Mus musculus

57 known processes

Mmp13

matrix metallopeptidase 13

(Aliases: MMP-13,Clg,Mmp1)

Mmp13 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of defense response GO:0031349 124 0.440
Mouse
defense response to bacterium GO:0042742 119 0.367
Mouse
positive regulation of programmed cell death GO:0043068 218 0.362
Mouse
positive regulation of neutrophil mediated killing of symbiont cell GO:0070961 1 0.338
positive regulation of neutrophil mediated cytotoxicity GO:0070960 1 0.313
immune effector process GO:0002252 321 0.288
regulation of neutrophil mediated killing of gram negative bacterium GO:0070951 1 0.287
cation transport GO:0006812 399 0.281
regulation of defense response to bacterium GO:1900424 3 0.277
cellular response to lipopolysaccharide GO:0071222 77 0.272
defense response to other organism GO:0098542 197 0.254
Mouse
inflammatory response GO:0006954 244 0.237
defense response to gram positive bacterium GO:0050830 50 0.199
Mouse
positive regulation of cytokine production GO:0001819 174 0.195
response to molecule of bacterial origin GO:0002237 143 0.195
positive regulation of leukocyte mediated immunity GO:0002705 70 0.194
positive regulation of innate immune response GO:0045089 80 0.192
Mouse
neutrophil mediated killing of gram negative bacterium GO:0070945 4 0.185
cell killing GO:0001906 67 0.185
cytokine production GO:0001816 319 0.179
positive regulation of cell death GO:0010942 224 0.177
Mouse
cellular response to molecule of bacterial origin GO:0071219 83 0.175
regulation of defense response GO:0031347 233 0.174
Mouse
cellular response to biotic stimulus GO:0071216 92 0.172
production of molecular mediator of immune response GO:0002440 103 0.171
Mouse
chemotaxis GO:0006935 247 0.170
Mouse
reactive oxygen species metabolic process GO:0072593 84 0.162
regulation of t helper 1 cell cytokine production GO:2000554 1 0.161
cellular homeostasis GO:0019725 240 0.160
lymphocyte proliferation GO:0046651 164 0.143
metal ion homeostasis GO:0055065 189 0.142
organonitrogen compound biosynthetic process GO:1901566 192 0.142
Mouse
leukocyte mediated cytotoxicity GO:0001909 62 0.135
leukocyte mediated immunity GO:0002443 174 0.135
cellular chemical homeostasis GO:0055082 215 0.124
cellular response to lipid GO:0071396 145 0.124
regulation of hydrolase activity GO:0051336 246 0.120
regulation of reactive oxygen species metabolic process GO:2000377 40 0.117
positive regulation of apoptotic process GO:0043065 217 0.116
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.115
regulation of neutrophil mediated killing of symbiont cell GO:0070949 2 0.115
regulation of cellular ketone metabolic process GO:0010565 66 0.115
cation homeostasis GO:0055080 212 0.114
divalent inorganic cation transport GO:0072511 178 0.113
cellular amino acid metabolic process GO:0006520 103 0.113
amine metabolic process GO:0009308 45 0.111
positive regulation of neutrophil mediated killing of fungus GO:0070965 1 0.110
homeostasis of number of cells GO:0048872 210 0.110
positive regulation of natural killer cell chemotaxis GO:2000503 1 0.107
cell chemotaxis GO:0060326 81 0.106
Mouse
regulation of neutrophil mediated killing of fungus GO:0070953 1 0.103
interspecies interaction between organisms GO:0044419 83 0.102
negative regulation of cell proliferation GO:0008285 296 0.102
gland development GO:0048732 330 0.102
leukocyte migration GO:0050900 124 0.101
Mouse
response to organic cyclic compound GO:0014070 198 0.100
Rat
response to lipopolysaccharide GO:0032496 128 0.100
t cell proliferation GO:0042098 120 0.099
negative regulation of cellular protein metabolic process GO:0032269 247 0.099
regulation of neutrophil mediated cytotoxicity GO:0070948 2 0.098
cellular amine metabolic process GO:0044106 44 0.096
myeloid cell differentiation GO:0030099 233 0.096
cellular ion homeostasis GO:0006873 165 0.096
calcium ion homeostasis GO:0055074 127 0.096
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.095
positive regulation of hematopoietic stem cell proliferation GO:1902035 2 0.095
regulation of mapk cascade GO:0043408 248 0.094
calcium ion transport GO:0006816 159 0.094
positive regulation of immune effector process GO:0002699 107 0.094
defense response to virus GO:0051607 68 0.093
innate immune response GO:0045087 157 0.093
Mouse
cellular metal ion homeostasis GO:0006875 151 0.093
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.092
positive regulation of t helper 1 cell differentiation GO:0045627 4 0.091
cellular response to cytokine stimulus GO:0071345 189 0.091
sequestering of calcium ion GO:0051208 18 0.091
regulation of cellular amino acid metabolic process GO:0006521 5 0.090
regulation of inflammatory response GO:0050727 147 0.090
positive regulation of monocyte chemotaxis GO:0090026 2 0.086
response to organonitrogen compound GO:0010243 246 0.086
Mouse
regulation of cell killing GO:0031341 40 0.085
inflammatory response to wounding GO:0090594 4 0.085
regulation of monocyte chemotaxis GO:0090025 3 0.085
nucleobase containing small molecule metabolic process GO:0055086 352 0.084
immune response activating signal transduction GO:0002757 116 0.084
regulation of thymocyte migration GO:2000410 2 0.083
regulation of lymphocyte proliferation GO:0050670 117 0.082
sequestering of metal ion GO:0051238 19 0.082
negative regulation of immune system process GO:0002683 209 0.081
Mouse
defense response to gram negative bacterium GO:0050829 28 0.081
Mouse
organic acid transport GO:0015849 101 0.081
transmembrane transport GO:0055085 412 0.081
regulation of homeostatic process GO:0032844 182 0.080
positive regulation of cellular amine metabolic process GO:0033240 5 0.080
cellular ketone metabolic process GO:0042180 84 0.080
regulation of multi organism process GO:0043900 111 0.079
positive regulation of hydrolase activity GO:0051345 148 0.078
regulation of b cell chemotaxis GO:2000537 2 0.078
leukocyte homeostasis GO:0001776 79 0.078
keratinocyte migration GO:0051546 3 0.077
apoptotic signaling pathway GO:0097190 306 0.077
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.077
regulation of secretion GO:0051046 274 0.076
leukocyte differentiation GO:0002521 342 0.076
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.075
regulation of ion homeostasis GO:2000021 64 0.074
nitrogen compound transport GO:0071705 271 0.074
Mouse
protein catabolic process GO:0030163 221 0.074
Mouse
regulation of leukocyte mediated immunity GO:0002703 104 0.073
dendritic cell dendrite assembly GO:0097026 2 0.072
leukocyte chemotaxis GO:0030595 69 0.072
Mouse
adaptive immune response GO:0002250 155 0.072
positive regulation of eosinophil migration GO:2000418 2 0.072
nucleoside phosphate metabolic process GO:0006753 338 0.071
regulation of hematopoietic stem cell proliferation GO:1902033 3 0.071
negative regulation of protein metabolic process GO:0051248 282 0.070
regulation of t cell activation GO:0050863 170 0.070
negative regulation of phosphate metabolic process GO:0045936 184 0.070
purine ribonucleotide catabolic process GO:0009154 208 0.070
natural killer cell chemotaxis GO:0035747 1 0.070
muscle tissue development GO:0060537 308 0.069
carbohydrate derivative biosynthetic process GO:1901137 183 0.069
thymocyte migration GO:0072679 2 0.069
positive regulation of t helper 2 cell cytokine production GO:2000553 3 0.068
regulation of establishment of protein localization GO:0070201 181 0.067
purine ribonucleotide metabolic process GO:0009150 290 0.067
positive regulation of mapk cascade GO:0043410 170 0.067
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.066
cellular nitrogen compound catabolic process GO:0044270 280 0.066
positive regulation of thymocyte migration GO:2000412 2 0.065
cytokine production involved in immune response GO:0002367 34 0.065
purine nucleotide metabolic process GO:0006163 302 0.065
nucleoside metabolic process GO:0009116 246 0.064
t helper 2 cell cytokine production GO:0035745 4 0.064
regulation of cytokine production GO:0001817 266 0.063
regulation of secretion by cell GO:1903530 249 0.062
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.062
muscle cell differentiation GO:0042692 261 0.061
organonitrogen compound catabolic process GO:1901565 264 0.061
Rat
immune response regulating signaling pathway GO:0002764 125 0.061
regulation of protein serine threonine kinase activity GO:0071900 157 0.061
negative regulation of molecular function GO:0044092 258 0.061
positive regulation of protein phosphorylation GO:0001934 242 0.061
regulation of neutrophil mediated killing of bacterium GO:0070950 1 0.061
anion transport GO:0006820 177 0.061
myeloid leukocyte migration GO:0097529 57 0.060
Mouse
cell type specific apoptotic process GO:0097285 268 0.060
cellular calcium ion homeostasis GO:0006874 119 0.060
disruption by host of symbiont cells GO:0051852 11 0.060
regulation of muscle tissue development GO:1901861 97 0.060
regulation of cellular response to stress GO:0080135 159 0.059
Mouse
heterocycle catabolic process GO:0046700 280 0.059
killing by host of symbiont cells GO:0051873 11 0.058
regulation of defense response to fungus GO:1900150 1 0.058
organic cyclic compound catabolic process GO:1901361 295 0.058
regulation of apoptotic signaling pathway GO:2001233 197 0.058
positive regulation of cd4 positive alpha beta t cell proliferation GO:2000563 1 0.057
regulation of skeletal muscle fiber development GO:0048742 36 0.056
carboxylic acid transport GO:0046942 100 0.056
pattern recognition receptor signaling pathway GO:0002221 47 0.055
positive regulation of cell killing GO:0031343 33 0.055
peptide transport GO:0015833 133 0.055
Mouse
reactive nitrogen species metabolic process GO:2001057 0 0.055
blood vessel morphogenesis GO:0048514 285 0.055
negative regulation of phosphorus metabolic process GO:0010563 184 0.055
antibacterial peptide production GO:0002778 2 0.054
Mouse
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.054
jnk cascade GO:0007254 72 0.054
neutrophil migration GO:1990266 37 0.054
antimicrobial peptide biosynthetic process GO:0002777 2 0.054
Mouse
cytoplasmic transport GO:0016482 234 0.054
regulation of cellular amine metabolic process GO:0033238 20 0.053
mapk cascade GO:0000165 281 0.053
myeloid leukocyte differentiation GO:0002573 119 0.053
leukocyte proliferation GO:0070661 172 0.053
regulation of innate immune response GO:0045088 91 0.053
Mouse
regulation of cell activation GO:0050865 289 0.053
carbohydrate derivative catabolic process GO:1901136 231 0.053
disruption of cells of other organism involved in symbiotic interaction GO:0051818 13 0.053
regulation of t helper 2 cell cytokine production GO:2000551 3 0.052
regulation of t cell proliferation GO:0042129 92 0.052
regulation of cd4 positive alpha beta t cell proliferation GO:2000561 2 0.052
divalent inorganic cation homeostasis GO:0072507 138 0.052
positive regulation of killing of cells of other organism GO:0051712 3 0.051
mature dendritic cell differentiation GO:0097029 3 0.051
striated muscle cell development GO:0055002 125 0.051
glycosyl compound catabolic process GO:1901658 206 0.051
granulocyte chemotaxis GO:0071621 39 0.051
rho protein signal transduction GO:0007266 32 0.051
immunoglobulin production in mucosal tissue GO:0002426 3 0.051
ras protein signal transduction GO:0007265 77 0.051
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.051
positive regulation of cytokine production involved in immune response GO:0002720 19 0.051
ribose phosphate metabolic process GO:0019693 291 0.051
lymphocyte mediated immunity GO:0002449 139 0.051
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.050
nucleotide metabolic process GO:0009117 332 0.050
purine containing compound catabolic process GO:0072523 213 0.050
sensory perception GO:0007600 245 0.050
nucleoside triphosphate metabolic process GO:0009141 230 0.050
negative regulation of phosphorylation GO:0042326 166 0.050
activation of innate immune response GO:0002218 56 0.049
regulation of eosinophil migration GO:2000416 2 0.049
positive regulation of protein modification process GO:0031401 299 0.049
regulation of cellular catabolic process GO:0031329 242 0.049
purine containing compound metabolic process GO:0072521 311 0.048
regulation of response to wounding GO:1903034 189 0.048
ribonucleoside triphosphate metabolic process GO:0009199 220 0.047
organic hydroxy compound metabolic process GO:1901615 203 0.047
developmental maturation GO:0021700 193 0.047
Mouse
reactive oxygen species biosynthetic process GO:1903409 8 0.046
b cell activation GO:0042113 161 0.046
regulation of peptidase activity GO:0052547 96 0.046
interaction with symbiont GO:0051702 14 0.046
regulation of lymphocyte activation GO:0051249 240 0.045
ribonucleoside metabolic process GO:0009119 245 0.045
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.045
regulation of ion transport GO:0043269 215 0.045
striated muscle tissue development GO:0014706 293 0.045
negative regulation of cytokine production GO:0001818 84 0.045
epithelial tube morphogenesis GO:0060562 303 0.045
regulation of killing of cells of other organism GO:0051709 4 0.044
regulation of immunoglobulin production in mucosal tissue GO:2000557 1 0.044
organophosphate catabolic process GO:0046434 232 0.044
response to radiation GO:0009314 165 0.044
purine nucleotide catabolic process GO:0006195 211 0.044
positive regulation of secretion GO:0051047 130 0.044
cellular divalent inorganic cation homeostasis GO:0072503 127 0.044
antimicrobial peptide production GO:0002775 2 0.044
Mouse
detection of fungus GO:0016046 2 0.044
regulation of protein transport GO:0051223 163 0.043
regulation of kinase activity GO:0043549 249 0.043
maintenance of location GO:0051235 89 0.043
neutrophil chemotaxis GO:0030593 36 0.043
divalent metal ion transport GO:0070838 172 0.043
cell activation involved in immune response GO:0002263 126 0.043
amide transport GO:0042886 138 0.043
Mouse
modification by host of symbiont morphology or physiology GO:0051851 12 0.043
regulation of endopeptidase activity GO:0052548 89 0.042
neutrophil mediated cytotoxicity GO:0070942 8 0.042
cellular response to growth factor stimulus GO:0071363 197 0.042
nucleoside triphosphate catabolic process GO:0009143 205 0.042
regulation of myoblast differentiation GO:0045661 29 0.041
positive regulation of dendritic cell dendrite assembly GO:2000549 1 0.041
regulation of protein kinase activity GO:0045859 232 0.041
positive regulation of lymphocyte activation GO:0051251 140 0.041
myotube differentiation GO:0014902 105 0.041
macromolecule catabolic process GO:0009057 281 0.041
Mouse
regulation of leukocyte proliferation GO:0070663 121 0.041
nucleotide catabolic process GO:0009166 217 0.041
negative regulation of myoblast differentiation GO:0045662 18 0.041
regulation of production of molecular mediator of immune response GO:0002700 65 0.041
positive regulation of b cell chemotaxis GO:2000538 2 0.041
regulation of natural killer cell chemotaxis GO:2000501 1 0.040
regulation of cell migration GO:0030334 219 0.040
Mouse
peptidyl amino acid modification GO:0018193 336 0.040
ion transmembrane transport GO:0034220 361 0.040
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.040
positive regulation of t helper 1 cell cytokine production GO:2000556 1 0.040
t helper 1 cell cytokine production GO:0035744 1 0.040
leukocyte activation involved in immune response GO:0002366 126 0.040
release of sequestered calcium ion into cytosol GO:0051209 42 0.039
negative regulation of muscle cell differentiation GO:0051148 33 0.039
muscle cell development GO:0055001 133 0.039
myotube cell development GO:0014904 60 0.039
positive regulation of phagocytosis GO:0050766 26 0.039
regulation of lymphocyte mediated immunity GO:0002706 84 0.039
regulation of proteolysis GO:0030162 164 0.038
skeletal system development GO:0001501 356 0.038
negative regulation of homeostatic process GO:0032845 71 0.038
regulation of response to biotic stimulus GO:0002831 38 0.038
circulatory system process GO:0003013 197 0.038
negative regulation of macrophage apoptotic process GO:2000110 3 0.038
regulation of cell motility GO:2000145 236 0.038
Mouse
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 16 0.038
positive regulation of leukocyte differentiation GO:1902107 86 0.038
developmental growth involved in morphogenesis GO:0060560 138 0.038
response to extracellular stimulus GO:0009991 127 0.038
cell surface pattern recognition receptor signaling pathway GO:0002752 2 0.038
regulation of calcium ion transport GO:0051924 69 0.038
ribonucleotide metabolic process GO:0009259 291 0.037
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.037
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.037
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.037
aromatic compound catabolic process GO:0019439 286 0.037
skeletal muscle fiber development GO:0048741 58 0.037
response to molecule of fungal origin GO:0002238 4 0.037
skeletal muscle organ development GO:0060538 163 0.037
cytosolic calcium ion transport GO:0060401 48 0.037
glycoprotein metabolic process GO:0009100 116 0.036
extrinsic apoptotic signaling pathway GO:0097191 126 0.036
regulation of intracellular transport GO:0032386 159 0.036
positive regulation of type 2 immune response GO:0002830 9 0.036
organic anion transport GO:0015711 137 0.036
glycosyl compound metabolic process GO:1901657 246 0.036
negative regulation of protein modification process GO:0031400 163 0.035
negative regulation of leukocyte proliferation GO:0070664 46 0.035
cytosolic calcium ion homeostasis GO:0051480 70 0.035
regulation of angiogenesis GO:0045765 81 0.035
epithelial cell proliferation GO:0050673 174 0.035
activation of immune response GO:0002253 138 0.035
b cell chemotaxis GO:0035754 3 0.035
stimulatory c type lectin receptor signaling pathway GO:0002223 2 0.035
regulation of membrane potential GO:0042391 192 0.035
protein processing GO:0016485 163 0.035
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.034
purine ribonucleoside metabolic process GO:0046128 241 0.034
purine ribonucleoside catabolic process GO:0046130 205 0.034
positive regulation of ras gtpase activity GO:0032320 65 0.034
t cell activation GO:0042110 289 0.034
purine nucleoside catabolic process GO:0006152 205 0.034
regulation of myotube differentiation GO:0010830 62 0.034
regulation of cysteine type endopeptidase activity GO:2000116 65 0.033
regulation of epithelial cell proliferation GO:0050678 141 0.033
response to ionizing radiation GO:0010212 42 0.033
g protein coupled receptor signaling pathway GO:0007186 243 0.033
neutrophil mediated killing of bacterium GO:0070944 6 0.033
membrane organization GO:0061024 245 0.033
single organism cell adhesion GO:0098602 156 0.033
carbohydrate metabolic process GO:0005975 230 0.033
negative regulation of cellular component organization GO:0051129 194 0.033
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.033
nucleoside phosphate catabolic process GO:1901292 222 0.033
regulation of metal ion transport GO:0010959 106 0.033
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.033
immunoglobulin production GO:0002377 73 0.033
wound healing GO:0042060 157 0.033
regulation of endocytosis GO:0030100 69 0.032
regulation of purine nucleotide metabolic process GO:1900542 169 0.032
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.032
cellular response to organonitrogen compound GO:0071417 145 0.032
Mouse
astrocyte cell migration GO:0043615 3 0.032
b cell mediated immunity GO:0019724 71 0.032
ribonucleotide catabolic process GO:0009261 208 0.032
myeloid leukocyte mediated immunity GO:0002444 42 0.032
ossification GO:0001503 216 0.032
purine nucleoside triphosphate metabolic process GO:0009144 226 0.031
regulation of transferase activity GO:0051338 263 0.031
positive regulation of stress activated mapk cascade GO:0032874 48 0.031
interleukin 12 secretion GO:0072610 3 0.031
regulation of protein secretion GO:0050708 82 0.031
positive regulation of proteolysis GO:0045862 85 0.031
cartilage development GO:0051216 140 0.030
cd4 positive alpha beta t cell proliferation GO:0035739 2 0.030
mature natural killer cell chemotaxis GO:0035782 1 0.030
modification of morphology or physiology of other organism GO:0035821 18 0.030
positive regulation of transferase activity GO:0051347 167 0.030
ribonucleoside triphosphate catabolic process GO:0009203 199 0.030
alpha beta t cell activation GO:0046631 91 0.030
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.030
peptide metabolic process GO:0006518 46 0.030
Mouse Rat
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.030
regulation of stress activated mapk cascade GO:0032872 69 0.030
neutrophil mediated killing of symbiont cell GO:0070943 8 0.029
endocytosis GO:0006897 168 0.029
Rat
eosinophil migration GO:0072677 3 0.029
regulation of protein localization GO:0032880 231 0.029
small gtpase mediated signal transduction GO:0007264 97 0.029
wound healing involved in inflammatory response GO:0002246 4 0.029
peptide secretion GO:0002790 114 0.029
Mouse
regulation of leukocyte apoptotic process GO:2000106 56 0.029
regulation of nucleotide metabolic process GO:0006140 169 0.029
neutrophil mediated killing of fungus GO:0070947 3 0.029
lymphocyte differentiation GO:0030098 242 0.029
cell adhesion GO:0007155 329 0.028
positive regulation of antimicrobial humoral response GO:0002760 2 0.028
response to inorganic substance GO:0010035 96 0.028
protein kinase b signaling GO:0043491 74 0.028
Mouse
ribonucleoside catabolic process GO:0042454 206 0.028
regulation of map kinase activity GO:0043405 120 0.028
neuron apoptotic process GO:0051402 142 0.028
positive regulation of map kinase activity GO:0043406 84 0.028
positive regulation of cell activation GO:0050867 158 0.028
cellular response to organic cyclic compound GO:0071407 87 0.028
multicellular organismal homeostasis GO:0048871 164 0.028
detection of stimulus GO:0051606 84 0.028
regulation of jnk cascade GO:0046328 62 0.028
regulation of cell projection organization GO:0031344 206 0.027
cdc42 protein signal transduction GO:0032488 0 0.027
regulation of t cell mediated immunity GO:0002709 34 0.027
positive regulation of protein kinase activity GO:0045860 144 0.027
regulation of cell adhesion GO:0030155 154 0.027
negative regulation of inflammatory response GO:0050728 61 0.027
positive regulation of chemotaxis GO:0050921 38 0.027
protein maturation GO:0051604 176 0.027
positive regulation of syncytium formation by plasma membrane fusion GO:0060143 17 0.027
regulation of leukocyte differentiation GO:1902105 159 0.027
hematopoietic stem cell proliferation GO:0071425 13 0.027
purine nucleoside metabolic process GO:0042278 241 0.027
nucleoside catabolic process GO:0009164 206 0.027
compound eye development GO:0048749 1 0.027
regulation of antimicrobial humoral response GO:0002759 3 0.027
negative regulation of protein phosphorylation GO:0001933 126 0.027
positive regulation of epithelial cell proliferation GO:0050679 68 0.026
regulation of hormone levels GO:0010817 211 0.026
positive regulation of inflammatory response GO:0050729 47 0.026
killing of cells in other organism involved in symbiotic interaction GO:0051883 13 0.026
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.026
cytokine secretion GO:0050663 72 0.026
antimicrobial peptide secretion GO:0002776 1 0.026
Mouse
killing of cells of other organism GO:0031640 13 0.026
positive regulation of secretion by cell GO:1903532 114 0.026
regulation of protein processing GO:0070613 96 0.026
cellular response to hormone stimulus GO:0032870 150 0.026
regulation of organelle organization GO:0033043 289 0.026
cation transmembrane transport GO:0098655 266 0.026
antibacterial peptide biosynthetic process GO:0002780 2 0.026
Mouse
intrinsic apoptotic signaling pathway GO:0097193 132 0.026
positive regulation of nucleotide catabolic process GO:0030813 88 0.026
renal system development GO:0072001 225 0.026
positive regulation of kinase activity GO:0033674 155 0.026
regulation of neuron apoptotic process GO:0043523 122 0.026
regulation of ossification GO:0030278 112 0.026
cellular response to dna damage stimulus GO:0006974 207 0.026
morphogenesis of a branching structure GO:0001763 203 0.026
regulation of purine nucleotide catabolic process GO:0033121 122 0.026
positive regulation of immunoglobulin production in mucosal tissue GO:2000558 1 0.026
cellular lipid metabolic process GO:0044255 323 0.025
myoblast differentiation GO:0045445 52 0.025
neuron death GO:0070997 154 0.025
peptide hormone secretion GO:0030072 109 0.025
innate immune response activating cell surface receptor signaling pathway GO:0002220 4 0.025
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.025
inorganic cation transmembrane transport GO:0098662 207 0.025
positive regulation of nucleotide metabolic process GO:0045981 114 0.025
kidney development GO:0001822 213 0.025
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.025
posttranscriptional regulation of gene expression GO:0010608 155 0.025
immunoglobulin mediated immune response GO:0016064 69 0.025
protein localization to organelle GO:0033365 185 0.025
positive regulation of myoblast differentiation GO:0045663 8 0.025
cell maturation GO:0048469 127 0.024
positive regulation of ion transport GO:0043270 65 0.024
dna metabolic process GO:0006259 303 0.024
positive regulation of interleukin 1 beta production GO:0032731 16 0.024
regulation of chemotaxis GO:0050920 53 0.024
Mouse
regulation of cytoplasmic transport GO:1903649 112 0.024
leukocyte apoptotic process GO:0071887 71 0.024
negative regulation of multi organism process GO:0043901 68 0.024
connective tissue development GO:0061448 179 0.024
response to transforming growth factor beta GO:0071559 88 0.024
second messenger mediated signaling GO:0019932 73 0.023
anatomical structure homeostasis GO:0060249 145 0.023
granulocyte migration GO:0097530 43 0.023
angiogenesis GO:0001525 201 0.023
regulation of vasculature development GO:1901342 88 0.023
tumor necrosis factor production GO:0032640 50 0.023
monocarboxylic acid transport GO:0015718 44 0.023
digestive system development GO:0055123 200 0.023
acute inflammatory response GO:0002526 41 0.023
negative regulation of lymphocyte activation GO:0051250 91 0.023
t cell mediated immunity GO:0002456 50 0.023
positive regulation of cell migration GO:0030335 109 0.023
cellular amide metabolic process GO:0043603 58 0.023
Mouse Rat
single organismal cell cell adhesion GO:0016337 131 0.022
skin development GO:0043588 220 0.022
positive regulation of response to biotic stimulus GO:0002833 15 0.022
regulation of dendritic cell dendrite assembly GO:2000547 2 0.022
regulation of blood pressure GO:0008217 93 0.022
urogenital system development GO:0001655 261 0.022
activation of mapk activity GO:0000187 59 0.022
positive regulation of cell projection organization GO:0031346 95 0.022
regulation of interleukin 1 production GO:0032652 26 0.022
extracellular structure organization GO:0043062 148 0.022
protein secretion GO:0009306 111 0.022
regulation of cellular component biogenesis GO:0044087 181 0.022
negative regulation of growth GO:0045926 99 0.022
positive regulation of apoptotic signaling pathway GO:2001235 95 0.021
lipid transport GO:0006869 98 0.021
regulation of vesicle mediated transport GO:0060627 139 0.021
response to nutrient levels GO:0031667 109 0.021
negative regulation of cellular amine metabolic process GO:0033239 1 0.021
positive regulation of cellular catabolic process GO:0031331 148 0.021
regulation of protein kinase b signaling GO:0051896 56 0.021
Mouse
positive regulation of adaptive immune response GO:0002821 61 0.021
response to steroid hormone GO:0048545 56 0.021
Rat
regulation of cytokine production involved in immune response GO:0002718 26 0.021
cellular response to external stimulus GO:0071496 88 0.021
glycoprotein biosynthetic process GO:0009101 89 0.021
regulation of cell projection assembly GO:0060491 38 0.021
antibacterial humoral response GO:0019731 8 0.020
Mouse
amino acid transport GO:0006865 61 0.020
male gamete generation GO:0048232 285 0.020
regulation of cell cycle GO:0051726 281 0.020
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.020
placenta development GO:0001890 140 0.020
positive regulation of cell motility GO:2000147 116 0.020
cellular response to interferon beta GO:0035458 21 0.020
negative regulation of hydrolase activity GO:0051346 71 0.020
positive regulation of neuron apoptotic process GO:0043525 25 0.020
regulation of intracellular protein transport GO:0033157 82 0.020

Mmp13 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.038
cancer DOID:162 0 0.031
disease of anatomical entity DOID:7 0 0.027
musculoskeletal system disease DOID:17 0 0.027
connective tissue disease DOID:65 0 0.027
organ system cancer DOID:0050686 0 0.024
nervous system disease DOID:863 0 0.021