Mus musculus

31 known processes

Prm2

protamine 2

(Aliases: AI528784,Prm-2)

Prm2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
alcohol metabolic process GO:0006066 116 0.236
amine metabolic process GO:0009308 45 0.107
cellular amine metabolic process GO:0044106 44 0.101
rho protein signal transduction GO:0007266 32 0.097
cellular ketone metabolic process GO:0042180 84 0.095
cytokine production GO:0001816 319 0.078
regulation of endopeptidase activity GO:0052548 89 0.078
lipid biosynthetic process GO:0008610 179 0.076
sensory perception GO:0007600 245 0.075
protein processing GO:0016485 163 0.074
negative regulation of protein metabolic process GO:0051248 282 0.073
organic hydroxy compound metabolic process GO:1901615 203 0.072
actin cytoskeleton organization GO:0030036 220 0.070
regulation of cellular ketone metabolic process GO:0010565 66 0.067
extracellular structure organization GO:0043062 148 0.066
steroid metabolic process GO:0008202 119 0.063
regulation of cellular amine metabolic process GO:0033238 20 0.062
protein catabolic process GO:0030163 221 0.062
small molecule biosynthetic process GO:0044283 132 0.061
cellular amino acid metabolic process GO:0006520 103 0.060
fatty acid metabolic process GO:0006631 121 0.059
directional locomotion GO:0033058 3 0.058
negative regulation of cellular protein metabolic process GO:0032269 247 0.057
positive regulation of cellular amine metabolic process GO:0033240 5 0.057
organic hydroxy compound biosynthetic process GO:1901617 77 0.054
binding of sperm to zona pellucida GO:0007339 34 0.053
non canonical wnt signaling pathway via jnk cascade GO:0038031 3 0.051
regulation of kinase activity GO:0043549 249 0.046
regulation of cellular amino acid metabolic process GO:0006521 5 0.045
macromolecule catabolic process GO:0009057 281 0.045
regulation of tube size GO:0035150 57 0.045
carbohydrate derivative biosynthetic process GO:1901137 183 0.044
regulation of rho gtpase activity GO:0032319 58 0.042
male gonad development GO:0008584 88 0.042
gland development GO:0048732 330 0.042
male sex differentiation GO:0046661 109 0.041
negative regulation of cellular amine metabolic process GO:0033239 1 0.041
epithelial cell development GO:0002064 159 0.041
regulation of proteolysis GO:0030162 164 0.041
regulation of protein kinase activity GO:0045859 232 0.040
non canonical wnt signaling pathway via mapk cascade GO:0038030 3 0.040
glycosyl compound catabolic process GO:1901658 206 0.039
monocarboxylic acid metabolic process GO:0032787 191 0.039
regulation of mapk cascade GO:0043408 248 0.039
respiratory system development GO:0060541 190 0.039
positive regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation GO:2000081 1 0.037
regulation of interleukin 8 production GO:0032677 3 0.036
small gtpase mediated signal transduction GO:0007264 97 0.036
negative regulation of protein modification process GO:0031400 163 0.036
regulation of hydrolase activity GO:0051336 246 0.036
peptidyl serine modification GO:0018209 83 0.036
spermatogenesis GO:0007283 284 0.036
positive regulation of secretion GO:0051047 130 0.035
regulation of protein maturation GO:1903317 96 0.035
male gamete generation GO:0048232 285 0.035
cellular lipid metabolic process GO:0044255 323 0.035
cell type specific apoptotic process GO:0097285 268 0.034
glycoprotein metabolic process GO:0009100 116 0.034
regulation of eosinophil migration GO:2000416 2 0.034
leukocyte differentiation GO:0002521 342 0.034
regulation of cell migration GO:0030334 219 0.034
dna metabolic process GO:0006259 303 0.033
ubiquitin dependent smad protein catabolic process GO:0030579 2 0.033
cell cell recognition GO:0009988 44 0.033
cell recognition GO:0008037 83 0.033
regulation of hormone levels GO:0010817 211 0.033
wnt signaling pathway GO:0016055 188 0.032
positive regulation of apoptotic process GO:0043065 217 0.032
regulation of defense response GO:0031347 233 0.032
cell substrate adhesion GO:0031589 130 0.032
regulation of rho protein signal transduction GO:0035023 71 0.032
alcohol biosynthetic process GO:0046165 43 0.031
sperm egg recognition GO:0035036 37 0.030
blood vessel morphogenesis GO:0048514 285 0.030
nucleobase containing small molecule metabolic process GO:0055086 352 0.030
regulation of cell activation GO:0050865 289 0.030
regulation of lipid biosynthetic process GO:0046890 54 0.030
negative regulation of endopeptidase activity GO:0010951 44 0.029
regulation of cellular response to stress GO:0080135 159 0.029
kidney epithelium development GO:0072073 121 0.028
lipid transport GO:0006869 98 0.028
posttranscriptional regulation of gene expression GO:0010608 155 0.028
positive regulation of interleukin 8 production GO:0032757 2 0.028
purine ribonucleotide metabolic process GO:0009150 290 0.028
negative regulation of hydrolase activity GO:0051346 71 0.028
ribonucleotide catabolic process GO:0009261 208 0.028
inflammatory response GO:0006954 244 0.028
protein maturation GO:0051604 176 0.028
interleukin 8 secretion GO:0072606 3 0.027
epidermis development GO:0008544 187 0.027
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.027
organophosphate biosynthetic process GO:0090407 122 0.027
urogenital system development GO:0001655 261 0.027
lymphocyte differentiation GO:0030098 242 0.027
interleukin 8 production GO:0032637 4 0.027
negative regulation of epithelial cell proliferation GO:0050680 64 0.027
ureteric bud development GO:0001657 94 0.026
ras protein signal transduction GO:0007265 77 0.026
protein localization to plasma membrane GO:0072659 57 0.026
response to acid chemical GO:0001101 111 0.026
negative chemotaxis GO:0050919 14 0.026
purine nucleotide metabolic process GO:0006163 302 0.026
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.026
nucleoside phosphate metabolic process GO:0006753 338 0.026
nucleotide metabolic process GO:0009117 332 0.025
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.025
cell adhesion GO:0007155 329 0.025
positive regulation of programmed cell death GO:0043068 218 0.025
establishment of protein localization to membrane GO:0090150 54 0.025
carbohydrate homeostasis GO:0033500 128 0.025
germ cell development GO:0007281 185 0.024
fertilization GO:0009566 127 0.024
regulation of organelle organization GO:0033043 289 0.024
extracellular matrix organization GO:0030198 147 0.024
actin filament organization GO:0007015 113 0.024
regulation of secretion by cell GO:1903530 249 0.024
stem cell differentiation GO:0048863 268 0.024
response to parathyroid hormone GO:0071107 3 0.023
regulation of protein processing GO:0070613 96 0.023
adaptive immune response GO:0002250 155 0.023
protein localization to membrane GO:0072657 108 0.023
lipid localization GO:0010876 126 0.023
regulation of system process GO:0044057 200 0.023
membrane organization GO:0061024 245 0.022
cholesterol metabolic process GO:0008203 56 0.022
neuron death GO:0070997 154 0.022
microtubule based process GO:0007017 236 0.022
ribonucleotide metabolic process GO:0009259 291 0.022
androgen biosynthetic process GO:0006702 4 0.021
retinoid metabolic process GO:0001523 24 0.021
positive regulation of cell death GO:0010942 224 0.021
response to insulin GO:0032868 100 0.021
negative regulation of molecular function GO:0044092 258 0.021
negative regulation of protein maturation GO:1903318 79 0.021
developmental growth involved in morphogenesis GO:0060560 138 0.021
myoblast differentiation involved in skeletal muscle regeneration GO:0014835 3 0.021
regulation of cardioblast differentiation GO:0051890 3 0.021
nucleoside triphosphate catabolic process GO:0009143 205 0.021
negative regulation of proteolysis GO:0045861 74 0.021
cell matrix adhesion GO:0007160 68 0.021
negative regulation of phosphorylation GO:0042326 166 0.020
lipoprotein metabolic process GO:0042157 43 0.020
organophosphate catabolic process GO:0046434 232 0.020
maintenance of location GO:0051235 89 0.020
fatty acid biosynthetic process GO:0006633 41 0.020
carbohydrate metabolic process GO:0005975 230 0.020
regulation of purine nucleotide catabolic process GO:0033121 122 0.020
calcium ion transport GO:0006816 159 0.020
negative regulation of protein phosphorylation GO:0001933 126 0.020
negative regulation of cytokine production GO:0001818 84 0.020
purine containing compound metabolic process GO:0072521 311 0.019
intrinsic apoptotic signaling pathway GO:0097193 132 0.019
regulation of ras gtpase activity GO:0032318 88 0.019
skin development GO:0043588 220 0.019
negative regulation of cell proliferation GO:0008285 296 0.019
muscle tissue development GO:0060537 308 0.019
response to peptide GO:1901652 136 0.019
glycosylation GO:0070085 62 0.019
cop9 signalosome assembly GO:0010387 2 0.019
canonical wnt signaling pathway involved in heart development GO:0061316 3 0.019
wnt signaling pathway calcium modulating pathway GO:0007223 2 0.019
steroid biosynthetic process GO:0006694 47 0.018
stress activated protein kinase signaling cascade GO:0031098 81 0.018
negative regulation of gastrulation GO:2000542 3 0.018
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.018
regulation of transforming growth factor beta2 production GO:0032909 2 0.018
hexose biosynthetic process GO:0019319 39 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.018
organonitrogen compound biosynthetic process GO:1901566 192 0.018
regulation of cytokine production GO:0001817 266 0.018
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.018
modification dependent protein catabolic process GO:0019941 133 0.018
nucleotide catabolic process GO:0009166 217 0.018
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.018
regulation of membrane potential GO:0042391 192 0.018
transforming growth factor beta2 production GO:0032906 2 0.017
positive regulation of apoptotic process involved in mammary gland involution GO:0060058 4 0.017
regulation of inflammatory response GO:0050727 147 0.017
endomembrane system organization GO:0010256 147 0.017
regulation of canonical wnt signaling pathway GO:0060828 82 0.017
protein modification by small protein conjugation or removal GO:0070647 207 0.017
sterol metabolic process GO:0016125 58 0.017
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 1 0.017
molting cycle GO:0042303 90 0.017
neuromuscular process GO:0050905 99 0.017
spermatid development GO:0007286 108 0.017
nucleoside phosphate catabolic process GO:1901292 222 0.017
ribose phosphate metabolic process GO:0019693 291 0.017
microtubule cytoskeleton organization GO:0000226 157 0.017
cellular chemical homeostasis GO:0055082 215 0.017
hepaticobiliary system development GO:0061008 67 0.017
neural tube patterning GO:0021532 43 0.017
response to extracellular stimulus GO:0009991 127 0.016
positive regulation of stress activated mapk cascade GO:0032874 48 0.016
purine nucleoside triphosphate metabolic process GO:0009144 226 0.016
regulation of lymphocyte activation GO:0051249 240 0.016
regulation of interleukin 8 secretion GO:2000482 2 0.016
positive regulation of peptidyl serine phosphorylation GO:0033138 25 0.016
striated muscle tissue development GO:0014706 293 0.016
cellular response to cadmium ion GO:0071276 3 0.016
regulation of peptidyl serine phosphorylation GO:0033135 39 0.016
chromatin organization GO:0006325 206 0.016
gas homeostasis GO:0033483 3 0.016
labyrinthine layer development GO:0060711 49 0.016
telencephalon development GO:0021537 186 0.016
positive regulation of nervous system development GO:0051962 221 0.016
purine ribonucleoside catabolic process GO:0046130 205 0.016
negative regulation of protein processing GO:0010955 79 0.016
regulation of purine nucleotide metabolic process GO:1900542 169 0.016
regulation of testosterone biosynthetic process GO:2000224 2 0.016
t cell activation GO:0042110 289 0.015
establishment of organ orientation GO:0048561 1 0.015
positive regulation of transforming growth factor beta2 production GO:0032915 2 0.015
development of primary male sexual characteristics GO:0046546 88 0.015
negative regulation of intracellular signal transduction GO:1902532 167 0.015
response to organic cyclic compound GO:0014070 198 0.015
regulation of leukocyte differentiation GO:1902105 159 0.015
regulation of transferase activity GO:0051338 263 0.015
liver development GO:0001889 66 0.015
epithelial tube morphogenesis GO:0060562 303 0.015
positive regulation of cell development GO:0010720 237 0.015
negative regulation of phosphate metabolic process GO:0045936 184 0.015
regulation of cell cell adhesion mediated by cadherin GO:2000047 2 0.015
respiratory tube development GO:0030323 167 0.015
regulation of phospholipid biosynthetic process GO:0071071 3 0.015
canonical wnt signaling pathway involved in regulation of cell proliferation GO:0044340 3 0.015
labyrinthine layer blood vessel development GO:0060716 21 0.015
cation transport GO:0006812 399 0.015
rhythmic process GO:0048511 174 0.015
epithelial cell migration GO:0010631 63 0.015
purine nucleoside catabolic process GO:0006152 205 0.015
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.015
cellular response to inorganic substance GO:0071241 37 0.014
lung development GO:0030324 164 0.014
dendrite development GO:0016358 115 0.014
regulation of metal ion transport GO:0010959 106 0.014
somatotropin secreting cell differentiation GO:0060126 4 0.014
response to peptide hormone GO:0043434 127 0.014
epithelial cell proliferation GO:0050673 174 0.014
regulation of vitamin metabolic process GO:0030656 3 0.014
intracellular protein transport GO:0006886 204 0.014
regulation of secretion GO:0051046 274 0.014
cellular response to lipid GO:0071396 145 0.014
reactive oxygen species metabolic process GO:0072593 84 0.014
positive regulation of mapk cascade GO:0043410 170 0.014
proteasomal protein catabolic process GO:0010498 98 0.014
positive regulation of rho gtpase activity GO:0032321 41 0.014
regulation of steroid metabolic process GO:0019218 39 0.014
lens morphogenesis in camera type eye GO:0002089 24 0.014
b cell activation GO:0042113 161 0.014
regulation of cytoskeleton organization GO:0051493 122 0.014
circulatory system process GO:0003013 197 0.014
peptidyl amino acid modification GO:0018193 336 0.014
nucleoside metabolic process GO:0009116 246 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.014
positive regulation of anagen GO:0051885 1 0.014
nucleoside catabolic process GO:0009164 206 0.014
regulation of cysteine type endopeptidase activity GO:2000116 65 0.014
regulation of organ morphogenesis GO:2000027 144 0.014
response to inorganic substance GO:0010035 96 0.014
negative regulation of immune system process GO:0002683 209 0.014
positive regulation of transferase activity GO:0051347 167 0.014
nucleosome positioning GO:0016584 4 0.014
peptidyl serine phosphorylation GO:0018105 74 0.014
nephron epithelium development GO:0072009 92 0.014
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.013
regulation of mitotic cell cycle phase transition GO:1901990 73 0.013
apoptotic signaling pathway GO:0097190 306 0.013
regulation of response to wounding GO:1903034 189 0.013
positive regulation of homeostatic process GO:0032846 64 0.013
spemann organizer formation GO:0060061 2 0.013
single fertilization GO:0007338 82 0.013
midgut development GO:0007494 4 0.013
meiotic cell cycle GO:0051321 122 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.013
jnk cascade GO:0007254 72 0.013
regulation of peptidase activity GO:0052547 96 0.013
regulation of stress activated mapk cascade GO:0032872 69 0.013
negative regulation of peptidase activity GO:0010466 46 0.013
heart induction GO:0003129 2 0.013
regulation of cell cycle phase transition GO:1901987 77 0.013
positive regulation of proteolysis GO:0045862 85 0.013
regulation of nucleotide metabolic process GO:0006140 169 0.013
carbohydrate biosynthetic process GO:0016051 74 0.013
purine containing compound catabolic process GO:0072523 213 0.013
renal vesicle induction GO:0072034 3 0.013
ubiquitin dependent protein catabolic process GO:0006511 129 0.013
regulation of proteasomal protein catabolic process GO:0061136 46 0.013
glucose homeostasis GO:0042593 128 0.013
cellular response to hormone stimulus GO:0032870 150 0.013
methylation GO:0032259 134 0.013
cellular macromolecule catabolic process GO:0044265 206 0.013
type b pancreatic cell proliferation GO:0044342 10 0.013
cholesterol homeostasis GO:0042632 44 0.013
regulation of systemic arterial blood pressure by hormone GO:0001990 25 0.013
negative regulation of neuron apoptotic process GO:0043524 92 0.013
myeloid leukocyte differentiation GO:0002573 119 0.013
planar cell polarity pathway involved in heart morphogenesis GO:0061346 3 0.012
negative regulation of phagocytosis GO:0050765 4 0.012
response to organonitrogen compound GO:0010243 246 0.012
regulation of actin cytoskeleton organization GO:0032956 84 0.012
negative regulation of wnt signaling pathway GO:0030178 73 0.012
cation homeostasis GO:0055080 212 0.012
adult behavior GO:0030534 135 0.012
regulation of protein kinase c activity GO:1900019 1 0.012
renal inner medulla development GO:0072053 3 0.012
mapk cascade GO:0000165 281 0.012
wound healing GO:0042060 157 0.012
peripheral nervous system development GO:0007422 53 0.012
protein modification by small protein conjugation GO:0032446 187 0.012
blood coagulation GO:0007596 76 0.012
ribonucleoside metabolic process GO:0009119 245 0.012
covalent chromatin modification GO:0016569 163 0.012
lymphocyte mediated immunity GO:0002449 139 0.012
spemann organizer formation at the anterior end of the primitive streak GO:0060064 1 0.012
regulation of carbohydrate metabolic process GO:0006109 75 0.012
oxidation reduction process GO:0055114 342 0.012
ribonucleoside triphosphate catabolic process GO:0009203 199 0.012
maintenance of cell number GO:0098727 3 0.012
cell migration involved in heart formation GO:0060974 1 0.012
regulation of cellular protein catabolic process GO:1903362 61 0.012
regulation of jnk cascade GO:0046328 62 0.012
development of primary sexual characteristics GO:0045137 143 0.012
cell growth GO:0016049 130 0.012
regulation of cellular component biogenesis GO:0044087 181 0.012
regulation of glutamate metabolic process GO:2000211 1 0.012
muscle cell differentiation GO:0042692 261 0.012
response to vitamin a GO:0033189 1 0.012
oxygen homeostasis GO:0032364 2 0.012
mammary gland epithelium development GO:0061180 65 0.012
glycoprotein biosynthetic process GO:0009101 89 0.012
cellular protein catabolic process GO:0044257 155 0.012
purine ribonucleotide catabolic process GO:0009154 208 0.012
regulation of wnt signaling pathway GO:0030111 123 0.012
positive regulation of protein kinase c activity GO:1900020 1 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.012
heterocycle catabolic process GO:0046700 280 0.012
digestive system development GO:0055123 200 0.012
positive regulation of gtp catabolic process GO:0033126 85 0.012
response to lipopolysaccharide GO:0032496 128 0.012
positive regulation of branching involved in lung morphogenesis GO:0061047 4 0.011
cerebellum development GO:0021549 77 0.011
purine nucleotide catabolic process GO:0006195 211 0.011
leukocyte proliferation GO:0070661 172 0.011
regulation of striated muscle cell differentiation GO:0051153 81 0.011
wnt signaling pathway involved in heart development GO:0003306 8 0.011
neuron apoptotic process GO:0051402 142 0.011
stress activated mapk cascade GO:0051403 80 0.011
positive regulation of cytokine production GO:0001819 174 0.011
purine ribonucleoside metabolic process GO:0046128 241 0.011
response to nutrient levels GO:0031667 109 0.011
fat soluble vitamin biosynthetic process GO:0042362 4 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.011
regulation of muscle tissue development GO:1901861 97 0.011
guanosine containing compound metabolic process GO:1901068 144 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.011
regulation of actin filament based process GO:0032970 99 0.011
tube formation GO:0035148 140 0.011
cellular component assembly involved in morphogenesis GO:0010927 139 0.011
appendage development GO:0048736 166 0.011
vitamin d biosynthetic process GO:0042368 3 0.011
positive regulation of nucleotide metabolic process GO:0045981 114 0.011
regulation of asymmetric cell division GO:0009786 4 0.011
dephosphorylation GO:0016311 129 0.011
hormone metabolic process GO:0042445 86 0.011
macromolecule glycosylation GO:0043413 55 0.011
stem cell maintenance GO:0019827 130 0.011
cellular response to peptide hormone stimulus GO:0071375 92 0.011
ossification GO:0001503 216 0.011
planar cell polarity pathway involved in pericardium morphogenesis GO:0061354 2 0.011
ameboidal type cell migration GO:0001667 128 0.011
negative regulation of testosterone biosynthetic process GO:2000225 1 0.011
protein targeting GO:0006605 143 0.011
hair cycle GO:0042633 90 0.011
response to metal ion GO:0010038 47 0.011
regulation of morphogenesis of a branching structure GO:0060688 53 0.011
testosterone biosynthetic process GO:0061370 2 0.011
mitotic cytokinesis GO:0000281 4 0.011
action potential GO:0001508 78 0.011
divalent inorganic cation homeostasis GO:0072507 138 0.010
positive regulation of protein phosphorylation GO:0001934 242 0.010
developmental maturation GO:0021700 193 0.010
central nervous system morphogenesis GO:0021551 2 0.010
regulation of cellular catabolic process GO:0031329 242 0.010
response to bile acid GO:1903412 1 0.010
organelle fission GO:0048285 170 0.010
lens development in camera type eye GO:0002088 62 0.010
negative regulation of neuron death GO:1901215 98 0.010
response to radiation GO:0009314 165 0.010
limb development GO:0060173 166 0.010
positive regulation of lymphocyte activation GO:0051251 140 0.010
cellular response to dna damage stimulus GO:0006974 207 0.010
tissue homeostasis GO:0001894 115 0.010
inclusion body assembly GO:0070841 3 0.010
modification dependent macromolecule catabolic process GO:0043632 133 0.010

Prm2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.017
disease of anatomical entity DOID:7 0 0.017
central nervous system disease DOID:331 0 0.017
disease of cellular proliferation DOID:14566 0 0.015
cancer DOID:162 0 0.014
musculoskeletal system disease DOID:17 0 0.012
connective tissue disease DOID:65 0 0.012
neurodegenerative disease DOID:1289 0 0.011
organ system cancer DOID:0050686 0 0.010