Mus musculus

39 known processes

Espl1

extra spindle poles-like 1 (S. cerevisiae)

(Aliases: AL024103,PRCE,Cerp,SSE,ESP1,AU045071)

Espl1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna metabolic process GO:0006259 303 0.260
chromatin organization GO:0006325 206 0.135
chromosome segregation GO:0007059 48 0.130
microtubule polymerization or depolymerization GO:0031109 26 0.119
dna repair GO:0006281 107 0.105
positive regulation of chromosome segregation GO:0051984 4 0.098
regulation of exit from mitosis GO:0007096 1 0.084
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.082
regulation of organelle organization GO:0033043 289 0.072
meiotic cell cycle GO:0051321 122 0.071
macromolecule catabolic process GO:0009057 281 0.071
male gamete generation GO:0048232 285 0.069
nuclear division GO:0000280 158 0.067
cellular protein catabolic process GO:0044257 155 0.067
regulation of cellular amine metabolic process GO:0033238 20 0.066
meiotic nuclear division GO:0007126 115 0.063
negative regulation of cellular protein metabolic process GO:0032269 247 0.063
meiotic cell cycle process GO:1903046 77 0.062
heterocycle catabolic process GO:0046700 280 0.061
cellular response to dna damage stimulus GO:0006974 207 0.058
protein modification by small protein conjugation or removal GO:0070647 207 0.057
organophosphate catabolic process GO:0046434 232 0.056
regulation of cellular amino acid metabolic process GO:0006521 5 0.056
purine ribonucleoside metabolic process GO:0046128 241 0.055
organelle assembly GO:0070925 177 0.055
organelle fission GO:0048285 170 0.055
nucleoside triphosphate metabolic process GO:0009141 230 0.054
cellular amine metabolic process GO:0044106 44 0.052
positive regulation of mitotic sister chromatid separation GO:1901970 2 0.052
regulation of cellular catabolic process GO:0031329 242 0.052
amine metabolic process GO:0009308 45 0.051
positive regulation of cellular amine metabolic process GO:0033240 5 0.051
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.049
cell division GO:0051301 120 0.049
negative regulation of protein metabolic process GO:0051248 282 0.049
male meiosis GO:0007140 37 0.048
dna recombination GO:0006310 92 0.047
protein polymerization GO:0051258 57 0.046
protein processing GO:0016485 163 0.046
peptidyl amino acid modification GO:0018193 336 0.046
protein catabolic process GO:0030163 221 0.044
ribonucleoside metabolic process GO:0009119 245 0.044
protein ubiquitination GO:0016567 171 0.044
organic cyclic compound catabolic process GO:1901361 295 0.044
regulation of cell cycle GO:0051726 281 0.043
negative regulation of molecular function GO:0044092 258 0.042
ribonucleotide metabolic process GO:0009259 291 0.042
purine ribonucleotide metabolic process GO:0009150 290 0.042
cellular amino acid metabolic process GO:0006520 103 0.041
protein modification by small protein conjugation GO:0032446 187 0.041
mitotic cytokinesis GO:0000281 4 0.041
asymmetric stem cell division GO:0098722 3 0.040
lateral inhibition GO:0046331 1 0.040
metaphase plate congression GO:0051310 2 0.039
purine nucleoside catabolic process GO:0006152 205 0.039
cellular ketone metabolic process GO:0042180 84 0.038
regulation of protein processing GO:0070613 96 0.037
regulation of cellular ketone metabolic process GO:0010565 66 0.036
negative regulation of phosphorus metabolic process GO:0010563 184 0.036
purine containing compound metabolic process GO:0072521 311 0.035
cellular macromolecule catabolic process GO:0044265 206 0.035
cellular nitrogen compound catabolic process GO:0044270 280 0.034
nucleoside catabolic process GO:0009164 206 0.034
regulation of chromosome organization GO:0033044 83 0.034
positive regulation of mitotic metaphase anaphase transition GO:0045842 2 0.034
regulation of cell cycle process GO:0010564 160 0.034
purine nucleotide metabolic process GO:0006163 302 0.034
regulation of transferase activity GO:0051338 263 0.033
nucleobase containing small molecule metabolic process GO:0055086 352 0.033
purine ribonucleoside catabolic process GO:0046130 205 0.033
positive regulation of protein modification process GO:0031401 299 0.033
protein localization to organelle GO:0033365 185 0.033
nucleoside phosphate catabolic process GO:1901292 222 0.033
covalent chromatin modification GO:0016569 163 0.032
positive regulation of protein phosphorylation GO:0001934 242 0.032
spermatogenesis GO:0007283 284 0.032
chromatin modification GO:0016568 187 0.032
carbohydrate derivative catabolic process GO:1901136 231 0.032
organelle localization GO:0051640 179 0.031
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.030
regulation of protein kinase activity GO:0045859 232 0.030
nucleotide metabolic process GO:0009117 332 0.030
spindle assembly involved in mitosis GO:0090307 4 0.029
purine containing compound catabolic process GO:0072523 213 0.029
ribonucleoside triphosphate catabolic process GO:0009203 199 0.029
positive regulation of protein kinase activity GO:0045860 144 0.028
mitotic cell cycle GO:0000278 195 0.028
nucleoside metabolic process GO:0009116 246 0.028
protein maturation GO:0051604 176 0.027
synaptic transmission GO:0007268 329 0.027
mitotic cell cycle process GO:1903047 159 0.027
cation transport GO:0006812 399 0.027
modification dependent protein catabolic process GO:0019941 133 0.027
nucleoside phosphate metabolic process GO:0006753 338 0.026
purine nucleoside triphosphate metabolic process GO:0009144 226 0.026
proteasomal protein catabolic process GO:0010498 98 0.026
positive regulation of cell division GO:0051781 31 0.026
ribonucleoside triphosphate metabolic process GO:0009199 220 0.026
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.026
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.026
cellular homeostasis GO:0019725 240 0.026
negative regulation of cell proliferation GO:0008285 296 0.026
regulation of proteolysis GO:0030162 164 0.025
endocytosis GO:0006897 168 0.024
metaphase anaphase transition of mitotic cell cycle GO:0007091 9 0.024
positive regulation of metaphase anaphase transition of cell cycle GO:1902101 2 0.024
aromatic compound catabolic process GO:0019439 286 0.024
negative regulation of protein modification process GO:0031400 163 0.024
regulation of chromatin silencing GO:0031935 2 0.024
nucleoside triphosphate catabolic process GO:0009143 205 0.023
negative regulation of proteolysis GO:0045861 74 0.023
purine ribonucleotide catabolic process GO:0009154 208 0.023
nitrogen compound transport GO:0071705 271 0.023
double strand break repair GO:0006302 48 0.023
sister chromatid segregation GO:0000819 20 0.023
transmembrane transport GO:0055085 412 0.023
regulation of neuron differentiation GO:0045664 281 0.023
purine nucleoside triphosphate catabolic process GO:0009146 203 0.022
cleavage furrow formation GO:0036089 2 0.022
synaptonemal complex organization GO:0070193 15 0.022
regulation of cytokine production GO:0001817 266 0.021
regulation of protein maturation GO:1903317 96 0.021
regulation of secretion by cell GO:1903530 249 0.021
peptidyl serine phosphorylation GO:0018105 74 0.021
gland development GO:0048732 330 0.021
ribose phosphate metabolic process GO:0019693 291 0.021
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.021
cell fate commitment GO:0045165 210 0.021
regulation of mitotic cell cycle phase transition GO:1901990 73 0.020
gene silencing GO:0016458 38 0.020
regulation of secretion GO:0051046 274 0.020
histone modification GO:0016570 159 0.020
regulation of kinase activity GO:0043549 249 0.020
positive regulation of transferase activity GO:0051347 167 0.020
organonitrogen compound catabolic process GO:1901565 264 0.020
meiosis i GO:0007127 60 0.020
purine nucleotide catabolic process GO:0006195 211 0.020
g1 s transition of mitotic cell cycle GO:0000082 57 0.020
negative regulation of phosphate metabolic process GO:0045936 184 0.020
lymphocyte differentiation GO:0030098 242 0.019
positive regulation of organelle organization GO:0010638 128 0.019
protein complex disassembly GO:0043241 40 0.019
mapk cascade GO:0000165 281 0.019
regulation of cell projection organization GO:0031344 206 0.019
ubiquitin dependent protein catabolic process GO:0006511 129 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.019
regulation of homeostatic process GO:0032844 182 0.019
regulation of protein transport GO:0051223 163 0.019
negative regulation of cellular catabolic process GO:0031330 47 0.019
small gtpase mediated signal transduction GO:0007264 97 0.019
negative regulation of chromatin silencing GO:0031936 1 0.019
regulation of mrna processing GO:0050684 41 0.019
base excision repair gap filling GO:0006287 3 0.019
maintenance of location GO:0051235 89 0.018
reactive oxygen species metabolic process GO:0072593 84 0.018
regulation of mitotic cell cycle GO:0007346 126 0.018
oogenesis GO:0048477 56 0.018
positive regulation of cellular catabolic process GO:0031331 148 0.018
ribonucleoside catabolic process GO:0042454 206 0.018
chromosome separation GO:0051304 14 0.018
anatomical structure homeostasis GO:0060249 145 0.018
leukocyte differentiation GO:0002521 342 0.018
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.018
cell cycle g1 s phase transition GO:0044843 57 0.018
cell type specific apoptotic process GO:0097285 268 0.018
positive regulation of nervous system development GO:0051962 221 0.018
dna replication GO:0006260 52 0.017
regulation of reactive oxygen species metabolic process GO:2000377 40 0.017
fertilization GO:0009566 127 0.017
negative regulation of phosphorylation GO:0042326 166 0.017
intracellular protein transport GO:0006886 204 0.017
mitotic sister chromatid cohesion GO:0007064 1 0.017
response to organonitrogen compound GO:0010243 246 0.017
positive regulation of cell cycle GO:0045787 92 0.017
regulation of lymphocyte activation GO:0051249 240 0.017
regulation of cell division GO:0051302 76 0.017
regulation of cytoplasmic transport GO:1903649 112 0.017
protein localization to chromosome centromeric region GO:0071459 1 0.017
establishment of organelle localization GO:0051656 122 0.016
response to inorganic substance GO:0010035 96 0.016
mitotic sister chromatid segregation GO:0000070 14 0.016
ion transmembrane transport GO:0034220 361 0.016
positive regulation of nuclear division GO:0051785 27 0.016
dendrite development GO:0016358 115 0.016
regulation of mapk cascade GO:0043408 248 0.016
regulation of cellular response to stress GO:0080135 159 0.016
asymmetric neuroblast division GO:0055059 1 0.016
regulation of cytoskeleton organization GO:0051493 122 0.016
endomembrane system organization GO:0010256 147 0.016
microtubule based process GO:0007017 236 0.016
nucleotide catabolic process GO:0009166 217 0.016
circulatory system process GO:0003013 197 0.016
regulation of cell motility GO:2000145 236 0.016
regulation of synaptic plasticity GO:0048167 87 0.015
positive regulation of cell development GO:0010720 237 0.015
nucleoside monophosphate metabolic process GO:0009123 85 0.015
stem cell differentiation GO:0048863 268 0.015
multicellular organismal homeostasis GO:0048871 164 0.015
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 31 0.015
regulation of microtubule cytoskeleton organization GO:0070507 37 0.015
purine nucleoside metabolic process GO:0042278 241 0.015
cellular lipid metabolic process GO:0044255 323 0.015
negative regulation of cellular component organization GO:0051129 194 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.015
muscle tissue development GO:0060537 308 0.015
ras protein signal transduction GO:0007265 77 0.015
cellular protein complex assembly GO:0043623 116 0.015
positive regulation of mitosis GO:0045840 14 0.015
posttranscriptional regulation of gene expression GO:0010608 155 0.014
myeloid cell differentiation GO:0030099 233 0.014
negative regulation of organelle organization GO:0010639 90 0.014
ribonucleoside monophosphate metabolic process GO:0009161 80 0.014
forebrain development GO:0030900 302 0.014
response to radiation GO:0009314 165 0.014
atp catabolic process GO:0006200 55 0.014
rhythmic process GO:0048511 174 0.014
chromosome movement towards spindle pole GO:0051305 3 0.014
ribonucleotide catabolic process GO:0009261 208 0.014
chromosome organization involved in meiosis GO:0070192 39 0.014
glycosyl compound catabolic process GO:1901658 206 0.014
apoptotic signaling pathway GO:0097190 306 0.014
regulation of hydrolase activity GO:0051336 246 0.014
meiosis ii GO:0007135 7 0.014
regulation of protein catabolic process GO:0042176 108 0.014
regulation of defense response GO:0031347 233 0.014
hematopoietic progenitor cell differentiation GO:0002244 143 0.014
glycosyl compound metabolic process GO:1901657 246 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.013
blood circulation GO:0008015 195 0.013
female meiotic division GO:0007143 21 0.013
regulation of chromosome segregation GO:0051983 21 0.013
carbohydrate metabolic process GO:0005975 230 0.013
regulation of protein localization GO:0032880 231 0.013
inflammatory response GO:0006954 244 0.013
spindle assembly GO:0051225 13 0.013
t cell activation GO:0042110 289 0.013
spindle assembly involved in female meiosis GO:0007056 3 0.013
cytoplasmic transport GO:0016482 234 0.013
microtubule cytoskeleton organization GO:0000226 157 0.013
nucleoside monophosphate catabolic process GO:0009125 59 0.013
negative regulation of cell development GO:0010721 169 0.013
ossification GO:0001503 216 0.013
regulation of hormone levels GO:0010817 211 0.013
rho protein signal transduction GO:0007266 32 0.013
positive regulation of exit from mitosis GO:0031536 1 0.013
positive regulation of mitotic cell cycle GO:0045931 41 0.013
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 23 0.013
response to oxidative stress GO:0006979 123 0.013
homeostasis of number of cells GO:0048872 210 0.013
purine nucleoside monophosphate catabolic process GO:0009128 58 0.013
regulation of protein serine threonine kinase activity GO:0071900 157 0.012
germ cell development GO:0007281 185 0.012
positive regulation of protein catabolic process GO:0045732 60 0.012
microtubule depolymerization GO:0007019 15 0.012
negative regulation of protein maturation GO:1903318 79 0.012
cytokine production GO:0001816 319 0.012
stem cell proliferation GO:0072089 117 0.012
positive regulation of cell death GO:0010942 224 0.012
regulation of nucleotide catabolic process GO:0030811 122 0.012
cation transmembrane transport GO:0098655 266 0.012
purine nucleoside monophosphate metabolic process GO:0009126 81 0.012
regulation of spindle organization GO:0090224 2 0.012
negative regulation of cellular amine metabolic process GO:0033239 1 0.012
positive regulation of programmed cell death GO:0043068 218 0.012
membrane organization GO:0061024 245 0.012
regulation of binding GO:0051098 111 0.012
negative regulation of immune system process GO:0002683 209 0.012
atp metabolic process GO:0046034 75 0.012
chromatin disassembly GO:0031498 1 0.012
dna endoreduplication GO:0042023 4 0.012
regulation of mitotic sister chromatid segregation GO:0033047 12 0.012
nuclear dna replication GO:0033260 3 0.012
cytokinetic process GO:0032506 2 0.012
locomotory behavior GO:0007626 195 0.012
immune effector process GO:0002252 321 0.011
divalent metal ion transport GO:0070838 172 0.011
regulation of cell cycle phase transition GO:1901987 77 0.011
cellular response to cytokine stimulus GO:0071345 189 0.011
cell adhesion GO:0007155 329 0.011
inorganic ion transmembrane transport GO:0098660 234 0.011
striated muscle tissue development GO:0014706 293 0.011
guanosine containing compound catabolic process GO:1901069 144 0.011
chromatin silencing GO:0006342 15 0.011
spindle assembly involved in meiosis GO:0090306 4 0.011
cellular component assembly involved in morphogenesis GO:0010927 139 0.011
innate immune response GO:0045087 157 0.011
regulation of proteasomal protein catabolic process GO:0061136 46 0.011
response to light stimulus GO:0009416 135 0.011
regulation of microtubule based process GO:0032886 52 0.011
cellular chemical homeostasis GO:0055082 215 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.011
monocarboxylic acid metabolic process GO:0032787 191 0.011
inorganic cation transmembrane transport GO:0098662 207 0.011
regulation of inflammatory response GO:0050727 147 0.011
regulation of cellular protein catabolic process GO:1903362 61 0.011
cellularization GO:0007349 1 0.011
negative regulation of microtubule polymerization GO:0031115 2 0.011
hatching GO:0035188 4 0.011
oxidation reduction process GO:0055114 342 0.011
sister chromatid cohesion GO:0007062 12 0.011
stem cell development GO:0048864 219 0.011
dephosphorylation GO:0016311 129 0.011
positive regulation of cell cycle process GO:0090068 61 0.011
regulation of establishment of protein localization GO:0070201 181 0.011
organic hydroxy compound metabolic process GO:1901615 203 0.011
protein targeting GO:0006605 143 0.011
regulation of anatomical structure size GO:0090066 178 0.011
negative regulation of protein phosphorylation GO:0001933 126 0.011
peptide hormone secretion GO:0030072 109 0.011
microtubule polymerization GO:0046785 12 0.011
amide transport GO:0042886 138 0.011
b cell activation GO:0042113 161 0.011
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.011
regulation of cell activation GO:0050865 289 0.010
muscle cell differentiation GO:0042692 261 0.010
modification dependent macromolecule catabolic process GO:0043632 133 0.010
cell maturation GO:0048469 127 0.010
actin cytoskeleton organization GO:0030036 220 0.010
regulation of purine nucleotide metabolic process GO:1900542 169 0.010
tube closure GO:0060606 91 0.010
developmental maturation GO:0021700 193 0.010
adaptive immune response GO:0002250 155 0.010
blood vessel morphogenesis GO:0048514 285 0.010
lipid biosynthetic process GO:0008610 179 0.010
translesion synthesis GO:0019985 1 0.010
response to organic cyclic compound GO:0014070 198 0.010
hormone secretion GO:0046879 128 0.010
rna processing GO:0006396 105 0.010
carbohydrate homeostasis GO:0033500 128 0.010
gtp metabolic process GO:0046039 144 0.010
signal transduction by p53 class mediator GO:0072331 51 0.010
leukocyte mediated immunity GO:0002443 174 0.010
divalent inorganic cation transport GO:0072511 178 0.010

Espl1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.043
disease of cellular proliferation DOID:14566 0 0.043
organ system cancer DOID:0050686 0 0.043
gastrointestinal system cancer DOID:3119 0 0.036
large intestine cancer DOID:5672 0 0.024
intestinal cancer DOID:10155 0 0.024
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.016
disease of metabolism DOID:0014667 0 0.010
inherited metabolic disorder DOID:655 0 0.010
colorectal cancer DOID:9256 0 0.010