Mus musculus

0 known processes

Wdr81

WD repeat domain 81

(Aliases: BC054822,MGC32441,Gm883,mFLJ00182)

Wdr81 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
vacuole organization GO:0007033 38 0.345
transmembrane transport GO:0055085 412 0.319
ion transmembrane transport GO:0034220 361 0.238
anion transport GO:0006820 177 0.210
cation transmembrane transport GO:0098655 266 0.166
organic anion transport GO:0015711 137 0.159
autophagy GO:0006914 45 0.151
lytic vacuole organization GO:0080171 21 0.136
lysosome organization GO:0007040 21 0.132
cellular homeostasis GO:0019725 240 0.121
nitrogen compound transport GO:0071705 271 0.098
phospholipid transfer to membrane GO:0006649 2 0.096
calcium ion homeostasis GO:0055074 127 0.095
striated muscle tissue development GO:0014706 293 0.092
cellular nitrogen compound catabolic process GO:0044270 280 0.090
organic acid transport GO:0015849 101 0.089
nucleobase containing small molecule metabolic process GO:0055086 352 0.081
negative regulation of phosphorus metabolic process GO:0010563 184 0.080
Human
regulation of secretion by cell GO:1903530 249 0.073
nucleoside phosphate metabolic process GO:0006753 338 0.073
cation homeostasis GO:0055080 212 0.068
carboxylic acid transport GO:0046942 100 0.068
regulation of membrane potential GO:0042391 192 0.064
amino acid transport GO:0006865 61 0.063
purine ribonucleotide metabolic process GO:0009150 290 0.061
cellular calcium ion homeostasis GO:0006874 119 0.060
inorganic cation transmembrane transport GO:0098662 207 0.059
amine metabolic process GO:0009308 45 0.059
regulation of cellular catabolic process GO:0031329 242 0.059
ras protein signal transduction GO:0007265 77 0.058
gland development GO:0048732 330 0.057
purine containing compound metabolic process GO:0072521 311 0.057
nucleotide metabolic process GO:0009117 332 0.054
divalent inorganic cation transport GO:0072511 178 0.054
ribonucleotide metabolic process GO:0009259 291 0.052
cellular chemical homeostasis GO:0055082 215 0.051
membrane organization GO:0061024 245 0.048
negative regulation of intracellular signal transduction GO:1902532 167 0.048
regulation of homeostatic process GO:0032844 182 0.047
macromolecule catabolic process GO:0009057 281 0.046
regulation of purine nucleotide metabolic process GO:1900542 169 0.046
carbohydrate derivative biosynthetic process GO:1901137 183 0.045
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.044
cellular amine metabolic process GO:0044106 44 0.044
purine ribonucleotide catabolic process GO:0009154 208 0.044
purine nucleoside triphosphate metabolic process GO:0009144 226 0.042
cellular lipid metabolic process GO:0044255 323 0.041
multicellular organismal homeostasis GO:0048871 164 0.041
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.040
aromatic compound catabolic process GO:0019439 286 0.039
cellular metal ion homeostasis GO:0006875 151 0.039
organic cyclic compound catabolic process GO:1901361 295 0.039
cellular ion homeostasis GO:0006873 165 0.039
carbohydrate homeostasis GO:0033500 128 0.038
macroautophagy GO:0016236 21 0.038
glycosyl compound catabolic process GO:1901658 206 0.038
nucleoside catabolic process GO:0009164 206 0.038
intracellular protein transport GO:0006886 204 0.038
muscle tissue development GO:0060537 308 0.038
inorganic ion transmembrane transport GO:0098660 234 0.038
rho protein signal transduction GO:0007266 32 0.038
glycosyl compound metabolic process GO:1901657 246 0.037
cofactor transport GO:0051181 4 0.037
visual perception GO:0007601 52 0.037
heterocycle catabolic process GO:0046700 280 0.037
small gtpase mediated signal transduction GO:0007264 97 0.036
cellular amino acid metabolic process GO:0006520 103 0.036
sensory perception GO:0007600 245 0.036
regulation of feeding behavior GO:0060259 3 0.036
response to organonitrogen compound GO:0010243 246 0.035
protein modification by small protein conjugation GO:0032446 187 0.035
purine nucleoside triphosphate catabolic process GO:0009146 203 0.035
organonitrogen compound catabolic process GO:1901565 264 0.034
rhythmic process GO:0048511 174 0.033
metal ion homeostasis GO:0055065 189 0.033
oxidation reduction process GO:0055114 342 0.033
muscle system process GO:0003012 141 0.033
purine containing compound catabolic process GO:0072523 213 0.033
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.032
anion transmembrane transport GO:0098656 71 0.032
cognition GO:0050890 149 0.032
divalent inorganic cation homeostasis GO:0072507 138 0.032
alcohol metabolic process GO:0006066 116 0.032
endocytosis GO:0006897 168 0.031
cofactor metabolic process GO:0051186 80 0.031
locomotory behavior GO:0007626 195 0.031
organonitrogen compound biosynthetic process GO:1901566 192 0.031
purine nucleotide catabolic process GO:0006195 211 0.031
ribonucleotide catabolic process GO:0009261 208 0.030
response to acid chemical GO:0001101 111 0.030
carbohydrate derivative catabolic process GO:1901136 231 0.030
cellular response to extracellular stimulus GO:0031668 81 0.030
peptide transport GO:0015833 133 0.030
maintenance of location GO:0051235 89 0.029
regionalization GO:0003002 337 0.029
mapk cascade GO:0000165 281 0.029
regulation of secretion GO:0051046 274 0.029
negative regulation of phosphate metabolic process GO:0045936 184 0.029
Human
cellular macromolecule catabolic process GO:0044265 206 0.029
purine ribonucleoside catabolic process GO:0046130 205 0.029
response to molecule of bacterial origin GO:0002237 143 0.028
organic hydroxy compound metabolic process GO:1901615 203 0.028
organophosphate catabolic process GO:0046434 232 0.028
cation transport GO:0006812 399 0.028
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.028
purine nucleotide metabolic process GO:0006163 302 0.028
positive regulation of secretion GO:0051047 130 0.027
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.027
nucleoside phosphate catabolic process GO:1901292 222 0.027
protein catabolic process GO:0030163 221 0.027
learning or memory GO:0007611 148 0.027
ribonucleoside triphosphate metabolic process GO:0009199 220 0.027
defense response to other organism GO:0098542 197 0.027
response to oxygen levels GO:0070482 62 0.027
neuromuscular process controlling balance GO:0050885 59 0.027
forebrain development GO:0030900 302 0.027
chromatin modification GO:0016568 187 0.026
ribonucleoside catabolic process GO:0042454 206 0.026
positive regulation of nucleoside metabolic process GO:0045979 91 0.026
methylation GO:0032259 134 0.026
ribose phosphate metabolic process GO:0019693 291 0.026
regulation of cytokine production GO:0001817 266 0.025
peptidyl amino acid modification GO:0018193 336 0.025
cell type specific apoptotic process GO:0097285 268 0.025
purine nucleoside catabolic process GO:0006152 205 0.025
g protein coupled receptor signaling pathway GO:0007186 243 0.025
microtubule cytoskeleton organization GO:0000226 157 0.025
purine ribonucleoside metabolic process GO:0046128 241 0.025
regulation of cytoskeleton organization GO:0051493 122 0.025
regulation of cellular response to stress GO:0080135 159 0.024
positive regulation of nucleotide metabolic process GO:0045981 114 0.024
cellular response to external stimulus GO:0071496 88 0.024
actin cytoskeleton organization GO:0030036 220 0.023
exocytosis GO:0006887 121 0.023
sequestering of calcium ion GO:0051208 18 0.023
muscle cell differentiation GO:0042692 261 0.023
regulation of engulfment of apoptotic cell GO:1901074 2 0.023
retrograde transport endosome to golgi GO:0042147 2 0.023
positive regulation of cell activation GO:0050867 158 0.023
anatomical structure homeostasis GO:0060249 145 0.023
membrane lipid metabolic process GO:0006643 53 0.022
divalent metal ion transport GO:0070838 172 0.022
single organism cell adhesion GO:0098602 156 0.022
response to starvation GO:0042594 65 0.022
neuromuscular process GO:0050905 99 0.022
regulation of cell activation GO:0050865 289 0.022
ribonucleoside triphosphate catabolic process GO:0009203 199 0.022
hydrogen transport GO:0006818 35 0.021
regulation of kinase activity GO:0043549 249 0.021
regulation of mapk cascade GO:0043408 248 0.021
lipoprotein metabolic process GO:0042157 43 0.021
respiratory system development GO:0060541 190 0.021
purine nucleoside metabolic process GO:0042278 241 0.021
sphingolipid metabolic process GO:0006665 45 0.021
regulation of ion transmembrane transport GO:0034765 119 0.021
small molecule biosynthetic process GO:0044283 132 0.021
response to oxidative stress GO:0006979 123 0.021
response to inorganic substance GO:0010035 96 0.021
regulation of mitotic cell cycle GO:0007346 126 0.021
cellular response to nutrient levels GO:0031669 64 0.021
positive regulation of phagocytosis engulfment GO:0060100 3 0.021
defecation GO:0030421 1 0.020
appendage morphogenesis GO:0035107 149 0.020
regulation of hormone secretion GO:0046883 88 0.020
multicellular organismal signaling GO:0035637 91 0.020
carbohydrate metabolic process GO:0005975 230 0.020
cellular divalent inorganic cation homeostasis GO:0072503 127 0.020
negative regulation of protein metabolic process GO:0051248 282 0.020
appendage development GO:0048736 166 0.020
glucose homeostasis GO:0042593 128 0.020
response to peptide GO:1901652 136 0.020
cytoplasmic transport GO:0016482 234 0.020
tissue remodeling GO:0048771 102 0.020
nucleoside triphosphate catabolic process GO:0009143 205 0.020
regulation of nucleotide catabolic process GO:0030811 122 0.020
detection of abiotic stimulus GO:0009582 60 0.019
dephosphorylation GO:0016311 129 0.019
Human
regulation of ion transport GO:0043269 215 0.019
nucleotide catabolic process GO:0009166 217 0.019
lipid transport GO:0006869 98 0.019
regulation of purine nucleotide catabolic process GO:0033121 122 0.019
epidermis development GO:0008544 187 0.019
regulation of cellular amine metabolic process GO:0033238 20 0.019
endocrine system development GO:0035270 98 0.019
regulation of neurotransmitter levels GO:0001505 87 0.019
regulation of nucleoside metabolic process GO:0009118 130 0.019
calcium ion transport GO:0006816 159 0.019
response to hypoxia GO:0001666 58 0.018
cellular ketone metabolic process GO:0042180 84 0.018
peptide secretion GO:0002790 114 0.018
sequestering of metal ion GO:0051238 19 0.018
nucleoside metabolic process GO:0009116 246 0.018
skeletal muscle organ development GO:0060538 163 0.018
negative regulation of cellular component organization GO:0051129 194 0.018
insulin secretion GO:0030073 89 0.018
cytokine production GO:0001816 319 0.018
glycoprotein metabolic process GO:0009100 116 0.018
calcium ion transmembrane transport GO:0070588 85 0.018
b cell activation GO:0042113 161 0.017
response to lipopolysaccharide GO:0032496 128 0.017
cellular response to acid chemical GO:0071229 68 0.017
regulation of hormone levels GO:0010817 211 0.017
cardiocyte differentiation GO:0035051 87 0.017
chromatin organization GO:0006325 206 0.017
positive regulation of hydrolase activity GO:0051345 148 0.017
regulation of nucleotide metabolic process GO:0006140 169 0.017
regulation of transmembrane transport GO:0034762 128 0.017
neural precursor cell proliferation GO:0061351 121 0.017
autophagic vacuole fusion GO:0000046 1 0.017
hindbrain development GO:0030902 128 0.017
cellular response to starvation GO:0009267 57 0.017
response to extracellular stimulus GO:0009991 127 0.016
male gamete generation GO:0048232 285 0.016
amide transport GO:0042886 138 0.016
protein processing GO:0016485 163 0.016
lung development GO:0030324 164 0.016
regulation of transferase activity GO:0051338 263 0.016
negative regulation of molecular function GO:0044092 258 0.016
Human
regulation of ras protein signal transduction GO:0046578 114 0.016
myosin filament assembly GO:0031034 2 0.016
monosaccharide metabolic process GO:0005996 106 0.016
l amino acid transport GO:0015807 32 0.016
ear development GO:0043583 200 0.015
hematopoietic progenitor cell differentiation GO:0002244 143 0.015
oocyte construction GO:0007308 2 0.015
regulation of lymphocyte activation GO:0051249 240 0.015
fatty acid metabolic process GO:0006631 121 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.015
sensory system development GO:0048880 3 0.015
positive regulation of membrane protein ectodomain proteolysis GO:0051044 3 0.015
positive regulation of cellular amine metabolic process GO:0033240 5 0.015
protein modification by small protein conjugation or removal GO:0070647 207 0.015
response to light stimulus GO:0009416 135 0.015
myotube differentiation GO:0014902 105 0.015
gtp catabolic process GO:0006184 143 0.015
g protein coupled receptor internalization GO:0002031 3 0.015
circulatory system process GO:0003013 197 0.015
histone modification GO:0016570 159 0.015
vesicle organization GO:0016050 60 0.015
peptide hormone secretion GO:0030072 109 0.015
plasma membrane organization GO:0007009 90 0.015
placenta development GO:0001890 140 0.015
learning GO:0007612 98 0.015
synaptic transmission GO:0007268 329 0.015
negative regulation of organelle organization GO:0010639 90 0.015
protein lipidation GO:0006497 28 0.015
nadph regeneration GO:0006740 2 0.014
protein targeting GO:0006605 143 0.014
positive regulation of protein modification process GO:0031401 299 0.014
sodium ion transport GO:0006814 73 0.014
heart morphogenesis GO:0003007 178 0.014
notch signaling pathway GO:0007219 71 0.014
lateral line system development GO:0048925 1 0.014
organelle localization GO:0051640 179 0.014
nucleoside monophosphate metabolic process GO:0009123 85 0.014
organic hydroxy compound biosynthetic process GO:1901617 77 0.014
glycoprotein biosynthetic process GO:0009101 89 0.014
regulation of hydrolase activity GO:0051336 246 0.014
Human
cellular response to dna damage stimulus GO:0006974 207 0.014
carbon catabolite activation of transcription GO:0045991 4 0.014
intracellular distribution of mitochondria GO:0048312 1 0.014
mitochondrion distribution GO:0048311 4 0.014
response to peptide hormone GO:0043434 127 0.014
macromolecule glycosylation GO:0043413 55 0.014
regulation of gtp catabolic process GO:0033124 113 0.014
regulation of protein complex assembly GO:0043254 83 0.014
regulation of protein transport GO:0051223 163 0.014
negative regulation of cell development GO:0010721 169 0.013
inflammatory response GO:0006954 244 0.013
negative regulation of phosphorylation GO:0042326 166 0.013
regulation of histone modification GO:0031056 56 0.013
cell division GO:0051301 120 0.013
skin development GO:0043588 220 0.013
ovulation cycle GO:0042698 59 0.013
positive regulation of homeostatic process GO:0032846 64 0.013
circadian rhythm GO:0007623 114 0.013
cellular response to lipid GO:0071396 145 0.013
carboxylic acid biosynthetic process GO:0046394 86 0.013
reactive oxygen species metabolic process GO:0072593 84 0.013
epithelial cell development GO:0002064 159 0.013
associative learning GO:0008306 61 0.013
regulation of cellular component biogenesis GO:0044087 181 0.013
neuron death GO:0070997 154 0.013
negative regulation of mapk cascade GO:0043409 65 0.013
actin filament based movement GO:0030048 23 0.013
regulation of organelle organization GO:0033043 289 0.013
pallium development GO:0021543 120 0.013
protein glycosylation GO:0006486 55 0.013
regulation of intracellular transport GO:0032386 159 0.013
cellular response to salt stress GO:0071472 1 0.013
cytosolic calcium ion homeostasis GO:0051480 70 0.013
microtubule based process GO:0007017 236 0.013
detection of stimulus GO:0051606 84 0.013
organophosphate biosynthetic process GO:0090407 122 0.013
dna metabolic process GO:0006259 303 0.013
positive regulation of kinase activity GO:0033674 155 0.013
action potential GO:0001508 78 0.013
regulation of cell projection organization GO:0031344 206 0.013
regulation of neuron apoptotic process GO:0043523 122 0.013
homeostasis of number of cells GO:0048872 210 0.013
regulation of vesicle mediated transport GO:0060627 139 0.013
positive regulation of reverse cholesterol transport GO:1903064 1 0.013
negative regulation of defense response GO:0031348 77 0.012
glycerophospholipid metabolic process GO:0006650 71 0.012
embryonic skeletal system morphogenesis GO:0048704 91 0.012
apoptotic signaling pathway GO:0097190 306 0.012
sensory perception of light stimulus GO:0050953 54 0.012
platelet derived growth factor receptor alpha signaling pathway GO:0035790 3 0.012
nuclear division GO:0000280 158 0.012
neuron apoptotic process GO:0051402 142 0.012
stem cell proliferation GO:0072089 117 0.012
ribonucleoside metabolic process GO:0009119 245 0.012
regulation of vacuole organization GO:0044088 4 0.012
regulation of mitotic cell cycle phase transition GO:1901990 73 0.012
defense response to bacterium GO:0042742 119 0.012
skeletal system morphogenesis GO:0048705 203 0.012
stem cell differentiation GO:0048863 268 0.012
regulation of binding GO:0051098 111 0.012
spermatid differentiation GO:0048515 115 0.012
digestive system development GO:0055123 200 0.012
negative regulation of cytokine production GO:0001818 84 0.012
negative regulation of cellular protein metabolic process GO:0032269 247 0.012
lipid biosynthetic process GO:0008610 179 0.012
palate development GO:0060021 76 0.012
wound healing GO:0042060 157 0.012
atp catabolic process GO:0006200 55 0.012
extracellular matrix organization GO:0030198 147 0.012
lipid localization GO:0010876 126 0.012
establishment of organelle localization GO:0051656 122 0.012
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.012
germ cell development GO:0007281 185 0.012
protein localization to vacuole GO:0072665 4 0.012
response to radiation GO:0009314 165 0.012
cellular response to hormone stimulus GO:0032870 150 0.012
protein maturation GO:0051604 176 0.012
lymphocyte proliferation GO:0046651 164 0.012
cellular response to abiotic stimulus GO:0071214 56 0.012
positive regulation of nucleotide catabolic process GO:0030813 88 0.012
positive regulation of cellular catabolic process GO:0031331 148 0.012
brain segmentation GO:0035284 3 0.012
bone remodeling GO:0046849 53 0.012
regulation of adaptive immune response GO:0002819 90 0.012
regulation of cell cycle process GO:0010564 160 0.012
limb morphogenesis GO:0035108 149 0.012
limb development GO:0060173 166 0.011
negative regulation of cell proliferation GO:0008285 296 0.011
protein ubiquitination GO:0016567 171 0.011
cerebral cortex development GO:0021987 86 0.011
regulation of cell cycle GO:0051726 281 0.011
protein localization to organelle GO:0033365 185 0.011
blood circulation GO:0008015 195 0.011
organelle membrane fusion GO:0090174 1 0.011
myeloid cell differentiation GO:0030099 233 0.011
positive regulation of cell death GO:0010942 224 0.011
regulation of proteolysis GO:0030162 164 0.011
tube formation GO:0035148 140 0.011
positive regulation of engulfment of apoptotic cell GO:1901076 1 0.011
organelle assembly GO:0070925 177 0.011
adult behavior GO:0030534 135 0.011
establishment of protein localization to vacuole GO:0072666 4 0.011
toxin transport GO:1901998 38 0.011
oocyte axis specification GO:0007309 2 0.011
wnt signaling pathway GO:0016055 188 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.011
phagolysosome assembly GO:0001845 3 0.011
regulation of neuron death GO:1901214 134 0.011
blastocyst development GO:0001824 80 0.011
negative regulation of cell activation GO:0050866 111 0.011
axonogenesis GO:0007409 274 0.011
cerebellar granule cell precursor tangential migration GO:0021935 1 0.011
regulation of cellular amino acid metabolic process GO:0006521 5 0.011
mitotic cell cycle process GO:1903047 159 0.011
regulation of gamma aminobutyric acid secretion GO:0014052 2 0.011
regulation of peptide transport GO:0090087 91 0.011
positive regulation of apoptotic process GO:0043065 217 0.011
negative regulation of cell cycle GO:0045786 123 0.011
organic hydroxy compound transport GO:0015850 93 0.010
regulation of organ morphogenesis GO:2000027 144 0.010
interleukin 8 production GO:0032637 4 0.010
rab protein signal transduction GO:0032482 1 0.010
positive regulation of mapk cascade GO:0043410 170 0.010
positive regulation of protein kinase activity GO:0045860 144 0.010
extrinsic apoptotic signaling pathway GO:0097191 126 0.010
compound eye development GO:0048749 1 0.010
muscle contraction GO:0006936 101 0.010
regulation of cellular ketone metabolic process GO:0010565 66 0.010
lateral inhibition GO:0046331 1 0.010
cellular response to organonitrogen compound GO:0071417 145 0.010
positive regulation of protein phosphorylation GO:0001934 242 0.010
endodermal cell fate specification GO:0001714 4 0.010
negative regulation of neuron differentiation GO:0045665 101 0.010
intracellular receptor signaling pathway GO:0030522 74 0.010
regulation of reactive oxygen species metabolic process GO:2000377 40 0.010
embryonic limb morphogenesis GO:0030326 126 0.010
multi multicellular organism process GO:0044706 109 0.010
cell maturation GO:0048469 127 0.010
guanosine containing compound metabolic process GO:1901068 144 0.010
positive regulation of gtp catabolic process GO:0033126 85 0.010
regulation of anatomical structure size GO:0090066 178 0.010
segmentation GO:0035282 93 0.010
protein targeting to vacuole GO:0006623 3 0.010
muscle cell development GO:0055001 133 0.010
ovarian follicle development GO:0001541 40 0.010
reactive oxygen species biosynthetic process GO:1903409 8 0.010
t cell proliferation GO:0042098 120 0.010

Wdr81 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.139
inherited metabolic disorder DOID:655 0 0.084
central nervous system disease DOID:331 0 0.055
disease of anatomical entity DOID:7 0 0.055
nervous system disease DOID:863 0 0.055
immune system disease DOID:2914 0 0.013
hematopoietic system disease DOID:74 0 0.013
neurodegenerative disease DOID:1289 0 0.013
musculoskeletal system disease DOID:17 0 0.012
lysosomal storage disease DOID:3211 0 0.011
connective tissue disease DOID:65 0 0.011
sensory system disease DOID:0050155 0 0.011