Mus musculus

283 known processes

Rara

retinoic acid receptor, alpha

(Aliases: RARalpha1,RAR,Nr1b1)

Rara biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regionalization GO:0003002 337 0.999
Mouse
appendage morphogenesis GO:0035107 149 0.998
Mouse
regulation of female receptivity GO:0045924 6 0.997
Mouse
neural tube closure GO:0001843 90 0.996
embryonic organ morphogenesis GO:0048562 276 0.995
Mouse
morphogenesis of a branching epithelium GO:0061138 193 0.994
circadian temperature homeostasis GO:0060086 2 0.993
Mouse
limb development GO:0060173 166 0.993
appendage development GO:0048736 166 0.992
nephron tubule morphogenesis GO:0072078 68 0.990
epithelial tube morphogenesis GO:0060562 303 0.989
limb morphogenesis GO:0035108 149 0.989
Mouse
growth plate cartilage chondrocyte growth GO:0003430 2 0.987
Mouse
hindbrain development GO:0030902 128 0.985
Zebrafish
embryonic limb morphogenesis GO:0030326 126 0.983
Mouse
harderian gland development GO:0070384 2 0.982
Mouse
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.980
lung induction GO:0060492 3 0.979
neural crest cell migration involved in autonomic nervous system development GO:1901166 5 0.979
nephron epithelium morphogenesis GO:0072088 68 0.979
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.974
negative regulation of neuron differentiation GO:0045665 101 0.973
chondroblast differentiation GO:0060591 2 0.972
renal system development GO:0072001 225 0.972
morphogenesis of a branching structure GO:0001763 203 0.965
cardioblast migration to the midline involved in heart field formation GO:0060975 1 0.965
kidney epithelium development GO:0072073 121 0.963
negative regulation of translational initiation GO:0045947 4 0.960
negative regulation of axon extension GO:0030517 19 0.960
hindlimb morphogenesis GO:0035137 42 0.959
Mouse
planar cell polarity pathway involved in pericardium morphogenesis GO:0061354 2 0.959
growth plate cartilage chondrocyte development GO:0003431 3 0.959
Mouse
chondrocyte hypertrophy GO:0003415 4 0.958
Mouse
negative regulation of leukocyte differentiation GO:1902106 51 0.957
Human
neuron projection extension involved in neuron projection guidance GO:1902284 14 0.952
branching involved in ureteric bud morphogenesis GO:0001658 56 0.945
negative regulation of female receptivity GO:0007621 2 0.941
Mouse
stem cell maintenance GO:0019827 130 0.941
central nervous system neuron development GO:0021954 67 0.938
gliogenesis GO:0042063 141 0.937
ureteric bud morphogenesis GO:0060675 62 0.935
stem cell development GO:0048864 219 0.935
amine metabolic process GO:0009308 45 0.934
regulation of thyroid hormone mediated signaling pathway GO:0002155 3 0.932
Mouse
anterior commissure morphogenesis GO:0021960 6 0.930
mammary gland morphogenesis GO:0060443 54 0.927
renal tubule development GO:0061326 87 0.922
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.921
positive regulation of cellular amine metabolic process GO:0033240 5 0.919
subpallium neuron fate commitment GO:0060163 2 0.917
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.916
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.916
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.916
embryonic skeletal system morphogenesis GO:0048704 91 0.915
forebrain generation of neurons GO:0021872 63 0.915
somatic stem cell maintenance GO:0035019 47 0.909
olfactory bulb interneuron differentiation GO:0021889 12 0.902
subpallium development GO:0021544 20 0.900
Mouse
sensory organ morphogenesis GO:0090596 242 0.899
Mouse
pituitary gland development GO:0021983 38 0.895
metanephros development GO:0001656 79 0.895
retinal ganglion cell axon guidance GO:0031290 18 0.895
fibroblast proliferation GO:0048144 35 0.894
telencephalon development GO:0021537 186 0.893
Mouse
negative regulation of axon guidance GO:1902668 8 0.893
negative regulation of epithelial cell proliferation GO:0050680 64 0.891
regulation of neuron differentiation GO:0045664 281 0.891
oligodendrocyte differentiation GO:0048709 53 0.891
positive regulation of bile acid biosynthetic process GO:0070859 1 0.883
Mouse
glossopharyngeal nerve morphogenesis GO:0021615 4 0.882
forebrain neuron differentiation GO:0021879 52 0.881
endochondral bone morphogenesis GO:0060350 50 0.878
positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 18 0.877
neural tube formation GO:0001841 108 0.876
positive regulation of programmed cell death GO:0043068 218 0.876
Mouse
astrocyte differentiation GO:0048708 43 0.873
regulation of cardioblast differentiation GO:0051890 3 0.873
regulation of lipid catabolic process GO:0050994 15 0.871
Mouse
regulation of fibroblast proliferation GO:0048145 34 0.867
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 0.867
kidney morphogenesis GO:0060993 83 0.864
regulation of organ morphogenesis GO:2000027 144 0.864
cell fate commitment GO:0045165 210 0.864
smoothened signaling pathway GO:0007224 105 0.863
nephric duct formation GO:0072179 4 0.862
substrate dependent cerebral cortex tangential migration GO:0021825 3 0.858
t cell differentiation GO:0030217 174 0.857
Human
lateral mesoderm morphogenesis GO:0048369 3 0.855
olfactory bulb interneuron development GO:0021891 7 0.854
protein maturation GO:0051604 176 0.854
positive regulation of apoptotic process GO:0043065 217 0.851
Mouse
glial cell differentiation GO:0010001 131 0.849
neuron projection guidance GO:0097485 141 0.849
branching morphogenesis of an epithelial tube GO:0048754 159 0.844
mesonephric duct morphogenesis GO:0072180 4 0.842
urogenital system development GO:0001655 261 0.840
skeletal system morphogenesis GO:0048705 203 0.840
striatum development GO:0021756 14 0.839
Mouse
regulation of neuron projection development GO:0010975 169 0.839
midbrain hindbrain boundary maturation GO:0021732 1 0.836
cardioblast migration GO:0003260 1 0.835
positive regulation of female receptivity GO:0045925 3 0.835
Mouse
gastrulation GO:0007369 116 0.834
chondrocyte development GO:0002063 24 0.831
Mouse
regulation of nephron tubule epithelial cell differentiation GO:0072182 9 0.826
tube formation GO:0035148 140 0.825
germ cell development GO:0007281 185 0.821
midbrain hindbrain boundary morphogenesis GO:0021555 4 0.820
thyroid hormone mediated signaling pathway GO:0002154 3 0.820
Mouse
metanephric nephron tubule formation GO:0072289 4 0.818
mesenchyme development GO:0060485 152 0.816
sertoli cell fate commitment GO:0060010 1 0.814
chondrocyte differentiation GO:0002062 72 0.814
Mouse
positive regulation of steroid biosynthetic process GO:0010893 4 0.812
Mouse
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.812
translational initiation GO:0006413 24 0.810
gland development GO:0048732 330 0.809
Zebrafish Mouse
endochondral bone growth GO:0003416 19 0.804
epithelial cell proliferation GO:0050673 174 0.803
positive regulation of transcription via serum response element binding GO:0010735 1 0.803
negative regulation of protein metabolic process GO:0051248 282 0.801
axis elongation involved in somitogenesis GO:0090245 4 0.800
granulocyte differentiation GO:0030851 17 0.799
growth plate cartilage development GO:0003417 14 0.799
regulation of binding GO:0051098 111 0.795
Human
regulation of glial cell differentiation GO:0045685 41 0.795
negative regulation of immune system process GO:0002683 209 0.794
Human
negative regulation of cell cycle GO:0045786 123 0.792
embryonic hindlimb morphogenesis GO:0035116 32 0.786
Mouse
connective tissue development GO:0061448 179 0.786
digestive system development GO:0055123 200 0.785
cartilage development GO:0051216 140 0.783
cell proliferation in hindbrain GO:0021534 10 0.780
intrahepatic bile duct development GO:0035622 2 0.779
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus GO:1901522 7 0.778
mesonephric tubule development GO:0072164 94 0.775
cell migration to the midline involved in heart development GO:0003318 1 0.774
nephron morphogenesis GO:0072028 69 0.772
pallium development GO:0021543 120 0.768
regulation of apoptotic signaling pathway GO:2001233 197 0.768
female mating behavior GO:0060180 8 0.764
Mouse
axon guidance GO:0007411 141 0.763
cellular ketone metabolic process GO:0042180 84 0.763
Mouse
mammary gland epithelium development GO:0061180 65 0.763
cardiac right atrium morphogenesis GO:0003213 3 0.756
regulation of transcription from rna polymerase ii promoter involved in ventral spinal cord interneuron specification GO:0021913 4 0.753
response to leptin GO:0044321 7 0.747
Mouse
hypophysis morphogenesis GO:0048850 3 0.747
myeloid cell differentiation GO:0030099 233 0.745
skeletal system development GO:0001501 356 0.739
regulation of fat cell differentiation GO:0045598 81 0.739
Mouse
signal transduction involved in mitotic dna damage checkpoint GO:1902402 3 0.738
renal vesicle induction GO:0072034 3 0.736
digestive tract development GO:0048565 190 0.732
mesonephric epithelium development GO:0072163 94 0.732
nucleus accumbens development GO:0021768 1 0.729
brain morphogenesis GO:0048854 32 0.729
positive regulation of apoptotic signaling pathway GO:2001235 95 0.728
regulation of chondrocyte differentiation GO:0032330 33 0.726
Mouse
epithelial tube formation GO:0072175 130 0.724
regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072039 4 0.723
glandular epithelial cell differentiation GO:0002067 38 0.722
hindbrain formation GO:0021576 1 0.720
hindbrain tangential cell migration GO:0021934 2 0.719
neuron projection extension GO:1990138 64 0.719
erythrocyte differentiation GO:0030218 88 0.718
Mouse
forebrain development GO:0030900 302 0.715
Mouse
development of primary sexual characteristics GO:0045137 143 0.712
dna metabolic process GO:0006259 303 0.711
stem cell differentiation GO:0048863 268 0.710
mesonephric tubule morphogenesis GO:0072171 63 0.706
central nervous system projection neuron axonogenesis GO:0021952 21 0.696
regulation of transcription involved in primary germ layer cell fate commitment GO:0060796 2 0.696
bone morphogenesis GO:0060349 78 0.694
positive regulation of cell death GO:0010942 224 0.694
Mouse
kidney development GO:0001822 213 0.693
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.693
negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072040 4 0.692
olfactory lobe development GO:0021988 32 0.685
mesenchymal cell differentiation GO:0048762 107 0.683
neuroblast differentiation GO:0014016 2 0.680
regulation of cellular ketone metabolic process GO:0010565 66 0.679
Mouse
regulation of mesenchymal cell proliferation GO:0010464 37 0.678
spinal cord development GO:0021510 81 0.677
negative regulation of cellular protein metabolic process GO:0032269 247 0.677
zygotic determination of anterior posterior axis embryo GO:0007354 3 0.677
diencephalon development GO:0021536 63 0.671
skeletal muscle organ development GO:0060538 163 0.670
Mouse
embryonic appendage morphogenesis GO:0035113 126 0.670
Mouse
positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0072108 3 0.670
negative regulation of cell proliferation GO:0008285 296 0.669
Mouse
ventral spinal cord interneuron fate commitment GO:0060579 14 0.666
lipid homeostasis GO:0055088 63 0.665
Mouse
bone development GO:0060348 120 0.662
mesenchymal cell apoptotic process involved in nephron morphogenesis GO:1901145 4 0.659
auditory receptor cell fate determination GO:0042668 3 0.656
metanephric cap mesenchymal cell proliferation involved in metanephros development GO:0090094 2 0.656
neural tube patterning GO:0021532 43 0.653
limbic system development GO:0021761 72 0.651
ventricular septum morphogenesis GO:0060412 27 0.648
regulation of transcription factor import into nucleus GO:0042990 24 0.648
Mouse
cerebellar granule cell precursor proliferation GO:0021930 10 0.644
positive regulation of cholesterol homeostasis GO:2000189 2 0.642
regulation of myeloid leukocyte differentiation GO:0002761 58 0.640
rostrocaudal neural tube patterning GO:0021903 12 0.640
female courtship behavior GO:0008050 3 0.638
Mouse
pyramidal neuron migration GO:0021852 1 0.634
forelimb morphogenesis GO:0035136 40 0.633
embryonic viscerocranium morphogenesis GO:0048703 8 0.632
translation GO:0006412 93 0.631
negative regulation of apoptotic signaling pathway GO:2001234 104 0.631
regulation of bmp signaling pathway GO:0030510 60 0.629
metanephric comma shaped body morphogenesis GO:0072278 1 0.623
embryonic forelimb morphogenesis GO:0035115 32 0.622
regulation of cytokine production GO:0001817 266 0.621
Human
type i pneumocyte differentiation GO:0060509 7 0.620
Mouse
negative regulation of bmp signaling pathway GO:0030514 35 0.619
apoptotic signaling pathway GO:0097190 306 0.614
ureteric bud development GO:0001657 94 0.611
forebrain regionalization GO:0021871 25 0.605
planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:0061349 2 0.604
peptidyl amino acid modification GO:0018193 336 0.603
trachea formation GO:0060440 3 0.601
heart field specification GO:0003128 6 0.599
clara cell differentiation GO:0060486 4 0.599
somitogenesis GO:0001756 69 0.598
positive regulation of neuron differentiation GO:0045666 141 0.598
growth plate cartilage chondrocyte differentiation GO:0003418 5 0.598
Mouse
cerebellar cortex morphogenesis GO:0021696 32 0.597
lateral mesodermal cell differentiation GO:0048371 3 0.597
cartilage development involved in endochondral bone morphogenesis GO:0060351 24 0.596
trachea cartilage morphogenesis GO:0060535 4 0.596
midbrain hindbrain boundary development GO:0030917 9 0.591
kidney rudiment formation GO:0072003 3 0.591
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.590
mesonephros development GO:0001823 97 0.588
negative regulation of intracellular protein transport GO:0090317 27 0.585
Mouse
negative regulation of myeloid leukocyte differentiation GO:0002762 20 0.585
Human
lung cell differentiation GO:0060479 30 0.585
Mouse
hypothalamus development GO:0021854 16 0.584
regulation of cholesterol homeostasis GO:2000188 9 0.583
Mouse
mesonephric tubule formation GO:0072172 11 0.582
foregut regionalization GO:0060423 3 0.582
nodal signaling pathway involved in determination of left right asymmetry GO:0038107 2 0.582
negative regulation of mesodermal cell fate specification GO:0042662 3 0.580
protein processing GO:0016485 163 0.578
metencephalon development GO:0022037 89 0.575
cell type specific apoptotic process GO:0097285 268 0.575
Mouse
midgut development GO:0007494 4 0.575
specification of organ identity GO:0010092 30 0.574
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 5 0.572
negative regulation of wnt signaling pathway involved in heart development GO:0003308 4 0.571
cellular response to lipid GO:0071396 145 0.571
odontogenesis GO:0042476 78 0.571
axon extension involved in axon guidance GO:0048846 14 0.569
ureter morphogenesis GO:0072197 4 0.563
mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003337 9 0.557
male gamete generation GO:0048232 285 0.557
embryonic skeletal joint morphogenesis GO:0060272 11 0.557
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.556
bronchus development GO:0060433 10 0.552
organ induction GO:0001759 21 0.551
carbohydrate homeostasis GO:0033500 128 0.549
Mouse
extrinsic apoptotic signaling pathway GO:0097191 126 0.549
neuroblast proliferation GO:0007405 49 0.543
cell cycle arrest GO:0007050 37 0.543
protein localization to organelle GO:0033365 185 0.542
Mouse
atrial septum primum morphogenesis GO:0003289 3 0.542
response to retinoic acid GO:0032526 56 0.541
regulation of stem cell proliferation GO:0072091 78 0.539
trachea cartilage development GO:0060534 8 0.538
ossification GO:0001503 216 0.537
Mouse
embryonic digit morphogenesis GO:0042733 56 0.537
glandular epithelial cell development GO:0002068 15 0.530
polarity specification of proximal distal axis GO:0010085 2 0.529
apoptotic process involved in patterning of blood vessels GO:1902262 6 0.526
closure of optic fissure GO:0061386 2 0.523
odontogenesis of dentin containing tooth GO:0042475 66 0.521
positive regulation of hydrolase activity GO:0051345 148 0.520
digestive tract morphogenesis GO:0048546 147 0.517
metanephric nephron tubule epithelial cell differentiation GO:0072257 5 0.514
positive regulation of endopeptidase activity GO:0010950 43 0.511
regulation of cell migration GO:0030334 219 0.510
prostate gland morphogenesis GO:0060512 32 0.509
Mouse
regulation of endodermal cell differentiation GO:1903224 2 0.508
planar cell polarity pathway involved in outflow tract morphogenesis GO:0061347 2 0.508
signal transduction involved in dna damage checkpoint GO:0072422 3 0.504
energy homeostasis GO:0097009 15 0.504
Mouse
t cell differentiation in thymus GO:0033077 77 0.503
regulation of skeletal muscle fiber development GO:0048742 36 0.502
outflow tract morphogenesis GO:0003151 53 0.501
metanephric tubule development GO:0072170 18 0.501
macromolecule catabolic process GO:0009057 281 0.500
Mouse
astrocyte fate commitment GO:0060018 4 0.495
primary neural tube formation GO:0014020 95 0.495
striated muscle tissue development GO:0014706 293 0.494
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.494
muscle fiber development GO:0048747 76 0.492
mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis GO:0072309 3 0.491
female genitalia morphogenesis GO:0048807 3 0.484
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.483
forebrain morphogenesis GO:0048853 17 0.483
columnar cuboidal epithelial cell development GO:0002066 29 0.480
meiotic cell cycle GO:0051321 122 0.478
trachea morphogenesis GO:0060439 8 0.478
regulation of chromatin modification GO:1903308 57 0.478
cerebral cortex development GO:0021987 86 0.477
negative regulation of cartilage development GO:0061037 17 0.477
negative regulation of intracellular transport GO:0032387 38 0.475
Mouse
negative regulation of cell cycle process GO:0010948 69 0.475
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.473
spermatogenesis GO:0007283 284 0.470
regulation of endopeptidase activity GO:0052548 89 0.470
midbrain hindbrain boundary maturation during brain development GO:0022004 1 0.469
response to cold GO:0009409 19 0.468
Mouse
cerebellum development GO:0021549 77 0.467
ear morphogenesis GO:0042471 118 0.466
regulation of circadian rhythm GO:0042752 58 0.466
Mouse
chondrocyte differentiation involved in endochondral bone morphogenesis GO:0003413 7 0.466
Mouse
nephron epithelium development GO:0072009 92 0.464
stem cell proliferation GO:0072089 117 0.463
central nervous system vasculogenesis GO:0022009 3 0.460
generation of precursor metabolites and energy GO:0006091 103 0.458
Mouse
cerebellar cortex development GO:0021695 48 0.458
exocrine system development GO:0035272 45 0.457
Mouse
male sex differentiation GO:0046661 109 0.457
positive regulation of leukocyte apoptotic process GO:2000108 21 0.455
positive regulation of peptidase activity GO:0010952 49 0.454
embryonic heart tube anterior posterior pattern specification GO:0035054 3 0.454
cell division GO:0051301 120 0.453
fused antrum stage GO:0048165 1 0.452
tongue development GO:0043586 18 0.451
regulation of neural precursor cell proliferation GO:2000177 70 0.451
protein localization to nucleus GO:0034504 121 0.450
Mouse
central nervous system neuron differentiation GO:0021953 162 0.450
signal transduction in absence of ligand GO:0038034 55 0.449
posttranscriptional regulation of gene expression GO:0010608 155 0.449
negative regulation of dna replication GO:0008156 4 0.449
regulation of cell cycle process GO:0010564 160 0.446
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.442
developmental cell growth GO:0048588 84 0.441
Mouse
central nervous system morphogenesis GO:0021551 2 0.440
regulation of granulocyte differentiation GO:0030852 8 0.440
mammary gland duct morphogenesis GO:0060603 38 0.438
regulation of cellular amine metabolic process GO:0033238 20 0.435
rhombomere 3 morphogenesis GO:0021658 2 0.435
positive regulation of transcription by glucose GO:0046016 3 0.433
positive regulation of secondary heart field cardioblast proliferation GO:0072513 4 0.430
gonad development GO:0008406 141 0.424
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 0.419
nephron tubule formation GO:0072079 20 0.419
regulation of translation GO:0006417 71 0.418
cardiac muscle cell differentiation GO:0055007 69 0.417
metanephric nephron epithelium development GO:0072243 19 0.417
positive regulation of mesenchymal cell proliferation GO:0002053 33 0.415
negative regulation of cell growth GO:0030308 44 0.415
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.412
positive regulation of lymphocyte apoptotic process GO:0070230 13 0.411
positive regulation of lipid biosynthetic process GO:0046889 18 0.410
Mouse
skin morphogenesis GO:0043589 38 0.408
negative regulation of nucleocytoplasmic transport GO:0046823 23 0.406
Mouse
postganglionic parasympathetic nervous system development GO:0021784 2 0.406
spinal cord dorsal ventral patterning GO:0021513 23 0.404
negative regulation of cytoplasmic transport GO:1903650 29 0.404
Mouse
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902043 13 0.403
regulation of cartilage development GO:0061035 44 0.402
dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 3 0.402
cartilage condensation GO:0001502 18 0.401
Mouse
regulation of mitotic cell cycle phase transition GO:1901990 73 0.400
positive regulation of skeletal muscle tissue regeneration GO:0043415 4 0.400
regulation of transcription involved in cell fate commitment GO:0060850 15 0.398
planar cell polarity pathway involved in ventricular septum morphogenesis GO:0061348 2 0.398
pigment cell differentiation GO:0050931 27 0.397
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 0.396
ascending aorta morphogenesis GO:0035910 3 0.396
regulation of nucleocytoplasmic transport GO:0046822 73 0.396
Mouse
regulation of osteoblast differentiation GO:0045667 67 0.396
myeloid leukocyte differentiation GO:0002573 119 0.396
positive regulation of odontogenesis GO:0042482 4 0.394
canonical wnt signaling pathway involved in regulation of cell proliferation GO:0044340 3 0.394
negative regulation of photoreceptor cell differentiation GO:0046533 4 0.393
hematopoietic progenitor cell differentiation GO:0002244 143 0.393
positive regulation of neuron projection development GO:0010976 79 0.393
renal vesicle development GO:0072087 17 0.391
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.391
negative regulation of glial cell differentiation GO:0045686 21 0.390
signal transduction involved in mitotic g1 dna damage checkpoint GO:0072431 3 0.386
organ growth GO:0035265 117 0.381
negative regulation of fibroblast proliferation GO:0048147 14 0.380
modulation by virus of host morphology or physiology GO:0019048 3 0.378
chondrocyte development involved in endochondral bone morphogenesis GO:0003433 5 0.378
Mouse
signal transduction involved in mitotic dna integrity checkpoint GO:1902403 3 0.378
schwann cell differentiation GO:0014037 26 0.377
establishment of planar polarity involved in neural tube closure GO:0090177 15 0.377
membrane organization GO:0061024 245 0.377
cell aggregation GO:0098743 18 0.376
Mouse
muscle tissue development GO:0060537 308 0.375
positive regulation of thymocyte apoptotic process GO:0070245 5 0.375
metanephros morphogenesis GO:0003338 24 0.374
cellular amino acid metabolic process GO:0006520 103 0.374
regulation of branching involved in ureteric bud morphogenesis GO:0090189 22 0.373
establishment of planar polarity involved in nephron morphogenesis GO:0072046 1 0.373
anterior posterior axis specification embryo GO:0008595 9 0.372
negative regulation of neuron projection development GO:0010977 50 0.371
organelle localization GO:0051640 179 0.370
determination of left right symmetry GO:0007368 80 0.368
lung epithelial cell differentiation GO:0060487 29 0.367
Mouse
lung epithelium development GO:0060428 37 0.364
Mouse
multi multicellular organism process GO:0044706 109 0.358
Mouse
negative regulation of mesenchymal cell proliferation GO:0072201 3 0.358
secondary heart field specification GO:0003139 6 0.355
positive regulation of chromatin modification GO:1903310 28 0.355
metanephric cap development GO:0072185 2 0.355
peripheral nervous system neuron axonogenesis GO:0048936 3 0.355
axonogenesis GO:0007409 274 0.355
somatotropin secreting cell differentiation GO:0060126 4 0.351
cardiac endothelial cell differentiation GO:0003348 4 0.351
rhombomere 5 development GO:0021571 4 0.350
mesangial cell differentiation GO:0072007 4 0.350
lung field specification GO:0060424 3 0.349
peripheral nervous system development GO:0007422 53 0.347
epithelium migration GO:0090132 63 0.346
cellular response to oxidative stress GO:0034599 76 0.345
lipid catabolic process GO:0016042 69 0.343
Mouse
rhombomere 6 development GO:0021572 1 0.343
metanephric mesenchyme morphogenesis GO:0072133 4 0.342
negative regulation of myeloid cell differentiation GO:0045638 38 0.341
Human
signal transduction involved in dna integrity checkpoint GO:0072401 3 0.340
forebrain neuroblast division GO:0021873 9 0.339
otic placode formation GO:0043049 1 0.339
cerebellum formation GO:0021588 1 0.339
histone acetylation GO:0016573 41 0.338
cranial nerve structural organization GO:0021604 13 0.338
regulation of stem cell differentiation GO:2000736 50 0.337
embryonic epithelial tube formation GO:0001838 130 0.336
muscle cell differentiation GO:0042692 261 0.336
positive regulation of transcription from rna polymerase ii promoter by glucose GO:0000432 3 0.335
retinoic acid receptor signaling pathway GO:0048384 17 0.333
mitotic cell cycle GO:0000278 195 0.333
tertiary branching involved in mammary gland duct morphogenesis GO:0060748 3 0.333
lymphocyte apoptotic process GO:0070227 54 0.332
leukocyte differentiation GO:0002521 342 0.330
establishment of endothelial blood brain barrier GO:0014045 3 0.330
sympathetic nervous system development GO:0048485 22 0.327
circulatory system process GO:0003013 197 0.327
Mouse
regulation of ossification GO:0030278 112 0.325
negative regulation of endodermal cell differentiation GO:1903225 1 0.325
metanephric nephron tubule development GO:0072234 16 0.324
bmp signaling pathway GO:0030509 93 0.323
metanephric glomerulus development GO:0072224 13 0.323
salivary gland morphogenesis GO:0007435 33 0.323
regulation of axon extension GO:0030516 43 0.319
inflammatory response GO:0006954 244 0.319
Mouse
metanephric epithelium development GO:0072207 21 0.319
forebrain anterior posterior pattern specification GO:0021797 5 0.318
cloacal septation GO:0060197 2 0.317
nephron tubule development GO:0072080 84 0.317
brain segmentation GO:0035284 3 0.315
positive regulation of nervous system development GO:0051962 221 0.315
negative regulation of cell fate specification GO:0009996 4 0.314
kidney mesenchyme morphogenesis GO:0072131 4 0.314
commissural neuron axon guidance GO:0071679 8 0.313
tube closure GO:0060606 91 0.312
regulation of cell cycle phase transition GO:1901987 77 0.312
anatomical structure arrangement GO:0048532 20 0.312
myotube cell development GO:0014904 60 0.311
sinoatrial node cell differentiation GO:0060921 3 0.311
spinal cord patterning GO:0021511 25 0.310
leukocyte apoptotic process GO:0071887 71 0.309
regulation of cellular catabolic process GO:0031329 242 0.309
prostate gland epithelium morphogenesis GO:0060740 31 0.308
Mouse
meiotic nuclear division GO:0007126 115 0.307
regulation of lateral mesodermal cell fate specification GO:0048378 2 0.306
regulation of cell cycle GO:0051726 281 0.306
Human
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.306
Human
epithelial cell development GO:0002064 159 0.306
angiogenesis GO:0001525 201 0.304
mitotic g1 dna damage checkpoint GO:0031571 4 0.301
rhythmic process GO:0048511 174 0.301
Mouse
bile acid metabolic process GO:0008206 17 0.299
Mouse
carbon catabolite regulation of transcription from rna polymerase ii promoter GO:0000429 4 0.299
retina development in camera type eye GO:0060041 119 0.298
Mouse
embryonic heart tube development GO:0035050 65 0.298
metanephric mesenchymal cell differentiation GO:0072162 3 0.297
facial nucleus development GO:0021754 2 0.297
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.297
rhombomere development GO:0021546 8 0.295
embryonic skeletal system development GO:0048706 120 0.293
negative regulation of stem cell proliferation GO:2000647 12 0.292
common partner smad protein phosphorylation GO:0007182 2 0.290
regulation of t cell differentiation GO:0045580 83 0.290
Human
cellular response to x ray GO:0071481 2 0.290
regulation of protein import into nucleus GO:0042306 52 0.289
Mouse
heart induction GO:0003129 2 0.289
negative regulation of astrocyte differentiation GO:0048712 10 0.289
diencephalon morphogenesis GO:0048852 6 0.289
development of primary male sexual characteristics GO:0046546 88 0.288

Rara disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.631
disease of cellular proliferation DOID:14566 0 0.631