Mus musculus

0 known processes

Papolb

poly (A) polymerase beta (testis specific)

(Aliases: PAP,Plap-ps,Papola-ps,Papt,Tpap,Paplob)

Papolb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
amine metabolic process GO:0009308 45 0.227
organic hydroxy compound metabolic process GO:1901615 203 0.111
response to inorganic substance GO:0010035 96 0.103
oxidation reduction process GO:0055114 342 0.103
rhodopsin mediated signaling pathway GO:0016056 4 0.093
striated muscle tissue development GO:0014706 293 0.079
organonitrogen compound biosynthetic process GO:1901566 192 0.076
positive regulation of cellular amine metabolic process GO:0033240 5 0.075
regulation of apoptotic signaling pathway GO:2001233 197 0.072
macromolecule catabolic process GO:0009057 281 0.070
regulation of cellular amine metabolic process GO:0033238 20 0.069
protein maturation GO:0051604 176 0.068
reactive oxygen species metabolic process GO:0072593 84 0.062
multicellular organismal homeostasis GO:0048871 164 0.061
germ cell development GO:0007281 185 0.060
Worm
negative regulation of molecular function GO:0044092 258 0.056
regulation of cellular amino acid metabolic process GO:0006521 5 0.056
regulation of kinase activity GO:0043549 249 0.055
anatomical structure homeostasis GO:0060249 145 0.054
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.053
muscle tissue development GO:0060537 308 0.050
spermatogenesis GO:0007283 284 0.049
positive regulation of transferase activity GO:0051347 167 0.049
cytoplasmic transport GO:0016482 234 0.049
cellular alcohol biosynthetic process GO:0044108 3 0.049
negative regulation of cellular protein metabolic process GO:0032269 247 0.047
cellular amine metabolic process GO:0044106 44 0.047
fertilization GO:0009566 127 0.047
membrane organization GO:0061024 245 0.046
protein modification by small protein conjugation or removal GO:0070647 207 0.046
mitochondrion organization GO:0007005 134 0.045
glycoprotein metabolic process GO:0009100 116 0.044
regulation of transferase activity GO:0051338 263 0.044
binding of sperm to zona pellucida GO:0007339 34 0.044
intracellular protein transport GO:0006886 204 0.042
epithelial cell proliferation GO:0050673 174 0.041
regulation of cell motility GO:2000145 236 0.041
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.040
pigmentation GO:0043473 71 0.039
inflammatory response GO:0006954 244 0.039
regulation of cell migration GO:0030334 219 0.038
extracellular structure organization GO:0043062 148 0.038
regulation of protein processing GO:0070613 96 0.038
muscle cell differentiation GO:0042692 261 0.038
b cell differentiation GO:0030183 78 0.037
calcium mediated signaling GO:0019722 46 0.037
keratinocyte proliferation GO:0043616 21 0.037
myeloid cell differentiation GO:0030099 233 0.036
regulation of lipid metabolic process GO:0019216 118 0.036
protein ubiquitination GO:0016567 171 0.036
extracellular matrix organization GO:0030198 147 0.036
heart morphogenesis GO:0003007 178 0.035
extrinsic apoptotic signaling pathway GO:0097191 126 0.035
aromatic compound catabolic process GO:0019439 286 0.035
cellular amino acid metabolic process GO:0006520 103 0.035
cell recognition GO:0008037 83 0.035
regulation of epithelial cell proliferation GO:0050678 141 0.035
cellular response to hormone stimulus GO:0032870 150 0.034
ribose phosphate metabolic process GO:0019693 291 0.034
pigment metabolic process GO:0042440 32 0.033
positive regulation of protein modification process GO:0031401 299 0.033
cell chemotaxis GO:0060326 81 0.033
rhythmic process GO:0048511 174 0.032
single fertilization GO:0007338 82 0.032
blood vessel morphogenesis GO:0048514 285 0.032
regulation of mitotic cell cycle GO:0007346 126 0.032
cellular response to oxidative stress GO:0034599 76 0.032
regulation of response to wounding GO:1903034 189 0.032
multicellular organism growth GO:0035264 161 0.032
cellular ketone metabolic process GO:0042180 84 0.032
positive regulation of thymocyte migration GO:2000412 2 0.032
carbohydrate metabolic process GO:0005975 230 0.031
multicellular organismal signaling GO:0035637 91 0.031
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.031
divalent metal ion transport GO:0070838 172 0.030
transmembrane transport GO:0055085 412 0.030
negative regulation of apoptotic signaling pathway GO:2001234 104 0.030
male gamete generation GO:0048232 285 0.030
ribonucleotide metabolic process GO:0009259 291 0.029
neural precursor cell proliferation GO:0061351 121 0.029
response to acid chemical GO:0001101 111 0.028
positive regulation of keratinocyte proliferation GO:0010838 4 0.028
signal transduction in absence of ligand GO:0038034 55 0.028
extracellular matrix dependent thymocyte migration GO:0072680 1 0.028
regulation of intracellular transport GO:0032386 159 0.028
regulation of tumor necrosis factor ligand superfamily member 11 production GO:2000307 1 0.028
nucleotide metabolic process GO:0009117 332 0.028
cellular response to external stimulus GO:0071496 88 0.028
cellular response to organonitrogen compound GO:0071417 145 0.027
ribonucleotide catabolic process GO:0009261 208 0.027
cellular response to peptide GO:1901653 92 0.027
regulation of cell projection organization GO:0031344 206 0.027
response to reactive oxygen species GO:0000302 56 0.027
inorganic cation transmembrane transport GO:0098662 207 0.027
response to oxidative stress GO:0006979 123 0.027
positive regulation of angiogenesis GO:0045766 46 0.027
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.027
heterocycle catabolic process GO:0046700 280 0.027
nucleoside triphosphate catabolic process GO:0009143 205 0.026
ensheathment of neurons GO:0007272 76 0.026
protein targeting GO:0006605 143 0.026
ion transmembrane transport GO:0034220 361 0.026
eosinophil migration GO:0072677 3 0.026
negative regulation of protein metabolic process GO:0051248 282 0.026
regulation of cellular ketone metabolic process GO:0010565 66 0.025
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.025
hematopoietic progenitor cell differentiation GO:0002244 143 0.025
myelination GO:0042552 74 0.025
asymmetric stem cell division GO:0098722 3 0.025
positive regulation of cell motility GO:2000147 116 0.024
regulation of protein kinase activity GO:0045859 232 0.024
protein catabolic process GO:0030163 221 0.024
lipid biosynthetic process GO:0008610 179 0.024
maintenance of location GO:0051235 89 0.024
digestive system development GO:0055123 200 0.024
spermatid differentiation GO:0048515 115 0.024
cellular lipid metabolic process GO:0044255 323 0.023
chemotaxis GO:0006935 247 0.023
ribonucleoside triphosphate metabolic process GO:0009199 220 0.023
glucose homeostasis GO:0042593 128 0.023
chromatin modification GO:0016568 187 0.023
cardiac muscle tissue development GO:0048738 130 0.022
regulation of microvillus organization GO:0032530 3 0.022
mitotic cell cycle GO:0000278 195 0.022
midgut development GO:0007494 4 0.022
apoptotic signaling pathway GO:0097190 306 0.022
nitrogen compound transport GO:0071705 271 0.022
regulation of hormone levels GO:0010817 211 0.022
regulation of cell cycle GO:0051726 281 0.022
response to metal ion GO:0010038 47 0.022
positive regulation of kinase activity GO:0033674 155 0.021
nucleoside phosphate catabolic process GO:1901292 222 0.021
cation transport GO:0006812 399 0.021
nuclear division GO:0000280 158 0.021
cellular response to growth factor stimulus GO:0071363 197 0.021
nucleoside catabolic process GO:0009164 206 0.021
cellular response to peptide hormone stimulus GO:0071375 92 0.021
response to radiation GO:0009314 165 0.021
learning or memory GO:0007611 148 0.021
ventricular cardiac muscle tissue development GO:0003229 38 0.021
gland development GO:0048732 330 0.021
carbohydrate derivative biosynthetic process GO:1901137 183 0.021
positive regulation of protein phosphorylation GO:0001934 242 0.021
protein processing GO:0016485 163 0.021
regulation of ion homeostasis GO:2000021 64 0.021
thymocyte migration GO:0072679 2 0.020
establishment or maintenance of cell polarity GO:0007163 86 0.020
cell adhesion GO:0007155 329 0.020
olfactory learning GO:0008355 2 0.020
regulation of eosinophil migration GO:2000416 2 0.020
sequestering of calcium ion GO:0051208 18 0.020
regulation of inflammatory response GO:0050727 147 0.020
asymmetric neuroblast division GO:0055059 1 0.020
tissue homeostasis GO:0001894 115 0.020
adult locomotory behavior GO:0008344 91 0.020
cellular response to inorganic substance GO:0071241 37 0.020
establishment of blood nerve barrier GO:0008065 3 0.020
phenol containing compound metabolic process GO:0018958 60 0.020
purine nucleotide catabolic process GO:0006195 211 0.019
striated muscle cell development GO:0055002 125 0.019
cell cell recognition GO:0009988 44 0.019
positive regulation of cell death GO:0010942 224 0.019
nucleoside triphosphate metabolic process GO:0009141 230 0.019
negative regulation of cell proliferation GO:0008285 296 0.019
cellular response to lipid GO:0071396 145 0.019
lung pattern specification process GO:0060432 1 0.019
purine containing compound catabolic process GO:0072523 213 0.019
glycosyl compound metabolic process GO:1901657 246 0.019
embryonic organ morphogenesis GO:0048562 276 0.019
response to growth factor GO:0070848 198 0.019
insulin secretion GO:0030073 89 0.019
ameboidal type cell migration GO:0001667 128 0.019
action potential GO:0001508 78 0.019
activation of mapk activity involved in innate immune response GO:0035419 2 0.019
chromatin organization GO:0006325 206 0.019
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.019
regulation of homeostatic process GO:0032844 182 0.019
regulation of cellular catabolic process GO:0031329 242 0.019
sensory perception of sound GO:0007605 97 0.019
small gtpase mediated signal transduction GO:0007264 97 0.019
meiotic cell cycle process GO:1903046 77 0.019
peptide metabolic process GO:0006518 46 0.018
cell type specific apoptotic process GO:0097285 268 0.018
axon ensheathment GO:0008366 76 0.018
nucleobase containing small molecule metabolic process GO:0055086 352 0.018
response to temperature stimulus GO:0009266 55 0.018
lung development GO:0030324 164 0.018
development of primary sexual characteristics GO:0045137 143 0.018
Worm
hormone metabolic process GO:0042445 86 0.018
inner ear receptor cell development GO:0060119 39 0.018
cognition GO:0050890 149 0.018
negative regulation of synapse maturation GO:2000297 2 0.018
skin development GO:0043588 220 0.017
purine ribonucleotide metabolic process GO:0009150 290 0.017
cellular macromolecule catabolic process GO:0044265 206 0.017
fat soluble vitamin biosynthetic process GO:0042362 4 0.017
methylation GO:0032259 134 0.017
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.017
negative regulation of cellular component organization GO:0051129 194 0.017
regulation of binding GO:0051098 111 0.017
endocytosis GO:0006897 168 0.017
feeding behavior GO:0007631 62 0.017
regulation of membrane protein ectodomain proteolysis GO:0051043 3 0.017
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.017
regulation of metal ion transport GO:0010959 106 0.017
glial cell differentiation GO:0010001 131 0.017
positive regulation of tissue remodeling GO:0034105 19 0.017
spermatid development GO:0007286 108 0.017
purine ribonucleoside metabolic process GO:0046128 241 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.016
sperm egg recognition GO:0035036 37 0.016
lipid localization GO:0010876 126 0.016
transmission of nerve impulse GO:0019226 76 0.016
response to hydrogen peroxide GO:0042542 32 0.016
positive regulation of protein kinase activity GO:0045860 144 0.016
regulation of chromosome organization GO:0033044 83 0.016
sialylation GO:0097503 14 0.016
response to peptide GO:1901652 136 0.016
insulin receptor signaling pathway GO:0008286 49 0.016
regulation of systemic arterial blood pressure GO:0003073 61 0.016
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.016
regulation of complement activation classical pathway GO:0030450 1 0.016
regulation of organelle organization GO:0033043 289 0.016
negative regulation of phosphorus metabolic process GO:0010563 184 0.016
positive regulation of response to wounding GO:1903036 66 0.016
response to organonitrogen compound GO:0010243 246 0.016
regulation of microvillus assembly GO:0032534 3 0.016
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 4 0.016
protein activation cascade GO:0072376 19 0.016
ribonucleoside catabolic process GO:0042454 206 0.016
organelle localization GO:0051640 179 0.015
sequestering of metal ion GO:0051238 19 0.015
divalent inorganic cation transport GO:0072511 178 0.015
small molecule biosynthetic process GO:0044283 132 0.015
response to heat GO:0009408 27 0.015
photoreceptor cell differentiation GO:0046530 52 0.015
positive regulation of tumor necrosis factor ligand superfamily member 11 production GO:2000309 1 0.015
regulation of proteolysis GO:0030162 164 0.015
myotube differentiation GO:0014902 105 0.015
protein modification by small protein conjugation GO:0032446 187 0.015
organophosphate catabolic process GO:0046434 232 0.015
mitochondrion distribution GO:0048311 4 0.015
negative regulation of cellular amine metabolic process GO:0033239 1 0.015
regulation of neuron death GO:1901214 134 0.015
positive regulation of membrane protein ectodomain proteolysis GO:0051044 3 0.015
fibronectin dependent thymocyte migration GO:0072681 1 0.015
organelle fission GO:0048285 170 0.015
tissue kallikrein kinin cascade GO:0002255 1 0.015
nucleoside metabolic process GO:0009116 246 0.015
negative regulation of protein processing GO:0010955 79 0.015
anion transmembrane transport GO:0098656 71 0.015
purine nucleotide metabolic process GO:0006163 302 0.015
regulation of striated muscle cell differentiation GO:0051153 81 0.015
negative regulation of protein modification process GO:0031400 163 0.015
carbohydrate derivative catabolic process GO:1901136 231 0.015
regulation of stem cell proliferation GO:0072091 78 0.015
ovulation cycle GO:0042698 59 0.015
negative regulation of transferase activity GO:0051348 85 0.014
protein import GO:0017038 101 0.014
regulation of protein maturation GO:1903317 96 0.014
positive regulation of fibronectin dependent thymocyte migration GO:2000415 1 0.014
regulation of neural precursor cell proliferation GO:2000177 70 0.014
organic cyclic compound catabolic process GO:1901361 295 0.014
fat cell differentiation GO:0045444 160 0.014
innate immune response GO:0045087 157 0.014
cellular nitrogen compound catabolic process GO:0044270 280 0.014
digestive tract morphogenesis GO:0048546 147 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.014
negative regulation of protein maturation GO:1903318 79 0.014
alcohol metabolic process GO:0006066 116 0.014
positive regulation of eosinophil migration GO:2000418 2 0.014
regulation of neural retina development GO:0061074 3 0.014
negative regulation of organelle organization GO:0010639 90 0.014
vesicle localization GO:0051648 86 0.014
response to testosterone GO:0033574 3 0.014
mechanoreceptor differentiation GO:0042490 67 0.014
respiratory system development GO:0060541 190 0.014
protein kinase b signaling GO:0043491 74 0.014
retina development in camera type eye GO:0060041 119 0.014
skeletal muscle organ development GO:0060538 163 0.014
peptidyl amino acid modification GO:0018193 336 0.013
response to transforming growth factor beta GO:0071559 88 0.013
purine ribonucleoside catabolic process GO:0046130 205 0.013
dna repair GO:0006281 107 0.013
fat cell proliferation GO:0070341 4 0.013
endomembrane system organization GO:0010256 147 0.013
leukocyte differentiation GO:0002521 342 0.013
purine nucleoside monophosphate metabolic process GO:0009126 81 0.013
stem cell differentiation GO:0048863 268 0.013
wnt signaling pathway GO:0016055 188 0.013
protein acylation GO:0043543 64 0.013
regulation of neuron apoptotic process GO:0043523 122 0.013
prevention of polyspermy GO:0060468 4 0.013
positive regulation of cell migration GO:0030335 109 0.013
glycosylation GO:0070085 62 0.013
progesterone metabolic process GO:0042448 4 0.013
protein localization to organelle GO:0033365 185 0.013
establishment of protein localization to organelle GO:0072594 118 0.013
cytosolic calcium ion transport GO:0060401 48 0.013
meiosis i GO:0007127 60 0.012
angiogenesis GO:0001525 201 0.012
negative regulation of protein activation cascade GO:2000258 3 0.012
single organism nuclear import GO:1902593 95 0.012
regulation of ion transport GO:0043269 215 0.012
regulation of protein kinase b signaling GO:0051896 56 0.012
glycosyl compound catabolic process GO:1901658 206 0.012
associative learning GO:0008306 61 0.012
notch signaling pathway GO:0007219 71 0.012
smoothened signaling pathway GO:0007224 105 0.012
modification dependent macromolecule catabolic process GO:0043632 133 0.012
regulation of monocyte extravasation GO:2000437 2 0.012
regulation of cellular response to growth factor stimulus GO:0090287 82 0.012
negative regulation of proteolysis GO:0045861 74 0.012
myeloid leukocyte migration GO:0097529 57 0.012
purine nucleoside triphosphate catabolic process GO:0009146 203 0.012
negative regulation of endothelial cell migration GO:0010596 4 0.012
steroid metabolic process GO:0008202 119 0.012
peptidyl lysine modification GO:0018205 77 0.012
ribonucleoside metabolic process GO:0009119 245 0.012
glycoprotein biosynthetic process GO:0009101 89 0.012
regulation of protein serine threonine kinase activity GO:0071900 157 0.012
negative regulation of protein phosphorylation GO:0001933 126 0.012
regulation of thymocyte migration GO:2000410 2 0.012
regulation of lipid biosynthetic process GO:0046890 54 0.012
regulation of leukocyte differentiation GO:1902105 159 0.012
sensory perception GO:0007600 245 0.012
chromosome organization involved in meiosis GO:0070192 39 0.012
vitamin metabolic process GO:0006766 23 0.011
positive regulation of programmed cell death GO:0043068 218 0.011
meiotic nuclear division GO:0007126 115 0.011
vasoconstriction GO:0042310 27 0.011
dephosphorylation GO:0016311 129 0.011
regulation of fibronectin dependent thymocyte migration GO:2000413 1 0.011
regulation of angiogenesis GO:0045765 81 0.011
peptide hormone secretion GO:0030072 109 0.011
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 34 0.011
female sex differentiation GO:0046660 84 0.011
sensory perception of mechanical stimulus GO:0050954 107 0.011
neuroblast differentiation GO:0014016 2 0.011
cellular protein catabolic process GO:0044257 155 0.011
protein localization to membrane GO:0072657 108 0.011
negative regulation of phosphorylation GO:0042326 166 0.011
positive regulation of bone resorption GO:0045780 13 0.011
ubiquitin dependent protein catabolic process GO:0006511 129 0.011
regulation of cellular protein catabolic process GO:1903362 61 0.011
urogenital system development GO:0001655 261 0.011
vascular process in circulatory system GO:0003018 62 0.011
tissue migration GO:0090130 68 0.011
regulation of cellular response to stress GO:0080135 159 0.011
cellular response to gonadotropin stimulus GO:0071371 4 0.011
myeloid leukocyte differentiation GO:0002573 119 0.011
positive regulation of mapk cascade GO:0043410 170 0.011
circadian rhythm GO:0007623 114 0.011
inner ear receptor cell differentiation GO:0060113 61 0.011
regulation of chromatin organization GO:1902275 57 0.011
c21 steroid hormone biosynthetic process GO:0006700 3 0.011
positive regulation of hormone metabolic process GO:0032352 3 0.011
regulation of cytoplasmic transport GO:1903649 112 0.011
locomotory behavior GO:0007626 195 0.010
regulation of cell cycle process GO:0010564 160 0.010
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.010
synapsis GO:0007129 34 0.010
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 26 0.010
regulation of monocyte chemotaxis GO:0090025 3 0.010
sulfur compound metabolic process GO:0006790 100 0.010
establishment of vesicle localization GO:0051650 81 0.010
nuclear import GO:0051170 95 0.010
synaptic vesicle localization GO:0097479 59 0.010
cellular alcohol metabolic process GO:0044107 3 0.010
regulation of tissue remodeling GO:0034103 38 0.010
epidermis development GO:0008544 187 0.010
organophosphate biosynthetic process GO:0090407 122 0.010
sclerotome development GO:0061056 4 0.010
cholesterol homeostasis GO:0042632 44 0.010
positive regulation of inflammatory response GO:0050729 47 0.010
regulation of multi organism process GO:0043900 111 0.010
activation of adenylate cyclase activity GO:0007190 4 0.010
cellular response to follicle stimulating hormone stimulus GO:0071372 1 0.010
leukocyte chemotaxis GO:0030595 69 0.010
sperm motility GO:0030317 47 0.010
regulation of oxidative phosphorylation uncoupler activity GO:2000275 3 0.010
regulation of reactive oxygen species metabolic process GO:2000377 40 0.010
somite development GO:0061053 81 0.010
transition metal ion transport GO:0000041 38 0.010
posttranscriptional regulation of gene expression GO:0010608 155 0.010
nuclear transport GO:0051169 139 0.010
organelle assembly GO:0070925 177 0.010
epithelial cell development GO:0002064 159 0.010
epithelial tube morphogenesis GO:0060562 303 0.010

Papolb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.059
nervous system disease DOID:863 0 0.059
retinal disease DOID:5679 0 0.027
sensory system disease DOID:0050155 0 0.027
eye and adnexa disease DOID:1492 0 0.027
eye disease DOID:5614 0 0.027
retinal degeneration DOID:8466 0 0.021
retinitis pigmentosa DOID:10584 0 0.017
disease of metabolism DOID:0014667 0 0.017
inherited metabolic disorder DOID:655 0 0.017
central nervous system disease DOID:331 0 0.014
neurodegenerative disease DOID:1289 0 0.012