Mus musculus

0 known processes

Mmp12

matrix metallopeptidase 12

(Aliases: Mmel,AV378681)

Mmp12 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of eosinophil migration GO:2000418 2 0.844
cell chemotaxis GO:0060326 81 0.815
Zebrafish Mouse
positive regulation of thymocyte migration GO:2000412 2 0.809
eosinophil migration GO:0072677 3 0.808
regulation of b cell chemotaxis GO:2000537 2 0.807
positive regulation of natural killer cell chemotaxis GO:2000503 1 0.805
t helper 2 cell cytokine production GO:0035745 4 0.803
positive regulation of monocyte chemotaxis GO:0090026 2 0.784
positive regulation of cytokine secretion GO:0050715 41 0.778
regulation of thymocyte migration GO:2000410 2 0.756
thymocyte migration GO:0072679 2 0.725
regulation of eosinophil migration GO:2000416 2 0.721
regulation of monocyte chemotaxis GO:0090025 3 0.720
dendritic cell dendrite assembly GO:0097026 2 0.696
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.650
positive regulation of dendritic cell dendrite assembly GO:2000549 1 0.643
positive regulation of defense response GO:0031349 124 0.642
Mouse
mature dendritic cell differentiation GO:0097029 3 0.621
interleukin 12 secretion GO:0072610 3 0.613
positive regulation of t helper 1 cell differentiation GO:0045627 4 0.596
positive regulation of cd4 positive alpha beta t cell proliferation GO:2000563 1 0.594
innate immune response GO:0045087 157 0.584
Mouse
natural killer cell chemotaxis GO:0035747 1 0.564
regulation of inflammatory response GO:0050727 147 0.542
regulation of dendritic cell dendrite assembly GO:2000547 2 0.531
positive regulation of t helper 2 cell cytokine production GO:2000553 3 0.527
positive regulation of cytokine production GO:0001819 174 0.524
positive regulation of secretion GO:0051047 130 0.518
protein secretion GO:0009306 111 0.511
positive regulation of secretion by cell GO:1903532 114 0.511
chemotaxis GO:0006935 247 0.507
Zebrafish Mouse
positive regulation of b cell chemotaxis GO:2000538 2 0.476
granulocyte migration GO:0097530 43 0.476
negative regulation of macrophage apoptotic process GO:2000110 3 0.470
positive regulation of leukocyte mediated immunity GO:0002705 70 0.469
response to molecule of bacterial origin GO:0002237 143 0.466
cdc42 protein signal transduction GO:0032488 0 0.451
regulation of natural killer cell chemotaxis GO:2000501 1 0.447
regulation of t helper 2 cell cytokine production GO:2000551 3 0.446
positive regulation of inflammatory response GO:0050729 47 0.443
regulation of protein transport GO:0051223 163 0.440
negative regulation of immune system process GO:0002683 209 0.438
Mouse
regulation of secretion by cell GO:1903530 249 0.424
positive regulation of immunoglobulin production in mucosal tissue GO:2000558 1 0.408
regulation of cellular response to stress GO:0080135 159 0.407
Mouse
positive regulation of protein secretion GO:0050714 52 0.406
leukocyte chemotaxis GO:0030595 69 0.402
Zebrafish Mouse
cytokine production GO:0001816 319 0.396
positive regulation of type 2 immune response GO:0002830 9 0.388
cd4 positive alpha beta t cell proliferation GO:0035739 2 0.386
t cell activation GO:0042110 289 0.382
immunoglobulin production in mucosal tissue GO:0002426 3 0.381
regulation of immunoglobulin production in mucosal tissue GO:2000557 1 0.380
b cell chemotaxis GO:0035754 3 0.373
cytokine secretion GO:0050663 72 0.368
t helper 1 cell cytokine production GO:0035744 1 0.368
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.366
regulation of cd4 positive alpha beta t cell proliferation GO:2000561 2 0.364
defense response to other organism GO:0098542 197 0.362
Mouse
regulation of b cell mediated immunity GO:0002712 37 0.359
regulation of protein secretion GO:0050708 82 0.353
positive regulation of t helper 1 cell cytokine production GO:2000556 1 0.348
regulation of secretion GO:0051046 274 0.338
positive regulation of immune effector process GO:0002699 107 0.326
regulation of lymphocyte proliferation GO:0050670 117 0.323
leukocyte migration GO:0050900 124 0.321
Zebrafish Mouse
inflammatory response GO:0006954 244 0.317
defense response to bacterium GO:0042742 119 0.317
Mouse
adaptive immune response GO:0002250 155 0.313
cellular ion homeostasis GO:0006873 165 0.304
astrocyte cell migration GO:0043615 3 0.304
organ or tissue specific immune response GO:0002251 13 0.301
alpha beta t cell activation GO:0046631 91 0.300
regulation of cytokine production GO:0001817 266 0.299
cation transport GO:0006812 399 0.294
detection of yeast GO:0001879 2 0.294
regulation of leukocyte mediated immunity GO:0002703 104 0.291
regulation of cell activation GO:0050865 289 0.288
neutrophil chemotaxis GO:0030593 36 0.276
regulation of t cell mediated immunity GO:0002709 34 0.275
positive regulation of leukocyte differentiation GO:1902107 86 0.274
sequestering of calcium ion GO:0051208 18 0.273
cytosolic calcium ion homeostasis GO:0051480 70 0.272
cation homeostasis GO:0055080 212 0.269
mature natural killer cell chemotaxis GO:0035782 1 0.269
regulation of vesicle mediated transport GO:0060627 139 0.259
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.254
leukocyte mediated immunity GO:0002443 174 0.253
negative regulation of homeostatic process GO:0032845 71 0.249
regulation of lymphocyte activation GO:0051249 240 0.243
positive regulation of neutrophil chemotaxis GO:0090023 12 0.234
regulation of cd4 positive alpha beta t cell activation GO:2000514 24 0.233
activation of mapk activity GO:0000187 59 0.232
regulation of cytokine secretion GO:0050707 61 0.231
sequestering of metal ion GO:0051238 19 0.230
regulation of t cell activation GO:0050863 170 0.227
regulation of cell migration GO:0030334 219 0.218
Mouse
myeloid cell apoptotic process GO:0033028 22 0.215
regulation of response to wounding GO:1903034 189 0.212
regulation of defense response GO:0031347 233 0.212
Mouse
t cell mediated immunity GO:0002456 50 0.210
regulation of protein localization GO:0032880 231 0.205
calcium ion transport into cytosol GO:0060402 48 0.203
leukocyte differentiation GO:0002521 342 0.201
metal ion homeostasis GO:0055065 189 0.198
positive regulation of t cell differentiation GO:0045582 52 0.198
regulation of ion homeostasis GO:2000021 64 0.197
regulation of adaptive immune response GO:0002819 90 0.196
rho protein signal transduction GO:0007266 32 0.193
cytosolic calcium ion transport GO:0060401 48 0.189
release of sequestered calcium ion into cytosol GO:0051209 42 0.188
regulation of cell motility GO:2000145 236 0.188
Mouse
regulation of map kinase activity GO:0043405 120 0.188
regulation of homeostatic process GO:0032844 182 0.186
neutrophil migration GO:1990266 37 0.186
cellular response to lipopolysaccharide GO:0071222 77 0.186
leukocyte proliferation GO:0070661 172 0.185
positive regulation of programmed cell death GO:0043068 218 0.182
Mouse
antigen processing and presentation GO:0019882 47 0.180
cellular homeostasis GO:0019725 240 0.180
immunoglobulin mediated immune response GO:0016064 69 0.180
positive regulation of leukocyte proliferation GO:0070665 73 0.174
regulation of leukocyte proliferation GO:0070663 121 0.173
regulation of t cell proliferation GO:0042129 92 0.172
response to lipopolysaccharide GO:0032496 128 0.171
regulation of myoblast differentiation GO:0045661 29 0.170
regulation of establishment of protein localization GO:0070201 181 0.170
positive regulation of cell motility GO:2000147 116 0.169
cellular calcium ion homeostasis GO:0006874 119 0.169
myeloid cell differentiation GO:0030099 233 0.169
regulation of neutrophil chemotaxis GO:0090022 14 0.168
regulation of protein serine threonine kinase activity GO:0071900 157 0.168
cytokine production involved in immune response GO:0002367 34 0.167
positive regulation of response to wounding GO:1903036 66 0.167
immune effector process GO:0002252 321 0.166
t helper 1 cell differentiation GO:0045063 13 0.163
positive regulation of cell migration GO:0030335 109 0.160
positive regulation of tumor necrosis factor production GO:0032760 30 0.158
positive regulation of homeostatic process GO:0032846 64 0.158
response to interleukin 4 GO:0070670 23 0.154
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.153
positive regulation of protein transport GO:0051222 93 0.152
jnk cascade GO:0007254 72 0.152
regulation of lymphocyte mediated immunity GO:0002706 84 0.151
granulocyte chemotaxis GO:0071621 39 0.150
positive regulation of neuron apoptotic process GO:0043525 25 0.150
regulation of antigen processing and presentation GO:0002577 10 0.146
cellular metal ion homeostasis GO:0006875 151 0.146
cellular response to cytokine stimulus GO:0071345 189 0.145
positive regulation of cell activation GO:0050867 158 0.142
detection of fungus GO:0016046 2 0.141
negative regulation of myoblast differentiation GO:0045662 18 0.140
antibacterial peptide secretion GO:0002779 1 0.140
Mouse
blood vessel morphogenesis GO:0048514 285 0.139
t cell proliferation GO:0042098 120 0.138
lymphocyte proliferation GO:0046651 164 0.137
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.137
t helper cell differentiation GO:0042093 28 0.137
regulation of ion transport GO:0043269 215 0.136
regulation of tumor necrosis factor production GO:0032680 49 0.136
tumor necrosis factor production GO:0032640 50 0.135
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.131
muscle cell differentiation GO:0042692 261 0.131
dendritic cell chemotaxis GO:0002407 7 0.131
positive regulation of lymphocyte activation GO:0051251 140 0.131
positive regulation of granulocyte chemotaxis GO:0071624 12 0.129
regulation of mapk cascade GO:0043408 248 0.129
negative regulation of intracellular signal transduction GO:1902532 167 0.127
Mouse
positive regulation of neutrophil mediated killing of symbiont cell GO:0070961 1 0.127
cellular response to molecule of bacterial origin GO:0071219 83 0.127
maintenance of location GO:0051235 89 0.124
positive regulation of cellular catabolic process GO:0031331 148 0.123
angiogenesis GO:0001525 201 0.123
alpha beta t cell activation involved in immune response GO:0002287 31 0.122
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.120
regulation of cytokine biosynthetic process GO:0042035 59 0.120
cellular response to interleukin 4 GO:0071353 21 0.117
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.117
calcium ion homeostasis GO:0055074 127 0.116
positive regulation of b cell mediated immunity GO:0002714 26 0.115
cellular ketone metabolic process GO:0042180 84 0.114
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.114
purine ribonucleotide metabolic process GO:0009150 290 0.113
cellular response to biotic stimulus GO:0071216 92 0.113
positive regulation of nucleotide metabolic process GO:0045981 114 0.112
regulation of cell projection assembly GO:0060491 38 0.112
endocytosis GO:0006897 168 0.111
regulation of transferase activity GO:0051338 263 0.111
positive regulation of lymphocyte proliferation GO:0050671 70 0.109
cell activation involved in immune response GO:0002263 126 0.109
positive regulation of innate immune response GO:0045089 80 0.109
Mouse
positive regulation of phagocytosis GO:0050766 26 0.109
skeletal muscle fiber development GO:0048741 58 0.108
mapk cascade GO:0000165 281 0.107
myeloid leukocyte migration GO:0097529 57 0.107
Zebrafish Mouse
divalent metal ion transport GO:0070838 172 0.106
regulation of vasculature development GO:1901342 88 0.106
response to transforming growth factor beta GO:0071559 88 0.105
positive regulation of protein modification process GO:0031401 299 0.104
positive regulation of kinase activity GO:0033674 155 0.103
myotube differentiation GO:0014902 105 0.103
regulation of t cell differentiation GO:0045580 83 0.103
leukocyte activation involved in immune response GO:0002366 126 0.102
regulation of skeletal muscle fiber development GO:0048742 36 0.102
positive regulation of cytokine production involved in immune response GO:0002720 19 0.101
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.101
amine metabolic process GO:0009308 45 0.101
myeloid leukocyte differentiation GO:0002573 119 0.100
lipid transport GO:0006869 98 0.100
positive regulation of cd4 positive alpha beta t cell differentiation GO:0043372 14 0.098
positive regulation of cell projection organization GO:0031346 95 0.098
positive regulation of endocytosis GO:0045807 42 0.098
divalent inorganic cation homeostasis GO:0072507 138 0.098
muscle tissue development GO:0060537 308 0.097
positive regulation of neutrophil mediated cytotoxicity GO:0070960 1 0.096
dendritic cell differentiation GO:0097028 26 0.096
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.096
nucleobase containing small molecule metabolic process GO:0055086 352 0.096
regulation of t helper 1 cell differentiation GO:0045625 7 0.096
positive regulation of hydrolase activity GO:0051345 148 0.095
defense response to gram positive bacterium GO:0050830 50 0.093
Mouse
nucleoside phosphate catabolic process GO:1901292 222 0.093
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.093
regulation of stress activated mapk cascade GO:0032872 69 0.092
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.091
regulation of myotube differentiation GO:0010830 62 0.090
ribose phosphate metabolic process GO:0019693 291 0.090
muscle fiber development GO:0048747 76 0.090
b cell mediated immunity GO:0019724 71 0.089
cell surface pattern recognition receptor signaling pathway GO:0002752 2 0.089
myotube cell development GO:0014904 60 0.089
regulation of protein kinase activity GO:0045859 232 0.089
small gtpase mediated signal transduction GO:0007264 97 0.089
positive regulation of interleukin 1 secretion GO:0050716 14 0.089
activation of jun kinase activity GO:0007257 15 0.087
carbohydrate derivative catabolic process GO:1901136 231 0.087
positive regulation of alpha beta t cell differentiation GO:0046638 28 0.087
multicellular organismal homeostasis GO:0048871 164 0.086
regulation of membrane potential GO:0042391 192 0.086
positive regulation of apoptotic process GO:0043065 217 0.086
Mouse
cellular chemical homeostasis GO:0055082 215 0.086
positive regulation of protein phosphorylation GO:0001934 242 0.086
reactive oxygen species metabolic process GO:0072593 84 0.085
regulation of epithelial cell proliferation GO:0050678 141 0.084
Rat
gland development GO:0048732 330 0.084
regulation of kinase activity GO:0043549 249 0.084
positive regulation of lymphocyte differentiation GO:0045621 61 0.084
nucleoside phosphate metabolic process GO:0006753 338 0.083
nitrogen compound transport GO:0071705 271 0.083
Mouse
regulation of lymphocyte differentiation GO:0045619 107 0.083
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.082
regulation of cellular component biogenesis GO:0044087 181 0.081
regulation of reactive oxygen species metabolic process GO:2000377 40 0.081
stress activated protein kinase signaling cascade GO:0031098 81 0.081
lymphocyte mediated immunity GO:0002449 139 0.081
regulation of ras gtpase activity GO:0032318 88 0.080
positive regulation of angiogenesis GO:0045766 46 0.079
regulation of hormone levels GO:0010817 211 0.079
regulation of neutrophil mediated killing of gram negative bacterium GO:0070951 1 0.079
interleukin 1 production GO:0032612 31 0.079
organic anion transport GO:0015711 137 0.078
leukocyte apoptotic process GO:0071887 71 0.078
response to organonitrogen compound GO:0010243 246 0.078
Mouse
lymphocyte differentiation GO:0030098 242 0.077
regulation of jnk cascade GO:0046328 62 0.077
regulation of alpha beta t cell activation GO:0046634 53 0.077
purine nucleotide metabolic process GO:0006163 302 0.076
nucleoside metabolic process GO:0009116 246 0.075
positive regulation of syncytium formation by plasma membrane fusion GO:0060143 17 0.075
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.075
organic hydroxy compound transport GO:0015850 93 0.075
activation of innate immune response GO:0002218 56 0.075
regulation of alpha beta t cell differentiation GO:0046637 35 0.075
striated muscle cell development GO:0055002 125 0.074
regulation of cd4 positive alpha beta t cell differentiation GO:0043370 21 0.074
response to molecule of fungal origin GO:0002238 4 0.074
protein kinase b signaling GO:0043491 74 0.074
Mouse
peptide secretion GO:0002790 114 0.073
Mouse
production of molecular mediator of immune response GO:0002440 103 0.073
Mouse
regulation of alpha beta t cell proliferation GO:0046640 18 0.072
i kappab kinase nf kappab signaling GO:0007249 85 0.072
regulation of rho protein signal transduction GO:0035023 71 0.072
regulation of muscle tissue development GO:1901861 97 0.072
response to drug GO:0042493 75 0.071
Mouse Rat
negative regulation of muscle cell differentiation GO:0051148 33 0.071
cytokine biosynthetic process GO:0042089 68 0.071
organic cyclic compound catabolic process GO:1901361 295 0.071
regulation of lymphocyte migration GO:2000401 14 0.070
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.070
ribonucleoside triphosphate catabolic process GO:0009203 199 0.070
ribonucleotide catabolic process GO:0009261 208 0.070
regulation of t helper cell differentiation GO:0045622 14 0.070
positive regulation of t helper 1 type immune response GO:0002827 12 0.069
t helper 1 type immune response GO:0042088 25 0.069
stress activated mapk cascade GO:0051403 80 0.069
macrophage chemotaxis GO:0048246 14 0.069
Zebrafish Mouse
regulation of endocytosis GO:0030100 69 0.069
pattern recognition receptor signaling pathway GO:0002221 47 0.069
cellular divalent inorganic cation homeostasis GO:0072503 127 0.068
positive regulation of t cell cytokine production GO:0002726 5 0.068
peptide transport GO:0015833 133 0.068
Mouse
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.068
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.067
gliogenesis GO:0042063 141 0.067
response to organic cyclic compound GO:0014070 198 0.067
Rat
purine ribonucleoside metabolic process GO:0046128 241 0.066
lipid biosynthetic process GO:0008610 179 0.066
activation of immune response GO:0002253 138 0.066
ribonucleoside metabolic process GO:0009119 245 0.066
regulation of t helper 1 type immune response GO:0002825 17 0.065
regulation of striated muscle cell differentiation GO:0051153 81 0.065
calcium ion transport GO:0006816 159 0.065
regulation of leukocyte differentiation GO:1902105 159 0.065
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.065
cytokine metabolic process GO:0042107 71 0.065
regulation of type 2 immune response GO:0002828 18 0.063
membrane organization GO:0061024 245 0.063
positive regulation of map kinase activity GO:0043406 84 0.063
positive regulation of neuron death GO:1901216 28 0.063
regulation of glycoprotein biosynthetic process GO:0010559 12 0.063
immune response regulating signaling pathway GO:0002764 125 0.062
regulation of cytokine production involved in immune response GO:0002718 26 0.062
positive regulation of cytokine biosynthetic process GO:0042108 40 0.061
purine nucleotide catabolic process GO:0006195 211 0.060
regulation of cellular amino acid metabolic process GO:0006521 5 0.060
positive regulation of protein kinase activity GO:0045860 144 0.060
positive regulation of glycoprotein metabolic process GO:1903020 6 0.060
alpha beta t cell differentiation GO:0046632 69 0.059
regulation of chemokine production GO:0032642 30 0.059
reactive nitrogen species metabolic process GO:2001057 0 0.059
cellular amine metabolic process GO:0044106 44 0.059
positive regulation of neutrophil migration GO:1902624 12 0.059
positive regulation of mapk cascade GO:0043410 170 0.059
response to extracellular stimulus GO:0009991 127 0.059
nucleoside triphosphate catabolic process GO:0009143 205 0.058
ras protein signal transduction GO:0007265 77 0.058
positive regulation of t cell mediated immunity GO:0002711 24 0.058
interleukin 1 beta production GO:0032611 30 0.058
ribonucleotide metabolic process GO:0009259 291 0.058
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.058
regulation of hydrolase activity GO:0051336 246 0.057
regulation of protein kinase b signaling GO:0051896 56 0.057
Mouse
purine nucleoside metabolic process GO:0042278 241 0.057
regulation of cell adhesion GO:0030155 154 0.057
immune response activating signal transduction GO:0002757 116 0.056
organic acid transport GO:0015849 101 0.056
immunoglobulin production GO:0002377 73 0.056
cell recognition GO:0008037 83 0.056
nucleotide metabolic process GO:0009117 332 0.056
purine containing compound metabolic process GO:0072521 311 0.056
myeloid cell activation involved in immune response GO:0002275 34 0.055
regulation of innate immune response GO:0045088 91 0.055
Mouse
receptor mediated endocytosis GO:0006898 51 0.055
purine nucleoside triphosphate catabolic process GO:0009146 203 0.055
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.055
positive regulation of transferase activity GO:0051347 167 0.055
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.055
purine nucleoside triphosphate metabolic process GO:0009144 226 0.055
lipid localization GO:0010876 126 0.055
regulation of defense response to bacterium GO:1900424 3 0.054
cell cell recognition GO:0009988 44 0.054
cd4 positive alpha beta t cell activation GO:0035710 45 0.054
lymphocyte chemotaxis GO:0048247 10 0.054
positive regulation of t cell proliferation GO:0042102 52 0.054
mucosal immune response GO:0002385 13 0.054
regulation of immunoglobulin mediated immune response GO:0002889 37 0.053
glycosyl compound catabolic process GO:1901658 206 0.053
apoptotic signaling pathway GO:0097190 306 0.053
regulation of intracellular transport GO:0032386 159 0.053
axonogenesis GO:0007409 274 0.053
nucleotide catabolic process GO:0009166 217 0.052
heterocycle catabolic process GO:0046700 280 0.052
antibacterial humoral response GO:0019731 8 0.052
Mouse
divalent inorganic cation transport GO:0072511 178 0.052
positive regulation of gtp catabolic process GO:0033126 85 0.051
positive regulation of interleukin 12 production GO:0032735 21 0.051
regulation of ras protein signal transduction GO:0046578 114 0.051
carbohydrate derivative biosynthetic process GO:1901137 183 0.051
cell adhesion GO:0007155 329 0.051
anatomical structure homeostasis GO:0060249 145 0.051
inflammatory response to wounding GO:0090594 4 0.051
gtp metabolic process GO:0046039 144 0.051
regulation of granulocyte chemotaxis GO:0071622 17 0.051
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.050
positive regulation of lymphocyte migration GO:2000403 11 0.050
eosinophil degranulation GO:0043308 1 0.050
positive regulation of adaptive immune response GO:0002821 61 0.050
positive regulation of immunoglobulin mediated immune response GO:0002891 26 0.050
positive regulation of receptor mediated endocytosis GO:0048260 9 0.050
regulation of chemotaxis GO:0050920 53 0.050
Mouse
neutrophil mediated killing of gram positive bacterium GO:0070946 2 0.050
regulation of angiogenesis GO:0045765 81 0.050
myeloid leukocyte activation GO:0002274 83 0.050
aromatic compound catabolic process GO:0019439 286 0.049
positive regulation of cell death GO:0010942 224 0.049
Mouse
positive regulation of cd4 positive alpha beta t cell activation GO:2000516 16 0.049
glycoprotein biosynthetic process GO:0009101 89 0.049
positive regulation of jnk cascade GO:0046330 46 0.049
myoblast differentiation GO:0045445 52 0.049
reactive oxygen species biosynthetic process GO:1903409 8 0.049
regulation of leukocyte apoptotic process GO:2000106 56 0.049
positive regulation of alpha beta t cell activation GO:0046635 39 0.048
regulation of syncytium formation by plasma membrane fusion GO:0060142 23 0.048
positive regulation of jun kinase activity GO:0043507 30 0.048
positive regulation of stress activated mapk cascade GO:0032874 48 0.048
purine containing compound catabolic process GO:0072523 213 0.048
interleukin 12 production GO:0032615 32 0.048
regulation of cellular ketone metabolic process GO:0010565 66 0.047
developmental growth involved in morphogenesis GO:0060560 138 0.047
Mouse
positive regulation of t cell activation GO:0050870 101 0.047
stimulatory c type lectin receptor signaling pathway GO:0002223 2 0.047
muscle cell development GO:0055001 133 0.047
lymphocyte activation involved in immune response GO:0002285 93 0.047
cellular response to organonitrogen compound GO:0071417 145 0.046
Mouse
regulation of interleukin 1 beta secretion GO:0050706 15 0.046
regulation of organelle organization GO:0033043 289 0.046
response to radiation GO:0009314 165 0.046
positive regulation of alpha beta t cell proliferation GO:0046641 12 0.046
protein catabolic process GO:0030163 221 0.046
Mouse
regulation of cellular catabolic process GO:0031329 242 0.046
organic hydroxy compound metabolic process GO:1901615 203 0.046
positive regulation of calcium ion transport GO:0051928 27 0.046
positive regulation of gtpase activity GO:0043547 85 0.046
cellular nitrogen compound catabolic process GO:0044270 280 0.045
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.045
epithelial cell proliferation GO:0050673 174 0.045
Rat
cellular response to lipid GO:0071396 145 0.045
ribonucleoside triphosphate metabolic process GO:0009199 220 0.045
striated muscle tissue development GO:0014706 293 0.045
anion transport GO:0006820 177 0.045
purine ribonucleoside catabolic process GO:0046130 205 0.045
neutrophil mediated killing of gram negative bacterium GO:0070945 4 0.045
regulation of immunoglobulin production GO:0002637 42 0.044
regulation of nucleotide catabolic process GO:0030811 122 0.044
organonitrogen compound catabolic process GO:1901565 264 0.044
purine ribonucleotide catabolic process GO:0009154 208 0.044
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.044
g protein coupled receptor signaling pathway GO:0007186 243 0.044
positive regulation of cellular amine metabolic process GO:0033240 5 0.043
positive regulation of intracellular transport GO:0032388 70 0.043
neutrophil mediated immunity GO:0002446 19 0.043
positive regulation of muscle cell differentiation GO:0051149 39 0.043
regulation of adiponectin secretion GO:0070163 2 0.043
branching involved in mammary gland duct morphogenesis GO:0060444 27 0.043
t cell differentiation involved in immune response GO:0002292 30 0.043
t cell extravasation GO:0072683 4 0.043
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.042
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.042
syncytium formation by plasma membrane fusion GO:0000768 42 0.042
regulation of interleukin 1 secretion GO:0050704 15 0.041
phagocytosis GO:0006909 66 0.041
nucleoside triphosphate metabolic process GO:0009141 230 0.041
regulation of cellular amine metabolic process GO:0033238 20 0.041
cellular response to growth factor stimulus GO:0071363 197 0.041
neuron death GO:0070997 154 0.041
second messenger mediated signaling GO:0019932 73 0.041
regulated secretory pathway GO:0045055 32 0.041
nucleoside catabolic process GO:0009164 206 0.040
regulation of cell projection organization GO:0031344 206 0.040
inflammatory cell apoptotic process GO:0006925 11 0.040
lymphocyte migration GO:0072676 26 0.040
tissue homeostasis GO:0001894 115 0.040
positive regulation of cellular component biogenesis GO:0044089 94 0.040
homeostasis of number of cells GO:0048872 210 0.040
interleukin 1 secretion GO:0050701 16 0.039
regulation of neuron apoptotic process GO:0043523 122 0.039
hormone secretion GO:0046879 128 0.039
regulation of production of molecular mediator of immune response GO:0002700 65 0.039
cellular response to peptidoglycan GO:0071224 4 0.039
positive regulation of rho gtpase activity GO:0032321 41 0.038
regulation of neutrophil migration GO:1902622 14 0.038
regulation of jun kinase activity GO:0043506 40 0.038
regulation of purine nucleotide catabolic process GO:0033121 122 0.038
neutrophil mediated killing of bacterium GO:0070944 6 0.038
alpha beta t cell proliferation GO:0046633 21 0.038
positive regulation of antigen processing and presentation GO:0002579 10 0.038
t cell differentiation GO:0030217 174 0.038
interleukin 1 beta secretion GO:0050702 16 0.037
regulation of apoptotic signaling pathway GO:2001233 197 0.037
positive regulation of membrane protein ectodomain proteolysis GO:0051044 3 0.037
alcohol metabolic process GO:0006066 116 0.037
t cell migration GO:0072678 19 0.037
activation of mapk activity involved in innate immune response GO:0035419 2 0.037
immune complex clearance by monocytes and macrophages GO:0002436 2 0.036
t cell activation involved in immune response GO:0002286 43 0.036
interleukin 2 biosynthetic process GO:0042094 15 0.036
cytoplasmic transport GO:0016482 234 0.036
antimicrobial peptide production GO:0002775 2 0.036
Mouse
regulation of nucleotide metabolic process GO:0006140 169 0.035
positive regulation of myoblast differentiation GO:0045663 8 0.035
positive regulation of t cell costimulation GO:2000525 2 0.035
regulation of phagocytosis GO:0050764 33 0.035
cellular lipid metabolic process GO:0044255 323 0.035
negative regulation of phosphorylation GO:0042326 166 0.035
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.035
regulation of interferon gamma production GO:0032649 57 0.035
positive regulation of myotube differentiation GO:0010831 24 0.035
interaction with symbiont GO:0051702 14 0.034

Mmp12 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.076