoptotic process GO:0043523 122 0.015
cellular lipid metabolic process GO:0044255 323 0.015
cellular polysaccharide metabolic process GO:0044264 38 0.015
photoreceptor cell differentiation GO:0046530 52 0.015
response to organonitrogen compound GO:0010243 246 0.015
neuron death GO:0070997 154 0.015
reactive oxygen species biosynthetic process GO:1903409 8 0.015
negative regulation of neuron death GO:1901215 98 0.015
mapk cascade GO:0000165 281 0.015
placenta development GO:0001890 140 0.015
establishment of protein localization to membrane GO:0090150 54 0.015
myelination GO:0042552 74 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.015
monocarboxylic acid metabolic process GO:0032787 191 0.015
vesicle organization GO:0016050 60 0.014
multi organism reproductive behavior GO:0044705 29 0.014
response to inorganic substance GO:0010035 96 0.014
ossification GO:0001503 216 0.014
digestive system development GO:0055123 200 0.014
cerebellum development GO:0021549 77 0.014
chemotaxis GO:0006935 247 0.014
leukocyte differentiation GO:0002521 342 0.014
metal ion homeostasis GO:0055065 189 0.014
response to extracellular stimulus GO:0009991 127 0.014
multi organism behavior GO:0051705 62 0.014
regulation of vesicle mediated transport GO:0060627 139 0.014
response to light stimulus GO:0009416 135 0.014
positive regulation of protein phosphorylation GO:0001934 242 0.014
regulation of response to wounding GO:1903034 189 0.014
epidermis development GO:0008544 187 0.014
ribosomal small subunit biogenesis GO:0042274 4 0.014
cellular lipid catabolic process GO:0044242 52 0.014
multicellular organismal aging GO:0010259 24 0.014
positive regulation of nucleoside metabolic process GO:0045979 91 0.013
response to epidermal growth factor GO:0070849 4 0.013
apoptotic signaling pathway GO:0097190 306 0.013
ensheathment of neurons GO:0007272 76 0.013
sensory organ morphogenesis GO:0090596 242 0.013
calcium ion homeostasis GO:0055074 127 0.013
response to reactive oxygen species GO:0000302 56 0.013
regulation of defense response GO:0031347 233 0.013
multicellular organismal reproductive behavior GO:0033057 23 0.013
cellular response to organonitrogen compound GO:0071417 145 0.013
ribonucleoside monophosphate catabolic process GO:0009158 57 0.013
cyclic nucleotide metabolic process GO:0009187 59 0.013
cellular macromolecule catabolic process GO:0044265 206 0.013
regulation of glucose metabolic process GO:0010906 60 0.013
protein localization to organelle GO:0033365 185 0.013
methylation GO:0032259 134 0.013
neural tube development GO:0021915 160 0.013
regulation of cytoplasmic transport GO:1903649 112 0.013
regulation of binding GO:0051098 111 0.013
negative regulation of transferase activity GO:0051348 85 0.013
neural tube formation GO:0001841 108 0.013
macroautophagy GO:0016236 21 0.013
autophagy GO:0006914 45 0.013
energy reserve metabolic process GO:0006112 39 0.013
guanosine containing compound catabolic process GO:1901069 144 0.013
organelle assembly GO:0070925 177 0.013
gliogenesis GO:0042063 141 0.013
positive regulation of gtpase activity GO:0043547 85 0.013
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.013
oogenesis GO:0048477 56 0.013
regulation of intracellular transport GO:0032386 159 0.012
organic acid catabolic process GO:0016054 51 0.012
actin filament organization GO:0007015 113 0.012
maintenance of location GO:0051235 89 0.012
positive regulation of growth GO:0045927 104 0.012
positive regulation of apoptotic process GO:0043065 217 0.012
lipid localization GO:0010876 126 0.012
negative regulation of kinase activity GO:0033673 81 0.012
mitotic cell cycle GO:0000278 195 0.012
Fly
protein processing GO:0016485 163 0.012
glucan metabolic process GO:0044042 32 0.012
reproductive behavior GO:0019098 32 0.012
positive regulation of binding GO:0051099 49 0.012
cell growth GO:0016049 130 0.012
positive regulation of programmed cell death GO:0043068 218 0.012
response to monosaccharide GO:0034284 67 0.012
cellular ion homeostasis GO:0006873 165 0.012
cellular divalent inorganic cation homeostasis GO:0072503 127 0.012
reactive oxygen species metabolic process GO:0072593 84 0.012
regulation of wnt signaling pathway GO:0030111 123 0.012
camp catabolic process GO:0006198 4 0.012
response to acid chemical GO:0001101 111 0.012
t cell activation GO:0042110 289 0.012
reactive nitrogen species metabolic process GO:2001057 0 0.012
organelle localization GO:0051640 179 0.012
positive regulation of hydrolase activity GO:0051345 148 0.012
ribonucleoprotein complex subunit organization GO:0071826 28 0.012
nucleocytoplasmic transport GO:0006913 139 0.012
positive regulation of apoptotic signaling pathway GO:2001235 95 0.012
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.011
positive regulation of protein catabolic process GO:0045732 60 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
peptidyl tyrosine modification GO:0018212 145 0.011
ameboidal type cell migration GO:0001667 128 0.011
lytic vacuole organization GO:0080171 21 0.011
lateral inhibition GO:0046331 1 0.011
fat cell differentiation GO:0045444 160 0.011
regulation of ion homeostasis GO:2000021 64 0.011
cell death in response to oxidative stress GO:0036473 24 0.011
regulation of cell growth GO:0001558 91 0.011
metencephalon development GO:0022037 89 0.011
muscle tissue development GO:0060537 308 0.011
negative regulation of proteolysis GO:0045861 74 0.011
positive regulation of kinase activity GO:0033674 155 0.011
cell division GO:0051301 120 0.011
immune effector process GO:0002252 321 0.011
epithelial cell proliferation GO:0050673 174 0.011
regulation of hormone levels GO:0010817 211 0.011
negative regulation of nervous system development GO:0051961 156 0.011
heart morphogenesis GO:0003007 178 0.011
meiosis i GO:0007127 60 0.011
axon ensheathment GO:0008366 76 0.011
response to radiation GO:0009314 165 0.011
nitrogen compound transport GO:0071705 271 0.011
synapsis GO:0007129 34 0.011
regulation of cellular component size GO:0032535 121 0.011
cytokine production GO:0001816 319 0.011
meiotic cell cycle process GO:1903046 77 0.010
positive regulation of cellular catabolic process GO:0031331 148 0.010
cation homeostasis GO:0055080 212 0.010
transmembrane transport GO:0055085 412 0.010
lipid catabolic process GO:0016042 69 0.010
membrane depolarization GO:0051899 64 0.010
negative regulation of cellular catabolic process GO:0031330 47 0.010
fertilization GO:0009566 127 0.010
regulation of translation GO:0006417 71 0.010
Human
regulation of cellular response to stress GO:0080135 159 0.010
small molecule catabolic process GO:0044282 71 0.010
cerebellar purkinje cell layer development GO:0021680 26 0.010
photoreceptor cell development GO:0042461 40 0.010

Eef2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.040
nervous system disease DOID:863 0 0.040
sensory system disease DOID:0050155 0 0.015
central nervous system disease DOID:331 0 0.015
immune system disease DOID:2914 0 0.015
neurodegenerative disease DOID:1289 0 0.013
disease of metabolism DOID:0014667 0 0.011