Mus musculus

0 known processes

Pde4c

phosphodiesterase 4C, cAMP specific

(Aliases: MGC31320,dunce,Dpde1,E130301F19Rik)

Pde4c biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular amine metabolic process GO:0033238 20 0.062
cellular ketone metabolic process GO:0042180 84 0.058
cellular homeostasis GO:0019725 240 0.056
regulation of cellular ketone metabolic process GO:0010565 66 0.053
cellular amino acid metabolic process GO:0006520 103 0.049
mapk cascade GO:0000165 281 0.045
regulation of cellular amino acid metabolic process GO:0006521 5 0.044
ion transmembrane transport GO:0034220 361 0.040
ossification GO:0001503 216 0.039
cytokine production GO:0001816 319 0.039
regulation of mapk cascade GO:0043408 248 0.039
cellular amine metabolic process GO:0044106 44 0.038
cation transport GO:0006812 399 0.038
gland development GO:0048732 330 0.037
transmembrane transport GO:0055085 412 0.036
leukocyte differentiation GO:0002521 342 0.036
lymphocyte differentiation GO:0030098 242 0.035
amine metabolic process GO:0009308 45 0.035
sensory perception GO:0007600 245 0.035
Mouse
positive regulation of protein modification process GO:0031401 299 0.034
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.034
cation transmembrane transport GO:0098655 266 0.033
apoptotic signaling pathway GO:0097190 306 0.033
embryonic organ morphogenesis GO:0048562 276 0.032
inorganic cation transmembrane transport GO:0098662 207 0.032
skeletal system development GO:0001501 356 0.031
negative regulation of cell proliferation GO:0008285 296 0.031
response to organonitrogen compound GO:0010243 246 0.030
synaptic transmission GO:0007268 329 0.030
Fly
positive regulation of cellular amine metabolic process GO:0033240 5 0.030
striated muscle tissue development GO:0014706 293 0.029
muscle tissue development GO:0060537 308 0.029
cellular chemical homeostasis GO:0055082 215 0.029
sensory organ morphogenesis GO:0090596 242 0.029
camera type eye development GO:0043010 266 0.029
kidney development GO:0001822 213 0.028
purine containing compound metabolic process GO:0072521 311 0.028
Rat
nucleoside phosphate metabolic process GO:0006753 338 0.028
Rat
response to lipopolysaccharide GO:0032496 128 0.027
regulation of secretion GO:0051046 274 0.027
Rat
inorganic ion transmembrane transport GO:0098660 234 0.026
regulation of lymphocyte activation GO:0051249 240 0.026
cellular nitrogen compound catabolic process GO:0044270 280 0.026
Rat
cytoplasmic transport GO:0016482 234 0.026
cellular lipid metabolic process GO:0044255 323 0.026
ras protein signal transduction GO:0007265 77 0.026
small gtpase mediated signal transduction GO:0007264 97 0.025
organ growth GO:0035265 117 0.025
male gamete generation GO:0048232 285 0.025
cellular response to lipid GO:0071396 145 0.025
regulation of organelle organization GO:0033043 289 0.025
glucose homeostasis GO:0042593 128 0.025
purine nucleotide metabolic process GO:0006163 302 0.025
Rat
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.024
response to acid chemical GO:0001101 111 0.024
regulation of cytokine production GO:0001817 266 0.024
carbohydrate metabolic process GO:0005975 230 0.024
stem cell development GO:0048864 219 0.023
positive regulation of mapk cascade GO:0043410 170 0.023
cell adhesion GO:0007155 329 0.023
spermatogenesis GO:0007283 284 0.023
nitrogen compound transport GO:0071705 271 0.023
Rat
immune effector process GO:0002252 321 0.023
g protein coupled receptor signaling pathway GO:0007186 243 0.023
ear development GO:0043583 200 0.023
stem cell differentiation GO:0048863 268 0.023
regulation of defense response GO:0031347 233 0.023
t cell activation GO:0042110 289 0.022
renal system development GO:0072001 225 0.022
posttranscriptional regulation of gene expression GO:0010608 155 0.022
regulation of leukocyte differentiation GO:1902105 159 0.022
carbohydrate homeostasis GO:0033500 128 0.022
cellular response to organonitrogen compound GO:0071417 145 0.022
nucleobase containing small molecule metabolic process GO:0055086 352 0.022
Rat
multicellular organismal homeostasis GO:0048871 164 0.022
cellular response to lipopolysaccharide GO:0071222 77 0.022
cellular ion homeostasis GO:0006873 165 0.022
cellular response to acid chemical GO:0071229 68 0.022
anion transport GO:0006820 177 0.022
ribonucleotide metabolic process GO:0009259 291 0.022
Rat
regulation of t cell activation GO:0050863 170 0.022
cation homeostasis GO:0055080 212 0.021
cellular response to amino acid stimulus GO:0071230 29 0.021
regulation of kinase activity GO:0043549 249 0.021
connective tissue development GO:0061448 179 0.021
aromatic compound catabolic process GO:0019439 286 0.021
Rat
cellular response to cytokine stimulus GO:0071345 189 0.021
positive regulation of defense response GO:0031349 124 0.021
regulation of transferase activity GO:0051338 263 0.021
protein modification by small protein conjugation or removal GO:0070647 207 0.021
regulation of cellular component biogenesis GO:0044087 181 0.021
peptide transport GO:0015833 133 0.021
Rat
cellular metal ion homeostasis GO:0006875 151 0.020
urogenital system development GO:0001655 261 0.020
inflammatory response GO:0006954 244 0.020
nucleotide metabolic process GO:0009117 332 0.020
Rat
positive regulation of apoptotic process GO:0043065 217 0.020
positive regulation of cell development GO:0010720 237 0.020
positive regulation of neuron differentiation GO:0045666 141 0.020
epithelial cell proliferation GO:0050673 174 0.020
positive regulation of nervous system development GO:0051962 221 0.020
rho protein signal transduction GO:0007266 32 0.020
macromolecule catabolic process GO:0009057 281 0.020
cell activation involved in immune response GO:0002263 126 0.020
oxidation reduction process GO:0055114 342 0.020
leukocyte proliferation GO:0070661 172 0.020
cellular response to biotic stimulus GO:0071216 92 0.019
organic cyclic compound catabolic process GO:1901361 295 0.019
Rat
muscle cell differentiation GO:0042692 261 0.019
anatomical structure homeostasis GO:0060249 145 0.019
regulation of cell cycle GO:0051726 281 0.019
cellular response to molecule of bacterial origin GO:0071219 83 0.019
negative regulation of intracellular signal transduction GO:1902532 167 0.019
fat cell differentiation GO:0045444 160 0.019
regulation of cell activation GO:0050865 289 0.019
blood vessel morphogenesis GO:0048514 285 0.019
regulation of cell cycle process GO:0010564 160 0.019
regulation of protein serine threonine kinase activity GO:0071900 157 0.019
regionalization GO:0003002 337 0.019
respiratory tube development GO:0030323 167 0.018
regulation of hormone levels GO:0010817 211 0.018
Mouse Rat
defense response to other organism GO:0098542 197 0.018
learning or memory GO:0007611 148 0.018
Mouse Fly
purine ribonucleoside metabolic process GO:0046128 241 0.018
positive regulation of cell death GO:0010942 224 0.018
calcium ion homeostasis GO:0055074 127 0.018
positive regulation of growth GO:0045927 104 0.018
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.018
mitotic cell cycle GO:0000278 195 0.018
positive regulation of programmed cell death GO:0043068 218 0.018
protein localization to organelle GO:0033365 185 0.018
skeletal muscle organ development GO:0060538 163 0.018
cell type specific apoptotic process GO:0097285 268 0.018
regulation of ion transport GO:0043269 215 0.018
regulation of epithelial cell proliferation GO:0050678 141 0.018
respiratory system development GO:0060541 190 0.018
divalent inorganic cation homeostasis GO:0072507 138 0.018
positive regulation of kinase activity GO:0033674 155 0.017
reactive oxygen species metabolic process GO:0072593 84 0.017
negative regulation of protein metabolic process GO:0051248 282 0.017
regulation of homeostatic process GO:0032844 182 0.017
locomotory behavior GO:0007626 195 0.017
protein modification by small protein conjugation GO:0032446 187 0.017
lung development GO:0030324 164 0.017
carbohydrate derivative biosynthetic process GO:1901137 183 0.017
b cell activation GO:0042113 161 0.017
regulation of protein localization GO:0032880 231 0.017
meiotic nuclear division GO:0007126 115 0.017
circulatory system process GO:0003013 197 0.017
establishment of organelle localization GO:0051656 122 0.017
regulation of secretion by cell GO:1903530 249 0.017
Rat
response to molecule of bacterial origin GO:0002237 143 0.017
peptide secretion GO:0002790 114 0.017
Rat
blood circulation GO:0008015 195 0.017
limb development GO:0060173 166 0.017
positive regulation of lymphocyte activation GO:0051251 140 0.017
regulation of cell motility GO:2000145 236 0.017
digestive system development GO:0055123 200 0.017
regulation of cellular response to stress GO:0080135 159 0.017
protein ubiquitination GO:0016567 171 0.017
regulation of system process GO:0044057 200 0.017
cellular macromolecule catabolic process GO:0044265 206 0.017
membrane organization GO:0061024 245 0.017
actin cytoskeleton organization GO:0030036 220 0.017
chemotaxis GO:0006935 247 0.017
retina development in camera type eye GO:0060041 119 0.017
innate immune response GO:0045087 157 0.017
multicellular organism growth GO:0035264 161 0.017
response to nutrient levels GO:0031667 109 0.017
regulation of apoptotic signaling pathway GO:2001233 197 0.017
cognition GO:0050890 149 0.017
Mouse Fly
nuclear division GO:0000280 158 0.017
central nervous system neuron differentiation GO:0021953 162 0.017
skin development GO:0043588 220 0.016
skeletal system morphogenesis GO:0048705 203 0.016
tissue homeostasis GO:0001894 115 0.016
amide transport GO:0042886 138 0.016
Rat
myeloid leukocyte differentiation GO:0002573 119 0.016
cartilage development GO:0051216 140 0.016
regulation of feeding behavior GO:0060259 3 0.016
positive regulation of cytokine production GO:0001819 174 0.016
t cell differentiation GO:0030217 174 0.016
positive regulation of transferase activity GO:0051347 167 0.016
positive regulation of protein phosphorylation GO:0001934 242 0.016
tissue remodeling GO:0048771 102 0.016
monocarboxylic acid metabolic process GO:0032787 191 0.016
response to growth factor GO:0070848 198 0.016
lipid biosynthetic process GO:0008610 179 0.016
Mouse
forebrain development GO:0030900 302 0.016
response to organic cyclic compound GO:0014070 198 0.016
negative regulation of cellular protein metabolic process GO:0032269 247 0.016
metal ion homeostasis GO:0055065 189 0.016
maintenance of location GO:0051235 89 0.016
response to amino acid GO:0043200 37 0.015
microtubule based process GO:0007017 236 0.015
regulation of leukocyte proliferation GO:0070663 121 0.015
epidermis development GO:0008544 187 0.015
lateral inhibition GO:0046331 1 0.015
Fly
endocytosis GO:0006897 168 0.015
response to extracellular stimulus GO:0009991 127 0.015
regulation of cell projection organization GO:0031344 206 0.015
sequestering of calcium ion GO:0051208 18 0.015
negative regulation of phosphate metabolic process GO:0045936 184 0.015
cellular calcium ion homeostasis GO:0006874 119 0.015
regulation of lymphocyte differentiation GO:0045619 107 0.015
wnt signaling pathway GO:0016055 188 0.015
myeloid cell differentiation GO:0030099 233 0.015
regulation of establishment of protein localization GO:0070201 181 0.015
purine ribonucleotide metabolic process GO:0009150 290 0.015
Rat
cellular protein catabolic process GO:0044257 155 0.015
protein catabolic process GO:0030163 221 0.015
epithelial tube morphogenesis GO:0060562 303 0.015
homeostasis of number of cells GO:0048872 210 0.015
peptidyl amino acid modification GO:0018193 336 0.015
cell maturation GO:0048469 127 0.015
lymphocyte activation involved in immune response GO:0002285 93 0.015
cell fate commitment GO:0045165 210 0.014
Fly
regulation of ossification GO:0030278 112 0.014
organophosphate catabolic process GO:0046434 232 0.014
Rat
muscle cell development GO:0055001 133 0.014
morphogenesis of a branching structure GO:0001763 203 0.014
cell substrate adhesion GO:0031589 130 0.014
axonogenesis GO:0007409 274 0.014
Fly
leukocyte activation involved in immune response GO:0002366 126 0.014
developmental maturation GO:0021700 193 0.014
fertilization GO:0009566 127 0.014
negative regulation of organelle organization GO:0010639 90 0.014
glycosyl compound metabolic process GO:1901657 246 0.014
regulation of cell adhesion GO:0030155 154 0.014
germ cell development GO:0007281 185 0.014
regulation of cytoskeleton organization GO:0051493 122 0.014
chromatin modification GO:0016568 187 0.014
peptide hormone secretion GO:0030072 109 0.014
Rat
striated muscle cell development GO:0055002 125 0.014
hormone secretion GO:0046879 128 0.014
Rat
organelle fission GO:0048285 170 0.014
leukocyte migration GO:0050900 124 0.014
regulation of protein kinase activity GO:0045859 232 0.014
extrinsic apoptotic signaling pathway GO:0097191 126 0.014
positive regulation of cell activation GO:0050867 158 0.014
cellular response to growth factor stimulus GO:0071363 197 0.014
response to light stimulus GO:0009416 135 0.014
Mouse
negative regulation of molecular function GO:0044092 258 0.014
cellular response to dna damage stimulus GO:0006974 207 0.014
organic anion transport GO:0015711 137 0.014
extracellular matrix organization GO:0030198 147 0.014
regulation of mitotic cell cycle GO:0007346 126 0.014
organonitrogen compound catabolic process GO:1901565 264 0.014
Rat
regulation of lipid metabolic process GO:0019216 118 0.014
Mouse
regulation of striated muscle cell differentiation GO:0051153 81 0.014
dna metabolic process GO:0006259 303 0.014
negative regulation of phosphorus metabolic process GO:0010563 184 0.014
regulation of cell migration GO:0030334 219 0.013
negative regulation of phosphorylation GO:0042326 166 0.013
regulation of transmembrane transport GO:0034762 128 0.013
lymphocyte proliferation GO:0046651 164 0.013
conditioned taste aversion GO:0001661 4 0.013
Fly
extracellular structure organization GO:0043062 148 0.013
regulation of proteolysis GO:0030162 164 0.013
intracellular protein transport GO:0006886 204 0.013
heart morphogenesis GO:0003007 178 0.013
nucleoside triphosphate metabolic process GO:0009141 230 0.013
generation of precursor metabolites and energy GO:0006091 103 0.013
spermatid differentiation GO:0048515 115 0.013
positive regulation of leukocyte differentiation GO:1902107 86 0.013
placenta development GO:0001890 140 0.013
regulation of inflammatory response GO:0050727 147 0.013
meiotic cell cycle GO:0051321 122 0.013
sequestering of metal ion GO:0051238 19 0.013
ribose phosphate metabolic process GO:0019693 291 0.013
Rat
organonitrogen compound biosynthetic process GO:1901566 192 0.013
regulation of ion transmembrane transport GO:0034765 119 0.013
positive regulation of t cell activation GO:0050870 101 0.013
purine nucleoside triphosphate metabolic process GO:0009144 226 0.013
regulation of response to wounding GO:1903034 189 0.013
organophosphate biosynthetic process GO:0090407 122 0.013
negative regulation of protein modification process GO:0031400 163 0.013
regulation of reactive oxygen species metabolic process GO:2000377 40 0.012
regulation of t cell proliferation GO:0042129 92 0.012
divalent inorganic cation transport GO:0072511 178 0.012
heterocycle catabolic process GO:0046700 280 0.012
Rat
engulfment of apoptotic cell GO:0043652 3 0.012
organic hydroxy compound metabolic process GO:1901615 203 0.012
nucleoside metabolic process GO:0009116 246 0.012
appendage development GO:0048736 166 0.012
regulation of membrane potential GO:0042391 192 0.012
actin filament organization GO:0007015 113 0.012
chromatin organization GO:0006325 206 0.012
mitotic cell cycle process GO:1903047 159 0.012
synapse organization GO:0050808 125 0.012
adult behavior GO:0030534 135 0.012
limb morphogenesis GO:0035108 149 0.012
regulation of lymphocyte proliferation GO:0050670 117 0.012
ribonucleoside metabolic process GO:0009119 245 0.012
lipid localization GO:0010876 126 0.012
positive regulation of hydrolase activity GO:0051345 148 0.012
regulation of cellular catabolic process GO:0031329 242 0.012
microtubule cytoskeleton organization GO:0000226 157 0.012
bone morphogenesis GO:0060349 78 0.012
response to starvation GO:0042594 65 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.012
response to inorganic substance GO:0010035 96 0.012
histone modification GO:0016570 159 0.012
interferon gamma production GO:0032609 67 0.012
ribonucleoside triphosphate metabolic process GO:0009199 220 0.012
defense response to bacterium GO:0042742 119 0.012
purine nucleoside catabolic process GO:0006152 205 0.012
action potential GO:0001508 78 0.012
intrinsic apoptotic signaling pathway GO:0097193 132 0.012
nucleoside catabolic process GO:0009164 206 0.012
nucleoside triphosphate catabolic process GO:0009143 205 0.012
carbohydrate transport GO:0008643 62 0.012
fatty acid metabolic process GO:0006631 121 0.012
smoothened signaling pathway GO:0007224 105 0.012
purine ribonucleotide catabolic process GO:0009154 208 0.012
Rat
reactive nitrogen species metabolic process GO:2001057 0 0.012
cellular carbohydrate metabolic process GO:0044262 119 0.012
single organism cell adhesion GO:0098602 156 0.012
cellular divalent inorganic cation homeostasis GO:0072503 127 0.012
carbohydrate derivative catabolic process GO:1901136 231 0.012
Rat
muscle system process GO:0003012 141 0.012
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
appendage morphogenesis GO:0035107 149 0.012
negative regulation of cellular component organization GO:0051129 194 0.012
regulation of intracellular transport GO:0032386 159 0.012
positive regulation of protein kinase activity GO:0045860 144 0.012
purine nucleoside metabolic process GO:0042278 241 0.012
detection of abiotic stimulus GO:0009582 60 0.011
negative regulation of immune system process GO:0002683 209 0.011
modification dependent protein catabolic process GO:0019941 133 0.011
neuron migration GO:0001764 122 0.011
regulation of cell growth GO:0001558 91 0.011
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.011
gonad development GO:0008406 141 0.011
translation GO:0006412 93 0.011
leukocyte mediated immunity GO:0002443 174 0.011
regulation of t cell differentiation GO:0045580 83 0.011
divalent metal ion transport GO:0070838 172 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.011
purine containing compound biosynthetic process GO:0072522 70 0.011
response to oxidative stress GO:0006979 123 0.011
adaptive immune response GO:0002250 155 0.011
stem cell proliferation GO:0072089 117 0.011
mrna metabolic process GO:0016071 84 0.011
cellular protein complex assembly GO:0043623 116 0.011
hexose metabolic process GO:0019318 98 0.011
embryonic skeletal system development GO:0048706 120 0.011
methylation GO:0032259 134 0.011
lymphocyte mediated immunity GO:0002449 139 0.011
cell growth GO:0016049 130 0.011
Fly
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.011
nucleotide biosynthetic process GO:0009165 78 0.011
negative regulation of synapse assembly GO:0051964 3 0.011
nucleoside phosphate biosynthetic process GO:1901293 79 0.011
neural tube development GO:0021915 160 0.011
regulation of fat cell differentiation GO:0045598 81 0.011
ribonucleoside catabolic process GO:0042454 206 0.011
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.011
wound healing GO:0042060 157 0.011
oocyte construction GO:0007308 2 0.011
cell matrix adhesion GO:0007160 68 0.011
epithelial cell development GO:0002064 159 0.011
bone resorption GO:0045453 38 0.011
purine nucleoside triphosphate catabolic process GO:0009146 203 0.011
rna processing GO:0006396 105 0.011
positive regulation of cellular catabolic process GO:0031331 148 0.011
protein targeting GO:0006605 143 0.011
neurotransmitter transport GO:0006836 76 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.011
bone development GO:0060348 120 0.011
glucose metabolic process GO:0006006 92 0.011
regulation of map kinase activity GO:0043405 120 0.011
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
regulation of organ growth GO:0046620 61 0.011
activation of immune response GO:0002253 138 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.010
protein localization to nucleus GO:0034504 121 0.010
embryonic placenta development GO:0001892 98 0.010
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.010
ribonucleotide biosynthetic process GO:0009260 59 0.010
cytokine mediated signaling pathway GO:0019221 115 0.010
spermatid development GO:0007286 108 0.010
response to radiation GO:0009314 165 0.010
Mouse
ribonucleotide catabolic process GO:0009261 208 0.010
Rat
nucleocytoplasmic transport GO:0006913 139 0.010
small molecule biosynthetic process GO:0044283 132 0.010
learning GO:0007612 98 0.010
Mouse Fly
glucose transport GO:0015758 56 0.010
developmental growth involved in morphogenesis GO:0060560 138 0.010
Fly
single fertilization GO:0007338 82 0.010
calcium ion transport GO:0006816 159 0.010
glycoprotein metabolic process GO:0009100 116 0.010
angiogenesis GO:0001525 201 0.010
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.010
rna interference GO:0016246 2 0.010
cellular response to hormone stimulus GO:0032870 150 0.010
olfactory learning GO:0008355 2 0.010
morphogenesis of a branching epithelium GO:0061138 193 0.010
energy derivation by oxidation of organic compounds GO:0015980 77 0.010
cell division GO:0051301 120 0.010
positive regulation of cellular component biogenesis GO:0044089 94 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.010
response to oxygen levels GO:0070482 62 0.010
positive regulation of phospholipase activity GO:0010518 3 0.010
regulation of muscle system process GO:0090257 80 0.010
gastrulation GO:0007369 116 0.010

Pde4c disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
nervous system disease DOID:863 0 0.029
sensory system disease DOID:0050155 0 0.016
disease of cellular proliferation DOID:14566 0 0.015
cancer DOID:162 0 0.013
organ system cancer DOID:0050686 0 0.013