Mus musculus

175 known processes

Pou1f1

POU domain, class 1, transcription factor 1

(Aliases: Pit1-rs1,Pit-1,dwarf,Pit1,GHF-1,Hmp1,dw)

Pou1f1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein catabolic process GO:0030163 221 0.329
stem cell proliferation GO:0072089 117 0.269
gland development GO:0048732 330 0.242
positive regulation of cell development GO:0010720 237 0.214
striated muscle tissue development GO:0014706 293 0.181
Mouse
odontogenesis of dentin containing tooth GO:0042475 66 0.165
fertilization GO:0009566 127 0.142
divalent metal ion transport GO:0070838 172 0.118
organic hydroxy compound metabolic process GO:1901615 203 0.110
regulation of stem cell proliferation GO:0072091 78 0.104
regulation of cell motility GO:2000145 236 0.099
vitamin metabolic process GO:0006766 23 0.095
peptide transport GO:0015833 133 0.092
positive regulation of nervous system development GO:0051962 221 0.089
macromolecule catabolic process GO:0009057 281 0.083
cardiac muscle tissue morphogenesis GO:0055008 44 0.079
Mouse
connective tissue development GO:0061448 179 0.075
response to organonitrogen compound GO:0010243 246 0.070
regulation of muscle tissue development GO:1901861 97 0.068
cellular response to organonitrogen compound GO:0071417 145 0.066
cellular chemical homeostasis GO:0055082 215 0.066
cellular response to lipid GO:0071396 145 0.066
regulation of neural precursor cell proliferation GO:2000177 70 0.061
cellular ketone metabolic process GO:0042180 84 0.060
jak stat cascade GO:0007259 42 0.060
regulation of neuron differentiation GO:0045664 281 0.060
Mouse
positive regulation of stem cell proliferation GO:2000648 59 0.057
organonitrogen compound biosynthetic process GO:1901566 192 0.057
diencephalon development GO:0021536 63 0.055
response to amino acid GO:0043200 37 0.055
odontogenesis GO:0042476 78 0.054
endocrine system development GO:0035270 98 0.054
positive regulation of cell cycle GO:0045787 92 0.054
appendage development GO:0048736 166 0.053
muscle tissue development GO:0060537 308 0.052
Mouse
positive regulation of neural precursor cell proliferation GO:2000179 42 0.052
neuroblast proliferation GO:0007405 49 0.052
male sex differentiation GO:0046661 109 0.052
negative regulation of blood vessel endothelial cell migration GO:0043537 3 0.051
regulation of jak stat cascade GO:0046425 34 0.051
cellular response to acid chemical GO:0071229 68 0.051
cell type specific apoptotic process GO:0097285 268 0.049
Mouse
sensory perception GO:0007600 245 0.049
Mouse
sperm egg recognition GO:0035036 37 0.049
developmental growth involved in morphogenesis GO:0060560 138 0.046
Mouse
regionalization GO:0003002 337 0.046
skeletal muscle organ development GO:0060538 163 0.044
regulation of cellular component size GO:0032535 121 0.043
amine metabolic process GO:0009308 45 0.043
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.041
regulation of cellular ketone metabolic process GO:0010565 66 0.040
cation transport GO:0006812 399 0.040
negative regulation of cell development GO:0010721 169 0.037
hematopoietic progenitor cell differentiation GO:0002244 143 0.037
positive regulation of cell death GO:0010942 224 0.036
Mouse
stem cell development GO:0048864 219 0.036
Mouse
cellular homeostasis GO:0019725 240 0.036
amide transport GO:0042886 138 0.036
regulation of organ morphogenesis GO:2000027 144 0.036
response to oxygen levels GO:0070482 62 0.035
lipid transport GO:0006869 98 0.035
cellular metal ion homeostasis GO:0006875 151 0.035
skeletal muscle fiber development GO:0048741 58 0.035
metal ion homeostasis GO:0055065 189 0.035
cellular response to organic cyclic compound GO:0071407 87 0.035
apoptotic process involved in morphogenesis GO:0060561 25 0.035
oxidation reduction process GO:0055114 342 0.034
regulation of cellular amine metabolic process GO:0033238 20 0.034
cellular amine metabolic process GO:0044106 44 0.034
regulation of cell cycle GO:0051726 281 0.034
ameboidal type cell migration GO:0001667 128 0.033
regulation of cell migration GO:0030334 219 0.033
stem cell differentiation GO:0048863 268 0.032
Mouse
respiratory system development GO:0060541 190 0.032
Mouse
glial cell differentiation GO:0010001 131 0.032
Mouse
cell fate commitment GO:0045165 210 0.032
regulation of hormone levels GO:0010817 211 0.032
monocarboxylic acid transport GO:0015718 44 0.032
protein import GO:0017038 101 0.031
action potential GO:0001508 78 0.031
Mouse
cardiac ventricle development GO:0003231 83 0.030
Mouse
positive regulation of neuroblast proliferation GO:0002052 19 0.030
mammary gland morphogenesis GO:0060443 54 0.030
skeletal system morphogenesis GO:0048705 203 0.030
negative regulation of protein metabolic process GO:0051248 282 0.030
regulation of ion transport GO:0043269 215 0.030
protein activation cascade GO:0072376 19 0.030
oviduct development GO:0060066 3 0.030
neural precursor cell proliferation GO:0061351 121 0.029
Mouse
axon ensheathment GO:0008366 76 0.029
Mouse
regulation of ion transmembrane transport GO:0034765 119 0.028
granulocyte macrophage colony stimulating factor production GO:0032604 3 0.028
molting cycle GO:0042303 90 0.028
trachea cartilage morphogenesis GO:0060535 4 0.028
regulation of epithelial cell migration GO:0010632 35 0.028
mammary gland epithelium development GO:0061180 65 0.027
positive regulation of cell motility GO:2000147 116 0.027
forebrain development GO:0030900 302 0.027
positive regulation of cellular amine metabolic process GO:0033240 5 0.027
paramesonephric duct development GO:0061205 3 0.027
regulation of vitamin metabolic process GO:0030656 3 0.026
cellular response to amino acid stimulus GO:0071230 29 0.026
skin development GO:0043588 220 0.026
Mouse
response to molecule of bacterial origin GO:0002237 143 0.026
regulation of neuron projection development GO:0010975 169 0.026
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.026
cardiac chamber morphogenesis GO:0003206 93 0.026
Mouse
protein maturation GO:0051604 176 0.026
endocrine process GO:0050886 39 0.026
negative regulation of cell cycle GO:0045786 123 0.026
morphogenesis of a branching epithelium GO:0061138 193 0.026
cardiac cell fate determination GO:0060913 2 0.026
positive regulation of hormone metabolic process GO:0032352 3 0.025
purine containing compound metabolic process GO:0072521 311 0.025
divalent inorganic cation transport GO:0072511 178 0.025
regulation of wnt signaling pathway GO:0030111 123 0.025
posttranscriptional regulation of gene expression GO:0010608 155 0.025
neuroepithelial cell differentiation GO:0060563 37 0.025
hypophysis morphogenesis GO:0048850 3 0.025
response to growth factor GO:0070848 198 0.025
regulation of apoptotic signaling pathway GO:2001233 197 0.025
cation transmembrane transport GO:0098655 266 0.025
regulation of multi organism process GO:0043900 111 0.025
renal system process GO:0003014 48 0.024
binding of sperm to zona pellucida GO:0007339 34 0.024
spermatid differentiation GO:0048515 115 0.024
lipid biosynthetic process GO:0008610 179 0.024
negative regulation of lyase activity GO:0051350 1 0.024
nucleocytoplasmic transport GO:0006913 139 0.023
regulation of systemic arterial blood pressure by hormone GO:0001990 25 0.023
vitamin a metabolic process GO:0006776 2 0.023
muscle tissue morphogenesis GO:0060415 53 0.023
Mouse
regulation of neuroblast proliferation GO:1902692 27 0.023
steroid metabolic process GO:0008202 119 0.023
transmembrane transport GO:0055085 412 0.022
cell growth GO:0016049 130 0.022
Mouse
cell adhesion GO:0007155 329 0.022
positive regulation of mapk cascade GO:0043410 170 0.022
cellular response to peptide hormone stimulus GO:0071375 92 0.022
limb morphogenesis GO:0035108 149 0.022
cellular response to hormone stimulus GO:0032870 150 0.022
anatomical structure maturation GO:0071695 49 0.022
negative regulation of nervous system development GO:0051961 156 0.022
single fertilization GO:0007338 82 0.022
protein localization to organelle GO:0033365 185 0.022
regulation of protein maturation GO:1903317 96 0.022
regulation of hydrolase activity GO:0051336 246 0.021
small molecule biosynthetic process GO:0044283 132 0.021
male gamete generation GO:0048232 285 0.021
response to organic cyclic compound GO:0014070 198 0.021
sensory perception of mechanical stimulus GO:0050954 107 0.021
Mouse
cellular amino acid metabolic process GO:0006520 103 0.021
spermatogenesis GO:0007283 284 0.021
purine ribonucleotide metabolic process GO:0009150 290 0.021
cation homeostasis GO:0055080 212 0.021
regulation of transmembrane transport GO:0034762 128 0.021
regulation of steroid hormone biosynthetic process GO:0090030 4 0.020
regulation of protein processing GO:0070613 96 0.020
autonomic nervous system development GO:0048483 43 0.020
positive regulation of cell cycle process GO:0090068 61 0.020
nitrogen compound transport GO:0071705 271 0.020
tendon cell differentiation GO:0035990 4 0.020
epithelial cell migration GO:0010631 63 0.020
peripheral nervous system neuron axonogenesis GO:0048936 3 0.020
visceral motor neuron differentiation GO:0021524 3 0.020
regulation of interleukin 1 alpha production GO:0032650 4 0.020
cellular calcium ion homeostasis GO:0006874 119 0.020
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.020
branching morphogenesis of an epithelial tube GO:0048754 159 0.019
neuron death GO:0070997 154 0.019
Mouse
tube closure GO:0060606 91 0.019
noradrenergic neuron development GO:0003358 3 0.019
regulation of peptide transport GO:0090087 91 0.019
cellular lipid metabolic process GO:0044255 323 0.019
cytoplasmic transport GO:0016482 234 0.019
cerebellum development GO:0021549 77 0.019
cerebellar purkinje cell layer development GO:0021680 26 0.019
cell proliferation in external granule layer GO:0021924 10 0.019
cellular response to growth factor stimulus GO:0071363 197 0.019
regulation of dna binding GO:0051101 39 0.018
lymphocyte differentiation GO:0030098 242 0.018
positive regulation of lymphocyte activation GO:0051251 140 0.018
limb development GO:0060173 166 0.018
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.018
regulation of endothelial cell migration GO:0010594 22 0.018
regulation of transferase activity GO:0051338 263 0.018
cerebral cortex development GO:0021987 86 0.018
Mouse
extracellular matrix organization GO:0030198 147 0.018
regulation of protein localization GO:0032880 231 0.018
epithelial cell proliferation GO:0050673 174 0.018
keratinocyte proliferation GO:0043616 21 0.018
regulation of protein catabolic process GO:0042176 108 0.017
negative regulation of immune system process GO:0002683 209 0.017
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.017
detection of external stimulus GO:0009581 61 0.017
mammary gland duct morphogenesis GO:0060603 38 0.017
sensory perception of sound GO:0007605 97 0.017
Mouse
regulation of epithelial cell proliferation GO:0050678 141 0.017
positive regulation of protein modification process GO:0031401 299 0.017
regulation of protein secretion GO:0050708 82 0.017
response to light stimulus GO:0009416 135 0.017
mapk cascade GO:0000165 281 0.017
regulation of microvillus organization GO:0032530 3 0.017
regulation of lymphocyte activation GO:0051249 240 0.016
synaptic transmission GO:0007268 329 0.016
testosterone biosynthetic process GO:0061370 2 0.016
dephosphorylation GO:0016311 129 0.016
lipid localization GO:0010876 126 0.016
hormone secretion GO:0046879 128 0.016
ear development GO:0043583 200 0.016
Mouse
motor neuron migration GO:0097475 4 0.016
organic cyclic compound catabolic process GO:1901361 295 0.016
cellular response to peptide GO:1901653 92 0.016
endomembrane system organization GO:0010256 147 0.016
negative regulation of myoblast differentiation GO:0045662 18 0.016
negative regulation of epithelial cell proliferation GO:0050680 64 0.016
protein processing GO:0016485 163 0.016
myoblast differentiation GO:0045445 52 0.016
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.016
horizontal cell localization GO:0035852 1 0.016
negative regulation of cell migration GO:0030336 59 0.016
hindbrain development GO:0030902 128 0.015
Mouse
neuron migration GO:0001764 122 0.015
negative regulation of muscle cell differentiation GO:0051148 33 0.015
positive regulation of transferase activity GO:0051347 167 0.015
regulation of defense response GO:0031347 233 0.015
regulation of protein complex assembly GO:0043254 83 0.015
regulation of cell cycle process GO:0010564 160 0.015
regulation of skeletal muscle fiber development GO:0048742 36 0.015
epithelium migration GO:0090132 63 0.015
response to steroid hormone GO:0048545 56 0.015
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.015
regulation of ossification GO:0030278 112 0.015
nuclear transport GO:0051169 139 0.015
Rat
response to inorganic substance GO:0010035 96 0.015
negative regulation of response to wounding GO:1903035 77 0.015
response to hypoxia GO:0001666 58 0.015
positive regulation of neuron differentiation GO:0045666 141 0.015
calcium ion transport GO:0006816 159 0.015
ossification GO:0001503 216 0.015
g protein coupled receptor signaling pathway GO:0007186 243 0.015
cerebellar granule cell precursor proliferation GO:0021930 10 0.015
labyrinthine layer blood vessel development GO:0060716 21 0.014
renal system development GO:0072001 225 0.014
Mouse
multicellular organismal homeostasis GO:0048871 164 0.014
negative regulation of neuron differentiation GO:0045665 101 0.014
intracellular protein transport GO:0006886 204 0.014
regulation of cellular component biogenesis GO:0044087 181 0.014
respiratory tube development GO:0030323 167 0.014
cellular response to steroid hormone stimulus GO:0071383 33 0.014
carbohydrate homeostasis GO:0033500 128 0.014
regulation of proteolysis GO:0030162 164 0.014
response to extracellular stimulus GO:0009991 127 0.014
single organism nuclear import GO:1902593 95 0.014
positive regulation of mitotic cell cycle GO:0045931 41 0.014
spermatid development GO:0007286 108 0.014
endocytosis GO:0006897 168 0.014
muscle contraction GO:0006936 101 0.014
protein import into nucleus GO:0006606 95 0.014
fat soluble vitamin metabolic process GO:0006775 11 0.014
cytokine production GO:0001816 319 0.014
response to radiation GO:0009314 165 0.014
negative regulation of cellular protein metabolic process GO:0032269 247 0.014
gliogenesis GO:0042063 141 0.014
Mouse
positive regulation of hydrolase activity GO:0051345 148 0.014
regulation of cell projection organization GO:0031344 206 0.014
Mouse
dna metabolic process GO:0006259 303 0.014
cellular macromolecule catabolic process GO:0044265 206 0.014
interleukin 1 production GO:0032612 31 0.014
mitral valve morphogenesis GO:0003183 4 0.014
glucose homeostasis GO:0042593 128 0.014
oligopeptide transmembrane transport GO:0035672 4 0.014
regulation of cell growth GO:0001558 91 0.014
defense response to bacterium GO:0042742 119 0.014
cellular response to insulin stimulus GO:0032869 78 0.014
embryonic heart tube formation GO:0003144 1 0.014
negative regulation of protein maturation GO:1903318 79 0.014
fatty acid transport GO:0015908 28 0.013
positive regulation of growth GO:0045927 104 0.013
cell division GO:0051301 120 0.013
Mouse
maternal process involved in female pregnancy GO:0060135 32 0.013
skeletal system development GO:0001501 356 0.013
response to food GO:0032094 17 0.013
cellular response to carbohydrate stimulus GO:0071322 50 0.013
regulation of myoblast differentiation GO:0045661 29 0.013
response to acid chemical GO:0001101 111 0.013
Mouse
regulation of fat cell differentiation GO:0045598 81 0.013
bone morphogenesis GO:0060349 78 0.013
development of primary male sexual characteristics GO:0046546 88 0.013
negative regulation of neuron death GO:1901215 98 0.013
Mouse
neural tube closure GO:0001843 90 0.013
regulation of feeding behavior GO:0060259 3 0.013
nucleoside catabolic process GO:0009164 206 0.013
regulation of binding GO:0051098 111 0.013
extracellular structure organization GO:0043062 148 0.013
auditory receptor cell fate specification GO:0042667 1 0.013
lymphocyte proliferation GO:0046651 164 0.013
negative regulation of endothelial cell migration GO:0010596 4 0.013
leukocyte proliferation GO:0070661 172 0.013
negative regulation of multi organism process GO:0043901 68 0.013
ribose phosphate metabolic process GO:0019693 291 0.013
striated muscle cell development GO:0055002 125 0.013
regulation of cell size GO:0008361 72 0.013
heart morphogenesis GO:0003007 178 0.013
Mouse
nucleobase containing small molecule metabolic process GO:0055086 352 0.013
protein modification by small protein conjugation GO:0032446 187 0.013
placenta development GO:0001890 140 0.013
regulation of neuron death GO:1901214 134 0.013
Mouse
negative regulation of cell motility GO:2000146 61 0.013
maintenance of apical basal cell polarity GO:0035090 3 0.013
digestive tract morphogenesis GO:0048546 147 0.013
Mouse
protein localization to nucleus GO:0034504 121 0.013
myotube differentiation GO:0014902 105 0.013
amelogenesis GO:0097186 12 0.013
leukocyte differentiation GO:0002521 342 0.012
peptide secretion GO:0002790 114 0.012
regulation of cellular catabolic process GO:0031329 242 0.012
regulation of interleukin 6 production GO:0032675 55 0.012
trabecular meshwork development GO:0002930 2 0.012
epithelial tube formation GO:0072175 130 0.012
regulation of lymphocyte proliferation GO:0050670 117 0.012
bone development GO:0060348 120 0.012
neuron fate specification GO:0048665 30 0.012
Mouse
positive regulation of protein phosphorylation GO:0001934 242 0.012
calcium ion dependent exocytosis GO:0017156 35 0.012
Mouse
negative regulation of protein processing GO:0010955 79 0.012
gonad development GO:0008406 141 0.012
intrinsic apoptotic signaling pathway GO:0097193 132 0.012
canonical wnt signaling pathway GO:0060070 130 0.012
epidermis development GO:0008544 187 0.012
Mouse
regulation of inflammatory response GO:0050727 147 0.012
wnt signaling pathway GO:0016055 188 0.012
cellular nitrogen compound catabolic process GO:0044270 280 0.012
fat soluble vitamin biosynthetic process GO:0042362 4 0.012
regulation of thymocyte migration GO:2000410 2 0.012
sensory organ morphogenesis GO:0090596 242 0.012
Mouse
maintenance of epithelial cell apical basal polarity GO:0045199 2 0.012
regulation of gliogenesis GO:0014013 50 0.012
response to transforming growth factor beta GO:0071559 88 0.012
organic hydroxy compound transport GO:0015850 93 0.012
lung alveolus development GO:0048286 45 0.012
sympathetic ganglion development GO:0061549 9 0.012
blood vessel morphogenesis GO:0048514 285 0.011
trabecula formation GO:0060343 24 0.011
cell cell recognition GO:0009988 44 0.011
macrophage colony stimulating factor production GO:0036301 1 0.011
muscle cell differentiation GO:0042692 261 0.011
b cell activation GO:0042113 161 0.011
stem cell division GO:0017145 30 0.011
apoptotic signaling pathway GO:0097190 306 0.011
epithelial cell development GO:0002064 159 0.011
primary neural tube formation GO:0014020 95 0.011
nuclear import GO:0051170 95 0.011
somatic stem cell maintenance GO:0035019 47 0.011
regulation of auditory receptor cell differentiation GO:0045607 4 0.011
lung development GO:0030324 164 0.011
cellular response to molecule of bacterial origin GO:0071219 83 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.011
regulation of secretion by cell GO:1903530 249 0.011
Mouse
regulation of organelle organization GO:0033043 289 0.011
adenohypophysis development GO:0021984 14 0.011
establishment of protein localization to organelle GO:0072594 118 0.011
leukocyte apoptotic process GO:0071887 71 0.011
positive regulation of gliogenesis GO:0014015 27 0.011
regulation of leukocyte differentiation GO:1902105 159 0.011
positive regulation of angiogenesis GO:0045766 46 0.011
multi multicellular organism process GO:0044706 109 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.011
regulation of peptidase activity GO:0052547 96 0.011
dendrite development GO:0016358 115 0.011
spinal cord motor neuron migration GO:0097476 4 0.011
negative regulation of cellular component organization GO:0051129 194 0.011
tissue homeostasis GO:0001894 115 0.011
monocarboxylic acid metabolic process GO:0032787 191 0.011
regulation of steroid biosynthetic process GO:0050810 26 0.011
positive regulation of cell activation GO:0050867 158 0.011
negative regulation of adenylate cyclase activity GO:0007194 1 0.011
paraxial mesodermal cell fate commitment GO:0048343 2 0.011
peptidyl amino acid modification GO:0018193 336 0.011
semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:0071527 1 0.011
positive regulation of secretion GO:0051047 130 0.011
pancreatic pp cell fate commitment GO:0003329 2 0.011
learning or memory GO:0007611 148 0.011
mitral valve development GO:0003174 4 0.011
regulation of anterior head development GO:2000742 2 0.011
hormone metabolic process GO:0042445 86 0.011
embryonic placenta development GO:0001892 98 0.011
regulation of lymphocyte differentiation GO:0045619 107 0.011
regulation of mapk cascade GO:0043408 248 0.011
erythrocyte differentiation GO:0030218 88 0.010
negative regulation of phosphorus metabolic process GO:0010563 184 0.010
glycosyl compound catabolic process GO:1901658 206 0.010
keratinocyte migration GO:0051546 3 0.010
positive regulation of metanephric glomerulus development GO:0072300 4 0.010
regulation of myotube differentiation GO:0010830 62 0.010
response to iron ion GO:0010039 4 0.010
embryonic organ morphogenesis GO:0048562 276 0.010
Mouse
cardiac muscle cell differentiation GO:0055007 69 0.010
catecholamine metabolic process GO:0006584 30 0.010
regulation of translation GO:0006417 71 0.010
regulation of macrophage colony stimulating factor production GO:1901256 1 0.010
sclerotome development GO:0061056 4 0.010
regulation of morphogenesis of a branching structure GO:0060688 53 0.010
embryonic limb morphogenesis GO:0030326 126 0.010
cerebellum morphogenesis GO:0021587 42 0.010
response to nutrient levels GO:0031667 109 0.010
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 0.010
regulation of membrane potential GO:0042391 192 0.010
Mouse
planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:0061349 2 0.010

Pou1f1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.020
disease of cellular proliferation DOID:14566 0 0.020
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.018
sensory system disease DOID:0050155 0 0.018
eye and adnexa disease DOID:1492 0 0.012