Mus musculus

0 known processes

Gsdma

gasdermin A

(Aliases: BB149167,Gsdm1,Gsdma1,Gsdm,H312E)

Gsdma biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular lipid metabolic process GO:0044255 323 0.181
extracellular structure organization GO:0043062 148 0.119
alcohol metabolic process GO:0006066 116 0.111
hematopoietic progenitor cell differentiation GO:0002244 143 0.104
leukocyte differentiation GO:0002521 342 0.097
regulation of lipid metabolic process GO:0019216 118 0.090
negative regulation of molecular function GO:0044092 258 0.073
protein maturation GO:0051604 176 0.068
male gamete generation GO:0048232 285 0.067
cellular amino acid metabolic process GO:0006520 103 0.066
cellular amine metabolic process GO:0044106 44 0.065
skin development GO:0043588 220 0.065
regulation of cellular ketone metabolic process GO:0010565 66 0.065
phospholipid metabolic process GO:0006644 87 0.064
macromolecule catabolic process GO:0009057 281 0.062
glycerolipid metabolic process GO:0046486 122 0.059
ion transmembrane transport GO:0034220 361 0.057
negative regulation of cellular component organization GO:0051129 194 0.053
regulation of leukocyte differentiation GO:1902105 159 0.052
regulation of neuron differentiation GO:0045664 281 0.052
spermatid differentiation GO:0048515 115 0.049
muscle tissue development GO:0060537 308 0.049
cellular response to lipid GO:0071396 145 0.048
cell type specific apoptotic process GO:0097285 268 0.047
membrane organization GO:0061024 245 0.046
extracellular matrix organization GO:0030198 147 0.046
protein localization to membrane GO:0072657 108 0.046
heterocycle catabolic process GO:0046700 280 0.044
regulation of proteolysis GO:0030162 164 0.044
regulation of cell activation GO:0050865 289 0.043
homeostasis of number of cells GO:0048872 210 0.043
blastocyst development GO:0001824 80 0.042
negative regulation of cellular protein metabolic process GO:0032269 247 0.040
positive regulation of programmed cell death GO:0043068 218 0.040
camera type eye development GO:0043010 266 0.039
lymphocyte differentiation GO:0030098 242 0.038
organic hydroxy compound metabolic process GO:1901615 203 0.038
cellular ketone metabolic process GO:0042180 84 0.037
hair follicle morphogenesis GO:0031069 29 0.037
developmental maturation GO:0021700 193 0.036
regulation of hydrolase activity GO:0051336 246 0.035
cellular macromolecule catabolic process GO:0044265 206 0.035
regulation of neuron projection development GO:0010975 169 0.035
negative regulation of cell proliferation GO:0008285 296 0.034
myeloid cell differentiation GO:0030099 233 0.034
hair cycle GO:0042633 90 0.034
regulation of ion transport GO:0043269 215 0.034
aromatic compound catabolic process GO:0019439 286 0.034
spermatogenesis GO:0007283 284 0.033
protein processing GO:0016485 163 0.033
epidermis development GO:0008544 187 0.033
anatomical structure homeostasis GO:0060249 145 0.033
regulation of cell projection organization GO:0031344 206 0.033
regulation of cellular amine metabolic process GO:0033238 20 0.033
erythrocyte differentiation GO:0030218 88 0.033
response to organonitrogen compound GO:0010243 246 0.032
myeloid cell homeostasis GO:0002262 114 0.032
chemotaxis GO:0006935 247 0.032
positive regulation of organelle organization GO:0010638 128 0.031
lens development in camera type eye GO:0002088 62 0.031
ribonucleoside catabolic process GO:0042454 206 0.031
myeloid leukocyte differentiation GO:0002573 119 0.031
small gtpase mediated signal transduction GO:0007264 97 0.031
peptide hormone secretion GO:0030072 109 0.030
fatty acid metabolic process GO:0006631 121 0.030
cellular nitrogen compound catabolic process GO:0044270 280 0.029
spermatid development GO:0007286 108 0.029
response to acid chemical GO:0001101 111 0.029
lipid biosynthetic process GO:0008610 179 0.029
inorganic ion transmembrane transport GO:0098660 234 0.029
wound healing GO:0042060 157 0.029
single organism cell adhesion GO:0098602 156 0.028
intermediate filament based process GO:0045103 27 0.028
amine metabolic process GO:0009308 45 0.028
regulation of secretion GO:0051046 274 0.027
establishment of protein localization to membrane GO:0090150 54 0.027
inorganic cation transmembrane transport GO:0098662 207 0.027
organic cyclic compound catabolic process GO:1901361 295 0.027
regulation of blood pressure GO:0008217 93 0.027
amide transport GO:0042886 138 0.027
response to inactivity GO:0014854 4 0.027
negative regulation of lipid metabolic process GO:0045833 30 0.026
cellular protein catabolic process GO:0044257 155 0.026
cation transport GO:0006812 399 0.026
regulation of myeloid cell differentiation GO:0045637 96 0.026
positive regulation of cellular amine metabolic process GO:0033240 5 0.025
embryonic placenta development GO:0001892 98 0.025
actin cytoskeleton organization GO:0030036 220 0.025
regulation of homeostatic process GO:0032844 182 0.025
actin polymerization or depolymerization GO:0008154 54 0.025
organophosphate catabolic process GO:0046434 232 0.025
regulation of cellular catabolic process GO:0031329 242 0.024
microtubule cytoskeleton organization GO:0000226 157 0.023
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.023
Mouse
limb morphogenesis GO:0035108 149 0.023
monocarboxylic acid metabolic process GO:0032787 191 0.023
regulation of protein catabolic process GO:0042176 108 0.023
protein localization to plasma membrane GO:0072659 57 0.023
nitrogen compound transport GO:0071705 271 0.023
carbohydrate derivative catabolic process GO:1901136 231 0.023
hormone secretion GO:0046879 128 0.022
organelle fission GO:0048285 170 0.022
peptide secretion GO:0002790 114 0.022
intermediate filament cytoskeleton organization GO:0045104 26 0.022
actin filament organization GO:0007015 113 0.022
actin filament polymerization GO:0030041 44 0.022
olfactory learning GO:0008355 2 0.022
regulation of organelle organization GO:0033043 289 0.022
intermediate filament organization GO:0045109 15 0.022
lipid localization GO:0010876 126 0.022
regulation of endopeptidase activity GO:0052548 89 0.021
cellular lipid catabolic process GO:0044242 52 0.021
respiratory system development GO:0060541 190 0.021
cardiac chamber development GO:0003205 108 0.021
cellular chemical homeostasis GO:0055082 215 0.021
regulation of hormone levels GO:0010817 211 0.021
innate immune response GO:0045087 157 0.021
cardiac chamber morphogenesis GO:0003206 93 0.021
cell adhesion GO:0007155 329 0.021
regulation of peptidase activity GO:0052547 96 0.021
cellular response to organonitrogen compound GO:0071417 145 0.021
epidermis morphogenesis GO:0048730 33 0.021
regulation of neuron death GO:1901214 134 0.020
regulation of protein localization GO:0032880 231 0.020
appendage morphogenesis GO:0035107 149 0.020
kidney development GO:0001822 213 0.020
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.020
cellular response to calcium ion GO:0071277 14 0.020
canonical wnt signaling pathway GO:0060070 130 0.020
translation GO:0006412 93 0.020
nucleoside phosphate metabolic process GO:0006753 338 0.020
cellular response to organic cyclic compound GO:0071407 87 0.020
regulation of cellular amino acid metabolic process GO:0006521 5 0.020
sulfur compound metabolic process GO:0006790 100 0.020
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.020
response to peptide GO:1901652 136 0.020
chromatin organization GO:0006325 206 0.020
positive regulation of transferase activity GO:0051347 167 0.020
hair follicle development GO:0001942 85 0.020
negative regulation of transferase activity GO:0051348 85 0.020
negative regulation of protein metabolic process GO:0051248 282 0.019
regulation of intracellular transport GO:0032386 159 0.019
cation transmembrane transport GO:0098655 266 0.019
regulation of lymphocyte differentiation GO:0045619 107 0.019
regulation of metal ion transport GO:0010959 106 0.019
regulation of cytoplasmic transport GO:1903649 112 0.019
organonitrogen compound catabolic process GO:1901565 264 0.019
peptide transport GO:0015833 133 0.019
cardiac muscle tissue development GO:0048738 130 0.019
leukocyte mediated immunity GO:0002443 174 0.018
regulation of system process GO:0044057 200 0.018
regulation of organ morphogenesis GO:2000027 144 0.018
protein catabolic process GO:0030163 221 0.018
regulation of secretion by cell GO:1903530 249 0.018
positive regulation of growth GO:0045927 104 0.018
production of molecular mediator of immune response GO:0002440 103 0.018
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.018
skeletal muscle organ development GO:0060538 163 0.018
negative regulation of hydrolase activity GO:0051346 71 0.018
purine ribonucleoside catabolic process GO:0046130 205 0.018
fertilization GO:0009566 127 0.018
t cell activation GO:0042110 289 0.018
regulation of protein complex assembly GO:0043254 83 0.017
antibacterial peptide biosynthetic process GO:0002780 2 0.017
multicellular organismal homeostasis GO:0048871 164 0.017
nucleoside triphosphate metabolic process GO:0009141 230 0.017
modification dependent macromolecule catabolic process GO:0043632 133 0.017
organic acid biosynthetic process GO:0016053 86 0.017
regulation of body fluid levels GO:0050878 162 0.017
posttranscriptional regulation of gene expression GO:0010608 155 0.017
synapse organization GO:0050808 125 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.017
negative regulation of endopeptidase activity GO:0010951 44 0.017
steroid metabolic process GO:0008202 119 0.017
striated muscle contraction GO:0006941 45 0.017
muscle system process GO:0003012 141 0.017
purine ribonucleoside metabolic process GO:0046128 241 0.017
regulation of transferase activity GO:0051338 263 0.017
regulation of cellular component size GO:0032535 121 0.017
ras protein signal transduction GO:0007265 77 0.017
regulation of lymphocyte activation GO:0051249 240 0.017
positive regulation of lipid kinase activity GO:0090218 11 0.017
organonitrogen compound biosynthetic process GO:1901566 192 0.017
small molecule biosynthetic process GO:0044283 132 0.016
regulation of lipid biosynthetic process GO:0046890 54 0.016
cellular homeostasis GO:0019725 240 0.016
leukocyte proliferation GO:0070661 172 0.016
placenta development GO:0001890 140 0.016
carbohydrate homeostasis GO:0033500 128 0.016
oocyte construction GO:0007308 2 0.016
positive regulation of interleukin 8 production GO:0032757 2 0.016
nuclear division GO:0000280 158 0.016
regulation of cell cycle GO:0051726 281 0.016
regulation of defense response GO:0031347 233 0.016
metanephric loop of henle development GO:0072236 4 0.016
lymphocyte apoptotic process GO:0070227 54 0.016
microtubule based process GO:0007017 236 0.016
cofactor transport GO:0051181 4 0.016
gonad development GO:0008406 141 0.016
response to peptide hormone GO:0043434 127 0.015
cell communication by chemical coupling GO:0010643 2 0.015
glycerophospholipid metabolic process GO:0006650 71 0.015
positive regulation of leukocyte differentiation GO:1902107 86 0.015
negative regulation of proteolysis GO:0045861 74 0.015
triglyceride metabolic process GO:0006641 51 0.015
blood circulation GO:0008015 195 0.015
stem cell development GO:0048864 219 0.015
intermediate filament bundle assembly GO:0045110 3 0.015
regulation of transmembrane transport GO:0034762 128 0.015
single organismal cell cell adhesion GO:0016337 131 0.015
purine nucleoside catabolic process GO:0006152 205 0.015
gland development GO:0048732 330 0.015
stem cell differentiation GO:0048863 268 0.015
monocarboxylic acid biosynthetic process GO:0072330 61 0.015
regulation of ion transmembrane transport GO:0034765 119 0.015
carboxylic acid biosynthetic process GO:0046394 86 0.015
negative regulation of kinase activity GO:0033673 81 0.015
positive regulation of lipid metabolic process GO:0045834 40 0.015
modification dependent protein catabolic process GO:0019941 133 0.015
negative regulation of peptidase activity GO:0010466 46 0.015
negative regulation of phosphorylation GO:0042326 166 0.015
negative regulation of immune system process GO:0002683 209 0.015
cytoplasmic transport GO:0016482 234 0.014
sterol metabolic process GO:0016125 58 0.014
transmembrane transport GO:0055085 412 0.014
glycosyl compound catabolic process GO:1901658 206 0.014
regulation of tissue remodeling GO:0034103 38 0.014
peptidyl serine modification GO:0018209 83 0.014
response to molecule of bacterial origin GO:0002237 143 0.014
positive regulation of cell death GO:0010942 224 0.014
cellular response to hormone stimulus GO:0032870 150 0.014
striated muscle tissue development GO:0014706 293 0.014
cellular amide metabolic process GO:0043603 58 0.014
negative regulation of protein modification process GO:0031400 163 0.014
glial cell differentiation GO:0010001 131 0.014
skin morphogenesis GO:0043589 38 0.014
axon target recognition GO:0007412 4 0.014
cellular response to acid chemical GO:0071229 68 0.014
negative regulation of phosphate metabolic process GO:0045936 184 0.014
axis elongation involved in somitogenesis GO:0090245 4 0.014
response to calcium ion GO:0051592 20 0.014
satellite cell activation involved in skeletal muscle regeneration GO:0014901 3 0.014
neutral lipid metabolic process GO:0006638 57 0.014
endomembrane system organization GO:0010256 147 0.014
response to steroid hormone GO:0048545 56 0.014
response to retinoic acid GO:0032526 56 0.013
protein ubiquitination GO:0016567 171 0.013
renal system development GO:0072001 225 0.013
protein modification by small protein conjugation GO:0032446 187 0.013
tube closure GO:0060606 91 0.013
negative regulation of protein maturation GO:1903318 79 0.013
establishment of protein localization to plasma membrane GO:0090002 34 0.013
circulatory system process GO:0003013 197 0.013
insulin secretion GO:0030073 89 0.013
septum primum development GO:0003284 4 0.013
cellular modified amino acid metabolic process GO:0006575 63 0.013
neuron death GO:0070997 154 0.013
neuromuscular process GO:0050905 99 0.013
cellular response to cytokine stimulus GO:0071345 189 0.013
positive regulation of t cell differentiation GO:0045582 52 0.013
viral gene expression GO:0019080 3 0.013
response to radiation GO:0009314 165 0.013
response to light stimulus GO:0009416 135 0.013
regulation of establishment of protein localization GO:0070201 181 0.013
germ cell development GO:0007281 185 0.013
response to amino acid GO:0043200 37 0.013
axonogenesis GO:0007409 274 0.013
canonical wnt signaling pathway involved in regulation of cell proliferation GO:0044340 3 0.013
development of primary sexual characteristics GO:0045137 143 0.013
cellular response to metal ion GO:0071248 31 0.013
sterol homeostasis GO:0055092 45 0.013
regulation of actin polymerization or depolymerization GO:0008064 45 0.013
glycosyl compound metabolic process GO:1901657 246 0.013
purine containing compound catabolic process GO:0072523 213 0.013
regulation of actin filament based process GO:0032970 99 0.013
reactive oxygen species metabolic process GO:0072593 84 0.013
ubiquitin dependent protein catabolic process GO:0006511 129 0.013
zygotic determination of anterior posterior axis embryo GO:0007354 3 0.013
negative regulation of epithelial cell proliferation GO:0050680 64 0.013
muscle cell differentiation GO:0042692 261 0.013
positive regulation of apoptotic process GO:0043065 217 0.013
exocytosis GO:0006887 121 0.013
regulation of cytokine production GO:0001817 266 0.013
asymmetric stem cell division GO:0098722 3 0.013
response to inorganic substance GO:0010035 96 0.012
b cell activation GO:0042113 161 0.012
purine nucleotide catabolic process GO:0006195 211 0.012
citrulline biosynthetic process GO:0019240 2 0.012
neuron apoptotic process GO:0051402 142 0.012
response to insulin GO:0032868 100 0.012
hydrogen transport GO:0006818 35 0.012
multi multicellular organism process GO:0044706 109 0.012
male sex differentiation GO:0046661 109 0.012
urogenital system development GO:0001655 261 0.012
regulation of cellular component biogenesis GO:0044087 181 0.012
oocyte axis specification GO:0007309 2 0.012
fatty acid transport GO:0015908 28 0.012
positive regulation of homeostatic process GO:0032846 64 0.012
locomotory behavior GO:0007626 195 0.012
regulation of cell motility GO:2000145 236 0.012
negative regulation of neuron death GO:1901215 98 0.012
negative regulation of calcium ion dependent exocytosis GO:0045955 3 0.012
response to monosaccharide GO:0034284 67 0.012
regulation of reactive oxygen species metabolic process GO:2000377 40 0.012
regulation of actin filament length GO:0030832 45 0.012
molting cycle GO:0042303 90 0.012
regulation of binding GO:0051098 111 0.012
phosphatidylethanolamine biosynthetic process GO:0006646 2 0.012
negative regulation of protein phosphorylation GO:0001933 126 0.012
response to extracellular stimulus GO:0009991 127 0.012
regulation of b cell activation GO:0050864 81 0.012
multicellular organismal signaling GO:0035637 91 0.012
regulation of t cell activation GO:0050863 170 0.012
positive regulation of lymphocyte activation GO:0051251 140 0.012
ensheathment of neurons GO:0007272 76 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.012
regulation of actin cytoskeleton organization GO:0032956 84 0.012
female gamete generation GO:0007292 74 0.012
nucleobase containing small molecule metabolic process GO:0055086 352 0.012
regulation of response to wounding GO:1903034 189 0.012
regulation of t cell differentiation GO:0045580 83 0.012
ossification GO:0001503 216 0.012
cellular response to inorganic substance GO:0071241 37 0.012
morphogenesis of embryonic epithelium GO:0016331 159 0.012
engulfment of apoptotic cell GO:0043652 3 0.012
ear development GO:0043583 200 0.012
regulation of cell growth GO:0001558 91 0.012
positive regulation of lymphocyte differentiation GO:0045621 61 0.012
single fertilization GO:0007338 82 0.012
sodium ion transport GO:0006814 73 0.012
regulation of ossification GO:0030278 112 0.011
regulation of renin secretion into blood stream GO:1900133 4 0.011
synaptic transmission GO:0007268 329 0.011
positive regulation of neuron differentiation GO:0045666 141 0.011
response to starvation GO:0042594 65 0.011
intracellular mrna localization GO:0008298 4 0.011
skeletal system development GO:0001501 356 0.011
muscle tissue morphogenesis GO:0060415 53 0.011
negative regulation of organelle organization GO:0010639 90 0.011
connective tissue replacement involved in inflammatory response wound healing GO:0002248 3 0.011
dna metabolic process GO:0006259 303 0.011
glucose homeostasis GO:0042593 128 0.011
mesenchymal cell differentiation GO:0048762 107 0.011
ribonucleoside monophosphate metabolic process GO:0009161 80 0.011
cell differentiation involved in embryonic placenta development GO:0060706 26 0.011
carboxylic acid transport GO:0046942 100 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.011
regulation of cell adhesion GO:0030155 154 0.011
positive regulation of necrotic cell death GO:0010940 1 0.011
regulation of anagen GO:0051884 1 0.011
rac protein signal transduction GO:0016601 13 0.011
proton transport GO:0015992 35 0.011
developmental cell growth GO:0048588 84 0.011
cellular response to insulin stimulus GO:0032869 78 0.011
acylglycerol metabolic process GO:0006639 55 0.011
positive regulation of protein modification process GO:0031401 299 0.011
cell growth GO:0016049 130 0.011
peptidyl serine phosphorylation GO:0018105 74 0.011
positive regulation of mapk cascade GO:0043410 170 0.011
regulation of bone remodeling GO:0046850 28 0.011
response to metal ion GO:0010038 47 0.011
cellular response to steroid hormone stimulus GO:0071383 33 0.011
pharynx development GO:0060465 1 0.011
cell maturation GO:0048469 127 0.011
regulation of membrane depolarization during action potential GO:0098902 1 0.011
mesenchyme development GO:0060485 152 0.011
keratinocyte differentiation GO:0030216 48 0.011
sa node cell action potential GO:0086015 4 0.011
dephosphorylation GO:0016311 129 0.011
cellular response to nutrient levels GO:0031669 64 0.011
positive regulation of proteolysis GO:0045862 85 0.011
rna processing GO:0006396 105 0.011
regulation of leukocyte apoptotic process GO:2000106 56 0.011
sodium ion transmembrane transport GO:0035725 49 0.011
positive regulation of hydrolase activity GO:0051345 148 0.011
cellular response to starvation GO:0009267 57 0.011
response to muscle inactivity GO:0014870 4 0.011
blood coagulation GO:0007596 76 0.011
positive regulation of cell activation GO:0050867 158 0.011
meiotic cell cycle GO:0051321 122 0.011
compound eye development GO:0048749 1 0.010
regulation of cysteine type endopeptidase activity GO:2000116 65 0.010
regulation of peptide secretion GO:0002791 77 0.010
positive regulation of vasoconstriction GO:0045907 4 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.010
biomineral tissue development GO:0031214 64 0.010
central nervous system vasculogenesis GO:0022009 3 0.010
peptidyl amino acid modification GO:0018193 336 0.010
oligopeptide transmembrane transport GO:0035672 4 0.010
response to denervation involved in regulation of muscle adaptation GO:0014894 4 0.010
meiotic nuclear division GO:0007126 115 0.010
granulocyte differentiation GO:0030851 17 0.010
regulation of lymphocyte apoptotic process GO:0070228 41 0.010
cardiac muscle contraction GO:0060048 32 0.010
regulation of anatomical structure size GO:0090066 178 0.010
cellular response to extracellular stimulus GO:0031668 81 0.010
oviduct development GO:0060066 3 0.010
regulation of phosphatidylcholine biosynthetic process GO:2001245 2 0.010
rho protein signal transduction GO:0007266 32 0.010
calcium ion dependent exocytosis GO:0017156 35 0.010
regulation of cell migration GO:0030334 219 0.010
positive regulation of skeletal muscle tissue regeneration GO:0043415 4 0.010
regulation of protein kinase activity GO:0045859 232 0.010
auditory receptor cell fate specification GO:0042667 1 0.010
purine ribonucleotide metabolic process GO:0009150 290 0.010
adult locomotory behavior GO:0008344 91 0.010
positive regulation of secretion GO:0051047 130 0.010
skeletal muscle cell differentiation GO:0035914 66 0.010
appendage development GO:0048736 166 0.010
epithelial tube morphogenesis GO:0060562 303 0.010
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.010
pole plasm assembly GO:0007315 2 0.010
milk ejection GO:0060156 1 0.010

Gsdma disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
musculoskeletal system disease DOID:17 0 0.016
nervous system disease DOID:863 0 0.011