Mus musculus

11 known processes

Gsdmd

gasdermin D

(Aliases: AW558049,M2-4,DF5L,1810036L03Rik,Dfna5l,Gsdmdc1)

Gsdmd biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
immune effector process GO:0002252 321 0.218
heterocycle catabolic process GO:0046700 280 0.166
regulation of innate immune response GO:0045088 91 0.161
organic cyclic compound catabolic process GO:1901361 295 0.147
regulation of hydrolase activity GO:0051336 246 0.137
purine containing compound metabolic process GO:0072521 311 0.120
nucleobase containing small molecule metabolic process GO:0055086 352 0.117
cellular nitrogen compound catabolic process GO:0044270 280 0.109
cell activation involved in immune response GO:0002263 126 0.108
innate immune response GO:0045087 157 0.106
interspecies interaction between organisms GO:0044419 83 0.102
regulation of cytokine production GO:0001817 266 0.102
negative regulation of multi organism process GO:0043901 68 0.101
aromatic compound catabolic process GO:0019439 286 0.097
activation of immune response GO:0002253 138 0.096
regulation of defense response GO:0031347 233 0.095
glycosyl compound metabolic process GO:1901657 246 0.094
ribonucleoside metabolic process GO:0009119 245 0.094
positive regulation of innate immune response GO:0045089 80 0.088
ras protein signal transduction GO:0007265 77 0.084
nucleotide metabolic process GO:0009117 332 0.081
ribose phosphate metabolic process GO:0019693 291 0.079
defense response to other organism GO:0098542 197 0.077
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.076
nucleoside phosphate metabolic process GO:0006753 338 0.074
purine ribonucleotide catabolic process GO:0009154 208 0.073
leukocyte differentiation GO:0002521 342 0.073
positive regulation of programmed cell death GO:0043068 218 0.072
Mouse
positive regulation of cell death GO:0010942 224 0.072
Mouse
viral process GO:0016032 41 0.072
response to molecule of bacterial origin GO:0002237 143 0.071
regulation of organelle organization GO:0033043 289 0.071
ribonucleoside catabolic process GO:0042454 206 0.070
macromolecule catabolic process GO:0009057 281 0.069
purine nucleotide metabolic process GO:0006163 302 0.068
activation of innate immune response GO:0002218 56 0.068
lymphocyte mediated immunity GO:0002449 139 0.067
leukocyte proliferation GO:0070661 172 0.065
cytokine production GO:0001816 319 0.065
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.064
cellular response to dna damage stimulus GO:0006974 207 0.062
response to lipopolysaccharide GO:0032496 128 0.061
positive regulation of hydrolase activity GO:0051345 148 0.059
immune response activating signal transduction GO:0002757 116 0.058
nucleoside metabolic process GO:0009116 246 0.057
lymphocyte activation involved in immune response GO:0002285 93 0.057
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.057
cell adhesion GO:0007155 329 0.056
carbohydrate derivative catabolic process GO:1901136 231 0.055
ribonucleotide metabolic process GO:0009259 291 0.054
positive regulation of apoptotic process GO:0043065 217 0.051
Mouse
cellular macromolecule catabolic process GO:0044265 206 0.051
ribonucleoside triphosphate metabolic process GO:0009199 220 0.051
immune response regulating signaling pathway GO:0002764 125 0.051
purine containing compound catabolic process GO:0072523 213 0.050
regulation of cellular component biogenesis GO:0044087 181 0.050
ribonucleoside triphosphate catabolic process GO:0009203 199 0.049
small gtpase mediated signal transduction GO:0007264 97 0.049
regulation of cellular amino acid metabolic process GO:0006521 5 0.049
purine ribonucleoside catabolic process GO:0046130 205 0.049
homeostasis of number of cells GO:0048872 210 0.048
leukocyte activation involved in immune response GO:0002366 126 0.047
t cell activation involved in immune response GO:0002286 43 0.047
positive regulation of defense response GO:0031349 124 0.047
dna metabolic process GO:0006259 303 0.046
myeloid leukocyte differentiation GO:0002573 119 0.046
gland development GO:0048732 330 0.046
Mouse
cellular amine metabolic process GO:0044106 44 0.046
purine ribonucleoside metabolic process GO:0046128 241 0.045
negative regulation of lymphocyte activation GO:0051250 91 0.045
negative regulation of immune system process GO:0002683 209 0.043
regulation of multi organism process GO:0043900 111 0.042
regulation of purine nucleotide catabolic process GO:0033121 122 0.042
nucleoside phosphate catabolic process GO:1901292 222 0.041
guanosine containing compound metabolic process GO:1901068 144 0.040
t cell activation GO:0042110 289 0.040
nucleoside catabolic process GO:0009164 206 0.040
cation transport GO:0006812 399 0.040
purine ribonucleotide metabolic process GO:0009150 290 0.040
leukocyte mediated immunity GO:0002443 174 0.039
myeloid cell differentiation GO:0030099 233 0.039
transmembrane transport GO:0055085 412 0.039
cellular amino acid metabolic process GO:0006520 103 0.039
purine nucleotide catabolic process GO:0006195 211 0.038
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.038
nucleoside triphosphate metabolic process GO:0009141 230 0.038
negative regulation of molecular function GO:0044092 258 0.037
regulation of ras protein signal transduction GO:0046578 114 0.037
regulation of purine nucleotide metabolic process GO:1900542 169 0.037
posttranscriptional regulation of gene expression GO:0010608 155 0.037
regulation of proteolysis GO:0030162 164 0.037
response to organic cyclic compound GO:0014070 198 0.036
cellular ketone metabolic process GO:0042180 84 0.036
regulation of protein localization GO:0032880 231 0.036
cellular response to lipopolysaccharide GO:0071222 77 0.036
positive regulation of type i interferon production GO:0032481 14 0.036
purine nucleoside triphosphate catabolic process GO:0009146 203 0.036
protein modification by small protein conjugation or removal GO:0070647 207 0.036
carbohydrate metabolic process GO:0005975 230 0.035
ion transmembrane transport GO:0034220 361 0.035
cell type specific apoptotic process GO:0097285 268 0.034
chromatin organization GO:0006325 206 0.034
negative regulation of protein metabolic process GO:0051248 282 0.034
organophosphate catabolic process GO:0046434 232 0.034
regulation of cellular ketone metabolic process GO:0010565 66 0.033
cellular response to cytokine stimulus GO:0071345 189 0.033
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.033
glycosyl compound catabolic process GO:1901658 206 0.033
regulation of cellular catabolic process GO:0031329 242 0.033
muscle cell differentiation GO:0042692 261 0.033
pattern recognition receptor signaling pathway GO:0002221 47 0.033
histone modification GO:0016570 159 0.033
cellular response to biotic stimulus GO:0071216 92 0.033
negative regulation of viral genome replication GO:0045071 10 0.032
negative regulation of cellular component organization GO:0051129 194 0.032
regulation of cellular amine metabolic process GO:0033238 20 0.031
ribonucleotide catabolic process GO:0009261 208 0.031
purine nucleoside metabolic process GO:0042278 241 0.031
stem cell differentiation GO:0048863 268 0.031
Mouse
mapk cascade GO:0000165 281 0.031
lymphocyte proliferation GO:0046651 164 0.030
purine nucleoside triphosphate metabolic process GO:0009144 226 0.030
protein maturation GO:0051604 176 0.030
protein catabolic process GO:0030163 221 0.030
organonitrogen compound biosynthetic process GO:1901566 192 0.029
protein ubiquitination GO:0016567 171 0.029
regulation of leukocyte proliferation GO:0070663 121 0.029
purine nucleoside catabolic process GO:0006152 205 0.029
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.029
peptidyl amino acid modification GO:0018193 336 0.029
regulation of nucleotide metabolic process GO:0006140 169 0.029
positive regulation of kinase activity GO:0033674 155 0.028
positive regulation of cellular catabolic process GO:0031331 148 0.028
regulation of lymphocyte activation GO:0051249 240 0.028
alpha beta t cell differentiation GO:0046632 69 0.028
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.028
guanosine containing compound catabolic process GO:1901069 144 0.027
reactive oxygen species metabolic process GO:0072593 84 0.027
response to radiation GO:0009314 165 0.027
positive regulation of cytokine production GO:0001819 174 0.027
defense response to bacterium GO:0042742 119 0.027
leukocyte mediated cytotoxicity GO:0001909 62 0.027
nucleoside triphosphate catabolic process GO:0009143 205 0.027
epithelial cell proliferation GO:0050673 174 0.026
cellular response to lipid GO:0071396 145 0.026
epidermis development GO:0008544 187 0.026
Mouse
regulation of membrane potential GO:0042391 192 0.026
gtp catabolic process GO:0006184 143 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.026
positive regulation of nucleotide catabolic process GO:0030813 88 0.026
gtp metabolic process GO:0046039 144 0.026
negative regulation of cell activation GO:0050866 111 0.026
learning or memory GO:0007611 148 0.025
chromatin modification GO:0016568 187 0.025
regulation of leukocyte differentiation GO:1902105 159 0.025
protein modification by small protein conjugation GO:0032446 187 0.025
male gamete generation GO:0048232 285 0.025
spermatogenesis GO:0007283 284 0.025
nitrogen compound transport GO:0071705 271 0.024
lymphocyte homeostasis GO:0002260 64 0.024
regulation of nucleotide catabolic process GO:0030811 122 0.024
positive regulation of cellular amine metabolic process GO:0033240 5 0.024
negative regulation of cellular amine metabolic process GO:0033239 1 0.024
viral life cycle GO:0019058 36 0.024
t cell proliferation GO:0042098 120 0.024
regulation of cell activation GO:0050865 289 0.023
negative regulation of cell proliferation GO:0008285 296 0.023
positive regulation of immune effector process GO:0002699 107 0.023
muscle tissue development GO:0060537 308 0.023
interleukin 1 production GO:0032612 31 0.023
monocarboxylic acid metabolic process GO:0032787 191 0.023
regulation of secretion by cell GO:1903530 249 0.023
nucleotide catabolic process GO:0009166 217 0.023
cytoplasmic transport GO:0016482 234 0.023
regulation of adaptive immune response GO:0002819 90 0.023
regulation of inflammatory response GO:0050727 147 0.023
regulation of leukocyte mediated immunity GO:0002703 104 0.023
cytokine mediated signaling pathway GO:0019221 115 0.023
regulation of kinase activity GO:0043549 249 0.023
modification dependent macromolecule catabolic process GO:0043632 133 0.023
leukocyte homeostasis GO:0001776 79 0.022
cellular protein catabolic process GO:0044257 155 0.022
positive regulation of nucleotide metabolic process GO:0045981 114 0.022
rna interference GO:0016246 2 0.022
microtubule based process GO:0007017 236 0.022
regulation of hormone levels GO:0010817 211 0.022
positive regulation of proteolysis GO:0045862 85 0.022
regulation of cell migration GO:0030334 219 0.022
regulation of peptidase activity GO:0052547 96 0.021
intracellular protein transport GO:0006886 204 0.021
type i interferon production GO:0032606 29 0.021
positive regulation of interferon alpha production GO:0032727 4 0.021
positive regulation of gtp catabolic process GO:0033126 85 0.021
membrane organization GO:0061024 245 0.021
defense response to virus GO:0051607 68 0.021
inflammatory response GO:0006954 244 0.021
cellular response to organonitrogen compound GO:0071417 145 0.021
organonitrogen compound catabolic process GO:1901565 264 0.021
inorganic ion transmembrane transport GO:0098660 234 0.021
multicellular organismal homeostasis GO:0048871 164 0.021
regulation of ion transport GO:0043269 215 0.020
lymphocyte differentiation GO:0030098 242 0.020
actin cytoskeleton organization GO:0030036 220 0.020
b cell mediated immunity GO:0019724 71 0.020
regulation of protein transport GO:0051223 163 0.020
covalent chromatin modification GO:0016569 163 0.020
regulation of cell motility GO:2000145 236 0.020
cellular response to molecule of bacterial origin GO:0071219 83 0.020
modification dependent protein catabolic process GO:0019941 133 0.020
interferon beta biosynthetic process GO:0045350 4 0.020
microtubule cytoskeleton organization GO:0000226 157 0.020
cognition GO:0050890 149 0.020
reactive nitrogen species metabolic process GO:2001057 0 0.020
endocytosis GO:0006897 168 0.019
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.019
regulation of endopeptidase activity GO:0052548 89 0.019
apoptotic signaling pathway GO:0097190 306 0.019
Mouse
regulation of interferon beta biosynthetic process GO:0045357 4 0.019
rho protein signal transduction GO:0007266 32 0.019
negative regulation of phosphorus metabolic process GO:0010563 184 0.019
positive regulation of protein modification process GO:0031401 299 0.019
production of molecular mediator of immune response GO:0002440 103 0.019
positive regulation of cell projection organization GO:0031346 95 0.019
amine metabolic process GO:0009308 45 0.019
viral genome replication GO:0019079 17 0.019
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.019
regulation of t cell activation GO:0050863 170 0.018
protein localization to organelle GO:0033365 185 0.018
protein autophosphorylation GO:0046777 61 0.018
skin development GO:0043588 220 0.018
Mouse
skeletal system development GO:0001501 356 0.018
protein localization to membrane GO:0072657 108 0.018
response to organonitrogen compound GO:0010243 246 0.018
regulation of t cell proliferation GO:0042129 92 0.018
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.018
regulation of secretion GO:0051046 274 0.018
positive regulation of lymphocyte activation GO:0051251 140 0.018
nucleotide biosynthetic process GO:0009165 78 0.018
positive regulation of gtpase activity GO:0043547 85 0.018
regulation of cytoskeleton organization GO:0051493 122 0.017
glial cell apoptotic process GO:0034349 3 0.017
regulation of cell adhesion GO:0030155 154 0.017
regulation of cell cycle GO:0051726 281 0.017
cell killing GO:0001906 67 0.017
negative regulation of cytokine production GO:0001818 84 0.017
organelle assembly GO:0070925 177 0.017
nucleocytoplasmic transport GO:0006913 139 0.017
divalent metal ion transport GO:0070838 172 0.017
regulation of nucleoside metabolic process GO:0009118 130 0.017
anatomical structure homeostasis GO:0060249 145 0.017
calcium ion transport GO:0006816 159 0.017
carbohydrate homeostasis GO:0033500 128 0.017
organophosphate biosynthetic process GO:0090407 122 0.017
purine nucleotide biosynthetic process GO:0006164 65 0.017
regulation of cell projection organization GO:0031344 206 0.017
learning GO:0007612 98 0.016
maintenance of location GO:0051235 89 0.016
regulation of mapk cascade GO:0043408 248 0.016
response to growth factor GO:0070848 198 0.016
carbohydrate derivative biosynthetic process GO:1901137 183 0.016
purine containing compound biosynthetic process GO:0072522 70 0.016
regulation of gtp catabolic process GO:0033124 113 0.016
cellular response to organic cyclic compound GO:0071407 87 0.016
negative regulation of leukocyte differentiation GO:1902106 51 0.016
endomembrane system organization GO:0010256 147 0.016
protein processing GO:0016485 163 0.016
b cell activation involved in immune response GO:0002312 50 0.016
adaptive immune response GO:0002250 155 0.016
rna catabolic process GO:0006401 29 0.016
cellular chemical homeostasis GO:0055082 215 0.016
regulation of lymphocyte proliferation GO:0050670 117 0.016
regulation of intracellular transport GO:0032386 159 0.016
gene silencing GO:0016458 38 0.016
dna recombination GO:0006310 92 0.016
blood vessel morphogenesis GO:0048514 285 0.016
lipid localization GO:0010876 126 0.016
multicellular organism growth GO:0035264 161 0.016
interleukin 8 production GO:0032637 4 0.016
intrinsic apoptotic signaling pathway GO:0097193 132 0.016
regulation of protein kinase activity GO:0045859 232 0.015
positive regulation of peptidase activity GO:0010952 49 0.015
respiratory system development GO:0060541 190 0.015
peptide transport GO:0015833 133 0.015
positive regulation of protein transport GO:0051222 93 0.015
cytokine biosynthetic process GO:0042089 68 0.015
response to dsrna GO:0043331 30 0.015
cation transmembrane transport GO:0098655 266 0.015
nuclear transport GO:0051169 139 0.015
immunoglobulin mediated immune response GO:0016064 69 0.015
neuron death GO:0070997 154 0.015
negative regulation of cellular protein metabolic process GO:0032269 247 0.015
respiratory tube development GO:0030323 167 0.015
necrotic cell death GO:0070265 30 0.014
cellular homeostasis GO:0019725 240 0.014
cellular component assembly involved in morphogenesis GO:0010927 139 0.014
positive regulation of protein phosphorylation GO:0001934 242 0.014
glycoprotein metabolic process GO:0009100 116 0.014
regulation of type i interferon production GO:0032479 22 0.014
positive regulation of cell development GO:0010720 237 0.014
protein alkylation GO:0008213 81 0.014
negative regulation of cell cycle GO:0045786 123 0.014
positive regulation of nucleoside metabolic process GO:0045979 91 0.014
positive regulation of cellular component biogenesis GO:0044089 94 0.014
regulation of lymphocyte mediated immunity GO:0002706 84 0.014
cytokine metabolic process GO:0042107 71 0.014
lung development GO:0030324 164 0.014
cd4 positive alpha beta t cell activation GO:0035710 45 0.014
regulation of cysteine type endopeptidase activity GO:2000116 65 0.014
positive regulation of t cell mediated cytotoxicity GO:0001916 15 0.014
forebrain development GO:0030900 302 0.014
organelle fission GO:0048285 170 0.014
negative regulation of organelle organization GO:0010639 90 0.014
cellular metal ion homeostasis GO:0006875 151 0.013
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.013
regulation of interleukin 1 alpha production GO:0032650 4 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.013
striated muscle tissue development GO:0014706 293 0.013
t helper cell differentiation GO:0042093 28 0.013
ubiquitin dependent protein catabolic process GO:0006511 129 0.013
regulation of lymphocyte differentiation GO:0045619 107 0.013
nucleoside phosphate biosynthetic process GO:1901293 79 0.013
digestive system development GO:0055123 200 0.013
angiogenesis GO:0001525 201 0.013
glycosylation GO:0070085 62 0.013
mitochondrion organization GO:0007005 134 0.013
b cell activation GO:0042113 161 0.013
cell fate commitment GO:0045165 210 0.013
regulation of body fluid levels GO:0050878 162 0.013
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.013
myosin filament assembly GO:0031034 2 0.013
neuron apoptotic process GO:0051402 142 0.013
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.013
sensory perception GO:0007600 245 0.013
regulation of cell killing GO:0031341 40 0.013
t cell mediated immunity GO:0002456 50 0.013
regulation of alpha beta t cell activation GO:0046634 53 0.013
protein methylation GO:0006479 81 0.013
lymphocyte apoptotic process GO:0070227 54 0.013
amide transport GO:0042886 138 0.013
extracellular structure organization GO:0043062 148 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.013
regulation of actin filament based process GO:0032970 99 0.013
positive regulation of apoptotic signaling pathway GO:2001235 95 0.013
Mouse
stem cell development GO:0048864 219 0.013
Mouse
synaptic transmission GO:0007268 329 0.013
regulation of vesicle mediated transport GO:0060627 139 0.013
positive regulation of secretion GO:0051047 130 0.013
negative regulation of phosphorylation GO:0042326 166 0.013
inorganic cation transmembrane transport GO:0098662 207 0.013
programmed necrotic cell death GO:0097300 28 0.013
body fluid secretion GO:0007589 53 0.012
regulation of ion transmembrane transport GO:0034765 119 0.012
developmental maturation GO:0021700 193 0.012
Mouse
ossification GO:0001503 216 0.012
regulation of neuron differentiation GO:0045664 281 0.012
response to light stimulus GO:0009416 135 0.012
peptidyl lysine modification GO:0018205 77 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
regulation of anatomical structure size GO:0090066 178 0.012
regulation of neuron death GO:1901214 134 0.012
cellular protein complex assembly GO:0043623 116 0.012
meiotic cell cycle GO:0051321 122 0.012
purine nucleoside monophosphate metabolic process GO:0009126 81 0.012
positive regulation of secretion by cell GO:1903532 114 0.012
actin filament organization GO:0007015 113 0.012
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.012
dendrite development GO:0016358 115 0.012
glucose homeostasis GO:0042593 128 0.012
viral transcription GO:0019083 3 0.012
divalent inorganic cation transport GO:0072511 178 0.012
positive regulation of cell activation GO:0050867 158 0.012
regulation of protein processing GO:0070613 96 0.012
actin filament polymerization GO:0030041 44 0.012
regionalization GO:0003002 337 0.012
stem cell maintenance GO:0019827 130 0.012
Mouse
protein targeting GO:0006605 143 0.012
regulation of establishment of protein localization GO:0070201 181 0.012
regulation of binding GO:0051098 111 0.012
nuclear division GO:0000280 158 0.012
regulation of homeostatic process GO:0032844 182 0.012
myeloid leukocyte activation GO:0002274 83 0.011
regulation of cytokine biosynthetic process GO:0042035 59 0.011
intracellular receptor signaling pathway GO:0030522 74 0.011
rac protein signal transduction GO:0016601 13 0.011
plasma membrane organization GO:0007009 90 0.011
protein acylation GO:0043543 64 0.011
ribonucleoside monophosphate metabolic process GO:0009161 80 0.011
regulation of cytoplasmic transport GO:1903649 112 0.011
regulation of apoptotic signaling pathway GO:2001233 197 0.011
Mouse
anion transport GO:0006820 177 0.011
alpha beta t cell activation GO:0046631 91 0.011
protein import GO:0017038 101 0.011
negative regulation of immune effector process GO:0002698 55 0.011
nuclear import GO:0051170 95 0.011
regulation of chromosome organization GO:0033044 83 0.011
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.011
action potential GO:0001508 78 0.011
nucleoside monophosphate metabolic process GO:0009123 85 0.011
regulation of rho protein signal transduction GO:0035023 71 0.011
regulation of protein complex assembly GO:0043254 83 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.011
regulation of intracellular protein transport GO:0033157 82 0.011
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.011
hair cycle GO:0042633 90 0.011
Mouse
atp metabolic process GO:0046034 75 0.011
connective tissue development GO:0061448 179 0.011
spermatid development GO:0007286 108 0.011
regulation of t cell differentiation GO:0045580 83 0.011
protein localization to plasma membrane GO:0072659 57 0.011
cell division GO:0051301 120 0.011
regulation of cd8 positive alpha beta t cell proliferation GO:2000564 1 0.011
peptidyl serine modification GO:0018209 83 0.011
positive regulation of type i interferon mediated signaling pathway GO:0060340 4 0.011
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.011
gene silencing by mirna GO:0035195 10 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
meiotic cell cycle process GO:1903046 77 0.011
regulation of protein catabolic process GO:0042176 108 0.011
metal ion homeostasis GO:0055065 189 0.011
positive regulation of growth GO:0045927 104 0.011
cell substrate adhesion GO:0031589 130 0.011
striated muscle myosin thick filament assembly GO:0071688 1 0.010
positive regulation of rho gtpase activity GO:0032321 41 0.010
regulation of production of molecular mediator of immune response GO:0002700 65 0.010
neuromuscular process GO:0050905 99 0.010
interferon gamma production GO:0032609 67 0.010
negative regulation of defense response GO:0031348 77 0.010
mrna metabolic process GO:0016071 84 0.010
lateral inhibition GO:0046331 1 0.010
regulation of actin cytoskeleton organization GO:0032956 84 0.010
regulation of neuron apoptotic process GO:0043523 122 0.010
protein import into nucleus GO:0006606 95 0.010
cellular lipid metabolic process GO:0044255 323 0.010
viral gene expression GO:0019080 3 0.010
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.010
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.010
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.010
regulation of endocytosis GO:0030100 69 0.010
response to acid chemical GO:0001101 111 0.010
heart morphogenesis GO:0003007 178 0.010
glycoprotein biosynthetic process GO:0009101 89 0.010
oxidation reduction process GO:0055114 342 0.010
positive regulation of ras gtpase activity GO:0032320 65 0.010
methylation GO:0032259 134 0.010
regulation of peptide transport GO:0090087 91 0.010

Gsdmd disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.026
disease of anatomical entity DOID:7 0 0.026
cancer DOID:162 0 0.017
disease of cellular proliferation DOID:14566 0 0.017
organ system cancer DOID:0050686 0 0.017
musculoskeletal system disease DOID:17 0 0.014
connective tissue disease DOID:65 0 0.014
disease of metabolism DOID:0014667 0 0.013
nervous system disease DOID:863 0 0.012
gastrointestinal system cancer DOID:3119 0 0.010