Mus musculus

26 known processes

Oma1

OMA1 homolog, zinc metallopeptidase (S. cerevisiae)

(Aliases: ZMPOMA1,MPRP-1,2010001O09Rik)

Oma1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nucleobase containing small molecule metabolic process GO:0055086 352 0.104
dna metabolic process GO:0006259 303 0.099
cellular amino acid metabolic process GO:0006520 103 0.097
cellular amine metabolic process GO:0044106 44 0.089
amine metabolic process GO:0009308 45 0.085
regulation of cellular amino acid metabolic process GO:0006521 5 0.081
regulation of cellular ketone metabolic process GO:0010565 66 0.080
purine nucleotide metabolic process GO:0006163 302 0.080
oxidation reduction process GO:0055114 342 0.077
cellular ketone metabolic process GO:0042180 84 0.071
dna repair GO:0006281 107 0.069
nucleoside phosphate metabolic process GO:0006753 338 0.068
purine nucleoside triphosphate metabolic process GO:0009144 226 0.067
apoptotic signaling pathway GO:0097190 306 0.062
heterocycle catabolic process GO:0046700 280 0.058
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.058
peptidyl amino acid modification GO:0018193 336 0.057
nucleotide metabolic process GO:0009117 332 0.057
ribonucleotide metabolic process GO:0009259 291 0.056
purine containing compound metabolic process GO:0072521 311 0.056
cellular response to dna damage stimulus GO:0006974 207 0.055
nucleoside triphosphate metabolic process GO:0009141 230 0.055
purine nucleoside metabolic process GO:0042278 241 0.055
positive regulation of protein phosphorylation GO:0001934 242 0.054
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.053
purine ribonucleotide metabolic process GO:0009150 290 0.052
regulation of cellular amine metabolic process GO:0033238 20 0.050
nucleoside metabolic process GO:0009116 246 0.050
mapk cascade GO:0000165 281 0.050
cation transport GO:0006812 399 0.048
anatomical structure homeostasis GO:0060249 145 0.047
cellular nitrogen compound catabolic process GO:0044270 280 0.046
telomere maintenance GO:0000723 19 0.045
nucleoside monophosphate metabolic process GO:0009123 85 0.045
aromatic compound catabolic process GO:0019439 286 0.044
purine containing compound catabolic process GO:0072523 213 0.043
purine ribonucleoside metabolic process GO:0046128 241 0.043
cellular lipid metabolic process GO:0044255 323 0.043
transmembrane transport GO:0055085 412 0.043
glycosyl compound metabolic process GO:1901657 246 0.043
positive regulation of protein modification process GO:0031401 299 0.041
ribonucleoside metabolic process GO:0009119 245 0.040
nucleotide catabolic process GO:0009166 217 0.040
nucleoside triphosphate catabolic process GO:0009143 205 0.039
positive regulation of cellular amine metabolic process GO:0033240 5 0.039
negative regulation of phosphorylation GO:0042326 166 0.038
double strand break repair GO:0006302 48 0.038
nucleoside phosphate catabolic process GO:1901292 222 0.038
organophosphate catabolic process GO:0046434 232 0.037
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.037
organic cyclic compound catabolic process GO:1901361 295 0.036
ribonucleotide catabolic process GO:0009261 208 0.036
carbohydrate derivative catabolic process GO:1901136 231 0.036
purine nucleoside triphosphate catabolic process GO:0009146 203 0.035
cytokine production GO:0001816 319 0.035
striated muscle tissue development GO:0014706 293 0.035
purine ribonucleotide catabolic process GO:0009154 208 0.033
purine nucleoside catabolic process GO:0006152 205 0.032
negative regulation of cellular amine metabolic process GO:0033239 1 0.032
negative regulation of phosphate metabolic process GO:0045936 184 0.032
purine nucleotide catabolic process GO:0006195 211 0.032
ribonucleoside triphosphate catabolic process GO:0009203 199 0.031
muscle tissue development GO:0060537 308 0.031
organonitrogen compound catabolic process GO:1901565 264 0.031
dna recombination GO:0006310 92 0.031
cation transmembrane transport GO:0098655 266 0.031
regulation of transferase activity GO:0051338 263 0.031
synaptic transmission GO:0007268 329 0.030
immune effector process GO:0002252 321 0.030
macromolecule catabolic process GO:0009057 281 0.030
nucleoside catabolic process GO:0009164 206 0.030
negative regulation of molecular function GO:0044092 258 0.030
organonitrogen compound biosynthetic process GO:1901566 192 0.030
purine ribonucleoside catabolic process GO:0046130 205 0.029
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.029
intrinsic apoptotic signaling pathway GO:0097193 132 0.028
ras protein signal transduction GO:0007265 77 0.028
negative regulation of intracellular signal transduction GO:1902532 167 0.028
negative regulation of cellular protein metabolic process GO:0032269 247 0.028
regulation of protein localization GO:0032880 231 0.028
negative regulation of phosphorus metabolic process GO:0010563 184 0.028
cellular homeostasis GO:0019725 240 0.026
regulation of mapk cascade GO:0043408 248 0.026
regulation of kinase activity GO:0043549 249 0.026
coenzyme metabolic process GO:0006732 52 0.025
ion transmembrane transport GO:0034220 361 0.025
ribonucleoside triphosphate metabolic process GO:0009199 220 0.025
regulation of ion transport GO:0043269 215 0.025
regulation of cytokine production GO:0001817 266 0.025
regulation of organelle organization GO:0033043 289 0.025
small gtpase mediated signal transduction GO:0007264 97 0.024
atp metabolic process GO:0046034 75 0.024
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.024
purine nucleoside monophosphate metabolic process GO:0009126 81 0.024
ribonucleoside catabolic process GO:0042454 206 0.024
maintenance of location GO:0051235 89 0.023
cellular chemical homeostasis GO:0055082 215 0.023
regulation of cellular response to stress GO:0080135 159 0.023
regulation of protein kinase activity GO:0045859 232 0.023
microtubule based process GO:0007017 236 0.023
inorganic cation transmembrane transport GO:0098662 207 0.023
fatty acid metabolic process GO:0006631 121 0.022
negative regulation of protein modification process GO:0031400 163 0.022
epithelial tube morphogenesis GO:0060562 303 0.022
ribose phosphate metabolic process GO:0019693 291 0.021
regulation of secretion GO:0051046 274 0.021
glycosyl compound catabolic process GO:1901658 206 0.021
response to organonitrogen compound GO:0010243 246 0.021
carbohydrate metabolic process GO:0005975 230 0.021
cellular protein complex assembly GO:0043623 116 0.021
cellular metal ion homeostasis GO:0006875 151 0.021
chromatin modification GO:0016568 187 0.021
protein acylation GO:0043543 64 0.020
divalent inorganic cation transport GO:0072511 178 0.020
ribonucleoside monophosphate metabolic process GO:0009161 80 0.020
muscle cell differentiation GO:0042692 261 0.020
positive regulation of cell death GO:0010942 224 0.020
regulation of establishment of protein localization GO:0070201 181 0.020
regulation of apoptotic signaling pathway GO:2001233 197 0.020
reactive oxygen species metabolic process GO:0072593 84 0.020
regulation of membrane potential GO:0042391 192 0.020
homeostasis of number of cells GO:0048872 210 0.020
nitrogen compound transport GO:0071705 271 0.020
regulation of defense response GO:0031347 233 0.020
divalent metal ion transport GO:0070838 172 0.020
sensory perception GO:0007600 245 0.019
response to oxidative stress GO:0006979 123 0.019
regulation of cellular catabolic process GO:0031329 242 0.019
purine nucleoside monophosphate catabolic process GO:0009128 58 0.019
negative regulation of protein metabolic process GO:0051248 282 0.019
intracellular protein transport GO:0006886 204 0.019
response to organic cyclic compound GO:0014070 198 0.019
protein modification by small protein conjugation GO:0032446 187 0.019
cellular ion homeostasis GO:0006873 165 0.019
histone modification GO:0016570 159 0.019
atp catabolic process GO:0006200 55 0.019
regulation of anatomical structure size GO:0090066 178 0.019
cellular macromolecule catabolic process GO:0044265 206 0.019
cell type specific apoptotic process GO:0097285 268 0.019
protein ubiquitination GO:0016567 171 0.018
response to molecule of bacterial origin GO:0002237 143 0.018
positive regulation of proteolysis GO:0045862 85 0.018
negative regulation of immune system process GO:0002683 209 0.018
regulation of transmembrane transport GO:0034762 128 0.018
positive regulation of transferase activity GO:0051347 167 0.018
negative regulation of cellular component organization GO:0051129 194 0.018
positive regulation of apoptotic process GO:0043065 217 0.018
chromatin organization GO:0006325 206 0.018
regulation of hydrolase activity GO:0051336 246 0.018
nucleoside monophosphate catabolic process GO:0009125 59 0.018
regulation of secretion by cell GO:1903530 249 0.018
ear development GO:0043583 200 0.018
skeletal system development GO:0001501 356 0.018
inorganic ion transmembrane transport GO:0098660 234 0.018
spermatogenesis GO:0007283 284 0.017
circulatory system process GO:0003013 197 0.017
organelle localization GO:0051640 179 0.017
urogenital system development GO:0001655 261 0.017
sulfur compound metabolic process GO:0006790 100 0.017
cation homeostasis GO:0055080 212 0.017
protein processing GO:0016485 163 0.017
positive regulation of mapk cascade GO:0043410 170 0.017
calcium ion transport GO:0006816 159 0.017
regulation of interleukin 8 production GO:0032677 3 0.017
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.017
gland development GO:0048732 330 0.017
inflammatory response GO:0006954 244 0.017
protein maturation GO:0051604 176 0.017
neuron death GO:0070997 154 0.017
regulation of homeostatic process GO:0032844 182 0.017
metal ion homeostasis GO:0055065 189 0.017
organophosphate biosynthetic process GO:0090407 122 0.017
regulation of neuron differentiation GO:0045664 281 0.017
rna processing GO:0006396 105 0.016
locomotory behavior GO:0007626 195 0.016
dephosphorylation GO:0016311 129 0.016
positive regulation of kinase activity GO:0033674 155 0.016
cellular response to organonitrogen compound GO:0071417 145 0.016
protein modification by small protein conjugation or removal GO:0070647 207 0.016
innate immune response GO:0045087 157 0.016
adult behavior GO:0030534 135 0.016
cofactor metabolic process GO:0051186 80 0.016
response to lipopolysaccharide GO:0032496 128 0.016
cytoplasmic transport GO:0016482 234 0.016
leukocyte differentiation GO:0002521 342 0.016
negative regulation of protein phosphorylation GO:0001933 126 0.016
membrane organization GO:0061024 245 0.016
blood circulation GO:0008015 195 0.016
regulation of cell activation GO:0050865 289 0.016
positive regulation of programmed cell death GO:0043068 218 0.016
posttranscriptional regulation of gene expression GO:0010608 155 0.015
lipid biosynthetic process GO:0008610 179 0.015
regulation of protein transport GO:0051223 163 0.015
lymphocyte differentiation GO:0030098 242 0.015
regulation of hormone levels GO:0010817 211 0.015
canonical wnt signaling pathway GO:0060070 130 0.015
methylation GO:0032259 134 0.015
negative regulation of transferase activity GO:0051348 85 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.015
cellular response to cytokine stimulus GO:0071345 189 0.015
organic hydroxy compound metabolic process GO:1901615 203 0.015
positive regulation of protein kinase activity GO:0045860 144 0.015
regulation of reactive oxygen species metabolic process GO:2000377 40 0.015
cellular divalent inorganic cation homeostasis GO:0072503 127 0.015
regulation of proteolysis GO:0030162 164 0.015
anion transport GO:0006820 177 0.015
regulation of cell projection organization GO:0031344 206 0.015
production of molecular mediator of immune response GO:0002440 103 0.015
multicellular organismal homeostasis GO:0048871 164 0.015
sequestering of metal ion GO:0051238 19 0.015
multicellular organismal signaling GO:0035637 91 0.014
lipid localization GO:0010876 126 0.014
g protein coupled receptor signaling pathway GO:0007186 243 0.014
regulation of cellular component biogenesis GO:0044087 181 0.014
sequestering of calcium ion GO:0051208 18 0.014
gonad development GO:0008406 141 0.014
alpha amino acid metabolic process GO:1901605 59 0.014
organelle fission GO:0048285 170 0.014
positive regulation of cellular catabolic process GO:0031331 148 0.014
histone h4 k16 acetylation GO:0043984 3 0.014
protein localization to organelle GO:0033365 185 0.014
regulation of cell cycle GO:0051726 281 0.014
nuclear transport GO:0051169 139 0.014
nuclear division GO:0000280 158 0.014
response to extracellular stimulus GO:0009991 127 0.014
mitotic cell cycle process GO:1903047 159 0.014
positive regulation of hydrolase activity GO:0051345 148 0.014
interleukin 8 production GO:0032637 4 0.014
mitotic cell cycle GO:0000278 195 0.014
neuron apoptotic process GO:0051402 142 0.014
action potential GO:0001508 78 0.014
macromolecule methylation GO:0043414 120 0.014
fat cell differentiation GO:0045444 160 0.014
carbohydrate derivative biosynthetic process GO:1901137 183 0.013
transmission of nerve impulse GO:0019226 76 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.013
regulation of lymphocyte activation GO:0051249 240 0.013
male gamete generation GO:0048232 285 0.013
meiotic nuclear division GO:0007126 115 0.013
endocytosis GO:0006897 168 0.013
cellular calcium ion homeostasis GO:0006874 119 0.013
calcium ion homeostasis GO:0055074 127 0.013
defense response to other organism GO:0098542 197 0.013
covalent chromatin modification GO:0016569 163 0.013
positive regulation of interleukin 8 production GO:0032757 2 0.013
carboxylic acid biosynthetic process GO:0046394 86 0.013
multicellular organism growth GO:0035264 161 0.013
small molecule biosynthetic process GO:0044283 132 0.013
rho protein signal transduction GO:0007266 32 0.012
regulation of cytoplasmic transport GO:1903649 112 0.012
regulation of body fluid levels GO:0050878 162 0.012
compound eye development GO:0048749 1 0.012
positive regulation of secretion GO:0051047 130 0.012
rhythmic process GO:0048511 174 0.012
regulation of t cell activation GO:0050863 170 0.012
protein secretion GO:0009306 111 0.012
regulation of intracellular transport GO:0032386 159 0.012
forebrain development GO:0030900 302 0.012
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.012
negative regulation of apoptotic signaling pathway GO:2001234 104 0.012
kidney development GO:0001822 213 0.012
t cell activation GO:0042110 289 0.012
wnt signaling pathway GO:0016055 188 0.012
developmental maturation GO:0021700 193 0.012
regulation of cysteine type endopeptidase activity GO:2000116 65 0.012
divalent inorganic cation homeostasis GO:0072507 138 0.012
positive regulation of nervous system development GO:0051962 221 0.012
regulation of endopeptidase activity GO:0052548 89 0.012
regulation of protein serine threonine kinase activity GO:0071900 157 0.012
peptidyl tyrosine phosphorylation GO:0018108 143 0.012
germ cell development GO:0007281 185 0.012
response to acid chemical GO:0001101 111 0.012
lateral inhibition GO:0046331 1 0.012
synapsis GO:0007129 34 0.012
myeloid cell differentiation GO:0030099 233 0.012
peptidyl lysine modification GO:0018205 77 0.011
tissue homeostasis GO:0001894 115 0.011
ossification GO:0001503 216 0.011
peptidyl tyrosine modification GO:0018212 145 0.011
regulation of metal ion transport GO:0010959 106 0.011
b cell activation GO:0042113 161 0.011
response to radiation GO:0009314 165 0.011
cellular amide metabolic process GO:0043603 58 0.011
negative regulation of organelle organization GO:0010639 90 0.011
negative regulation of cell proliferation GO:0008285 296 0.011
tissue remodeling GO:0048771 102 0.011
epithelial cell proliferation GO:0050673 174 0.011
regulation of map kinase activity GO:0043405 120 0.011
positive regulation of cell development GO:0010720 237 0.011
neuronal action potential GO:0019228 54 0.011
extrinsic apoptotic signaling pathway GO:0097191 126 0.011
endomembrane system organization GO:0010256 147 0.011
cellular response to biotic stimulus GO:0071216 92 0.011
heart morphogenesis GO:0003007 178 0.011
renal system development GO:0072001 225 0.011
learning or memory GO:0007611 148 0.011
establishment of organelle localization GO:0051656 122 0.011
regulation of cell cycle process GO:0010564 160 0.011
cell division GO:0051301 120 0.011
mrna metabolic process GO:0016071 84 0.011
cellular response to lipid GO:0071396 145 0.011
protein polymerization GO:0051258 57 0.011
blood vessel morphogenesis GO:0048514 285 0.011
meiotic cell cycle GO:0051321 122 0.011
regulation of calcium ion transport GO:0051924 69 0.011
glycoprotein metabolic process GO:0009100 116 0.011
monocarboxylic acid catabolic process GO:0072329 27 0.011
microtubule cytoskeleton organization GO:0000226 157 0.011
regulation of blood pressure GO:0008217 93 0.011
lymphocyte proliferation GO:0046651 164 0.011
response to nutrient levels GO:0031667 109 0.011
chemotaxis GO:0006935 247 0.011
stress activated mapk cascade GO:0051403 80 0.011
mrna processing GO:0006397 63 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.011
leukocyte mediated immunity GO:0002443 174 0.011
regulation of neuron death GO:1901214 134 0.011
stress activated protein kinase signaling cascade GO:0031098 81 0.011
protein targeting GO:0006605 143 0.011
regulation of vesicle mediated transport GO:0060627 139 0.011
cellular response to oxidative stress GO:0034599 76 0.011
protein localization to nucleus GO:0034504 121 0.011
cytokine mediated signaling pathway GO:0019221 115 0.010
leukocyte activation involved in immune response GO:0002366 126 0.010
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.010
stem cell development GO:0048864 219 0.010
body fluid secretion GO:0007589 53 0.010
camera type eye development GO:0043010 266 0.010
meiotic cell cycle process GO:1903046 77 0.010
regulation of ion transmembrane transport GO:0034765 119 0.010
meiosis i GO:0007127 60 0.010
peptidyl serine phosphorylation GO:0018105 74 0.010
cellular response to hormone stimulus GO:0032870 150 0.010
glycosylation GO:0070085 62 0.010
mitochondrion organization GO:0007005 134 0.010
actin cytoskeleton organization GO:0030036 220 0.010
muscle system process GO:0003012 141 0.010
lymphocyte mediated immunity GO:0002449 139 0.010
substantia nigra development GO:0021762 2 0.010
stem cell differentiation GO:0048863 268 0.010
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.010
tube formation GO:0035148 140 0.010
cellular protein catabolic process GO:0044257 155 0.010
response to inorganic substance GO:0010035 96 0.010
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.010
cardiac muscle tissue development GO:0048738 130 0.010
dna catabolic process endonucleolytic GO:0000737 15 0.010
negative regulation of kinase activity GO:0033673 81 0.010
cellular response to cadmium ion GO:0071276 3 0.010
muscle contraction GO:0006936 101 0.010
vesicle localization GO:0051648 86 0.010
activation of immune response GO:0002253 138 0.010
regulation of neuron apoptotic process GO:0043523 122 0.010
adult locomotory behavior GO:0008344 91 0.010

Oma1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.036
nervous system disease DOID:863 0 0.036
central nervous system disease DOID:331 0 0.021
musculoskeletal system disease DOID:17 0 0.020
connective tissue disease DOID:65 0 0.018
sensory system disease DOID:0050155 0 0.014
bone disease DOID:0080001 0 0.014
disease of metabolism DOID:0014667 0 0.013
neurodegenerative disease DOID:1289 0 0.012
inherited metabolic disorder DOID:655 0 0.010